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Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_16 | Pages 19 - 19
1 Oct 2017
Masud S Guro R Mohan R Chandratreya A
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Oxford Medial Unicompartmental Knee Replacement (OMUKR) is a well-established treatment option for isolated medial compartment arthritis, with good patient reported outcome measures (PROMs). We present our results of the Oxford Domed Lateral Unicompartmental Knee Replacement (ODLUKR) to establish if patients benefit as much as with OMUKR. Retrospective review of prospectively collected data of a single surgeon series of consecutive UKR from 2007 to 2014 were collated with a minimum 2 years follow-up. PROMs data were collected using pre- and post-operative Oxford Knee Scores (OKS) (best score of 48). One hundred and twenty-eight OMUKR and 27 ODLUKR were performed in the study period. There was no significant difference in the age at time of surgery, but there were significantly more women in the ODLUKR group (74% vs 53%). There was no significant difference in pre-op OKS between the groups (OMUKR = 16/48; ODLUKR = 20/48), or the improvement in OKS post-op (OMUKR = 19 points; ODLUKR = 17 points). One ODLUKR was revised to Total Knee Replacement (TKR) for pain. There were three (11.1%) bearing dislocations, which were treated with thicker bearing exchange, with no subsequent problems. There were no bearing dislocations in the OMUKR. Four OMUKR were revised to TKR due to pain. The overall implant survivorship was 96.3% for ODLUKR and 96.9% for OMUKR. ODLUKR is a good treatment option for isolated lateral compartment arthritis and gives results equivalent to OMUKR. There is, however, an increased risk of bearing dislocation so should be performed by a high volume UKR surgeon


Orthopaedic Proceedings
Vol. 104-B, Issue SUPP_7 | Pages 30 - 30
1 Jul 2022
Middleton R Jackson W Alvand A Bottomley N Price A
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Abstract. Background. Since 2012 we have routinely used the cementless Oxford medial unicompartmental knee arthroplasty (mUKA), with microplasty instrumentation, in patients with anteromedial osteoarthritis (AMOA) meeting modern indications. We report the 10-year survival of 1000 mUKA with minimum 4-year follow-up. Methods. National Joint Registry (NJR) surgeon reports were interrogated for each senior author to identify the first 1,000 mUKAs performed for osteoarthritis. A minimum of 4 years follow-up was required. There was no loss to follow-up. The NJR status of each knee was established. For each mUKA revision the indication and mechanism of failure was determined using local patient records. The 10-year implant survival was calculated using life-table analysis. Results. The 1,000 mUKA cohort represented 55% of all primary knee replacements in the period, with an average age of 67.7 years and a 54%/46% male/female split. There were 17 revisions (11 for arthritis progression, 4 infections, 1 dislocation and 1 aseptic loosening). The 10-year survival was 98% (44 at risk in 10th year). One patient sustained a periprosthetic fracture at 3 weeks, treated with buttress plate fixation. Discussion. This is the first detailed series reporting the long-term outcome of the cementless Oxford mUKA implanted using microplasty instrumentation. There was a low failure rate, with only one revision for aseptic loosening. Lateral progression was the commonest cause for revision, with an incidence of 1%. This report provides evidence that the combination of evidence-based indications, well-designed instrumentation and cementless fixation can provide excellent long-term survival for the Oxford mUKA in treating AMOA


