When inserting a lag-screw across an arthrodesis, stress is concentrated under the screw head risking asymmetrical force distribution and fracture of the cortical bone bridge. The IO FiX (Extremity Medical, NJ USA) is a new intraosseous device comprising an X-Post on one side of and parallel to the arthrodesis and a lag-screw inserted through the head of the X-Post which reinforces the cortical bone bridge. The X-Post behaves as an internal washer improving force distribution across the arthrodesis. Being intraosseous, near to the neutral axis of bend also means the device is fatigue-resistant and soft tissue irritation is reduced. The IO FiX has not been independently verified and therefore we analysed its performance in a human cadaveric ankle model. Our null hypothesis was there is no difference in force generation and contact area in an ankle arthrodesis when the IO FiX is compared with partially-threaded lag-screws. We used ten randomized cadaver ankles with a mean age of seventy-one years (44–84 years) prepared with flat arthrodesis cuts. A Tek-scan (Boston, USA) pressure transducer was used to measure force and contact area produced when the IO FiX was compared with a standard lag-screw and washer. The median average force in the IO FiX group was 3.95 kg and 2.35 kg in the lag-screw group ( Our results suggest the IO FiX improves force generation and contact area across the arthrodesis. With the theoretical advantages of reduced soft tissue irritation and a lower risk of fatigue failure, the IO FiX offers a significant advantage compared with traditional fixation techniques.