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Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XLIII | Pages 67 - 67
1 Sep 2012
Morgan S Roushdi I Benerjee R Palmer S
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Introduction

Symptomatic hallux valgus is a common clinical problem, current trends is towards minimally invasive procedures. The goal of this study is to evaluate the outcome of minimally invasive chevron ostoetomy, comparing it with a matched group who had open chevron osteotomy.

Methods

Prospective study, 54 patients. MIS group 25 patients between October 2009 and November 2010. Open group 29 patients between Feb 2008 and October 2010. Inclusion criteria included, mild to moderate hallux valgus, no previous history of foot surgery, no history of inflammatory arthritis, or MTPJ arthritis. All the operations were performed by the senior author. Functional outcome and pain were evaluated using pre and post operative Manchester Oxford Foot and ankle questionnaire (MOXFQ). IMA and HVA, avascular necrosis and union were assessed. Complications and satisfaction were recorded.


Orthopaedic Proceedings
Vol. 86-B, Issue SUPP_III | Pages 351 - 351
1 Mar 2004
Tsiridis E Bhalla A Ali Z Roushdi I Goodship A Di Silvio L
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Aim: The biological activity of demineralised bone matrix (DBM) led to the discovery of bone morphogenetic proteins (BMP). OP-1 (BMP 7) is an osteoinductive protein and has been demonstrated to be capable of inducing new bone formation in rat subcutaneous tissue and in both orthotopic and heterotopic sites in primates. In this study we have investigated whether demineralisation and addition of osteogenic. protein 1 (OP-1) improves osteoinductive properties of allograft. Methods: A randomised controlled blind trial was performed in 16 rats. One group received two pellets of fresh frozen allograft; the other received two pellets of demineralised bone (DBM) intramuscularly. In each rat one pellet was treated with OP-1 (2mg/25mg of graft). The rats were sacriþced at 28 days and tissue þxed and processed for sectioning with haematoxylin and eosin for morphology and Alcian blue and Sirrus red for collagen types I, II. Qualitative observations were made and each specimen graded 0–5 on the degree of new bone formation and integration by two blind observers. Results & Conclusions: DBM with OP-1 yielded optimal results, being signiþcantly superior to allograft alone and allograft with OP-1. DBM alone was shown to be more effective compared to the allograft preparations. Hence we have shown that demineralization and OP-1 signiþcantly improve the osteoinductive properties of allograft