Background data. The clinical outcome of decompression and posterolateral spinal fusion for patients with degenerative lumbar spinal stenosis may be influenced by a variety of pathophysiologic factors. Among them, sagittal balance of the spine has gained new interest regarding its correlation with low back pain following lumbar spine surgery. Objectives. To study the effect of sagittal spinal alignment on low back pain in patients operated for degenerative lumbar spinal stenosis. Study design. Multifactorial analysis. Materials and Methods. In this prospective randomized comparative study 45 consecutive patients were included, who underwent decompression for symptomatic degenerative lumbar spinal stenosis and two-, three- or four levels posterior transpedicular fixation with three instrumentations of different stiffness (dynamic, semirigid and rigid) plus posterolateral fusion. All patients were followed up for an average period of four-year radiologically and with SF-36 (domain Bodily pain) to investigate possible correlations between anthropometric parameters, stiffness and extension of instrumentation, roentgenographic sagittal balance, motion in adjacent free level and low back pain. Results. Bodily pain scores improved with the time lapsed from index operation (P< 0.0001). As the distance of the apical lumbar vertebra from plumbline increased, bodily pain score improved significantly (P=0.0006). At the last observation following surgery patients had better Bodily pain score than that they had preoperatively (P=0.0001) and six months postoperatively (P< 0.0001) respectively. Patients, who received four levels instrumentation had higher Bodily pain score (P=0.0245) than their counterparts who received two levels instrumentation. Discussion. Maintenance or even improvement of lumbar lordosis, instrumentation of three and four vertebrae, and time lapsed from index operation was associated with improvement of back pain. On contrary, patients’ age, gender, instrumentation stiffness, vertebral inclination, thoracic kyphosis and sagittal lumbar flexibility did not affect the surgical outcome regarding back pain in adult patients who underwent decompression and stabilization 2 to 4 levels for degenerative lumbar spinal stenosis

Degenerative lumbar spinal stenosis is one of the most frequent surgical indications of spinal surgery in the elderly patient group. Because of the progression of the disease and neurologic deficiencies, patients’ quality of life is affected. We aimed to evaluate the postoperative quality of life of the surgically treated spinal stenotic patients. Between 1998 and 2009, 38 patients, who were surgically decompressed and enstrumentated in our clinic were included to the study. The patients were preoperatively and postoperatively evaluated with Visual Analogue (Scale (VAS) and Japanese Orthopaedics Association (JOA) criterias. The same patient group were re-evaluated on the postoperative 6th month with Hamilton anxiety and depression scale, on the 12th month with short form-36 and Oswestry pain scoring scales to measure the quality of life. Mean age of 38 patients (31 female, 7 male) was 59.6 (range 44 to 82). Mean preoperative VAS was 7.97 and postoperative VAS was 2.28. The pain decreased 56.9%. According to JOA criterias, in 3 patients (7.89%) no recovery, in 13 patients (34.2%) less than 50% recovery and in 22 patients (57.8%) more than 50% recovery was obtained. On the 6th month, according to Hamilton anxiety and depression scale, in 12 patients anxiety and in 3 of these patients depression which needs treatment was observed. The pain of all the patients with anxiety recovered meaningfully (42.3%) but according to JOA, less than 50% recovery could be obtained. Surgically treated spinal stenosis patients improved clinically and radiologically and this affected the patients’ quality of life positively

Surgical decompression is the recommended treatment for patients with moderate to severe degenerative lumbar spinal stenosis (DLSS). Although complication risk has been shown to be higher with concomitant fusion, the success rate is not necessarily superior. This study analyzed the success rates of 58 DLSS patients treated with decompressive surgery. Twenty patients received concomitant instrumented fusion. Outcomes were measured with the Swiss Spinal Stenosis Questionnaire (SSSQ) completed pre-operatively and at least 12 months post-operatively (range 12 to 54 months). Overall, 63.8% of the patients had significant clinical improvement in Symptom Severity, 55.2% had significant clinical improvement in Physical Function, and 58.6% of the patients were at least somewhat satisfied; 43.1% (25/58) of the patients met all three criteria and were considered to be clinically successful. There were no statistically significant differences between the clinical success rates of the non-fusion and fusion groups, but the change in mean change of the Symptom Severity score for the fusion group was significantly greater than that of the non-fusion group. Also, patients with more severe pre-operative symptoms and more physical function restrictions had better success results than those patients with more mild symptoms and less restrictive physical function. The results of this study demonstrate that decompressive surgery with concomitant fusion does not impose a greater risk than decompressive surgery alone and the clinical results of the added fusion are somewhat superior to decompressive surgery alone

