We report a 10% failure rate for aseptic loosening and overall revision rate of 15% at 5 years mean follow up in 190 patients using the Cormet 2000 Dual coat ace-tabular component.

Between April 2001 and March 2004, this cup was used in our region by 4 surgeons. It was peripherally expanded and comprised a cobalt chrome shell, plasma sprayed with a further layer of cobalt chrome which was then coated with hydroxyapatite. This backing has since been abandoned in favour of a titanium plasma coat beneath the hydroxyapatite because of a higher than expected incidence of early loosening.

There were 190 cups implanted in 174 patients, 142 with resurfacing heads. The average age was 54 and 99 were male.

Revision for aseptic loosening was required in 20 cups (10%) at a mean interval of 23 months including five within 2 months, Of the early revisions three developed a deep infection. Undiagnosed groin pain in four further patients appeared at revision to arise from an inflamed bursa secondary to impingement of psoas tendon on the rim of the cup. There was one primary infection, one infection following revision of a trochanteric osteotomy and two neck fractures. Persistent unexplained groin pain was seen in three patients who have declined further surgery

Failure of this backing to integrate with bone led to an unacceptably high early loosening rate. Positioning of the larger resurfacing cups is critical to avoid painful irritation of psoas. Early revision carries a high risk of infection.

We have analysed the early functional results in patients who have had the NRG total knee replacement at the Princess Elizabeth Orthopaedic Centre, Exeter. This is a new modern design designed for high function. We analysed a total of 54 knees (47 patients) operated between September 2005 and October 2007. The follow up ranged from 9 to 25 months averaging 16 months. Thirty eight percent of the patients were male and 62% female. The age of the patients ranged from 42 to 90 (average 72).

The Oxford knee score and satisfaction score were documented at 6 weeks, 6 months, I year and 2 years. The range of movement was also noted. Ninety eight patients had the highest satisfaction score of 3 at the one year follow up. The average Oxford knee score pre-operatively was 45 and the average was 30 at 6 weeks and 6 months and 20 at 1 and 2 year follow up. Seventy four percent of the patients had post operative knee flexion of more than 100 degrees. The average post operative value added flexion was 14 degrees.

We conclude the early results of the NRG knee replacement are very encouraging with very good patient satisfaction scores and post operative flexion of the knee.

This is a study of 24 patients (28 Knees) who underwent acute repair for quadriceps and patellar tendon ruptures using Leeds Keio ligament. Four patients had bilateral quadriceps tendon rupture.

The mean age of patients was 57.4 years (range from 20 to 85 years) with mean follow-up of 20 months (range from 2 months to 3 years). Four patients (6 knees) were lost in follow-up. Knee injury and Osteoarthritis and Outcome Score (KOOS) and Tegner Lysholm Knee Score were used to evaluate the outcome. Sixteen patients had scores of 80 and above in both scoring systems. The mean flexion was 125° and extension lag of 6.6°. The knees were not immobilised after surgery and patients were encouraged to fully weight bear.

One patient had patella fracture secondary to fall although technical error played a part in this. Two patients had bilateral ruptures secondary to fall and one patient had ectopic bone formation. There was no wound infection.

This technique permits immediate mobilisation and full weight bearing of the limb. The early results are promising but long term results are yet to be evaluated.

Between January 2003 and December 2004, 14 patients underwent bilateral resurfacing arthroplasty via a Ganz trochanteric osteotomy. This bilateral group was mobilised fully weight-bearing with crutches. During the same period 139 Ganz trochanteric osteotomies were performed for unilateral hip resurfacing. These patients were mobilised with crutches, weight-bearing up to 10 kg on the operated leg.

Nine osteotomies (32%) in the bilateral group subsequently developed a symptomatic non union requiring revision of fixation. This compares with 10 patients (7%) in the unilateral group. Applying the Fisher’s exact test, the difference reached significance (p=0.0004). In 2 patients a second revision was required to achieve union. In 1 patient, revision of trochanteric fixation precipitated a deep infection.

Protected weight-bearing following a Ganz trochanteric osteotomy is important to the success of the procedure. Simultaneous bilateral hip arthroplasty through a Ganz approach should be avoided. If it is undertaken, we recommend that patients should be non weight-bearing for 6 weeks following surgery. Non union following a Ganz trochanteric osteotomy for arthroplasty carries a significant morbidity.

A number of measurements of patella height exist all of which use a position on the tibia as a reference. The Patellotrochlear Index has recently been proposed as a more accurate reflection of the functional height of the patella and described in normal knees.

We aimed to compare patellar height measurements in patients with patellofemoral dysplasia.

In a retrospective analysis of the MRI scans of 33 knees in 29 patients with patellofemoral dysplasia we assessed the inter- and intraobserver reliability of four patellar height measurements: the Patellotrochlear Index (PTI), Insall-Salvati (IS), Blackburne-Peel (BP) and Caton-Deschamps (CD) ratios. We also assessed the correlation between the different measurements in predicting patella alta. Three blinded observers on two separate occasions performed the measurements.

There were 21 females and 8 males with a mean age of 21.4 years (13–33). Statistical analysis revealed good inter-observer reliability for all measurements (0.78 for PTI, 0.78 for IS, 0.73 for BP and 0.77 for CD). Intra-observer reliability was also good (0.80, 0.83, 0.75, 0.78 respectively). When comparing the different measurements for patella alta there was a weak correlation between the PTI and the others. There was a strong correlation between the CD and BP ratios (0.96) and a moderate correlation between IS and CD and IS and BP ratios (0.594 and 0.539 respectively).

All measurements are reproducible. The PTI however suggests patella alta exists in different patients to that suggested by the established measures. We propose the PTI as a more clinically relevant measure.

Orthopaedic surgery accounts for about 10% of red cell transfusions used in hospital. In view of the recognized risks and decreasing availability of donor blood, every effort should be made to minimize inappropriate transfusions.

Methods: Data was collected on the number of patients prescribed blood transfusion after primary total hip and knee replacement at the North Devon District Hospital. It involved 211 patients in 2004, 599 patients in 2005 and 812 patients in ‘06/’07. The effect of withdrawing the use of drains and instigating local infiltration of the wound with diluted adrenaline on transfusion rates was monitored and the results compared against the national average.

Results: The transfusion rates for hip arthroplasty came down from 15.2% in 2004 to 8.8% in 2007 and for knee arthroplasty from 12.2% in 1004 to 5.3% in 2007.

Conclusion: Our current transfusion rates are well below the national average, without the use of cell savers. We wish to discuss the factors which might affect transfusion rates and share our experience after introducing a simple, inexpensive, safe and effective post-operative blood transfusion policy. The respective contributions of drains and infiltration will be emphasized.

Since 2003 we have adopted an aggressive approach to the management of slipped upper femoral epiphysis (SUFE) deformity, an important cause of femoro-acetabular impingement and associated with the development of early adult hip arthritis.

Sixteen patients aged 16.7 years (range 11–20), 13 male, have undergone surgery to manage their SUFE deformity. Nine underwent primary surgery using a Ganz approach (7) or in-situ pinning with femoral neck resection via a Smith-Peterson approach (2). Seven had previously undergone in-situ pinning 26 months earlier (range 4–44 months) of whom two had acetabular chondral flap tears with eburnated bone and six had significant labral degenerative changes associated with calcification or tears. Only one of the nine patients who underwent primary aggressive management of their SUFE, had a labral tear. Four patients underwent mobilisation of the femoral head on its vascular pedicle, followed by anatomical realignment.

At an average follow-up of 22.3 months (range 1–41 months) 15 remained well with excellent function. Leg lengths remained equal in 12, with average shortening of 2 cm in the remaining four. Segmental AVN occurred in the first patient after damage to the vascular pedicle during drilling of the neck; the technique has been modified to prevent this.

Despite having performed over 400 surgical hip dislocations, the authors continue to find the management of this condition challenging; nevertheless, having seen the consequences of femoro-acetabular impingement in these young patients, we believe that aggressive management to correct anatomical alignment is essential for the future well being of the hip.

The demand for primary hip replacements has grown steadily over the past 20 years and continues to do so. The challenge is to deliver a high quality and cost-effective service by developing short-stay pathways to optimise patient care and outcome.

A four-day hip protocol was established, with attention to detail on analgesia, thrombo-prophylaxis, mobilisation and patient motivation. A multi-disciplinary team was trained to deliver the pathway on a designated ward for primary hip replacements with the aim to discharge patients on the third post-operative day (four day stay in total). Before the initiation of this audit our average stay for primary hips was nine days. The national average stay is 10.6 days, with the top 10 trusts averaging 6.7 days.

In the initial three-month trial, 66 hip replacements (39 females and 27 males) done by the hip team at Princess Elizabeth Orthopaedic Centre in Exeter were audited against the four-day hip protocol. Average age was 72.4 years (range 44 – 92 years). Two patients were discharged on the second post-operative day and another 15 patients on the third post-operative day. As a result, we managed to get 25.8% of the patients home within four days. Overall, the average length of stay was only 6.3 days.

In conclusion, while we only achieved our target in 25.8% of patients, the project improved our overall length of stay remarkably. It is clearly evident that a targeted pathway focused to patient care in all aspects using a multi-disciplinary approach can improve the overall service delivery.

Resurfacing hip arthroplasty is a successful option for the treatment of the young and active patient with hip arthritis. However, it is complicated by femoral neck fracture and avascular necrosis, which result from devascularisation during surgery. Devascularisation maybe caused by thermal necrosis. Thermal necrosis of bone has been shown to occur in temperatures of 47°C and above. We investigated the temperatures generated during femoral head preparation to see if the temperatures reached were great enough to induce osteonecrosis.

Method: Eight patients with osteoarthritis underwent standard resurfacing hip arthroplasty through the posterior approach. From the first over-drilling of the femoral heads until the prosthesis was cemented in place the temperatures generated at the bone surface were recorded using an infra-red thermal imaging camera. Images were captured every 4 seconds as the operation was performed with no interference to the surgeon

Results: The maximum temperatures generated occurred during sleeve reaming at 88.4°C. Seven patients had a temperature recorded greater than 47°C. Removing the femoral caput with an oscillating saw had the highest mean temperature 62.2°C, followed by sleeve reaming (mean 48.7°C). Female patients had the lowest temperature rises and patients receiving the larger femoral prosthesis the greatest temperatures at the bone surface.

Conclusions: Heat generated during femoral head preparation exceeded 47°C in all but one case. Osteonecrosis secondary to thermal insult is likely to occur during femoral head preparation. Strategies need to be devised to decrease the temperatures generated during femoral head preparation.

Effective utilisation of blood products is fundamental. The introduction of Maximum Surgical Blood Ordering Schedules (MSBOS) for operations provides guidance for effective cross-matching. A retrospective analysis of blood ordering practices was undertaken to establish an evidence-based MSBOS for revision THR and TKR. The impact of the use of intraoperative cell-salvage devices was also assessed.

Methods: The patient database was searched for cases of revision THR and TKR undertaken over 58 months. These records were then cross-referenced with the transfusion database. The cross-match to transfusion ratios (CTR) and transfusion indexes (TI) were calculated using this data.

The gold standard for the CTR is 2:1 or less. The TI establishes the likelihood of blood being transfused for a certain procedure. If the TI is less than 0.5, then cross-matching blood is considered unnecessary.

Results: For revisions of non-infected THR (n=269), the CTR=2.24 and TI=1.67. In infected cases (n=69), CTR=2.16 and TI=1.68.

In revisions of non-infected TKR (n=95), the CTR=4.33 and TI=0.48. In infected cases (n=54) the CTR=2.16 and TI=1.35.

There was considerable change in the practice of ordering cross-matched blood following the introduction of intraoperative cell-salvage devices (Revision THR: CTR=1.93, TI=0.84; Revision TKR: CTR=1.20, TI=0.16)

Discussion: The analysis confirmed that more blood was requested than was actually required. Overall the results suggest that cross-matching is still necessary for both the non-infected and infected revision THR but the number of units requested could be reduced to 2 units. In revision TKR, transfusions were more likely in infected cases and, a ‘group & save’ may be sufficient for non-infected cases.

The introduction of this MSBOS in conjunction with intraoperative cell-salvage, could promote blood conservation and financial savings.

Our ongoing aim is to assess the clinical outcome of joint replacement surgery; we wish to contrast the functional outcome of primary and revision patients, and examine what factors may influence this.

Method: Patient data was collected prospectively between Jan 1998 and April 2006. The assessment scores include, the Harris Hip Score, Knee Society Score, SF 36 Health Survey and WOMAC. We compare the pain and function parts of the Knee Society Score for Primary and Revision TKR and the Harris Hip Score for Primary and Revision THR.

Results: The Harris Hip Score improves significantly up to one-year post surgery, with the largest increase occurring at three months. Post surgery improvement then plateaus between one and two years and between two and five years. Revision hip replacement patients display a significant improvement in the Harris Hip Score at three months post surgery, but improvement plateaus after this up to two years. These results are presented graphically.

The Knee Society Score in primary total knee replacement patients improves significantly over time up to one-year post surgery for all components of the score, with the largest increase occurring at three months. Post surgery improvement then plateaus between 1 and 2 years. At 5 years post op both the total score and the function score significantly decrease while there is no change in the knee score component. All components of the Knee Society Score measured in revision knee replacement patients significantly improve at three months post surgery, after which time no further significant improvement is noted.

Discussion: Primary THR patients consistently had higher hip scores than revision patients at all time frames, indicating a better outcome for these patients. When stratified for reason for revision we postulate that a number of well functioning patients are significantly worse following revision surgery. This effect is not seen in the revision TKR group. The decrease in Knee Society Score to five years probably reflects the age of the patients at the time of surgery, which is older than hip replacement patients.

Proximal femoral fractures affect around 60 000 patients annually in the UK. A delay in excess of 48 hours from admission to theatre has been shown to have an adverse effect on mortality, morbidity and length of inpatient stay in this patient group (Hollingworth 1993). We set out to identify the causes and effects of any delay to theatre and make suggestions in order to improve the quality and efficiency of our service.

We tracked 224 consecutive patients all admitted with a proximal femoral fracture over an eight month period. We recorded a number of details including whether or not a delay occurred and why, on a session-by-session basis.

Of the 214 patients included, 75.7% were considered fit enough for surgery at admission; 83.2% of these suffered some sort of delay to theatre. Only 5.6% of patients (8 in total) were considered fit enough for surgery at admission, suffered a delay to theatre and subsequently became unfit causing a further delay.

We were reassured to find that our patients are not suffering a longer than average delay to theatre and that those patients who were waiting longer were not becoming ill as a result. We also found that patients admitted on certain days of the week seemed to wait longer, indicating that certain sub-specialty elective lists were taking up theatre time and exacerbating the delay. We have suggested changes to the theatre rota in order to maximise efficiency and aim to repeat this audit to evaluate the effect of these changes.

Dislocation is a major concern following total hip replacement (THR) for fractured neck of femur. The aim of this prospective study was to investigate the use of large diameter femoral head uncemented THR to treat fractured neck of femur, and to demonstrate if the improved stability seen in previous clinical situations with these designs, can be used to benefit this difficult subgroup of patients that are particularly prone to dislocation.

Forty-six consecutive independent, active and mentally alert patients with displaced intracapsular fractured neck of femur underwent large diameter head uncemented THR. The mean age of patients was 72.1 years. The outcome measures used were the dislocation rate, reoperation and revision rate, Oxford hip score (OHS), Euroqol (EQ-5D) and residential status.

Clinical and radiological data were available on all 46 patients. At a mean follow-up of 12.5 months there were no dislocations. The reoperation, revision and infection rate were all 0%. Two patients died (4.3%) from unrelated causes. Mean pre- and postoperative OHS were 12.1 and 17.9 respectively. The mean pre- and postoperative EQ-5D index scores were 0.97 and 0.83 respectively. The mean postoperative walking distance was 2.5 miles and there were no changes in residential status.

This is the first published series utilising a 36-mm diameter metal-on-metal THR for the treatment of fractured neck of femur in mobile, independent patients. We have demonstrated that it affords patients excellent stability with no recorded dislocations.

Open Tibiotalocalcaneal fusion has been shown to be an effective treatment for arthritis and complex foot deformities, but with a high complication rate. We are reporting the results of the first 14 feet undergoing arthroscopic tibiotalocalcaneal arthrodesis.

Methods: Retrospective review identified 13 patients who had 14 combined ankle and subtalar arthrodeses performed arthroscopically, with no bone grafting. The procedure was performed for the treatment of combined ankle and subtalar arthritis or hindfoot deformity. The majority had fixation using 6.5 mm ASNIS screws (Stryker (Kalamazoo, Michigan, USA)) introduced percutaneously, although in one case a hindfoot nail was used. Outcome was assessed by a combination of chart review, clinical examination and questionnaire. Follow up averaged 16 (6 to 33) months.

Results: At follow up average patient satisfaction was 9.7/10. Average time to fusion was 12 (10–20) weeks. The average postoperative American Orthopaedic Foot and Ankle Society (AOFAS) hindfoot score was 67 (41–83). 9 patients had no complications. Postoperative complications were pulmonary embolus, non-union, late stress fracture and infection.

Conclusion: Arthroscopic hindfoot arthrodesis is an effective technique, and allows treatment in patients whose soft tissues would not tolerate an open procedure, where often the only alternative is amputation. Patient satisfaction is high, with a short inpatient stay, but the procedure itself is demanding.

Introduction – Patients who have sustained a fracture of the hip should have their surgical treatment with 48 hours of admission to hospital. A delay results in increased morbidity and mortality.

This elderly cohort of patients often have confounding co-morbidities. A pre-operative echocardiographic assessment to guide the anaesthetic is frequently requested upon clinical grounds. A delay in acquiring the echocardiogram was observed thus delaying surgery. This instigated a change in policy within the department whereby all patients over 70 years old who sustained a hip fracture underwent echocardiographic assessment with 24 hours of admission.

Method: An audit was performed assessing delays in acquiring the echocardiograms and measuring the time taken to perform the operation.

Results: Period 1 – Selective Echo: Mean time to echo 5 days, mean time to theatre 7 days. Period 2 – Unselective Echo: Mean time to echo 1 day, mean time to theatre 2 days.

Conclusion: As a result of the unselective policy to perform echo cardiograms on all patients admitted with a fractured neck hip, the delay to perform surgery has been reduced significantly.

The incidence of degenerative scoliosis in the lumbar spine is not known. In the ageing population deformity may coexist or cause stenosis. MRI gives limited information on this important parameter in the treatment of stenosis. The aim of this study was to highlight the incidence of coronal abnormalities of the lumbar spine dependent on age in a large population of patients.

We reviewed all abdominal radiographs performed in our hospital over ten months. 2276 radiographs were analysed for degenerative lumbar scoliosis and lateral vertebral slips in patients who are ≥ 20 years old. Evidence of osteoarthritis of the spine was also documented. Radiographs were included if the inferior border of T12 to the superior border of S1 was visualised and no previous spinal surgery was evident (metal work).

2233 (98%) radiographs were analysed. 48% of patients were female. The incidence of degenerative lumbar scoliosis, lateral listhesis and osteoarthritis increased with age. Degenerative scoliosis was present in 1.6% of 30–39 year olds increasing every decade to 29.7% of patients 90 years or older. In all age groups curves were more frequent and had greater average Cobb angles in female patients except in the 30–39 year olds - where males equalled females.

Degenerative lumbar scoliosis starts to appear in the third decade of life increasing in frequency every decade thereafter, affecting almost a third of patients in the ninth decade. It is more common in female patients and has a greater magnitude. Deformity may be even greater on standing views and is important to recognise in all patients that are undergoing lumbar spinal decompressive surgery. A failure to do so may lead to inferior results or the need for further surgery.

Patient satisfaction is a driving force behind setting up and developing day case procedures. Ten months ago a service for day surgery SCARF procedures was set up in Torbay day surgery unit.

We analysed patient pre and post operative pain scores and patient satisfaction scores in respect to pain, appearance and overall satisfaction.

A questionnaire was sent to all sixty patients who had undergone a SCARF osteotomy in day surgery. Outcomes assessed were: reason for SCARF osteotomy; adequate preoperative information; pain scores pre and post operatively; satisfaction scores and admission rates.

53 patients responded (88% response rate). 79% of patients had their operation for pain, 19% for appearance and footwear, and 2% for function of their foot. 100% of patients were given adequate information by the surgeon preoperatively and 27% also used other sources for information. 62% of patients scored 6 or more on a linear pain score preoperatively. 85% of patients have a current pain score of 0 or 1. 87% were highly satisfied (scoring 9 or 10 on linear scale) with the outcome regarding their pain, 83% highly satisfied with appearance and 72% highly satisfied with function despite the questionnaire being completed less than one year post surgery. 83% of patients were highly satisfied with the overall procedure and 91% said they would have a SCARF as a day case procedure again. 9 patients were admitted, 3 due to living alone, 3 for wound problems and 3 for post anaesthetic problems including pain, nausea and vomiting.

From these figures we concluded that SCARF osteotomy in day surgery is a successful, feasible and worthwhile undertaking in our unit.

We used the questionnaires and results to further analyse our service and we have made modifications to improve it. We have now put in place a dedicated anaesthetist with an interest in foot and ankle blocks, as well as a comprehensive post operative analgesic regime and a stringent day surgery protocol.

We now run a prospective questionnaire from clinic, including AAOFAS scores, to continue analysis of our service. With these changes in place we would like to see our satisfaction scores rising towards 100%.

The management of closed ankle fractures requiring open reduction and internal fixation is dependent upon soft tissue swelling to determine the timing of the surgery. At Exeter in 2001 one third of all trauma cases were operated on “out of hours”, in 2007 less than ten percent were principally because of the lack of anaesthetic staff. The senior author has developed a technique of percutaneous ankle fixation that may be undertaken at an early stage despite the presence of swelling.

A retrospective study of four years focusing on time to surgery, time to discharge and complications was compared with a cohort selected at random that had undergone open fixation from the same period. Patients undergoing percutaneous fixation were extracted using the Plato database and all patients were included. Admission documentation, operation notes and subsequent clinic letters were used to ascertain the outcomes. Pre and post-operative imaging was evaluated.

Over a four year period two consultants and four specialist registrars performed the technique on a total of 22 patients. The mean time to surgery was 2.04 days for the percutaneous cohort (range 0–5 days) compared with 4.04 for the open cohort (range 1–10). Time to discharge was 4.6 days to 5.8 in favour of percutaneous. No complications were experienced in the percutaneous cohort compared with 6 patients in the open.

Preliminary results demonstrate a reduced waiting time for surgery and a quicker discharge. Percutaneous fixation is an option when swelling precludes open fixation.

A series of 49 pilon fractures in a tertiary referral centre treated definitively with open reduction and internal fixation have been assessed examining the complications associated with such injuries. A retrospective analysis of casenotes, radiographs and computerised tomographs over a seven year period from 1999–2006 was performed.

Infection was the most common post operative problem. There were 7 cases of superficial infection. There was a single case of deep infection requiring intravenous antibiotics and removal of metalwork. Other notable complications were those of secondary osteoarthritis (three cases) and malunion (one case).

The key finding of this paper is the 2% incidence of deep infection following the direct operative approach to these fractures. The traditional operative approach to such injuries (initially advocated by Ruedi and All-gower) consisted of extensive soft tissue dissection to gain access to the distal tibia. Our preferred method is to gain access to via the “direct approach” which involves direct access to the fracture site with minimal disturbance of the soft tissue envelope. We therefore believe open reduction and internal fixation of pilon fractures via the direct approach to be an excellent technique in the treatment of such injuries.

A Ring Fixator (Taylor Spatial Frame (TSF); Smith & Nephew, Memphis, TN), was used in the treatment of 5 patients (ages 11 to 16 years) with proximal tibial growth arrest following trauma. The mean corrections were 14.20 (max 280, min 00) in the saggital plane and 140 (max 380, min 20) in the coronal plane. Leg length discrepancy was also corrected (max 1 cm). The average time in frame was 17.8 weeks, with an average correction time of 29.8 days. Knee Society Clinical Rating System (KSCRS) scores post operatively ranged from 95 to 100. All patients returned to full activity, and would accept the same treatment if offered again.

The circular fixator is an effective, minimally invasive method of treatment for post-traumatic proximal tibial deformity. Patients remain active during treatment encouraging a rapid return to school/work activities.

Objectives: To compare the biomechanical properties of lag screw insertion in a laboratory model. Two blades, the Synthes Dynamic Helical Hip Screw (DHHS) and Proximal Femoral Nail Antirotation (PFNA), and two screws, the Synthes Dynamic Hip Screw (DHS) and Stryker Gamma 3 lag screw, were compared.

