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O1261 THE USE OF DEMINERALIZED BONE MATRIX IN THE FILLING OF BONE DEFECTS (PRELIMINARY STUDY)



Abstract

Aims: The evaluation of the results becoming from the use of demineralized bone matrix (DBM) in the bone defects. Methods: In the present study the above substance was implanted during the period 2000-2002 (28 months) to 24 patients, 11 males and 13 females average age 39,1 for the males and 60 for the females. As a cause was referred in 12 patients the fall, in 3 patients the car crash, in 5 patients the following the removal of osteosynthesis materials, in 2 patients the bone cysts, in 1 patient fracture of ankle joint following fusion and in 1 patient a pseudarthrosis. The implantation of DBM concerned 8 hips, 4 femurs, 6 knees, 1 humerus, 1 forearm, 1 ankle, 2 metacarpal and 1 phalanx. All the fractures as well the fusion were treated through internal fixation. There was a regular post op follow-up and concerned the clinical and x-ray examination per month until the total incorporation of the graft (12 weeks). Results: In all patients the total incorporation of the DBM was accomplished in a brief period of time, depended on the place of implantation without having local or systemic side effects. We have to remark the early signs of bone shadow around the 3rd week, as well the incorporation of the matrix around the 12th week in the x-ray findings. Conclusions: The use of DBM in bone defects could play an important role to the filling of bone defrects due to fractures or benign cysts as a result of its incorporation and without inducing local or systematic side effects.

Theses abstracts were prepared by Professor Dr. Frantz Langlais. Correspondence should be addressed to him at EFORT Central Office, Freihofstrasse 22, CH-8700 Küsnacht, Switzerland.