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General Orthopaedics

COMPARATIVE STUDY IN COAGULATION TEST BETWEEN RIVAROXABAN (XARELTO®) AND ENOXAPARIN (CLEXANE®)

The International Society for Technology in Arthroplasty (ISTA), 29th Annual Congress, October 2016. PART 3.



Abstract

Introduction

Embolism in total arthroplasty or hip fractures, coagulation disorders, such as a variety of ways for the prevention of complications of anticoagulation therapy with medication is being done well. The purpose of this study, a representative of the anticoagulation therapy with enoxaparin and drug rivaroxaban of coagulation tests performed in patients between the two groups was to determine whether statistically significant differences.

Methods

47 patients who underwent arthroscopic surgery were randomly divided into two groups to rivaroxaban and enoxaparin group, and we performed coagulation tests before and 5 days after arthroscopic surgery to two drugs groups in order to investigate about the difference in clotting capacity.

Results

Preoperative coagulation tests coagulation tests before the item was not significantly different between the two groups. (p=0.584) 5 days after surgery, the coagulation tests coagulation tests performed on all items, rivaroxaban showed an increase in the anticoagulation activity Between the two groups showed statistically significant difference (p=0.001),

Discussion and Conclusion

Our results indicate that orthopaedic surgery can induce a lot of bleeding will be careful for use of rivaroxaban.

Rivaroxaban(Xarelto®) showed more bleeding tendency than Enoxaparin(Clexane®). So we should take more attentions in postoperative care after Total Joint Arthroplasty


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