60 patient where included in this comparative study. Patients where divided into 3 groups. Group A including TKR done navigation guided in a navigation techniques experienced center. Group B including patient done navigation guided in less experienced center. Group c including patients done conventionally by an experienced surgeon. Accuracy was the primary end point. Where an independent observer was requested to comment on the post operative x-ray blindly and to measure accuracy using software. Result showed no significant difference in post operative radiological accuracy in the 3 groups.
Aims. The optimum type of antibiotics and their administration route for treating Gram-negative (GN) periprosthetic joint infection (PJI) remain controversial. This study aimed to determine the GN bacterial species and antibacterial resistance rates related to clinical GN-PJI, and to determine the efficacy and safety of intra-articular (IA) antibiotic injection after one-stage revision in a GN pathogen-induced PJI rat model of total knee arthroplasty. Methods. A total of 36 consecutive PJI patients who had been infected with GN bacteria between February 2015 and December 2021 were retrospectively recruited in order to analyze the GN bacterial species involvement and antibacterial resistance rates. Antibiotic susceptibility assays of the GN bacterial species were performed to screen for the most sensitive antibiotic, which was then used to treat the most common GN pathogen-induced PJI rat model. The rats were randomized either to a PJI control group or to three meropenem groups (intraperitoneal (IP), IA, and IP + IA groups). After two weeks of treatment, infection control level, the side effects, and the volume of antibiotic use were evaluated. Results. Escherichia coli was the most common pathogen in GN-PJI, and meropenem was the most sensitive antibiotic. Serum inflammatory markers, weightbearing activity, and Rissing score were significantly improved by meropenem, especially in the IA and IP + IA groups ( p < 0.05). Meropenem in the IA group eradicated E. coli from soft-tissue, bone, and prosthetic surfaces, with the same effect as in the IP + IA group.
The primary aim of this study was to report the radiological outcomes of patients with a dorsally displaced distal radius fracture who were randomized to a moulded cast or surgical fixation with wires following manipulation and closed reduction of their fracture. The secondary aim was to correlate radiological outcomes with patient-reported outcome measures (PROMs) in the year following injury. Participants were recruited as part of DRAFFT2, a UK multicentre clinical trial. Participants were aged 16 years or over with a dorsally displaced distal radius fracture, and were eligible for the trial if they needed a manipulation of their fracture, as recommended by their treating surgeon. Participants were randomly allocated on a 1:1 ratio to moulded cast or Kirschner wires after manipulation of the fracture in the operating theatre. Standard posteroanterior and lateral radiographs were performed in the radiology department of participating centres at the time of the patient’s initial assessment in the emergency department and six weeks postoperatively. Intraoperative fluoroscopic images taken at the time of fracture reduction were also assessed.Aims
Methods
A variety of surgical methods and strategies have been demonstrated for Andersson lesion (AL) therapy. In 2011, we proposed and identified the feasibility of stabilizing the spine without curettaging the vertebral or discovertebral lesion to cure non-kyphotic AL. Additionally, due to the excellent reunion ability of ankylosing spondylitis, we further came up with minimally invasive spinal surgery (MIS) to avoid the need for both bone graft and lesion curettage in AL surgery. However, there is a paucity of research into the comparison between open spinal fusion (OSF) and early MIS in the treatment of AL. The purpose of this study was to investigate and compare the clinical outcomes and radiological evaluation of our early MIS approach and OSF for AL. A total of 39 patients diagnosed with AL who underwent surgery from January 2004 to December 2022 were retrospectively screened for eligibility. Patients with AL were divided into an MIS group and an OSF group. The primary outcomes were union of the lesion on radiograph and CT, as well as the visual analogue scale (VAS) and Oswestry Disability Index (ODI) scores immediately after surgery, and at the follow-up (mean 29 months (standard error (SE) 9)). The secondary outcomes were total blood loss during surgery, operating time, and improvement in the radiological parameters: global and local kyphosis, sagittal vertical axis, sagittal alignment, and chin-brow vertical angle immediately after surgery and at the follow-up.Aims
Methods
Eccentric reductions may become concentric through femoral head ‘docking’ (FHD) following closed reduction (CR) for developmental dysplasia of the hip (DDH). However, changes regarding position and morphology through FHD are not well understood. We aimed to assess these changes using serial MRI. We reviewed 103 patients with DDH successfully treated by CR and spica casting in a single institution between January 2016 and December 2020. MRI was routinely performed immediately after CR and at the end of each cast. Using MRI, we described the labrum-acetabular cartilage complex (LACC) morphology, and measured the femoral head to triradiate cartilage distance (FTD) on the midcoronal section. A total of 13 hips with initial complete reduction (i.e. FTD < 1 mm) and ten hips with incomplete MRI follow-up were excluded. A total of 86 patients (92 hips) with a FTD > 1 mm were included in the analysis.Aims