The aim of the study was to assess the effectiveness of surgical treatment for degenerative lumbar spinal stenosis (LSS) as compared with non-operative measures. Four university hospitals contributed, after agreement on study protocol, surgical rationale and non-operative procedures (For details, see . Spine. 2007. ;. 32. :. 1. –8. ). Ninety-four patients were randomized into a surgical or nonoperative treatment group, 50 and 44 patients, respectively. Surgery comprised undercutting laminectomy of the stenotic segments, in 10 patients augmented with transpedicular instrumented fusion. The primary outcome was based on assessment of functional disability using the Oswestry Disability Index (ODI, scale 0–100). Intensity of leg and back pain (scales 0–10), as well as self-reported walking ability, were recorded at randomization and at follow-ups at 6, 12, 24 months and on average 6 years after the randomization. At the 2-year follow-up, back and leg pain scales and ODI had improved more in the surgical than the nonoperative group (p-values for global difference < 0,01). At the 6-year follow-up the mean difference in ODI in favor of surgery was 9.5 (95% confidence interval 0.9–18.1). However, the intensity of pains did not any-more differ between the two treatment groups at the 6-year follow-up. Walking ability did not differ between the treatment groups at any time point. Of the 44 patients in the nonoperative group, 4 had been subjected to surgery within two years after randomization because of persistent symptoms. We conclude that surgical treatment improves functional ability in lumbar spinal stenosis. We emphasize that improvement also occurs after nonoperative measures. We recommend starting treatment with non-operative measures during a 2-year surveillance period, as during this period only 10 per cent of the patients will need surgical intervention

Aims

We compared decompression alone to decompression with fusion surgery for lumbar spinal stenosis, with or without degenerative spondylolisthesis (DS). The aim was to evaluate if five-year outcomes differed between the groups. The two-year results from the same trial revealed no differences.

Aims

The aims of this study were first, to determine if adding fusion to a decompression of the lumbar spine for spinal stenosis decreases the rate of radiological restenosis and/or proximal adjacent level stenosis two years after surgery, and second, to evaluate the change in vertebral slip two years after surgery with and without fusion.

Introduction and Aims: To evaluate the long-term results of an operation which does not involve instrumentation or fusion and which leaves the midline structures intact. Method: A retrospective clinical and radiological review of consecutive patients. Results: One hundred and sixty patients (87 females and 73 males) with a mean age at operation of 68 (range 40–90); the majority of patients (79%) had either a one or two level bilateral decompression. The most common level decompressed was the L4/5 level (91%). The mean post-operative follow-up was 22 months. Summary of background data: spondylosis, commonly involving a degenerative listhesis, is the most common cause of stenosis in the lumbar spine. The symptoms arise from root compromise of the stenotic level and surgery offers the only permanent cure. To date, the standard procedure remains a laminectomy with fixation and fusion in the presence of possible instability. A laminectomy, however, destabilises the spine and the instrumented fusion makes it a much bigger operation in patients often not best placed to cope with it. There has been, therefore, a need for an effective operation that does not compromise spinal stability. Conclusion: At six weeks post-operation, 141 patients (85%) reported relief of leg pain and this rose to 90% at six months. One hundred and fifty-three patients (96%) reported an increase in their walking distance. Of those patients who also presented with back pain pre-operatively, 79% reported an improvement. There were no significant post-operative complications. The results were sustained at follow-up. The operation of limited segmental decompression for degenerative lumbar spinal stenosis has been found to be effective, safe, and providing good long-term results, without compromising the existing spinal stability. Appropriate patient selection and attention to operative technique are of paramount importance

