Aims

To map the Oxford Knee Score (OKS) and High Activity Arthroplasty Score (HAAS) items to a common scale, and to investigate the psychometric properties of this new scale for the measurement of knee health.

We sought to evaluate the early post-operative active range-of-motion (AROM) between robotic-assisted total knee arthroplasty (raTKA) and conventional TKA (cTKA). A secondary data analysis on a global prospective cohort study was performed. A propensity score method was used to select a matched control of cTKA from the same database using 1:1 ratio, based on age, sex, BMI, and comorbidity index. This resulted in 216 raTKA and cTKA matched cases. Multivariable longitudinal regression was used to evaluate difference in ROM over time and values are reported as least squares means (95% confidence interval). The longitudinal model tested the treatment effect (raTKA vs cTKA), time effect, and their interaction with control on covariance of patients ‘s age, sex, BMI, comorbidity and pre-operative flexion. Logistic regression was used to analyze the active flexion level at one month (cut by 90°) and three months (cut by 110°). At one-month postoperative the raTKA cases had more AROM for flexion by an average of 5.54 degrees (p<0.001). There was no difference at three months (p=0.228). The raTKA group had a greater improvement from pre-operative values at both one-month, with an average 7.07° (3.6°, 10.5°, p<0.001) more improvement, and at three-months with an average improvement of 4° more (1.61°, 7.24°, p=0.0115). AROM for extension was lower overall in the raTKA group by an average of 0.44° (p=0.029). The raTKA patients had higher odds of achieving ≥90° of flexion at one-month (OR 2.15, 95% CI 1.16, 3.99). raTKA resulted in greater AROM flexion gains in the early postoperative period than cTKA. Additional research is needed to understand if these earlier gains in AROM are associated with improved patient satisfaction and continued improvements with time

Treatment of bone infection often includes a burdensome two-stage revision. After debridement, contaminated implants are removed and replaced with a non-absorbable cement spacer loaded with antibiotics. Weeks later, the spacer is exchanged with a bone graft aiding bone healing. However, even with this two-stage approach infection persists. In this study, we investigated whether a novel 3D-printed, antibiotic-loaded, osteoinductive calcium phosphate scaffold (CPS) is effective in single-stage revision of an infected non-union with segmental bone loss in rabbits. A 5 mm defect was created in the radius of female New Zealand White rabbits. The bone fragment was replaced, stabilized with cerclage wire and inoculated with Staphylococcus aureus (MSSA). After 4 weeks, the infected bone fragment was removed, the site debrided and a spacer implanted. Depending on group allocation, rabbits received: 1) PMMA spacer with gentamycin; 2) CPS loaded with rifampin and vancomycin and 3) Non-loaded CPS. These groups received systemic cefazolin for 4 weeks after revision. Group 4 received a loaded CPS without any adjunctive systemic therapy (n=12 group1-3, n=11 group 4). All animals were euthanized 8 weeks after revision and assessed by quantitative bacteriology or histology. Covariance analysis (ANCOVA) and multiple regression were performed. All animals were culture positive at revision surgery. Half of the animals in all groups had eliminated the infection by end of study. In a historical control group with empty defect and no systemic antibiotic treatment, all animals were infected at euthanasia. There was no significant difference in CFU counts between groups at euthanasia. Our results show that treating an osteomyelitis with segmental bone loss either with CPS or PMMA has a similar cure rate of infection. However, by not requiring a second surgery, the use of CPS may offer advantages over non-resorbable equivalents such as PMMA

