Aims. The aim of this study was to compare the effectiveness of a femoral nerve block and a periarticular infiltration in the management of early post-operative pain after total knee arthroplasty (TKA). Patients and Methods. A pragmatic, single centre, two arm parallel group, patient blinded, randomised controlled trial was undertaken. All patients due for TKA were eligible. Exclusion criteria included contraindications to the medications involved in the study and patients with a neurological abnormality of the lower limb. Patients received either a femoral nerve block with 75 mg of 0.25% levobupivacaine hydrochloride around the nerve, or periarticular infiltration with 150 mg of 0.25% levobupivacaine hydrochloride, 10 mg morphine sulphate, 30 mg ketorolac trometamol and 0.25 mg of adrenaline all diluted with 0.9% saline to make a volume of 150 ml. Results. A total of 264 patients were recruited and data from 230 (88%) were available for the primary analysis. Intention-to-treat analysis of the primary outcome measure of a visual analogue score for pain on the first post-operative day, prior to physiotherapy, was similar in both groups. The mean difference was -0.7 (95% confidence interval (CI) -5.9 to 4.5; p = 0.834). The periarticular group used less morphine in the first post-operative day compared with the femoral nerve block group (74%, 95% CI 55 to 99). The femoral nerve block group reported 39 adverse events, of which 27 were serious, in 31 patients and the periarticular group reported 51 adverse events, of which 38 were serious, in 42 patients up to six weeks post-operatively. None of the adverse events were directly attributed to either of the interventions under investigation. Conclusion . Periarticular infiltration is a viable and safe alternative to femoral nerve block for the early post-operative relief of pain following TKA. Cite this article: Bone Joint J 2017;99-B:904–11

Objective: The aim of this prospective observational study was to evaluate the feasibility of performing ACL reconstruction with femoral nerve block as a day-case procedure, implement the necessary changes and audit the outcomes following instigation of a day-case protocol. Methods: From November 2005 to April 2006 all patients undergoing ACL reconstruction were entered into a day-case feasibility study. Any issues preventing day-case discharge were identified, and in November 2006 changes were implemented to address these. Since then all ACL reconstruction patients have been treated as day-cases using femoral nerve blocks. Patients are discharged if safe, and contacted 1 and 7 days postoperatively to detect any problems and to assess patient satisfaction. Patients undergoing ACL reconstruction with femoral nerve block in the independent sector, by the same surgeon but without a strict protocol were used as a comparison group. Results: 18 patients have followed the day-case pathway, 15 (83%) being discharged as day-cases. The other cases had afternoon surgery delaying discharge. Only 25% (3/12) patients treated in the independent sector were discharged on the day of surgery. All patients had good working femoral nerve blocks, were able to mobilise safely with crutches and reported no adverse effects from their blocks at follow-up phone calls. All reported good analgesia at home and high satisfaction with being a day-case. Conclusions: With appropriate education of patients and staff, and following a day-case protocol, ACL reconstruction with femoral nerve block is a safe day-case procedure with high patient satisfaction

Femoral nerve block is a reliable and effective method of providing anaesthesia and analgesia in the peri-operative period but there remains a small but serious risk of neurological complication. We aimed to determine incidence and outcome of neurological complications following femoral nerve block in patients who had major knee surgery. During the period January 2003 to August 2008, medical records of all patients undergoing knee surgery by Dr Myles Coolican and Dr David Parker, who had been administered femoral block for peri-operative analgesia, were evaluated. Patients with a neurological complication were invited take part in the study. A detailed physical examination including sensory responses, motor response and reflexes in both limbs was performed by an independent orthopaedic surgeon. Subjective outcome and pain specific questionnaires as well as clinical measurements were also collected. Out of 1393 patients administered with femoral nerve block anaesthesia during this period, 28 subjects (M:F= 5:23) were identified on the basis of persistent symptoms (more than three months) of femoral nerve dysfunction. All the patients had sensory dysfunction in the autonomous zone of femoral nerve sensory distribution. The incidence of neurological complications was 2.01%. One patient was deceased of unrelated causes and five patients declined to participate in the study. 14 patients out of the 22 have been examined so far. Nine cases had a one shot nerve block and five had continuous peripheral nerve block catheter. Areas of hypoesthesia/anaesthesia involving femoral nerve distribution occurred in 7 subjects and hyperaesthesia/paresthesia occurred in four. One subject had a combination of hypoesthesia and hyperesthesia in different areas of the femoral nerve distribution. Three subjects had bilateral symptoms following bilateral simultaneous nerve blocks. Dysesthesias in the affected dermatomes were found in seven cases and paresthesias were found in eight cases. Douleur Neuropathique en 4 questions (DN4) score of ï. 3. 4 was found in all the patients (average value: 5.55). The average scores for tingling, pins and needles and burning sensation (in a scale from 0 to 10) are 3.8, 3.1 and 2.9 respectively. The incidence of persistent neurological complication after femoral nerve block in our series is much higher compared to the reported incidence in the contemporary literature (Auroy Y. et al. Major complications of regional anesthesia in France: Anesthesiology 2002; 97:1274 80). The symptoms significantly influence the quality of life in the affected cases and question the value of the femoral nerve block in knee surgery

