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Bone & Joint Research
Vol. 12, Issue 9 | Pages 559 - 570
14 Sep 2023
Diagnosis of periprosthetic joint infections in patients who have rheumatoid arthritis
Wang Y Li G Ji B Xu B Zhang X Maimaitiyiming A Cao L
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Aims

To investigate the optimal thresholds and diagnostic efficacy of commonly used serological and synovial fluid detection indexes for diagnosing periprosthetic joint infection (PJI) in patients who have rheumatoid arthritis (RA).

Methods

The data from 348 patients who had RA or osteoarthritis (OA) and had previously undergone a total knee (TKA) and/or a total hip arthroplasty (THA) (including RA-PJI: 60 cases, RA-non-PJI: 80 cases; OA-PJI: 104 cases, OA-non-PJI: 104 cases) were retrospectively analyzed. A receiver operating characteristic curve was used to determine the optimal thresholds of the CRP, ESR, synovial fluid white blood cell count (WBC), and polymorphonuclear neutrophil percentage (PMN%) for diagnosing RA-PJI and OA-PJI. The diagnostic efficacy was evaluated by comparing the area under the curve (AUC) of each index and applying the results of the combined index diagnostic test.

Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_III | Pages 348 - 348
1 Sep 2005
X-RAY CHANGES ASSOCIATED WITH DISCOID LATERAL MENISCI
Hunt D Ji B
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Introduction and Aims: A number of x-ray appearances have been identified as indicative of discoid menisci. None are reliable or statistically significant. The purpose of this paper is to identify a reliable radiographic sign, diagnostic of the discoid lateral meniscus.

Method: The anteroposterior view radiographs of 14 knees in 13 patients with arthroscopically proven discoid meniscus were studied. Ages ranged from 11 to 26, with a mean age of 18.4 ± 4.84 years, right to left ratio 9/5, male to female ratio 8/5. Fifteen normal knees in 14 people were used as a control group, age from 11 to 30, mean age 16.20 ± 6.41, right to left ratio 8/7, male to female ratio 6/8. The parameters measured were: Lateral Joint Space (LJS); Height of the Lateral Tibial Spine (LTS); change of the Medial Tibial Spine (MTS); Height of Fibular Head (HFH); changes of the Edge of the Lateral Tibial Plateau (ELTP), cupping of the lateral tibial plateau, and squaring of the lateral femoral condyle.

Results: There was no significant difference between the two groups in LJS, height of LTS, cupping of the lateral tibial plateau, and squaring off of the lateral femoral condyle. There was a difference between the two groups in HFH which was statistically significant at an absolute value of p = 0.033, but not significant in normalised value p = 0.056. The medial tibial spine was sharpened in three patients.

There were 12 positive changes on ELTP out of 14 patients (85.71%) in the discoid group, while only one positive of 15 (6.67%) in the normal group, and the difference between the two groups was statistically significant at p< 0.01. The diagnosis parameters were Sensitivity (Se) = 85.71%, Specificity (Sp) = 93.33%, Positive predictive value (PV+) = 92.31%, Negative predictive value (PV−) = 87.50%, Correct rate (ñ) = 89.66%. The typical change on the edge of lateral tibial plateau is sharpening and/or formation of a spur.

Conclusion: Sharpening with spur formation on the edge of lateral tibial plateau is a diagnostic radiological sign of a discoid lateral meniscus.