Introduction. Many groups consider passive flexion to be a good indicator of postoperative success, to the point where this outcome directly influences certain outcome scores such as Knee Society Scores (KSS). However, it is alternatively believed that normal-like kinematics result in better TKA outcomes, and previous fluoroscopy studies have demonstrated that there are many parameters that affect weight-bearing range-of-motion. The objective of this study to investigate the correlations between patient-reported outcomes, passive flexion, and weight-bearing knee kinematics. Methods. The femorotibial kinematics, passive and weight-bearing range-of-motion, and KOOS and KSS for 291 TKA subjects were collected in a retrospective study. The average age, BMI, and post-op time was 69.2±7.2 years, 29.3±4.6, and 22.4±16.3 months, respectively. Pearson correlation analysis was used to find the statistical correlations between the various parameters, and two-tailed t-tests were carried out to find statistical differences. Results. Superior weight-bearing flexion was statistically correlated with both higher KOOS (r=0.2122, p=0.0094) and KSS (r=0.2986, p<.0001), shown in Table 1. Interestingly, there was no correlation with respect to passive flexion and KOOS (r=0.1363, p=0.0975). Correlations between KSS and passive flexion were not analyzed due to the inherent covariance between these parameters. Furthermore, subjects with paradoxical anterior sliding of either condyle had significantly lower KSS scores than those without anterior sliding (81.1±11.9 versus 84.4±12.4 for lateral, p=0.03, and 82.2±12.1 versus 85.1±12.5 for medial, p=0.02). Conclusion. The results of this study revealed that weight-bearing flexion and not passive flexion is a better predictor of TKA outcomes. Subjects having greater weight-bearing flexion demonstrated higher KOOS and KSS scores. Also, subjects that experienced a paradoxical anterior slide had a statistically lower KSS than those subjects that experienced posterior femoral rollback. Therefore, it may be more important to evaluate weight-bearing flexion during clinical exams. For any figures or tables, please contact the authors directly

Introduction. Wearable sensors are promising tools for fast clinical gait evaluations in individuals with osteoarthritis (OA) of the knee and hip. However, gait assessments with wearable sensor are often limited to relatively simple straight-ahead walking paradigms. Parameters reflecting more complex and relevant aspects of gait, including dual-tasking, turning, and compensatory upper body motion are often overlooked in literature. The aim of this study was to investigate turning, dual-task performance, and upper body motion in individuals with knee or hip OA in addition to spatiotemporal gait parameters, taking shared covariance between gait parameters into account. Methods. Gait was compared between individuals with unilateral knee (n=25) or hip (n=26) OA scheduled for joint replacement, and healthy controls (n=27). For 2 minutes, subjects walked back-and-forth a 6 meter trajectory making 180 degree turns, with and without a secondary cognitive task. Gait parameters were collected using four inertial measurement units on feet, waist, and trunk. To test if turning, dual-tasking, and upper body motion had added value above common spatiotemporal parameters, a factor analysis was conducted. Standardized mean differences were computed for the comparison between knee or hip OA and healthy controls. One gait parameter was selected per gait domain based on factor loading and effect size for the comparison between OA groups and healthy controls. Results. Four independent domains of gait were obtained: speed-spatial, speed-temporal, dual task cost, and upper body motion. Turning parameters were part of the speed-temporal domain. From the gait domains that were obtained, stride length (speed-spatial) and cadence (speed-temporal) had the strongest factor loadings and effect sizes for both knee and hip OA, and lumbar sagittal range of motion (upper body motion) for hip OA only. Although dual-task cost was an independent domain, it was not sensitive to knee or hip OA. Conclusions. Stride length, cadence, and lumbar sagittal range of motion were non-redundant and sensitive gait parameters, representing (compensatory) gait adaptations in individuals with knee or hip OA. Turning or dual-task parameters had limited additional value for evaluating gait in knee and hip OA, although dual-task cost constituted a separate gait domain. These findings hold promise for objective gait assessments in the clinic using wearable sensors. Future steps should include testing responsiveness of these gait domains to interventions aiming to improve mobility, including knee and hip arthroplasty