Objective: The aim of this prospective observational study was to evaluate the feasibility of performing ACL reconstruction with femoral nerve block as a day-case procedure, implement this change and audit our outcomes. Methods: From November 2005 to April 2006 all patients undergoing ACL reconstruction were entered into a day-case feasibility study. Any issues preventing day-case discharge were identified, and in November 2006 changes were implemented to address these. Since then all ACL reconstruction patients have been treated as day-cases using femoral nerve blocks. Patients are discharged if safe, and contacted 1 and 7 days postoperatively to detect any problems and to assess patient satisfaction. Results: 23 patients have followed the day-case pathway, 15 being discharged as day-cases. The other cases had afternoon surgery delaying discharge or surgery in the independent sector where the protocol was not enforced. All patients had good working femoral nerve blocks, were able to mobilise safely and easily with crutches and reported no adverse effects from their blocks at follow-up phone calls. All reported good analgesia at home and high satisfaction with being a day-case. Conclusions – With appropriate education of patients and staff, ACL reconstruction with femoral nerve block is a safe day-case procedure with high patient satisfaction

Objectives. The goal of this retrospective study was to compare two different processes of pain control after total knee arthroplasty (TKA): local anesthesia versus femoral nerve block. The tested hypothesis was that the patient's ability to be discharged was obtained sooner with the local anesthesia process. Methods. 110 patients consecutively operated on for TKA by a single surgeon without any selection criterion were included. The study group included 58 patients operated on under general anesthesia with infiltration of the surgical field with local anesthesia. The control group included 52 patients operated on under general anesthesia and continuous femoral nerve block. In the study group, 200 ml of ropivacaïne 5% were injected into the surgical field, and an intra-articular catheter was left to allow continuous infusion of ropivacaïne (20 ml/h during 24 hours). The control group was treated by a femoral nerve block with ropivacaïne during 24 hours. Discharge was considered allowed when the patient was able to walk independently, go upstairs and downstairs independently, when the knee flexed over 90° and if the subjective pain assessment (VAS) was under 3/10. Results. Discharge allowance was obtained sooner (mean 2 days) in the study group (p<0.01). 40 patients of the study group (69%) and 2 patients of the control group (4%) were able to stand up on the day of implantation (p<0.001). Deambulation was possible at D1 in the study group and D2 in the control group (p<0.001). Gait was possible at D4 in the study group and D6 in the control group (p<0.05). Discharge was possible 2 days earlier in the study group (p<0.01). Active quadriceps function was recovered 2 days earlier in the study group (p<0.001). Knee flexion exceeded 90° 2 days earlier in the study group (p<0.001). There was a faster decrease of the pain VAS in the study group, but the total consumption of analgesic was not different in the two groups. The complication rate was not different in the two groups. Conclusion. The process using local anesthesia may allow a better pain control after TKA, and consequently a faster rehabilitation and an earlier discharge

