Introduction

Degenerative disc disease results from mechanical alteration of the intervertebral disc. Biochemical modifications of the nucleus matrix are also incriminated. Furthermore, genetic predispositions as well as vascular factors have been advocated in the process of disc degeneration. A relationship between sciatica and Propionibacterium acnes has been described. However, it remains unclear if the hypothesis of a subclinical spondylodiscitis might play a role in the pathophysiology of degenerative disc disease. The purpose of this study was to analyze the possible presence of bacteria in lumbar discs of patients with degenerative disc disease.

Introduction

Surgical treatment of spinal metastasis belongs to the standards of oncology. The risk of spinal cord compression represents an operative indication. Intraoperative bleeding may vary, depending on the extent of the surgical technique. Some primary tumors, such as the renal cell carcinoma, present a major risk for hemorrhage and preoperative embolisation is mandatory. The purpose of this study is to evaluate the possible benefit of embolisation in different types of primary tumors.

Introduction: The lumbosacral medulla is vascularized by the Adamkiewicz arteria which irrigates the anterior spinal arteria. Occlusion or section of the Adamkiewicz arteria may induce an ischemia of the medulla during anterior or transforaminal spine surgery. An angiography allows to determine the exact topography of this artery. The purpose of this study was to describe its preoperative topography and to analyze the impact of angiography on the surgical strategy.

Methods: In this retrospective study, 100 preoperative medullar angiographies, performed by a vascular radiologist between january 1998 and august 2007, were reviewed. Surgical indications were: 50 vertebrectomies in tumors, 20 anterior fusions in dorsolumbar fractures, 10 anterior fusions in malunions, 10 anterior releases in scoliosis, 3 transpedicular osteotomies, 7 disc hernias (T7-L4). The level and the side of foraminal entrance of the Adamkiewicz arteria and collateral arterias irrigating the anterior spinal arteria were analyzed. We looked for the occurence of postoperative ischemic signs of the medulla. Modifications of surgical planning because of Adamkiewicz’ arteria topography were noted. The possibilities of preoperative tumor embolisation were analyzed.

Results: The Adamkiewicz arteria was always localized between T8 and L3. It was present at the foraminal levels L1/L2 or L2/L3 in 48% of the cases. The left side was concerned in 65% of the cases. A modification of the surgical strategy was noted in 16% of the cases: 12 side changements of operative approach, 4 contra-indications for anterior surgery. An ischemic syndrome of the anterior lumbosacral medulla were not found. In the group of tumors, the preoperative angiography allowed to perform a selective embolisation of tumor vessels in 80% of the cases. In all other cases, the tumor vascularisation was common with the vascularisation of the medulla which could have made the embolisation dangerous.

Conclusion: Although the occurence of a lumbosacral medullar ischemia secondary to an Adamkiewicz arteria lesion is rarely reported in the literature, the preoperative angiography reduces this potential risk. The exact knowledge of the anterior medullar vascularisation allows to better plan the surgical strategy and to adapt the side of operative approach. Furthermore, the angiography enables to perform a selective embolisation of tumors safely.

Scoliosis requires three dimensional correction at a global level (curve correction) and at a local one (apical axial derotation) as well as sagittal balance management. Except for in situ contouring, previously reported surgical techniques for scoliosis correction hardly deal with all these issues. The aim of the current study was to evaluate long term clinical and radiological outcomes after in situ contouring in 85 patients with severe scoliosis (Cobb= 40 to 110°). Age influence (adults versus adolescents) and surgical approaches (anterior release and posterior correction and fusion versus posterior correction and fusion only) were also assessed. The results of the study show that the in situ contouring is comparable to other surgical techniques in terms of surgery duration and blood loss. Anterior release proved useful in severe scoliosis correction. No difference in peroperative complications was found between age groups nor between approach groups. However, adolescents recover faster than adults. No difference of revision rates in double approach versus posterior approach populations was found. No statistically significant differences were found between the adolescent and adult populations. The mean overall frontal correction reached 68%. The mean loss of correction amounted 5%. No significant evolution was found in sagittal curvatures, emphasizing the difficulties in restoring physiological curvatures in patients with severe scoliosis. Our results suggest the in situ contouring technique is fully appropriate for severe scoliosis correction, regardless of the patient’s age and approach. Besides it will not result in higher morbidity for one specific population and warrants similar outcome when properly applied.

Introduction: Surgical treatment of thoracolumbar spine fractures from T11 to L2 with correction of the traumatic kyphosis should be expected to avoid the deceptions observed with former treatments.

Material and methods: Seventy trauma victims (41 men and 29 women) underwent surgery between 1996 and 2003. According to the Denis classification, they presented: 16 compressions, 43 burst fractures, 8 seat belt fractures, and 3 disclocations. The Frankel classification was E:62, A:2, C2, D:2. Mean follow-up was 30.7 months. A pedicle screw protected with sublaminal hooks below and pediculotransverse claws above was used in 50 patients with a hybrid configuration in 20. Reduction was achieved by in situ cerclage. A secondary anterior graft was implanted for 38 patients.

Results: Patients were allowed to rise without contention on day 3. The traumatic angle measured with the sagittal index of Farcy (SIF) (the quality parameter used to study reduction) was 17 preoperatively and 1.6 after surgery. The loss at last follow-up was −2.2° with 81% of patients presenting normal or over correction. The loss was greatest (5.2°) for uniquely posterior approaches. The final Oswestry score was 29.8 (range 6–80) with a better result for the double approaches (20.7 versus 37.4, p< 0.001). Complications were phlebitis (n=1), sutured dural breaches (n=2), disassembly and nonunion (revision with a double approach) (n=1), infection (treated by wash-out and antibiotics) (n=10), retroperitoneal hematoma (treated by embolization) (n=1). Thirty-two patients resumed their work at seven months on average and 13 did not (25 without professional occupation).

Discussion: The overall results are better than those after orthopedic treatment. The rate of resumed work was 71%. This is an excellent result with a less aggressive treatment protocol (no corset) and shorter hospital stay (5–19 days). The protective hooks facilitate in situ cerclage, avoiding catching the screws and the risk of disassembly. The anterior graft is necessary when the reduction is discal and reduces the angle loss leading to less morbidity.

Conclusion: In situ cerclage enables constant sustained reduction of thoracolumbar fractures. Indication for surgery is often retained because of major deformation. Spinal fractures should be examined with the same assessment criteria as used for fractures of long bones and weight bearing should begin early to avoid the risks associated with prolonged bed rest.