O2095 A REVIEW OF 25 SACRAL CHORDOMAS

Abstract

Aim: Chordomas are relatively rare, malignant and strictly found in the midline. This study is to review our experience in the diagnosis, treatment and outcome of sacral chordomas. Method: A retrospective study reviewing 25 sacral chordoma patients treated at the Royal National Orthopaedic Hospital between August 1987 and April 2002, with a minimum follow-up of 6 months. Results: Of the 25 patients, 17 were male and 8 were female. The mean age at diagnosis was 61 years, and the mean duration of symptoms was 2 years. The commonest presenting symptom was lower back pain (20 cases). Three patients had inoperable tumours at the time of referral; the remaining 22 underwent surgical excision. A complete excision (based on microscopic examination) was achieved in11 cases, 2 of whom received adjuvant radiotherapy. Of the11 who had an incomplete excision 8 received adjuvant radiotherapy. Complete excision extended the mean disease free period to2.92 years, compared to 0.67 years following incomplete excision. The disease free period following an incomplete excision was extended from a mean of 0.67 years to 2.82 years with radiotherapy. 10 patients had postoperative neurological complications. Conclusion: We believe that the aim of surgical resection should be a microscopically complete excision margin, having documented an increased time to recurrence in patients in whom this has been achieved, compared to those treated with an incomplete excision. Radiation therapy should be given after an incomplete excision as we have shown that it lengthens the disease free interval in these cases.