Setting: Orthopaedic biomechanics laboratory.

Design: Insertion testing was carried out in high and low density polyurethane foam mounted and attached to a Zwick Roell Amsler Hydrowin.

Outcome Measures: The axial load and torque during insertion of the implants was measured.

Results: The force required to insert the DHHS and PFNA blades was greater than the DHS and Gamma 3 screws into both low and high density foam. The force required to insert the DHHS and PFNA blades into high density foam was greater than low density foam. The torque required to insert the DHHS and PFNA blades into high density foam was less than that to insert the DHS and Gamma 3 screws. The torque required to insert the DHS and Gamma 3 screws into low density foam was less than the DHHS and PFNA blades. The torque during insertion of the DHHS and PFNA blades seemed to be independent of foam density.

Conclusions: The insertional properties of blades are significantly different to screws and this may have clinical importance.

Immobilisation is known to be a risk factor for thromboembolic events and the management of ankle fractures often involves immobilisation of the fracture in a below knee cast. Recent literature has found a 5% rate of subclinical deep vein thrombosis (DVT) and suggested thromboembolic prophylaxis is not required.

This study involved all adult patients with isolated ankle fractures presenting to a district general hospital orthopaedic department over a 6 month period. This included patients undergoing internal fixation as well as non-operative management. A 3 to 7 month follow-up was performed to assess the incidence of clinical DVT or pulmonary embolism (PE) proven using Doppler imaging, venogram, and computed tomography pulmonary angiography. 119 patients met the entry criteria and, of these, 3 patients developed DVT and 2 patients presented with pulmonary embolus. 15 patients in the study were taking aspirin (75–300 mg daily) during their cast immobilisation and 1 patient was taking warfarin. None of these patients developed a thromboembolic complication. 4.8% of patients not taking aspirin or warfarin experienced a thromboembolic complication.

This study demonstrates a relatively high incidence of symptomatic thromboembolism following ankle fractures in the absence of prophylaxis. Previous studies have found aspirin to be an effective method of prophylaxis following hip fractures and total hip arthroplasty. We recommend that thromboembolism prophylaxis is necessary following ankle fractures and suggest that aspirin may be an economical option. Larger studies are needed to evaluate the role of aspirin in this setting.

Chondrosarcoma is treated with respect by oncology surgeons, given that it is relatively resistant to chemotherapy and radiotherapy. The aim was to study the outcomes of surgery for chondrosarcoma and determine the role of initial surgical margins and local recurrence on outcome.

Electronic patient records were retrieved on all patients seen with chondrosarcoma of bone with a minimum of two years follow up. A total of 532 patients were seen with Chondrosarcoma between 1970 and 2006. Patients were excluded if they had initial treatment in another unit (20 patients), a subdiagnosis of dedifferentiated chondrosarcoma (due to very poor prognosis, 43 patients), metastases at presentation (30 patients), if they presented with disseminated metastases prior to local recurrence (12 patients) or were not offered surgery, leaving 402 patients in the study group.

The mean age was 48 years old (range 6–89 years) with the most commonly sites of presentation being in the pelvis in 132 patients (29%), proximal femur in 81 patients (18%), distal femur in 40 patients (9%) and proximal humerus in 40 patients (9%). Grade at presentation was grade 1 in 44%, grade 2 in 44% and grade 3 in 12%. Surgical margins were radical in 3%, wide in 44%, marginal in 29%, planned incisional in 13% and unplanned incisional in 11%. Local recurrence occurred in 87 patients (22%). Local recurrence rates were significantly different for surgical margins on Fisher exact testing (p=0.003), which held true even when stratified by presenting grade of tumour. Surgery for local control was successful in 62% of cases.

Complex relationships exist between surgical margins, local recurrence and survival. Long term survival is possible in 1/3 patients who have local recurrence in intermediate and high grade chondrosarcomas and therefore ever effort should be made to regain local control following local recurrence.

We have compared the cost:benefit ratio of the new type of non invasive extendable prostheses with the old type which required lengthening under general anaesthetic with an invasive procedure.

Over the past four years we have inserted 27 non invasive endoprostheses (cost £14,000). Two have failed to lengthen due to problems with the inbuilt motor. So far there have been no infections, no loosenings and no patient has required revision. The lengthenings are painless and take half an hour. In the past 25 years we inserted 175 extendable endoprostheses (cost £7,000). All lengthenings were performed under a general anaesthetic. The risk of infection was initially 20% at ten years but had decreased to 8%. Pain and stiffness arose in about 10% requiring physiotherapy or occasionally manipulation under anaesthetic.

Assuming the following costs (current NHS cost) are accurate and appropriate, then the non invasive extendable prosthesis becomes cost effective when Cost EPR < Cost old EPR + (Additional risk physio(P) x cost) + (additional cost x number of lengthenings (L)) + (additional cost of revision for infection x risk of infection (R)). 14000 < 7000 + (300 x P) + (1500 x L) + (20000 x R). Assuming a 10% need for physiotherapy, four lengthenings and a 10% risk of infection gives: 14000 < 7000 + (30) +(6000) + (2000) = 15030.

Given the high complication rate of the old type of extendable procedure and assuming there are few if any with the non invasive type, then the non-invasive endoprostheses becomes cost effective if more than three lengthenings are required. They are certainly more popular with parents and children alike!

Objectives:

To determine the diagnostic performance of image-guided percutaneous core needle biopsy (CNB) in patients presenting with pathologic fractures of the appendicular skeleton.

A retrospective audit identified 129 consecutive patients presenting with pathological fractures to a specialist orthopaedic oncology unit over a 9 year period. All patients underwent percutaneous CNB using CT (n=98), fluoroscopy (n=15) or US (n=16) guidance. In all cases MRI or CT was available prior to biopsy to assess the presence and degree of extra-osseous tumour mass. The resulting sample was classified as diagnostic (Group 1) or non-diagnostic (Group 2) on histopathological study. Diagnostic performance was evaluated on the basis of the diagnostic yield and accuracy; these were related to the site of the lesion and presence/absence of extra-osseous mass.

Of 129 biopsies, 99 (77%) were classified as Group 1 and 30 (23%) as Group 2. The commonest sites of pathological fracture without associated soft tissue component and resulting in a non-diagnostic biopsy were the proximal femur and proximal humerus. The average cross-sectional diameter of lesions in Group 1 was 5.7 x 5.9cm. Of the 30 lesions comprising Group 2, no soft tissue component was identified on pre-biopsy cross-sectional imaging in 27 lesions (90%) whereas the remaining 3 (10%) showed a smaller extra-osseous soft tissue component compared to the lesions in Group 1.

Image-guided percutaneous CNB is a reliable method for obtaining a tissue diagnosis in patients presenting with a pathologic fracture of the appendicular skeleton with high accuracy rate. However, those lesions which are purely intra-osseous or have only very small extra-osseous components are likely to be associated with a non-diagnostic biopsy, and should be considered for a primary open procedure.

The purpose of our study was to examine the survival and functional outcome of endoprosthetic replacements for non-oncology limb salvage purposes. Although initially designed for bone tumours, such is the versatility of these implants they can be used to salvage failed joint replacements, peri-prosthetic fractures, failed internal fixation and non-union.

Thirty eight procedures were identified from September 1995 to June 2007 from a prospectively kept database, including 17 distal femoral replacements, 12 proximal femoral replacements, 4 proximal humeral replacements, 2 distal humeral replacements, 2 hemi-pelvic replacements and 1 total femoral replacement. The quality of patients’ mobility was used to assess functional outcome and the survival of the prosthesis was calculated using a Kaplan-Meier survival curve.

The Kaplan-Meier implant survival was 91.3% at 5 years, 68.5% at 10 years and 45.7% at 20 years. The limb salvage survival for all reconstructions was 75% at 10 years.

The best survival was as follows pelvic (n=0/2) and total femoral prostheses where there was no failure in either group (n=0/1). Distal femoral replacements survival was 91% at 5 years, a single humeral prosthesis failed at 11 years post surgery, and proximal femoral replacements had a survival at 87.5% at 5 years. Three implants failed, two as a result of infection and required staged revisions and 1 failed as a result of aseptic loosening. Two patients dislocated their proximal femoral replacements, both were treated successfully by closed reduction.

Endoprosthetic replacement appears to be effective and the medium term survival is encouraging. The aim of a pain free functional limb is achievable with this technique. The complication rates are acceptable considering the salvage nature of these patients. We recommend referral of complex cases to a tertiary centre with expertise in this type of surgery.

The Patient Evaluation Measure (PEM) was designed at the Derby consensus meeting in 1995. It was validated for Carpal Tunnel Syndrome (CTS) in 2005 (Hobby et al) and was preferable to the DASH score for CTS assessment. We aimed to audit CTS treated by surgical decompression in our unit using the PEM, and to compare our results with the published literature.

Thirty consecutive patients undergoing carpal tunnel decompression were questioned about one hand. Patients completed a preoperative PEM and a postoperative PEM at 3 months.

Mean PEM scores improved from 41.3 to 23.9 (P< 0.001). Individual questions showed statistically significant improvements in mean scores: Feeling in the hand, Cold intolerance, Pain, Dexterity, Movement and Hand in general (all P< 0.001): Work (P< 0.005): ADL (P< 0.01): Movements, Grip and Appearance (P< 0.05). Our results are similar to previously published series, both overall, and for individual questions in the PEM.

Results for Carpal Tunnel Decompression in our unit match those of other units. We found the PEM was easy to use; and effective, both in the assessment of patients with CTS, and for outcome measurement following surgical decompression. Our study supports the idea that the PEM could be used widely as an audit tool, to assist Hand Surgeon and/or Hand Surgery Unit Appraisal.

Pelvic reconstruction after tumour resection is challenging. Pelvic replacements are usually custom made at considerable expense and then need very careful positioning at the time of surgery. They have a very high rate of complications with up to 30% risk of infection and 10% dislocation. In 2003 we developed a new type of pelvic replacement which would be simple to make, simple to use and which would hopefully avoid the major complications of previous pelvic replacements whist being versatile to use even when there was very little pelvis remaining. The concept is based on the old design of Ring stemmed hip replacement and has become known as the ice-cream cone prosthesis. It is inserted into the remnant of pelvis or sacrum and is surrounded by bone cement containing antibiotics. One of the main advantages is it’s flexibility, allowing insertion after resection at a variety of levels. It is also suitable for patients with metastatic disease.

We have inserted 12 of these implants in the past 4 years, resolving very difficult reconstruction problems. There was one case that became infected but was cured with washout and antibiotics. In one patient there was excessive leg lengthening resulting in a sciatic and femoral nerve palsy and the prosthesis had to be revised. All patients can walk with one stick or less.

These results are encouraging and suggest that this versatile implant may be the way forward for pelvic reconstruction because of it’s flexibility of use and low complication rate.

We aim to assess the AP distance and teardrop angles in a cohort of normal wrists and to assess their possible use as prognostic indicators in fractures of the distal radius.

Two hundred standardised PA and lateral wrist radiographs from uninjured wrists and 95 patients with fractures of the distal radius were assessed and anatomic parameters measured, including the Teardrop angle and AP distance. Clinical assessment at a mean of 6 years post fracture included an assessment of grip strength and range of motion along with the DASH score.

The mean teardrop angle in 200 normal wrists was 68 degrees (95%CI:67–69 degrees) and did not differ significantly between sexes (p=0.148). The average teardrop angle at presentation in 95 fractures of the distal radius was 47 degrees (95%CI:41–50 degrees), improving significantly to 58 degrees (95%CI:56–61 degrees, p< 0.0001) post-reduction, and this improvement was maintained at 56 degrees (95%CI:54–59 degrees) at union. The final position was significantly better than at presentation (p< 0.0001).

Loss of teardrop angle between the fractured and uninjured wrist was significantly related to reduced grip strength (p=0.04) and worse DASH score (p=0.03). The mean AP distance in 200 normal wrists was 19.6mm (95%CI:19.4–19.9mm) in males and 17.6mm (95%CI:17.2–18.0mm) in females, which is significantly different (p< 0.0001). The mean AP Distance at presentation in 95 fractures of the distal radius was 21.0mm (95%CI:20.4–21.7mm), which improved significantly to 19.6 (95%CI:19.1–20.2mm, p< 0.0001), but subsequently worsened to 20.8mm (95%CI:20.2–20.4mm) at union. This is not significantly better than at presentation (p=0.397). An increase in AP distance in the fractured wrist correlated to loss of range of motion (p< 0.01).

The value of these parameters is that they offer quite detailed assessment of the articular surface of the distal radius in the absence of more detailed imaging. They appear to be of prognostic value.

Osteoarthritis of the first trapeziometacarpal joint (TMCJ) is a disabling disease which reduces the function of the thumb and the hand. Replacement arthroplasty offers a pain free joint as well as mobility, stability and strength.

This study reviews the results of TMCJ arthroplasty using a cemented metal-on-polyethylene implant (Sr TMC, Avanta®). Between 2001–2005 seventy two (n = 72) TMCJ cemented Arthroplasties were performed by a single surgeon. Patients were followed in the clinics for up to six years (median follow up 36 months, range 24–72). Patients were reviewed clinically and radiologically by two independent assessors. For outcome, Sollerman and Quick-DASH scores were used. A Jamar dynamometer was used to assess the grip and pinch strengths. Thirty six patients (46 joints), were seen at final follow up. There were 13 male and 23 female patients. Ten patients had bilateral TMCJ replaced.

Six patients were revised to trapeziectomy and ligament reconstruction with tendon interposition. Four for aseptic loosening and two for traumatic dislocation. Survival after a median follow up of 36 months was 91%. At final follow up mean Quick DASH score was 29.2 and mean Sollerman Score was 77.1. Radiological review of the surviving joints showed lucencies around trapezial component in 8 joints, 4 of which were loose. However these patients had good hand function and grip strength and therefore declined revision surgery. We found that the radiological findings did not correlate with clinical findings. 83% patients were satisfied with the outcome of their treatment.

Early results of Sr-TMC (Avanta) joint replacement are encouraging. We recommend the use of this prosthesis for osteoarthritis of the trapeziometacarpal joint.

Distal radio-ulnar joint (DRUJ) instability is increasingly recognised and can lead to disabling symptoms. Clinical assessment can detect gross instability but is much less reliable for subtle instability. The normal range of DRUJ dorso-palmar translation is not known. Previous biomechanical research has studied DRUJ kinematics using cadaveric models.

We aim to develop a simple, reliable and reproducible tool to measure DRUJ stability and thereby assess the normal range of DRUJ dorso-palmar translation in-vivo.

A test rig was designed and 20 volunteers recruited. The rig held the subject’s elbows at 90° flexion with the distal ulnar secured and the forearm in neutral rotation. Dorso-palmar shear force was applied to the distal radius and displacement measured 3 times on each wrist alternately by the same operator. Volunteers with previous wrist injuries were excluded.

Ten male and 10 female volunteers were recruited. Mean male age 39.1 years (range 22–74). Mean female age 35.8 years (range 25–57). Mean male translation 5.4mm (range 3–9, SD 1.1). Mean female translation 5.5mm (range 4–7, SD 0.9). Mean right sided translation 5.3mm (range 3–8, SD 1.0). Mean left sided translation 5.6mm (range 3–9, SD 1.0). Total mean translation 5.5mm (SD 1.0). Same-sided mean measurements for two subjects taken days apart varied by only 1mm. Intraclass correlation coefficient was 0.93.

The rig is reliable, reproducible and appears to be a valid test of DRUJ translation. The mean DRUJ translation in neutral is 5.5mm. Contralateral sides and between sexes were comparable. We anticipate that the rig will be a research tool to guide clinical practice in DRUJ instability.

We aim to establish the likely functional scores following different types of surgery for bone tumours. All living patients who had undergone treatment for a bone tumour were contacted and invited to complete a TESS self-report questionnaire. The TESS contains 32 items of day-to-day activities which the patient scores themselves against. The final score is a percentage, with 100% being ‘normal’. The project was approved by the local ethical committee.

723 responses were obtained from just over 1000 letters that were sent. Thirty seven sets of data were incomplete leaving a total of 686. There were 369 males and 317 females, with an average age of 49 (range 15 to 93). The mean interval from their initial operation was 12 years (range 1 to 42). 590 of the procedures were in the lower limb and 96 in the upper limb. 126 patients had an amputation and 560 limb salvage (82%).

Mean scores obtained for each procedure were: EPR mid-femur 86%; EPR distal femur 77%; EPR proximal tibia 74%; EPR proximal humerus 71%; EPR proximal femur 71%; Below knee amputation 70%; EPR total femur 63%; Disarticulation of the hip 61%; Above knee amputation 60%; Hindquarter amputation 57%; EPR pelvis 54%.

Younger patients had much better scores (80% for those under 30 vs. 69% for those over 30, p< 0.0001) than those over 30. Additionally, the scores for those that had had an amputation following a EPR procedure were no worse than those who had had an amputation originally. Significantly, EPR proximal tibia was better than AKA (78% vs. 67% p = 0.0003), as was EPR distal femur (80% vs. 67% p < 0.0001).

This data from a large series is helpful in indicating likely outcomes following surgical treatment of sarcomas, both for patients and surgeons.

The aim of this study was two-fold; firstly, to investigate the construct validity of the Disability of the Arm, Shoulder and Hand (DASH) score in patients following injuries to the upper and lower limbs, and to confirm that DASH score does not measure disability solely attributed to the upper limb. Secondly, to create a modified DASH questionnaire (M2 DASH) with fewer questions that can discriminate clearly between disabilities due to problems at the upper limb, and is more specific to the upper limb.

Patients were asked to fill in the DASH questionnaire in a fracture clinic following ethical approval. This included upper limb injuries (79), lower limb injuries (61) and control subjects (52). The median DASH scores for the three groups were 57, 16 and one respectively. The DASH scores varied significantly between the three groups (Kruskal-Wallis: p< 0.001); the scores for the upper limb group were higher than the lower limb group, and the scores for the lower limb group was higher than the control group (Mann-Whitney: p< 0.001). The M2 DASH questionnaire was developed using questions specific to the upper limb and included questions 1–4, 6, 13–17, 21–23 and 26–30. The median M2 DASH scores for the three groups were 50, 7 and 0 respectively. The revised questionnaire score was then calculated for the upper limb group and a correlation study showed good correlation between the two questionnaires.

Our study shows that the original DASH questionnaire is not specific for the upper limb. This has important implications in measuring response in injuries and disease that involve both upper and lower limbs. We have devised a revised questionnaire that we suggest is referred to as M2 DASH questionnaire. The M2 DASH questionnaire has the advantage of being more specific for the upper limb than the DASH questionnaire.

To assess whether by improving patient’s knowledge about the wrist arthroscopy procedure would positively affect the amount of postoperative pain. We tested the effect of a fact sheet that contained detailed information about the procedure on the outcome of such a surgery.

Fifty-five patients undergoing diagnostic wrist arthroscopy were randomly allocated into 2 groups. Group 1 included 28 patients to whom an explanatory form named fact sheet was provided prior to the procedure. 27 patients in the second group did not have the fact sheet. However both groups had the usual preoperative verbal instructions during consenting and all patients had Visual analogue scale pain assessment before surgery. Pain scores were recorded over a 10 day period postoperatively, the end point being the day on which the patient returned to the preoperative pain status.

There were 34 females and 21 males with 47 right and eight left wrists but all were the dominant side. The mean age of the patients was 35 years (range of 16 to 54 years).

In the first 48 hours all patients had flare up of pain in their wrists but by day five, 75% of patients who had the fact sheet, recovered to their preoperative pain status whereas only 22% of patients in the control group had done so. Furthermore, Patients in group 1 resumed their routine daily activities on average three days earlier (day seven) when compared to the control group in whom this return was not complete up to day 10.

Supplying a fact sheet prior to wrist arthroscopy has a positive influence in terms of decreasing the preoperative pain score and reducing the time patients required off work. Given the clear benefits demonstrated by this simple manoeuvre, it is now our practice to provide such a fact sheet to all patients.

Saggital plane deformities are difficult to treat and pose major challenge to orthopaedic surgeons and we are presenting short series of patients who have undergone the deformity correction with ring fixator.

Sixteen deformities in 15 patients were corrected during 1996 to 2004. The aetiology was congenital pterigium five cases, post traumatic seven cases, one each of polio, septic knee and post osteomyelitic sequelae. Nine patients had fixed flexion deformity, four had procurvatum and one had recurvatum and one patient had combined deformity.

All cases were analysed with adequate x-rays two level fixation above and below the apex of the deformity was done with the hinges placed at the apex of the deformity. The motor was provided perpendicular to the axis of the hinge. Bony correction was performed in eight cases and rest were corrected by soft tissue distraction. After achieving correction fixator was retained for a month or two to prevent recurrence.

Out of the eight cases of fixed flexion deformity (FFD) in nine knees, full correction was achieved in seven knees. One adult with septic knee was planned for correction of deformity and fusion which was completed in 4 months time. Out of five congenital pterigium three had full correction. One case had complete recurrence which was recorrected completely in the second attempt and the 5th case had residual 20 degree deformity. Knee deformity in PPRP patient underwent SC osteotomy with good correction of the deformity which compensated the quadriceps gait. Post traumatic FFDs were corrected fully. The bony deformities of tibia namely the procurvatum and recutvatum deformities were corrected fully. Average fixator time is 7 months.

To assess the effect of deformity on Grip strength characteristics in the Rheumatoid Hands using force time curves. Forty seven (6 males and 41 females) patients with mean age 62 years (29–79 yrs) with Rheumatoid arthritis had their handgrip strength measured with closed fluid dynamometer generating force-time curves.

These were analysed further in blinded fashion for:

peak force;

Data was also collected on joint mobility, pain and disability using Patient Evaluation Measure (PEM) and Functional Disability Scores (FDS).

The patients were divided into five groups according to the degree of deformity: No deformity, ulnar deviation, Boutonniere, Swan neck or combined deformities (two or more deformities). These patient groups showed significant differences in grip strength (p value < 0.01). Patients with combination of deformities showed low peak and average forces as measured on force-time curves. The hands with Swan neck deformities had the highest variability in the plateau region of the curve and had the greatest disability scores both with PEM and FDS scores (P Value < 0.005). This group was particularly disabled (P Value < 0.007) being less able to sustain the grip over time.

Swan Neck Deformity causes the most significant dysfunction and this should be carefully considered when making decisions regarding surgery.

Treatment of a partial laceration in zone two of a flexor tendon remains controversial. The intact part of the tendon can sustain forces of normal un-resisted motion, and repaired partially treated tendons can actually be weaker than un-repaired ones. Trimming these lacerations has been shown to be beneficial in partially lacerated tendons with triggering or entrapment.

The purpose of this study is to observe the behaviour of a partially lacerated and subsequently trimmed tendon under strain, and measure their friction coefficient at different flexion angle and load. Ten long flexor tendons from long digit of turkey foot, along with the equivalent of A2 pulley were used. All experiments were carried out for intact, lacerated (50%) and trimmed tendon at 10, 30, 50 and 70 degrees of flexion and two load settings of 200 and 400g.

The friction forces were measured by the difference between the two load transducers and the friction coefficient was measured using this formula, μ = Ln[(F2/F1)]/Ø.

Friction coefficient (μ), Tension forces (F2 and F1), arc of tendon and pulley contact (Ø).

Results: Friction coefficient increased significantly by three folds (0.3) after laceration compare with intact tendon (0.12) at both loads. This was reduced significantly after trimming the tendon but the friction coefficient was still approximately twice the value of the intact tendon (0.2).

Triggering was noticed in all tendon lacerations. Triggering was reduced after trimming in 10 and 30 degrees of flexion but increased markedly at 50 and 70 degrees of flexion associated with tendon fragmentation at the trimmed area.

Trimming partially lacerated flexor tendons will reduce the gliding resistance of the tendon through the pulley but this can lead to further fragmentation and triggering at higher flexion degrees and loads.

Modern methods of deformity correction such as the Taylor Spatial Frame (TSF) allow correction of deformities to within tolerances of 1° and 0.5mm. Plain X-radiography using orthogonal views is the current standard for the assessment for the evaluation of angular limb deformities. CT has been used for the assessment of torsional and axial deformities but its use has not been described for the measurement of angular deformities. Furthermore, dedicated correction planning software (SpatialCad™) may allow more accurate deformity definition.

