Aims. Impaction bone grafting with milled human allograft is the gold standard for replacing lost bone stock during revision hip surgery. Problems surrounding the use of allograft include cost, availability, disease transmission and stem subsidence (usually due to shear failure of the surrounding allograft). The aim of this study was to investigate various polymers for use as substitute allograft. The ideal graft would be a composite with similar mechanical characteristics as allograft, and with the ability to form de novo bone. Methods. High and low molecular weight (MW) forms of three different polymers (polylactic acid (PLA), poly (lactic co-glycolic) acid (PLGA) and polycaprolactone (PCL)) were milled, impacted into discs, and then tested in a custom built shear testing rig, and compared to allograft. A second stage of the experiment involved the addition of skeletal stem cells (SSC) to each of the milled polymers, impaction, 8 days incubation, and then tests for cell viability and number, via fluorostaining and biochemical (WST-1) assays. Results. The shear strengths of both high/low MW PLA, and high/low MW PLGA were significantly higher than those of milled allograft (P< 0.001, P< 0.001, P< 0.005 and P< 0.005) but high and low MW PCL was poor to impact, and had significantly lower shear strengths (P< 0.005, P< 0.001). Fluorostaining showed good cell survival on high MW PLA, high MW PCL and high MW PLGA. These findings were confirmed with WST-1 assays. Conclusions. High MW PLA as well as high MW PLGA performed well both in mechanical testing and cell compatibility studies. These two polymers are good contenders to produce a living composite for use as substitute human allograft in impaction bone grafting, and are currently being optimised for this use via the investigation of different production techniques and in-vivo studies

Aims. Disease transmission, availability and economic costs of allograft have resulted in significant efforts into finding an allograft alternative for use in impaction bone grafting (IBG). Biotechnology offers the combination of skeletal stem cells (SSC) with biodegradable polymers as a potential solution. Recently polymers have been identified with both structural strength and SSC compatibility that offer the potential for clinical translation. The aim of this study was to assess whether increasing the porosity of one such polymer via super critical CO. 2. fluid foaming (SCF) enhanced the mechanical and cellular compatibility characteristics for use as an osteogenic alternative to allograft in IBG. Methods. High molecular weight PLA scaffolds were produced via traditional (solid block) and SCF (porous) techniques, and the differences characterised using scanning electron microscopy (SEM). The polymers were milled, impacted, and mechanical comparison between traditional vs SCD created scaffolds and allograft controls was made using a custom shear testing rig, as well as a novel agitation test to assess cohesion. Cellular compatibility tests for cell number, viability and osteogenic differentiation using WST-1 assays, fluorostaining and ALP assays were determined following 14 day culture with SSC's. Results. SEM showed increased porosity of the SCF produced PLA scaffolds, with pores between 50–100µm. Shear testing showed the SCF polymer exceeded the shear strength of allograft controls (P< 0.001). Agitation testing showed greater cohesion between the particles of the SCF polymer (P< 0.05). Cellular studies showed increased cell number, viability and osteogenic differentiation on the SCF polymer compared to traditional polymer (P< 0.05) and allograft (P< 0.001). Conclusions. The use of supercritical C0. 2. to generate PLA scaffolds significantly improves the cellular compatibility and cohesion compared to traditional non-porous PLA, without substantial loss of mechanical shear strength. The improved characteristics are critical for clinical translation as a potential osteogenic composite for use in IBG

Introduction: Revision hip arthroplasty for aseptic loosening of femoral component is successfully treated with impaction bone grafting technique. Owing to easier technique and shorter operative time, distally fixed non-cemented long stems have gained popularity in the present era. However, use of long stems could make subsequent re-revision difficult due to further bone loss. The standard length stem has been often critiqued due to apprehension of peri-prosthetic fracture. This study aims to determine the long-term outcomes of the impaction bone grafting of the femur for aseptic loosening in revision hip arthroplasty using standard length C-stems. 168 total hip revisions of 162 patients with impaction bone grafting and cemented standard C-stem (done with standardized technique) between 1995 and 2008 at a tertiary referral centre were included. Revisions for infection and segmental bone defects were excluded. Mean follow-up of the 168 revision hips was 10.5 years (range 5 – 19.1 years). 14 patients (8.3%) were re-revised, reasons being, persistent deep infection (1.8%), repeated dislocations (1.2%), cup loosening (4.8%) and stem loosening (1.2%). Only 1 patient (0.6%) was re-revised due to stem loosening alone. No peri-prosthetic fractures (intra-operative or post-operative) or stem breakage were identified. Use of standard stem length in hip revisions with impaction bone grafting does not increase the risk of peri-prosthetic fractures, instead, reconstitutes the bone stock. This questions the conventional principle of bypassing the distal cavitation of femur by 2 cortical diameters with the use of long stem. In our experience, a good proximal femur support is key to performance of standard length cemented stems in revision for aseptic loosening irrespective of grade of distal cavitation for cavitatory defects of femur when treated with impaction bone grafting

