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The Bone & Joint Journal
Vol. 103-B, Issue 2 | Pages 329 - 337
1 Feb 2021
MacDessi SJ Griffiths-Jones W Harris IA Bellemans J Chen DB

Aims

A comprehensive classification for coronal lower limb alignment with predictive capabilities for knee balance would be beneficial in total knee arthroplasty (TKA). This paper describes the Coronal Plane Alignment of the Knee (CPAK) classification and examines its utility in preoperative soft tissue balance prediction, comparing kinematic alignment (KA) to mechanical alignment (MA).

Methods

A radiological analysis of 500 healthy and 500 osteoarthritic (OA) knees was used to assess the applicability of the CPAK classification. CPAK comprises nine phenotypes based on the arithmetic HKA (aHKA) that estimates constitutional limb alignment and joint line obliquity (JLO). Intraoperative balance was compared within each phenotype in a cohort of 138 computer-assisted TKAs randomized to KA or MA. Primary outcomes included descriptive analyses of healthy and OA groups per CPAK type, and comparison of balance at 10° of flexion within each type. Secondary outcomes assessed balance at 45° and 90° and bone recuts required to achieve final knee balance within each CPAK type.


The Bone & Joint Journal
Vol. 102-B, Issue 11 | Pages 1511 - 1518
1 Nov 2020
Banger MS Johnston WD Razii N Doonan J Rowe PJ Jones BG MacLean AD Blyth MJG

Aims

The aim of this study was to compare robotic arm-assisted bi-unicompartmental knee arthroplasty (bi-UKA) with conventional mechanically aligned total knee arthroplasty (TKA) in order to determine the changes in the anatomy of the knee and alignment of the lower limb following surgery.

Methods

An analysis of 38 patients who underwent TKA and 32 who underwent bi-UKA was performed as a secondary study from a prospective, single-centre, randomized controlled trial. CT imaging was used to measure coronal, sagittal, and axial alignment of the knee preoperatively and at three months postoperatively to determine changes in anatomy that had occurred as a result of the surgery. The hip-knee-ankle angle (HKAA) was also measured to identify any differences between the two groups.


Bone & Joint Open
Vol. 1, Issue 7 | Pages 339 - 345
3 Jul 2020
MacDessi SJ Griffiths-Jones W Harris IA Bellemans J Chen DB

Aims

An algorithm to determine the constitutional alignment of the lower limb once arthritic deformity has occurred would be of value when undertaking kinematically aligned total knee arthroplasty (TKA). The purpose of this study was to determine if the arithmetic hip-knee-ankle angle (aHKA) algorithm could estimate the constitutional alignment of the lower limb following development of significant arthritis.

Methods

A matched-pairs radiological study was undertaken comparing the aHKA of an osteoarthritic knee (aHKA-OA) with the mechanical HKA of the contralateral normal knee (mHKA-N). Patients with Grade 3 or 4 Kellgren-Lawrence tibiofemoral osteoarthritis in an arthritic knee undergoing TKA and Grade 0 or 1 osteoarthritis in the contralateral normal knee were included. The aHKA algorithm subtracts the lateral distal femoral angle (LDFA) from the medial proximal tibial angle (MPTA) measured on standing long leg radiographs. The primary outcome was the mean of the paired differences in the aHKA-OA and mHKA-N. Secondary outcomes included comparison of sex-based differences and capacity of the aHKA to determine the constitutional alignment based on degree of deformity.


The Bone & Joint Journal
Vol. 102-B, Issue 1 | Pages 117 - 124
1 Jan 2020
MacDessi SJ Griffiths-Jones W Chen DB Griffiths-Jones S Wood JA Diwan AD Harris IA

Aims

It is unknown whether kinematic alignment (KA) objectively improves knee balance in total knee arthroplasty (TKA), despite this being the biomechanical rationale for its use. This study aimed to determine whether restoring the constitutional alignment using a restrictive KA protocol resulted in better quantitative knee balance than mechanical alignment (MA).

Methods

We conducted a randomized superiority trial comparing patients undergoing TKA assigned to KA within a restrictive safe zone or MA. Optimal knee balance was defined as an intercompartmental pressure difference (ICPD) of 15 psi or less using a pressure sensor. The primary endpoint was the mean intraoperative ICPD at 10° of flexion prior to knee balancing. Secondary outcomes included balance at 45° and 90°, requirements for balancing procedures, and presence of tibiofemoral lift-off.