This study aims to evaluate the accuracy of CT and SpatialCad™ to measure angular deformities in vitro. A tibia sawbone was coated in radio-opaque paint. A TSF was mounted on it and an osteotomy made in the mid-diaphyseal region. Four deformities were created and imaged with plain radiography and CT. Four observers measured the deformities using paper and pencil, PACS and SpatialCad™ for plain radiographs and Spatial-Cad™ for the CT scout views. The variance of the mean response of observed differences between main treatment factors was measured using analysis of variance.

There was no significant difference in variability (precision) between observers or methods of measurement. However, measurements made with PACS and Spatial-Cad™ on plain radiographs, but not CT scout views, were also accurate.

There does not appear to be any evidence at present that the use of CT for measurement of angular limb deformity is justified over plain radiography. Spatial-Cad™ is designed to optimize deformity correction planning for use with TSF, but PACS appears to be adequate for use with other deformity correction systems.

To assess the outcome of knee “arthrodesis” using cemented Endo-Model knee fusion nail in failed Total Knee Replacement (TKR) with significant bone loss due to infection. This is a retrospective case study of seven patients with infected TKR and multiple surgeries with significant bone loss.

All patients had antibiotic loaded cement with a temporary K-nail as a first stage procedure to eradicate infection. All seven patients had “arthrodesis” performed using cemented modular Endo-Model Knee Fusion nail (Waldemar Link, Hamburg) by the senior author. Cement was used to hold the stems in the diaphyses and not used around the coupling mechanism. The “arthrodesis” relied entirely on the coupling mechanism which has been shown to have good axial and torsional rigidity by mechanical testing. Outcome was assessed using pre and post Visual Analogue Score (VAS).

Mean age was 72.3 years(62–86). Mean follow up was 39.6 months (7–68). The VAS pain score improved from pre-operative mean score of 7.9 to a postoperative score of 1.5. One patient suffered fracture of femoral cement mantle at 50 months who underwent a technically easy exchange revision. One patient had recurrent infection with distal femoral fracture at 36 months and was revised to distal femoral replacement.

The Endo-Model knee arthrodesis nail restores limb lengths, has good early results in terms of pain relief and provides a stable knee “arthrodesis” in cases where there is significant bone loss and extensor mechanism insufficiency following an infected TKR.

Extension contracture of knee is a disabling deformity in Indian population. The cause for the contracture may be congenital or acquired. The treatment for the contracted quadriceps is quadriceps release which is done either proximally or distally. The latter method is common and in adults it leaves quadriceps lag.

The method was originally described by Judet in 1932. It is modified and used in this series. It is a stepwise procedure :

Lateral release and joint adhesiolysis;

Thirty six patients with extension contracture of the knee have been undergone surgical release. There were 27 males and 9 females. 32 patients were adults and four were children. The aetilogy was post-traumatic in 31 out of which two were following epiphyseal injury. There were three cases of arthrogryposis, and one each of post osteomyelitic and post TKR. The age group ranged from 5 years to 45 years. Male:Female ratio was 27:9.

All patients were followed from minimum period of one year. One arthrogrypotic child developed skin necrosis which healed by secondary intention. Thirty-three patients achieved 0 to 120 degrees of ROM. Two of the arthrogrypotic patients obtained 0 to 60 and last patient had only 20. None of the patients had quadriceps lag. Judet quadricepsplasty has been demonstrated to be very effective in treating contractures of the knee.

Fibular hemimelia is associated with equinovalgus deformity of the ankle and hind foot and antero-medial bowing of tibia. A wedge shaped distal epiphysis of the tibia and tight posterolateral soft tissues play an important role in the pathogenesis of ankle valgus and lateral subluxation of foot. Tethering effect of fibular anlage may contribute to the deformities in the tibia and ankle. Lengthening procedures are associated with progression of these deformities.

The purpose of this study is to determine whether Exner Osteotomy and Excision of Fibular anlage will correct the valgus deformity of the ankle and antero-medial bowing of tibia. A bending osteotomy through the distal tibial physis as described by Exner and excision of Fibular Anlage was performed in six limbs in five children (4 boys, 1 girl) with fibular hemimelia. Histology of Excised Fibular anlage was studied under light microscopy. The mean age at the time of surgery was twenty two months (range: 8 months to 5 years).

The mean follow-up was two years and two months (13 months to 4 years and 8 months). Full Correction of ankle valgus and tibial bowing was achieved in three feet where, a cortical strut graft was used in the open wedge osteotomy. In two feet synthetic bone substitute was used. In these, tibial bowing corrected but slight ankle valgus remained. In one foot where synthetic bone substitute was used and the postoperative compliance with AFO was poor, bowing of tibia improved but ankle valgus recurred. Premature fusion of growth plate did not occur in any of the cases. Histology of fibular anlage showed replacement of bone tissue by mature collagen bundles surrounded by fibroconnective tissue.

Exner Osteotomy and Excision of Fibular Anlage in Fibular Hemimelia corrects the ankle valgus and antero-medial bowing of tibia.

Wire crossing angle affects the stability of circular fine wire frames. Anatomical atlases document safe ‘corridors’ to avoid neurovascular structures, although this may limit crossing angle. In the distal tibia the furthest posteriolateral safe corridor described is through the fibula. The present study describes a new and safe ‘retro-fibular’ corridor for wire placement in the distal tibia that provides a greater crossing angle. Two different methods of wire insertion are considered to determine which provides greater protection to neurovascular structures.

A dissection based study of 20 embalmed lower limbs divided into two groups. 1.8mm wires were inserted at increments along the tibia, from posterolateral to antero-medial, at 30–45 degrees to the sagittal plane. In the first group wires were placed against the posterior surface of the fibula and ‘stepped’ medially onto the tibia. In the second wires were inserted midway between the border of the fibula and tendoachilles. Standard dissection techniques were used to identify the path of wires and distance from neurovascular structures.

In group one distal tibial wires avoided the posterior tibial neurovascular bundle (mean distance 21.7mm) although passed close to the peroneal artery (mean distance 1.2mm). In group two both the posterior tibial and peroneal structures were avoided (mean distances 15.5mm and 7.1mm respectively). Comparison of the two groups shows a significant difference (p< 0.001).

Retrofibular wire placement is safe in the distal quarter of the tibia and facilitates an optimal crossing angle, although is not described in standard atlases. Insertion of wires mid-way between the posteromedial border of the fibula and the tendoachilles appears the most reliable technique.

Limb lengthening is described by means of external fixator in limb length discrepancy. Intramedullary distraction is a relatively new procedure undertaken infrequently. We present our initial results following the use of the ISKD for lower limb lengthening.

Methods: A retrospective review, over a three year period, revealed six patients (five femurs and one tibia) underwent lengthening by ISKD. Four of the femoral cases were secondary to trauma. The other femoral case and tibial case were secondary to congenital shortening.

All cases were male with mean age of 35 years (20 – 54 years). The mean total distraction was 42mm (10 – 65mm) and a mean daily distraction of 0.96mm/day (0.78 – 1.75mm). Mean time to full weight bearing was 12.5 weeks. The planned length of distraction was achieved in all patients undergoing femoral lengthening. Four of these patients regained full movement of the knee at 6 months and the other regained an arc of 5 – 105 degrees.

The tibial lengthening only achieved 28.5% of the desired length as a result of premature consolidation and poor patient compliance. There were no cases of infection, DVT, non-union or hardware failure. Three patients experienced no complications. One patient experienced premature consolidation and required repeat corticotomy. Two patients experienced inappropriate lengthening. One experienced distraction at the previous fracture site and as a result required 5 further operations and application Ilizarov frame. The other was as a result of a runaway nail achieving 56mm distraction in 32 days (1.75mm/day).

This review, although with small numbers, highlights that the ISKD is a satisfactory treatment for femoral lengthening although we experienced difficulties with tibial lengthening. Following our experience all patients require a CT scan preoperatively to confirm union at the fracture site. ISKD has been considered an option for femoral lengthening only.

The aims of this study were to review the management of open tibial fractures in our specialist ortho-plastic centre and to assess whether our practice concurred with the BAO/BAPS guidelines. A retrospective note review of patients with open tibial fractures was undertaken. Data was collected on time to referral to the plastic surgery unit and time to definitive soft tissue cover. Return of limb function was assessed using the Enneking score.

Forty five consecutive patients (27M vs. 18F), with an age range of 11–86 yrs (median age of 42 years), were treated using strict protocols. Seventeen cases were referred by the on-site orthopaedic unit, and 28 patients were from 7 neighbouring units. Time from injury to initial plastic surgery assessment ranged from 0 to 19 days, with a median of 4 days. Time from injury to definitive soft tissue cover ranged from 0 to 21, with a median of 5 days. 41/45 cases had definitive surgery within 5 days of initial plastics assessment. 5 patients with definitive treatment at days 4, 4, 7, 7, 12 developed superficial wound infection.

Patients referred from neighbouring units underwent on average 1 extra operation. We failed to detect any significant difference in return of function between the 2 groups indicating that referral to a specialist centre may produce equivalent functional return even if there is a delay in definitive treatment.

Open tibial fractures should be managed in a specialist centre, manned with dedicated lower limb plastic and orthopaedic reconstructive surgeons and followed up in a combined ortho-plastic clinic. However, more emphasis should be put on improved communication between referring units and the specialist centre.

Scarf osteotomy is a commonly performed method of hallux valgus correction. Release of deforming lateral soft tissue structures is an integral part of this correction. The aim of this study was to determine if there was any difference in the correction achieved by dorsal and transarticular releases as part of a scarf osteotomy.

This radiological study was performed at a single institution. One surgeon utilised the dorsal first web approach for the distal soft tissue release and one the transarticular approach. There were 23 patients in each group. The same post-operative regime was used on both sets of patients. Data was collected on hallux valgus angle (HVA), intermetatarsal angle (IMA) and AFS sesamoid scoring.

The pre-operative deformity as measured by hallux valgus angle and intermetatarsal angle where similar for both groups (p= 0.25, 0.79 respectively) with a significant difference in severity of AFS scoring in the dorsal group (p < 0.001). Patients who underwent a dorsal approach release had a mean improvement in IMA of 5.46 degrees compared to 3.86 in the transarticular group. The HVA improved by 17.92 degrees in the dorsal group compared to 8.08 in the transarticular group. Both these results were statistically significant (p= < 0.01,< 0.002 respectively). There was a statistically significant difference in number of patients returning to within normal limits of the HVA (p= < 0.05); 18 patients returned to a normal hallux valgus angle after undergoing the dorsal approach compared to 9 patients in the transarticular group.

Our study shows that when performing a distal soft tissue release in conjunction with a scarf osteotomy for correction of hallux valgus, a dorsal first web approach is significantly better at correcting the HVA as compared to a transarticular approach. We would, therefore, recommend the use of a dorsal approach when performing this surgery.

The Ilizarov technique can be used to achieve bony union in high energy trauma and in non-union. There is much interest in the augmentation of bone healing using growth factors, GPS II collects the patients own platelets into a highly concentrated formula. Activated platelets release growth factors that may stimulate fracture healing.

We used the GPS II system in 13 cases of either high-energy trauma (2 cases) of non-union (11 cases) treated with the Ilizarov Circular frame in our institution. The group included two tibial fractures, eight tibial, one femoral and two ulnar non-unions. The minimum follow up of a year. The average age of the patient was 45 (22–66). We observed complications and measured time to clinical and radiological union from the start of treatment with circular frame.

No complications associated with GPS. One patient had an infection remotely in the limb resulting in amputation. All fractures and non-unions went on to solid bony union. The average time to radiological union was 21 weeks (range 13–36 weeks). Frame removal in these cases was 6.5 months (range 4–10 months). No patient underwent any further surgical intervention.

This pilot study features a heterogenous group of patients in which it is difficult to assess the role of GPS II. The use of GPS II, however, was uncomplicated in our study. The use of GPS II may act as a adjuvant therapy in the treatment of high energy trauma and non-union treated with the Ilizarov technique. Furthers studies are required to investigate the efficacy of GPS II in the management of non-union.

To evaluate the effects of eccentric strengthening exercises (ESE) in athletic patients with Achilles tendinopathy. Forty five athletic patients (29 men, average age 26 years; 16 women, average age 28 years; average height: 173 ± 16.8, range 158 to 191; average weight 70.8 kg ± 15.3, range 51.4 to 100.5) with clinical diagnosis of unilateral tendinopathy of the main body of the Achilles tendon completed the VISA-A questionnaire at first attendance and at their subsequent visits. The patients underwent a graded progressive eccentric calf strengthening exercises programme for 12 weeks.

The mean pre-management VISA-A scores of 36 (SD 23.8; 95% C.I.: 29 – 46) improved to 52 (SD 27.5; 95% C.I.: 41.3 – 59.8) at the latest follow up (p = 0.001). Twenty seven of the 45 patients responded to the eccentric exercises. Of the 18 patients who did not improve with eccentric exercises, 5 (mean age: 33 years) improved with two peritendinous aprotinin and local anaesthetic injections. 10 of the 18 patients (9 men, mean age 35 years; 1 woman aged 40 years) who did not improve with eccentric exercises and aprotinin injections proceeded to have surgery. The remaining three patients (3 women, mean age 59.6 years; 2 men, mean age 63 years) of the 18 non-responders to eccentric exercises and aprotinin injections declined surgical intervention.

ESE in athletic patients provide comparable clinical outcome compared to our previous results in non-athletic patients. ESE are a viable option for the management of AT in athletes, but, in our hands, only around 60% of our athletic patients benefited from an intensive, heavy load eccentric heel drop exercise regimen alone. If ESE fail to improve the symptoms, aprotinin and local anaesthetic injections should be considered. Surgery is indicated in recalcitrant cases after 3 to 6 months of non operative management.

To test the knowledge of clinicians in Orthopaedic clinics and Emergency departments of the surface anatomical landmarks that should be examined during assessment of foot and ankle injuries. Specifically trained assessors observed 109 clinicians examining 6 anatomical landmarks on uninjured subjects. Each landmark was chosen for their relevance in assessment of foot and ankle injuries. The landmarks were the medial malleolus, lateral malleolus, fibula head, navicular, base of the 5th metatarsal and the anterior talo-fibular ligament (ATFL).

Two participants failed to identify a single landmark. Of 109 assessed, 27% correctly identified all 6 landmarks. The average correctly identified by each clinician was 4.1 with a standard deviation of 1.5 and range of 0–6. One hundred and seven clinicians correctly identified the lateral malleolus, the most consistently identified. The most poorly identified landmark was the ATFL, by 45%.

The knowledge of surface anatomy overall by junior Orthopaedic and Emergency clinicians was found to be poor and only seems to significantly improve once higher specialty training is reached. Despite the potential for subjectivity and bias the authors believe the methodology is sufficient to demonstrate a lacking in anatomical knowledge amongst clinicians. Poor anatomical knowledge leads to inaccurate examination. This can lead to incorrect diagnoses or even mal-treatment of patients. Clinicians are becoming more reliant on potentially unnecessary and expensive imaging investigations. They have neglected the basic art of physical examination based on sound knowledge of human anatomy. At present, the authors believe that the anatomical teaching in undergraduate medicine is inadequate.

We aimed to assess the long term results of patients who underwent Autologous Chondrocyte Implantation (ACI) for osteochondral lesions of the talus. Between 1998 and 2006, 28 patients underwent ACI for osteochondral lesions of the talus. All these patients were prospectively reviewed and assessed for long term results. Outcomes were assessed using satisfaction scores, Mazur ankle score and the AOFAS score, and Lysholm knee score for donor site morbidity.

The 28 patients who underwent the procedure included 18 males and 10 females. Follow up ranged from 1–9 years. In all patients, there was an improvement in the Mazur and AOFAS ankle scores and the Lysholm scores showed minimal donor site morbidity. Improvement in ankle score was independent of age and gender. The better the pre-op score the less the difference in post-op ankle scores. Patients were unlikely to benefit with pre-op ankle scores over 75.

The mid to long term results of ACIs in the treatment of localised, contained cartilage defects of the talus are encouraging and prove that it is a satisfactory treatment modality for symptomatic osteochondral lesions of the talus. Complications are limited. However, in view of limited number of patients, a multi-centre randomised controlled study is required for further assessment.

Chronic exertional compartment syndrome of the foot is well recognised. There has been debate over the exact number and location of compartments. While the medial compartment has been consistently reported, the exact anatomy of the fasciotomy has been poorly documented in orthopaedic literature.

Over a four year period (2003–7) five patients (seven feet) with history and examination findings compatible with chronic exertional compartment syndrome affecting the medial compartment of the foot were treated in our unit. There were three female patients and two males, average age 23 (17–34).

Assessment was made using the Stryker compartment pressure monitor inserted into the compartment following exertion. The measurements were compatible with chronic exertional compartment syndrome according to the Pedowitz criteria. The patients then underwent complete surgical release of the medial compartment of the foot. This involved two small oblique incisions, over the proximal and distal ends of the muscle belly of abductor hallucis, the fascia on the superficial and deep surfaces was then released, thus releasing the distal end of the tarsal tunnel. Decompression was bilateral in one, sequential in one and unilateral in three. Three patients also had surgical treatment of chronic compartment syndrome elsewhere in their lower limbs. One patient underwent a simultaneous calcaneal osteotomy for a planovalgus foot.

Preoperative post exertional compartment pressure measurements were 67.8 (32–114) at 1 minute and 50.2 (28–97) at 5 minutes. At an average of 21 (9–57) months follow up all but one patient had significant relief of their symptoms.

We recommend that the surgical treatment of chronic exertional compartment syndrome affecting the medial compartment of the foot should involve full release of the fascia both superficial and deep to abductor hallucis. It is safe to perform this bilaterally and in association with other lower limb decompressions as required.

A linkage-based mathematical model was used to design a ligament-compatible prosthesis to keep certain ligament fibres isometric during passive motion. The sagittal plane talar component radius is about 50% longer than that of the normal talus, the tibial component is spherically convex. A fully conforming meniscal bearing is interposed between them. Experiments in cadaver specimens confirmed the mathematical prediction that the bearing moves forwards on both metal components during dorsi-flexion and backwards during plantar flexion.

Between July 2003 and July 2008, the prosthesis was implanted into 250 patients at nine hospitals in Northern Italy. By November 2007, 158 in 156 patients were seen at least six months post-operatively. Mean age was 60.5 years. The diagnosis was post-traumatic osteoarthritis in 127, primary osteoarthritis in 17, rheumatoid arthritis in 10.

The mean follow-up was 32.5 months. The pre-operative AOFAS score of 36.2 rose to 75.9, 79.3, 77.9, and 79.0 respectively at 12, 24, 36, 48 months. Dorsi-flexion increased from 0.1° to 9.7°, plantarflexion from 15.1° to 24.6°. In 30 patients at one hospital, the range of postoperative motion, 14° – 53°, was significantly correlated to the range of bearing movement on the tibial component, 2mm–11mm, measured radiologically, (r2 = 0.37, p < 0.0005).

By December 2007, 2 revision operations had been performed at 24 months, one for unexplained pain not relieved by a successful arthrodesis, one in a patient with Charcot-Marie-Tooth disease. There were no device-related revisions (loosening, fracture, dislocation). The Kaplan-Meier survival rate (component-removal as end-point) at 4 years was 96% (Confidence interval 90–100%).

Early clinical results have demonstrated safety and efficacy. The survival rate at four years compares well with multi-centre 5-year rates published by the Swedish (531 cases, survival 78%), Norwegian (257, 89%) and New Zealand (202, 86%) registries.

There is limited literature available looking into circumstances surrounding the development of stress fracture of the medial and lateral malleoli after ankle replacement. We present the preliminary results of a prospective study examining the effect of ankle replacement upon local bone mineral density and the phenomenon of stress shielding.

We aimed to assess the effect of ankle replacement loading of the medial and lateral malleoli, by analysing the Bone Mineral Density (BMD) of the medial and lateral malleoli before and after Mobility total ankle replacement.

Ten consecutive patients undergoing Mobility total ankle replacement for osteoarthritis had pre-operative bone densitometry scans of the ankle, repeated at 6 months after surgery. The bone mineral density of a 2 cm square area within the medial malleolus and lateral malleolus was measured. The pre-operative and postoperative bone densitometry scans were compared. The relation between the alignment of the tibial component and the bone mineral density of the malleoli was also analysed.

The mean preoperative BMD within the medial malleolus improved from 0.57g/cm2 to mean 6 months postoperative BMD of 0.62g/cm2. The mean preoperative BMD within the lateral malleolus decreased from 0.39g/cm2 to a mean 6 months postoperative of 0.33g/cm2. The mean alignment of the tibial component was 88.50 varus (range 850 varus to 940 valgus). However, there was no correlation between the alignment of the tibial component and the bone mineral density on the medial malleolus (r = 0.09, p = 0.865).

The absence of stress shielding around the medial malleolus indicates that ankle replacements implanted within the accepted limits for implant alignment, load the medial malleolus. However, there was stress shielding over the lateral malleolus resulting in decreased BMD in the lateral malleolus.

We aim to assess the long term functional and symptomatic outcome of patients after open reduction internal fixation (ORIF) of the ankle. A retrospective telephone interview of patients (n=113) in years five, six and seven after ORIF of the ankle was conducted. The Olerud-Molander Ankle Score (scale 0–100) and SF-12 Health Survey scores were utilised to assess symptomatic and functional outcome. Fractures were classified in accordance with the Danis-Weber system. All patients were operated upon in the same unit by the same group of surgeons.

Sixty five patients were male and 48 female. The mean age was 56 (range 15–96). Patients with Weber B fractures (n=83) had a mean OMAS of 89.2. Those with Weber C fractures (n=25) had a mean OMAS of 85.4. Five patients had isolated medial malleolar fractures. At five to seven years post-operatively, 67.3% of patients were symptomatic. Of these, 75% complained of swelling; 39% of pain and 30% of stiffness whilst 19.5% of all patients felt they had not returned to their pre-operative functional level. Regardless of fracture type or follow up time, patients under 40 years old, had a significantly higher mean OMAS (90.7) as compared to those between 40 and 65 years old (85.3) (p=0.024). There was no significant difference in the mean OMAS of patients followed up at five or seven years post operatively or between those with Weber B or C fractures.

Patients suffer ongoing symptomatic and functional problems up to seven years after ORIF of the ankle and a significant number do not return to their pre-injury functional state. Patients under 40 years old had a better outcome as compared to older patients, whilst Weber type or year of follow up did not affect outcome. Surgeons should counsel patients pre-operatively regarding possible long term problems when undertaking ankle fracture fixation.

Total Ankle Arthroplasty (TAA) using the uncemented three component mobile design has shown encouraging results. There is limited literature on the optimal postoperative management. In our centre, TAA patients are mobilised 48 hours after surgery without a short leg plaster. The aim of this prospective audit was to measure the outcomes of these patients to ascertain if this is a safe and effective protocol.

Patients who underwent primary TAA between March 2006 and March 2008 were invited to participate in the audit. Assessment included patient questionnaires which collected demographics, height and weight, Foot and Ankle Outcome Score (FAOS) and Short-Form-36 (SF-36). Clinical examination collected American Orthopaedic Foot and Ankle Score (AOFAS). Data was collected pre-operatively and at 3 and 6 months after surgery.

A total of 48 ankle replacements in 46 patients were included. Primary diagnosis was osteoarthritis (25), post-traumatic osteoarthritis (9), and rheumatoid arthritis (12). Mean age was 63 years (range 33 to 83) and the majority were males (29, 60%). The average body mass index was 28 (SD 5.3). There were significant improvements to 3-months after surgery for AOFAS (mean 29 to 76, p< 0.0001), FAOS (mean scores changes: Pain 36 to 72, Function 41 to 68, Stiffness 38 to 65, p< 0.001) and physical domains of the SF-36 (means score changes: Physical Functioning 25 to 39, Role Physical 27 to 40, Bodily Pain 29 to 48 and Vitality 42 to 50, p< 0.05). All outcome scores were maintained with a non-significant trend for better scores from 3 to 6 months.

These early results demonstrate encouraging outcomes for TAA patients who are mobilised early after surgery without a short leg plaster. Further studies of post-operative management are needed to compare outcomes after TAA between patients undergoing this protocol and patients who are immobilised in plaster.

It is generally accepted that urgent debridement and fixation of open tibial fractures minimizes the risk of infection. Traditionally surgeons follow the unwritten six hour rule. The purpose of this study was to determine the association between time to definite surgical management and rates of infection in open fractures of the tibia.

One hundred and twenty-seven patients with one hundred and twenty-eight open tibia fractures were retrospectively reviewed. Of these ninety patients with ninety-one one fractures were available for this study. All patients were followed up to clinical and radiological fracture union or until a definitive procedure for infection or non-union had been carried out.

