Abstract
Biological fixation of arthroplasty devices through osseointegration via ingrowth or ongrowth can be achieved with a numerous surface treatments and technologies. Surface roughness and topography have evolved to include sintered bead, calcium phosphate coatings and more recently additive manufacturing techniques. Regardless of the technique employed, the clinical goal has always been directed at improving osseointegration and achieve rapid, stable and long-term implant fixation without compromising the mechanical properties of the device.
Pre-clinical models provide insight into the in-vivo efficacy. The in vivo results of a wide range of technologies over the past 20 years have been examined by our laboratory using an adult ovine cortical and cancellous implantation model. This paper will present a twenty year experience of pre-clinical evaluation of bone ingrowth and ongrowth surfaces used for arthroplasty device fixation. The endpoints as well as understanding of the dynamic nature of the bone-implant interface continues to evolve as advanced manufacturing moves forward and the demands on the interface due to patient and surgeon expectations increase.