Purpose of the study: Grafting the anterior cruciate ligament with a bone-tendon-bone free transplant injures the harvesting site, causing sensorial disorders by injuring the infrapatellar nerve in 70% of the cases. Mini-invasive techniques can limit these complications. The purpose of this work was to analyse the feasibility of a mini-invasive technique using a single incision. Material and methods: A prospective comparative study was conducted in our unit to compare a group of “classical” harvesting via an anteromedial incision and a “mini-invasive” technique using a incision centred on the patella with the graft being harvested with a specially designed harvesting instrument. Each group was composed of 20 patients. The patients were reviewed six to eight months postoperatively. Clinical assessment (IKDC, Lillois score, analysis of sensorial impairment) was associated with the radiographic and ultrasound analysis. Radiographic laxity was assessed on the stress views at 15 kg. The ultrasound study analysed the patellar tendon and the peritendon. Significance for statistical tests was set at 0.05 with correlation coefficients (R) determined with a covariance matrix ½ Log([1 + R]/[1−R]). Results: The grafts harvested by the classical method presented good characteristics in all cases whereas this was true for only 45% of the mini-invasive grafts. Anterior pain was noted in 22% of patients in the classical group and in 33 of the mini-invasive group. There was no correlation between anterior knee pain and knee walking or thickness of the peritendon. A correlation was found between knee walking and asymmetry of the patellar tendon thickness in the mini-invasive group. The subjective IKDC score was the same in the two groups and the IKDC objective score was not significantly different (94% (A or B) in the classic group and 81% (A or B) in the mini-invasive group. Conclusion: This mini-invasive technique with a single incision respects the infrapatellar branches of the medial saphenous nerve in 95% of the cases. But the quality of the graft is less satisfactory than with the classical harvesting technique. A correlation was found between the form of the anterior tibial tubercle which could be used to better define the ideal indication for this technique which remains a difficult procedure

Purpose of the study: The form of the anterior tibial tuberosity (ATT) has not been described in anatomy studies. Insertion of the patellar tendon can, by its form, modify the lever arm of the extensor system and induce pathological conditions having an impact on the form of the apex or tip of the patella. The purpose of this work was to analyse the types of tibial tuberosities observed on the radiographs of 50 patients. Material and method: Fifty patients were included in this prospective study. The form of the ATT was defined by two angles. These angles were measured on the strictly lateral x-ray. The ATT-shaft angle (ATT-d) was defined by the intersection between the anatomic axis of the tibial diaphysis and the anterior cortical of the ATT which corresponds to the insertion of the patellar tendon. The ATT-metaphysis angle (ATT-M) was defined by the angle between the tangents of the anterior metaphyseal cortical and the anterior cortical of the ATT. The height of the patella was also measured as described by Caton and Deschamps. The form of the patella on the lateral was described according to the Grelsamer criteria, and its form on the 30° axial view according to the Wiberg classification. The presence of trochelar dyplasia was determined using the Dejour method. The statistical analysis accepted p < 0.05 as significant. The coefficients of correlation R were calculated with a ½ log covariance matrix [1+R]/[1−R]. Results: The form of the ATT was given by the minimal value between the ATT-D and the ATT-M. This angle measurement revealed major variation. Three types of ATT were defined: type I 0≤ATT-M≤15 and ATT-D≤5, type II 15 < ATT-M < 20 and 5 < ATT-D < 10 and type III 20≤ATT-M 10≤ATT-D. There was an obvious correlation with the form of the patellar apex. The type III form of the patella was always associated with a type I ATT; there was a significantly association between patella type I and ATT type II and patella type III and ATT type I. There was no correlation with the height of the patella or with the form of the trochlea or the patella. Conclusion: The form of the ATT is quantifiable and becomes a parameter to consider in the analysis of patellofemoral osteoarthritis

Aims

The Oxford Shoulder Score (OSS) is a 12-item measure commonly used for the assessment of shoulder surgeries. This study explores whether computerized adaptive testing (CAT) provides a shortened, individually tailored questionnaire while maintaining test accuracy.

Aims

It is well described that patients with bone and joint infections (BJIs) commonly experience significant functional impairment and disability. Published literature is lacking on the impact of BJIs on mental health. Therefore, the aim of this study was to assess health-related quality of life (HRQoL) and the impact on mental health in patients with BJIs.