The time from injury to surgery ranged from 2 hours 35 minutes to 12 hours with an average time of 5 hours 40 minutes. There were 24 Gustillo type I fractures (26.37%), 11 type II fractures (12.08%), 23 type IIIA fractures (25.27%) and 33 type IIIB fractures (36.26%). 5 patients (5.49%) in this study went onto develop a deep infection and there were 4(4.39%) non-unions. No infection occurred when the surgery was done within 2 hours. All the 5 infections in this study occurred in patients operated between 3 to 8 hours of the injury and were all in Gustillo Grade III fractures. The average time to treatment was not significantly different between the infected versus non infected group across all fracture types. There was no increase in infection rate in those treated after 6 hours compared to those treated within 6 hours.

The risk of developing an infection was not increased if the primary surgical management was delayed more than 6 hours after injury provided intravenous antibiotics were administered on presentation to the emergency department. The Gustillo grading of open fractures is a more accurate prognostic indicator for developing an infection.

We aim to evaluate the effect of fasciotomies following compartment syndrome on the healing of closed tibia diaphyseal fractures. Between January 2002 and January 2005 165 patients were treated in our institution with closed tibial diaphyseal fractures. Patients were divided in to two groups; Group A (study group) consisted of patients that, after surgery, developed compartment syndrome and were submitted to fasciotomies and group B (control group) of patients who underwent reamed IM nailing and did not require such intervention.

Patients with open fractures, pathological fractures, revision surgery, severe brain injuries, prolonged ITU stay and severe co-morbidities were excluded. Fracture pattern, ISS score, smoking habits, drugs intake, mode of mobilization and additional procedures were prospectively documented. Fracture healing more than 24 weeks was defined as delayed union and over 36 weeks as non-union. All patients had been followed-up clinically and radiologically until fracture union.

One hundred twenty five out of 165 patients fulfilled the inclusion criteria for this study. 30 patients were classified in group A and 95 in group B. Eighteen patients of group A required skin graft coverage after the fasciotomies. There was no difference between the two groups in terms of the studied parameters. Four patients from group A and one from group B, went to non-union and required second procedures to achieve union. These patients were excluded from the final analysis. Delayed union occurred in 11 (36.6%) patients in group A and in 10 (10.5%) patients in group B (P< 0.05). Overall, fracture healing was prolonged in the fasciotomy group but the difference was not statistical significant, 24.27 weeks (10 – 48) versus 22.19 (12 – 40), (P= 0.157) in group A and group B respectively.

Compartment syndrome and fasciotomies is associated with delayed fracture healing. Nevertheless, this delay was not statistically significant different.

We investigated whether lateral compression type I injuries of the pelvic ring are inheritably mechanically stable. Between January 2005 to January 2007 all consecutive admissions of a tertiary referral center for pelvic ring reconstruction with a LC I injury pattern were eligible for inclusion. Exclusion criteria were other patterns of pelvic ring injuries.

All patients underwent radiological assessment including AP pelvis, inlet/outlet views and CT. Patient demographics, mechanism of injury, other associated injuries, ISS, length of hospitalisation, type of operation, mode of mobilization, preoperative and postoperative visual analogue score pain VAS and follow up until fracture union were prospectively documented. Mechanical stability of the pelvic ring was assessed in the operating theatre under general anaesthesia. Instability was defined as displacement > 2 cm of the anterior or posterior elements. The minimum follow up was 12 months.

Of 210 patients admitted with pelvic fractures, 40 fulfilled the inclusion criteria (LC1 type). There were 23 female 17 male and with a mean age of 33.5 (range 18–68). The mean ISS was 10 (range 9–19). 23 patients (group 1) were found to have more than 2 cm rotational displacement during EUA and were stabilised with SI screws posteriorly and a combination of retro-pubic screws, external fixator or plating anteriorly. 17 patients (group 2) exhibited minimal displacement less than 5mm and were not stabilised. Rotational instability > 2cm was characterised by complete fracture of the sacrum posteriorly. Stabilisation of the pelvic ring in group I was associated with a significant reduction of the VAS within 72 hours from surgery, early ambulation and discharge from the hospital.

This study supports the view that not all LCI fracture patterns are mechanically stable. Examination under anaesthesia of the pelvic ring can assist the clinician in the decision making progress.

The safety and efficacy of bone-healing enhancement with Bone Morphogenetic Protein-7 (BMP) has been studied in the clinical setting of persistent post-traumatic and post-partum pelvic instability. Prospective collection and analysis of all cases with pelvic ring instability after trauma or childbirth, treated with reconstruction and local application of BMP-7. Patient demographics, hospitalisation, operative interventions before and after the BMP-7 grafting, and follow-up data were recorded and evaluated. The median follow-up period was 1 year (range 12 to 18 months).

Over a two-year period (March 2005 – January 2007) nine patients (8 females) with median age of 39 years (31–62) were operated for persistent pelvic instability and pain. The mean number of previous operations was 1,6 procedures. Reconstruction of the pelvic ring included 4 cases of post-partum pubic symphysis instability, 2 traumatic non-unions of pubis symphysis and 3 sacroiliatis (1-septic and 2-aseptic). Reconstruction included double plating of pubis symphysis (4-cases), external pelvic fixation (2-cases), sacroiliac screw fixation (1-case) and anterior sacroiliac plating (2-cases).

In 4 cases BMP-7 was used alone; in 5 it was used together with iliac crest autograft. All patients were mobilizing with a wheelchair for a period of 8 weeks (6–12) before progressing to full weight bearing. Clinical and radiological union occurred in 8/9 cases at a median time of 14 weeks (range 12–20). One female patient with post-partum pubic symphysis instability and a chronic psychiatric disorder is still complaining of pain despite the radiological evidence of progress of fusion. The rest reported resolution of symptoms. No local or systemic complications or adverse events associated with the use of BMP-7 were recorded.

The application of BMP-7 alone or supplementing autografting has been proven to be radiologically 100% and clinically 90% successful and safe following pelvic ring reconstruction as seen in this series of patients.

We aimed to determine multi-modality outcomes in surgically treated patients with high energy pelvic ring injuries. A retrospective cohort study of all patients with pelvic ring fractures treated surgically within our specialist tertiary referral unit was undertaken between 1994 and 2007. Case-notes and radiographs were reviewed and patients were contacted by postal questionnaire. Outcome measures were return to work, return to pre-injury sports and social activities, and the Short Form-36 (SF-36) outcome tool. Injuries were classified using the Young and Burgess (YB) classifications.

There was a response rate of 70% (145 of 209 patients), 74% of the study subjects were male. Average age at injury was 40 yrs (16–74 yrs). Average follow up was 5.3 yrs (1–12 yrs). There were 45 Antero-Posterior Compression (APC) injuries, 51 Lateral Compression (LC) injuries and 49 Vertical Shear (VS) injuries. 58% of the APC injuries had returned to work (including changed roles at work), compared with 68% of the LC injuries and 51% of the VS injuries. 27% of the APC injuries had returned to their pre-injury sports, compared with 39% of the LC and 33% of the VS injuries. 64% of the APC injuries had returned to their pre-injury social activities compared with 77% of the LC and 49% of the VS injuries.

The SF-36 average Physical Functioning Score was better for the LC group (73.2) than the APC (61.7) and VS (63.3) groups. This general trend was repeated when the General Health and Social Functioning scores were reviewed.

These results illustrate the long-term morbidity associated with pelvic ring injuries and relationship with injury subtypes. The LC injuries appear to have better outcomes with all outcome measures than APC and VS injuries. Further studies are underway to look at other factors and their relationship to outcomes.

The purpose of this study was to evaluate the efficacy of autologous cancellous bone grafting (ABG) for the treatment of long bone fracture non-unions. Patients who were treated with ABG for fracture non-unions of the lower extremities were identified from our prospectively entered database. Non-union was defined as failure of the fracture to unite within a period of 9 months. Demographics, comorbidities, medications, complications and surgical outcomes were all recorded and subsequently analysed. Chi square test was used to analyse the results.

In total 82(54 male) patients met the inclusion criteria. The mean age was 43.6 years (range 18–78). Ten patients were diagnosed with femoral and 72 with tibial fracture non-unions. Fifty three (64.6%) were open fractures at presentation. In the tibial non-union group, initially, 67 fractures were stabilised with IM nailing and 5 with plating. During revision surgery, 33 patients underwent exchanged nailing and ABG whereas 34 received ABG without revision of the metal work.

All five tibial plantings required re-plating and ABG. In the femoral non-union group, five fractures were initially stabilised with IM nailing and the rest with plating. During revision surgery, six patients underwent change of fixation (exchange nailing) and ABG and four received only ABG. Overall 73/82 patients progress uneventfully to union and the success rate was 89%. A second and a third attempt of ABG was made for 6/86 patients (7.31%) and 2/82 patients (2.44%) respectively, till clinical and radiological union. All but one of the patients united their fractures. One patient underwent amputation due to underlying osteomyelitis.

The mean time to union following the ABG procedures was 8.4 months (range 3–18). Autologous bone grafting is an effective method of treating fracture non-unions. Success rates of as high as 89% can be achieved as seen in this series of patients.

Comminuted subtrochanteric fractures pose a clinical challenge; locking plate technology has been theorized to offer treatment advantages. A comminuted subtrochanteric femoral fracture model was created with a 2 cm gap below the lesser trochanter in fifteen matched pairs of human cadaveric femora confirmed to be non-osteoporotic. The femora were randomized to treatment with a trochanteric femoral nail (TFN), proximal femoral locking plate (PFLP), or 95° angled blade plate (ABP). Each was tested under incrementally increasing cyclic load up to 90,000 cycles to simulate progressive weight bearing during three months.

The TFN was the strongest implant: it withstood significantly more cycles, failed at a significantly higher force, and withstood a significantly greater load than either plate (p< 0.001). Varus collapse was significantly lower in the TFN construct (p< 0.0001). Mode of failure differed among implants, with damage to the femoral head through implant cut-out in five of ten blade plate specimens and two of ten nail specimens, whereas no damage to the femoral head bone was observed in any of the PFLP specimens.

The TFN was biomechanically stronger than the PFLP and this may have clinical relevance during the slow healing of subtrochanteric femoral fractures. The PFLP was biomechanically equivalent to the ABP but failure occurred without significant damage to the femoral head, suggesting that although biomechanically equivalent, the PFLP might have clinically relevant advantages in its mode of failure over the ABP.

Historically the management of distal radial fracture has been often inadequate. It can be difficult to internally fix complex distal radial fractures with conventional plates. The fracture often collapses with metalwork failure. Literature suggests that malunion may lead to painful wrist with loss of function. In recent years fixed angle locking plate has been advocated for treatment of complex distal radius fracture. Our aim was to assess to assess the effectiveness of the volar locking plate (DePuy) in maintaining fracture reduction in distal radial fractures.

Radiographs of 170 distal radius fractures treated by the DVR plate were analysed. Fractures were classified according to the Melone and AO classifications. The post injury, intra-operative, 6 weeks postoperative and final postoperative radiographs were reviewed to obtain measurements for radial height, radial slope and volar inclination. The measurements were correlated with fracture pattern, locking screw length, presence or absence of radial styloid screw and plate placement in relation to the wrist joint. The results were analysed statistically using Wilcoxon signed rank test.

Radiologically there was minor loss of radial height, slope and volar inclination but this was not statistically significant. There was a statistically significant correlation between complexity of fracture and loss of radiological parameters. There was no statistically significant correlation between loss of radiological parameters and screw length, plate placement or presence or absence of radial styloid screw.

The DVR volar locking plate appears to maintain a satisfactory reduction of the fracture except for some complex fractures with dorsal comminution in which case dorsoradial plates may be preferable.

Ankle injuries in cricket fast bowlers are of topical interest with a number of elite pace bowlers recently sustaining injuries. Previous biomechanical research has concentrated on the injury risk to the fast bowler’s lumbar spine with no research focused on the leading leg and specifically the ankle biomechanics of the fast bowler and its predisposition to injury.

We investigate the leading leg biomechanics in maximal and submaximal fast bowling. Ten fast-medium paced bowlers of elite level had their leading leg biomechanics assessed during their bowling action. Using a nine camera infra-red ViconTM 612 motion analysis system linked to a KistlerTM 9281CA force platform the moments of the subjects leading leg during their delivery stride was analysed. Each subject performed ten trials at a maximal ball release speed (> 97km/hr) and ten trials at a submaximal ball release speed (< 97km/hr) with the speed of the ball tracked by a SR3600 radar gun.

All three large joints of the leg were observed and joint moments examined in both directions of all three orthogonal planes giving a total of eighteen joint moments investigated. Of these results only the difference in the ankle plantar flexion was found to be significant. The average ankle plantar flexion peak moment in the maximal and submaximal ball release speed groups were found to be 2.008Nm/kg and 1.790Nm/kg respectively. This difference was statistically significant (p< 0.02)

The increased ankle plantar moment reflects the important role the ankle plays in the generation of extra ball release speed in the fast bowler. However this role does place increased stress on the ankle which may predispose it to injury. This study suggests that the ankle plays a significant role in the fast bowler’s delivery action and post injury rehabilitation needs to take this into consideration.

Fractures of humeral shaft are commonly seen in orthopaedic practice accounting for approximately 3% of all fractures. Treatment of these injuries continue to evolve as advances are made in both nonoperative and operative management. We performed a prospective study in the management of fractures of diaphysis of humerus by interlocking nail fixation and dynamic compression plating (DCP) was undertaken over a period of 3 years.

Forty five patients with humerus fracture were treated with either interlocking nailing or plating. Rodriguez-Merchan et al criteria was used to compare results of both groups postoperatively. Fractures with unacceptable alignment was the most common indication for operative intervention (53%). While only 50% of the interlocking group had healed by 16 weeks, 75% of the plating group had united by this time. Overall results (Rodriguez-Merchan) show 65% excellent and good results in interlocking group and 93% similar results in the plating group. Postoperative radial nerve palsy was not seen in the interlocking group but was noted in 6.25% of the plating group. All of them recovered uneventfully with time.

Plating is generally considered gold standard and to have predictable results in treatment of humerus shaft fractures. We have noted earlier union and better overall results in the plating group. Interlocking nailing is particularly preferable in communited, segmental and pathological fractures.

Repair of chronic Achilles tendon rupture is technically complex. Flexor jallucis longus (FHL) and peroneus brevis (PB) tendon transfers have been described, but the mechanical properties of these tissues have not been well reported.

The FHL, PB and tendo achilles (TA) tendons were harvested from 17 fresh frozen human cadavers free of gross pathology (mean age 69 years). Samples were tested in uniaxial tension at 100% per minute. Samples were secured using special jigs for the bony aspect or by freezing the tendons in cryogrips using liquid carbon dioxide. The peak load (N), linear stiffness (N/mm) and energy to peak load (N*mm) were determined. Mechanical data was analysed using one way analysis of variance (ANOVA) followed by a Games Howell multiple comparison post-hoc test.

Fifty one tendons were harvested and mechanical testing was successfully completed in all samples apart from one PB that slipped from the grips during testing (sample was omitted from the analysis). The mean ultimate loads differed for each group, with the TA tendons being the strongest (1724.5 N ± 514.3) followed by FHL (511.0 N ± 164.3) and PB (333.1 N ± 137.2) (P< 0.05). Similar results were found with respect to energy, with TA tendons absorbing the most energy followed by FHL and PB (P< 0.05). Stiffness for the TA tendons (175.5 N/mm ± 94.8) was greater than FHL (43.3 N/mm ± 14.1) and PB (43.6 N/mm ± 18.9), which did not differ from each other.

FHL is stronger than PB, but have similar stiffness. The mechanical properties of PB and FHL were both inferior to TA. Graft stiffness appears to be an important variable rather than ultimate load based on the clinical success of both techniques.

Both acute and chronic hamstring injuries are disabling injuries, and occur almost entirely to elite athletes. We report our experience in the management of injuries of this location. Twenty seven patients (29 injuries) were included in the present study. They completed a questionnaire detailing their pre-injury activity, injury mechanism, rehabilitation and a subjective assessment of their recovery. At clinical examination pain and hip motion were evaluated.

Hamstring injuries predominantly affect males on the left side. Most procedures carried out were explorations with limited debridement and suture of the tendon. One third of patients felt they had returned to 100% of their pre-injury level, and 33% felt they had returned to 80–90% of their pre-injury level, the rest varied between < 20–80%. 45% gave a value of zero on the visual analogue pain scale independent of activity, those who gave a value above this had pain during active sports but not at rest.

Early repair leads to a much better recovery of muscle function, especially when dealing with complete avulsions. Lesions to the origin of the hamstring can be successfully managed if a high suspicion for the condition exerted.

Tibial shaft fracture occurs commonly in the young active population with high demands. Tibial fracture is potentially life changing. There are no published studies with long-term follow-up to provide accurate prognostic information regarding return to leisure activities, employment and driving.

We aim to define the patient demographic and mechanism of injury and quantify the time period following tibial shaft fracture to return to sport and sporting level achieved at long-term follow-up. A retrospective multi-centre study was performed. Data collection was by questionnaire including Tegner activity scale score for sporting level and closed questioning on employment and driving.

Ninety-three patients were recruited with an average 46 month (18–64mo) follow-up period. Patients were predominantly male (77%) with a median age at injury of 37 years. Road traffic accidents were responsible for 43% of injuries; sport 31%; falls 25% and assault 1%. High energy mechanisms accounted for 49% of injuries Seventy-eight percent of patients felt that prognostic information given at the time of injury was inaccurate.

At follow-up, only 31% had regained their original level of sporting ability. Median Tegner score prior to injury score was 5 and at 18 months the mean score fell by 1.85. Patients sustaining high energy injuries were worst affected, dropping an average of 2.13 compared to low energy mechanisms with an average fall of 1.35 on the Tegner scale (p=0.503). High demand patients had a greater reduction in functional outcome, with a fall of 0.8 for patients with pre-injury activity level of 1–3 compared to the fall of 2.6 on the scale for more active patients scoring 7–9 pre-injury.

Tibial fracture can result in significant long-term morbidity. Patients sustaining high energy injuries and high demand patients have significantly worse outcome. Patients are unlikely to achieve their pre-injury level of sporting activity at 2 years.

The purpose of the study was to establish if there is a consensus amongst knee surgeons in U.K. related to rehabilitation protocols following microfracture/drilling procedure performed for treatment of full thickness chondral lesions of the knee. Successful rehabilitation is accepted to be essential for achievement of best results.

A questionnaire was produced including questions about use of a CPM machine, use of a brace, weight-bearing status, use of an exercise bike, time allowed for patient to resume running, time allowed for patient to return to contact sports and surgeon’s expectancy of when symptoms will plateau. A simple scenario was put at the beginning of the questionnaire: “ A 23 year-old rugby player sustained a full thickness 1.5 x 1.5 cm chondral fracture on

the medial femoral condyle and

The lesion is treated using microfracture or a standard debridement method – post-operatively how is the patient managed?”. Questions were asked with regard to each site. The questionnaire was sent to BASK members. One hundred and twenty surgeons replied.

Analysis of responses showed an unexpected variability regarding the rehabilitation for patients having treatment for a full thickness chondral lesion, with no common agreement (less than 50%) even about such aspects as the use of CPM, allowed range of motion, weight bearing status or return to sport.

There is a marked disparity amongst knee surgeons in UK regarding the protocol of rehabilitation after treatment for full thickness chondral lesions of the knee. The majority of patients suitable for microfracture are young and active and a successful rehabilitation program is crucial to optimize the results of surgery. There is a need for development of accepted practice guidelines, to standardise the outcome for these patients.

We aim to assess the clinical and radiological outcome following cartilage repair in the knee using the TruFit plug (Smith & Nephew). Eleven active sporting patients underwent cartilage repair using TruFit plugs between February 2006 and August 2007. Postoperatively patients were touch weight bearing for 2 weeks and partial until 4 weeks.

Data was collected prospectively, patients underwent clinical review and completed Lysholm, IKDC subjective, Tegner, KOOS and SF-36 scores pre-operatively and at 6 monthly intervals. One patient has been excluded from the analysis as she emigrated and was lost to follow up. The remaining 10 patients (mean age 35 years (21–49)) had defects on the medial femoral condyle (n=6), lateral femoral condyle (n=3), and lateral trochlea (n=1). Patients received one (n=5), two (n=3) or three (n=2) plugs and four were primary procedures, and six revision procedures (1 failed OATS, 5 failed microfracture). Eight implantations were performed arthroscopically and, and two were mini-open. All patients were reviewed at 12 months, five were reviewed at 18 months and four have also been reviewed at 24 months.

Statistically significant improvements from mean pre-operative scores are seen at 12 months; Lysholm (48.3 to 71), IKDC Subjective (37.7 to 65.1), Tegner (2.4 to 4.6), SF36 physical (39.5 to 50.3) and all components of KOOS. These improvements are maintained at the latest follow up. MRI evaluation including T2 mapping demonstrates reformation of the subchondral lamina, resorption of the graft and a similar signal from neo-cartilage as that of adjacent native cartilage.

TruFit plugs offer an exciting novel solution for cartilage repair in the knee with advantages of low morbidity and rapid recovery without the need for prolonged non-weight bearing. The implant may be suitable for small lesions only and further prospective study is required to establish long-term outcome.

The purpose of this study was to evaluate and assess the sporting and physical activities of patients who have undergone hip resurfacing. One hundred and seventeen patients who underwent hip resurfacing between 2003–2007 were reviewed.

Demographic data such as age, sex and comorbidities were recorded. University of California and Los Angeles (UCLA) activity level ratings and Oxford hip scores were collected pre-and postoperatively for each patient. The sporting and physical activities of all patients were pre-and post-operatively recorded.

The mean age of patients at surgery was 54 yrs and 56 yrs at review. The mean follow up time was 19 months. Following surgery there was a significant improvement in UCLA activity level scores from 4.4 to 6.8 (Wilcoxon Matched-pairs Signed rank test, p< 0.05). Oxford hip scores significantly improved from 43.4 to 17.7 following surgery. Eighty six patients regularly participated in sport before they became symptomatic with significant hip pain, and 75 regularly participated in sports after surgery. In total 87% of patients successfully returned to their regular sporting and physical activities following surgery. Many patients were returning to high impact sports including football, tennis, cricket and squash.

The published medium-term survivorship of the Birmingham hip has given surgeons increasing confidence to use the prosthesis on a younger generation of patients. Our study has demonstrated that hip resurfacing can allow patients to remain extremely active.

We aim to identify any changes in the demographics of ACL injured patients over the last decade. Over a twelve month period, the demographic data from 117 consecutive new patients with ACL injuries attending one consultant’s clinic in 1994 was prospectively recorded. This was then compared with data from a similar cohort of 103 consecutive new ACL injured patients attending the same clinic some twelve years later.

Since 1994, the proportion of women seen with ACL injury doubled from 12% to 25%. The proportion of skiing related injuries trebled from 9% to 28%. The average age at presentation rose by 6.5 years from 26.5 to 33. In 2006, the average age of the skiers was 40 and 72.4% of them were female compared to only 8% of non-skiers.

The population of patients with new ACL injuries has changed significantly over the last twelve years. The average age, proportion of women and number of skiing related injuries have all increased significantly. We speculate that the most likely cause of these changes is the skiing population, which has enlarged and, due to retention of participants, has aged over the period of this study (1). Most skiing injuries are sustained abroad and the vast majority of skiers buy holiday insurance to cover themselves against injury. Yet it is the NHS that ends up footing the bill for any reconstructive surgery and rehabilitation. We propose that if the insurance companies maintained responsibility for their clients’ injuries until a full recovery had been made, the NHS would save millions of pounds.

The details of 320 consecutive patients undergoing knee microfracture, with a minimum follow up of 6 months, were taken from the Sports Injury Database at the Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry. All had same phsyiotherapy regime post operatively. Two rounds of postal questionnaires were administered to assess patient satisfaction along with Lysholm, Tegner, VAS for pain and a modified IKDC scores. 196 patients responded (61.25%).

The mean age of our patients was 40.64 years and the mean follow up 37.02 months (range 6–78 months). There were 35 smokers and 161 non-smokers. 64 patients had surgery in the medial compartment, 35 in lateral, 50 in patella-femoral and 47 belonged to the combined category. 93 patients had other surgeries (partial meniscectomies, ACL reconstruction etc) along with microfracture(47.45%).

Seventy two percent of patients were satisfied with their outcome and 18.95% weren’t. 51.43% of smokers were satisfied with their outcome and 76.88% of non smokers (p=0.021). Patients more than 50 years of age were less satisfied (p=0.023) than younger patients. Having concomitant knee surgery, including ACL reconstruction, made no difference to patient satisfaction or functional scores.

