Abstract
The process by which pathologic scar tissue forms after TKA and restricts functional range of motion is relatively poorly understood. Arthrofibrosis may develop in patients who have normal intra-operative range of motion (ROM). However, passive flexion, extension, or both can become restricted and painful, sometimes several weeks after surgery following an early post-operative period of normal motion. The response to both nonsurgical and surgical treatment is often unsatisfactory. Arthrofibrotic scar contains dense fibrous tissue with abundant fibroblasts. Heterotopic bone is frequently found in patients with arthrofibrosis.
Stiffness may result from inadequate postsurgical pain management or rehabilitation or from a biologic process that causes rapid proliferation of scar tissue. Genetic factors also may play a role, although it is difficult to predict which patients are at increased risk for arthrofibrosis after TKA. Surgical technique also can contribute; oversizing the femoral component, overstuffing the patella, or rotational malalignment can play a role.
Manipulation can be helpful, particularly during the first three months after surgery. However, maintaining motion long term also requires an effective pain management and physical therapy program after manipulation. Arthroscopy may also have a role to remove scar tissue in the suprapatellar pouch and medial and lateral gutters usually between six months and one year after TKA. After one year following TKA, open surgical release or revision surgery is the most effective method to increase motion. However, only modest gains are likely to be achieved and pain may not be improved.