Background. Ankle and hindfoot fusion in the presence of large bony defects represents a challenging problem. Treatment options include acute shortening and fusion or void filling with metal cages or structural allograft, which both have historically low union rates. Impaction grafting is an alternative option. Methods. A 2 centre retrospective review of consecutive series of 32 patients undergoing hindfoot fusions with impaction bone grafting of morselised femoral head allograft to fill large bony void defects was performed. Union was assessed clinically and with either plain radiography or weightbearing CT scanning. Indications included failed total ankle replacement (24 patients), talar osteonecrosis (6 patients) and fracture non-union (2 patients). Mean depth of the defect was 29 ±10.7 mm and mean maximal cross-sectional area was 15.9 ±5.8 cm. 2. Tibiotalocalcaneal (TTC) arthrodesis was performed in 24 patients, ankle arthrodesis in 7 patients and triple arthrodesis in 1 patient. Results. Mean age was 57 years (19–76 years). Mean follow-up of 22.8 ±8.3 months. 22% were smokers. There were 4 tibiotalar non-unions (12.5%), two of which were symptomatic. 10 TTC arthrodesis patients united at the tibiotalar joint but not at the subtalar joint (31.3%), but only two of these were symptomatic. The combined symptomatic non-union rate was 12.5%. Mean time to union was 9.6 ±5.9 months. One subtalar non-union patient underwent re-operation at 78 months post-operatively after failure of metalwork. Two (13%) patients developed a stress fracture above the metalwork that healed with non-operative measures. There was no bone graft collapse with all patients maintaining bone length. Conclusion. Impaction of morselised femoral head allograft can be used to fill large bony voids around the ankle and hindfoot when undertaking arthrodesis, with rapid graft incorporation and no graft collapse despite early loading. This technique offers satisfactory union outcomes without the need for shortening or synthetic cages

The choice of stem length in total hip revision with impaction bone grafting of femur is essentially based upon the grade of cavitation of femur and surgeon's preference. The standard length stem has been often critiqued for the apprehension of peri-prosthetic fracture. Our study highlights the importance of proximal bone stock rather than distal cavitation in determining the length of femoral stem. 168 total hip revisions of 162 patients with impaction bone grafting and cemented standard C-stem (done with standardized technique) between 1995 and 2008 at a tertiary referral centre were included. Revisions for infection and segmental bone defects were excluded. Serial radiographs were retrospectively analysed by two people independently, using Endoklinik classification, Gruen zones and more and outcomes were analysed. Mean follow-up of the 168 revision hips was 10.5 years (range 5 – 19.1 years). 14 patients (8.3%) were re-revised, reasons being, persistent deep infection (1.8%), repeated dislocations (1.2%), cup loosening (4.8%) and stem loosening (1.2%). Only 1 patient (0.6%) was re-revised due to stem loosening alone. No peri-prosthetic fractures or stem breakage were identified. Use of standard stem length in hip revisions with impaction bone grafting doesn't increase the risk of peri-prosthetic fractures even during long term follow up period. This questions the principle of bypassing the distal cavitation of femur by 2 cortical diameters with the use of long stem. In our experience, a good proximal femur support aids in the performance of standard length cemented stems in revision for aseptic loosening irrespective of grade of distal cavitation for cavitory defects of femur treated with impaction bone grafting