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_I | Pages 29 - 29
1 Jan 2003
Price A Svard U
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To report a 15-year survival analysis of the Oxford Medial Unicompartmental Knee Arthroplasty (Oxford UKA) in an independent series. We report the results of a series of 420 Oxford UKAs performed between 1983 and 2000. Indications for surgery were primary antero-medial osteoarthritis of the knee with an intact ACL, correctable varus deformity of < 15° and < 15° fixed flexion deformity. The state of the patello-femoral joint was not used as a selection criterion. Patients were contacted by a postal questionnaire or by telephone. The outcome of all 420 knees was established, with none lost to follow-up. Seventy-six knees were in patients who had died and the state of each arthroplasty was determined from hospital and GP records. Seventeen patients (4%) had required revision. Indications for revision were lateral compartment arthrosis (7), component loosening (4), bearing dislocation (4) and infection (2). There were no failures for polyethylene wear. Cumulative survival at 15 years was 94.3% [95% CI 3.8%]. The worst case scenario was 94.3% as none were lost to follow-up. The results from an independent series are important, as they avoid bias. The 15-year results of this independent series are better than any other reported series of unicompartmental device at 15 years and as good as the published independent 15 year survival results for total knee arthroplasty. The data illustrates that excellent long-term survival can be achieved with the Oxford UKA, allowing patients to benefit from the advantages that unicompartmental arthroplasty offers. We believe that provided patients are selected appropriately, this device provides the treatment of choice for anteromedial osteoarthritis of the knee


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_6 | Pages 33 - 33
1 Apr 2018
Song M Kim Y Yoo S Kang S Kwack C
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Purpose. Unicompartmental Knee Arthroplasty (UKA) has been indicated for inactive elderly patients over 60, but for young and active patients less than 60 years old, it has been regarded as a contraindication. The purpose of this study is to evaluate the usefulness of UKA performed on young Asian patients under 60 years of age by analyzing clinical outcomes, complications and survival rate. Materials and Methods. The subjects were 82 cases, which were followed up for at least 5 years (from 5 to 12 years). Only Oxford phase III® (Biomet Orthopedics, Inc, Warsaw, USA) prosthesis was used for all cases. The clinical evaluation was done by the range of motion, Knee society score (KSS), WOMAC score. The radiographic evaluation was performed on weight bearing long-leg radiographs, AP and lateral view of the knee and skyline view of the patella. The survival rate was estimated by Kaplan-Meier survival analysis. Results. Three bearing dislocations, one medial tibial collapse and one lateral osteoarthritis occurred, so the complication rate was 6.1% (5/82). Among the 3 cases of bearing dislocation, 2 cases were resolved by replacing with a thicker bearing and 1 case was converted to TKA due to repeated dislocation. One case of medial tibia collapse and one lateral osteoarthritis were converted to total knee arthroplasty (TKA). All clinical outcomes measured by KSS scores and WOMAC score showed a statistically significant difference (p<0.001). The 10 year cumulative survival rate using Kaplan-Meier survival method was 94.7% (95% CI: 88.7%–100%). Conclusion. The clinical outcomes and the survival rate of young asian patients less than 60 years of age who underwent Oxford medial UKA showed good clinical results and a good survival rate in the mid-term results. However, long-term follow-up is needed for more reliable clinical results


Orthopaedic Proceedings
Vol. 85-B, Issue SUPP_I | Pages 52 - 52
1 Jan 2003
Price AJ Svard U
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The purpose of this study was to establish the long-term clinical outcome of the Oxford Medial Unicompartmental Knee Arthroplasty (UKA). Methods: A continuous series of 420 patients underwent medial Oxford UKA. Indications were anteromedial osteoarthritis with full thickness lateral compartment cartilage, a functioning anterior cruciate ligament and correctable varus deformity. Survival analysis with all cause revision as the endpoint was carried out for the entire group. At the time of this study 121 were still alive at 10 years and pre/post-operative 10-year clinical data had been prospectively recorded for them from which the AKS and HSS scores were calculated. Results: Seventeen patients required revision (4%) and the fifteen year survival rate was 94.3% (95% CI 85.6 - 100%). At ten years AKS and HSS scores were: AKSS (Knee) pre 30 / post 90, AKSS (Function): pre 42/ post 69 and HSS pre 56/ post 86. The differences were statistically significant (p< 0.01). Discussion and Conclusion: We conclude that providing careful patient selection is maintained, meniscal bearing medial unicompartmental knee arthroplasty has clinical and survival results comparable to modern total knee arthroplasty. The advantages of lower morbidity and earlier return to function, enhanced by the introduction of minimally invasive techniques may make this the treatment of choice for suitable patients with anteromedial osteoarthritis of the knee


