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Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 92 - 92
1 Mar 2008
Van Houwelingen A Panagiotopoulos K Schemitsch E Richards R McKee M
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Thirty-eight patients with nonunion of the humeral shaft underwent a comprehensive assessment including completion of three patient-based functional outcome surveys as well as the determination of the Constant shoulder and Mayo elbow scores. Treatment consisted of compression plating with or without bone grafting. Smokers were found to have significantly longer time to union as compared to nonsmokers (25.1 weeks vs. 16.2 weeks, p< 0.001). Our results also demonstrated that increased time to union had a significant negative effect on the patient-reported functional outcome scores.

To evaluate the functional outcome and identify prognostic factors that influence the healing time of surgically treated humeral shaft nonunions.

Time to consolidation of operatively treated humeral shaft nonunions was significantly longer in smokers versus non-smokers. Time to union was negatively associated with the patient-reported functional outcome scores.

The long-term functional outcome following surgical treatment of humeral shaft nonunions is dependent upon the time to consolidation. Smoking is a significant remediable risk factor for delayed union following surgical repair of humeral shaft nonunion.

We identified thirty-eight patients (mean age fifty-five years) treated surgically for nonunion of the humeral shaft at a mean follow-up of sixty months. All patients underwent a comprehensive assessment including the completion of the SF-36, the DASH, the SMFA and the determination of the Constant shoulder and Mayo elbow scores. Seventeen (44.7%) patients were classified as ‘smokers’ and twenty-one (55.3%) were ‘non-smokers’. All nonunions united with a mean time of 16.2 weeks for non-smokers and 25.1 weeks for smokers (p< 0.001). Time to union was negatively associated with the Physical Function portion of the SF-36 (p=0.01), the DASH (p=0.01), and the Arm and Hand Function part of the SMFA (p=0.005). The only other factor that had a significant negative effect on the functional outcome scores was the presence of one or more comorbid factors (SF-36, p< 0.001; DASH, p< 0.001; SMFA, p< 0.001). Patient-oriented and surgeon based scores were found to correlate well (range r=0.545 to r=0.916, p< 0.001 for all combinations).


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 73 - 73
1 Mar 2008
Laflamme Y Borkhoff C Bodavula V Cogley D Stephen D McKee M Schemitsch E Kreder H
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The purpose of this study was to evaluate functional outcome in patients with combined pelvic and acetabular fractures and to identify factors associated with outcome. One hundred and fifteen patients were identified. 63% were male; mean age was thirty-seven years; mean ISS was thirty. Three patients died from their injuries. At a mean follow-up of 3.5 years, patients exhibited profound functional deficits compared to the normal population. Those with an acetabular fracture involving the posterior wall or an associated lower extremity injury have a particularly poor prognosis. Combined pelvic and acetabular injuries are associated with high mortality and functional morbidity irrespective of treatment.

To evaluate functional outcome in patients with combined pelvic and acetabular fractures and to identify factors associated with outcome.

Combined pelvic and acetabular injuries are associated with high mortality and functional morbidity irrespective of treatment.

These results will allow us to further investigate which injury is dictating prognosis in the combined injury – the pelvic or the acetabular fracture.

One-hundred and fifteen patients with combined pelvic and acetabular injuries were identified at a level One trauma centre. 63% were male; mean age was thirty-seven years (13–88); mean ISS was thirty (16–75). Three patients died from their injuries. 16% involved bilateral pelvic fractures; 7% bilateral acetabular fractures; and for 2%, both were bilateral. 64% were Tile B and 34% were Tile C. Most acetabular fractures involved the anterior column or both column. Only 18% were treated with ORIF for both injuries. 25% had ORIF of their acetabulum and 14% had ORIF on their pelvis. Sixty-five patients completed validated functional outcome questionnaires at a mean follow-up of 3.5 (one to eleven) years. Patient function was significantly compromised with a mean MFA score of 33.8 (SD 21.8). Function was worse for all 8 SF-36 domains and the two component scores compared to the health status of the Canadian normal population (p< 0.001). Those individuals with an acetabular fracture involving the posterior wall or an associated lower extremity injury have a particularly poor prognosis. There was no relationship found between treatment or the pre-defined stability groups and functional outcome.

Funding: Grant funded from AO/ASIF


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_I | Pages 47 - 47
1 Mar 2008
Pirani S McKee M
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In five teaching hospitals, seventy-two patients with seventy-three bicondylar tibial plateau fractures were prospectively randomized by envelope to treatment either by AO methods (group A) or ring fixator methods (group B). Outcome measures included clinical and radiographic parameters, & HSS knee scores.