Principles of bone preservation and restoration of biomechanical alignment should be followed during revision total hip arthroplasty (THA). Where possible, conservative femoral revision techniques and even reconstructive de-escalation involving using primary stems should be considered. This study aims to investigate the outcome of patients who have undergone conservative femoral revision THA in our Institution. We retrospectively identified patients from our Institution's revision arthroplasty database who had cemented, or un-cemented primary stems implanted during revision THA of a previous stemmed femoral implant. Our primary outcome measure was all-cause re-revision THA with a secondary outcome measure of improvement in Oxford hip score (OHS). Radiographic evidence of stem loosening and post-op complications were recorded. Between 02/12/2014 to 12/12/2019, there were 226 patients identified with a mean follow up of 2 years (1–5 years). The majority of cases were represented by Paprosky type 1 (63%) and type 2 (25%) femoral defects. There were 45 patients (20%) who underwent impaction bone grafting (IBG) and 43 patients (19%) who had a cement in cement (CinC) femoral revision and cemented primary stem in 137 (60%), 1 uncemented stem with no IBG or CinC revision. Kaplan Meier survival for all-cause re-revision THA was 93.7% (95% CI: 88.3 – 100) at 3 years. The reasons for re-revision included 4 periprosthetic fractures, 4 dislocations, 1 deep infection, 1 loosening of femoral component and 1 loosening of acetabular component. Pre- and post-operative OHS scores were available in 137 hips (60%) with a mean improvement of 13. Radiographic review revealed 7% of cases with evidence of loosening in 1 or more Gruen zones. Our early results support the use of conservative femoral revision THA techniques where appropriate, with low complication and re-revision rates. Revisions using primary femoral components, where appropriate, should be considered in surgical planning to avoid unnecessary reconstructive escalation

Trabecular metal (TM) augments are designed to support an uncemented socket in revision surgery when adequate rim fit is not possible. We have used TM augments in an alternative arrangement, to contain segmental defects to facilitate impaction bone grafting (IBG) and cementation of a cemented socket. However, there is a paucity of literature supporting the use of this technique. We present one of the largest studies to date, reporting early outcomes of patients from a tertiary centre. A single-centre retrospective analytical study of prospectively collected data was performed on patients who had undergone complex acetabular reconstruction using TM augments, IBG and a cemented cup. All patients operated between 2015 and 2019 were included. We identified 105 patients with a mean age of 74yrs. The mean follow-up was 2.3 years(1–5.5yrs). Our primary outcome measure was all-cause revision of the construct. The secondary outcome measures were, Oxford hip score (OHS), radiographic evidence of cup migration/loosening and post-op complications. Eighty-four out of 105 patients belonged to Paprosky grade IIb, IIc or IIIa. Kaplan-Meier survivorship for all-cause revision was 96.36% (CI, 90.58–100.00) at 2 years with 3 failures. Two were due to early infection which required two-stage re-revision. The third was due to post-operative acetabular fracture which was then re-revised with TM augment, bone graft and large uncemented cup. Pre-op and post-op matched OHS scores were available for 60 hips(57%) with a mean improvement of 13 points. Radiographic analysis showed graft incorporation in all cases with no evidence of cup loosening. The mean vertical cup migration was 0.5mm (Range −5 to 7mm). No other complications were recorded. This study shows that reconstruction of large acetabular defects during revision THA using a combination of TM augments to contain the acetabulum along with IBG to preserve the bone stock and a cemented socket is a reliable and safe technique with low revision rates and satisfactory clinical and radiographic results. Long term studies are needed to assess the possibility of preservation and regeneration of bone stock

Total hip arthroplasty (THA) in patients under 30 years remains a challenge. The long-term survival data are often disappointing. In our institution, we have always used cemented components in all patients under 30 years, combined with acetabular impaction bone grafting (IBG), if necessary. We reviewed 139 consecutive patients (180 hips) treated between 1986 to 2014. Mean age at time of surgery was 24 (13–30.0) years. Acetabular IBG was applied in 127 (71%) cases. AAOS cavitary defect was seen in 26 (14%) cases, a AAOS segmental defect in 51 (28%) and a combination in 17 (9%). The mean preoperative HHS improved from 47 (20–81) to 87 (28–100) at review. During follow-up 26 hips have been revised (23 cups and 11 stems). Indications for revision were aseptic loosening (n=15), septic loosening (n=5), recurrent dislocation (n=3), wear (n=1), and stem fracture (n=1). The 10-year Kaplan-Meier survival of any component with endpoint revision for any reason was 87% (95% CI 79%–92%) and for aseptic loosening 92% (84%–96%). The 15-year survival of any component with revision for any reason as the endpoint was 77% (65%–86%) and for aseptic loosening 84% (71%–92%). Cemented THA and, if needed with impaction bone grafting, in patients under 30 years provides satisfying long-term results up to 15 years after surgery. Probably this biological approach with IBG may facilitate the inevitable revisions in the future in these young patients because of more bone stock

