Introduction: External fixation has evolved from a mean to hold a bone in position to one that allows a gradual correction and lengthening. Platelet gel has been reported to be effective in enhancing osteogenesis. The association of these techniques could be effective in the treatment of pottraumatic bone loss fracture.

Materials and methods: Platelet gel has been obtained mixing 50 mL of autologous platelet concentrate to 2.5 mL of fibrin glue, produced from autologous FFP through CS-1 Cryoseal Thermogenesis.

Patient 1: Male, 39 years old, smoker, bearing tibial non-union with 17 cm bone loss has been treated by trifocal technique with platelet gel in the docking site procedure with autologous bone graft.

Patient 2: Male, 43 years old, smoker, suffering from exposed femoral fracture with sovracondilar bone loss, treated by acute shortening and proximal osteotomy in order to improve distractional ostogenesis according to Ilizarov method. Platelet gel had been positioned in the non-union sovracondilar site.

Results. Patient 1 has reached a good bone repair in the platelet gel application site within 4 months. Patient 2 has healed within 3 months.