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IX | Pages 33 - 33
1 Mar 2012
Pennington R Naik L Diab D Allen P
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The purpose of the study was to investigate the outcome of Oxford medial unicompartmental knee replacement (UKR) in patients over 70 years old and also to assess their ability to kneel. We identified from our prospectively collected knee database 90 patients (98 knees) undergoing Oxford medial UKR who were 70 years or older on the day of surgery. Oxford Knee Scores (OKS) were collected pre-operatively and also post-operatively at the following intervals: 3 months, 6 months, 1 year, 2 years, 5 years and then annually after this. The mean patient age at surgery was 73.2 years (range 70.2 – 84.3 years). The OKS pre-operatively had a mean of 35.8/60 (range 22-55) and improved to 23.6/60 post-operatively (range 14-34). Patient follow-up was 44.3 months and ranged from 12-111 months. Two patients were lost to follow-up, 1 was converted to a total knee replacement and 3 died of causes unrelated to the knee surgery. 91.7% of patients still had their original prostheses at last follow-up. Forty percent of patients stated they were able to kneel pre-operatively which improved to 50.2% postoperatively. This was consistent throughout all the follow up intervals that were assessed. Specific kneeling score from the OKS showed no statistically significant change with a mean of 3.94/5 pre-operatively and a mean of 3.54 averaged over all the post-operative follow up intervals. We conclude that medial Oxford UKR is a reliable operation in patients over 70 years old. Previous studies include a younger age group which potentially encourages the less familiar surgeon to use a UKR for the young active patient but continue with a total knee arthroplasty for the older patient. Our study suggests age should not be a factor when considering performing Oxford UKR. Ability to kneel is not altered significantly by UKR in this age group


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_I | Pages 117 - 117
1 Mar 2010
Choy W Kim K Ko J
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Purpose: To analyze the clinical and radiographic results of patients treated by Oxford minimally invasive unicompartmental knee arthroplasty.

Materials and Methods: We have operated 166 patients 188 knees of minimally invasive unicompartmental knee arthroplasty(Oxford Uni®) from January 2002 to December 2005. The mean ages was 65.3 (44–82) years and 16 cases of male and 150 cases of female. The mean follow-up period was 57 (36–77) months. Preoperative diagnosis were osteoarthritis in 166 cases, avascular necrosis of medial femoral condyle in 20 cases and chondrocalcinosis in 2 cases. The clinical results were evaluated using the HSS knee score and the range of motion of knee preoperatively and at the final follow up. At the final follow up, the ability of the patient to assume the squatting and cross-leg position were checked. The tibiofemoral angle was measured preoperatively and postoperatively. Component loosening, radiolucent lines were checked.

Result: The HSS knee score was 67.5 (52–86) preoperatively and 89.9 (59–100) at the final follow up. The mean preoperative flexion contracture was 6.5° (0–20) and 0.81 (0–5) at the final follow up. Active full flexion was possible within postoperative 2 months. The squatting position was possible in 133 patients (80.1%) and the cross-leg position was possible in 152 patients (91.6%). The tibiofemoral angle was improved varus 1.5° to valgus 4.8°. Complication occurred in 14 cases (7.4%). Meniscal bearing dislocation in 8 cases (4.3%). Tibial components loosenig in 3 cases (1.6%). Femoral components loosening in 2 cases (1.1%). The average time of meniscal bearing dislocation was 11.3 (3–24)months postoperatively. Six cases returned to the predislocation level of activity with the insertion of thicker bearings and 2cases required TKR conversion.

Conclusion: Minimally invasive unicompartmental knee arthroplasty(Oxford Uni®) provides rapid recovery, good pain relief and excellent function quite suitable to Korean life-style. But given the high complicate rate in mid-term results. Oxford Uni® gives less reliability compared with TKR.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVII | Pages 189 - 189
1 Sep 2012
Matharu G Robb C Baloch K Pynsent P
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Background

Unicompartmental knee arthroplasty provides a good alternative to total knee arthroplasty in patients with isolated medial compartment osteoarthritis. There has been variable reporting in the literature as to whether age and sex affect the survival of unicompartmental knee arthroplasty. The aim of this study was to determine whether age and sex were predictors of failure for the Oxford unicompartmental knee arthroplasty.

