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Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_II | Pages 198 - 198
1 May 2011
Anagnostakos K Jung J Kelm J Schmitt E Schmid N
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There exist 4 methods for femoral fixation of hip spacers:

a simple insertion,

a partial/full cementation,

the “glove”-technique, and,

a cement bridge in case of large osseous defects of the proximal femur.

To our knowledge, it is still unknown which of these methods provides the best stability.

Between 01.01.1999–31.12.2008, 84 hip spacer implantations in 78 patients have been performed in our department. All patients have been treated with the same kind of spacer. 24 spacers have been fixed with the “glove”-technique, 18 with a partial cementation onto the proximal femur, 21 with a simple insertion, and 4 with a cement bridge. In 17 cases with an isolated septic loosening of the acetabular cup, only a spacer head has been placed onto the well-fixed prosthesis stem.

The overall dislocation rate between stages was 21.4 % (18/84). The lowest dislocation rate was observed in the “spacer head” group with 5.8 % (1/17), followed by the “glove”-technique with 12.5 % of the cases (3/24). In the “partial cementation” group the dislocation rate was 22.2 % (4/18), whereas in the “insertion” group spacer dislocations occurred in 9 out of 21 cases (42.8 %). In the latter group, in 3 cases the spacer rotated primarily in the femur and dislocated subsequently out from the acetabulum. From the 4 patients having been treated with a cement bridge, 2 patients suffered from a spacer dislocation. From these 18 cases, 15 patients have been treated conservatively by reduction and immobilization in a hip orthesis during the remaining time between stages. The other three cases underwent further surgical procedures; in one case (combined spacer dislocation and -fracture), the spacer had been exchanged, whereas the other two cases had been treated by resection arthroplasty after recurrent spacer dislocations and unsuccessful conservative treatment.

The “glove”-technique seems to be the most effective method for femoral fixation fixation of hip spacers regarding the prevention of dislocations between stages. Further advantages of this technique include a safe and easy spacer explantation in one piece without cement debris at the second stage.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 573 - 573
1 Oct 2010
Lorbach O Anagnostakos K Kohn D Pape D Scherf C
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Background: Comparison of intra-articular corticoid injections and oral corticosteroids in the treatment of adhesive capsulitis of the shoulder

Methods: In a prospective randomized evaluation two different treatment regimen were compared. 40 patients with idiopathic adhesive capsulitis of the shoulder were treated either with an oral (20) corticoid treatment regimen for 4 weeks or intra-articular (20) injection series of corticosteroids (3 injections- 4, 8, 12 weeks).Patient groups were comparable in sex, age and affected side. Follow-up periods were after 4,8,12 weeks, 6 and 12 months. For the clinical evaluation the Constant and Murley Score, the Simple Shoulder Test and visual analog scales for pain, function and satisfaction were used.

Results: In the patients group treated with oral glucocorticoids significant improvements were found for the Constant and Murley Score (p< .0001), the Simple Shoulder Test (p=.035) and range of motion for flexion (p< .0001), abduction (p< .0001), external (p=.001) and internal rotation (p=.028) already at 4 weeks follow-up. The visual analog scales for pain, function and patient satisfaction also improved significantly after 4 weeks of treatment (p< .0001).)

The patient group treated with an intra-articular glucocorticoid injection series also showed significant improvements for the Constant and Murley Score (p< .0001), the Simple Shoulder Test (p< .0001) and the visual analog scales for pain, function and patient satisfaction (p< .0001) after 4 weeks and also at any other follow up. Significant improvements were also seen in abduction (p< .0001), flexion (p< .0001) and external rotation (p=.001) and internal rotation (p=.035) after 4 weeks of treatment. These results were confirmed at any other follow up.

Comparison of the two treatment regimen showed superior short term results for the intra-articular treatment regimen in range of motion, Constant Score and Simple Shoulder Test and patient satisfaction (p< .05). No significant differences were found in the visual analog scales for pain and function (p> .05).

Conclusion: The use of cortisone in the treatment of idiopathic adhesive capsulitis of the shoulder leads to fast pain relief and improves range of motion. Intra-articular injections of glucocorticoids showed superior short term results in objective shoulder scores, range of motion and patient satisfaction compared with a short course of oral corticosteroids.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 605 - 605
1 Oct 2010
Anagnostakos K Kelm J Kristen A Schmitt E
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Introduction: The aim of the present study was to evaluate the efficacy of the vacuum–assisted closure (V.A.C.) therapy in the treatment of early hip joint infections.