Aims: Irradiated allograft bone may help to reduce the risk of transmission of infectious agents from donor to recipient. The purpose of this study was to establish the results of impaction bone grafting of acetabular defects with froze, irradiated allograft bone. Methods: All patients treated by a single surgeon with impaction bone grafting of acetabular defects at revision total hip replacement were reviewed retrospectively. All operations were performed during the period 1994–2000. The mean follow-up was 50 months (range 30–96 months). Case notes and X rays were reviewed and analysed. The Paprosky grade of acetabular defects was determined from the pre-operative X rays and the surgeonñs operation note. Post-operative X rays were reviewed to establish the extent and rate of new bone in-growth. Functional outcomes were determined by way of self-administered questionnaires. Results: Complete records and X rays were obtained for 33 patients who underwent revision hip arthroplasty with impaction bone grafting of the acetabulum using frozen, irradiated allograft bone. There were no complications associated with the bone grafts and no patient required a re-operation. Review of serial X rays conþrmed in-growth of host bone and the functional outcome was satisfactory. Overall 29 patients (88%) declared themselves satis-þed with the outcome of their operation and 32 patients (97%) improved functionally after the operation. Conclusions: These results indicate that satisfactory results can be achieved with impaction bone grafting using frozen, irradiated allograft bone. The use of irradiated bone graft can potentially reduce the risk of disease transmission from donor to recipient without compromising the surgical results

Though over ten-year follow-up results of impaction bone grafting for acetabular reconstruction from European countries are available in literatures, clinical reports from Asian countries are rare. The purpose of the present study is to assess mid-term clinical and radiographic follow-up results at least three years after acetabular reconstruction with impaction bone grafting technique by single surgeon in Japanese cohort. The senior author performed 24 acetabular revisions with impaction bone grafting technique in 24 patients from February 2001 to June 2005. The average age of the patients at the revision was 67.5 years (36–82 years). The average follow-up period was 5 years and 5 months (3–7.3 years). The reasons for the operation were aseptic loosening of sockets in 17 hips and migration of bipolar heads in seven. The acetabular bone defects were classified as cavitary in 3 hips and as combined segmental-cavitary in 21 hips according to AAOS classification. For clinical assessment, Merle d’Aubigné and Postel hip score was assessed. Peri-operative complications were recorded. For radiological assessment, antero-posterior hip radiograph was analyzed pre-operatively, and post-operatively at one month, 6 months and every 6 months thereafter. Clear lines more than 2 mm around the sockets using DeLee and Charnley zone classification, and migration of the sockets were assessed. Hodgikinson’s type 3 (complete demarcation line) and type 4 (migration more than 5 mm or change of the angle more than 5 degrees) were classified as “loosening”. Kaplan-Meier survival analysis was performed with radiographic loosening and any re-operation (including recommendation for the re-operation) for the sockets as the end point, respectively. The mean Merle d’Aubigné and Postel hip score improved from 11.5 points before operation to 15.7 points at the final follow-up. Though, intra-operative blow-out fracture of the acetabular floor was detected in 3 hips, re-containment had been achieved by adding metal mesh or bone graft. Clear lines at cement-bone interface were detected at zone 3 in 2 hips. Migration more than 5 mm was detected in 2 hips of type III defect at 2 years and 6 months. Re-revision was recommended for one migrated hip at 3 years and 6 months after the operation, and the other hip was stable with no clinical symptom without progressive migration at the final follow-up of 5 years. The Kaplan-Meier survival analysis, with loosening and re-operation as the end point, predicted a rate of survival of the socket of 91.7% and 95.2% at 5 years, respectively. In conclusion, acetabular reconstruction with impaction bone grafting is attractive, but technical demanding procedure. The survival rate of the present series was compatible with the results of previous literatures. However, careful follow-up is essential, especially for the cases with massive bone defect