Methods

Details of consecutive patients undergoing Oxford unicompartmental knee arthroplasty at our centre between January 2000 and December 2009 were collected prospectively. Failure of the implant was defined as conversion to total knee arthroplasty. Survival was determined using the Kaplan-Meier method. A Cox proportional hazard model was used to determine the affect of age and sex on survivorship of the prosthesis.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIX | Pages 28 - 28
1 Jul 2012
Matharu G Robb C Baloch K Pynsent P
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Background

Unicompartmental knee arthroplasty provides a good alternative to total knee arthroplasty in patients with isolated medial compartment osteoarthritis. There has been variable reporting in the literature as to whether age and sex affect the survival of unicompartmental knee arthroplasty.

Study aims

The aims of this study were to determine whether age and sex were predictors of failure for the Oxford unicompartmental knee arthroplasty.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_II | Pages 131 - 131
1 May 2011
Labek G Sekyra K Pawelka W Janda W Agreiter M Schlichtherle R Stöckl B Krismer M
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Background: Within the scope of the EU project EUPHORIC a methodology for direct comparison of different datasets was developed and applied on a sample of implants, among them the Oxford Unicompartmental Knee Arthroplasty (Oxford Uni). The aim was to identify potential bias factors inherent in the datasets and evaluate the outcome achieved with this implant.

Materials and Methods: A structured comparison was performed of data published on the revision rate of the Oxford Unicompartmental prosthesis. Both clinical follow-up studies published in Medline-listed journals and worldwide Register data were included. The data were stratified with regard to potential influence factors like the individual research groups or the geographical origin of the papers.

Results: A major proportion of the published data, between 50 and 75%, depending on the method of calculation, comes from studies including the developing institution in Oxford. The results published by this group deviates statistically significantly from the reference datasets from Register data or independent research groups. Data from the developing hospital show mean revision rates that are 4.4 times lower than those based on worldwide Register data, and 2.74 times lower than in independent studies. As opposed to this, independent studies on average publish data that are reproducible in Register data.

Conclusion: A conventional meta-analysis of clinical studies is significantly affected through the influence of the developing institution and is therefore subject to a bias. Neither through arthroplasty Register outcome data nor by other research groups that have disclosed outcome information on the Oxford Uni can the excellent results be reproduced that were published by the inventors.

Compared to other implants for unicompartmental knee arthroplasty in worldwide arthroplasty Registers, the Oxford Uni shows good results.

For the assessment of the outcome of implants, register data are to be rated superior and, in terms of reference data for the detection of potential bias factors in the clinical literature, can provide an essential contribution for scientific meta-analyses.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXV | Pages 215 - 215
1 Jun 2012
Shetty G Mullaji A
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Excessive under correction of varus deformity may lead to early failure and overcorrection may cause progressive degeneration of the lateral compartment following medial unicompartmental knee arthroplasty (UKA). However, what influences the postoperative limb alignment in UKA is still not clear. This study aimed to evaluate postoperative limb alignment in minimally-invasive Oxford medial UKAs and the influence of factors such as preoperative limb alignment, insert thickness, age, BMI, gender and surgeon's experience on postoperative limb alignment.

Clinical and radiographic data of 122 consecutive minimally-invasive Oxford phase 3 medial unicompartmental knee arthroplasties (UKAs) performed in 109 patients by a single surgeon was analysed. Ninety-four limbs had a preoperative hip-knee-ankle (HKA) angle between 170°-180° and 28 limbs (23%) had a preoperative hip-knee-ankle (HKA) angle <170°. The mean preoperative HKA angle of 172.6±3.1° changed to 177.1±2.8° postoperatively. For a surgical goal of achieving 3° varus limb alignment (HKA angle=177°) postoperatively, 25% of limbs had an HKA angle >3° of 177° and 11% of limbs were left overcorrected (>180°). Preoperative HKA angle had a strong correlation (r=0.53) with postoperative HKA angle whereas insert thickness, age, BMI, gender and surgeon's experience had no influence on the postoperative limb alignment.