Methods
The use of high tibial osteotomy (HTO) to delay total knee arthroplasty (TKA) in young patients with osteoarthritis (OA) and constitutional deformity remains debated. The aim of this study was to compare the long-term outcomes of TKA after HTO compared to TKA without HTO, using the time from the index OA surgery as reference (HTO for the study group, TKA for the control group). This was a case-control study of consecutive patients receiving a posterior-stabilized TKA for OA between 1996 and 2010 with previous HTO. A total of 73 TKAs after HTO with minimum ten years’ follow-up were included. Cases were matched with a TKA without previous HTO for age at the time of the HTO. All revisions were recorded. Kaplan-Meier survivorship analysis was performed using revision of metal component as the endpoint. The Knee Society Score, range of motion, and patient satisfaction were assessed.Aims
Methods
Several artificial bone grafts have been developed but fail to achieve anticipated osteogenesis due to their insufficient neovascularization capacity and periosteum support. This study aimed to develop a vascularized bone-periosteum construct (VBPC) to provide better angiogenesis and osteogenesis for bone regeneration. A total of 24 male New Zealand white rabbits were divided into four groups according to the experimental materials. Allogenic adipose-derived mesenchymal stem cells (AMSCs) were cultured and seeded evenly in the collagen/chitosan sheet to form cell sheet as periosteum. Simultaneously, allogenic AMSCs were seeded onto alginate beads and were cultured to differentiate to endothelial-like cells to form vascularized bone construct (VBC). The cell sheet was wrapped onto VBC to create a vascularized bone-periosteum construct (VBPC). Four different experimental materials – acellular construct, VBC, non-vascularized bone-periosteum construct, and VBPC – were then implanted in bilateral L4-L5 intertransverse space. At 12 weeks post-surgery, the bone-forming capacities were determined by CT, biomechanical testing, histology, and immunohistochemistry staining analyses.Aims
Methods
Arthrodesis of the first metatarsophalangeal joint (MTPJ) has been reported as gold standard for the treatment of advanced hallux rigidus and is a well-documented procedure. However, many patients demand a mobile MTPJ and therefore joint sparing procedures like MTPJ-arthroplasty have gained popularity. The aim of the present study was to present first mid-term results after hemiarthroplasty to treat advanced osteoarthritis of the first MTPJ. Between April 2006 and October 2013, a total of 81 hemiprostheses (AnaToemic®, Arthrex) in 71 consecutive patients (44 females, 27 male, 10 bilateral; mean age, 58 [range, 45–82]) were implanted at the St. Vincent Hospital Vienna (Austria). The indication for surgery was persistent MTPJ pain after failed conservative treatment combined with radiologic evidence of osteoarthritis (advanced hallux rigidus grade II-IV). Patients were clinically examined using the American Orthopaedic Foot and Ankle Society (AOFAS) score before surgery and at the final follow-up visit. Patient's satisfaction with the treatment was recorded.
Introduction. The purpose of this study was to evaluate the mid-term clinical and radiological results in patients who were managed by double metal augmentations in proximal tibial uncontained bony defects undergoing primary or revision total knee arthroplasty. Materials and Methods. We performed double metal augmentations in proximal tibial uncontained bony defects undergoing total knee arthroplasty. Out of total 14 patients, 8 patients (4 priamry arthroplasty, 4 revision arthroplasty), mean 61.3 (50–80) years, were available for review at least 5 years follow up. The average follow up period was 86.3(60–99) months. Range of motion, American Knee Society Score were evaluated pre- and postoperatively as a clinical values. Another clinical assessments undertaken at the final reviews, Western Ontario and McMaster Universities osteoarthritis index (WOMAC), Oxford knee score (OKS), Short Form-36 (SF-36), Lower extremity functional scale (LEFS), and Lower extremity activity scale (LEAS) were checked.
Starting in 1977 a new cemented stem made of titanium alloy (with vanadium) was designed regarding some principle: rectangular shape, smooth surface covered with thin layer of titanium oxide, filling the medullar cavity. As a consequence: a thin layer of cement. It was designed with a collar. Initial Cementing technique used dough cement, vent tube and finger packing; then we applied cement retractor low viscosity cement and sometimes Harris Syringe. At the moment we went back to initial technique plus a cement retractor made of polyethylene. Many papers looked at long term follow up results depicting about 98 to 100 percent survivors at 10 years and 95 to 98% at 20 years (Hernigou, Hamadouche, Nizard, El Kaim). Clinical as well as radiological results are available.
