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Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_13 | Pages 38 - 38
1 Dec 2022
Kim J Alraiyes T Sheth U Nam D
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Thoracic hyperkyphosis (TH – Cobb angle >40°) is correlated with rotator cuff arthropathy and associated with anterior tilting and protraction of scapula, impacting the glenoid orientation and the surrounding musculature. Reverse total shoulder arthroplasty (RTSA) is a reliable surgical treatment for patients with rotator cuff arthropathy and recent literature suggests that patients with TH may have comparable range of motion after RTSA. However, there exists no study reporting the possible link between patient-reported outcomes, humeral retroversion and TH after RTSA. While the risk of post-operative complications such as instability, hardware loosening, scapular notching, and prosthetic infection are low, we hypothesize that it is critical to optimize the biomechanical parameters through proper implant positioning and understanding patient-specific scapular and thoracic anatomy to improve surgical outcomes in this subset of patients with TH.

Patients treated with primary RTSA at an academic hospital in 2018 were reviewed for a two-year follow-up. Exclusion criteria were as follows: no pre-existing chest radiographs for Cobb angle measurement, change in post-operative functional status as a result of trauma or medical comorbidities, and missing component placement and parameter information in the operative note. As most patients did not have a pre-operative chest radiograph, only seven patients with a Cobb angle equal to or greater than 40° were eligible. Chart reviews were completed to determine indications for RTSA, hardware positioning parameters such as inferior tilting, humeral stem retroversion, glenosphere size/location, and baseplate size. Clinical data following surgery included review of radiographs and complications. Follow-up in all patients were to a period of two years. The American Shoulder and Elbow Surgeons (ASES) Shoulder Score was used for patient-reported functional and pain outcomes.

The average age of the patients at the time of RTSA was 71 years old, with six female patients and one male patient. The indication for RTSA was primarily rotator cuff arthropathy. Possible correlation between Cobb angle and humeral retroversion was noted, whereby, Cobb angle greater than 40° matched with humeral retroversion greater than 30°, and resulted in significantly higher ASES scores. Two patients with mean Cobb angle of 50° and mean humeral retroversion 37.5° had mean ASES scores of 92.5. Five patients who received mean humeral retroversion of 30° had mean lower ASES scores of 63.7 (p < 0 .05). There was no significant correlation with glenosphere size or position, baseplate size, degree of inferior tilting or lateralization.

Patient-reported outcomes have not been reported in RTSA patients with TH. In this case series, we observed that humeral stem retroversion greater than 30° may be correlated with less post-operative pain and greater patient satisfaction in patients with TH. Further clinical studies are needed to understanding the biomechanical relationship between RTSA, humeral retroversion and TH to optimize patient outcomes.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_IV | Pages 568 - 568
1 Oct 2010
Tuschel A Meissl M Ogon M Schenk S
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Introduction: Obesity is often considered as a risk-factor for higher complication rates and worse clinical outcome of fusion surgery in the lumbar spine and is therefore sometimes not performed in obese patients despite relative indication for surgery. The goal of this study was to evaluate whether BMI is a predictive factor for clinical outcome after monosegmental fusion surgery in the lumbar spine.

Patients and Methods: The present study is a retrospective analysis of prospectively collected data in a consecutive series of patients.

Between April 2002 and April 2007, a total of 467 patients underwent monosegmental lumbar fusion in a single spine-center. Preoperatively and at 6 weeks and 1 year follow-up, SF36 and Oswestry-Disability-Index scores were collected. We excluded patients who underwent surgery due to infections, tumor and trauma, as well as revision surgeries, and all patients with incomplete datasets, so that 223 patients were included in the study. Of those patients, variables considered as risk-factors like age, BMI and the presence of diabetes mellitus were assessed from the medical records. A multiple regression model for those parameters and clinical outcome was cretated. Results: In an unadjusted model, BMI did not at all predict clinical outcome, in a multivariate model adjusted for baseline outcome values of SF36, Oswestry-Disability index and age, a slight trend towards negative correlation between BMI and outcome could be shown (p=0.06).

Conclusion: This study suggests that BMI alone is not a good predictor of clinical outcome of monosegmental lumbar fusion and that therefore this kind of surgery should not be withheld from patients only because of obesity.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_II | Pages 246 - 246
1 Jul 2008
GLARD Y LAUNAY F VIEHWEGER E JOUVE J BOLLINI G
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Purpose of the study: In spina bifida, independently of limb paralysis, spinal deformation can cause significant static disorders (scoliosis, kyphosis, or hyperlordosis) which in turn cause significant disability. These deformations generally develop during growth. We wanted to determine the predictive value of a clinical classification based on the neurological examination at five years for risk of spinal deformation.