Minimally invasive Oxford phase 3 UKA can restore the limb alignment within acceptable limits in majority of cases. Preoperative limb alignment may be the only factor which influences postoperative alignment in minimally-invasive Oxford medial UKAs. Although the degree of correction achieved postoperatively from the preoperative deformity was greater in limbs with more severe preoperative varus deformity, these knees tend to remain in more varus or under corrected postoperatively. Overcorrection was more in knees with lesser preoperative deformity. Hence enough bone may need to be resected from the tibia in knees with lesser preoperative deformity to avoid overcorrection whereas limbs with large preoperative varus deformities may remain under corrected.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 430 - 431
1 Nov 2011
Tada M Inui K Yoshida H Takei S Fukuoka S Matsui Y Yoshida K
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Good mid-term results of Oxford UKA (OxUNI) for anteromedial osteoarthritis (OA) were reported. The designers of prosthesis reported a 98% 10-year survival rate for a combined series of phase I and II, and these findings were supported by published results from other series, with 10-year survival ranging from 91% to 98%. In order to obtain good results, the designers of this prosthesis mentioned the importance of adhering to strict indication for OxUNI, especially only for OA cases with intact anterior cruciate ligament (ACL). OxUNI combined with ACL reconstruction (ACLR) is a viable treatment option for only young active patients, in whom the ACL has been primarily ruptured. On the other hand, it was not clear whether the result of OxUNI combined with ACLR for OA with secondary ruptured ACL was good. In this study we compare the short-term results of OxUNI combined with ACLR for OA with secondary ruptured ACL with that for usual OA with intact ACL.

382 OxUNI were performed at two hospitals by one surgeon between January 2002 and August 2005. Among those, 367 cases, followed over two years postoperatively (272 patients, women: 283, men: 84) were assessed. Follow up ratio was 96.1%. The mean patient age at the time of surgery was 72.0 (47~93) years. The mean follow-up period was 39.3 (24~67) months. Thirty three knees of OA were treated with OxUNI combined with ACLR, by using synthetic graft. Clinical results were assessed by the Oxford Knee Score (OKS) and active range of motion (ROM). Patients are asked a series of 12 questions, and their response scores range from 0 (worse) to 4 (best) for each, yielding an overall score range of 0–48. All living patients were contacted, and the status of the implant was established at the time of last follow from hospital records. We evaluate the survival rate for OxUNI with or without ACLR, using the endpoint of revision for any reason.

The pre-and postoperative clinical scores were compared using the paired Student’s t-test. Survivor-ship curves were constructed using the Kaplan-Meier method, and survivorship between groups was compared using logrank and Wilcoxon methods. All analyses were performed using 95% confidence intervals and a P value of < 0.05 was considered significant.

The mean OKS at final follow-up was 42.1 (preoperative; 21.7), and the mean active ROM was 125.2° (preoperative; 113.4°). OKS and active ROM were significantly improved. There were no significant differences in OKS and active ROM between OxUNI with ACLR and OxUNI with intact ACL. Fourteen knees among 367 knees were revised; nine for loosening of tibial component, four for dislocation of bearing and one for progression of lateral OA. Overall 5-year survival rate was 95.6%. When survival rate was assessed separately with or without ACLR, that of OxUNI with intact ACL was 96.7% and that of OxUNI with ACLR was 83.8%. There was significant worse survival rate between the two groups (P=0.0071).

The 5-year survival rate for OxUNI with intact ACL was 96.7%, which was equivalent to those of original series from Oxford. However, 5-year survival rate for Oxford UKA with ACLR was 83.8% in our series. Four knees in nine of loosening of tibial component were replaced by OxUNI combined with ACLR. Therefore, even if ACL was reconstructed, the results of OxUNI for OA with secondary ruptured ACL was proved to be pessimistic.

