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Orthopaedic Proceedings
Vol. 106-B, Issue SUPP_6 | Pages 1 - 1
2 May 2024
Mayne A Saad A Botchu R Politis A Wall P McBryde C
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Radiological investigations are essential in the work-up of patients presenting with non-arthritic hip pain, to allow close review of the complex anatomy around the hip and proximal femur. The aim of this study is to quantify the radiation exposure associated with common radiological investigations performed in assessing young adult patients presenting with non-arthritic hip pain.

A retrospective review of our UK tertiary hip preservation centre institutional imaging database was performed. Data was obtained for antero-posterior, cross-table lateral and frog-lateral radiographs, along with data for the low dose CT hip protocol and the Mako CT Hip protocol. The radiation dose of each imaging technique was measured in terms of dose-area product (DAP) with units of mGycm2, and the effective doses (ED, mSv) calculated.

The mean effective radiation dose for hip radiographs was in the range 0.03 to 0.83mSv (mean DLP 126.7–156.2 mGycm2). The mean effective dose associated with the low-dose CT hip protocol was 3.04mSv (416.8 mGycm2) and for the Stryker Mako CT Hip protocol was 8.4mSv (1061 mGycm2). The radiation dose associated with use of CT imaging was significantly greater than plain radiographs (p<0.005)

Investigation of non-arthritic hip pain can lead to significant ionising radiation exposure for patients. In our institution, the routine protocol is to obtain an anteroposterior radiograph and then a specific hip sequence 3 Tesla MRI including anteversion views. This provides the necessary information in the majority of cases, with CT scanning reserved for more complex cases where we feel there is a specific indication. We would encourage the hip preservation community to carefully consider and review the use of ionising radiation investigations.


Orthopaedic Proceedings
Vol. 106-B, Issue SUPP_6 | Pages 33 - 33
2 May 2024
Dickenson E Griffin J Wall P McBryde C
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The 22 year survivorship of metal on metal hip resurfacing arthroplasty (RSA) is reported to be 94.3% with expert surgeons, in males with head sizes greater than 48mm. The 2023 National Joint Registry (NJR) report estimates survivorship of all RSA at 19 years to be 85%. This estimate includes all designs, head sizes and females. Our aim was to estimate the survivorship of RSA currently available for implantation (males only, head size >48mm, MatOrtho Adept or Smith and Nephew Birmingham Hip Resurfacing (BHR)) in those under 55 years, performed by all surgeons, compared to conventional THR.

We performed a retrospective analysis of the NJR. We included all males under 55 years who had undergone BHR or Adept RSA with head size greater than 48mm. Propensity score matching was used to produce two comparable groups of patients for RSA or conventional THR. We matched in a 3:1 ratio (THR:RSA) using sex, ASA, BMI group, age at primary procedure, surgeon volume, diagnosis and surgeon grade as covariates. The primary analysis was survivorship at 18 years. Time-to-revision was assessed using Kaplan-Meier curves. Cox's proportional hazard models were used to investigate between group differences.

4839 RSA were available for analysis. After matching the RSA and THR groups were well balanced in terms of covariates. Survivorship at 18 years was 93.7% (95% CI 89.9,96.2) in the RSA group and 93.9% (90.5,96.0) in the THR group. Despite these similar estimates the adjusted hazard ratio was 1.40 (95% CI 1.18, 1.67 p<0.001) in favour of THR.

Survivorship of the currently available RSA in males under 55 was 93.7% at 18 years, however THR survivorship was superior to RSA. These results, generalisable to UK practice, should be set against perceived benefits in functional status offered in RSA when counselling patients.


Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_10 | Pages 23 - 23
1 Aug 2021
Holleyman R Sohatee M Bankes M Andrade T McBryde C Board T Conroy J Wilson M Malviya A Khanduja V
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FAI may cause pain or functional impairment for an individual, as well as potentially resulting in arthritis and degeneration of the hip joint. Results from recent randomised control trials demonstrate the superiority of surgery over physiotherapy in patients with FAI. However, there is paucity of evidence regarding which factors influence outcomes for FAI surgery, most notably on patient reported outcomes measures (PROMs).

