198. CHROMIUM, COBALT AND TITANIUM ASSAY AFTER IMPLANTATION OF A METAL-ON-METAL CEMENTED BEARING WITH A METAL MULLER INLAY

Abstract

Purpose of the study: For young active patients, implantation of metal backed socket with a metal-on-metal bearing is an attractive tribological alternative when a standard prosthesis cannot be implanted. Metal ion assays have not been reported in this type of population. The purpose of this work was to present the clinical, radiographic and metal ion results.

Material and methods: Between 1998 and 2003 23 total hip arthroplasties (THA) (six primary and 17 revision) were implanted with a cemented Metasul™ bearing in a Muller inlay. Mean follow-up was 6.1 years (5–10). None of the patients was lost to follow-up. The Harris and PMA scores were noted as were signs of implant loosening or migration. Metal ions were assayed in total blood (Cr and Co) by mass spectrometry and atomic emission spectrometry (Ti).

Results: At follow-up, the mean Harris and PMA scores were significantly increased, from 62.2 to 95.2 (p = 0.01) and from 12.9 to 17.4 (p = 0.02) respectively. No revisions were required for aseptic loosening or failure of fixation. The radiographs did not reveal any signs of osteolysis or lucency. The mean levels of Cr, Co and Ti were 1.85μg/l (0.8–3.2). 1.24μg/l (0.5–1.86) and 9.62μg/l (5–18) respectively. Ti > 10μg/l was noted in six patients; Ti > 10 μg/l and Cr > 2μg/l in five patients. There was no correlation of metal ion levels with size of the implants, activity level, gender, clinical scores or cup inclination.

Discussion: The mean Co and Cr levels observed in this series were similar to those reported in the literature for standard THA (cementless press fit cups). Ti levels have only been reported in rare studies so that comparison with other series is hazardous. The Ti level observed here appeared to depend on the femoral stem resurfacing (in our series, the porous surface of the stem was coated with a Ti-6Al-7nB alloy).

Conclusion: Cementing the metal-on-metal bearing in the supporting inlay appears to be a reliable and attractive technique for this young and active population. Levels of Cr and Co in blood were the same as reported for standard implants. These levels of metal ions should be followed to confirm the long-term results.