The location of the lesion in the knee did not affect patient satisfaction. However, all five post op score levels were statistically different among them. The Lysholm post op scores were significantly better in lateral and PFJ compartments than medial. Lateral and combined groups were significantly better than medial for Tegner post op scores. Lateral and PFJ groups were significantly better than medial for VAS and modified IKDC scores.

Smoking and age significantly affect patient satisfaction after knee microfracture. Having concomitant knee surgeries doesn’t make a difference to either satisfaction or functional outcome. Our results suggest that the medial compartment doesn’t do as well in functional scores as previously thought.

The aim of this study was to investigate the function, limitations and disability of a large cohort of active golfers following total knee replacement (TKR). The study group comprised the membership of the New Knee Golf Society (NKGS) and 211 members were reviewed with a questionnaire which asked the patient’s experience & difficulties of playing golf before and after TKR.

The functional outcome was recorded using the Oxford knee score. A total of 299 knees (TKR only) in 209 patients were included in the final analysis. The mean age was 70 years. Majority of the prostheses were cemented (95%) and had patellar resurfacing (90%). The mean post-operative period was 5 years. We found 196 patients (94%) returned to playing golf after a mean of 4.6 months following the TKR; 184 (88%) continue to play at review; 93% claimed significant improvement in their capability to play golf following TKR. However, none claimed to have achieved a significant improvement in their handicap.

Seventeen knees (5.7%) underwent revision surgery. Six knees (2%) were revised for infection at mean 17.3 months and eleven (3.7%) for aseptic loosening or instability at mean 5 years. Seven left knees (lead knee) of eleven right-handed golfers required revision for aseptic loosening. Varus collapse of the tibial component in the lead knee was observed.

The main problems experienced after playing 18 holes were knee stiffness (47%) and swelling (18%). Oxford Knee Scores: 69% excellent; 27% moderate functional impairment; 4% poor outcomes.

Although the capability to play improved the handicap remained the same. We found that the left TKR in a right-handed active golfer is more likely to require revision, which may be due to the increased torque on the lead knee.

We present a retrospective study of a consecutive cohort of 109 patients, under the age of 60, who had either a patello-femoral replacement (PFR), uni-compartmental replacement (UKR) or a total knee replacement (TKR). They were operated on by 2 senior surgeons between 2002 and 2006 at the Avon Orthopaedic Centre in Bristol. The aim of this study was to look at the effect of knee replacement on the employment status of this group of patients.

Data were collected from patient’s hospital records and a questionnaire regarding occupational status sent postoperatively to patients. Statistical analysis showed that our groups were similar which meant that further comparison between them was valid.

Eighty two percent of patients who were working prior to surgery and who had either a TKR or UKR were able to return to work postoperatively. Only 54% of those who had a PFR were able to return to work and this was statistically significant when compared with patients in the other two groups p=0.047. The median time for return to work postoperatively for the study population was 12 weeks. Those in the PFR group took significantly longer to do so (20 weeks) compared to those who had either a UKR (11 weeks) or TKR (12 weeks) p=0.01. Patient’s subjective opinion as to their ability to work following knee arthroplasty was worse in the PFR group p=0.049.

This is the first study to compare employment status following patello-femoral, uni-compartmental knee and Total Knee Replacement. TKR and UKR are effective in returning patients to active employment and that this is typically 3 months following surgery. Patients who had a PFR did not experience the same benefits in terms of numbers returning to work, time to do so and their subjective opinion as to their ability to cope with normal duties.

In Scotland, the number of primary total knee replacements (TKRs) performed annually has been steadily increasing. Data from the Scottish Arthroplasty Project has recently demonstrated that the number of knee replacements performed annually has now outstripped the number of hip replacements. The price of the implant is fixed but the length of hospital stay (LOHS) is variable. An understanding of what currently influences LOHS may therefore be of paramount importance in order that we can influence some of these parameters, with resulting benefit to our patients as well as contributing significantly and favourably towards the health economics of this procedure. This study investigates the influence of intra- and post-operative variables on LOHS.

All patients who underwent primary unilateral TKR in the region of Fife, Scotland, United Kingdom, during the period December 1994 to February 2007 were prospectively investigated. The following intra and postoperative details were recorded: length of operation, need for urinary catheterisation, patella resurfacing, lateral release, blood transfusion, the presence of superficial or deep infection, day 1 post-operative haemoglobin and haemoglobin drop (haemoglobin drop between admission haemoglobin and day 1 post-operative haemoglobin). The data was analysed using univariate and multiple linear regression statistical analysis.

Data on LOHS was available from a total of 2105 primary unilateral TKRs. The median LOHS was 8.0 days. The highly significant intra and post-operative factors associated with an increased LOHS were lateral release, post-operative haemoglobin, blood transfusion, urinary catheterisation, deep and superficial infection. An awareness and understanding of these factors may enable us to influence them favourably with resulting reduction in the LOHS and, therefore, the associated costs.

Orthopaedic surgeons vary in their surgical approaches to total knee arthroplasty. The aim of this investigation was to compare outcomes after two different surgical approaches. The study was a prospective single-centre longitudinal randomized controlled trial. A sub-vastus approach was compared with a medial para-patellar approach. Participating surgeons elected to randomize their patients to one of the two types of approach. Outcomes included the Knee Society (KS) Clinical Rating System, WOMAC Osteoarthritis Index, SF-36, and EuroQol (measured at 1, 6, 12 and 52 weeks post-operatively compared to baseline) complications, surgeon rated ease of exposure, and proportion of patients who had a lateral release.

Two hundred and thirty one patients were randomized to the two approaches. One hundred and sixteen patients were randomized to the sub-vastus approach. At one week compared to baseline, range of motion, KS global, KS knee, and KS pain scores were significantly better in the sub-vastus group. At six weeks, the medial para-patellar group tended to have better outcomes, but not statistically significantly. At fifty-two weeks compared to baseline, the WOMAC global and pain scores, the SF36 physical function and role-physical scores, and the EuroQol utility and pain score were significantly better in the sub-vastus group. Surgeons reported the ease of exposure in the sub-vastus group was significantly worse on average.

This trial is the largest of its kind to date, and the first, so far as we are aware, to compare clinical outcomes of different surgical approaches at one year post-operatively. The sub-vastus approach to total knee arthroplasty was more effective than a medial para-patellar approach at both one week and fifty-two weeks post-operatively in patients whose surgeons considered either approach would be suitable. However, surgeons reported worse ease of exposure in the sub-vastus group.

We aim to create a set of reference data of commonly used scoring systems in the normal population, and to compare these results with published postoperative scores for commonly performed knee operations. This was a questionnaire-based study and a total of 744 questionnaires were sent out, of which 494 replies were received. Six scoring systems were addressed: Lysholm and Oxford Knee Scores, Tegner and UCLA activity scales and Visual Analogue Scales (VAS) for both pain and function. Data was collected into groups based on age (20–29, 30–39, 40–49, 50–59, 60–69, 70–79, 80–89 years). The reference data obtained was then compared to published postoperative scores for knee arthroplasty and ACL reconstruction, to assess whether these patients did indeed return to “normal”.

The mean scores for sequential age groups (described above) were as follows: Oxford Knee Score – 13, 13, 14, 14, 17, 15, 17; Lysholm Knee Score – 96, 95, 92, 89, 89, 89, 79; Tegener Activity Scale – 6, 5, 5, 4, 4, 3, 3; UCLA Activity Scale – 8, 7, 7, 7, 6, 6, 5; VAS pain – 5, 8, 10, 9, 14, 12, 20; VAS function 96, 95, 90, 90, 86, 84, 84. Symptom based scoring systems (Oxford Knee Score, Lysholm) were independent of age whereas activity scores (Tegner, UCLA) decreased with age. There was no significant difference detected between scores in different sexes in the same age group. Compared to published scores in an age-matched population following TKR, the data obtained showed that patients do not return to normal scores following arthroplasty. Following ACL reconstructive surgery, activity scores were higher than compared to the data obtained from our population.

Data generated from this study can be used as reference data and can play an important role in interpreting post-intervention scores following knee surgery.

The medium term results of the JRI Furlong Total hip replacement have been very impressive to date. We report the longest prospective series to date of a hydroxyapatite coated femoral prosthesis (Joint Replacement Instrumentation limited, London, UK) at 15–21 years follow up. We describe the long term clinical and radiological femoral stem survival of 331 consecutive JRI Furlong Hydroxyapatite coated total hip replacements in 291 patients at an average follow-up of 17.5 years (15 – 21 year). Two patients (0.6%) were lost to follow-up over the 21 years of the study period. Using revision of the femoral stem for any reason as an endpoint, we report a stem survival of 97.4 % (81.0 to 99.5). Using Aseptic loosening as an endpoint, stem survival was 100%.

The average Merle, D’Aubine & Postel scores recorded for the patients was 5.63/6 for Pain, 5.42/6 for mobility and 4.50/6 for function. There were no cases of anterior thigh pain relating to the uncemented femoral stem.

These results compare favourably with the best long term survival of cemented or uncemented femoral stems used in total hip replacements.

Infection in total knee replacement is a devastating complication. Current literature supports two-stage revision as the gold standard treatment. The alternative single stage procedure has been reported to have favourable results. We assessed the early clinical results of single stage revision for infected total knee replacement.

Between February 2005 and August 2007, 12 patients had revision total knee replacement for infection by the senior authors at two centres. In the majority of the patients, the infective organism was isolated by arthroscopic synovial biopsy prior to revision. Standard single stage procedure included the explantation, debridement and re-implantation of the prosthesis. All the patients received intravenous antibiotics for six weeks and oral antibiotics were continued for further 6 weeks. All the patients had the inflammatory markers monitored during follow-up.

Significant improvement was noted in the SF-12 PCS, WOMAC pain and stiffness scores at the latest follow-up. None of these patients required re-revision. Radiological evaluation was done using the Knee Society system. None of the knees showed evidence of progressive loosening. Radio-opaque lines were found around the stems and were present on immediate post-operative radiographs; this did not indicate loosening or infection at a mean follow-up of two years.

Early clinical and radiological results of the single stage revision for infected total knee replacement appear to be promising. One operation, one anaesthetic and quicker recovery are the advantages for the patient and with the reduced hospital stay it is cost-effective. The problems of stiffness in the knee and muscle wasting with cement spacer are avoided.

Femoral stress shielding in cementless THA is a potential complication commonly observed in distally loading press-fit stems. This prospective study describes long-term femoral bone remodeling in cementless THA at a mean of 17 years (range: 15 to 20) in 208 consecutive fully HA-coated stems (Corail, DePuy Int. Ltd, Leeds, UK).

All THA were performed by one group of surgeons between 1986 and 1991. The concept of surgical technique included impaction of metaphyseal bone utilizing bland femoral broaches until primary stability was achieved without distal press-fit. Radiographic evaluation revealed a total of five (2.4%) stems with periprosthetic osteolysis, which were associated with eccentric polyethylene wear. They were either revised or awaiting revision surgery. The remaining 97.6% stems revealed biologic load transfer in the metaphysis alone (52%) or in both metaphysis and diaphysis (48%).

Stem survival of 97.6% after 15 to 20 years without stress shielding were considered to be related to: impaction of metaphyseal bone, bland broaches, HA coating, and unique prosthetic design.

A recent meta-analysis for total knee replacement (TKR) undertaken with navigation demonstrated improved accuracy of implant positioning but did not have sufficient evidence on functional outcomes. This meta-analysis evaluates the functional outcomes for TKR with and without navigation.

We present a randomized prospective and comparative studies on functional outcomes of TKR with and without navigation were identified. The selected articles were tested for publication bias and heterogeneity. Studies presenting the functional outcomes in terms of knee society score, oxford knee score and HSS scores were included in the study. The data was then aggregated by random-effects modelling after which estimated weighted mean differences for individual functional scores were calculated.

Sixty two studies were identified and reviewed independently by two researchers; ten studies fulfilled the inclusion criteria, resulting in 976 cases for the meta-analysis (490 with navigation and 486 without). The mean age of both groups was similar (68 and 69). Results of a meta-analysis are best demonstrated by funnel graphs, forest plot, P values, and confidence intervals. In summary, the weighted mean of difference of KSS score is −0.288, with a p value of 0.867. Moreover, the standard means of difference of Oxford knee score was 0.133, with a P value of 0.257. The HSS scores resulted in a SMD of −0.099 and a ‘p’ value of 0.686. Finally, the range of motion weighted means of difference was 1.428, and a ‘p’ value of 0.228.

This meta-analysis demonstrated that there is no statistical advantage to the use of navigation for TKR in terms of functional outcome; the increased positional accuracy does not impart an improved outcome as has been proposed. This is probably due to the tolerances available in the implant positioning. This meta-analysis is providing the early outcomes & highlighting the necessity of long term studies.

The principles of revision total knee replacement are to understand the cause of failure, adequate surgical exposure, achieving appropriate soft tissue balance, restoration of limb and joint line alignment, correct implant alignment, and a good range of motion. It is a technically and economically demanding procedure and its successful performance requires thorough preoperative planning, adherence to the principles, availability of diverse implant options and adequate bone graft.

We prospectively assessed the survivorship of Co-ordinate Ultra prosthesis (DePuy, Warsaw, Ind) used for revision knee arthroplasty. Forty-nine patients had 53 revision knee replacements performed by the senior author between April 1999 and September 2001. Seven patients (7 knees) had died. At a mean follow-up of 6 years (range: 5–7 years), 46 knees in 42 patients were available for review. None were lost to follow-up. There were 31 women and 11 men, with a mean age of 74.2 years. The reason for revision was instability in 39 knees, infection in 3 knees, pain in 2 knees and stiffness in 2 knees.

Significant improvement was noted in the SF-12 PCS and WOMAC pain and stiffness scores at the latest follow-up. None of these patients required re-revision. None of the knees showed evidence of progressive loosening. Radio-opaque lines were found around the stems and were present in immediate post-operative radiographs; this did not indicate loosening or infection on further follow-up. Cumulative survival analysis (Kaplan-Meier method) was 100% at 7 years.

Clinical and radiological outcome analysis has revealed that the Co-ordinate Ultra revision knee system continues to function satisfactorily at a mean follow-up of 6 years.

Complex primary total knee replacements have been poorly reported in the literature We review all complex primary total knee replacement procedures at Stepping Hill Hospital. Patients underwent knee examination, knee scores, notes review and pre- and post-operative radiograph review. There were 29 patients with 36 knees that had a complex primary total knee replacement. Most frequent indications for surgery were osteoarthritis, rheumatoid arthritis or following trauma. Mean age at surgery 70 years. The prosthesis used were : 3 Stryker Kinemax; 32 De Puy PFC and one rotating hinge. Complex Primary Oxford knee score; preoperative mean 45 (range 33 to 57); postoperative mean 26 (range 14 to 53). NJR Total Knee Replacement Oxford knee score postoperative mean 30. Mean visual analogue scores; pain in the knee, mean 19; knee function, mean 77; outcome of the operation 76; satisfaction with the surgery 87. Mean length of hospital stay 13 days.

Using the Knee Society Radiographic Scoring System, there were no signs that need to be monitored or signify failure. Seven patients were transfused postoperatively, four patients had minor wound problems, three required further surgery, two to washout the knee and exchange the polyethylene liner, one femoral plating to stabilise an osteotomy site. Long term complications : one above knee amputation for infection, one foot drop.

Revision implants can be used in complex primary knee replacements, and pose technical difficulties but address various pathologies. The surgery is associated with an increased risk of complications and transfusion. Clinical scores at least match scores for routine total knee replacements, patient satisfaction is excellent.

Providing a long-lasting total hip arthroplasty for patients younger than 50 years remains one of the greatest challenges for modern arthroplasty surgery. Survival has been considered to be poor in young and active patients. We evaluated the benefit of total osteointegration of the prosthetic components in term of durable biological fixation.

This study concerns a prospective series of 113 patients operated between 1986 and 1994. The femoral component (Corail, Landos-DePuy) and the acetabular shells (Atoll & Tropic, Landos-Depuy) were totaly coated with a 150μ thick layer of pure HA following a plasma-spray process. The mean age at the time of surgery was 40.3 (range 17 to 49.8). Two patients are now deceased, 11 patients (9.7%) are lost to FU. The mean FU for 100 patients still on file is 14 years. AVN represents 29 % of the cohort, primary arthritis 22% and dysplasia 17%.

Functional results are excellent (mean PMA score 17.7 at the last control), as well as the subjective appreciation from the patients (94.9 % excellent or very good). 18 THA’s required components revisions: 6 without any implant removal (head or insert exchange); 1 stem (periprosthetic fracture) and 11 cups (6 well-fixed and 5 for loosening) were removed. Owing the high incidence of wear-related revision, actuarial survivorship, using re-operation for any reason as end-point, was 82% at 18 years ± 8.5, and considering aseptic loosening only, the survival probability of the stem is 99% ± 1.5 and 97 % ± 3.5.

It is clear that HA-coatings have given lesser performance in the cups than in the stems. We advocate for HA and the eradication of wear debris using hard on hard bearings. This combination seems to be a reasonable solution in this subgroup of young patients.

Previously ankylosed or surgically arthrodesed hip joints can be converted successfully to a total hip replacement (THR) in order to improve patient mobility and function. We present a long term prospective cohort study of cementless revisions of previously ankylosed hips.

Sixteen hips (15 patients) with a mean age of 52 years (range 16 to 75) had ankylosed hips for a mean of 36 years (range 3.5 to 65 years). They all received a cementless THR between August 1988 and January 2003 and were prospectively followed-up for a mean of 11 years (range 5.0 to 19 years). Two patients died during the study period of unrelated causes and none were lost to follow-up.

All patients showed improved mobility and function following the conversion of their ankylosed hips. The Harris Hip Score improved from a pre-operative mean value of 70 (Standard Error of Mean (SEM) 3.4) to a post-operative value of 83 (SEM 4.4) at the latest review, which was statistically significant (p < 0.05).

There was one acetabular cup revision at 5 years post implantation for aseptic loosening. At a mean of 11 years post THR, all other femoral and acetabular components remained clinically and radiographically well fixed. One patient with systemic ankylosing spondylitis and spontaneous bilateral bony hip ankylosis developed the unusual complication of Paget’s disease of the left hemipelvis and proximal femur two years after successful bilateral THR surgery. His symptoms resolved following medical therapy for Paget’s disease.

We conclude that a previously ankylosed hip can be effectively converted to a cementless total hip replacement with good long term results.

A prospective study of displaced femoral neck fractures was conducted, using the Corail® stem, a non cemented HA-coated device, provided with a bipolar head. 293 consecutive patients were included. Our reasons to shift to an uncemented implant were:

the existence of intraoperative deaths during cementation;

Follow-up was extended up to 5 years, unless the patient died before. 7 patients were lost from FU. Function was assessed every year using various clinical scores (Parker’s mobility score, Qureshi’s mental status, Jensen’s autonomy index,). An X-Ray was obtained at each visit when possible, with a special insistence at completion of the follow up (136 out of the 144 still alive patients).

Intraoperatively, 11 isolated calcar cracks and 1 fracture of the major trochanter were seen. In three cases, it was impossible to obtain a stable implantation. In two of these, a cemented implant was used. In the third patient, instability was not seen, leading to an 8 mm subsidence, along with thigh pain and distal hypertrophy of the femur. The 278 other patients had no intra-operative complications.

Late complications were:

1) 14 patients had a secondary subsidence of their device (1–4 mm), with a subsequent good stability and unaltered fixation to the skeletal tissue;

Juvenile idiopathic arthritis (JIA) affecting the hip can cause debilitating pain and walking disability in children. Total hip replacement offers the potential of a pain free joint and a significant improvement in function. There remains the concern regarding the high rates of aseptic loosening of cemented total hip replacements in this group of patients, and there is evidence that younger patients have higher failure rates.

The aim of this study was to look at the results of uncemented total hip replacement in children with Juvenile Idiopathic Arthritis and in particular to assess any problems associated with performing this surgery in the presence of open growth plates in the acetabular and trochanteric regions.

Between 1995 and 2005, 56 uncemented total hip replacements were carried out in 37 children with JIA with a mean follow up of 7.5 years (range 3 to 12.5). 25 of the hips had ceramic on ceramic bearings. The mean age at surgery was 13.9 years (range 11–16). 19 patients underwent bilateral procedures. All patients showed a significant improvement in their HSS Hip scores (p< 0.01). Two CAD CAM femoral stems were revised for gross subsidence and three acetabular components were revised for loosening. Four polyethylene liners were exchanged due to wear. 51 of 53 (96%) femoral stems and 50 (94%) acetabular components remain well fixed at latest follow up with no signs of loosening. There were no dislocations or infections.

Uncemented fixation appears to work well in this challenging group of patients even in the presence of open growth plates. Implant choice is important to avoid problems of subsidence and loosening. Ceramic bearings available for small implant sizes give promise of improved performance compared to polyethylene over the long term.

Bio-active fixation has increasingly gained acceptance over the last two decades. However extent of the coating is still a subject of debate. We introduced in 1986, the concept of total osteointegration of a tapered stem with the hope that we could achieve durable biological fixation while preserving normal periprosthetic bone trophicity.

Patients from our first clinical series using this stem are now eligible for 18-year follow up. Between July 1986 and December 1990, we performed 615 THA using the Corail stem (DePuy). Corail is a straight tapered stem totally coated with a 150 μthick layer of HA following an atmospheric plasma-spray process. The mean age at surgery was 64.5 (range 16 to 95). 242 patients are now deceased (39%), 62 patients (10%) are lost to follow-up. The mean follow-up for 243 living patients on file is 17.7 years.

Eighty nine THA’s required component revisions: 72 cups, 9 stems, 8 “cups and stems”. 8 cups and 4 stems have been revised for aseptic loosening. Owing to the high incidence of wear-related revision, Kaplan-Meïer survivorship at 18-year follow-up, using component revision for any reason as an endpoint, was 80.7 ± 3.3 (95% confidence intervals). In contrast, Corail stem survivorship, using stem removal for any reason as an endpoint, was 95.0% ± 3.0 at 18-year follow-up, and considering aseptic loosening only, the survival probability of the stem is 98.9% ± 1.1 at 18 years.

Therefore, despite wear and proximal osteolysis, the fixation achieved with this totally HA-coated stem remained durable through 18-year follow-up. Regarding the periprosthetic remodelling during this period, modifications of the bone pattern have been strictly limited: slight resorption at the calcar level, absence of cortical hypertrophy, anecdotic significant stress-shielding. The radiological silence is one of the paramount facts demonstrated by this prospective study.

We aim to report the clinical, radiological outcome of consecutive primary hip arthroplasties using the JRI-Furlong Hydroxyapatite ceramic coated acetabular components. We reviewed 412 consecutive primary THA using fully coated acetabular shell in 392 patients, with minimum 12-year follow-up to 18 years, performed at two institutions. Twenty (22 THA) were lost prior to 12-year follow-up, leaving 372 patients (390 THA) available for study.

Fully HAC coated stems were used in all patients. Clinical outcome was measured using Harris, Charnley Oxford, EuroQol EQ-5D scores. Radiographs were systematically analysed for implant position, loosening, migration, osteolysis. Polythene wear was digitally measured.

Mean age was 74.4 yrs. Dislocation occurred in 10 patients (3 recurrent). Revision operations were performed in nine patients (1.9%). Four acetabular revisions were performed for aseptic loosening. Other re-operations were for infection (3), periprosthetic fractures (1), cup malposition (1), revision of worn liner (3). The mean Harris and Oxford scores were 87 (78–97) and 19.1 (12–33) respectively. The Charnley score was 5.6 (5–6) for pain, 5.2 (4–6) for movement and 5.3 (4–6) for mobility. Migration of acetabular component was seen in 4 hips. Acetabular radiolucencies were present in 54 hips (9.7%). The mean linear polythene wear was 0.06mm/year. Mean inclination was 48.4 deg(38–65). Mean EQ-5D description scores and health thermometer scores were 0.81 (0.71–0.89) and 86 (64–95). With an end point of definite or probable loosening, the probability of survival at 12 years was 96.1%. Overall survival at 12 years with removal or repeat revision of either component for any reason as the end point was 94.2%.

The results of this study support the continued use of a fully coated prosthesis and documents the durability of the HAC coated components. In our clinical experience, the Furlong prosthesis revealed encouraging radiographic stability over a long term period

Decompression of the lumber spine for spinal stenosis is the most commonly performed spinal surgical procedure in patients over 60 years old. The aims of surgery are to relieve compression of the spinal nerves and retain integrity of the structural elements of the spinal column and its function as a supportive structure. In trying to avoid excessive removal of the posterior supportive structures of the spinal column without compromising full and safe decompression of the spinal nerves, techniques are being developed to reduce bone removal but also allow access to the spinal canal.