Material: This retrospective study included 163 patients. Groups were defined on the basis of motor function determined by the neurological examination at five years: group I: L5 or below (all patients in this group had motor deficit leaving at least one L5 segment intact); group II: L3–L4; group III: L1–L2; group IV: T12 and above.

Results: Results showed that group I was a factor predictive of an absence of future spinal deformation. Groups III and IV were predictive of presence of a future spinal deformation. Group IV was predictive of future kyphosis.

Discussion: It is well known that the higher the neurological lesion in spina bifida, the higher the rate of spinal deformation. No work has however set the limits nor provided predictive rules useful in clinical practice. Our work demonstrated that this classification based on the motor function established by neurological examination at five years can predict which children have a risk of developing a spinal deformation and thus enabling early detection and treatment.

Conclusion: This neurological classification can be used as a clinical tool for the prognostic evaluation of spina bifida.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 82 - 82
1 Mar 2006
Adams CF Schulte-Bockholt M Heppert D Wentzensen V
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Problem: Deep infection after hip- or knee-replacement is a severe complication that may lead to implant removal or arthrodesis.

Aim: In our hospital intraoperativ subcoutanues culture samples were taken before wound closure. We wanted to know if positive cultures are of any predicitive value in relation to early or late periprosthetic infection. If so, is there a consequence in treatment ? Also costs were analysed.

Material and methods: In 2002 we performed 167 primary hip and knee replacements. We retrospectivaly analysed the outcome of 159 cases over a follow-up period of up to 28 month.

Results: In 96.8% of the cases a culture sample was taken. Of these 5.8% showed germ growth. In only 4 cases positive cultures were followed by a change in treatment, either antibiotics or revision. Of nine patients with revision surgery only one had a positive culture. Four cases showed germ growth during revision surgery after sterile cultures during implantation. Most often different bacterias were found in primary and revision surgery. In 1.25% deep periprosthetic infection occured. One required second stage knee-replacement, one case ended in resection arthroplasty.

Conclusion: Intraoperative culture sample is of no predictive value in primary joint replacement. There is no correlation between positiv cultures and indication for revision surgery. However costs for culture analysis and antibiotics are low compared to the increase of expense caused by periprosthetic infections.


Introduction

Success rate after Debridement-Irrigation, Antibiotic Therapy and Implant Retention (DAIR) for treatment of Acute Haematogenous (AH) and Early Post-surgical (EP) periprosthetic joint infection (PJI) varies widely among published studies. Prosthesis exchange is recommended to treat PJI after a failed DAIR. However, no early postoperative prognostic factors permitting to identify future failures have been described.

Aim

Identify early prognostic factor of failure after DAIR in order to propose efficient treatment before onset of chronic PJI.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_1 | Pages 201 - 201
1 Jan 2013
Macnair R Pearce C Sexton S
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Introduction. Urinary catheterisation can cause bacteraemia and therefore may be associated with a risk of infection in hip and knee arthroplasty. However postoperative urinary retention can be distressing for the patient. This study investigates the factors that might predict the need for postoperative catheterisation in order to help develop a protocol to decide who should be electively catheterised. Methods. A prospective blinded study of 128 consecutive patients undergoing lower limb arthroplasty was carried out. No patient underwent perioperative catheterisation. Data obtained included sex, age, joint (hip or knee replacement), prostate score (IPSS), previous urinary retention, comorbidities and residual bladder volume after attempted complete voiding measured using an ultrasound bladder scanner. The type of anaesthesia and the requirement for urinary catheterisation postoperatively were recorded. Predictive risk factors were identified using binary logistic regression, and expressed as odds ratios (OR) and 95% confidence intervals (CI). Results. The mean age was 69.5 years (SD 8.9). There were 56 males and 72 females. 38 patients (30%) required postoperative catheterisation. Logistic regression identified the following predictive risk factors: bladder scan volume per ml increase (OR 1.006; CI 1.000–1.012); male sex (OR 5.51; CI 2.01–15.16); previous catheter (OR 4.26; CI 1.53–11.82); spinal/epidural/combined spinal epidural (CSE) anaesthesia (OR 6.78; CI 1.75–26.32); moderate IPSS score (OR 5.15; CI 1.73–15.37); severe IPSS score (OR 3.53; CI 0.605–20.54). The specificity of our model is 91%, the positive predictor value 71% and negative predictor value 82%. Discussion. Post-voiding bladder scan volume (1ml increase = 0.6% increased risk), male sex, history of retention, medium or high IPSS score and an epidural, spinal or CSE anaesthetic are independent risk factors that can be used preoperatively to predict the likelihood of postoperative retention


Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_10 | Pages 60 - 60
1 Oct 2022
Dudareva M Corrigan R Hotchen A Muir R Sattar A Scarborough C Kumin M Atkins B Scarborough M McNally M Collins G
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Aim. Recurrence of bone and joint infection, despite appropriate therapy, is well recognised and stimulates ongoing interest in identifying host factors that predict infection recurrence. Clinical prediction models exist for those treated with DAIR, but to date no models with a low risk of bias predict orthopaedic infection recurrence for people with surgically excised infection and removed metalwork. The aims of this study were to construct and internally validate a risk prediction model for infection recurrence at 12 months, and to identify factors that predict recurrence. Predictive factors must be easy to check in pre-operative assessment and relevant across patient groups. Methods. Four prospectively collected datasets including 1173 participants treated in European centres between 2003 and 2021, followed up to 12 months after surgery for orthopaedic infections, were included in logistic regression modelling [1–3]. The definition of infection recurrence was identical and ascertained separately from baseline factors in three contributing cohorts. Eight predictive factors were investigated following a priori sample size calculation: age, gender, BMI, ASA score, the number of prior operations, immunosuppressive medication, glycosylated haemoglobin (HbA1c), and smoking. Missing data, including systematically missing predictors, were imputed using Multiple Imputation by Chained Equations. Weekly alcohol intake was not included in modelling due to low inter-observer reliability (mean reported intake 12 units per week, 95% CI for mean inter-rater error −16.0 to +15.4 units per week). Results. Participants were 64% male, with a median age of 60 years (range 18–95). 86% of participants had lower limb orthopaedic infections. 732 participants were treated for osteomyelitis, including FRI, and 432 for PJI. 16% of participants experienced treatment failure by 12 months. The full prediction model had moderate apparent discrimination: AUROC (C statistic) 0.67, Brier score 0.13, and reasonable apparent calibration. Of the predictors of interest, associations with failure were seen with prior operations at the same anatomical site (odds ratio for failure 1.51 for each additional prior surgery; 95% CI 1.02 to 2.22, p=0.06), and the current use of immunosuppressive medications (odds ratio for failure 2.94; 95% CI 0.89 to 9.77, p=0.08). Conclusions. This association between number of prior surgeries and treatment failure supports the urgent need to streamline referral pathways for people with orthopaedic infection to specialist multidisciplinary units


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 585 - 585
1 Sep 2012
Albers C Steppacher S Ganz R Siebenrock K Tannast M
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The Bernese Periacetabular Osteotomy (PAO) has become the established method for treating developmental dysplasia of the hip. In the 1990s, the surgical technique was modified to avoid postoperative cam impingement due to uncorrected head neck offset or pincer impingement due to acetabular retroversion after reorientation. The goal of the study was to compare the survivorship of two series of PAOs with and without the modifications of the surgical technique and to calculate predictive factors for a poor outcome. A retrospective, comparative study of two consecutive series of PAOs with a minimum follow-up of 10 years was carried out. Series A included 75 PAOs performed between 1984 and 1987 and represent the first cases of PAO. Series B included 90 hips that underwent PAO between 1997 and 2000. In this series, emphasis was put on an optimal acetabular version next to the correction of the lateral coverage. Additionally, a concomitant arthrotomy was performed in every hip to check impingement-free range of motion after reorientation and in 50 hips (56%) an additional offset correction was performed. Survivorship analyses according to Kaplan and Meier were carried out and the endpoint was defined as conversion to a total hip arthroplasty, progression of osteoarthritis, or a Merle d'Aubign score 14. Predictive factors for poor outcome were calculated using the Cox-regression analysis. The cumulative 10-year survivorship of Series A was significantly decreased (77%; 95%-confidence interval [CI] 72–82%) compared to Series B (86%; 95%-CI 82–89%, p=0.005). Hips with an aspherical head showed a significantly increased survivorship if a concomitant offset correction was performed intraoperatively (90% [95%-CI 86–94%] versus 77% [95%-CI 71–82%], p=0.003). Preoperative factors predicting poor outcome included a high age at surgery, a Merle d'Aubign score 14, a positive impingement test, a positive Trendelenburg sign, limp, an increased grade of osteoarthritis according to Tönnis, and (sub-) luxation of the femoral head (Severin > 3). In addition, predictive factors related to the three dimensional orientation of the acetabular fragment were identified. These included total, anterior, and posterior acetabular over-coverage or under-coverage, acetabular retroversion or excessive anteversion, a lateral center edge angle < 22 °, an acetabular index > 14 °, and no offset correction in aspherical femoral heads. A good long term result after PAO mainly depends on optimal three-dimensional orientation of the acetabulum and impingement-free range of motion with correction of an aspherical head neck junction if necessary