Orthopaedic Proceedings
Vol. 100-B, Issue SUPP_12 | Pages 16 - 16
1 Oct 2018
Sculco TP Jones C Selemon N Miller A Henry M Sculco PK Nocon AA
Full Access

Introduction

Periprosthetic joinTt infection (PJI) remains an uncommon, yet devastating complication of total hip arthroplasty (THA) and total knee arthroplasty (TKA). Debridement with antibiotics and implant retention (DAIR) provides an alternative to staged revision. Chronic infection is considered to be a contraindication to DAIR, however, outcomes stratified by chronicity have not been documented.

Methods

We performed a retrospective review of all DAIR cases performed at our institution between 2008–2015. Timeframe to treatment was categorized as acute (< 6 weeks since surgery), chronic (>6 weeks since surgery) or acute hematogenous (previously well-functioning prosthesis). Treatment failure was defined as reoperation during the first 90-days following DAIR. Univariate analysis (Mann-Whitney U and Chi-square; p<0.05) and generalized estimating equations (GEE) were used with multiple comparison adjustment by Tukey-Kramer method (α = 0.05).


The Bone & Joint Journal
Vol. 98-B, Issue 10_Supple_B | Pages 22 - 27
1 Oct 2016
Bottomley N Jones LD Rout R Alvand A Rombach I Evans T Jackson WFM Beard DJ Price AJ

Aims

The aim of this to study was to compare the previously unreported long-term survival outcome of the Oxford medial unicompartmental knee arthroplasty (UKA) performed by trainee surgeons and consultants.

Patients and Methods

We therefore identified a previously unreported cohort of 1084 knees in 947 patients who had a UKA inserted for anteromedial knee arthritis by consultants and surgeons in training, at a tertiary arthroplasty centre and performed survival analysis on the group with revision as the endpoint.


The Bone & Joint Journal
Vol. 98-B, Issue 10_Supple_B | Pages 16 - 21
1 Oct 2016
Jones GG Kotti M Wiik AV Collins R Brevadt MJ Strachan RK Cobb JP

Aims

To compare the gait of unicompartmental knee arthroplasty (UKA) and total knee arthroplasty (TKA) patients with healthy controls, using a machine-learning approach.

Patients and Methods

145 participants (121 healthy controls, 12 patients with cruciate-retaining TKA, and 12 with mobile-bearing medial UKA) were recruited. The TKA and UKA patients were a minimum of 12 months post-operative, and matched for pattern and severity of arthrosis, age, and body mass index.

Participants walked on an instrumented treadmill until their maximum walking speed was reached. Temporospatial gait parameters, and vertical ground reaction force data, were captured at each speed. Oxford knee scores (OKS) were also collected. An ensemble of trees algorithm was used to analyse the data: 27 gait variables were used to train classification trees for each speed, with a binary output prediction of whether these variables were derived from a UKA or TKA patient. Healthy control gait data was then tested by the decision trees at each speed and a final classification (UKA or TKA) reached for each subject in a majority voting manner over all gait cycles and speeds. Top walking speed was also recorded.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIX | Pages 61 - 61
1 Jul 2012
Chambers S Jones M Michla Y Kader D
Full Access

The purpose of this study was to determine the accuracy of MRI scan for the detection of meniscal pathology in our unit. There are published data which show that both sensitivity and specificity can approach 90% when compared to arthroscopic findings.

We retrospectively analysed a single surgeon series of 240 scopes for all indications The arthroscopic reports included an outline diagram of the meniscus upon which the surgeon recorded operative findings. 112 of these patients had also had recent MRI.

We looked at whether the MRI report showed a tear, and this was graded Y/N. The arthroscopic report was graded for tear: Y/N. 66 patients had a positive scan. 64 of these were found to have a tear at surgery. 37 scans were reported as “no tear”, of which 4 were found to have a tear at surgery. Nine scans were not easy to classify as they were descriptive.

In our series of 112 knees, MRI was 90.5% sensitive, 89.5% specific and 90.1% accurate.