One such micro-decompression involves a hemi-laminectomy and lateral recess decompression on the more symptomatic side followed by undercutting the spinous processes and decompressing the opposite side from within the canal aided by the use the operating microscope, a high speed burr and a copper moldable retractor to protect the dura and nerves.

We have reviewed our first 100 consecutive patients who have had a spinal micro-decompression over a period of 5 years. 58 Female and 42 male patients are included in this series. Mean age was 65 years. Patients were assessed by a combination of clinical review and self-assessment questionnaires. After a follow-up period of up to five years (mean 3.5 years) we have seen symptomatic late instability develop in four patients requiring a further surgical procedure in two of these. Symptoms typically developed two years after the original operation following an initial improvement in radicular symptoms and back pain.

This compares favourably with published results for wide decompression where re-operation rates of 18% are reported. We have analysed the cases of delayed instability in more detail to evaluate whether the late deterioration could have been predicted.

Micro-decompression is shown to be safe with few complications and has advantages over wide decompression without compromising safety.

Total hip-joint arthroplasty is associated with a high rate of perioperative blood transfusion, which increases the risk of blood-borne disease, anaphylactic and haemolytic reactions. Devices are used which collect and allow the re-infusion of blood lost during surgery, with the aim of reducing allogenic blood transfusion requirements. The purpose of this study was to establish whether the use of a ‘cell-saver’ device reduces the risk of post-operative allogenic blood transfusion in total hip joint arthroplasty.

All total hip arthroplasties performed by a single surgeon over a twelve month period were divided into two cohorts of patients; one which used an intra-operative cell saver device, the other which did not. Data was collected for patient demographics, pre-operative blood tests and blood loss, with the outcome measure as post-operative transfusion requirements. The total number of patients was 233; 166 primaries, 33 resurfacing & 20 revision arthroplasties: 14 excluded for insufficient data.

Comparison of the two cohorts (intra-operative cell saver used vs. no cell-saver used), demonstrated no significant difference in the post operative blood transfusion requirements for patients undergoing primary total hip joint arthroplasty (n=166, 18.3% vs. 11.0%, p=0.08), Birmingham resurfacing arthroplasty (n=33, 5% vs. 7.7%, p=0.49), and revision arthroplasty (n=20, 28.6% vs. 50%, p=0.26). There were no significant differences demonstrated between the patient demographics of the two cohorts for any of the groups. In the cell-saver cohort, the average volume of blood re-transfused was 117mls per patient (range 0 – 400mls).

Intra-operative use of cell-saver devices does not decrease post-operative transfusion requirements in primary hip arthroplasty. A larger size study is required to assess the outcome in resurfacing and revision hip arthroplasty surgery.

Patients admitted with spinal injuries following trauma require careful serial examinations to detect any neurological deficit that may develop. Thorough documentation of the findings is of paramount importance. Enforced working practice within the NHS means that these patients are often assessed by different members of staff with varying levels of experience, thus inconsistent documentation can be a cause for concern.

The project aim was to design a human computer interface to standardise the performance and documentation of serial neurological examinations in patients with spinal injury, allowing the user to accurately detect any neurological deterioration.

A prototype system was developed for ward based PC’s incorporating the essential requirements of the neurological examination. Usability testing was performed on the prototype by recruiting fifteen users who would be expected to routinely perform the neurological examination on spinal injury patients. Usability was defined by a number of well defined goals (impression, efficiency, learnability, memorability, safety and effectiveness) and methods used in the evaluation included direct observation during completion of tasks, a questionnaire and unstructured interview.

Both quantitative and qualitative data was collected. This data was subsequently analysed using descriptive and inferential methods. The results of the analysis showed that the users responded favourably to the prototype in respects to the all usability goals except efficiency. This lack of efficiency was expected due to the rigid nature of computer based systems compared to paper based methods of recording data but this disadvantage was more than compensated for by the increased patient safety that the system would provide.

It can be concluded from the usability testing that the prototype achieves the aims of the project but further work is required in developing the prototype into a final interface design before beta testing in a clinical environment can be considered.

Backpain is a common cause of patient referral to pain clinics. Around 120 000 patients with back pain are seen in UK Pain Clinics every year. Facet joint injections are a commonly used treatment modality. However there is considerable controversy regarding their efficacy. Most of the evidence supporting the use of injections is anecdotal, rather than being based on randomised studies.

We carried out a prospective study to assess the efficacy of facet joint injections in relieving chronic low back pain. Our study group comprised 41 patients (57% females, 43% males). Patients completed the Oswestry Disability Index (ODI) and marked their pain levels on a Visual Analogue Scale (1 to 10).

We found that though the pain score improved from 6.9 to 4.3, there was only a marginal improvement in the ODI from 52.5 to 50.8. Overall 85 % of patients experienced some improvement, while 15% felt their symptoms had worsened after the injections. One of the most significant findings of this study was the fact that the improvement in most patients lasted only for an average of three weeks. This is significantly less than most previous studies indicate. Interestingly, inspite of this limited improvement, almost all patients expressed the desire to be placed back on the list for repeat injections.

Our study demonstrated a beneficial short term effect of facet joint injections. In our opinion, they are a reasonable adjunct to non operative treatment of chronic backpain.

The SF 36 questionnaire has been validated and used in multiple studies. However, it remains unclear how well patients complete the SF-36 questionnaire in a spinal outpatient clinic setting outside the context of a study. We aim to assess the quality of information gained if the SF 36 is used as an audit and outcome measure in real clinical practice.

The SF 36 has been used in our clinic as a routine for the initial assessment and outcome audit of patients for the last 4 years. A prospective, consecutive sample of 85 patients’ SF-36 forms was evaluated during a spinal out-patient clinic over one month at our teaching hospital. Completeness of data entry was assessed. All patients had access to a translator and clinic nurse to help complete the questionnaire if needed.

There were 34 males and 51 females (age range 16 to 81, average 48). Thirty seven patients were White British, 22 other and 26 undisclosed ethnicities. Thirty eight (45%) forms were complete leaving 47 (55%) which had at least one question unanswered or spoiled. Of these, two had five to ten errors, one had 10 to 15 errors, four had 15 to 20 errors, seven had 20 to 25 errors, ten had 25 to 30 errors and 17 had 30 to 35 errors. In addition six forms were entirely incomplete beyond patient identifier information. White British patients had fewer errors (average 4) compared to other (9) and unknown (9) ethnicities.

Outside the context of a research study, the SF-36 questionnaire in an urban teaching hospital spinal outpatient clinic is not a reliable tool. Redesign of the questionnaire may be required. The SF-36 questionnaire is less well completed by patients declared as non White British, even with the facility for a clinic nurse and a translator.

Spinal pathologies requiring spinal/neurospinal unit’s input/opinion from tertiary centres for their management are initially admitted to DGHs. The referral is made by mailing radiographs with clinical details to the on-call registrar who gets back with a management plan. This arrangement is fraught with delays at various levels having an impact on patient care, financial and medico-legal implications. We discuss these issues between index DGH (Poole General Hospital) and its tertiary referral centres.

To review the existing management of spinal injury admissions at our hospital, analyse critical/adverse incidents and to identify areas for improving patient care.

A comprehensive retrospective review of all spinal admissions/referrals made to tertiary centres over 6 months was undertaken. Twenty eight of the 64 admissions warranted referrals. A structured proforma was used to document the time of admission, time of booking and performing scans, time of referral & response from tertiary centre and time of transfer from hospital notes and delays at each level were critically analysed.

Seven of the 28 referrals had either neurodeficit or spinal instability. Common issues were delay in obtaining CT/MRI scans (av 2.5 days), delay due to reporting/failing to act on results (av 1.8 days), delays due to missing/lost in transit’ scans (av 1.5 day), delay in obtaining opinion (av 4 days) and non-availability of bed for transfer (av 5.5 days). There was 1 mortality and 5 other complications while awaiting transfer. The financial costs incurred were approximately £73,000 & loss of 246 patient-days.

Training on induction day, implementation of spinal care pathway and diligent documentation/communication coupled with succinct referral were strictly enforced following this study. The website www.neurorefer.co.uk was set up by Wessex neurological centre to streamline referrals and enhance efficiency. This website has now grown into a national secure referral portal incorporating other referral centres.

We investigated the hypothesis that autologous bone marrow stromal cells (BMSC) sprayed on the surface of acetabular cups would improve bone formation and bone implant contact.

Total hip replacements were implanted in 11 sheep, randomly assigned to receive either acetabular implants sprayed with autologous BMSCs suspended in fibrin (study group) or fibrin only (control group). Sheep were sacrificed after six months and the acetabulum with the implant was retrieved and prepared for undcalcified histology. Implant bone contact in both groups was compared, by microscopically noting the presence or absence of new bone or fibrous tissue along the implant at 35 consecutive points (every 1000 μm). The observers undertaking the histological analysis were blinded.

Significantly increased bone implant contact was noted in the BMSC treated group 30.71% ± 2.95 compared to the control group 5.14% ± 1.67 (p = 0.014). The mean thickness of fibrous tissue in contact with the implant was greater at the periphery 887.21mm ± 158.89 and the dome 902.45mm ± 80.67 of the implant in the control group compared to the BMSC treated group (327.49mm ± 20.38 at the periphery and 739.1 mm ±173.72 at the centre). Conversely direct bone contact with the implant surface was significantly greater around the cups with stem cells.

BMSC sprayed on surface of implants improves bone implant contact. Spraying acetabular cups using stem cells could be used in humans where acetabular bone contact is compromised such as in revision procedures.

Sectioned femoral components retrieved from failed hip resurfacing arthroplasties show resorption of proximal femoral bone or formation of a fibrous membrane at the bone cement interface. Our study uses Finite Element Analysis (FEA) to examine the effects of the implant orientation on bone remodelling following hip resurfacing arthroplasty. A radiographic analysis of the proximal femur following hip resurfacing was conducted in order to draw a comparison to the FEA findings.

A 3D FEA model of the Birmingham Hip Resurfacing (BHR) was created based on the geometry and material properties of a 45 year-old female donor hip. Hip joint and muscle loads were applied. Bone remodelling stimuli was determined using changes in strain energy. A range of implant orientations were compared to study the affect on bone remodelling. A retrospective radiological analysis was undertaken on 100 hips with a minimum of 5 years follow up. Femoral neck diameter was measured at post-op, 2 and 5 years, as well as neck and stem shaft angles.

FEA showed that valgus orientation was associated with increased resorption underneath the shell. Varus orientation showed increased bone formation at the stem tip. The radiological analysis identified 2 distinct patterns of neck thinning. Slow thinners (76%) had < 5% reduction in neck diameter at 2 years and < 10% at 5 years. Rapid thinner (24%) had > 5% thinning at 2 years and > 10% at 5 years. The mean percentage reduction in neck diameter was significantly different between the two groups at the two time points (p< 0.01). The rapid group had a higher proportion of valgus aligned implants (88%) and a significant decrease in reconstructed offset (p=0.0023).

The FEA results have shown that stem alignment can affect bone resorption resurfacing. FEA results were consistent with the radiological findings. Additional retrieval studies are necessary to help understand aetiology of implant failures.

Spinal anaesthetic (SA) with intrathecal diamorphine and general anaesthetic (GA) with blocks and/or patient control analgesia (PCA) are commonly used in hip and knee replacement surgery. Drop in blood pressure, feeling light-headed and drowsiness, itching are known early complications respectively. This causes delay in patient mobilization post operatively. Our study examines the use of a local anaesthetic infuser device (LAID) (pain buster pump) for post operative pain relief after total hip or knee replacement surgery.

Forty six patients (25) THRs and (21) TKRs were included in this study. Each were given a LAID which consisted of 0.25% bupivicaine infused at 4ml/hr via an elastometric pump over 48 hours. 100mls of 0.1% bupivicaine with 0.5mg adrenaline was infiltrated locally into the wound at closure. All patients were prescribed regular analgesic as per the multimodal pain regime and an hourly pain score maintained. Rescue opioids were prescribed if pain score crossed 5. Patient satisfaction score was recorded as excellent, some or no pain relief. Eleven patients were given general anaesthetic and 25 patients were given spinal anaesthetic.

26% were able to sit out of bed within 6 hours of surgery and 65% (30 patients) were sitting out by the first post operative day. Average length of stay was 6.15 days, decreased to 4 days for patients mobilised on day zero and compared to eight days prior to this study. 21% had excellent result, 29% had some pain and 6% had poor result. 90% needed oral rescue analgesia within the first 48 hours.

LAID allowed some patients to be mobilised within 6 hours of surgery. The use of LAID helps avoids the need for PCA or diamorphine and hence its associated complications though some amount of oral rescue analgesia was necessary. Patient compliance was satisfactory. The early results are encouraging and further studies are been conducted at our hospital.

The purpose of this study was to assess the effect of human autologous serum on the proliferation and differentiation of MSCs and to analyze the serum growth factor content. Serum was obtained from 8 patients suffering from lower limb long bone fractures requiring surgical intervention.

Serum samples were obtained on admission and the 1st-3rd–5th and 7th postoperative day. During the surgical procedure cancellous bone pieces from the fracture were obtained and MSCs were isolated. Cells were cultured with autologous serum from each sample. The cellular potential for proliferation and osteogenic differentiation was assessed. Fetal calf serum (FCS) was used for comparison. The presence of growth factors in the serum was investigated using commercially available colorimetric assays read on Elisa plate reader. We studied the serum content on Platelet Derived Growth Factor (PDGF), Vascular Endothelial Growth Factor (VEGF) and Insulin-like Growth Factor I (IGF-1).

The maximal upregulation of cellular proliferation and osteogenic differentiation was noted in cells cultured from serum obtained between third and seventh days. Cellular proliferation in comparison to FCS was increased by 32% with the use of serum from admission, 23% with the use of serum of the 1st day and 37% and 42% with the serum from 3rd and 7th days respectively. Serum analysis revealed an increase of 80% of PDGF between the 1st and 3rd postoperative day and 135% from 3rd–7th postoperative day. IGF-1 was increased by 35% between day 1 and 7. VEGF was increased by 120% during the first two postoperative days and a further increase of 190% occurred between days 3 and 7.

Growth factors are released in peripheral circulation and are gradually increased after fracture. MSCs under their influence proliferate faster and up-modulate their osteogenic differentiation. These findings should be considered when using functional assays for tissue regeneration techniques.

The purpose of this study was to assess the clinical outcomes of three different rotator cuff repair techniques and to correlate these results with the integrity of the cuff as determined by ultrasonographic evaluation.

Three cohorts of patients had repair of a symptomatic rotator cuff tear using:

an open technique with Mitek RC Quickanchor double row, one mattress suture per anchor (n = 49);

Standardised patient and examiner determined outcomes were obtained prospectively pre-operatively and at 6 weeks, 3 months and 6 months post-operatively. Ultrasound studies were performed with a validated protocol at 6 months post surgery.

Arthroscopic knotless repair was, on average,14 minutes faster than both open cuff repair (p< 0.001) and arthroscopic knotted repair (p< 0.01).Clinical outcomes were similar with the exception that the arthroscopic groups had, on average, 20% better ASES scores than the open group at 6 months (p< 0.001). The only complication was re-tear, which correlated with tear size (r=0.5, p< 0.001) and operation time (r=0.3, p< 0.001) and occurred more frequently following open repair (39%) compared with arthroscopic knotted (25%) and arthroscopic knotless (16%) repair (p< 0.01). The retear rates of tears > 8cm2 were significantly greater (p< 0.01) when using an open (88%) or arthroscopic knotted (67%) technique compared to the arthroscopic knotless (25%) cohort.

Rotator cuff repair, whether performed via an open or arthroscopic technique resulted in improvements in pain, motion, strength and function. An intact cuff on ultrasound corresponded to better results with regard to supraspinatus strength, patient outcomes and rotator cuff functional ability. Tears > 8cm2 fixed with an arthroscopic knotless technique had better structural outcomes at 6 months.

The five year results of 8187 primary total knee replacements undertaken for osteoarthritis in patients under the age of 55 years are presented. The casese were submitted to the Australian Orthopaedic Association National Joint Replacement Registry in the period 1st September 1999 to 31st December 2006. This represents 6.3% of the 130,377 primary knee replacements recorded by the registry for this period.

The five year cumulative revision rate for patients under the age of 55 years was 8.0% (95% CI: 7.2 to 8.9). We compared the results to outcomes of older patients aged over 70 years at the time of surgery. The younger patients have a significantly higher risk of revision in the first five years (hazard ratio of 2.9; 95% CI= 2.59 to 3.26; p< 0.0001). Gender, mode of fixation, the use of cruciate retention or substitution prostheses or patella resurfacing did not significantly affect the rate of revision in those patients aged 55 years or less. Survival of fixed bearing implants was significantly better than that of mobile bearings. The most common reason for revision in this group was loosening (32.3%).

Total knee replacement in patients under the age of 55 years is associated with a much higher risk of revision in the first five years. A decision to proceed with total knee replacement in this age group should be accompanied by a careful explanation of this significantly increased risk compared to knee replacement in older individuals.

This study evaluates the effect of lower limb post-operative mechanical axis on the long term risk of revision surgery following primary total knee arthroplasty (TKA). The study is relevant because many recent clinical trials have evaluated the optimal surgical technique for accurately aligning components in TKA, despite little evidence that alignment may effect the long-term clinical outcome.

The data used in this study was collected prospectively as part of a randomized control trial comparing the long term survival of cemented versus uncemented TKA. The trial included 501 press-fit condylar posterior cruciate ligament-retaining prostheses performed by the senior author (PJG) or under his direct supervision. The post-operative mechanical axis alignment of the lower limb was measured following TKA using standard AP weight-bearing long leg alignment radiographs. A comparison was made between a well-aligned group with a mechanical axis alignment within 3° of neutral; and a poorly-aligned group whose mechanical axis alignment deviated greater than 3° from neutral. Survival analysis used revision surgery, with exchange of any of the three originally inserted components (femoral, tibial, polyethylene insert), as the endpoint.

There was no loss to follow-up in this study. The minimum follow-up of TKAs in this study was 5.8 years. In the population of TKAs that were followed up at 10 years, 6% (17/270) required revision surgery. There was a significant difference in the rate of revision surgery between the well-aligned group 5% (11/227) and the poorly-aligned group 14% (6/43 p< 0.05)

This study shows that post-operative lower limb mechanical axis alignment is an important determinant of the need for revision surgery at 10 years. Surgeons performing TKA should pay particular attention to the placement of the tibial and femoral components, so that a mechanical axis within 3° of neutral is achieved.

Surgeon’s ability to anticipate the implant size requirements for total knee replacements is important to the success of the procedure. Previously, this has been inconsistently accomplished using plain radiographs. The purpose of this study is to assess the accuracy of digital templating software in predicting the size requirements of the femoral and tibial implants in total knee replacements.

Thirty consecutive PFC (DePuy) total knee replacements were templated preoperatively using digital templating software (TraumaCad, Orthocrat Ltd). The knees were templated by two surgeons working independently using standardised digital AP and lateral radiographs. All films were magnification-calibrated using markers of known size. Postoperatively, the predicted implant size was compared to the actual components selected at the time of surgery.

The size of the femoral prosthesis was accurately selected on the AP view in 53.5% and on the lateral in 66% of cases. The size of the tibial implant was correctly selected on the AP view in 65.5% and on the lateral in 70.5% of cases. The tibial prosthesis was always templated within one size. The femoral prosthesis was predicted within two sizes (93% on AP + 98% on lateral +/− 1 size). There was no correlation with failure of the software to recognise the metal marker and inadequate lateral x-rays.

The lateral x-ray was found to be more reliable than the AP on predicting both the femoral and tibial implants. The tibia was more accurately templated than the femur on average. There was good inter-observer and intra-observer reliability for both prostheses (0.75 – 0.85). Discrepancies in templating may have been due to inaccuracies in placement of the metal marker at the time of x-raying or due to fixed flexion deformities, which may have affected the magnification of the x-ray. Overall, templating using digital software was marginally superior to the standard acetate method.

The results of mobile bearing Oxford unicompartmental knee replacement (UKR) in the lateral compartment have been disappointing (five-year survival: 82%). Therefore, it is recommended that mobile bearings should not be used for lateral UKR. This low survivorship is primarily due to a high dislocation rate. A detailed analysis confirmed the elevated lateral tibial joint line to be a contributory factor to bearing dislocation. A new surgical technique was therefore introduced in which care was taken neither to remove too much bone from the distal femur nor to over tighten the knee and therefore ensure that the tibial joint line was not elevated. Other modifications included use of a domed tibial component.

The aim of this study is to compare the outcome of these iterations: the original series (series I), those with improved surgical technique (series II) and the domed tibial component (series III). The primary outcome measure was bearing dislocation at one year. One year was chosen as all the dislocations in the first series occurred within a year. In the original series (n=53), implanted using a standard open approach, there were six dislocations in the first year, the average flexion 110°, and 95% had no/mild pain on activity. In the second series (n=65), there were 3 dislocations, the average flexion was 117°, and 80% had no/mild pain on activity.

In the third series with the modified technique and a convex domed tibial plateau, there was one dislocation, average flexion was 125° and 94% had no/mild pain on activity. At four years the cumulative primary dislocation rates were 10%, 5% and 0% respectively, and were significantly different (p=0.04).

The improved surgical technique and implant design has reduced dislocation rate to an acceptable level so a mobile bearing can now be recommended for lateral UKR.

About ten years ago we introduced sophisticated instrumentation and an increased range of component sizes for the Oxford unicompartmental knee replacement (UKR) to facilitate a minimally invasive surgical (MIS) approach. The device is now routinely implanted through an incision from the medial pole of the patella to the tibial tuberosity. This has resulted in a more rapid recovery and an improved functional result. As the access to the knee is limited there is a concern that the long term results may be compromised. The aim of this study was to determine the 10 year survival.

A prospective follow up of all Phase 3 minimally invasive Oxford UKR implanted by two senior authors (DWM & CAFD) has been undertaken. So far 1015 UKRs have been implanted for anteromedial osteoarthritis. All patients received a cemented implant through a MIS approach and were followed up prospectively by an independent observer. The data was collected prospectively regarding pre-operative status, complications and clinical as well as functional outcome at predetermined intervals.

The average age of patients was 66.4 years (range: 33 – 88) with mean Oxford Knee Score 41 (SD: 7.9) at the time of last follow up, Knee Society Score (objective) of 84 (SD: 13) and Knee Society Score (functional) of 83 (SD: 21). At ten years the survival of this cohort is 96%. There were 22 revisions including 7 for progression of arthritis, 5 for infection, 5 for bearing dislocation, 4 for unexplained pain and one for rupture of ACL secondary to trauma.

We conclude that the Oxford Knee can be implanted reliably through a minimally invasive approach, giving excellent long term results.

We aim to define the role of pelvic fractures (PFx) due to falls, in auditing Trauma Care. We present a retrospective case-control study, based on autopsy. Univariate analysis was used to identify factors predicting mortality and a backward stepwise logistic regression multivariate analysis determined relationships.

Of 970 patients who sustained a fatal fall, 209 (21.5%) constituted the PFx-group, and the remaining 761 the control-group. The PFx-group had a median age of 55 years (15–96), while the control 66 years (1–99). The multivariate analysis revealed that gender, age, intention, and height of fall were risk factors for PFx after a fall. An approximately 300% higher odds of suffering a psychiatric history was found in the PFx-group, (p< 0.001).

The median ISS of the PFx-group was 50(17–75), and was significant higher than the 26(1–75) of the control-group, (p< 0.0001). The “potentially-preventable” deaths (ISS< 75) constituted 78%, while the “non-preventable” 22%.

The most common AIS 3–5 injuries in the “potentially-preventable” deaths were located in the: lower extremities 133(81.6%), thorax 130(79.7%), abdominal and pelvic contents 99(60.7%), head 95(58.3%) and the spine 26(15.9%) of the patients. A subset of 126 (60.3%) “potentially-preventable” deaths of the PFx-group had at least one AIS-90 code other than the PFx denoting major hemorrhage. Deaths directly attributed to pelvic fractures were limited to 6 (2.9%).

The post-traumatic median survival-time for the PFx-group was 30 minutes, while for the control group 20 hours and 15 min. For one group increment in the range of ISS-groups, the probability of post-traumatic survival rate was reduced by 57% (p< 0.0001). Multiplicity, severity and the short posttraumatic survival time in the PFx group render PFx an index-injury for audit of polytrauma.

