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VANCOMYCIN IMPREGNATED ANTIBIOTIC BEADS IN THE MANAGEMENT OF PROSTHETIC JOINT INFECTION AS PART OF A TWO STAGE PROCEDURE



Abstract

The incidence of infection after primary arthroplasty is low. However, with the increasing number of arthroplasties being performed the prevalence of infection is increasing. The pattern of infecting organisms following total joint arthroplasty has changed and gentamicin resistant organisms are becoming increasingly common. Vancomycin added to bone a cement carrier can, with adequate surgical debridement be very effective in the eradication of established resistant infection. We report the results of its use in 33 patients with 26 infected hip and 7 infected knee arthroplasies. 32 patients remain clinically and radiologically free of infection after a mean follow-up of 67 months. There was one recurrence of infection and there were three positive second stage cultures of uncertain significance. Vancomycin is potentially a very useful tool in the management of deep infection following arthroplasty surgery.

The abstracts were prepared by Peter Kay. Correspondence should be addressed to him at Centre for Hip Surgery, Wrightington Hospital, Appley Bridge, Wigan WN6 9EP.