One of the most important factors on which Total Knee Replacements results depend is accuracy of restoration of normal mechanical axis. It is believed that computer navigated TKR give better implants position therefore should improve long term results. We decided to check if computer navigation actually improves restoration of mechanical axis and implants placement in a single surgeon, single implant type series. We prospectively assessed 58 patients (60 knees). Each group (navigated versus non navigated) consisted of 30 knees. Patients were assessed clinically and radiographically using weight bearing full-length AP and short lateral films (PACS and IMPAX software). Clinical Results at 2 years were comparable in both groups (89% vs. 88% good or excellent result).
Treatment of the femoral head necrosis with severe extensive collapse in young adults and adolescents are still challenging. We thought preserve the joint and bone stock were important factor for the treatment of femoral head necrosis in young patients. We reviewed the posterior rotational osteotomy for younger patients with severe osteonecrosis. The advantages of posterior rotational osteotomy are; the necrotic area is moved to non-weight bearing portion. The posterior column artery is shifted medially without vascular damage by rotation. Postoperative uncollapsed anterior viable areas are moved to the loaded portion below the acetabular roof in flexed positions. Eighty five hips of 66 young adults (less than 50 years old, mean age; 31 years) with extensive necrosis treated by posterior rotational osteotomy were reviewed with more than 5 year follow up with a mean of 9 years. Results of 13 hips of 12 adolescents (mean age; 14 years) with extensive collapsed necrosis treated by this procedure were also studied with a mean of 6.5 years. A mean degree of posterior rotation was 121. Recollapse was prevented in 77 hips (91%) of adults, and all 13 hips of adolescents on final AP radiographs. Collapsed lesion was remodeled well and resphericity of the postoperative transferred medial collapsed femoral head on final AP radiographs was observed. However, some of the cases were out of indication of the joint preserving procedure showing extensive lesion. In these cases, we performed the MAYO conservative stem for preserving bone stock.
Distraction osteogenesis (DO) is a useful orthopaedic procedure employed to lengthen and reshape bones by stimulating bone formation through controlled slow stretching force. Despite its promising applications, difficulties are still encountered. Our previous study demonstrated that pulsed electromagnetic field (PEMF) treatment significantly enhances bone mineralization and neovascularization, suggesting its potential application. The current study compared a new, high slew rate (HSR) PEMF signal, with different treatment durations, with the standard Food and Drug Administration (FDA)-approved signal, to determine if HSR PEMF is a better alternative for bone formation augmentation. The effects of a HSR PEMF signal with three daily treatment durations (0.5, one, and three hours/day) were investigated in an established rat DO model with comparison of an FDA-approved classic signal (three hrs/day). PEMF treatments were applied to the rats daily for 35 days, starting from the distraction phase until termination. Radiography, micro-CT (μCT), biomechanical tests, and histological examinations were employed to evaluate the quality of bone formation.Aims
Methods
Periacetabular osteotomy (PAO) is an established treatment for acetabular dysplasia. It has also been proposed as a treatment for patients with acetabular retroversion. By reviewing a large cohort, we aimed to test whether outcome is equivalent for both types of morphology and identify factors that influenced outcome. A single-centre, retrospective cohort study was performed on patients with acetabular retroversion treated with PAO (n = 62 hips). Acetabular retroversion was diagnosed clinically and radiologically (presence of a crossover sign, posterior wall sign, lateral centre-edge angle (LCEA) between 20° and 35°). Outcomes were compared with a control group of patients undergoing PAO for dysplasia (LCEA < 20°; n = 86 hips). Femoral version was recorded. Patient-reported outcome measures (PROMs), complications, and reoperation rates were measured.Aims
Methods
The purpose of this study was to compare the clinical and radiological results of the PFC flex mobile bearing design with those of the LPS flex fixed bearing design in high-flex total knee arthroplasty. Between January 2005 and November 2006, forty-six patients who received PFC flex mobile bearing prosthesis in one knee and LPS flex fixed bearing prosthesis in the contralateral knee followed up for a minimum 2 years were evaluated. Clinical results were assessed using the ROM, HSS score, the Knee rating systems of the knee society, WOMAC score and SF-36.
This prospective study was undertaken to compare the clinical and radiological results achieved using navigation assisted minimally invasive (NA-MIS) and conventional (CON) techniques in bilateral total knee arthroplasty (TKA). Forty-two bilateral patients with a minimum 2-year follow-up who were available for study after NA-MIS TKA were included in this study. Clinical evaluations (ROM, HSS and WOMAC scores) were performed at 3 and 6 months and at 1 &
2 year postoperatively. Patient subjective preferences and radiological accuracies were compared at 1 year postoperatively. Preoperative HSS scores were 68.5 in the NA-MIS group and 66.5 in the CON group, and these scores improved to 93.6 and 92.5 at 1 year postoperatively, respectively. Knees had a higher average HSS score in NA-MIS group than in the CON group till six months, but not after nine months postoperatively. In terms of WOMAC scores, pain scores in the NA-MIS group were better up to nine months postoperatively, but not at one &
2 year postoperatively, and total WOMAC scores were better up to six months, but not after nine months postoperatively. ROM was comparable in both groups at all times. However, more patients preferred NA-MIS sides than CON sides.
