Introduction: In order to investigate the relationship between the degeneration of the acetabular cartilage and the radiological staging of osteonecrosis of the femoral head, the following study was performed.

Materials and Methods: Acetabular cartilage with sub-chondral bone was taken from the superior dome from 34 hips from 30 patients undergoing total hip arthroplasty due to osteonecrosis of the femoral head. The specimens were stained with hematoxylineosin and safranin-O, and were evaluated as to the thinning of cartilage, fibrillation, clefts, and proliferation of chondrocytes. There were 18 females and 12 males with an average age of 49 years. We used the radiological staging system proposed by the working group of the Specific Disease Investigation Committee under the auspices of the Japanese Ministry of Health, Labor and Welfare. There were eight hips in stage IIIA disease (collapse of the femoral head less than 3 mm), 19 hips in stage IIIB disease (collapse 3 mm or greater), and seven stage IV disease hips.

Results: All 34 specimens showed histological abnormalities. In eight stage IIIA hips, six hips were mild and two were moderate histological degeneration. In 19 stage IIIB hips, five hips were mild, six were moderate, and eight had severe arthrosis. Seven stage IV hips had severe arthrosis.

Discussion: Although the radiographs cannot demonstrate early degeneration of cartilage, degenerative changes were present in all stage III hips. Histological degenerative changes in stage IIIB hips were more severe than those in stage IIIA hips. These findings should be kept in mind in treating patients with osteonecrosis of the femoral head.

[Objectives] Hallux valgus, dorsal sublaxation or dislocation of metatarsophalangeal joints and clawing of the lateral toes are seen frequently in patients with rheumatoid arthritis (RA). Resection arthroplasty of the metatarsophalangeal joints (MTP joints) are widely used to correct these forefoot deformities and the clinical results are almost good. However lateral toes tend to displace dorsally and painful callosity tends to recur. We used the metatarsal shortening offset osteotomy for shortening and dorsal/medial displacement of the prominent metatarsal head. In this report, we introduce the surgical techniques of shortening offset osteotomy and postoperative changes of plantar pressure measured with F-scan system (Tekscan, Inc. ), and review the short term result during 1 to 4 year follow-up.

[Materials and Methods] This study involved 26 feet of 18 patients with RA which were performed with the metatarsal osteotomy for lateral toes and followed more than 1 year (average follow-up 29 months, range 14–46 months). The average age of the 17 women and 1 man was 61 years (range, 51–77 years). The mean duration from the onset of RA to operation on the forefoot was 17 years (range, 7–42 years). Skin incision was placed on the dorsum of the foot and the extensor digitorum brevis and longus were severed (or elongated). After reposition of MTP joint, transverse osteotomy of distal fifth of the lateral metatarsal bone was performed with resection of few millimeters length metaphysial bone. Cortical bone of the distal end of the proximal stump was chiseled into a small rod between two ditches with rongeur and then the rod was put into medullary canal mortise of distal stump. This procedure make offset shift of metatarsal head medially or dorsally. Swanson implant arthroplasty, distal osteotomy was performed on the great toe. Postoperative clinical and radiological results were evaluated with AOFAS rating system. We measured dynamic plantar pressure before and one year after operation in one representative case.

[Results] At the time of follow-up, the mean AOFAS score was 80 points (59–95) and the mean pain score was 36 points. The recurrence of painful callosity was one case. Nevertheless, the range of motion of the MTP joint remained low: 30 degrees and less in 16 feet (62%) including 3 bony ankylosis of MTP joints. There was no nonunion case. [Discussion]

Resection arthroplasty has been accepted as the treatment of choice for forefoot deformities in RA patients. Recent advance of drug therapy against RA encouraged us to preserve the joint in correction of forefoot deformities. Our technique aimed at preservation of the function of the MTP joints and is suitable for mild deformities in which only one or two rays are involved. Furthermore it is easy to correct the deformity of spray foot and reduce the plantar prominence of metatarsal head. This study revealed the good clinical result in short term follow-up. Although the long term result must to be waited, this method is one of recommendable options for RA patients with forefoot deformities.

We developed a new type of bioactive bone cement, CAP (Hydroxyapatite composite resin; composed of 77% w/w hydroxyapatite granules and bisphenol-A glycidyl methacrylate-based resin) for bony defect filling. Elastic modulus of CAP is similar to a cortical bone, while it is injectable before hardening and physiologically bonding with bone in 4 to 8 weeks. We present a new method of treatment for unstable Colles’ fracture with this material in clinical use.

Experimental comminuted Colles’ fracture was produced in three fresh frozen cadavara. Fracture was reduced and fixed percutaneously with K-wires. 4.5mm drill hole was opened on the radial cortex 3cm proximal to the fracture site. Comminuted fragments were pushed-up to the subchondral area with a blunt rod and CAP was injected through the same way. After cement hardening, K-wires were removed. X-ray photos were examined before fracture, after fracture and after reconstruction with CAP, in order to evaluate the shape of the radius. CT was examined to evaluate the placement of CAP.

Radiographic parameters of radii were well recovered after reconstruction with CAP. Over correction of the radial length was observed in one bone but good reduction was generally achieved (Table). This means realignment of the distal radioulnar joint, which results in good outcome clinically. In transverse section of CT, 41 to 69% (average 55%) of subchondral area was filled with CAP. Filling of CAP was better in an osteoporotic bone. These results show the usefulness of this material for treatment of unstable Colles’ fracture especially in osteoporotic patients.