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Orthopaedic Proceedings
Vol. 101-B, Issue SUPP_14 | Pages 53 - 53
1 Dec 2019
CLINICAL EVALUATION OF SYNOVIAL ALPHA DEFENSIN AND SYNOVIAL C-REACTIVE PROTEIN IN THE DIAGNOSIS OF PERIPROSTHETIC JOINT INFECTION
Stone W Gray CF Parvataneni HK Al-Rashid M Vlasak RG Prieto H
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Aim

Diagnosing periprosthetic joint infection after total joint arthroplasty is often challenging. The alpha defensin test has been recently reported as a promising diagnostic test for periprosthetic joint infection. The goal of this study was to determine the diagnostic accuracy of alpha defensin testing.

Method

One hundred and eighty-three synovial alpha defensin and synovial fluid C-reactive protein (CRP) tests performed in 183 patients undergoing evaluation for periprosthetic joint infection were reviewed. Results were compared with the Musculoskeletal Infection Society (MSIS) criteria for periprosthetic joint infection.

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