Abstract
Introduction
Successful designs of total hip replacement need to be robust to surgery-related variability. Until recently, only simple parametric studies have explored the influence of surgical variability [1]. This study presents a systematic method for quantifying the effect of variability in positioning on the primary stability of femoral stems using finite element (FE) models.
Methods
Patient specific finite element models were generated of two femurs, one male and one female. An automated algorithm positioned and sized a Corail stem (DePuy Synthes, Warsaw) into each of the femurs to achieve maximum fill of the medullary canal without breaching into the cortical bone boundaries.. Peak joint contact and muscle forces associated with level gait were applied[2] and scaled to the body mass of each subject, whilst the distal femur was rigidly constrained. The space prone to surgical variation was defined by the “gap” between the stem and the inner boundary of the cortical bone. The anterior/posterior and the varus/valgus alignment of the stem within this “gap” was controlled by varying the location of the points defining the shaft axis. The points were taken at 20% and 80% of the stem length (Figure 1). The anteversion angle as well as the vertical and the medial position of the stem were controlled by changing the location of the head centre within the femoral head radius. The location of these points was varied using Latin Hypercube sampling to generate 200 models per femur, each with a unique stem position. The risk of failure was evaluated based on stem micromotion, equivalent strains, and percentage of the bone-prosthesis contact area experiencing more than 7000 µstrains [3].
Results
The range of positions covered in this study adhered to the anatomy of the subjects (Table 1) and none of the stem positions breached into the cortical bone of the femur. The 90th percentile peri-prosthetic strains were between 1770 – 4792 µstrains for the male subject, and 2710 – 11260µstrains for the female subject. The 90th percentile micromotion was between (15.6 – 47) µm for the male subject, and (42.4 – 102.4) µm for the female subject. The percentage of the contact area experiencing more than 7000 µstrains was between (0% – 0.33%) for the male subject, and (0% – 12%) for the female subject.
Discussion
A systematic method for studying the effect of surgical-related variation on primary stability was presented its applicability demonstrated on two femurs. The study found that variation in stem position may result in large variation (up to 1.5 times the baseline position) in strains and micromotions. The magnitude Up to three times the magnitudes for the ideal stem position. This method can be applied to larger samples to understand the influence of different alignment parameters on the primary stability of femoral stems.