We performed a randomized feasibility trial to examine the impact of preoperative femoral nerve block (FNB) on elderly patients with hip fractures, including those with mild to moderate cognitive impairment. We evaluated the impact of preoperative FNB on the following outcomes within 5 days of surgical fixation: 1. Pain levels, 2. Total narcotic consumption, 3. Postoperative mobilization. Randomized allocation of 73 patients in a 2:1 intervention:control ratio. To allow comparison between the 2 groups as well as sub- analysis of the intervention group to examine treatment fidelity (i.e. the ability to deliver the intervention as planned). Inclusion criteria: Patient age≥ 65 years admitted with a low energy hip fracture, ambulatory preinjury, Mini Mental State Exam MMSE score≥13 (moderate dementia), Able to provide direct or proxy consent. Exclusion criteria: Admission ≥ 30 hours after injury, prior regular use of opiates. Potential participants were identified and either participants or proxy respondents provided signed informed consent. Participants allocated to the intervention group received a FNB administered by the UAH acute pain service (APS) within 20 hours of admission to hospital in addition to the usual care. Participants in the control group received usual care. Participants were followed for 5 days postoperatively with daily assessment of pain, narcotic consumption, delirium and mobility. Main outcome measure: (1) Pain at rest and activity (2) Preoperative and postoperative opioid consumption, (3) Mobilization in POD#1. Overall, 73 participants were enrolled (23 Control: 50 FNB). The FNB group was slightly older (mean [SD] 80.1 [8.7] vs. 76.2 [9.2], p=0.09) and had more males (21 [42%] vs. 5 [22%], p=0.09) than the Control group. The mean MMSE score for both groups was >24 (p=0.35 for group comparison), suggesting minimal cognitive impairment of participants. The FNB group reported significantly less pain at rest and activity than the control group over time (p < 0 .001 for both). Opioid consumption were non-significantly higher and more variable in the control group preoperatively (Median [25, 75 quartile] 10.6 [0, 398] vs 7.5 [0, 125], p=0.26) and postoperatively (13.1 [0, 950] vs 10 [0, 260], p=0.31). 41 (85%) of FNB participants mobilized on day 1 vs. 16 (73%) of control participants (p=0.21). Preoperative FNB significantly reduced pain. Opioid consumption was not significantly different, but more variable in the control group. Although not significant, more FNB patients successfully mobilized on day 1 postoperatively. Participants with cognitive impairment were not enrolled due to difficulty in obtaining proxy consent. A definitive randomized trial would be feasible and add valuable information about pain management following hip fracture

Introduction: Inadequate control of postoperative pain after total knee arthroplasty (TKA) has been associated with a poor functional recovery. This study investigated whether the addition of a single injection femoral nerve block (FNB) to continuous epidural analgesia (EA) provides improved pain control, lowered side effects, and a further acceleration in achievement of rehabilitation goals. Material and methods: Eighty patients undergoing TKA and receiving EA with 18 ml of 0.5% marcaine were randomized whether to receive or not a single dose of FNB. A nerve stimulator and 30 ml of 0.375% marcaine with 5 μg/ml of epinephrine were used to perform FNB prior to surgery. Post-operative continuous EA was self-administered by the patient adding bolus (up to 4bolus/hour) to the basal infusion rate of 2 ml/hour of 0.175% marcaine. Standardized post-operative rehabilitation protocol were followed for both groups. Therapists and clinicians were blinded to treatment group. Overall narcotic consumption, bolus dosing, and side effects were recorded. Outcomes measurements included postoperative strength and sensation, range of motion and progression, pain score (VAS), achievements of functional milestones and length of stay. Results: Femoral nerve block group had significantly lower pain scores and lower epidural consumption in comparison to the group without block (p< 0.01). Range-of-motion was significantly greater through post-operative day three in the FNB group (p< 0.04). There was a consistent trend toward improved achievements in rehabilitation milestones after FNB. Decreased quadriceps strength was noted in 33% of the FNB patients on post-operative day one compared to 10% of the patients with isolated EA. Discussion: We found significant improvements both in terms of analgesia and in functional parameters adding a FNB to continuous EA following TKA. Combination of the two techniques has a sound basis for preventing severe post-operative pain after TKA

Background:. Total knee replacement (TKR) is a frequent and effective surgery for knee osteoarthritis. Postoperative pain is under concern and can be relieved by different methods, including femoral nerve block (FNB). The efficacy of FNB on pain relief was associated with the absence of clinical impact when measured with the range of motion (ROM). Recent studies suggest that the quadriceps strength is the best indicator of functional recovery after TKR. The goal of this study is to compare the quadriceps strength recovery after TKR according to the kind of analgesia (patient control analgesia (PCA) with or without FNB) Hypothesis: the FNB delays the QSR at short and mid-term follow-up. Methods:. Prospective randomized trial with single-blind assessment involving 135 patients admitted for TKR in an academic center. Randomization into one of the three following groups: A) Continuous FNB 48h + PCA B) Single-shot FNB and PCA C) PCA alone. Groups were comparable for demographic and surgical data. The FNB was realised and controlled (electric stimulation) by an expert anesthesiologist before the surgery. Follow-up standardised in all groups with blinded assessors. Quadriceps strength measured with a validated dynamometer at 6 weeks, 6 and 12 months. Secondary outcomes included clinical evaluation (ROM, pain, stability) and functional scores (SF-36 v2, WOMAC). Multivariate analysis (Kruskal-Wallis, Mann-Whitney) for main outcomes and Spearman factor for correlation. Sample size calculated for alpha 5% and study power 80%. Results:. 111 patients available for 6 weeks follow-up (A-B-C:40-38-33) and 104 (36-36-32) at 6 and 12 months. Two patients in group B excluded for direct fall in the first postoperative week with extensor mechanism rupture and peri-prosthetic femoral fracture. QSR is significantly decreased in patients with FNB at all times (mean, 95% IC): 6 weeks (A 51.3%, 44.1–58.5; B 62.2%, 55.2–69.2; C 77.4%, 70.7–84.1; p < 0,05), 6 months (A 65.4%, 57.9–72.9; B 82.1%, 74.2–90; C 95.7%, 88.5–102.9; p < 0,05) and 12 months (A 87.8%, 82.1–93.5; B 97.8%, 89–106.6; C 104.8%, 96.1–113.5; p < 0,05). No significant difference between continuous or single-shot FNB. Higher ROM in group C at all times (p 6 weeks = 0,046; p 6 months = 0,159; p 12 months = 0,026). No correlation between ROM and QSR (rho = 0,07; p = 0,23). Better functional results in the group C at all times (p < 0,05), with good correlation to QSR (rho = 0,177; p = 0,032). Slight difference in analgesic effect of FNB (p = 0,14). Conclusion:. Femoral nerve block has a negative influence on QSR at short and mid-term follow-up and delays the rehabilitation after TKR. QSR is actually the most sensitive indicator of functional recovery after TKR and is better related to functional tests than ROM. This can explain the harmlessness of FNB in previous studies. FNB should not yet be recommended for analgesia after TKR

