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Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_II | Pages 162 - 162
1 Apr 2005
Harvie P Ostlere S Teh J McNally E Clipsham K Burston B Pollard T Carr A
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The purpose of this study was to investigate the role that genetics play in the aetiology and symptomatology of full thickness tears of the rotator cuff.

From a retrospective, cohort study of 205 patients diagnosed with full thickness rotator cuff tears, we determined, using ultrasound, the prevalence of full thickness tears in their 129 siblings. Using 150 spouses as controls, the relative risk of full thickness rotator cuff tear in siblings v controls was 2.42 (p< 0.0001, 95 % CI 1.77 to 3.31). The relative risk of symptomatic full thickness rotator cuff tear in siblings v controls was 4.65 (p< 0.0001, 95 % CI 2.42 to 8.63).

The significantly increased risk for tears in siblings implies that genetic factors play a major role in the development of full thickness tears of the rotator cuff.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_II | Pages 164 - 164
1 Apr 2005
Matthews T Smith S Urban J Carr A
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Aim To determine if tissue metabolism varies in supraspinatus tendons with distance from the edge of the rotator cuff tendon tear and also with differing size of tear.

Background Tissue metabolism can be assessed by measuring oxygen and nitrous oxide concentrations within the tissue. Viable tendon tissue consumes oxygen and contains nitrous oxide (used in the general anaesthetic) from the blood stream. Non-viable tendon tissue will not consume oxygen but will contain nitrous oxide.

Methods Oxygen and Nitrous Oxide concentrations were measured amperometrically using silver needle microelectrodes.

The needle was inserted into the supraspinatus tendon of patients with massive, large, medium and small full thickness rotator cuff tears and patients with partial thickness and no tears. Patients undergoing open stabilisation were used as controls. Measurements were made at a number of quantifiable points from the tendon edge to allow the creation of a topographical map of tissue metabolism. Oxygen consumption was calculated using measured oxygen and nitrous oxide levels at each point.

Results In patients with rotator cuff tears oxygen consumption was significantly lower near to the edge of the tear.

Patients with impingement syndrome but no evidence of a rotator cuff tear also showed a decreased level of oxygen consumption in the anterior part of supraspinatus, but this was significantly higher than the levels seen in the torn tendon.

The control group showed no significant alteration in oxygen levels

Conclusion Patients with rotator cuff tendon tear demonstrate significantly reduced levels of tissue metabolism. This reduction in tissue viability is significantly greater at the edge of the tear and in larger tears. Patients with intact tendons and impingement syndrome also demonstrate minor reduction in tissue tendon viability compared with controls.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_II | Pages 163 - 163
1 Apr 2005
Little C Graham A Ionanides G Carr A
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A systematic review of the English language literature has suggested that the performance of linked and unlinked elbow replacement implants differ in terms of function, survival and mode of failure; however, in this review, only one comparative series using contemporary implants was identified. We have performed a cohort study of Kudo, Souter-Strathclyde and Coonrad-Morrey elbow replacements performed at a single centre by or under the direct supervision of a single Consultant shoulder and elbow surgeon to see if these findings were reflected in clinical practice. The first forty implantations in patients with Rheumatoid arthritis for each device have been reviewed with respect to surgical complications, elbow function and implant survival. The follow-up was shorter for the Coonrad-Morrey cohort. In terms of pain relief and range of motion, the performance of the implants was comparable. The mode of failure was different, with no dislocations/ instability seen with the linked Coonrad-Morrey implants. The loosening rate of the Coonrad-Morrey implants (both clinical and radiographic) was lower, albeit with a shorter follow-up period. The loosening rates seen in this series were higher than those previously reported in the English language literature. We conclude that the functional performance of the implants, at similar stages of the surgical learning curves, are similar in patients with Rheumatoid arthritis, but that use of a linked implant removes the risk of post-operative instability and may reduce the risk of the radiographic and clinical loosening.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_II | Pages 162 - 162
1 Apr 2005
Harvie P Pollard T Carr A
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The purpose of this study was to investigate the association of endocrine disease with calcific tendinitis and the effects that such disease has on its natural history.

A retrospective observational cohort study of 102 consecutive patients (125 shoulders) with calcific tendinitis is presented. Seventy-three (71.6 %) female, 29 (28.4 %) male. Compared with population prevalences, significant levels of endocrine disorders were found in our study cohort. Sixty-six patients (81 shoulders, 62 female (93.9 %), 4 male (6.1 %), mean age 50.3 years) with associated endocrine disease were compared with 36 patients (44 shoulders, 11 female (30.6 %), 25 male (69.4 %), mean age 52.4 years) without endocrine disease. The endocrine cohort were significantly younger than the non-endocrine cohort when symptoms started (mean 40.9 years and 46.9 years respectively, p=0.0026), had significantly longer natural histories (mean 79.7 months compared with 47.1 months, p=0.0015) and a significantly higher proportion underwent operative treatment (46.9 % compared with 22.7 %, p=0.0014).

