Identifying the optimal agent for irrigation for periprosthetic joint infection remains challenging as there is limited data. The ideal solution should have minimal cytotoxicity while maintaining bactericidal activity. We developed a novel activated-zinc solution containing zinc-chloride (ZnCl2) and sodium-chlorite (NaClO2). The purpose of this study was 1.) to investigate the antimicrobial efficacy of 2 concentrations (“CZ1”, “CZ2”) against The study was conducted and reported in accordance to ARRIVE guidelines. We created twenty-four 1.5cm wounds on the back of a Yorkshire-cross pig. Wounds were inoculated with standardized Aim
Method
We report the largest multicentre series analysing the use of bone scans investigating painful post-operative Total Knee Replacements (TKR). We questioned the usefulness of reported scintigraphic abnormalities, and how often this changed subsequent management. 127 three-phase bone-scans were performed during a two-year period. Early and late flow phases were objectively classified. Reported incidences of infection and loosening were determined. Reports were subjectively summarised and objectively analysed to establish the usefulness of this investigation. Eight cases were excluded. Scans were classified as: 33% (39) normal, 53% (63) as possibly abnormal, 6% (7) probably abnormal, and 8% (10) as definitely abnormal. Thirteen patients (11%) underwent revision TKR surgery. Intra-operative analysis revealed loosening of one femoral component, and massive metallosis of the patella in another. Cultures were negative in all cases. The sensitivity and specificity of a definitely abnormal investigation in predicting need for revision surgery was 23% and 82% (respectively). High instances of ambiguously reported abnormalities were observed. This investigation has no role to play in the routine investigation of a painful TKR. It is unnecessary in investigation of periprosthetic infection and should not be used in a routine assessment of a painful TKR. If used it should be limited until an experienced revision surgeon has made a full assessment.
Sledging related minor and major injuries represent a significant workload at ski-area medical centers across the world. Although safety rules exist, they are seldom obeyed or enforced. We set out to determine the incidence of sledging related injuries, identifying trends and causative factors at a busy New Zealand Ski resort. All sledging related injuries presenting during a 70-day period were prospectively reviewed. Patient demographics, mechanism, diagnosis, and treatment were recorded. Sixty patients were identified, mean age 10 years, range 4-30 years. Injuries comprised; collisions with sledgers (21), collision with wall (14) and falling from sledge (14). Site of injury included head (36), lower limb (18), spine (9), upper limb (7), and abdomen (2). Fractures included; femur (1), tibia (1), fibula (1), ankle (2), cuboid (1), clavicle (2), scaphoid (1). One 9-year-old patient sustained a serious intracranial haemorrhage, with subsequent permanent neurological sequelae. Sledging related injuries are mostly minor, however significant major injuries do occur requiring intervention at a secondary center. The potential for serious morbidity is evident. Recommendations supporting safety improvement measures does exist, however most were not implemented by the study cohort examined. The use of basic cycling helmets would seem an appropriate minimum level of protection, and greater sledging safety awareness should be encouraged.