Irradiated allograft bone may help to reduce the risk of transmission of infectious agents from donor to recipient. The purpose of this study was to establish the results of impaction bone grafting of acetabular defects using irradiated allograft bone. Patients treated with impaction bone grafting of ace-tabular defects between 1994 and 2000 were reviewed retrospectively. The mean follow-up was 50months (range 30–96months). Case notes and Xrays were reviewed and analysed. The Paprosky grade of acetabular defects was determined. Functional outcomes were determined by way of self-administered questionnaires. Complete records and Xrays were obtained for 33 patients who underwent impaction bone grafting of the acetabulum using freeze-dried, irradiated bone. The Paprosky classifications of the defects were as follows: 3 type 1, 10 type 2A, 4 type 2B, 4 type 2C, 10 type 3A and 2 type 3B. There were no complications associated with the bone grafts and no patient required reoperation. Review of serial Xrays confirmed ingrowth of host bone. The functional results obtained were as follows: 17 patients (52%) could walk an unlimited distance. 11 patients (33%) required no walking aids whilst a further 17 (52%) required a single cane to mobilise. 21 patients (64%) were able to use public transport after the operation. 20 patients (61%) reported little or no pain. 9 patients (28%) had no limp and 14 patients (42%) had a slight limp. Overall 29 patients (88%) declared themselves to be satisfied with the outcome of their surgery. 32 patients (97%) improved functionally after their operation. These results indicate that satisfactory results can be achieved with impaction bone grafting using irradiated, frozen allograft bone. The use of irradiated bone graft can potentially reduce the risks of disease transmission from donor to recipient without compromising the surgical results

Femoral impaction bone grafting (IBG) may be used to restore bone stock in revision total hip arthroplasty (THA) and allow use of a shorter, than otherwise, length prosthesis. This is most beneficial in young patients who are more likely to require further revision surgery. This study aimed to assess the results of femoral IBG for staged revision THA for infection. A prospective cohort of 29 patients who underwent staged revision THA for infection with femoral IBG and a cemented polished double-tapered (CPDT) stem at the final reconstruction was investigated. The minimum follow-up was two years (2 – 10 years, median 6 years). Stem subsidence was measured with radiostereometric analysis. Clinical outcomes were assessed with the Harris Hip, Harris Pain, and and Société Internationale de Chirurgie Orthopédique et de Traumatologie Activity (SICOT) Scores. The original infection was eradicated in 28 patients. One patient required a repeat staged revision due to re-infection with the same organism. At two-year follow-up, the median subsidence at the stem-bone interface was −1.70 mm (−0.31 to −4.98mm). The median Harris Hip Score improved from 51 pre-operatively to 80 at two years (p=0.000), the Harris Pain Score from 20 to 44 (p=0.000) and the SICOT Score from 2.5 to 3 (p=0.003). As successful eradication of infection was achieved in the majority of patients and the stem migration was similar to that of a primary CPDT stem, this study supports the use of femoral IBG during the final reconstruction of the femur after staged revision THA for infection

Introduction and Aims: We undertook this study to detemine the results of acetabular fixation using the Duraloc 300 uncemented acetabular component combined with impaction bone grafting in patients with acetabular protrusion. Method: Thirty consecutive total hip replacements using a Duraloc 300 cup in patients with acetabular protrusion requiring impaction bone grafting were reviewed at an average of 5.2 years. Pre-operative x-rays were analysed for degree of protrusion. Post-operative x-rays were analysed for cup placement and interface gaps. Follow-up films were analysed for graft incorporation, lucent lines, osteolysis, wear and migration. Kaplan-Meier survivorship analysis was performed. Results: All components were found to be stable with no evidence of loosening or migration. All but two cases showed trabeculated bone with an average minimum thickness of 7mm of bone medial to the cup in zone 2. Mean rate of wear was 0.10mm per year. No cases of pelvic osteolysis were seen. Conclusion: The Duraloc 300 cup provides excellent fixation in patients with acetabular protrusion and impaction bone grafting. The graft has been found to incorporate and remodel. We are therefore optimistic that the durability of fixation should equal that of primary hip surgery without protrusion

