Abstract
The authors present their experience in bone fusion with blood stem cells, growth factors, AlloMatrix Injectable Putty (Wright Medical Technology, Inc, Arlington, Tenn) and cancellous chips allograft combined in the treatment of compressive vertebral fractures (VCFs).
Eight traumatic vertebral compression fractures at risk of kyphosis were treated by means of transpedicular bone fusion with blood stem cells, growth factors, AlloMatrix Injectable Putty (Wright Medical Technology, Inc, Arlington, Tenn) and cancellous chips allograft. In five patients (group A), mean age 34 years, mean follow-up 13 months, a minimal transpedicular screw fixation was added (two levels). In the other three patients (group B), mean age 26 years, mean follow-up 8 months, the percutaneous fusion was performed by means of vertebroplasty instrumentation. All patients underwent X-ray examination and CT at 45 days, 3 months and 6 months after surgery. In all cases fusion was reached earlier with excellent clinical outcome, especially in group B.
Blood stem cells, growth factors, AlloMatrix Injectable Putty (Wright Medical Technology, Inc, Arlington, Tenn) and cancellous chips allograft combined in the treatment of compressive vertebral fractures seem to be an excellent method even though further studies and more detailed statistical validation are needed.