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_IV | Pages 423 - 423
1 Apr 2004
Brander V Villoch C Robinson H Stulberg S Adams A
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Introduction: Hospital accrediting organizations have recently emphasized the evaluation of and response to postoperative pain as the “fifth vital sign”. However, there are no prospective studies describing normal pain patterns after TKA to guide appropriate clinical responses. Similarly, there are no studies describing those at risk for unusual pain. Purpose: To outline the pattern of normal recovery and identify factors predictive of significant pain after TKA. Method: Prospective, observational, single surgeon design. Inclusion criteria: primary, cemented TKA for osteoarthritis. Clinical & radiographic measures obtained pre-op and at 1,3,6 and 12 months post-operatively. Predictive factors and post-operative outcomes included body mass index visual analogue scale (VAS), demographics, physical therapy, and component design, alignment and fixation. Psychometric testing included the Beck Depression Inventory and McGill Pain Questionnaire. Results: 96 patients, 125 knees (mean age = 66, 55.2% women). Mean VAS at pre-op, 1,3, 6 and 12 month visits were 51.1(SD 23.8), 37.4(21.8), 27.0(22.2), 20.8(20.3), and 18.0(21.0), respectively. significant pain (VAS> 40) was reported by 61.51% of patients pre-op, 41.7% at 1 month, 24.0% 3 months, 16.7% 6 months, and 8.3% 12 months. There were no differences in pain based on the type of anesthesia, weight, age or gender. Preoperative elevated depression, anxiety and pain-related suffering descriptors predicted greater pain during the first 6 months after surgery, but did not ultimately affect recovery. Patients who had greater pain (VAS> 40) used more home and outpatient physical therapy (p=0.25). Conclusion: Contrary to common beliefs, many patients (22%) still experience significant pain up to six months after TKA, despite absence of clinical or radiographic abnormalities. significant pain (VAS > 40mm) after six months may be indicative of an abnormal pain experience. Preoperative pain, depression and suffering are associated with increased early pain andutilization of therapy


Bone & Joint Open
Vol. 3, Issue 5 | Pages 383 - 389
1 May 2022
Motesharei A Batailler C De Massari D Vincent G Chen AF Lustig S

Aims

No predictive model has been published to forecast operating time for total knee arthroplasty (TKA). The aims of this study were to design and validate a predictive model to estimate operating time for robotic-assisted TKA based on demographic data, and evaluate the added predictive power of CT scan-based predictors and their impact on the accuracy of the predictive model.

Methods

A retrospective study was conducted on 1,061 TKAs performed from January 2016 to December 2019 with an image-based robotic-assisted system. Demographic data included age, sex, height, and weight. The femoral and tibial mechanical axis and the osteophyte volume were calculated from CT scans. These inputs were used to develop a predictive model aimed to predict operating time based on demographic data only, and demographic and 3D patient anatomy data.


Aims

The aim of this study was to review the current evidence surrounding curve type and morphology on curve progression risk in adolescent idiopathic scoliosis (AIS).

Methods

A comprehensive search was conducted by two independent reviewers on PubMed, Embase, Medline, and Web of Science to obtain all published information on morphological predictors of AIS progression. Search items included ‘adolescent idiopathic scoliosis’, ‘progression’, and ‘imaging’. The inclusion and exclusion criteria were carefully defined. Risk of bias of studies was assessed with the Quality in Prognostic Studies tool, and level of evidence for each predictor was rated with the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) approach. In all, 6,286 publications were identified with 3,598 being subjected to secondary scrutiny. Ultimately, 26 publications (25 datasets) were included in this review.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_9 | Pages 28 - 28
1 Feb 2013
Macnair R Sexton S Pearce C
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Urinary catheterisation may be associated with a risk of infection in hip and knee arthroplasty, however post-operative urinary retention can be distressing for the patient. This study investigates the factors that might predict the need for post-operative catheterisation. A prospective blinded study of 128 consecutive patients undergoing lower limb arthroplasty was carried out. Data obtained included sex, age, joint (hip or knee), prostate score (IPSS), previous urinary retention, co-morbidities and residual bladder volume after attempted complete voiding measured using an ultrasound bladder scanner. Anaesthetic type and requirement for urinary catheterisation postoperatively were recorded. Predictive risk factors were identified using binary logistic regression, and expressed as odds ratios (OR) and 95% confidence intervals (CI). The mean age was 69.5 years. There were 56 males and 72 females. 38 patients (30%) required post-operative catheterisation. Logistic regression identified the following predictive risk factors: bladder scan volume per ml increase (OR 1.006; CI 1.000–1.012); male sex (OR 5.51; CI 2.01–15.16); previous catheter (OR 4.26; CI 1.53–11.82); spinal/epidural/combined spinal epidural anaesthesia (OR 6.78; CI 1.75–26.32); moderate IPSS score (OR 5.15; CI 1.73–15.37); severe IPSS score (OR 3.53; CI 0.605–20.54). Our model specificity is 91%, positive predictor value 71% and negative predictor value 82%


Bone & Joint 360
Vol. 8, Issue 3 | Pages 29 - 31
1 Jun 2019


Bone & Joint 360
Vol. 7, Issue 6 | Pages 29 - 31
1 Dec 2018