There was significantly worse survival rate for OxUNI with ACLR, compared with OxUNI with intact ACL. So we conclude that combined ACL reconstruction and OxUNI for anteromedial OA with secondary ruptured ACL is not recommended, which must be treated with TKA.


Orthopaedic Proceedings
Vol. 102-B, Issue SUPP_8 | Pages 25 - 25
1 Aug 2020
Salimian A Howatt J Dervin G Kim P
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The Oxford mobile bearing knee prosthesis (Zimmer Biomet Inc, Warsaw, Ind) is considered a good treatment option for isolated medial compartment knee arthrosis. From February 2001 until August 2016, 1719 primary Oxford medial unicompartmental knee replacement procedures were completed at our center by a group of seven surgeons. We undertook this study to examine the long-term survivorship of the Oxford unicompartmental knee replacement looking at survivorship and reasons for failure. A retrospective consecutive case series review was completed, and all revisions and re-operations were identified. Conversion to total knee replacement (TKA) was considered a failure. Kaplan-Meier survival analysis was used to calculate the 15-year survivorship of the group overall. We specifically looked at age, gender, BMI and surgeon caseload in addition to the reasons for failure. A statistical analysis was performed and differences in survivorship were compared for the variables listed. A logistic cox regression was performed to explore predictors of revision. Overall 15-year survivorship was 89.9%. Female survivorship of 88.1% was statistically worse than the male group at 91.8% (p=0.018). Younger patients (75yrs of age (p= 0.036). There was a large range in surgical case load by individual surgeons (range 17–570 knees). There were no statistically significant differences in age, BMI, or gender when comparing the individual surgeon groups. There was a large range in 15-year survivorship between individual surgeons (range 78.3% – 95%). Overall the most common reason for revision was due to wear of the unreplaced portion of the knee (lateral and/or patella-femoral joint) followed by aseptic loosening, polyethylene dislocation, infection or persistent pain. The 15-year survivorship results of the Oxford medial unicompartmental knee replacement at our center compares favourably to other published series and large registry data series. We found a reduction in survivorship in female patients and younger patients (< 5 5yrs). There were also significant differences in survivorship based on the individual surgeon. A more selective patient approach yielded the best long-term survivorship and equivalent to that of total knee replacement. We therefore suggest using a more selective approach when choosing patients for a medial unicompartmental knee replacement with the Oxford mobile bearing prosthesis in order to enhance long-term survivorship


Orthopaedic Proceedings
Vol. 105-B, Issue SUPP_13 | Pages 57 - 57
7 Aug 2023
Gill J Brimm D McMeniman P McMeniman T Myers P
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Abstract. Introduction. Patient selection is key to the success of medial unicondylar knee arthroplasty (UKA). Progression of arthritis is the most common indication for revision. Various methods of assessing the lateral compartment have been used including stress radiography, radioisotope bone scanning, MRI, and visualisation at the time of surgery. Arthroscopy is another means of assessing the integrity of the lateral compartment. Methods. We used per-operative arthroscopy as a means to confirm suitability for UKA in a consecutive series of 279 Oxford medial UKA. This study reports the long-term results of a previously published cohort of knees. Our series of UKA with per-operative arthroscopy (Group 1) was compared to all Oxford UKA (Group 2) and all UKA in the Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR) (Group 3). Results. The 14-year cumulative percentage revision (CPR) was 18.5% (95% CI 12.7, 26.4) for group 1, 19.7% (95% CI 18.8, 20.6) for group 2, and 19.2% (95% CI 18.5, 19.8) for group 3. There was no statistically significant difference in the (CPR) for the entire period when group 1 was compared to groups 2 or 3. Progression of arthritis was the indication for revision in similar proportions for the three groups (Group 1: 32.3%, Group 2: 35.7% and Group 3: 33.5%). Following per-operative arthroscopy 21.6% (77/356) of knees underwent a change of surgical plan from UKA to TKA. Conclusion. Per-operative arthroscopy may improve medium-term medial unicompartmental knee survivorship but does not improve long-term survivorship nor reduce revision due to progression of arthritis