Aims: 1. Analysis of indications for THA in young adults with osteoarthrosis, 2. Evaluation of clinical and radiological end results, 3. Investigation of complications after metal-to-metal THA. Material: 75 THAs with metal-tometal cementless endoprosthesis in 75 patients which had been operated between 1997–2002 were retrospectively evaluated. There 50 women and 25 men (mean age: 39 years old). The mean time of follow-up was 2,8 years (form 6 to 48 months). Etiologic factors of osteo-arthrosis in operated hips were: idiopathic arthrosis in 50 hips, CHD in 18 hips, post-traumatic lesions in 3 hips, aseptic necrosis of the femoral capitis. Metal-to-metal THA with the cementless endoprosthesis was made in all evaluated cases with: Alloclassic systeml Ð 66, other systems Ð 9.Methods: The clinical evaluation was performed with Merle dñAbugine score. The radiological evaluation of THA was based on criterion proposed by joined committee of The Hip Society, SICOT and AAOS. Results: The mean postoperative clinical result in the study group is 5,5 p. in Merle dñAbugine score.
Moderate to severe acetabular bone loss in revision hip arthroplasty is challenging. Various treatment options are available but the medium to long term results have not been encouraging. The porus tantalum uncemented cup may be used successfully to address moderate to severe bone loss in acetabulum revision surgery. We report a single surgeon series. Between December 2003 and June 2007, 39 patients (43 hips) underwent hip revision surgery. There were 17 men and 23 women with a mean age at surgery of 71.9 years (range 36–96). The mean follow up was 40 months (range 24–66). A porus tantulum modular multi hole uncemented cup was used in all cases. At time of assessment 6 patients had died, 2 patients developed dementia and another 2 patients were not contactable. All 10 patients had no significant clinical or radiological concerns at their last orthopaedic review. The remaining 29 alive patients (33 hips) were available for clinical evaluation. Harris hip score of these 33 hips showed, 24 excellent or good, 7 fair and 2 poor.
Purpose: Metal-on-metal articulations in total hip arthroplasty (THA) have been recently re-introduced for the treatment of osteoarthritis. There have been excellent short-term clinical outcomes reported. The long-term clinical results of these implants are still unknown. In this study, we examined the four to ten -year results of metal-on-metal total hip arthroplasty at our institution. Method: All patients receiving a metal-on-metal prosthesis were prospectively registered in a computerized database. The period July 1997 – May 2003 was selected for analysis. This group contained 251 cases (207 patients) and had an average follow-up of 6.8 years. Of the 251 implants the femoral head components were either Metasul. ™. (203) or Ultamet. ™. (48) and the acetubular component Fitek. ™. (12), Interop. ™. (191) or Pinnacle. ™. (48). All patients were assessed with the Harris hip and UCLA activity scores at routinely scheduled follow-up visits. The mean age of patients at surgery was 52 years (18 to 70 years old). The average follow-up was of 6.8 years (4.2–10 years). No patients were lost to follow-up. Results: The mean UCLA and Harris hip score pre-operatively were 3.6 (1–8) and 42 (15–81), respectively. Values of the UCLA and the Harris hip scores on the most recent follow-up visit were 7.0 (60% of patients had a score equal to or greater than 7) and 85 (70% of patients had a score equal to or greater than 85), respectively. Thirteen hips (5.1%) were revised in total: 1 (0.4%) for early deep infection, 1 (0.4%) for revision of undersized stem and 11 (4.3%) for acetabular revisions due to manufacturing defects.
Introduction. Chronic radial head dislocation in children after trauma is a serious condition. Often the dislocation is overseen initially and is a part of the Monteggia fracture complex with anterior bowing of the ulna. Typical complaints are pain, decreased ROM and cubitus valgus. Radial head dysplasia often occurs. The treatment of this condition is debated. Only few series of patients treated with open reduction and ulnar osteotomy exists with long-term follow up. We present a group of rare patients with long-time follow-up treated by only two surgeons through a period of 16 years. Materials and Methods. All 16 patients had anterior radial head dislocation (Bado type 1). Mean age at the time of traumatic dislocation was 6 years ranging from 2 to 9. We found a mean delay of 17 (range 1–83) months before open reduction and ulnar open wedge osteotomy. In 8 cases reconstruction of the annular ligament was performed and in 6 patients temporary transarticular fixation of the radial head with a k-wire was performed. Follow-up time was 8 (range 3–17) years postoperatively. Patients were investigated with bilateral x-ray, arthrosis status, congruency of the radiocapitellar joint, Oxford Elbow Score, force measurements and range of motion. Results. There were no major complications to surgery such as infection, nerve palsies or pseudarthrosis.