Significant proximal femoral bone deficiency in revision hip surgery poses a considerable challenge, especially as revision hip surgery is increasing in prevalence. Many femoral prosthetic devices, which compensate for this bone loss, are available to surgeons but ideally one wants to restore viable proximal bone stock. The Oxford Universal Hip (OUH) has been designed and modified with these challenges in mind. This is atrimodular, non-locking device that allows for some rotation and subsidence in the cement. Load transfer occurs at the proximal wedge, thus avoiding proximal stress shielding. The OUH has been used extensively in both primary and revision hip surgery and is particularly useful when used in conjunction with proximal impaction bone grafting. The main aim of this study was to determine the clinical outcome of the patients. The viability and survivorship of the impacted bone graft was assessed in order to give some indication of adequate perfusion of the incorporated bone grafting. Between 1999 and 2002 the OUH, in combination with proximal impaction bone grafting, was implanted in 72 hip revisions in 69 patients. All patients were clinically evaluated using the Oxford Hip score. Histological samples of impacted bone grafting were analysed by a pathologist 2 years after implantation to assess viability and perfusion of the impacted bone graft. The Oxford Hip Score improved from a pre-operative to a post-operative score of 45 (26–58) to 24.3 (12–43) respectively (p< 0.001). The mean follow up time was 32.7 months and in that time there were no re-revisions for aseptic loosening. Histology demonstrated viable bone stock in the proximal femur where bone grafting had been impacted 2 years previously. The OUH is a versatile hip prosthesis for use in revision hip arthroplasty and is especially well suited to proximal impaction bone grafting where it is possible to restore viable bone stock

Introduction: During femoral impaction bone grafting high forces and hoop strains may be generated with subsequent risk of fracture. Vibration is commonly used in civil engineering applications to increase aggregate compressive and shear strengths. We hypothesized that the use of vibration during impaction bone grafting, reduces the maximum hoop strains, and hence risk of fracture, and improves particle interlocking, producing a stronger aggregate. Method: A series of femoral impaction bone graftings on physiological composite femurs, using morsellised graft from fresh frozen human femoral heads were performed. The standard Exeter impaction technique was used in the control group and vibration assisted compaction used in the study group. Total force imparted, hoop strains and subsidence rate were measured. Results: Significantly more allograft was used in the vibration group than in the control group (73.1g, 79.5g, p=0.01). Higher mean peak loads were produced during proximal compaction in the control group (3.28kN) than in the vibration group (1.71kN, p=0.005). Higher mean peak and mid proximal hoop strains were generated in the control group (13.2%, 5.6%) compared to the vibration group (4.2%, 2.7% p=0.009, p=0.006). The mean total axial subsidence after 50,000 cycles was significantly less in the control group (2.47mm, SD 0.55) compared to the vibration group (1.79mm, SD 0.30, p=0.03). Discussion: The use of vibration leads to reduced peak loads and hoop strains in the femur during graft compaction which may reduce the risk of femoral fracture. Additionally the resulting graft is better able to resist subsidence thus conferring improved mechanical stability. A safer, more flexible method to compact bone graft could lead to the more widespread use of IBG in revision hip surgery

Introduction. Impaction bone grafting for reconstitution of acetabular bone stock in revision hip surgery has been used for nearly 30 years. We report results in a group of patients upon whom data has been collected prospectively with a minimum ten year follow-up. Material and Methods. Acetabular impaction grafting was performed in 305 hips in 293 patients revised for aseptic loosening between 1995 and 2001. In this series 33% of cases required stainless steel meshes to reconstruct medial wall or rim defects prior to graft impaction. These meshes were the the only implants used for this purpose in this series. All Paprosky grades of defect were included. Clinical and radiographic outcomes were collected in surviving patients at a minimum of 10 years following the index operation; mean follow-up was 12.4 years (SD 1.5; range 10.0–16.0). Results. Kaplan-Meier survivorship with revision for aseptic loosening as the endpoint was 86% (95% CI 81.1 to 90.9%). Clinical scores for pain relief and function remained satisfactory (mean OHS 33.3, Harris hip score for pain 36.7, Harris hip score for function 27.3). Of the 125 hips still available with at least 10 years of radiographic follow-up, 97 appeared stable and 28 were judged to be radiologically loose; however, there was no significant difference in the pain and function scores between the two groups. The overall complication rate was 11.5%, including 1% peri-operative death, 3.3% dislocation and 0.3% deep infection. Discussion. This is the largest series of medium- to long-term results of acetabular impaction bone grafting with a cemented cup for revision hip arthroplasty reported to date. The technique is particularly successful when used for Paprosky grade 1 and 2 deficiencies; grade 3 deficiencies may be better managed with a different method for reconstructing larger defects e.g. trabecular metal augments. Conclusion. This series shows good long-term results for impaction bone grafting of acetabular deficiencies in revision hip surgery, with survivorship of 86% for aseptic loosening at 13.5 years and satisfactory clinical outcomes