Objective: To evaluate the long term results of an operation developed to decompress the roots at the stenotic level, preserve the midline structures, and not use instrumentation or fusion. Design: A retrospective clinical and radiological review of consecutive patients operated on for spinal stenosis secondary to lumbar spondylosis. Subjects: One hundred and sixty patients (eighty seven female and seventy three male) with a mean age at operation of sixty eight (range 40–90). Sixty one patients (38%) had a degenerative listhesis causing stenosis. The mean post operative follow-up was twenty two months (range two months to fourteen years). Summary of background data: Lumbar spondylosis, commonly involving degenerative listhesis, is the commonest cause for spinal stenosis in the lumbar spine. Surgery offers the only permanent cure. The standard procedure remains a laminectomy with fixation and fusion in the presence of possible instability. The laminectomy destabilises the spine and the instrumented fusion makes it a much bigger operation in patients often not best placed to cope with it. There is a need, therefore, for an effective operation that does not compromise spinal stability. Results: At six weeks one hundred and forty one patient (85%) reported relief of leg pain and a further nine patients were improved at three to six months. 52% of the patients reported a concomitant improvement in back pain. The results were sustained at follow-up. The operation was not responsible for the development of a new spondylolisthesis. A minimal increase in an existing degenerative listhesis was seen in two patients only without compromise of their good results. There was no revision surgery at any of the operated levels. Conclusions: The operation of segmental spinal decompression for degenerative lumbar spinal stenosis has been found to be effective, safe, and give good long term results, without compromising the existing spinal stability. Patient selection and attention to operative technique are essential

Introduction: Thickened ligamentum flavum (LF) is a major contributor to the clinical syndrome of lumbar canal stenosis (LCS). The patho-mechanisms responsible for this phenomenon remain unclear. Cysts adjacent to facet joints (FJ) in the spine are regarded as rare entities that may uncommonly contribute to LCS. Inaccurate pathological interpretation and unawareness of a key anatomical feature has generated erratic terminology and confusion about their origin. Methods: Twenty-seven consecutive patients with radiologically confirmed central canal or lateral recess stenosis underwent lumbar laminectomy for neurogenic symptoms. Surgical specimens comprising en bloc excision of LF and medial inferior facet (to retain LF and FJ relationships) were examined microscopically following staining with haematoxylin-eosin and Miller’s elastic stain. Controls were facet/LF specimens from 89 cadaver lumbar spines. Results: Mean LF thickness was 8.9 mm (+/− 0.3 mm SEM) at the operated levels and 2.9 mm (+/− 0.3 mm) at the non-operated, adjacent levels (p < 0.01). Twenty-eight synovial cysts (8 bilateral, 12 unilateral) were present at a single level in 20 (74%) patients. Synovial cysts per spine level were: L1/2 = 0; L2/3 = 3; L3/4 = 7; L4/5 = 16; L5/S1 = 2. The cyst levels all showed advanced osteoarthritis and LF degeneration. Ten patients (50 %) with cysts had pre-existing degenerative spondylolisthesis (DS). Only 5 patients had pre-operative radiological apperances of unilateral facet cysts. Therefore 82 % of our observed synovial cysts were microscopic or occult. The synovial cysts communicated with the FJ via a bursa-like cleft within the LF, and their linings of synoviocytes and other cells contained fragments shed from the articular surface. The control cadaver specimens revealed that a synovial bursa or intra-ligamentous out-pouching from the synovial cavity was present in 90% of normal LF at L4/5 and was up to 12 mm in length. This intra-ligamentous synovial recess, either wholly or partially lined by synoviocytes, was only present in 55% of specimens at L1/2 with a maximum length of 5 mm. Several other juxtafacet cyst types were observed in the experimental group and a novel classification based upon pathological findings is presented. Discussion: Para-facetal intraspinal cysts are common in degenerative lumbar spinal stenosis. DS is also a frequent finding but is statistically unrelated to cyst formation (Chi-square: p=0.187). We have found that debris from osteoarthritic facet joints enters a bursa-like cleft within the LF where it becomes incorporated into the wall where it excites a granulomatous reaction leading to blockage and synovial cyst formation. The existence of this channel has not been reported previously. We suggest that microscopic synovial cysts contribute significantly to the ligamentous thickening seen in LCS. We also present a novel classification of juxtafacet cysts based on our pathological findings