A reproducible method of autopsy-data analysis was outlined. Pelvic fracture is a paradigm of injury that selected an index-population among 970 fatal falls and an appropriate basis to construct a template for evaluation of trauma & polytrauma care.

This study was aimed to develop a non-invasive technique to analyse motion of the patella during the gait cycle. Ten subjects with no history of patello-femoral pain syndrome or evidence of patella mal-tracking on clinical examination were individually assessed on 160 dynamic walking trials. Retro-reflective markers were attached to the proximal, distal, medial and lateral poles of the patella and the position of the patella relative to the centre of the knee joint was tracked and recorded during their gait cycle using a nine camera (120Hz) ViconTM infra-red motion analysis system.

We found that there was more medial-lateral motion (shift) of the patella than proximal-distal (tilt) motion during the gait cycle. It was noted that the patellar shift motion occurred in the swing phase or the early stance phase of the gait cycle of all subjects with the maximum patellar shift occurring when the knee was flexed between 30–56 degrees in the majority of subjects. Similarly the patellar tilt motion occurred in the swing phase or the early stance phase of the gait cycle with the maximum patellar tilt occurring between 20–36 degrees of knee flexion in the majority of subjects.

These results indicate that normally the maximum amount of patellar shift and tilt occurs in the swing and early stance phases of the gait cycle and that abnormal patellar motion can be detected if excessive shift or tilt occurs outside of these phases. From the findings of the current study, it is proposed that future studies are needed to quantify patellar motion during walking. The future work should be directed to assess patellar motion during swing phase and early stance phase of the gait cycle using more sophisticated techniques like dynamic magnetic resonance imaging to exactly quantify patellar motion.

Systems for collecting information about patient care are increasingly common in orthopaedic practice. Databases can allow various comparisons to be made over time. Significant decisions regarding service delivery and clinical practice may be made based on their results.

We set out to determine the number of cases needed for comparison of Thirty-day mortality, inpatient wound infection rates and mean hospital length of stay, with a power of 80% for the demonstration of an effect at a significance level of p< 0.05. We analysed two years of prospectively collected data on 1,050 hip fracture patients admitted to a city teaching hospital. Power calculations were performed using standard equations from the literature.

Detection of a 10% difference in 30 day mortality would require 14,065 patients in each arm of any comparison, demonstration of a 50% difference would require 643 patients in each arm; For wound infections, demonstration of a 10% difference in incidence would require 23,921 patients in each arm and 1127 patients for demonstration of a 50% difference; For length of stay, a difference of 10% would require 1,479 patients and 6660 patients for a 50% difference.

Our data helps to illustrate the importance of sample size when interpreting the results of performance monitoring. Since a unit as large as our own only admits 525 patients per year, comparisons between trusts would require very prolonged data collection. Within a single unit the demonstration of poor performance by one surgeon or one team would clearly be impossible. Statistically meaningful analyses will only be possible with major multi-centre collaborations, as will be possible if hospital Trusts participate in the National Hip Fracture Database.

Clopidogrel, an anti-platelet agent is used in the secondary prevention of ischaemic events in high risk patients. Recent studies suggest that there are no National guidelines on when to stop clopidogrel in patients with hip fracture. It is suggested that stopping clopidogrel and waiting up to 1 week or more before surgery may have adverse effects on the patient.

This study is aimed at identifying factors predicting outcome in these patients. All patients admitted to our unit in 2006 with proximal femoral fracture were included. Patients on clopidogrel were identified for further investigation. Demographic, perioperative and postoperative data including complications and death were documented.

Thirty one of 586 patients with proximal femoral fracture were on clopidogrel on admission. Mean delay to surgery was 8.4 days (range 2–16 days SD 2.5). The mean age was 81 years (64–97) with a male to female ratio of 1:2.4. Of the 31 patients, 8 (25.8%) had died at 1 year. The standardised mortality ratio was higher in patients less than 65 years old and lower in all patients over 65 years.

Significant predictors of death on univariate analysis at one year were spinal anaesthesia (p = 0.04), postoperative blood transfusion (p = 0.03), postoperative complication (p = 0.03) and delay to surgery (p = 0.03). There was a positive correlation between delay to surgery and developing a postoperative complication (Pearson’s correlation 0.33 p = 0.04). Multivariate analysis revealed that delay to surgery was the only independent factor predicting death at one year.

No evidence exists to suggest that clopidogrel should be stopped 1 week prior to surgery for proximal femoral fracture. Waiting for 1 week or more prior to surgery is directly correlated to developing postoperative complications and subsequent death at one year.

RECORD3 was a multicentre, phase III study designed to investigate the efficacy and safety of rivaroxaban – a novel, oral, once-daily, direct Factor Xa inhibitor – compared with subcutaneous enoxaparin for thromboprophylaxis in patients undergoing total knee arthroplasty (TKA).

Patients scheduled to undergo TKA (N=2,531) were randomized to receive either rivaroxaban 10 mg once daily (initiated 6–8 hours after surgery) or enoxaparin 40 mg once daily (initiated the evening before surgery, then given 6–8 hours after surgery), and daily thereafter for 10–14 days.

The primary efficacy outcome was the composite of any deep vein thrombosis (DVT; symptomatic or asymptomatic detected by mandatory, bilateral venography), non-fatal pulmonary embolism (PE) and all-cause mortality within 13–17 days after surgery.

Rivaroxaban significantly reduced the incidence of the primary efficacy outcome compared with enoxaparin (9.6% vs 18.9%, respectively; p< 0.001; relative risk reduction [RRR] 49%). Rivaroxaban significantly reduced the incidence of major VTE (the composite of proximal DVT, non-fatal PE and VTE-related death) compared with enoxaparin (1.0% vs 2.6%, p=0.01; RRR 62%), and the incidence of symptomatic VTE (0.7% vs 2.0%, p=0.005; RRR 66%). The incidence of bleeding events was similar in both groups (major bleeding: 0.6% and 0.5% in the rivaroxaban and enoxaparin groups, respectively; any on-treatment bleeding: 4.9% and 4.8%, respectively; haemorrhagic wound complications [the composite of excessive wound haematoma and surgical-site bleeding]: 2.0% and 1.9%, respectively). There were no deaths or PEs in the rivaroxaban group during the treatment period, and two deaths and four PEs in the enoxaparin group.

Rivaroxaban was significantly more effective than enoxaparin for the prevention of VTE after TKA, with a similar rate of bleeding. The oral, direct Factor Xa inhibitor rivaroxaban, given once daily as a fixed, unmonitored dose of 10 mg, has the potential to change clinical practice for thromboprophylaxis after TKA.

Echocardiograms are requested in patients presenting with hip fractures and the finding of a cardiac murmur. The opinion amongst anaesthetists in our department is that general anaesthetic (GA) is safer in patients with significant aortic stenosis, mitral regurgitation, or left ventricular impairment compared to spinal anaesthetic (SA).

A retrospective review was carried out and data on fifty patients were collected, who had presented with fractured neck of femur with the finding of a heart murmur and required an echocardiogram pre-operatively.

Our results demonstrated :

Focussed history and examination was rarely performed;

Our audit suggests that many echocardiograms are ordered unnecessarily. Effective use of clinical skills and investigations are rarely utilised by orthopaedic doctors, in requesting an echocardiogram. There is delayed operating times, cost implications and increased workload for the cardiology department. There is no indication that the results of these echocardiograms significantly influences anaesthetic choice.

A second audit cycle was performed prospectively with the use of a proforma. An echocardiogram was not ordered if a recent echocardiogram (within last the last year) was normal or if the history, examination and ECG findings in a patient were all insignificant. This demonstrated a reduction in ordering of echocardiograms by 40%. Local guidelines have been implemented in our department.

The first United Kingdom In-training Examination (UKITE) was held in 19 training programmes during December 2007. The aims of the project are to offer a national, online examination (providing immediate results to trainees) and to allow practice for the ‘real’ FRCS T& O examination with similarly formatted questions based on the UK T& O curriculum. All Speciality training years (StR2, StR3 and above, and all SpRs) and all deaneries will participate in the future. A total of 450 trainees sat this first examination. This is an online exam (accessed through the eLogbook/OCAP website) which is voluntary and has no bearing on RITA outcomes. To take part in the exam trainees were asked to provide 3 questions for a bank which can be used in subsequent years for both UKITE and the FRCS T& O examination.

The exam was 3 hours and questions were of multi-choice (MCQ) and extended matching question (EMQ) style covering all aspects of orthopaedics. Correct answers and explanations were available to the trainee after their answer had been submitted. Final scores ranged from 35% to 92%. Mean scores increased from 48% (StR2) to 73% in SpR year 5 (StR7 equivalent). This was followed by a drop off in performance in the final year of training. Three candidates had equal top scores at 92%. 97% stated they would sit the UKITE again and 93% felt there was educational benefit. The length and level of difficulty of the exam was felt to be satisfactory. Improvements were suggested for question quality. The UKITE is a powerful tool for self-assessment of trainees. This analysis establishes a baseline for future years.

In the current climate of increasing financial pressures and reducing bed numbers, a predictor of length of stay (LOS) may have a bearing on hospital finances. Independent sector treatment centres may also skew the ASA grade and co-morbidity of the patient group treated in a hospital setting. We performed a study of 100 consecutive patients undergoing Total hip or knee arthroplasty between April and September 2006.

Median age was 71 years (35 – 88) with 75% of patients having significant (cardiac, renal or respiratory) pre-existing medical conditions (24% with 3 or more conditions). Average ASA grade was 2 (15% grade 3) and average BMI was 30. A significant reduction in LOS from 8.47 to 5.87 days was seen in under 70 year olds when compared with those over 70 years (p = 0.0004), having 3 or more co-morbidities (compared with 2 or less) increased average LOS from 6.61 days to 9.3 days (p = 0.002), ASA grade of 3 increased LOS to 9.56 days from 6.27 and 6.87 for grade 1 and 2 respectively (p = 0.014) and living alone (compared with cohabiting) increased LOS from 6.55 days to 9.19 days (p = 0.0017). However no statistical significance was seen for BMI with an average of 7.19 days for < 30 and 7.37 days for patients with BMI of 30 or above (p = 0.82)

Regardless of this patient group being elderly and obese with significant co-morbidity, an acceptable outcome was seen, with 70% of patients discharged within 7 days and only 4% staying > 14 days. Although BMI did not predict outcome, number of co-morbidities, ASA, age greater than 70 years and living alone all demonstrated a significant increase in LOS. Increased resources in this at risk group within a pre-admission setting could reduce length of hospital stay.

Gentamicin is one of the most widely used antibiotics in Orthopaedic practice. It is commonly used as prophylaxis either through intravenous route, incorporated into bone cement or topical intraoperative irrigation. The former two are well studied. However, there is limited study on the therapeutic efficacy and safety of topical Gentamicin irrigation.

To assess the safety and infection rate of joint replacement surgery when topical gentamicin irrigation was used. This is a non-randomised, prospective study whereby patients undergoing joint replacement surgery were treated with gentamicin irrigation intra-operatively.

A total of 138 patients were divided into two groups in this study. Group A (98 patients) were patients with Total Joint Replacement and group B (40 patients) were patients with hemi arthroplasty of the hips and shoulders. Patients with pre-existing renal impairment were excluded. Two ampoules of Gentamicin (160mg) were irrigated into the wound before implants insertion and wound closure respectively. Intravenous Cefuroxime was also given prophylactically to all patients but none of them had intravenous gentamicin. Plasma Gentamicin level was assayed 4 hours and 24 hours post-operatively.

There were 16 patients in group A (16%; p< 0.001) and 12 patients in group B (30%; p< 0.001)) found to have plasma Gentamicin level > 2mcg/ml. All but 6 had plasma gentamicin level dropped to < 2mcg/ml at 24 hours. Although none of them developed systemic complications, the raise in plasma gentamicin was alarming. The incidence of infection was 6.1% (6 patients) in group A. These were superficial wound infection responded to antibiotics. No infection was reported in group B.

This study did not show apparent reduction in infection rate as compared to the reported literatures. Nevertheless, there was significant systemic absorption of topical gentamicin irrigation. Therefore, monitoring of post-operative plasma gentamicin levels is mandatory to avoid unforseen toxicity.

We performed a prospective audit to investigate the comparability of subjective and objective assessment scores of shoulder function following surgery for rotator cuff pathology. A consecutive series of 372 patients underwent surgery for rotator cuff disorders with post-operative follow up over 24 months. 248 patients solely underwent subacromial decompression, whereas 124 had additional rotator cuff repair (93 arthroscopic; 31 open).

Assessments were made pre-operatively, and at 3, 6, 12, and 24 post-operative months using the Disabilities of the Arm, Shoulder, and Hand (DASH) score; Oxford Shoulder Questionnaire (OSQ); and the Constant score, which was used as a reference. Standardisation calculations were performed to convert all scores into a 0 to 100 scale, with 100 representing a normal shoulder. The student’s t-test was used to compare the mean score for each subjective tool (DASH and OSQ) with the objective score (Constant) at each time point. Correlation coefficients (Pearson’s) were used to analyse the changes with time (post-operative course). Each statistical test was used for all surgeries collectively and for the individual surgery types.

The relationship between the DASH and the Constant score was robust in all types of surgery. The relationship between the Oxford and Constant was generally robust, except in the open rotator cuff group. There was no statistical difference between the mean DASH and Constant scores for all interventions at each time point. A significant difference was seen between the mean Oxford and Constant scores for at least one time point in all but the open rotator cuff repair group.

We demonstrate the DASH and Oxford scoring systems would be useful substitutes for the Constant score, obviating the need for the trained investigator and specialist equipment required to perform the Constant score, alongside the associated cost benefits. Further it provides evidence of service, aids appraisal and revalidation.

An online survey has been carried out to evaluate the compliance with the OCAP learning tools, and the availability of clinical experience to early years’ trainees in Trauma and Orthopaedics in 2007–8. Three surveys were planned over the year, and we present the results from the first two surveys. Over the initial eight month period, 335 trainees in Trauma and Orthopaedic posts responded. There was considerable variation in the proportion of responses from different deaneries, and it was felt this reflected differences in the use of the two logbooks available (FHI or ISCP).

Respondents were FTSTAs (50%), ST1s (11%) and ST2s (29%). The respondents reported their operative experience was poor with low numbers of index procedures – the median values being 2 DHS, 1 Hemiarthroplasty and 0 for Ankle ORIFs performed as the lead surgeon in the first 4 months, rising to 3, 1 and 1 respectively in the second. As an assistant the numbers were 3, 4 and 3. FTSTAs had done more procedures as lead surgeon. It is not clear whether this reflects motivation, or whether they are trainees who were unable to secure training posts due to seniority and were already more experienced. Many posts were entirely ward based.

Improvements in meetings with Assigned Educational Supervisors were noted, as was the use of the learning agreements, and with registration rates with the ISCP. There was considerable variation between posts, hospitals and deaneries, and a tool was developed to summarise this data to be post-, trainee-, and duration-specific. Summaries of each post were distributed to Training Program Directors, Heads of School, and the SAC. Although some improvement has occurred, further rounds of the survey are necessary to ensure that this continues. The next round will commence in September 2008 to complete twelve months of data.

MRI was used to diagnose occult hip pathology in patients with a clinically suspected femoral neck fracture where no abnormality was detected on plain x-ray. All patients admitted into our unit with post traumatic hip pain, an inability to weight bear, and no abnormality found on a series of plain radiographs, underwent an MRI scan of the pelvis and affected hip to look for an occult femoral neck fracture.

The study included 102 consecutive patients who were prospectively studied over a 10 year period between 1997 and 2007. Four patients were excluded due to contraindications or an inability to tolerate having an MRI scan. Of the remaining 98 patients 81 had abnormalities detected (83%). 42 of these patients had evidence of a proximal femoral fracture. 23 patients underwent an operative procedure.

Eight incomplete intertrochanteric fractures were treated non-operatively with good results. One patient had a primary diagnosis of malignancy made on the basis of the MRI scan. One patient had a known primary malignancy but this was the first diagnosis of bony metastatic disease. Seventy five patients were scanned within 48 hours of admission (average 2.4 days).

The use of MRI in our unit was felt to be appropriate in patients with a high suspicion of proximal femoral fracture. Our results show that there is a significant incidence of fractures that are not apparent on plain x-rays. MRI led to early diagnosis and initiation of definitive management, potentially reducing cost and complications of immobility. It was most useful in showing the extent of the fracture, and picked up on other occult pathologies of the hip and pelvis. We recommend stabilisation of femoral neck fractures and non operative management of all incomplete intertrochanteric fractures if able to non weight bear. There must be a high index of suspicion of undiagnosed malignancy

We aimed to audit the results of one stop fragility fracture risk assessment service at fracture clinic for non-hip fractures in 50–75 years old patients at Newcastle General Hospital. Currently, fewer than 30% of patients with fragility fractures benefit from secondary prevention in the form of comprehensive risk assessment and bone protection because of multifactorial reasons. We have a fragility fracture risk assessment service staffed by an Osteoporosis Specialist Nurse equipped with a DEXA scanner located at the fracture clinic itself.

We carried out a retrospective audit of 349 patients of 50–75 years with suspected non-hip fractures referred from A& E Department from October 2006 to September 2007. Patients over 75 years were excluded because as per NICE guidelines, they should receive bone protection without need of a DEXA scan.

Out of these 349 patients with suspected fractures, 171 had fragility fractures. Median age was 64 years. 69 patients had humerus fracture, 65 had forearm fracture and 23 patients had ankle fracture and 14 had metatarsal fractures. Fracture risk assessment was carried out in 120 (70%) patients. Thirty Seven (31%) patients had osteoporosis and bone protection was recommended to GP. 38 (32%) had osteopenia and lifestyle advice was provided. 45 (37%) had normal axial bone densitometry. 90% patients had DEXA scan at the same time of fracture clinic appointment. Patients with male gender, undisplaced fracture and fewer fracture clinic appointments were more likely to miss fracture risk assessment.

Our experience suggests that locating fragility fracture risk assessment service co-ordinated by an Osteoporosis Specialist Nurse at fracture clinic is an efficient way of providing secondary prevention for patients with fragility fractures. This can improve team communication, eliminate delay and improve patient compliance because of ‘One Stop Shop’ service at the time of fracture clinic appointment.

There is continuing debate regarding the merits of internal fixation versus arthroplasty for intracapsular hip fractures. For displaced fractures there is a higher risk of fracture healing complications but many of the studies reporting on this are now from some years ago using surgical methods that are now outdated. The aim of our study was to determine the incidence of avascular necrosis (AVN) related to age, gender, displacement and operation delay for a large series of patients with intra-capsular fractures treated with internal fixation using contemporary methods.

We prospectively studied 1023 patients, 988 fractures were internally fixed with three cannulated screws and 35 with a sliding hip screw. The average length of radiographic follow-up for those patients who survived to one year was 337 days (range 25 to 3521 days). The average age of the patients was 75.4 years (range 16–100); 243 (23.8%) were male. The overall incidence of AVN was 6.6%. AVN was less common (p=0.0004) for undisplaced fractures than for displaced fractures (21 of 528 [4.0%] vs 47 of 495 [9.5%]) and in men than women (p=0.03) who had a displaced fracture (7 of 143 [4.9%] vs 40 of 352 [11.4%]). The incidence of AVN for those aged less than 60 years and who sustained a displaced fracture was 20.6%, compared to 12.5% for those aged 60–80 years and 2.5% for those aged more than 80 years (p< 0.0001). We found no association between the incidence of AVN and operation delay.

Our study showed an increased risk of AVN with younger age and in females with a displaced fracture. This is in contrast to the decreased incidence of non-union seen with younger age. Knowledge of the predicted incidence of fracture healing complications should help surgeons make a more balanced decision between internal fixation and arthroplasty for this condition.

In order to assess the effect of osteoporosis on healing time we retrospectively reviewed the files of 165 patients with femoral shaft fractures that were treated in our service by locked, intramedullary nailing. Patients were divided in two age groups; Group A (study group) consisted of patients over 65 years old with radiological evidence of osteoporosis and group B (control group) of patients between 18 and 40 years old with no signs of osteoporosis.

Sixty-six out of 165 patients fulfilled the inclusion criteria for this study. Patients with open fractures, pathological fractures, revision surgery, severe brain injuries, prolonged ITU stay and severe co morbidities were excluded. Twenty-nine patients were classified in group A and 37 in group B. All patients had been assigned the Injury Severity Score (ISS) and had been followed-up clinically and radiographically until fracture union.

In all patients the Singh Index Score for osteoporosis was assigned. In all group A patients Singh score 4 or less was assigned, suggesting the presence of installed osteoporosis, whereas group B patients were assigned with Sighn score 5 or 6. Fracture healing was significantly different between the groups.

Fractures of Group A healed in 19.38±5.9 weeks (12–30) and in group B 16.19±5.07 weeks (10–28) (P=0.02) Fracture healing of nailed femoral diaphyseal fractures significantly delays in older osteoporotic patients. Further studies are mandatory to clarify the exact impact of osteoporosis in the whole healing process and the possible future therapeutic strategies.

400 patients with a trochanteric hip fracture were randomised to fixation with either a 220mm long Targon PF (proximal femoral) nail or a Sliding Hip Screw. All surgery was undertaken or supervised by one surgeon. All patients were followed up for a minimum of one year by a blinded observer.

The mean age was 82 years (range 27 to 104 years), 20% were male. Mean length of surgery was slightly increased for the nail (44 versus 49 minutes, p=0.002). Fluoroscopic screening time was increased in the nail group (0.3 versus 0.6 minutes, p< 0.0001). Intra-operative complications were more common with the nailing. There was no difference in blood transfusion requirement between groups. Postoperatively there was no difference in the occurrence of medical complications or mortality.

Deep wound infection requiring removal of the implant occurred in one case in the SHS group. In addition there were two cases of cut-out, three of plate detachment from the femur and one non-union in the SHS group, requiring secondary surgery. There were only once compilations in the nailed a case of cut-out which required secondary surgery. At follow-up there was no difference in pain scores between groups but there was a tendency to improved mobility in the nailed group (p=0.004).

These results suggest that with improved designs and surgical technique, the newer versions of short nails for proximal femoral fractures may not suffer from the complications of the earlier short intramedullary nails. Intramedullary fixation can result in a lower re-operation rate (3.5% versus 0.5%) and improved mobility in comparison to the sliding hip screw.

Hip fractures are a significant cause of mortality and morbidity in the elderly. Malnutrition is a major element of this but no consensus exists as to the detection or management of this condition. Reported incidence in elderly hip fracture patients varies widely between 9.0% and 88.6%.

The aim of this study was to evaluate the nutritional status of 415 patients with operatively managed hip fractures and determine the prognostic relevance of admission serum albumin and total lymphocyte count (TLC) assays. Protein-energy malnutrition (PEM) was defined as serum albumin < 3.5g/dl and a TLC < 1,500 cells/mm3. Delay to operation, duration of in-patient stay, re-admission (< 3 months) and in-patient, 3- and 12-month mortality were assessed as outcome variables.

Survival data was available for 377 patients at 12 months. Of 377 patients, 53% (n=200) had both a serum albumin and TLC levels taken at admission, while 47% (n=177) had not. The incidence of PEM was 51%. Inhospital mortality for PEM patients was 9.8%, compared with 0% for patients with normal values of both laboratory parameters. Older patients were more likely to have lower albumin (p=0.017) and TLC (p=0.023). Nursing home patients were also more likely to have lower albumin (p=0.033). Multivariate analysis revealed a significant difference in 12-month mortality, with patients who had both a low albumin and a low TLC 4.6 times (95% CI: 1.0–21.3) more likely to die within 12 months postoperatively than patients who had normal values of both laboratory parameters. This was significant after adjusting for age, gender and domicile (p=0.049).

Serum albumin and TLC in combination are accurate predictors of 12-month mortality in hip fracture patients. These results highlight the relevance of assessing the nutritional status of patients with hip fractures at the time of admission and emphasises the relationship between nutrition and outcome.

Primary pyomyositis is increasing in incidence in the western world. Although a commonly encountered condition in the tropics it was not described in the USA until 1971 and the UK until 1998. The reason for the increasing incidence is not understood.

Typically pyomyositis affects the muscles around the hip and may present in a variety of ways to orthopaedic or general surgeons – occasionally leading to unnecessary operative intervention. We sought to identify the experience gained, of this condition, within a UK paediatric tertiary referral unit.