Introduction. Acetabular bone deficiency, especially proximal and lateral deficiency, is a difficult technical problem during primary total hip arthroplasty (THA) in developmental hip dysplasia (DDH). We report a configuration-based acetabular classification, a modification of the Crowe's classification, of DDH, including a definition of shallow acetabuli. We also report a new reconstruction method using a medial reduced cemented socket andadditional bulk bone in conjunction with impaction morselized bone grafting (Ad-BBG method). We aimed to evaluate usefulness of the classification and the method's clinical/radiographic outcomes. Methods. One hundred thirty one hips of 330 THAs for DDH (40%) were defined shallow. The Ad-BBG methodwas performed on 102 hips (78% shallow hips). For the 24 remaining hips, THA was performed using the conventional interposition bulk bone grafting (Ip-BBG) (8 hips)or without bone grafting by using rigid lateral osteophyte (16 hips). Japanese Orthopaedic Association (JOA) scores and the Merle d'Aubigne and Postel (M&P) scores were used in follow-up; radiographs were analyzed retrospectively. The criteria used for determining loosening were migration or a total radiolucent zone between the prosthesis/bone cement and host bone. The follow-up period was 9.2 ± 2.6 (range, 5.0–14.0) years. Operative Technique. Theresected femoral head was sectioned at 1–2-cm thickness, and a suitable size of the bulk bone graft was placed on the lateral iliac cortex and fixed by polylactate absorbable screws. Autogenous impaction morselized bone grafting, with or without hydroxyapatite granules, was performed along with the implantation of medial reduced cemented prosthetic hip socket. The same surgical team performed all surgical procedures. Results. Acetabular component was revised in only one case with a shallow and Crowe Type IV acetabulum. The mean JOA and M&P scores improved from preoperative 39.3 and 6.8 points to postoperative 93.9 and 17.2 points, respectively. Within 2 years postoperatively, most Ad-BBGs cases showed successful bone remodeling and bone graft reorientation on radiographs. Conclusions. We had good results of acetabular reconstruction in primary THA using the medial reduced cemented socket and bone grafting methods including the Ad-BBG technique in conjunction with impaction morselized bone grafting for shallow dysplastic hip. Osteointegration and good clinical outcomes were achieved in most cases. However, long-term outcomes should be subject of further investigation. Summary. Reconstruction methods for shallow dysplastic hip using medial reduced cemented socket and additional bulk bone grafting in conjunction with impaction morselized bone grafting are presented

Introduction. Biological repair of acetabular bone defects after impaction bone grafting (IBG) in total hip arthroplasty could facilitate future re-revisions in case of failure of the reconstruction again using the same technique. Few studies have analysed the outcome of these acetabular re-revisions. Patients and Methods. We analysed 34 consecutive acetabular re-revisions that repeated IBG and a cemented cup in a cohort of 330 acetabular IBG revisions. Fresh-frozen femoral head allografts were morselized manually. All data were prospectively collected. Kaplan-Meier survivorship analysis was performed. The mean follow-up after re-revision was 7.2 years (2–17). Intraoperative bone defect had lessened after the first failed revision. At the first revision there were 14 hips with Paprosky 3A and 20 with Paprosky type 3B. At the re-revision there were 5 hips with Paproky 2B, 21 with Paprosky type 3A and 8 with type 3B. Lateral mesh was used in 19 hips. Results. The mean Harris Hip Score improved from 45.4 (6.7) to 77.1 (15.6) at final follow-up. The radiological analysis showed cup migration in 11 hips. The mean appearance time was 25 months (3–72). Of these, migration in three cups was progressive and painful requiring re-revision. Cup tilt was found in all migrated hips. There were one dislocation requiring a cemented dual mobility cup associated with IBG and one infection resolved with resection-arthroplasty. Survival with further cup revision for aseptic loosening was 80.7% (95% Confidence Interval 57.4–100) at 11 years. In all surviving re-revisions trabecular incorporation was observed without radiolucent lines. Conclusion. Biological repair can be obtained by restoring the bone stock, even after successive acetabular reconstructions using IBG and a cemented cup