Our study is still in progress. The results mentioned in the abstract are preliminary results. The final results will be provided at the time of presentation. Over the past decade, the widespread availability of high-resolution ultrasonography coupled with advances in regional anaesthesia have popularised peripheral nerve blocks for anterior cruciate ligament reconstructions (ACLRs). The aim of this study is to investigate whether the femoral nerve block (FNB) administered at the time of ACLR has any long-term impact on the quadriceps strength as compared to patients who did not receive a FNB. This is a retrospective study. Four hundred charts of patients who underwent ACLR at our institution and had subsequent Biodex testing (an isokinetic rehabilitation test that provides objective information about muscle strength deficits and imbalances of the operated leg compared to the non-operated leg) from 2004 to 2015 were reviewed. Patients who had prior ipsilateral knee surgery, multi-ligament knee injury or at extreme ages were excluded from the study. The following baseline patient characteristics was recorded for each reviewed chart: age, sex, medical comorbidities, the date of the injury, date of the surgery, surgery technical notes and associated procedures, the surgeon, the hospital were the patient was operated, the Biodex test date and the Biodex test results. Data extraction assessed any association between the ACLR patients' who received FNB with the results of the Biodex test after completing the rehabilitation protocol. Descriptive statistics were used to compare the type of anaesthesia, mode of pain control and the results of the Biodex tests between patients grouped by the mode of anaesthesia used at the time of surgery (FNB versus no FNB). A multivariate regression model then compared quadriceps strength (inferred by Biodex test results) between groups while controlling for baseline differences between groups. Fifty five percent of the ACLR patients received FNB compared to 45% that did not receive FNB over the last 11 years of performing ACLRs (2004–2015) at our institute. Fifty percent of the patients that received FNB failed to achieve more than or equal to 80% quadriceps strength (compared to the contralateral non-operated leg) at 6 months on Biodex test. On the other hand, only 20% of the non-FNB group failed to achieve more than or equal to 80% quadriceps strength. This study lead us to think that ACLR patients that received FNB are significantly weaker in quadriceps strength at 6 months post ACLR in comparison to non-FNB ACLR patients. This finding subsequently might affect the time needed to return to sports and might indicate a considerable clinical consequence of the FNB on ACL-reconstruction patients

Background. Total knee arthroplasty is associated with early postoperative pain. Appropriate pain management is important to facilitate postoperative rehabilitation and positive functional outcomes. This study compares outcomes in TKA with three techniques; local infiltration analgesia, single shot femoral nerve block and intrathecal morphine. Methods. Forty-five patients undergoing elective primary Total Knee Arthroplasty (TKA) with were randomized into one of three groups in a double blind proof of concept study. Study arm 1 received local infiltration analgesia ropivacaine intra-operatively, an elastomeric device of ropivacaine for 24 hours post-op. Study arm 2 received a femoral nerve block of ropivacaine with placebo local infiltration analgesia and placebo intrathecal morphine. Study arm 3 received intrathecal morphine, placebo femoral nerve block and placebo local infiltration analgesia. All patients received standardized pre-operative, intraoperative and Post-operative analgesic medication. Participants were mobilized at 4 hrs, 24hrs and 48 hrs post operation. Range of Motion, Visual Analogue Scale (VAS) pain intensity scores and two minute walk test and Timed Up and Go test were performed. Postoperative use of analgesic drugs was recorded. Knee Society Score (KSS), Oxford Knee Score and Knee Injury and Osteoarthritis Outcome Score (KOOS) were completed at preoperative and 6 weeks post op. Results. Assessment of the efficacy of analgesia will be conducted using VAS pain scores collected preoperatively, 0–24hrs and 24–48 hours postoperatively between the three randomized groups. Frequency of use of other analgesia and need for PCA will be compared between groups at 0–24hr and 24–48hrs post operatively. The assessment of functional outcomes will be measured between the three groups by comparing the ability to mobilize the first 4 hrs after surgery, maximal flexion and extension, two minute walk test and timed up-and-go preoperatively, on postoperative day 1 and 2 and 6 weeks. Patient reported outcome measures KSS, Oxford Knee score and KOOS will be compared for the three study arms. Conclusion. Results from the study will provide important information for the management of TKA in the hospital setting. The comparison of the three commonly used analgesic techniques and mobilization outcomes are pertinent for physiotherapy and rehabilitation management, anaesthetic specialists, nursing staff, orthopaedic surgeons and patients