Results: Re-intervention was necessary within six months in ten group A & seven Group B patients. Forty-three procedures were performed (thirty-three Group A-ten Group B) I& D 12- 3: STSG 3-0: Quadricepsplasty 1-0; Manipulation 2–4; Muscle flap 2–0; Above knee amputation 1–0; Revision ORIF 5–1; Revision Rings 0–1; Bone graft 2–1; Bead pouch 3-0; Synovectomy 1-0; Sequestrectomy 1-0.

More patients had more septic and wound complications resulting in more need for re-intervention following ORIF.

Conclusion. For bi-condylar tibial plateau fractures (OTA 41.C) six-month HSS scores are significantly higher after treatment with Ring Fixator methods. Reintervention rates for deep sepsis/wound problems are higher with AO methods. Wound and infection complications occurring after AO treatment are more severe and require multiple procedures for control.

We have conducted a prospective randomized trial to determine the outcomes of treatment by

Open reduction and internal fixation or

Closed reduction and ring fixation for the treatment of bi-condylar tibial plateau fractures (OTA 41.C)

We report our early findings on re-intervention rates for complications.

In five teaching hospitals, seventy-two patients with seventy-three bi-condylar tibial plateau fractures were prospectively randomized by envelope to treatment either by AO methods (group A) or ring fixator methods (group B). Outcome measures included clinical and radiographic parameters, & HSS knee scores. Randomization gave the following demographics

Re-intervention was necessary within six months in ten group A & seven Group B patients. Forty-three procedures were performed (thirty-three Group A-ten Group B) I& D 12- 3: STSG 3-0: Quadricepsplasty 1-0; Manipulation 2-4; Muscle flap 2-0; Above knee amputation 1-0; Revision ORIF 5-1; Revision Rings 0-1; Bone graft 2-1; Bead pouch 3-0; Synovectomy 1-0; Sequestrectomy 1-0.

More patients had more septic and wound complications resulting in more need for re-intervention following ORIF.

For bi-condylar tibial plateau fractures (OTA 41.C) six-month HSS scores are significantly higher after treatment with Ring Fixator methods. Reintervention rates for deep sepsis/wound problems are higher with AO methods. Wound and infection complications occurring after AO treatment are more severe and require multiple procedures for control.

Please contact author for pictures and/or diagrams.


Orthopaedic Proceedings
Vol. 88-B, Issue SUPP_I | Pages 163 - 163
1 Mar 2006
Waddell J Schemitsch E McKee M McConnell A James S
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Introduction and Aims: Open femoral fracture is a serious injury. We have asked the question: do open femur fractures in polytrauma patients correlate with higher injury severity scores, increased length of stay and higher mortality rates than in closed femur fracture polytrauma patients.

Method: We undertook a retrospective review of a prospectively gathered trauma database at a Level 1 trauma centre. We identified multiple-injured patients with femur fractures who presented in a 36 month period. The cases were divided into 2 groups; open femur fractures (n=33) and closed femur fractures (n=80). Data was collected on demographics, precipitating event, length of stay spent in the ICU, number of associated injuries, ISS, AIS for affected systems, number of femoral surgeries and disposition. Data was analyzed using parametric statistical tests with a significance level of 0.05.

Results: Our analysis revealed that an average, patients in the open femur fracture group spent 8 + 9 days in ICU, sustained 4 + 1 associated injuries, underwent 2 + 1 femoral surgeries, had an ISS of 29 + 13, and died of their injuries in 30.3% of cases. Patients in the closed femur fracture groups spent 8 + 9 days in ICU, sustained 4 + 1 associated injuries, underwent 1 + 1 femoral surgeries, had an ISS of 29 + 14, and died of their injuries in 12.5% of cases. One-way ANOVA showed no statistically significant difference between groups in terms of time spent in ICU, ISS and number of associated injuries. The average number of surgeries was significantly greater in the open femur fracture group (p-value 0.000). A Chi-squared analysis of disposition indicated that patients with femur fractures were more likely to die of their injuries (p-value 0.020).

Conclusions: Findings of the current study demonstrate that while the presence of an open femur fracture does not correlate with an increase in ISS or increase ICU length of stay it may act as a marker for more serious prognosis in polytrauma patients.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_III | Pages 310 - 310
1 Sep 2005
Peskun C McConnell A Beaton D McKee M Kreder H Stephen D Schemitsch E
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Introduction and Aims: The combination of ipsilateral intertrochanteric and femoral shaft fractures is an uncommon pattern associated with high-energy trauma. This retrospective study used self-report measures to evaluate functional outcome of patients sustaining this fracture pattern and compared two common treatment methods.

Method: Three patient-based outcome measures, the Short Form-36 (SF-36), Short Musculoskeletal Functional Assessment (SMFA), and Lower Extremity Functional Scale (LEFS) were used to evaluate the functional outcome of twenty-one patients (13 male, mean 46.7 +/− 16.5 years) treated with a reconstruction nail (n=11) or with a sliding hip screw and retrograde nail (n=10).