When a definite diagnosis of “tear”, or “no tear” was made at scan, there were two false positives and four false negatives. False positives may be unnecessarily exposed to the risks of surgery. Patients with negative scans had a mean delay to surgery of 33 weeks compared to 18 weeks for patients with positive scans. False negatives may wait longer for their surgery. Two of the false negative scans clearly showed meniscus tears which were missed by the reporting radiographer. In our series the scan itself was more accurate than the reporting. It is important to have an experienced musculoskeletal radiologist to minimise the number of missed tears. It is also important for surgeon to check the scan as well as the report.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIX | Pages 44 - 44
1 Jul 2012
Blyth M Jones B Smith J Rowe P
Full Access

Recent advancements in optical navigated TKA have shown improved overall limb alignment, implant placement and reduced outliers compared to conventional TKA. This study represents the first RCT comparing EM navigation and conventional TKA. 3D alignment was analysed from CT scans. Clinical scores (Oxford Knee Score (OKS) and American Knee Society Score (AKSS)) were recorded at pre-op, 3 and 12 months post-op. Data presented includes 180 patients (n=90 per group) at 3 months and 140 (n=70 per group) at 12 months.

The groups had similar mean mechanical axis alignments (EM 0.31° valgus; conventional 0.15° valgus). Mechanical axis alignment however was improved in the EM group with 92% within +/−3° of neutral compared to 84% of the conventional group (p=0.90). The EM group showed improved coronal and sagittal femoral alignment and improved coronal, sagittal and rotational tibial alignment, which was significant for sagittal femoral alignment (p=0.04). The OKS and AKSS scores were significantly better for the EM group at 3 months post-op (OKS p=0.02, AKSS p=0.04), but there was no difference between groups at 12 months. The mean pre-op range of motion (ROM) for both groups was 105°. This decreased at 3 months to 102° in the EM group and 99° in the conventional group, but there was a significant improvement by 12 months: EM=113° (p=0.012) and conventional=112° (p=0.026). ROM was statistically similar between groups at all assessment phases.

Knee alignment was better restored following EM navigated TKA relative to conventional TKA, but the difference was not significant. The EM group showed greater clinical improvements at early follow-up; however this difference was not sustained at 12 months. ROM was seen to decrease at 3 months but then significantly improve by 12 month post-op. Proving cost-effectiveness for navigation systems in TKA remains a challenge.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIX | Pages 2 - 2
1 Jul 2012
Jones MA Newell C Howard PW
Full Access

Purpose

To establish the reliability of reporting and recording revision hip and knee arthroplasties by comparing data in the National Joint Registry (NJR), Hospital Episode Statistics (HES) and our local theatre records.

Methods

The paper theatre registers for all orthopaedic theatres in the Royal Derby Hospitals NHS Trust were examined for details of revision hip and knee replacements carried out in 2007 and 2008. This was then cross-checked and merged with the local electronic theatre data to obtain a definitive local record of all revision hip and knee arthroplasties. Data for the same period was requested from the NJR and HES and these data were checked against our definitive local record for discrepancies. The HES codes used were the same codes used to compile the recent NJR annual reports.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIX | Pages 85 - 85
1 Jul 2012
Jain R Majid I Liu A Jones R Johnson D
Full Access

Aim

To determine the tensile forces across the knee extensor mechanism during walking, in simulated conditions of treatment.

Methods

Gait analysis of six normal subjects was performed, with full weight bearing unilateral immobilisation of the knee during walking. Measurements were taken without then with a brace, unlocked then locked at 0°, 0-10°, 0-20° and 0-30° of flexion. Mean and maximum knee flexion angles were measured, followed by calculation of the mean and maximum forces across the extensor mechanism during loading, supporting and propulsion phases of gait.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_XXIX | Pages 56 - 56
1 Jul 2012
Azam A Agarwal S Morgan-Jones R
Full Access

Purpose of the study

This study was undertaken to evaluate the early results of a new implant system - the metaphyseal sleeve - in revision total knee replacement. The femoral and tibial metaphyseal sleeves are a modular option designed to deal with metaphyseal bone loss and achieve cementless fixation over a relatively wide area in the metaphysis.

