Mesenchymal stem cells from human semitendinosus and gracilis tendons (TSPCs) could be a promising MSCs resource for tissue-engineering application. In comparison to adipose-derived stem cells, TSPCs possess similar stem-cells properties and a higher chondrogenic differentiation potential. Mesenchymal stem cells (MSCs) isolated from bone marrow (BMSCs) or adipose tissue (ASCs) have been deeply characterised for their usefulness in musculoskeletal tissue regeneration. However, other potentially valuable MSCs sources have been recently proposed. The goal of this study was to isolate MSCs from human semitendinosus and gracilis tendons (TSPCs, tendon stem progenitor cells) and to compare their features with that of human ASCs.Summary
Introduction
