Abstract
Background – Limb salvage surgeries for soft tissue sarcomas (STS) leads to significant amount of morbidity and fear psychosis among the affected individual. We looked into the potential complications and its implications.
Patients & Methods – Retrospective review of 96 patients over a period of 5 years from 1999 to 2004 with a minimum follow up of 8 months. Complete data of every patient was reviewed with particular emphasis on post op complications.
Results – 72 patients had STS in their lower limbs while the rest had in the upper limbs. 53 tumours were either at the level of knee or above the knee while 19 were found below the knee. The anterior compartment of the thigh was the most common site (13) with Vastus Lateralis being the commonly involved muscle. Liposarcoma was the commonest tumour (22) followed by Leiomyosarcoma (19), Fibro sarcoma (14), Synovial Sarcoma (12), Rhabdomyosarcoma (10), Histiocytoma (9) and other rare sarcomas. 61 patients had wide local excision, 17 had radical excision and 12 had marginal excision. 6 patients had palliative treatment only due to extensive metastasis (mets). 38 patients had post op radiotherapy. The average interval between presentation and definitive treatment was 28 days. 22 of the 71 patients (31 %) with no mets pre op. developed mets during follow up. The commonest problem in the post op period is inadequate skin cover which required skin grafting in 17 cases and flap cover in 3. Three of the skin grafts got necrosed due to radiotherapy. Local recurrence was the next most common complication (12 patients) along with equal number of patients with lymphaedema. Seroma/Haematoma was noted in 8 patients but none required drainage. There were 7 cases of superficial infection and one deep infection. Fixed Flexion Deformity at knee of > 10 0 was noted in 5 cases. Intractable neurological pain was noted in 3 cases involving the upper limb and one involving the lower limb. 3 developed skin rashes after radiotherapy. 2 had ulnar nerve palsy and one had foot drop. DVT occurred in 3 patients. Stump neuroma created problems in 2 cases and 2 patients ended up with below knee amputation. Another notable feature was the fear psychosis among the patients about benign swellings that were present in other parts of their body either before or after surgery which resulted in 11 surgeries but none proved to be malignant. As on 31-3-2005, 39 were dead and the rest were alive. The average life span of the patients who died from the time of confirmed diagnosis was 23 months.
Discussion – There is a plethora of complications that can occur following extensive resection of huge tumours in the extremities. This may involve sacrificing neuro-vascular structures to achieve adequate clearance. In spite of this, there is evidence of frequent local recurrences and distant metastatic spread. There is still some lack of awareness among the public about innocuous looking swellings and they present late with distant metastasis when the prognosis becomes poor.
Conclusion –
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Significant complications can occur after sarcoma surgeries.
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Patient should be adequately informed and educated about the complications
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Surgeon should properly plan his surgery liaising with other specialities
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Radical excision offers no significant advantage over wide local excision followed by radiotherapy.
Correspondence should be addressed to BOOS at the Royal College of Surgeons, 35 - 43 Lincoln’s Inn Fields, London WC2A 3PN
