Abstract
Purpose
The importance of femoral head-neck morphology in the development of early hip osteoarthritis is recognized in femeroacetabular impingement (FAI), however no studies have examined FAI morphology in the developing hip, i.e. pre-closure of the proximal femoral physis. We developed a pilot project to study prevalence of CAM-type FAI hip morphology in both the pre- and post-closure proximal femoral physes of asymptomatic children using MR-imaging. We also examined biologic markers possibly related to FAI etiology, including Vitamin D metabolites, BMI, family history, and activity levels.
Method
Recruitment included volunteers with asymptomatic lower extremities, and either pre- or post-closure of the proximal femoral physis. Males were 10–12 years (pre-closure) or 15–18 years (post-closure); females were 8–10 years or 14 18 years. Phlebotomy and urine sampling were used to assess metabolic markers. MRI of bilateral hips and a clinical exam including hip impingement tests were conducted. MR imaging assessment was independent and blinded and recorded using established parameters including alpha angles measured at both the 3:00 (anterior head-neck junction) and 1:30 (antero-superior head-neck junction) radial image positions.
Results
Fifty-two volunteers were recruited (32 boys, 20 girls), of whom 44 had bilateral hips imaged (88 hips). Radiographic analysis showed no CAM-type morphology in pre-closure hips and 14% in post-closure hips, using established criteria (alpha > 50.5). The difference between alpha angle measurements at 3:00 and 1:30 positions (5.16) appears significant in developing hips.
Conclusion
Results confirm our ability to recruit a cohort of asymptomatic children for the proposed methodology. Collected data found FAI in 14% of the closed-physes group and 0 % in the open physes group suggesting possible physeal closure importance. The difference between 3:00 and 1:30 alpha angle measurements was significantly less than in published adult figures, further suggesting a developmental role in CAM-Type FAI. This is the first published attempt to assess CAM-type FAI morphology in the developing hip. Preliminary data suggests the period just prior to physeal closure may have significant etiological implications. New parameters for imaging angles are suggested. The study results will guide future cohort study designs.