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 101 - 101
1 Mar 2006
Langdown A Pandit H Price A Dodd CAF Murray D Svoerd Gibbons C
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Introduction This study assesses the outcome of medial unicompartmental knee arthroplasty (UKA) using the Oxford prosthesis for end-stage focal spontaneous osteonecrosis of the knee (SONK, Ahlback grades III & IV). Methods A total of 29 knees (27 patients) with SONK were assessed using the Oxford Knee Score. Twenty-six had osteonecrosis of the medial femoral condyle; 3 had osteonecrosis of the medial tibial plateau. This group was compared to a similar group who had undergone Oxford Medial UKA for primary osteoarthritis. Patients were matched for age, sex and time since operation. Results Mean length of follow-up was 5.2 years (range 1–13 years). There were no implant failures in either group, but there was one death 9 months post-arthroplasty from unrelated causes in the group with osteonecrosis. The mean Oxford Knee Score (SD) in the group with osteonecrosis was 37.8 (7.6) and 40.0 (6.6) in the group with osteoarthritis. There was no significant difference between the two groups using Student’s t-test (p=0.29). Interpretation Use of the Oxford Medial UKA for focal spontaneous osteonecrosis of the knee is reliable in the short to medium term, and gives similar results to when used for patients with primary osteoarthritis


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXVI | Pages 48 - 48
1 Aug 2012
Sarkar S Divekar M
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Study of failed Oxford medial unicompartmental knee replacements at the Royal Cornwall Hospital. Objective. we set up a retrospective study to identify the various reasons for failure of oxford medial unicompartmental knee replacements and to assess their outcome following revision. Materials and Method. Over 5 years (2006- 2010) we identified 26 failed unicompartmental knee replacements, which were revised at the Royal Cornwall hospital. We retrospectively analysed the data to include pre-operative and post-operative Oxford score, range of movement, patient satisfaction and the type of implant used. Results. There were 9 males and 17 females in our series with an average age of 65 years (49 to 80). The average follow up was 2.6 years (1 - 4.6 years). The pre-revision Oxford score was 21.3 (12 to 35), which improved to 41.7 (18 to 47) following surgery. Almost all patients benefited with increase in the range of movement. The implants were revised at an average duration of 4 years and 8 months (1 to 17 yrs) following the index operation. The commonest cause of failure was progression of arthritis in the lateral compartment 50 % (13/26), revision for unexplained pain 23 % (6/26) and aseptic loosening 23 % (6/26). There was one case of sepsis 4 % (1/26). We did not come across dislocation of the bearing. The implants were revised using primary or complex primary knee systems. The infected knee was revised using a two-stage technique. Conclusion. Unicompartmental knee replacement is a successful procedure for treating isolated medial compartment arthritis. Commonest indication for revision in our study was progression of arthritis in the lateral compartment. Revision is relatively easy and results of revision are good with high patient satisfaction. Our results are comparable to published data from larger centres


