THE PREVENTION OF PROSTHETIC INFECTION USING A CROSS-LINKED ALBUMIN COATING IN A RABBIT MODEL

Y. H. An; J. Bradley; D. L. Powers; R. J. Friedman

doi:10.1302/0301-620X.79B5.0790816

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THE PREVENTION OF PROSTHETIC INFECTION USING A CROSS-LINKED ALBUMIN COATING IN A RABBIT MODEL

Y. H. An
J. Bradley
D. L. Powers
R. J. Friedman

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THE PREVENTION OF PROSTHETIC INFECTION USING A CROSS-LINKED ALBUMIN COATING IN A RABBIT MODEL

An YH, Bradley J, Powers DL, Friedman RJ. THE PREVENTION OF PROSTHETIC INFECTION USING A CROSS-LINKED ALBUMIN COATING IN A RABBIT MODEL. J Bone Joint Surg Br. 1997;79-B(5):816-819. doi:10.1302/0301-620X.79B5.0790816

An, Y. H., et al. “THE PREVENTION OF PROSTHETIC INFECTION USING A CROSS-LINKED ALBUMIN COATING IN A RABBIT MODEL.” The Journal of Bone & Joint Surgery British Volume, vol. 79-B, no. 5, 1997, pp. 816-819., https://doi.org/10.1302/0301-620X.79B5.0790816

An, Y. H., Bradley, J., Powers, D. L., & Friedman, R. J. (1997). THE PREVENTION OF PROSTHETIC INFECTION USING A CROSS-LINKED ALBUMIN COATING IN A RABBIT MODEL. The Journal of Bone & Joint Surgery British Volume, 79-B(5), 816-819. https://doi.org/10.1302/0301-620X.79B5.0790816

An, Y. H., Bradley, J., Powers, D. L. and Friedman, R. J. (1997) “THE PREVENTION OF PROSTHETIC INFECTION USING A CROSS-LINKED ALBUMIN COATING IN A RABBIT MODEL.” The Journal of Bone & Joint Surgery British Volume, 79-B(5), pp. 816-819. Available at: https://doi.org/10.1302/0301-620X.79B5.0790816

An, Y. H., J. Bradley, D. L. Powers, and R. J. Friedman. “THE PREVENTION OF PROSTHETIC INFECTION USING A CROSS-LINKED ALBUMIN COATING IN A RABBIT MODEL.” The Journal of Bone & Joint Surgery British Volume 79-B, no. 5 (1997): 816-819. https://doi.org/10.1302/0301-620X.79B5.0790816

An YH, Bradley J, Powers DL, Friedman RJ. THE PREVENTION OF PROSTHETIC INFECTION USING A CROSS-LINKED ALBUMIN COATING IN A RABBIT MODEL. J Bone Joint Surg Br. 1997 Sep 1;79-B(5):816-819. https://doi.org/10.1302/0301-620X.79B5.0790816

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Abstract

We evaluated the effects of a serum protein coating on prosthetic infection in 29 adult male rabbits divided into three groups: control, albumin-coated and uncoated. We used 34 grit-blasted, commercially pure titanium implants. Eleven were coated with cross-linked albumin. All the implants were exposed to a suspension of Staphylococcus epidermidis before implantation.

Our findings showed that albumin-coated implants had a much lower infection rate (27%) than the uncoated implants (62%). This may be a useful method of reducing the infection of prostheses.

Correspondence should be sent to Professor R. J. Friedman.

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Journal

The Journal of Bone & Joint Surgery British Volume

Volume

79-B No.5 | Pages 816 - 819

Section

Research

Published

01 September 1997

DOI

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Y. H. An

Assistant Professor

Orthopaedic Research Laboratories, Department of Orthopaedic Surgery, Medical University of South Carolina, 171 Ashley Avenue, Charleston, South Carolina 29425-2239, USA.

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J. Bradley

Medical Student

Orthopaedic Research Laboratories, Department of Orthopaedic Surgery, Medical University of South Carolina, 171 Ashley Avenue, Charleston, South Carolina 29425-2239, USA.

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D. L. Powers

Associate Professor of Bioengineering

Clemson University, Clemson, South Carolina, 29634 USA.

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R. J. Friedman

Professor

Orthopaedic Research Laboratories, Department of Orthopaedic Surgery, Medical University of South Carolina, 171 Ashley Avenue, Charleston, South Carolina 29425-2239, USA.

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