Our study looks to explore factors influencing the outcomes for patients undergoing surgery for FAI utilising data from the Non-Arthroplasty Hip Registry.

This study is a retrospective analysis of data collected prospectively via the NAHR database. Patients meeting the inclusion criteria, who underwent surgery between January 2011 and September 2019 were identified and included in the study. Follow-up data was captured in September 2020 to allow a minimum of 12 months follow-up.

Patients consenting to data collection received questionnaires to determine EQ-5D Index and iHOT-12 scores preoperatively and at 6 months, 1, 2- and 5-year follow-up.

Changes in outcome scores were analysed for all patients and sub-analysis was performed looking at the influence of; FAI morphological subtype, age, and sex, on outcome scores.

Our cohort included 4,963 patients who underwent arthroscopic treatment for FAI. There was significant improvement from pre-operative PROMs when compared with those at 6 and 12 months.

Pre-operatively, and at 12-month follow-up, iHOT-12 scores were significantly better for the cam / mixed groups compared to the pincer group (p<0.01).

In multivariable regression analysis, pincer pathology and a high-grade chondral lesion were associated significantly poorer iHOT-12 improvement at 6 and 12 months (p<0.05)

Age (<40 vs >40) demonstrated no statistical significance when considering 12 months outcome scores.

This study demonstrates that hip arthroscopy is an effective treatment for patients with symptomatic FAI and shows statistically significant improvements at 12 months.

The findings of this study are relevant to orthopaedic surgeons who manage young adults with hip pathology. This will help them to; predict which patients may benefit from operative intervention, and better inform patients, when undertaking shared decision making.


Orthopaedic Proceedings
Vol. 103-B, Issue SUPP_10 | Pages 33 - 33
1 Aug 2021
Holleyman R Sohatee M Bankes M Witt J Andrade T Board T McBryde C Conroy J Wilson M Khanduja V Malviya A
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Pelvic re-orientation osteotomy is a well-recognised treatment of young adults with developmental dysplasia of the hip (DDH).

The most commonly used technique is the periacetabular osteotomy (PAO), however, some surgeons favour a triple osteotomy. These techniques can also be utilised for acetabular retroversion leading to FAI.

Despite the published literature on these techniques, the authors note a scarcity of evidence looking at patient reported outcome measures (PROMs) for these procedures.

This was a retrospective analysis of prospectively collected data utilising the UK NAHR. All patients who underwent pelvic osteotomy from January 2012 to November 2019 were identified from the NAHR database. Patients who consented to data collection received EQ-5D index and iHOT-12 questionnaires, with scores being collected pre-operatively and at 6, 12 and 24 months post-operatively.

Nine hundred and eleven (911) patients were identified with twenty-seven (27) undergoing a triple osteotomy, the remaining patients underwent PAO. Mean age was 30.6 (15–56) years and 90% of patients were female. Seventy-nine (79) (8.7%) of patients had the procedure for acetabular retroversion leading to FAI

Statistical analysis, of all patients, showed significant improvement (p<0.001) for; iHOT-12 scores (+28 at 6-months, +33.8 at 12-months and +29.9 at 24-months)

Similarly there was significant improvement (p<0.001) in EQ-5D index (+0.172 at 6-months, +0.187 at 12-months and +0.166 at 24-months)

Pre-operatively, and at each follow-up time-period, raw scores were significantly better in the DDH group compared to the FAI group (p<0.05); however, the improvement in scores was similar for both groups.

For both scoring measures, univariable and multivariable linear regression showed poorer pre-operative scores to be strongly significant predictors of greater post-operative improvement at 6 and 12 months (p<0.0001).

Conclusions/Discussion

This study shows that pelvic osteotomy is a successful treatment for DDH and FAI, with the majority of patients achieving significant improvement in outcome scores which are maintained up to 24 months post-operatively. The patients with FAI have significantly reduced raw scores preoperatively and, perhaps, are functionally more limited.


Orthopaedic Proceedings
Vol. 99-B, Issue SUPP_12 | Pages 53 - 53
1 Jun 2017
O'Hara J McBryde C Gambling T
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Young Adult Hip [YAH] pathology is now better recognised and treated than decades ago. However, our patients have suggested to us that they encountered delays in recognition and referral.