Total knee arthroplasty is associated with early postoperative pain. Appropriate pain management is important to facilitate postoperative rehabilitation and positive functional outcomes. This study compares outcomes in TKA with three techniques; local infiltration analgesia, single shot femoral nerve block and intrathecal morphine. Methods. Forty-five patients undergoing elective primary Total Knee Arthroplasty (TKA) with were randomized into one of three groups in a double blind proof of concept study. Study arm 1 received local infiltration analgesia ropivacaine intra-operatively, an elastomeric device of ropivacaine for 24 hours post-op. Study arm 2 received a femoral nerve block of ropivacaine with placebo local infiltration analgesia and placebo intrathecal morphine. Study arm 3 received intrathecal morphine, placebo femoral nerve block and placebo local infiltration analgesia. All patients received standardized pre-operative, intraoperative and Post-operative analgesic medication. Participants were mobilized at 4 hrs, 24hrs and 48 hrs post operation. Range of Motion, Visual Analogue Scale (VAS) pain intensity scores and two minute walk test and Timed Up and Go test were performed. Postoperative use of analgesic drugs was recorded. Knee Society Score (KSS), Oxford Knee Score and Knee Injury and Osteoarthritis Outcome Score (KOOS) were completed at preoperative and 6 weeks post op. Results. Preliminary results of 32 participants convey the positive outcomes after total knee replacement demonstrated by the improvement in Oxford Knee Score and Knee Osteoarthritis Outcome score. There are marked improvements in the 2-minute walk tests at the six week time-point. At day one post-operative only 5 participants were unable to walk. Patient-controlled analgesia was used on 5 occasions on day one, 2 of which continued on day two. Sedation scores were recorded in six participants on day one and 2 on day two. Nausea was reported in 5 cases on day one and 9 on day two. Urinary catheter was needed in 5 cases on day one. Importantly the study remains blinded, therefore an analysis of the three study arms is not available and is therefore currently difficult to report on the statistical significance. There will be further assessment of the efficacy of analgesia using VAS pain scores, analgesia consumption and side effects collected preoperatively, 0–24hrs and 24–48 hours postoperatively between the three randomized groups. The assessment of functional outcomes will be measured between the three groups by comparing the ability to mobilize the first 4 hrs after surgery, maximal flexion and extension, two minute walk test and timed up-and-go preoperatively, on postoperative day 1 and 2 and 6 weeks. Conclusion. Results from the study will provide important information for the management of TKA in the hospital setting. We anticipate completion of all 45 surgeries in the next 2 months. The Blinding codes with be broken thereafter and full data analysis performed. The comparison of the three commonly used analgesic techniques and mobilization outcomes will allow enhanced management of patient's post-operative pain with earlier discharge from hospital an lower complication rates

Purpose. To evaluate the effectiveness of post-operative pain management using the intra-operative peri-articular injection(PAI) and/or electromyography (EMG)-guided preoperative femoral nerve block (FNB) in total knee arthroplasty(TKA). Materials and Methods. From March 2013 to February 2014, 90 knees which underwent primary TKA by one surgeon were included in our study. The patients were classified into three groups; a single injection FNB with an EMG guide (Group I, 30 knees), intra-operative PAI (Group II, 30 knees) and both FNB and PAI (Group III, 30 knees). Pain at rest and moving was evaluated by Visual Analogue Scale (VAS) at postoperative 0, 4, 8, 24 and 48 hours. Postoperative range of motion, time to walking, total blood loss, amount of opioid consumption and complications were compared in each group. Results. VAS immediately after surgery was 67.9 in group I, 54.6 in group II and 54.7 in group III. VAS was significantly higher in group I than group II and III (p=0.005), but was not significantly different between group II and III (p>0.05). VAS at postoperative 4 and 8hr showed similar results. VAS at postoperative 24 hr was 49.6 in group I, 56.4 in group II and 46.7 in group III, which was significantly higher in group II than group I and III (p=0.043). After postoperative 48hr, there were no differences in group I, II and III. The total amount of opioid consumption in group III was smaller than that in group I and II (p=0.017). There were no differences in postoperative range of motion, time to walking and total blood loss. There was one case with temporary peroneal nerve palsy in group II and no infection in all cases. Conclusion. PAI was more effective than FNB for early (0∼8hr) postoperative period after TKA. However, PAI showed rebound pain at 24hr after TKA. PAI in combination with FNB could enhance the effect of postoperative pain management from immediate postoperative period to 24hr