Patients and Methods: 28 patients (11 m/17 f; mean age 71 y. [43–84]) with early hip joint infections have been treated by means of the V.A.C.–therapy. At least one surgical procedure [1–7] has been unsuccessfully performed for infection treatment prior to V.A.C. – application. Pathogen organisms could have been isolated in 22/28 wounds. During revision, cup inlay and prosthesis head have been exchanged and 1–3 polyvinylalcohol sponges inserted into the wound cavity/periprosthetically at an initial continuous pressure of 200 mm Hg. Postoperatively, a systemic antibiosis was given according to antibiogram.

Results: 48–72 h after surgery an alteration from haemorrhagic to serous fluid was observed in the V.A.C.-canister. Afterwards, the pressure was decreased to 150 mm Hg and remained at this level till sponge removal. After a mean period of 9 [3–16] days the inflammation parameters have been retrogressive and the sponges were removed. An infection eradication could be achieved in 26/28 cases. In the two remaining cases the infected prosthesis had to be explanted and a gentamicin-vancomycin-loaded spacer has been implanted, respectively. At a total mean follow-up of 36 [12–87] months no reinfection or infection persistence was observed.

Discussion: The V.A.C.-system can be a valuable contribution in the treatment of early joint infections when properly used. Indications should be early infections with well-maintained soft-tissues for retention of the vacuum.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 583 - 583
1 Oct 2010
Anagnostakos K Kelm J Kristen A
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Introduction: The anterior tibial tendon rupture is an infrequent injury in the lower extremity. For prevention of misdiagnosis and further planing of surgical reconstruction exact knowledge of the foot anatomy and the tendon’s course are required.

Materials and Methods: We examined 27 formaldehyde-fixed cadavers (13 female-14 male) with a total of 53 feet (27 right, 26 left). 1 left leg was amputated. The skin and overlying fascia were removed to expose the anterior tibial muscle and tendon. The tendon was prepared along its entire course beneath the superior extensor retinaculum, special care was paid on osseous or tendinous abnormalities along its insertion into Os cuneiform mediale and Os metatarsal I. Photographs were then taken to document the pattern.

Results: 3 different insertion sites were noticed: in 36 feet the tendon inserted into the medial side of the cuneiform and the base of the first metatarsal bone and in 13 cases only into the medial side of the cuneiform bone. In the remaining 4 feet the tendon inserted into the cuneiform and the first metatarsal bone, but an additional tendon was noted taking its origin from the tibialis ant. tendon near its insertion into the os cuneiforme mediale and attaching to the proximal part of the metatarsal I.

Discussion: Knowledge of the anatomy in this region may be helpful primarily for diagnosis and subsequently for the interpretation of intraoperative findings and making the right choice for the most appropriate surgical procedure.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 75 - 75
1 Mar 2009
Anagnostakos K Hitzler P Pape D Kohn D Kelm J
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Implantation of antibiotic-loaded beads is accepted as an efficient option for local antibiotic therapy in orthopedic-related infections. However, recent reports have emphasized the bacteria growth persistence on antibiotic-impregnated bone cement. Hence, the aim of this study was to elaborate if bacterial adherence and growth could be determined on explanted gentamicin- and gentamicin-vancomycin-loaded beads after infection eradication. 18 chains of antibiotic-loaded beads (11 gentamicin-, 7 gentamicin-vancomycin-loaded) were examined. Indications for primary beads implantation included postoperative infections after total hip or knee arthroplasty, rotator cuff reconstruction, chronic foot osteomyelitis, anterior cruciate ligament reconstruction and dorsal spondylodesis. Among the isolated organisms, Staphylococcus epidermidis, Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA) were the most frequent ones. In 4 cases (3 × S. epidermidis, 1 × MRSA) bacteria growth persistence could be determined on the beads. S. epidermidis-strains persisted only on gentamicin-loaded beads, MRSA could grow on gentamicin-vancomycin-impregnated cement. In one case, the emergence of a gentamicin-resistant S. epidermidis-strain could be observed despite preoperative susceptibility. Bacteria growth persistence on bone cement is a hazardous problem in the orthopedic surgery and should therefore be born in mind. Adherence to cement can lead to emergence of bacteria resistance despite preoperative antibiotic susceptibility and might result in clinical recurrence of infection.