Disorders of thyroid and oestrogen metabolism may contribute to calcific tendinitis aetiology. Classifying calcific tendinitis into Type I idiopathic and Type II secondary or endocrine-related aids prognosis and management.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_I | Pages 4 - 4
1 Mar 2005
Spencer J Pollard T Carr A Gibbons C Athanasou N
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Between 1972 and 2002 74 patients were treated under the combined care of the orthopaedic oncology service and lymphoma clinic with primary bone lymphoma. We reviewed the seventeen cases affecting the upper limb (23%). Of the seventeen patients nine remain alive. Assessment of the patient’s clinical presentation, histopathological definition, treatment and function outcome was made. The nine survivors were assessed clinically and with the Oxford shoulder score and the Toronto extremity salvage score.

Average time from first presentation to diagnosis was 7 months. All seventeen were diagnosed as a B –cell non-Hodgkin’s lymphoma, fifteen cases were high grade and two cases were low grade. The scapula was involved in six, humerus eight and clavicle three cases. Seven patients sustained pathological fractures three of which were at presentation; of these two were treated surgically. Eight patients have subsequently died of their disease. Functional outcome in surviving patients after medical treatment was very good with average TESS score of 79% (52%–99%) and OSS of 27 (12–52).

The presentation of lymphoma of the shoulder girdle may mimic benign shoulder conditions and lead to a delay in radiological and histopathological diagnosis. Pathological fracture is a common presentation and complication of treatment, however these fractures have a high chance of healing with medical treatment alone. Although shoulder stiffness remains a problem following medical treatment, overall upper limb function is good. There is little evidence that these patients require surgery in the short to medium term.


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_II | Pages 196 - 196
1 Jul 2002
Graham A Karatzas G Carr A
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From 1985 to 1998 we used the Souter implant for elbow replacement in the rheumatoid population. We have followed this cohort prospectively, and present simple outcome measures including initial pain relief, early complication rates, radiological changes with time, and survivorship.

We performed 71 Souter elbow replacements in 62 rheumatoid patients (51 female, 11 male). The average age at surgery was 61 (range 38–79). All patients had end stage arthropathy. Early results and complications were assessed in all patients. Subsequently, ten cases were revised for loosening, and eight patients (10 elbows) died before recent follow up, leaving 51 cases for long term study. Clinical and radiological data were obtained.

On early follow up, 94% had no or minimal pain. Thirty-one percent suffered a complication. Overall, 18% cases had ulnar nerve problems and 7% dislocated in the first year. Seven percent had wound problems, including two deep infections. At mean long term follow up of 6 years (range: 2–15 years) there were high rates of satisfaction in patients with retained prostheses. Progressive radiolucency around the humeral component was common and treated expectantly. Late instability was not seen. Pain relief was maintained.

There have been few long-term reports on the Souter elbow replacement. This group of patients from a single centre has been followed prospectively. Infection and ulnar nerve complications are comparable with other series, and are less related to prosthesis. The rate of humeral component loosening in this series is high. The rate of dislocation, however, is low. This prosthesis sacrifices stability to transmit forces through the soft tissues. Although stability is acceptable there is no beneficial reduction in loosening.


Orthopaedic Proceedings
Vol. 84-B, Issue SUPP_II | Pages 191 - 191
1 Jul 2002
Karatzas G Graham A Carr A
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The purpose of this study was to evaluate the outcomes of treatment of rheumatoid elbows with Kudo Total Elbow Replacements.

Between 1993–1997 we performed 39 Kudo Total Elbow Replacements in 35 patients with Rheumatoid Arthritis, aged 39–81 years old (mean age: 60,7 yrs). Eleven patients (13 elbows) were male and 24 (26 elbows) were female. Twenty-eight (28) replacements were performed on the right side and eleven (11) on the left. All the patients were evaluated clinically (pre-op and post-op, using Mayo score system) and radiographically. In seven elbows another procedure (radial head excision (three), radial head excision & synovectomy (three), arthroscopy & interposition arthroplasty(one)) had been performed previously for the rheumatoid arthritis. Eight elbows seemed to have ulnar nerve problems pre-op. We followed-up 31 patients (35 elbows). Mean follow-up was 5years (range: 4–8 years).

The pre-operative pain had been reduced significantly in almost all patients. In the majority, the movement had also been improved post-operatively. Two elbows were unstable (one subluxated, one dislocated). Both presented early postoperatively. Only one patient developed a postoperative ulnar nerve problem and that resolved. One elbow had a delay in wound healing. Radiolucency appeared around both the humeral and ulnar components in five elbows, around humeral component in two and around ulnar component also in two. Five elbow replacements were revised. Four of them due to aseptic loosening and one due to instability problem (dislocation). No deep infection was noticed in any elbow.

In our hands, Kudo Elbow Replacements seemed to have aseptic loosening rates comparable to other series and low dislocation rates.