Abstract
Introduction
Circular frames in the lower limbs have been removed by Specialist nurses in our clinics for the past 20 years using Entonox. This standard of care has helped reduce the burden of health care cost by avoiding removal of frames in theatres. We have recently started using Penthrox and present our encouraging initial data suggestive of superior efficacy when compared to Entonox.
Materials and Methods
We included in this study the last ten patients on whom Entonox was used during frame removal and the first ten patients on whom Penthrox was used. Visual analogue pain scale was used to quantify pain at the beginning, middle and at the end of frame removal in both groups. The data was found to be normally distributed and Unpaired T test was used to analyse it. Confidence interval of 95% and p-value 0.05 deemed significant.
Results
At the beginning of frame removal the Entonox group had a mean VAS score of 5.3 and Penthrox group had 3 (p-value 0.1194). During the middle of frame removal the Entonox group had a mean VAS score of 7.3 and Penthrox group had 4.5 (p-value 0.0379, statistically significant). At the end of frame removal the Entonox group had a mean VAS score of 4.2 and Penthrox group had 2.3 (p-value 0.1734). Penthrox group showed a statistically significant improvement in the mean VAS pain score when assessed in the middle of frame removal. The mean VAS score of both groups were not statistically significant at the beginning and end of frame removal.
Conclusions
We found Penthrox to offer better pain relief when compared to Entonox during circular frame removal. This will encourage more patients to choose the option of frame removal in the clinic thereby reducing health care cost to the NHS. This pilot study will be followed by a multicentre comparative study where Entonox is in use in comparison to patients at Salford where the practice has shifted to Penthrox