Purpose: Continuous femoral nerve block (CFNB) has been revealed to be a safe and effective method to decrease postoperative pain after total knee arthroplasty (TKA). However, optimal duration for CFNB to decrease pain and accelerate rehabilitation program after TKA has not been addressed. We, therefore, compared three groups of patients which had different duration of CFNB (0, 2, and 5days) in this study. Methods: Sixty patients who received primary TKA for osteoarthritis were divided into three groups based on the duration to receive CFNB for 0day, 2days or 5days (twenty patients for each group). Ropivacaine 2mg/mL was given through the femoral nerve catheter using elastomeric infusers (delivering 2ml/hr for each group). Outcomes including visual analog scale (VAS) pain scores and range of motion (ROM) were compared at 1st, 3rd, 6th, 14th and 21th days after surgery. In addition, the postoperative date when patients could walk stably with parallel bar, walker, or T-cane were recorded and compared. Results: At 1st and 3rd day postoperatively, the VAS was significantly better in the CFNB 2 days and CFNB 5 days group than in the CFNB 0 day group (P< 0.05). ROM did not show significant difference among the three groups over postoperative days 1st to 21st (P> 0.05), although groups with the CFNB showed greater ROM at all time points. The CFNB 5 days group obtained stable walking ability with T-cane earlier than other groups (P< 0.05). No patient had any side effect by having CFNB in this study. Discussion: Postoperative use of CFNB reduced pain at first 3days, and shorten the time to acquire stable walking ability after TKA. We conclude that CFNB should be kept for 5days after surgery to decrease pain and accelerate rehabilitation program after TKA

The purpose of this double-blinded prospective study was to evaluate the effectiveness of electromyography (EMG)-guided preoperative femoral nerve block (FNB) for postoperative analgesia in total knee arthroplasty (TKA). Forty knees of primary TKA by one surgeon were included in our study. One doctor performed a single injection FNB with an EMG guide in EMG group (23 knees) and with a blind maneuver in control group (17 knees). The same 10ml of 0.375% ropivacaine was injected in both groups. Same postoperative rehabilitation protocol was applied to all patients. Continuous passive motion was started at postoperative 1st day and weight bearing was started as soon as possible. Intravenous patient-controlled analgesics which contained 30mg of morphine were used until postoperative 72 hours and no additional intravenous, intramuscular or oral analgesics were used. Pain was evaluated by Visual Analogue Scale (VAS) and Postoperative Pain Score (PPS) at postoperative 4, 24, 48 and 72 hours. The amount of opioid consumption and complication were compared between two groups. VAS score was 6.8 in EMG group and 8.0 in control group at postoperative 4 hours, 6.2 and 7.1 at postoperative 24 hours, 5.3 and 5.9 at postoperative 48 hours, and 4.6 and 5.7 at postoperative 72 hours, respectively. PPS was 2.2 in EMG group and 2.2 in control group at postoperative 4 hours, 2.1 and 2.1 at postoperative 24 hours, 1.6 and 1.7 at postoperative 48 hours, and 1.4 and 1.6 at postoperative 72 hours, respectively. The amount of opioid consumption was 6.0mg in EMG group and 7.2mg in control group during postoperative 24 hours, 2.7mg and 3.2mg during postoperative 24–48 hours, and 1.7mg and 3.2mg during postoperative 48–72 hours, respectively. There was no complication in either group. Pain tended to decrease more in EMG group than control group, especially VAS at postoperative 4, 24 and 72 hours (p< 0.05). The demand of opioid was significantly smaller in EMG group during postoperative 24 hours and 48–72 hours (p< 0.05). EMG-guided single FNB before TKA allowed better postoperative pain relief and reduced the demand of pain killer