This study in UCA (ultra clean air) during TKR (total knee replacement) quantified wound bacterial counts, assessed the relationship to air counts and compared BES (body exhaust suits) with Rotecno occlusive clothing. Fifty TKR were randomly allocated to scrub teams wearing BES or Rotecno occlusive clothing. Air bacterial counting within 30cm of a wound is the established methodology to define air cleanliness. Reliable wound bacterial counting should be a more precise index of infection risk however, to date, there is no established accurate method. The TSMI (tetrazolium stained membrane imprint) method of bacterial wound counting has been validated in a tissue model and human surgical wounds in conventionally ventilated theatres. This method remains to be assessed in UCA where wounds may be too clean for bacteria to be detected accurately. We used air counts within 30cm of the wound and tested the TSMI method in wounds. Bacteria were recovered from 62% of the wounds. The mean air count wearing BES was 0. 5 cfu/m3 compared with 1. 0 cfu/m3 with Rotecno. The air counts were significantly higher with Rotecno clothing (p=0. 014, Toeplitz covariance analysis). The mean wound count was 14 bacteria/ wound with BES and 8 bacteria/wound with Rotecno. Although the counts were higher with BES the difference was not significant (p=0. 7, MannWhitney U test). There was no significant correlation between air and wound counts (r = 0. 108, Spearman’s). On first impression Rotecno occlusive clothing would appear to be less effective than BES on account of the higher air counts. However wounds were equally contaminated with both clothing types. As there is no relationship between wound and air counts, this suggests that at very low levels of air contamination the contribution of bacteria to the wound from the air is irrelevant. Even doubling of air counts from 0. 5 to 1. 0 cfu/m3 had no detectable effect on the wound

Aims

Spinopelvic characteristics influence the hip’s biomechanical behaviour. However, to date there is little knowledge defining what ‘normal’ spinopelvic characteristics are. This study aims to determine how static spinopelvic characteristics change with age and ethnicity among asymptomatic, healthy individuals.

Aims

It is not clear which type of casting provides the best initial treatment in adults with a distal radial fracture. Given that between 32% and 64% of adequately reduced fractures redisplace during immobilization in a cast, preventing redisplacement and a disabling malunion or secondary surgery is an aim of treatment. In this study, we investigated whether circumferential casting leads to fewer fracture redisplacements and better one-year outcomes compared to plaster splinting.

Aims

Repeated lumbar spine surgery has been associated with inferior clinical outcomes. This study aimed to examine and quantify the impact of this association in a national clinical register cohort.

Aims

Olecranon fractures are usually caused by falling directly on to the olecranon or following a fall on to an outstretched arm. Displaced fractures of the olecranon with a stable ulnohumeral joint are commonly managed by open reduction and internal fixation. The current predominant method of management of simple displaced fractures with ulnohumeral stability (Mayo grade IIA) in the UK and internationally is a low-cost technique using tension band wiring. Suture or suture anchor techniques have been described with the aim of reducing the hardware related complications and reoperation. An all-suture technique has been developed to fix the fracture using strong synthetic sutures alone. The aim of this trial is to investigate the clinical and cost-effectiveness of tension suture repair versus traditional tension band wiring for the surgical fixation of Mayo grade IIA fractures of the olecranon.

