Abstract
The prevalence of Staphylococcus infections do not decrease despite the preventive measures. The methicillin-resistant staphylococcus aureus (MRSA) has become a major nosocomial pathogen in community hospitals and responsible 60% of staph infections.
Through this study we try to study the epidemiology of methicillin-resistant Staphylococcus in the bone and joint infections.
We report a 2-year study retrospectipevelly about 25 cases of bone and joint infection staphilococcus methicillin-resistant. All patients underwent clinical examination, an inflammatory balance and surgical treatment with sampling and bacteriological study of the removal liquid and regular monitoring in all patients.
The mean age was 5 years and a half. The sexe ratio was 1.2. mean follow-up of 3 months. One patient had dificit G6PD.
The mostaffected area was the capital in 64% of cases.
The most common location was at the knee in 32%. The most frequent diagnosis was arthritis followed by osteomyelitis.
The antibiotics of the first intention was based on amoxicillin and clavulanic acid associated with an aminoglycoside.
It was effective in 75%, and modified according to the results of susceptibility testing in 10 cases.
The average duration of antibiotic therapy in IV was ten days.
The duration of treatment by oral route relay varies from 10 to 21 days. The apyrexia on day 1 postoperatively was obtained in 73%.
The screening of patients at risk of carrying MRSA and isolation should help keep to a minimum cross transmission of infections and the number of non-colonized patients. Place of antibiotic therapy is preponderant and meets pharmacodynamic and pharmacokinetic criteria that must be followed in order to optimize medical treatment.