For the past four years incoming referrals of YAH have been questioned away from the ROH clinic environment in groups of 100 incoming referrals by TS Gambling, Senior Lecturer in Psychology.

Time from onset of symptoms to clinic attendance; number of GP visits; Consultants seen before accurate diagnosis; validity of earlier investigations; severity and effects of symptoms on their daily lives and careers; social effects; body image; self-confidence; oxford hip scores.

The median age was 28 years; the mean delay in being seen at a YAH clinic was 8.3–8.6 years.

The mean number of consultants seen before the YAH clinic was 2.3 – 2.6.

Fewer than 5% were properly investigated by these consultants.

The mean oxford hip score was 30; in only 8% was it less than 20, the common level for hospital referral.

22% were unable to work. In 8% their career was unaffected.

Although 70% were working or pursuing a career, almost all required adaptations /redeployment to sedentary work/Long-term sickness testing employers' tolerance/Intermittent sickness/putting off promotion/ further education/part time working/change of career.

Only 8% were unaffected at work.

In addition, there were profound social effects upon self-esteem, body image, relationships, as well as comfort during sex.

These results do not make comforting news.

In addition to the above difficulties, all our patients expressed; Powerlessness; Frustration; Anger; Not being listened to; being unsupported; Undermined; Humiliation.

The family doctor/ GP services are poor at appreciating the disability in YAH patients.

YAH onset is characteristically at 19.5 years, just when youngsters are becoming independent and self-reliant.

The OHS is an invalid/misleading discriminator in these patients when considering referral.

The hospital orthopaedic service is poor at recognising and investigating YAH disease.


Orthopaedic Proceedings
Vol. 95-B, Issue SUPP_1 | Pages 195 - 195
1 Jan 2013
Robb C McBryde C Caddy S Thomas A Pynsent P
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Oxford hip and knee scores are being used by many heath care commissioners to determine whether individual patients are eligible for joint replacement surgery. Oxford scores were not designed for use in deciding whether patients are suitable for surgery and they are not validated as a triage tool. The aim of this study was to assess what effect these predetermined threshold Oxford Scores would have on a contemporary patient cohort.

An analysis was undertaken of 4254 pre-operative Oxford scores in patients who had already undergone either hip resurfacing, a total hip, total knee or unicompartmental knee replacement surgery at our institution between 2008 and 2011. We assessed how these scores would affect the decision making pathway determining which patients would be eligible for joint replacement surgery. We also evaluated the effects this would have on patients undergoing surgery in terms of gender, sex, age and type of arthroplasty.

22.4% hip resurfacings, 10.0% of total hip replacements, 7.5% total knee replacements and 11.0% unicompartmental knee replacements would have been declined on the Oxford Scores system. The selection criteria as set by the health care commissioners was found to be ageist as there was a bias against older patients obtaining surgery. There was a bias against different forms of arthroplasty, particularly those patients suitable for resurfacing or unicompartmental knee replacement. It was also sexist as it selectively excluded male patients from surgery.

Rather than using pre-operative Oxford scores to discern which patients are eligible for surgery, evaluation of patient factors which are reported to adversely affect the outcome of hip and knee replacement surgery, may offer a better solution to improving quality of care. Oxford scores are undertaken to benchmark a providers performance and not to decide on an individual's suitability for surgery.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXXV | Pages 5 - 5
1 Jul 2012
Jewell D McBryde C O'Hara J
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Purpose of study

This study is to determine the survival and outcomes of the Birmingham Interlocking Triple Pelvic Osteotomy. A dysplastic hip predisposes to early arthritis. The Triple Pelvic Osteotomy (TPO) is a joint-preserving option for the treatment of young adults with hip dysplasia. The long term success of the procedure is not known.

Patients and methods

The senior author has been performing Birmingham Interlocking Triple Pelvic Osteotomies for 18 years. The outcomes of the first 100 patients (117 TPOs) were reviewed using postal questionnaires, telephone interviews and radiograph review. The primary outcome measure of the study was the Kaplan—Meier survival curve for the TPO. Hip replacement or resurfacing were taken as failure points. The Oxford Hip Score (OHS) and University of California, Los Angeles (UCLA) score were used as secondary outcome measures for the surviving osteotomies. The pre-and post-operative acetabular index and centre-edge angles were measured from surviving radiographs.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IX | Pages 52 - 52
1 Mar 2012
Youssef B Revell M McBryde C Pynsent P
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Aim

To assess the survival of revision knee replacements at our institution and to identify prognostic factors that predict failure in revision knee surgery.