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXI | Pages 119 - 119
1 May 2012
G. M C. R K. B P. P
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Background. Unicompartmental knee arthroplasty provides a good alternative to total knee arthroplasty in patients with isolated medial compartment osteoarthritis. Reported ten-year survival for the Oxford medial unicompartmental knee arthroplasty is variable, ranging from 80.2% to 97.7% in the originator series. The aim of this study was to determine the survival and reasons for revision of the Oxford medial unicompartmental knee arthroplasty when performed at a specialist orthopaedic centre. Methods. Details of consecutive patients undergoing Oxford unicompartmental knee arthroplasty at our centre between January 2000 and December 2009 were collected prospectively. Failure of the implant was defined as conversion to total knee arthroplasty. Survival was determined using the Kaplan-Meier method. Results. There were 494 Oxford unicompartmental knee arthroplasties implanted in 425 patients for isolated medial compartment osteoarthritis. Mean age was 62.8 yrs (range 34.6-90.1 yrs) and 53.4% were female. During a mean follow-up time of 3.0 yrs (range 0.5-9.2 yrs), twenty-two knees (4.5%) were revised to a total knee arthroplasty. Reasons for revision were aseptic loosening of the femoral (n=8) or tibial component (n=2), undiagnosed pain (n=5), patellofemoral pain (n=2), infection (n=1), lateral meniscus tear (n=1), periprosthetic fracture (n=1), joint instability (n=1), and dislocation of meniscal bearing (n=1). Mean time to revision surgery from the primary procedure was 3.0 yrs. Eight-year survival for the cohort was 87.4%. The median pre-operative Oxford knee score was 62.5% which reduced to 27.7% at four years post-operatively. Conclusion. This study has demonstrated our revision rate for the Oxford unicompartmental knee replacement is comparable to independent series and national registry data. Post-operative function in patients not revised was good. The commonest reason for failure was aseptic component loosening which usually occurred within two to four years. Extended follow-up may therefore be beneficial in these patients so these cases are identified early and subsequently revised


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_II | Pages 258 - 258
1 May 2006
Langdown AJ Pandit H Price AJ Dodd CAF Murray DW Svärd UCG Gibbons CLMH
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Introduction: This study assesses the outcome of medial unicompartmental knee arthroplasty (UKA) using the Oxford prosthesis for end-stage focal spontaneous osteonecrosis of the knee (SONK, Ahlback grades III & IV). Methods: A total of 29 knees (27 patients) with SONK were assessed using the Oxford Knee Score. Twenty-six had osteonecrosis of the medial femoral condyle; 3 had osteonecrosis of the medial tibial plateau. This group was compared to a similar group who had undergone Oxford Medial UKA for primary osteoarthritis. Patients were matched for age, sex and time since operation. Results: Mean length of follow-up was 5.2 years (range 1–13 years). There were no implant failures in either group, but there was one death 9 months post-arthroplasty from unrelated causes in the group with osteonecrosis. The mean Oxford Knee Score in the group with osteonecrosis was 37.8 (± 7.6) and 40.0 (± 6.6) in the group with osteoarthritis. There was no significant difference between the two groups using Student’s t-test (p=0.31). Interpretation: Use of the Oxford Medial UKA for focal spontaneous osteonecrosis of the knee is reliable in the short to medium term, and gives similar results to when used for patients with primary osteoarthritis


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXIII | Pages 12 - 12
1 Jul 2012
Waterson H Brenkel I Cook R
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The Oxford medial unicompartmental knee replacement has been shown to provide good long-tern results in numerous studies with survivorship at 10 years ranging from 82% to 100%. This prospective study describes the survival of 265 Oxford unicompartmental knee replacements implanted in one centre from 1995-2009. 8 were lost to follow up. 40 of the 265 knees were revised. For operation performed from1995-1999 the risk of revision at 5 years was 10%, operations from 2000-2004 the risk of revision was 15% and from 2005-2009 the risk of revision at 5 years was 36%. This study demonstrates that since 2005 there has been a significant increase in early failure of the Oxford unicompartmental knee at this institution and discusses the possible reasons for this


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 180 - 180
1 Mar 2008
Pandit H Jenkins C Beard D Gill HS McLardy-Smith P Dodd C Murray D
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Oxford Unicompartmental knee arthroplasty (UKA) is now performed using a minimally invasive surgical (MIS) technique. Although early results are encouraging, the studies assessing outcome could be criticised for the restricted number of patients and limited follow-up. Aim of this study was to assess clinical outcome and prosthetic survival rate inpatients with minimally invasive Oxford medial UKA. This prospective study assessed 500 consecutive patients, who underwent cemented Oxford UKA for medial OA using MIS technique. Patients were assessed using objective and functional Knee Society Score (KSS). This study has confirmed preliminary findings that Oxford UKA using a minimally invasive approach is safe, reliable and effective