In general TKA can be divided into two distinct groups: cruciate retaining and cruciate substituting. The cam and post of the latter system is in fact a mechanical substitution of the intricate posterior cruciate ligament. In our previous work we and many other investigators have focused on the movement of the femoral component relative to the tibial tray. Little information is available about the relative movement between the cam part of the femoral component and the post of the tibial insert. In this study we determine the distance and the changes in distance between the cam of the femoral component and the tibial post during extension, flexion at 90° and full flexion. The secondary purpose is to analyse possible differences between FBPS and MBPS TKA. Methods. 12 subjects' knees were imaged using fluoroscopy from extension over 90° to maximum kneeling flexion. The images were digitized. The 3-dimensional (3D) position and orientation of the implant components were determined using model-based shape-matching techniques, manual matching, and image-space optimization routines. The implant surface model was projected onto the geometry-corrected image, and its 3D pose was iteratively adjusted to match its silhouette with the silhouette of the subject's TKA components. The results of this shapematching process have standard errors of approximately 0.5° to 1.0° for rotations and 0.5 mm to 1.0 mm for translations in the sagittal plane. Joint kinematics were determined from the 3D pose of each TKA component using the 3-1-2 Cardan angle convention. This process resulted in a distance map of the femoral and tibial surfaces, from which the minimum separations were determined for the purpose of this study between cam and post (fig1.). Separation distances between the tibial polyethylene (PE) insert's post and the femoral prosthesis component have been calculated in three steps. First, the surface models of all three components as well as their position and orientation were extracted from the data files produced by the fluoroscopic kinematic analysis. Next, a set of 12 points were located on the post of each tibial insert (fig2.). Finally, for each point, the distance to the femoral component was quantified. For each step in this process, custom MATLAB. (r). (The MathWorks(tm) Inc., Natick, MA, USA) programs were used. For each of the 12 points on the post, a line was constructed through the point and parallel to the outward-facing local surface normal of the post. The resulting set of lines was then intersected with the femoral component model. Intersection points where lines ran “out of” the femoral component, detected by a positive dot product of the femoral component surface normal with the post surface normal (used to define the line), were discarded. Finally, the distances between the 12 points on the post and the intersection points on each line were calculated. For each line, the smallest distance was retained as a measure of the separation between insert and femoral component. Where a line did not intersect the femoral component, the corresponding separation distance was set to infinity. In each position, distances are measured at 6 pairs of points. Two indices of asymmetry are analysed: . The absolute difference between both measurements within a pair. Perfect symmetry is present when this absolute difference equals zero. The proportion of pairs where one of both measurements equals infinity. Indeed, this situation refers to the presence of ‘extreme’ asymmetry. A linear model for repeated measures is used to analyse the absolute differences as a function of the between-subjects factor condition (mobile bearing or fixed bearing) and the within-subject factors position (4 levels) and pair (6 levels). More specifically, a direct likelihood approach is adopted using a compound symmetric covariance matrix. Results. There is a significant difference in absolute difference between the fixed and mobile bearing condition (p=0.046). On average, the absolute difference is higher in the fixed bearing condition, 1.75 (95%CI: 1.39;2.11) vs 1.20 (95%CI:0.78;1.62). (fig2.). Conclusion. The separation distances between post and cam show less asymmetry in the Rotating platform TKA, meaning less or no contact between the post and cam surfaces which are possible sources of wear

Aims

Nearly 99,000 total knee arthroplasties (TKAs) are performed in UK annually. Despite plenty of research, the satisfaction rate of this surgery is around 80%. One of the important intraoperative factors affecting the outcome is alignment. The relationship between joint obliquity and functional outcomes is not well understood. Therefore, a study is required to investigate and compare the effects of two types of alignment (mechanical and kinematic) on functional outcomes and range of motion.

Aims

A pilon fracture is a severe ankle joint injury caused by high-energy trauma, typically affecting men of working age. Although relatively uncommon (5% to 7% of all tibial fractures), this injury causes among the worst functional and health outcomes of any skeletal injury, with a high risk of serious complications and long-term disability, and with devastating consequences on patients’ quality of life and financial prospects. Robust evidence to guide treatment is currently lacking. This study aims to evaluate the clinical and cost-effectiveness of two surgical interventions that are most commonly used to treat pilon fractures.

Aims

Modular dual mobility (DM) prostheses in which a cobalt-chromium liner is inserted into a titanium acetabular shell (vs a monoblock acetabular component) have the advantage of allowing supplementary screw fixation, but the potential for corrosion between the liner and acetabulum has raised concerns. While DM prostheses have shown improved stability in patients deemed ‘high-risk’ for dislocation undergoing total hip arthroplasty (THA), their performance in young, active patients has not been reported. This study’s purpose was to assess clinical outcomes, metal ion levels, and periprosthetic femoral bone mineral density (BMD) in young, active patients receiving a modular DM acetabulum and recently introduced titanium, proximally coated, tapered femoral stem design.

Objectives

This investigation sought to advance the work published in our prior biomechanical study (Journal of Orthopaedic Research, 2016). We specifically sought to determine whether there are additional easy-to-measure parameters on plain radiographs of the proximal humerus that correlate more strongly with ultimate fracture load, and whether a parameter resembling the Dorr strength/quality characterisation of proximal femurs can be applied to humeri.

Objectives

In order to address acetabular defects, porous metal revision acetabular components and augments have been developed, which require fixation to each other. The fixation technique that results in the smallest relative movement between the components, as well as its influence on the primary stability with the host bone, have not previously been determined.