Materials and methods

This was a retrospective review of 52 patients who had undergone revision knee surgery as identified by hospital clinical coding. Patient demographics, physiological parameters, reason for revision, type of revision implant and last date of follow up were recorded from the medical records. Implant survival was analysed both from the index primary procedure to revision and from definitive reconstruction at revision to re-operation for any cause.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 549 - 549
1 Nov 2011
Bucknall V McBryde C Revell M Pynsent P
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Introduction: The Oxford hip score (OHS) instrument is used to assess pain and disability before and after hip arthroplasty and may be used as a standard for auditing pre and post-operative patients. It has been suggested that patients with a low pre-operative hip score (< 25th percentile) should be carefully assessed before surgical management is employed. This study aimed to determine the factors that influence a surgeon’s decision to undertake hip arthroplasty in patients with a low pre-operative hip score.

Methods: All patients who underwent hip arthroplasty over a two month period (n=121) were included. Of these, four pre-operative OHS questionnaires were missing. The remaining (117) were validated and those scoring below the published 25th percentile (58.3%) were selected (n=35), termed the ‘low-group’. Individual OHS responses scored 0–4 were examined (0 = no impairment and 4 = worst impairment) and the proportional differences between the responses for this group and the remaining 75% were investigated. The pre-operative radiographic Tönnis stage of osteoarthritis was determined.

Results: The median cohort OHS was 68.8% (IQR = 50–79%). Of the questions that scored highly, 59% were purely pain related, 14% function and 27% both. 66% of patients experienced moderate/severe pain and 31% suffered night pain. The ‘low-group’ never scored 4 (worst impairment) on questions concerning washing, transport, shopping, stairs and work. However, 57% scored 4 on questions encompassing a pain component. In all questions except donning socks and walking, the proportion of 4 in the ‘low-group’ was significantly different to the remainder of the cohort. Tönnis grade 3 (osteophytes and advanced loss of joint space) osteoarthritis predominated (49%).

Conclusion: Arthroplasty in patients with low pre-operative OHS is influenced mainly by pain affecting quality of life. Half of these patients also have advanced features of osteoarthritis on radiographic assessment despite the low scores.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_IV | Pages 548 - 548
1 Nov 2011
Shears E McBryde C O’Hara J Pynsent P
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Introduction: A proposed benefit of hip resurfacing is straightforward revision. This study assesses the outcome of revision in a large series of failed resurfacings.

Methods: A consecutive series of 84 revisions of metal-on-metal hip resurfacings was analysed. The cohort consisted of 51 (61%) women and 33 (39%) men with a mean age of 48.0 years (range: 15.1–75.3 years) at primary resurfacing. The underlying diagnosis was primary osteoarthritis in 40 (48%) patients, developmental dysplasia of the hip in 13 (15%), avascular necrosis in 9 (11%) and slipped upper femoral epiphysis in 7 (8%).

Mean patient age at first revision was 50.8 years (range: 18.4–75.9 years), at a median of 1.8 years (25th percentile 0.03 years, 75th percentile 4.6 years) after the primary operation. 29 (35%) resurfacings were revised for aseptic loosening, 23 (27%) for periprosthetic fracture, 8 (10%) for component malalignment, 8 (10%) for pain alone, 4 (5%) for infection, 4 (5%) for avascular necrosis and 4 (5%) for instability.

Results: At a mean follow-up of 4.6 years (range: 1.0–8.2 years) after the first revision, 10 (12%) of the revised hips had undergone a second revision procedure. 6 men and 3 women required re-revision (data not available for 1 patient). The reasons for the first revision were acetabular malalignment (n=2), femoral neck fracture (n=2), aseptic loosening (n=2), avascular necrosis (n=1), instability (n=1) and pain alone (n=1). The second revision was required at a mean of 3.4 years (range: 0.4–6.3 years) after the first.