Bone grafts are a useful option to treat large posteromedial defects in tibia which are usually seen in medial condyle of the tibia in severe varus knees and lateral condyle in valgus knees. Contained defects can be treated using cancellous bone chips/graft. Uncontained peripheral defects may be treated using cement with or without screw augmentation for small defects. Large defects > 25 % of tibial plateau and > 5 mm deep may need structural bone graft or impaction bone grafting or metal wedges. The use of bone grafts is a viable alternative for the treatment of massive bone loss. For stable fixation of the components, we performed osseous reconstruction of tibial condyle using autologous structural bone grafts /impaction bone grafting. We used structural bone graft for 62 tibial defects in severe varus knees in 675 primary TKR. Grafts originating from the femoral condyles were fixed with screws. Morselised autograft supported by mesh, fixed with screws, were used in 8 patients. Bilateral bone grafting was done in 28 patients. Goal was to obtain firm seating of the tibial tray on a rim of viable bone along with rigid press fixation of the medullary stem. We observed an average 70-point postoperative increase in knee function according to HSS score. Graft incorporation was seen in all patients at average seven year follow-up. Autologous bone grafts can be successfully used for reconstruction of large osseous defects. It is available then and there, is biological and cost effective

Introduction. Various methods to manage medial tibial defects in primary total knee arthroplasty (TKA) have been described. According to Vail TP, metal augmentation is usually indicated for defect depth of >10 mm of the medial tibial plateau. The outcomes of metal augmentation have been described as excellent. Nevertheless, we believe that it is mandatory to preserve as much of the bone as possible for future revision surgeries. Therefore, we performed autologous impaction bone grafting even for large bone defects (defect depth of ≥10 mm) in primary TKA. The objectives of this study are to describe our bone grafting technique in detail and to assess the radiological outcomes of the grafted bone. Methods. Between 2003 and 2011, 26 TKAs with autologous impaction bone grafting for ≥10 mm medial tibial defects were performed. The preoperative diagnoses were osteoarthritis in 17 knees, rheumatoid arthritis in 2 knees, osteonecrosis of the medial tibial condyle in 6 knees, and Charcot's joint in 1 knee. The average mediolateral width and depth of the medial tibial defects, measured after the horizontal osteotomy of the tibial articular surface, were 17.8 mm (range, 10–25 mm) and 12.0 mm (range, 10–23 mm), respectively. The average patient age at surgery was 73.2 years (range, 56–85 years). The patients were followed up for an average of 55 months (range 27–109 months). Bone grafting technique: Multiple drill holes (white arrow) were made on the floor of the defect (A) and a morselized cancellous bone was impacted using the grip end of a metal hammer (white asterisk) and firm manual pressure to fill the defect. Thus, the firm impaction prevented bone cement from entering the space between the graft and the tibial host bed. An assistant's index finger (black asterisk) was used as a bank (B). The tibial component was fixed on the grafted bone (white asterisk) with bone cement (C). Internal fixation devices were not required, and stem extension was used in only Charcot's joint (defect depth=23 mm). Aftertreatment was the same as that for the usual TKAs without bone defects. Results. In terms of clinical outcomes, no patient showed disturbances in walking ability at final follow-up. The average knee flexion angle was 114° (range, 95°–130°). The grafted bone was kept at the grafted area on the radiograms throughout the follow-up period. No absorption or collapse of the grafted bone was observed on the radiograms at the final follow-up. Usually, the grafted bone showed osteosclerotic changes around 2–3 months after TKA. Then, the osteosclerosis became weakened and the bony trabeculae could be detected in the grafted area. Finally, the grafted bone completely incorporated into the host bone in all knees with evidence of bony trabeculae crossing the interface by up to 1 year after surgery. The margin of the grafted area resembled bony cortex in 19 TKAs (73.1%). Conclusions. Our technique is easy, economic, and reproducible. It is an acceptable alternative to metal augmentation for large medial tibial defects in primary TKA