Results: Mechanisms of injury included motor vehicle accidents (66.7%) and falls from height (14.3%). SF-36 physical and mental component scores were less than Canadian norms, with mean values of 35.9 (p=0.0001) and 43.7 (p=0.02), respectively. There was a trend towards better functional outcome in the group treated with the sliding hip screw with retrograde nail despite this group sustaining more severe injuries as measured by ISS (p=0.004), number of days in hospital (p=0.027), and number of days in ICU (p=0.009).

Conclusion: Functional outcome following treatment of ipsilateral intertrochanteric and femoral shaft fractures was reduced compared to Canadian norms. Despite having sustained more severe injuries, the sliding hip screw with retrograde nail group showed a trend towards better outcome as compared to the group treated with the reconstruction nail.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_III | Pages 336 - 336
1 Sep 2005
Droll K Perna P McConnell A Beaton D Schemitsch E McKee M
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Introduction and Aims: Patient-based functional outcome and strength following plate fixation of diaphyseal fractures of the radius and ulna is unknown. Therefore, the purpose of this study was to investigate patient-based functional outcome and objectively measured strength following plate fixation of fractures of both bones of the forearm (BBOF).

Method: Twenty-five subjects (M/F 19/6, mean age 47.6 (range 20–71) treated with plate fixation for fractures of BBOF were clinically and radiographically reviewed. Mean duration of follow-up was 5.7 years (range 2–13.4 years). Post-operative protocol included short-term immobilisation followed by active-assisted ROM and strengthening starting between four and six weeks. All subjects were assessed in person at follow-up with a detailed examination of strength of their injured and non-injured arms. Isometric muscle strength was objectively measured with the Baltimore Therapeutic Equipment work simulator (model WS-20). Standardised anteroposterior and lateral radiographs were made of both forearms.

Results: Strength of elbow flexion (72% of non-injured arm, p< 0.0001), elbow extension (84%, p=0.0004), forearm supination (75%, p=0.005), forearm pronation (69%, p< 0.0001), wrist flexion (81%, p=0.009), wrist extension (62%, p< 0.0001) and grip (70%, p< 0.0001) were all significantly reduced in the injured arm. Mean (+/− SE) DASH and Gartland-Werley scores were 19.5 +/− 4.0 (range 0–61) and 4.04 +/− 0.91 (range 0–15) respectively. Eighty-eight percent (22/25) scored good to excellent on the Gartland-Werley scale. No statistical difference in mean maximal radial bow (MRB) between injured and non-injured arm was found (mean +/− SE, 1.42 +/− 0.07 vs 1.58 +/− 0.05 respectively) or in location of MRB (61% vs 59%).

Conclusion: Restoration of anatomic alignment with stable internal fixation following BBOF fracture results in good to excellent functional outcome. Despite this, significant reduction in strength of the elbow, forearm, wrist and grip should be expected following this injury, and is an area for potential improvement in post-operative care.


Orthopaedic Proceedings
Vol. 87-B, Issue SUPP_III | Pages 307 - 307
1 Sep 2005
Waddell J Schemitsch E McKee M McConnell A James S
Full Access

Introduction and Aims: Open femoral fracture is a serious injury. We have asked the question: do open femur fractures in polytrauma patients correlate with higher injury severity scores, increased length of stay and higher mortality rates than in closed femur fracture polytrauma patients.

Method: We undertook a retrospective review of a prospectively gathered trauma database at a Level 1 trauma centre. We identified multiple-injured patients with femur fractures who presented in a 36-month period. The cases were divided into two groups: open femur fractures (n=33) and closed femur fractures (n=80). Data was collected on demographics, precipitating event, length of stay spent in the ICU, number of associated injuries, ISS, AIS for affected systems, number of femoral surgeries and disposition. Data was analysed using parametric statistical tests with a significance level of 0.05.

Results: Our analysis revealed that on average, patients in the open femur fracture group spent eight + nine days in ICU, sustained four + one associated injuries, underwent two + one femoral surgeries, had an ISS of 29 + 13, and died of their injuries in 30.3% of cases. Patients in the closed femur fracture groups spent eight + nine days in ICU, sustained four + one associated injuries, underwent one + one femoral surgeries, had an ISS of 29 + 14, and died of their injuries in 12.5% of cases. One-way ANOVA showed no statistically significant difference between groups in terms of time spent in ICU, ISS and number of associated injuries. The average number of surgeries was significantly greater in the open femur fracture group (p-value 0.000). A Chi-squared analysis of disposition indicated that patients with femur fractures were more likely to die of their injuries (p-value 0.020).

Conclusions: Findings of the current study demonstrate that while the presence of an open femur fracture does not correlate with an increase in ISS or increase ICU length of stay, it may act as a marker for more serious prognosis in polytrauma patients.