A prospective randomised study was carried out to compare two methods of pain control following arthroscopically assisted ACL reconstruction. Twenty patients each were randomly recruited to receive either femoral nerve block with 0.5% Bupivicaine or an intra-articular injection with the same. Both groups were prescribed Diclofenac regularly and Coproxamol as required. Visual analogue scores (VAS) were used to assess pain levels preoperatively, four hours postoperatively and on the morning after. The duration between surgery and the first dose of PRN analgesia was recorded, along with the total quantity of analgesia required before discharge. Patients with associated PCL or collateral ligament injuries were excluded beforehand. Both groups were evenly matched for age (t-test p< 0.05). Tourniquet time did not differ significantly between the groups (t-test p:0.24). The VAS pain levels were not significantly different at four hours and the first morning postoperatively in both groups. Femoral block (Ave VAS: 21 & 25) did not confer a significant advantage (t-test p: 0.69, 0.7) over intra-articular injections of Bupivicaine (Ave VAS: 25 & 22). The total quantity of Coproxamol consumed did not vary significantly (p=0.99). There was no correlation between tourniquet time and postoperative pain (r=0.19, 0.08). All but one patient was discharged home on the first postoperative morning. Our study demonstrates that pain levels can be sufficiently controlled by intra-articular infiltration of Bupivicaine coupled with oral analgesia. The level of pain relief achieved could allow this procedure to be increasingly performed in a day surgery setting without the need for femoral block thereby allowing for quicker mobilisation

Purpose: Unicompartmental replacement for medial compartment arthrosis of the knee has become popular with eligible patients because of the shortened recovery time, decreased tissue damage and easier future revision. Contemporary multimodal anesthesia has added the potential to safely perform this as outpatient surgery reducing inpatient bed burden. We describe our initial pilot experience with this approach.

Method: The first 25 patients who fulfilled the criteria developed underwent same day surgery for unicompart-mental arthroplasty for medial (19) or lateral (3) compartment replacement with either the Oxford knee (20) or the Uniglide (2). All patients were treated with an indwelling femoral nerve catheter supplied by Ropivacaine through a constant release pump (Stryker) which was discontinued at 48 hours. Home care support was made available in first 72 hours by way of RN and physiotherapy visits and mandatory use of walker or crutches for the first 48 hours.

Results: Patients in this cohort were universally very satisfied with the model of postop care as described and particularly pleased to avoid a hospital stay. Eighty percent of those who were offered this model chose it. The use of narcotic oral medication was consistently about 50% less than that observed to similar inpatients treated without catheter, and eight patients had complete opioid sparing experience. There were no complications related to the catheter, in particular serious falls or longer term neurologic sequelae. The clinical results were very good and equal to those who were in patients.

Conclusion: Outpatient unicompartmental replacement can be performed safely recognizing the decreased surgical trauma and pain stimuli associated with UKR and a relatively younger and healthier cohort screened for this alternative. These patients are amongst the most satisfied with their perioperative course and all would do the same again if given the chance. Other models of analgesia could be considered, though the catheter does seem to have a large opioid sparing effect that likely contributed to patient well being and satisfaction.

Introduction: Regional anaesthesia is used recently more often in minor and intermediate orthopaedic procedures. This study evaluates regional anaesthesia in knee arthroscopy.

Patients and Method: From September 2002 to February 2003, sixty three patients had knee arthroscopy by regional blockade, (mean age 28, 3 years). Thirty ml Ropivacaine 5% and 10 ml Lidocaine 2% were used to block sciatic and femoral nerve with nerve stimulator help.

Results: They were realized 31 meniscectomies, 8 meniscal repairs, 6 primary ACL reconstructions, 2 ACL revisions, 5 chondroplasties, 6 lateral releases, 2 Fulkerson osteotomies, 4 plica removals, 2 adhesionlysis, 2 localized villonodular synovitis, one total synovectomy and one arthroscopic removal prepatellar bursa. There was no complication concerning the nerve blockade. Two of 8 ACL patients required general anesthesia and one had sedation during the procedure. Sedation also was necessary in three patients with lateral release and two meniscal repairs. The remaining 55 patients were tolerated the arthroscopic procedure without any additional help. All patients hospitalized less than 24 hours except patients with ACL reconstruction. They needed 1, 2 analgesic pills per person. The cost for the anesthetic procedure was 40 euros.

Conclusion: Regional anesthesia has the advantage of avoiding the complications of general anesthesia, is of low cost and well bearable from the majority of patients. It offers prolonged postoperative analgesia and has no complications.