Discussion: This study suggests that revisions of hip resurfacing for acetabular malalignment may be at increased risk of subsequent re-revision (2 of 7 patients, 29%). Revision for other causes appears to have better survival in the short to medium term.


Orthopaedic Proceedings
Vol. 93-B, Issue SUPP_I | Pages 38 - 38
1 Jan 2011
McBryde C Shears E Pynsent P Treacy R
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We report the survival at ten years of 173 consecutive Birmingham Hip Resurfacing’s implanted between August 1997 and August 1998 at a single institution. Failure was defined as revision of either the acetabular or femoral component for any reason during the study period.

The survival at the end of ten years was 96.5% (95%c. i. 89.1 – 99.5%) The mean age of the patients at implantation was 50 years (range 15 – 75). There were 124 (72%) male cases and 49 (28%) female cases. 123 (71%) cases had the diagnosis of osteoarthritis, 9 osteonecrosis, 5 rheumatoid and 3 DDH. The posterior approach was used in 154 (89%) cases and anterolateral in 19 (11%). Cases were performed by 5 different surgeons.

There were 5 revisions, 9 unrelated deaths and 18 were lost to follow-up beyond 5 years. Two revisions occurred for infection (6 months and 2 years). A revision at 3.5 years for acetabular loosening and two further at 6.4 and 7.9 years due to avascular necrosis of the femoral head and collapse were performed. No other revisions are impending. The median pre-operative oxford hip score was 61% (IQR 48–73) and the median 10 year score was 7% (IQR 0–31) for 110 completed forms.

Further analysis of the total resurfacing database at this institution of 2775 cases was performed. Cox-proportional hazard analysis identified that component size and pre-operative diagnosis were significantly associated with failure. Although females may initially appear to have a greater risk of revision this is related to differences in the size and pre-operative diagnosis between the genders. This study confirms that hip resurfacing using a metal-on-metal bearing of known provenance can provide a solution in the medium term for the younger more active adult who requires surgical intervention for hip disease.


Orthopaedic Proceedings
Vol. 92-B, Issue SUPP_III | Pages 389 - 389
1 Jul 2010
McBryde C Theivendran K Treacy R Pynsent P
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Introduction: Hip resurfacing has gained popularity for treating young and active patients with arthritis. Recent literature has reported increase revision rate amongst females as compared to males undergoing resurfacing. The aim of this study is to identify any differences in survival or functional outcome between male and female patients treated with metal-on-metal hip resurfacing.

Methods: All procedures performed between July 1997 to July 2003 were extracted from the database and grouped based on gender. 1266 patients (1441 hips, 582 female and 859 male patients) were identified. The preoperative diagnosis, Oxford hip score, component size, post operative complications and revisions were recorded. Failures included revision of either the femoral or acetabular components.

Results: The mean follow up was 5.5 years. There were 52 revisions in total (30 in female and 22 in male group). The 8 year survival in the male and female groups were 96.1% and 91.5% respectively which is significantly different (p=0.0006). The size of the femoral component was significantly associated with revision (p=0.0008). Cox proportional hazard modelling including gender, aetiology and femoral component size identified a diagnosis of osteoarthritis reduced the risk of revision of 0.2 times (p=0.0004). However, SUFE was significantly associated 5.57 times increased risk of revision (p=0.0019). With every millimetre increase in head size there was a reduction in risk of revision of 0.89 (p=0.0098). By inclusion of all variables in this model gender was found not to be significantly associated with failure.

Conclusion: This study demonstrates that although females may initially appear to have a greater risk of revision this is related to differences in the femoral size and pre-operative diagnosis between the genders. Patient selection for resurfacing is best made on size and diagnosis rather than gender.


Orthopaedic Proceedings
Vol. 91-B, Issue SUPP_I | Pages 17 - 17
1 Mar 2009
McBryde C Dhene K Pearson A Pynsent P Treacy R
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Metal-on-metal hip resurfacing is increasingly common. Patients suitable for hip resurfacing are often young, more active, may be in employment and may have bilateral disease. One-stage bilateral total hip replacement has been demonstrated to be as safe as a two-stage procedure and more cost effective. The aim of this study was to compare the in-patient events, outcome and survival in patients undergoing one-stage resurfacing with a two-stage procedure less than one-year apart.