Methods

Over three years, femoral and/or tibial metaphyseal sleeves were implanted in 104 knees in 103 patients (54 male and 49 female). The clinical notes and radiographs of these patients were reviewed retrospectively. Thirty one patients had revision for infection, 42 for aseptic loosening, and 31 for instability, pain or stiffness. Eighty nine knees were revised as a single stage and 15 were done as two stage procedure. Minimum follow up is 12 months (average 18.5 months).


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IX | Pages 59 - 59
1 Mar 2012
Gallacher P Gilbert R Carrothers A Kanes G Roberts S Rees D Jones R Hunt A
Full Access

Hypothesis

Avascular meniscal tears can be repaired with good clinical outcomes.

Background

The mechanical disadvantage and detrimental effect to articular cartilage following meniscectomy has been well documented in the literature. Meniscal repair in the avascular (white on white zone) is controversial and would be deemed inappropriate by many.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IX | Pages 29 - 29
1 Mar 2012
White SH Roberts SJ Jones PW
Full Access

This is a study of the quality of outcome of the first 100 patients who received the Twin Peg Oxford Partial knee replacement; which has been designed with a 15 degree extra surface for contact in deep flexion, and two pins for more secure fixation. We measured the outcome in patients with anteromedial osteoarthritis at 2 years after implantation using patient perception outcome measures: the OKS (Oxford Knee Score) and a patient satisfaction questionnaire. We also measured range of motion, the AKS (American Knee Society Score-Objective), the AFS (American Knee Society Score-Functional), and carried out a radiological assessment.

The results showed a mean OKS of 41, a mean AKS of 93, a mean AFS of 84, a mean range of motion of 130 degrees and a 97% satisfaction rate. Results were significantly better in male patients. There were no deaths, infections, dislocations, fractures or revisions. There were no radiolucent lines of 2 mms or more at the femoral bone-cement interfaces.

The introduction of this new version of the Oxford knee shows excellent clinical and radiological results which are at least as good as those seen with the Phase 3 Oxford Partial knee replacement. Small adjustments were made to the minimally invasive approach: a reduced invasive incision for ease of implantation. For those surgeons who are concerned over the risks of femoral loosening with the Phase 3 implant, or desire an improved surface area of contact at high angles of flexion, this Twin Peg Oxford Partial knee replacement offers an excellent alternative.


Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_IX | Pages 78 - 78
1 Mar 2012
Jeavons RP Dowen D Jones R O'Brien S
Full Access

Simultaneous bilateral Total Knee Arthroplasty (TKA) has been reported to bring greater patient satisfaction, reduce in-patient stay and recovery, with similar outcomes to single sided or staged TKA, but higher complication rates. No validated selection criteria exist.

We report the results of a single surgeon's experience of simultaneous bilateral TKA, using set guidelines for patient selection.

A prospectively maintained database of all simultaneous bilateral TKA performed between 2002 and 2008 was retrospectively analysed, supplemented by case-note review. Outcome measures included length of stay, blood loss and transfusion rates, complications and functionality and validated outcome scores.

40 patients were included, 23 male and 17 female, all with osteoarthritis. Mean age was male 64.9 and female 61.3 years. Mean ASA grade was 1.8. All fitted selection criteria. Mean tourniquet time was right 79.1 minutes and left 83.6 minutes. Preoperative mean haemoglobin level was 141.8 g/dl and mean post operative level of 87.3 g/dl. 13 patients received purely autologous blood transfusion, 16 patients purely allogenic and 6 patients received both. There was 1 intraoperative complication (Medial collateral injury), 3 minor post operative complications which recovered prior to discharge. There were no thromboembolic events or deaths. Mean follow-up was 32.7 months (range 3-79 months). Mean in-patient stay was 7.5 days. Mean range of movement at most recent follow up was right 1.0 to 119.1 degrees flexion and left 1.0 to 120.8 degrees flexion. Mean Knee Society Scores pre- versus post-operatively were: 67 knee/62 function versus 90 knee/82 function. Oxford Knee Scores, Pre- versus post-operatively were: 43 versus 35 (Scoring 0-60, lowest best outcome).

We demonstrate that with appropriate selection criteria, simultaneous bilateral TKA is safe and successful, giving excellent functional outcomes.