Objectives. Effective analgesia after total knee arthroplasty (TKA) improves patient satisfaction, mobility and expedites discharge. This study assessed whether continuous femoral nerve infusion (CFNI) was superior to a single-shot femoral nerve block in primary TKA surgery completed under subarachnoid blockade including morphine. Methods. We performed an adequately powered, prospective, randomised, placebo-controlled trial comparing CFNI of 0.125% bupivacaine versus normal saline following a single-shot femoral nerve block and subarachnoid anaesthesia with intrathecal morphine for primary TKA. Patients were randomised to either treatment (CFNI 0 ml to 10 ml/h 0.125% bupivacaine) or placebo (CFNI 0 ml to 10 ml/h normal saline). Both groups received a single-shot femoral nerve block (0.25% 20 ml bupivacaine) prior to placement of femoral nerve catheter and subarachnoid anaesthesia with intrathecal morphine. All patients had a standardised analgesic protocol. The primary end point was post-operative visual analogue scale (VAS) pain score over 72 hours post-surgery. Secondary outcomes were morphine equivalent dose, range of movement, side effects, and length of stay. Results. A total of 86 patients were recruited. Treatment and placebo groups were comparable. No significant difference was found in VAS pain scores, total morphine equivalent requirements, side effects, range of movement, motor block, or length of hospital stay. Conclusion. No significant advantage was found for CFNI over a single-shot femoral block and subarachnoid anaesthesia after TKA. Cite this article: Bone Joint Res 2015;4:11–16

Regional anaesthesia is integral to best practice analgesia for patients with neck of femur fractures (NOFFs). These patients are generally frail and are vulnerable to side effects of opioid analgesia. Femoral nerve block (FNB) or fascia-iliaca block (FIB) can reduce opioid requirement. Literature supports good efficacy for extra-capsular NOFFs however it is acknowledged to be suboptimal for intracapsular fractures. We present a novel technique, using point of care ultrasound guidance to perform hip ultrasound guided haematoma (HUSH) aspiration, and injection of local anaesthetic (block) for intracapsular NOFFs. This a case control series. A consecutive series of cognitively intact patients, with an isolated intra-capsular NOFF, received a HUSH block using 10mls of 0.75% Ropivicaine. Haematoma was aspirated and volume recorded. This was performed in addition to standard NOFF pathway analgesia that includes a FIB and multimodal analgesia including opioids. Visual Analogue Scale (VAS)pain scores at rest and on movement were recorded pre and post procedure as well as combined morphine equivalent units administered post HUSH block. The control arm was a retrospective group of similar patients who followed the routine care pathway including a FIB. VAS pain scores from observation charts and usage of morphine equivalent units were calculated. Ten patients consented to receive HUSH blocks and we included thirty-eight patients in our control series. The HUSH block group showed mean VAS pain score of 4.2/10 at rest and 8.6 on movement prior to block. In the time after the block, VAS pain scores reduced to 1.5 at rest (p=0.007) and 3.1 on movement (p=0.0001) with a mean total morphine equivalent use of 8.75mg. This is significantly different from the control group's mean VAS pain at rest score 6.9 (p=0.0001) and 24.1mg total morphine equivalent (p=0.07). HUSH Block in addition to fascia iliaca block appears to significantly better pain relief in intracapsular neck of femur fracture patients when compared to fascia iliaca block alone. We believe it is relatively easy to perform with readily available ultrasound scanners in emergency departments

Background and objectives: Total knee replacement (TKR) produces severe postoperative pain. Peripheral nerve blocks can be used as analgesic adjuncts after TKR. The use of peripheral nerve block has certainly reduced the use of opiates by 50%; however adding the sciatic nerve block to the femoral nerve block is controversial. The aim of this study was to compare femoral and femoral plus sciatic nerve blocks in postoperative pain management of patients undergoing TKR. Materials and Methods: Total of 42 patients were studied. Twenty patients with an average of 75yrs (51–86yrs) received femoral nerve block alone. Twenty-two patients with an average age of 69yrs (53–83yrs) received femoral plus sciatic nerve block. 0.5% Chirocaine was used for nerve blocks. There was no significant difference between two groups in terms of pre-operative pain, pre-operative deformity, ROM and patella replaced. The primary outcome measures used were visual analogue scale (VAS) pain scores at 24 hours, 48 hours and 72 hours after the surgery. The amount of opiate consumption and PCA (patient controlled analgesia) used were also recorded. The secondary outcomes were postoperative nausea and vomiting, straight leg raise, neurological deficit, knee flexion, independent mobility and discharge from the hospital. Results: The results showed significant decrease in the amount of pain in the femoral nerve block group than the combined nerve block patients. Patients who had combined nerve block complained of heaviness in the legs and were slow to mobilise. There was no significant difference in consumption of opiates, use of PCA, nausea and vomiting, independent mobility and the time of discharge from the hospital between the two groups. Conclusion: The addition of sciatic nerve block to the femoral nerve block does not provide any additional benefits in TKR