Abstract
Purpose of the study: Autologous chondrocyte transplantation has become in the last years more and more popular for the treatment of chondral knee lesion. The standard procedure has good result, however important disadvantages represent the difficulty to manage liquid chondrocyte culture solution and the necessity to create the hermatic periosteum suture.The aim of the our study was to investigate the short time results of a matrix-induced chondrocyte transplantation (MACT) for treatment cartilage defects in the knee und to analyse ad- or disadvantages.
Method: Since June 2001 we use for the autologous chondrocyte transplantation (ACT) instead of a periosteum flap the 3-dimensional matrix or resorbarble fleece. 35 patients with defects in cartilage of the knee have been treated so far. Average defect size was 4,8 qcm, all patients had a follow up with clinical investigations and MRI studies. The results were evaluated by different scores.
Results: 33 of 35 patients were after six months satisfied with the operation result or justed it more better. All of the subjective or objektive parameters of the different scores were improved after one year. The clinical outcome was good in the follow-up.
Conclusion: In the follow up the results can be compared with the one found in literature of the standard periost method. The matrix-induced chondrocyte transplantation has the advantage, that no periost flap is needed and that the chondrocyte culture is not liqiud. The first results are promising.
Theses abstracts were prepared by Professor Roger Lemaire. Correspondence should be addressed to EFORT Central Office, Freihofstrasse 22, CH-8700 Küsnacht, Switzerland.