Methods. Between July 1994 and August 2006 a consecutive series of 93 patients underwent bilateral hip resurfacing within a year. 34 patients in the one-stage group. 44 patients in the two-stage group. The age, gender, diagnosis, ASA grade, total operative time, blood transfusion requirements, medical complication, surgical complications, length of stay, duration of treatment, revision and Oxford hip scores were recorded.

Results. There were no significant differences in age, gender, ASA grade between the one-stage and the two-stage. There were 4 minor complications in the one stage group and 5 in the two-stage group. All patients that suffered a complication made a full recovery. There was no significant difference in the blood transfusion requirements. The mean anaesthetic time was 136 minutes in the one stage group and 92 minutes in the two-stage group with a significant mean difference of 44 minutes(95% c.i. 31–52). The mean total length of hospital stay was 11 days in the one-stage group and 16 days in the two-stage group with a significant mean difference of 5 days(95\% c.i. 4.0–6.9). The mean difference in length of treatment time of 6.5 months was significant(95\% c.i. 4.0–9.0).

No patients have undergone a revision procedure during the study period and no patient is awaiting revision surgery.

Conclusions. This study demonstrates no detrimental effects when performing a one-stage bilateral metal-on-metal hip resurfacing in comparison to a two-stage procedure. There are advantages of a one-stage procedure over a two-stage procedure for bilateral disease. Total hospital stay is reduced by 31.3% and the mean length of treatment is reduced by 50.0%. These benefits do not appear to come at the cost of increase complications. The complication rate in both groups was very low and all of the complications were short-term and are unlikely to have any bearing on the longevity of the prosthesis.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_II | Pages 211 - 211
1 May 2006
Thomas A McBryde C Pynsent P
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Metal on metal hip resurfacing was introduced in 1992 by Derek McMinn initially using an all cementless device and then an all cemented device. A hybrid resurfacing with a cemented femoral component and a cementless acetabular component was introduced in 1994. The manufacturer of the hybrid hip resurfacing was changed in 1996. Since 1997 the Birmingham hip resurfacing has been in continuous use.

The device is approved by NICE (National Institute for Clinical Excellence) for use within the NHS in patients with Osteoarthritis of the hip. The device is not yet approved for use in patients with Rheumatoid Arthritis and other types of inflammatory arthritis. There are concerns regarding bone quality in rheumatoid patients, which may result in a high incidence of component loosening or femoral neck fracture. Conventional total hip replacement is a successful procedure in inflammatory arthritis however with modern treatments producing increased activity levels there are concerns about polyethylene wear.

The author has performed metal on metal hip resurfacing in patients with inflammatory arthritis over the past 12 years. A total of 170 patients have been operated on with 198 resurfacings. 33% of patients have a diagnosis of some type of inflammatory arthritis. The outcomes have been assessed using Oxford hip scores and long term clinical and radiological review. Our results indicate that there is a minimal risk of femoral neck fracture and a minimal risk of component loosening when the device is used with this approach in patients with inflammatory arthritis.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 58 - 58
1 Mar 2006
McBryde C O’Hara J Pynsent P
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This study reports the early results of Birmingham Hip Resurfacing in a group of patients less than 25 years of age. We assessed over a period of 5 years all patients who underwent hip resurfacing who were under the age of 25. Thirty-eight patients underwent 43 hip resurfacing procedures for a variety of diagnoses. This included 15 with Developmental Dysplasia of the Hip (DDH), 13 with Osteonecrosis (ON) of the femoral head, and 7 with End-stage Spastic Hip Disease (ESSHD). We assessed complications, failure and revision rates. Patients completed co-op and oxford hip scores and both clinical and radiographic assessments. At a follow-up of a maximum of 5 years the survival rate was 93% with a further 7% showing radiographic features of failure. Thirteen hips (30%) had a femoral osteotomy at the time of resurfacing allowing correction of length and rotation with no apparent increase in complications. Those who required revision were successfully converted to metal- metal total hip replacement. Our results report the first use of this type of prosthesis in a group of patients under the age of 25 and demonstrate comparable results to standard treatments at this early stage. This study supports the use of hip resurfacing as alternative to conventional treatments for this complex group of patients.