A retrospective review of cases of pyomyositis, from our institution, since 1998 was undertaken to identify demographics, presentation, diagnosis and management. Thirteen cases of pyomyositis were identified. Obturator internus was most commonly affected (n = 7). Trauma was implicated in three cases and group A staphylococcus was cultured in nine cases. Male:Female ratio ~ 3: 2. Initial working diagnosis at presentation was septic joint in eight cases, appendicitis in three cases and soft tissue abscess in two cases. Ten cases settled with antibiotics alone. One diagnostic retroperitoneal exploration was performed which may have been avoided with greater preoperative awareness of this condition. On reflection, all cases were identified by CT or MRI.

To our knowledge, this is the first UK series of pyomyositis, reflecting its increasing incidence in the western world. Its presentation is similar to other common paediatric surgical emergencies, yet its management is very different – often not requiring surgery. A greater awareness of this emerging condition is therefore essential to both general and orthopaedic surgeons in order to prevent misdiagnosis and unnecessary surgical intervention.

Dislocation is a major concern following THR for fractured neck of femur. The aim of this prospective study was to investigate the use of large diameter femoral head uncemented THR to treat fractured neck of femur, and to demonstrate if the improved stability seen in previous clinical situations with these designs, can be used to benefit this difficult subgroup of patients that are particularly prone to dislocation.

Forty-six consecutive independent, active and mentally alert patients with displaced intracapsular fractured neck of femur underwent large diameter head uncemented THR. The mean age of patients was 72.1 years. The outcome measures used were the dislocation rate, reoperation and revision rate, Oxford hip score (OHS), EuroQol (EQ-5D) and residential status.

Clinical and radiological data were available on all 46 patients. At a mean follow-up of 12.5 months there were no dislocations. There were no reoperations, revisions or infections. Two patients died (4.3%) from unrelated causes. Mean pre- and postoperative OHS were 12.1 and 17.9 respectively. The mean pre- and postoperative EQ-5D index scores were 0.97 and 0.83 respectively. The mean postoperative walking distance was 2.5 miles and there were no changes in residential status.

This is the first published series utilising a 36-mm diameter metal-on-metal THR for the treatment of fractured neck of femur in mobile, independent patients. We have demonstrated that it affords patients excellent stability with no recorded dislocations.

As part of the workup long length femur radiograph may be carried out pre-operatively in patients presenting with a proximal femur fracture in order to rule out distant metastasis in patients with a history of malignancy but also in some patients in whom a suspicion of possible distal abnormality is aroused by the configuration of the proximal fracture

Using our unit’s database we identified all patients (n=689) presenting with a proximal femoral fracture between Sept 2006 and August 2007 at the Norfolk and Norwich University hospital in Norwich.

Of 689 patients, 92 patients (13.2%) had long length femur radiograph performed before surgery. Indications included history of cancer (39), subtrochantric fractures (14), spontaneous fracture without any fall(2), paget s disease(1), early onset osteoporosis(1) while no clear indication was available in 35 patients. Five patients (5.5%) were found to have some abnormality. Three of the 39 patients with a history of previous cancer were found to have a distal femur metastasis. Two of the 35 patients where a clear indication was not apparent had abnormal findings: one patient had a distal femur infarction and another was found to have a distal femoral malunion. In both cases long leg films did not influence choice of implant. Of the 39 patients with a previous history of cancer, 24 had short implants (hemi-arthroplasty, intramedullary device, DHS), 14 had long implants and one patient died before the operation.

Long length femoral radiographs appear to be indicated in patients with a documented history of a cancer as it helps to decide whether to use a long or short implant. However in patients without a history of malignancy, long leg films were of no value in decision making even if the configuration of the fracture was suspicious.

Non-bacterial osteitis (NBO), a term referring to sterile bone lesions with non-specific histopathological features of inflammation, may be either uni- or multifocal, acute (6 months) or chronic, and recurrent. Only when the condition is chronic, recurrent and multifocal is it appropriate to use the term chronic recurrent multifocal osteomyelitis (CRMO).

We present our clinical experience as the largest reported series of children with NBO to date. Of 41 children (2–16 years) diagnosed with NBO in our institution over the last 6 years, 21 (51%) had recurrent disease and 18 of 41 (44%) had multifocal disease. The most common bones affected were the clavicle, femur and tibia (in order of decreasing prevalence) accounting for 44 (63%) of a total of 70 lesions. Only one individual had SAPHO syndrome and no other patients had evidence of bowel or skin disease. In the absence of evidence for an infective aetiology, we recommend non-steroidal anti-inflammatory agents as first line therapy, and bisphosphonates only in cases of resistant disease.

On the basis of our findings we propose a patient questionnaire and protocol for investigating and managing patients who present to orthopaedic surgeons with NBO. We predict that this will benefit patients with this disorder by providing valuable information about the pathogenesis, clinical outcome and response to treatment. In the future, clarification of the pathogenesis of this disease will undoubtedly help rationalise the therapeutic approach improving both quality of life and outcome for these patients.

This study aims to determine, by outcome analysis, the appropriateness of current criteria employed to select patients for total hip arthroplasty (THA) as the primary treatment for displaced intracapsular hip fracture (DICHF) and to inform prospective randomised controlled trials investigating the efficacy of THA as a primary treatment.

Contemporary THA eligibility criteria were derived from recent publications relating to pre-fracture residence, mobility and independence. Outcome data were analysed for 96 patients (19% of 506 consecutive patients with DICHF between 2003–2005) who fulfilled those criteria. The variables analysed included age, gender, co-existing injuries, co-morbidities, social circumstances, mobility, independence, delay to surgery, readmission, and death. Patients were followed for three years. The primary outcome was the combined achievement of home or warden-assisted accommodation at three months, no re-admission within 6 weeks and survival to 1 year. Secondary outcome was survival to three years.

At 3-months 86 patients (90%) had returned home, three (3.1%) required nursing or residential home placement, four (4.2%) were still resident in a community hospital, and three (3.1%) had died. Eight patients (8.3%) were re-admitted within 6-weeks. Mortality was 8.3% at 1-year and 25% at 3-years. Patients not achieving return to home were older (84.8 years vs. 79.7 years, p=0.19), were more likely to use a walking aid (OR 2.35) or required home support (OR 1.74) prior to fracture. The number of co-morbidities was not an association. Backward selection identified age as a significant variable in patients successfully discharged home (OR 1.12, CI 1.01 – 1.21).

If maintaining a high level of activity and independence is the expectation for hip fracture patients considered for THA then current selection criteria appear appropriate in identifying those 15% capable of returning home, remaining independent and surviving to one year.

An 11 year prospective longitudinal study assessed the relationship between major neonatal foot deformities and developmental dysplasia of the hip (DDH). From 41,474 infants born between 01/01/1996 and 31/12/2006 with 614 foot deformities were referred as ‘risk factors’ in a screening/surveillance programme for DDH. All hips were clinically examined and sonographically imaged in a specialist Paediatric Orthopaedic clinic.

The 614 cases were subdivided into: 436 postural equinovarus deformities (TEV), 60 fixed congenital talipes equinovarus (CTEV), 93 congenital talipes calcaneovalgus (CTCV) & 25 metatarsus adductus. The overall risk of sonographic dysplasia/instability was as follows: TEV 1:27, CTEV 1:8.6, CTCV 1:5.2, Metatarsus adductus 1:25

The Relative Risk (RR) of sonographic dysplasia/instability in TEV vs CTEV was 0.31 (95% CI 0.12–0.80; p=0.0057; OR=0.29). The Relative Risk of dysplasia/instability in CTCV vs. Postural TEV is 5.27 (95% CI 2.57–10.8; p< 0.0001; OR=6.30).

The risk of Type IV hip instability or irreducible dislocation in CTCV was 1:15.4 (6.5%), 1:25 (4%) in metatarsus adductus and 1:436 (0.2%) in TEV. There were no cases of hip instability (Type IV) or irreducible dislocation in the CTEV cases.

The routine screening for DDH in cases of postural TEV and fixed CTEV is no longer advocated. Postural TEV is poorly defined as a deformity in the literature leading to the over diagnosis of a possibly spurious condition. Sonographic imaging and surveillance of the hips in cases of CTCV and metatarsus adductus should continue.

Universal neonatal screening of developmental dysplasia of the hip (DDH) remains controversial and a few centres have adapted this practice in the United Kingdom. Our institute has established a DDH screening programme over the last 19 years. The following shows our result after a recent change in our screening programme protocol. All infants born in Coventry are screened for DDH by a clinical examination and ultrasound scan (USS). 5,084 babies were born over a 12-months period. Normal examination and USS were detected in over 90% of the cases. Abnormality detected through either clinical examination or USS was referred to a special orthopaedic/USS clinic.

However, in the majority of the cases, subsequent assessments were normal and only 23 babies required treatment. In these cases, the majority had not shown any signs of clinical abnormality. However, serial USS had shown persistent abnormality of at least Graf grade II or higher. The average time from birth to a treatment with a Pavlik Harness was 35 days and the average duration of a treatment was 48 days. Apart from one case, all the babies were treated successfully. The unsuccessful cases had a Graf grade IV at the presentation and had shown no sign of improvement on sequential USS. No complications were noted.

While the sensitivity of detecting DDH through clinical examination remains poor, USS has become an essential tool in our screening programme. Many initial abnormalities are secondary to hip immaturity and they tend to resolve. Those with clinical instability and persistent USS Graf grade II or higher should be treated with early Pavlik Harness. Early detection has led to better results than late diagnosis, and in addition to this, the overall number of operations required could be reduced. Yet, the need for a major surgical intervention has been all but eliminated.

This is a case series of 25 patients with Multiple Epiphyseal Dysplasia (MED), a genetically determined disorder characterised by abnormal ossification of multiple epiphyses. The Nottingham Skeletal Dysplasia Clinic has run since 1966. In 1994 it combined with the Clinical Genetics Service providing care to patients from throughout the region. We collected data on MED patients with follow up of 1 to 41 years (average 12 years) and described their presenting symptoms, genetic, clinical and radiographic features. We followed the natural history and vast array of treatments.

From the genetic point of view, 90% of patients counselled had typical AD-MED and 10% syndromic MED. Seven families opted to have testing. There were MATN3 mutations in 10% of the cohort, with marked intra-familial variability of phenotype. The average age at presentation was thirteen, with 80% of patients presenting before their sixteenth birthday. A third was seen because of a known family history of MED. Newly diagnosed index patients tended to present later. The most commonly affected joint at presentation was the hip and the most common knee deformity genu valgum. Symptoms progressed with time and joints not clinically affected at presentation became symptomatic later. Sixty percent of patients had further joint involvement within 10 years of diagnosis. Treatment ranged from orthotics to arthroplasty. Half of patients required surgical intervention at least once. Six patients underwent hip arthroplasty at an average age of 37.

MED is a rare diagnosis but has significant impact on the quality of life of those diagnosed, who require the support of a multidisciplinary team from an early age. This is not only to help manage symptoms and preserve function, but also to counsel on the progressive nature and the genetic aspects of the disorder.

Treatment of severe Perthes disease remains a major challenge. Various surgical options exist for containment. We describe the Birmingham interlocking triple pelvic osteotomy (BITPO) and report the results at skeletal maturity.

We reviewed 22 hips in 21 consecutive patients with severe Perthes who had the BITPO. There were 16 males and 5 females. The mean age at presentation was 7 years 7 months. Seventeen hips were Herring group C and five were Herring group B. Six patients had four head-at-risk signs (HARS), 9 had three HARS, 4 had two HARS and 3 had a single HARS. The mean age at operation was 8 years 2 Months.

Clinical, radiological and functional evaluations were under taken on these patients who have since reached skeletal maturity. The minimum follow up was 6 years. Average age at review was 18 years 8 months (range 16–25). Two patients have since had hip resurfacing, and two patients a double femoral osteotomy and one patient a surgical dislocation of the hip and valgus osteotomy.

The average Harris Hip Score pre-operatively was 52, which improved to a mean score of 82. Eleven hips were classified as Stulberg I/II (50%), 9 hips Stulberg III/IV (41%) and 2 hips Stulberg V (9%). The average increase in Centre-Edge angle was 31 degrees and there was an average improvement of 24.6% in the head coverage. At follow up the average abduction was 31 degrees (improvement of 8.5 degrees), internal rotation 22 degrees (10.5 degree improvement) and flexion 106 degrees (11 degree improvement).

We conclude that the Birmingham interlocking triple pelvic osteotomy provides excellent coverage of the femoral head in severe Perthes disease, recaptures and remoulds the deformed head and avoids retroversion of socket. Good results in severe Perthes disease are maintained beyond skeletal maturity.

DDH incidence falls from 5–20 per 1000 at birth to 1–2 per 1000 by 3 weeks. Some patients present late and frequently require surgical intervention. If the hip cannot be contained without tension, these children undergo open reduction +/− a femoral shortening, varus and derotation osteotomy. Salter’s osteotomy, may be performed either at index surgery or later in the presence of persisting acetabular dysplasia. Our aim was to see if we could predict which cases of persistent DDH would require both femoral and pelvic surgery to contain the affected hip, using a single plain AP radiograph of the pelvis in the outpatient setting.

We performed a retrospective study of all children older than 18 months with persistent DDH of one or both hips, over the last 5 years, who had undergone femoral and/or pelvic surgery to contain the hip. Plain AP pelvic radiographs were standardised according to the method described by Tonnis. From these radiographs the acetabular indices and child’s age in months, were recorded. Syndromic and children with non-standard x-rays were excluded.

Thirty nine hips (34 female, 5 male), age range of 18–102 months, formed our study group. 53% of hips having femoral surgery later required pelvic surgery for persisting acetabular dysplasia. Examining the data in these cases, the difference between the acetabular index of the normal and affected hip was always greater than 20 degrees and the child’s age in months.

Using this method we conclude that it is possible to predict which cases of persistent DDH will require pelvic surgery to fully contain the affected hip and that this can be done with one AP pelvic radiograph in the outpatient clinic. The benefit is avoidance of unnecessary pelvic osteotomies, and being able to determine the cases which should have a pelvic osteotomy at index procedure.

The management of spasticity of children with cerebral palsy is often complex and challenging. Effective treatment requires a multidisciplinary approach involving paediatricians, orthotists, occupational therapists, physiotherapists and orthopaedic surgeons. Botulinum toxin A therapy in the lower limb has been shown to relieve spasticity and to improve the function in the short term. However, the use of Botulinum toxin A in the upper limb remains controversial, moreover only selected few orthopaedic surgeons have experience in managing it. The aim is to assess the functional improvement following an upper limb Botulinum toxin A injections to the upper limb and then to evaluate the patient’s and parents’ satisfaction after the procedure.

During 2007 a total of 36 spastic cerebral palsy patients underwent 47 episodes of Botulinum toxin A injections to the upper limb. There were 22 male and 14 female with an age range between 2 to 17 years (average age was 2 years). Following the surgery, all patients received a course of an intense exercise regime with the physiotherapist and occupational therapist. All patients were prospectively followed-up by the clinic with no loss to follow-up. We also assessed the functional movement of the patients as well as the patient’s and parents’ subjective evaluation of the procedure.

Overall, the range of movement of the upper limb has improved following the Botulinum toxin A injection. Most patients/parents were satisfied with the procedure and would consider further injection in the future. Botulinum toxin A injection to the upper limb is generally well received with good short term results. Many would consider further injections to sustain improve function.

Salter’s innominate osteotomy predisposes the hip to acetabular retroversion as it hinges upon the symphysis pubis. Retroversion is a recognised cause of osteoarthritis, hip pain and clinical signs of impingement, but there is uncertainty as to whether this over cover persists with growth and development.

We reviewed the long-term follow up of twenty patients that had undergone a Salter’s osteotomy between 1985 to 1993 at The Royal Orthopaedic Hospital Birmingham or New Cross Hospital Wolverhampton. Sixteen skeletally mature patients were available for review that had previously had the pelvic osteotomy performed at a mean five years of age with a contralateral normal hip. Salter’s osteotomy had been performed for developmental dysplasia of the hip in 13 patients and for Perthes’ disease in three patients. Follow up was performed at an average age of 20 years. Outcome was assessed using the Harris Hip Score and a clinical examination for signs of impingement and by a measurement of acetabular version, on well centered pelvic radiograph.

Acetabular version was evaluated by the relationship between anterior and posterior walls of both the normal and Salter acetabulum, using radiographic templates as described by Hefti. Mean acetabular version averaged 16.9 degrees (95% CI 7.6 to 26.1) of anteversion on the Salter side and 17.6 degrees (95% CI 10.4 to 24.8) anteversion on the contralateral normal hip. There was no statistical difference between the version on operated and normal hips, paired t test (p = 0.83). Harris Hip Score averaged 85, indicating a good outcome at long-term follow up. Two patients (12%) demonstrated retroversion, however neither of these had signs of impingement on clinical examination.

After a Salter innominate osteotomy in childhood, we believe there is remodelling of acetabular version by skeletal maturity.

Lateral hip pain is a common problem in middle-aged females. After investigation, a group of patients remain who are given the diagnosis of ‘trochanteric bursitis’. Treatment to date has included physiotherapy, non-steroidal anti inflammatory medication and judicious use of a combined corticosteroid and local anaesthetic preparation injected into the bursa with or without imaging control. Some surgical procedures have been described. The aims of this study are to document and describe our experience with 88 patients and to raise awareness of the condition as a common cause of lateral hip pain which is amenable to surgical repair.

This study has the approval of the Western Sydney area health service. Between 2000 and 2008, 161 patients were referred to the senior author for management of lateral hip pain. 121 patients underwent surgery to repair a gluteal tendon detachment. 32 patients were excluded from the study due to concurrent or previous surgery to the area. A surgical audit was performed on the remaining 88 patients.

Assessment was performed using the Merle d’Aubigne and Postel scoring system. The average duration of symptoms was 6 – 144 months. At 6 months, 88% patients had minimal or no pain. There were also significant improvements in range of motion and ability to walk. The most significant complication was deep vein thrombosis (6%).

Based on our experience, any patient who does not respond to treatment for trochanteric bursitis should be investigated for a gluteal tendon tear. Those with a positive MRI scan of the trochanteric region can be offered surgery for gluteal tendon repair.

We assessed polyethylene wear and osteolysis in 15 patients (30 hips) undergoing staged bilateral total hip arthroplasty, who had a cemented hip arthroplasty on one side and a hybrid arthroplasty on the other. All factors apart from mode of acetabular component fixation were matched. Wear was measured radiographically using Livermore’s technique.

The mean clinical and radiological follow-up was 11.2 years for the cemented arthroplasties and 10.7 years for the hybrid arthroplasties. Mean annual linear wear rate for the cemented cups was 0.09mm/year, and 0.14mm/year for the uncemented cups. This difference was statistically significant (p=0.03), confirming previous reports that polyethylene wear in uncemented cups is greater than in cemented cups. Polyethylene wear in the uncemented cup exceeded wear in the cemented cup by more than > 0.1mm/year in 5 patients, 4 of whom had a BMI of greater than 30.

No periacetabular osteolysis was noted. Femoral osteolysis was present in 5 hybrid arthroplasties and 2 cemented arthroplasties. Zone 7 femoral osteolysis occurred in 3 patients on the side of the hybrid arthroplasty, multifocal femoral osteolysis not involving zone 7 was seen in 2 patients in both hips.

Rivaroxaban is a novel, oral, once-daily, direct Factor Xa inhibitor in advanced clinical development. RECORD1 was a multinational, randomized, double-blind, double-dummy, phase III study investigating the efficacy and safety of extended thromboprophylaxis with rivaroxaban compared with subcutaneous enoxaparin following THR.

Patients (N=4541) were randomized to receive oral rivaroxaban 10 mg (6–8 hours after surgery and once daily thereafter) or subcutaneous enoxaparin 40 mg (administered the evening before surgery, 6–8 hours after surgery, and once daily thereafter) for 35±4 days. The primary efficacy outcome was the composite of deep vein thrombosis (DVT: symptomatic or detected by mandatory, bilateral venography if asymptomatic), non-fatal pulmonary embolism (PE), and all-cause mortality up to day 36±6. Major venous thromboembolism (VTE), the composite of any DVT, non-fatal PE and VTE-related death, was a secondary outcome. Safety endpoints included major and non-major bleeding while receiving study medication.

Rivaroxaban significantly reduced the incidence of the primary efficacy outcome compared with enoxaparin (1.1% vs 3.7%, respectively; p< 0.001; relative risk reduction [RRR] 70%). Rivaroxaban also significantly reduced the incidence of major VTE compared with enoxaparin (0.2% vs 2.0%, respectively; p< 0.001; RRR 88%). There were no significant differences in the incidence of major bleeding (0.3% vs 0.1%; p=0.178) or non-major bleeding (5.8% vs 5.8%; p=1.000) between rivaroxaban and enoxaparin, respectively. There was no evidence of liver safety issues associated with rivaroxaban.

Thromboprophylaxis with once-daily, oral rivaroxaban was significantly more effective than subcutaneous enoxaparin following THR without an increased risk of bleeding. This trial demonstrates the efficacy and safety of a fixed, unmonitored, once-daily dose of oral rivaroxaban for extended thromboprophylaxis after THR.

Data from recent AOANJRR shows a higher incidence of acetabular revision for dislocation of THA in uncemented compared to cemented THA (RR 1.59). We hypothesized that a difference in accuracy of component placement may be a factor. We aimed to assess any difference in accuracy between these 2 types of THA.

Patients undergoing navigated THA were prospectively recruited. Choice of uncemented or cemented THA was based on individual surgeon’s routine practice and preference and no adjustments were made for this study. All THAs (Cemented Exeter-21 and uncemented Trident/Secur fit-20) were performed through a posterior approach.

Statistical analysis: the mean and 95% confidence intervals (or median and interquartile range (IQR) for non parametric data) for each measure in both groups. ANOVA and nonparametric Mann-Whitney U test (significance level 5%). Levene’s test for homogeneity, Comparison of frequencies with chi-squared test or Fishers Exact test. Bonferroni correction where necessary.

We demonstrated a significant difference in reproducibility between components. Four of 20 (20%) uncemented cups deviated from the target inclination by 5 degrees or more compared to none of 21 in the cemented group (p=0.048). Seven of the 20 (35%) of the uncemented cups deviated from the target version by 5 degrees or more compared to none of 21 in the cemented group (p=0.003). There was a significant difference between the groups with regard to deviation from planned leg length (p< 0.001). Deviation from target leg length of greater than 5mm was found in 36.4% of the uncemented cases as compared to 8.3% of the cemented cases although due to the small numbers this was not statistically significant (p=0.16).

Statistically significant reduced accuracy of cup placement is demonstrated with uncemented compared to cemented implants. It is harder to control implant positioning in uncemented implants than cemented implants.

The ability to drive represents autonomy and independence of individuals. For many patients not being able to drive severely restricts their social, personal and professional activities leading to adverse effects on their well being. This study assessed the current evidence on driving advice after total hip replacement (THR) and compared it with the real time ability of patients to drive their own cars after primary THR. We present a prospective review of car driving ability of 130 patients (80 males and 50 females) who were treated with THR.

The results show that 105 patients (81%) were able to drive within 6–8 weeks after surgery. It took more than 12 weeks for 22 patients (17%) to start driving again. There was no reported deterioration in the driving ability after primary total hip replacement surgery. Conversely, 49 patients (38%) felt a subjective improvement in their driving capability after THR. Three patients (2%) were still not confident to drive even at 12 weeks post THR. In spite of the clear advice, only 69% practiced on a stationary car before driving on the road. In our study sample 67 patients (63.8%) had a right THR and 65 patients (61.9%) were manual car drivers and all were able to drive between 6–8 weeks.

This study demonstrates that patients should not resume driving motor vehicles for a minimum period of six weeks following total hip replacement surgery. This is inclusive of automatic and manually operated automobiles, and irrespective of laterality of surgical interventions. Return to driving after a six week period should be based on the individual’s capability and confidence to control the vehicle safely. Patients should be given clear advice to practice on the stationary vehicles before starting to drive on the road.

Printed plain radiographs have traditionally been the method of image transfer between hospitals, but the advent of digital imaging has revolutionised modern day radiology. It is now commonplace for compact discs to be used as the transport media for digital images, the theoretical advantages being ease of transport and storage, integration with PACS systems and the ability to perform image manipulation. However, in our tertiary referral centre for pelvic and acetabular trauma, we noted problems with digital image transfer using this method.

We examined the last 25 compact discs sent to our unit for functionality on 3 separate computers. Only 17/25 discs loaded on all computers, and 2 discs failed to load on any computer. 9 of the remaining 23 discs did not allow image manipulation, and 1 disc would not allow retrieval of all the contained images. 5 of the 23 discs took longer than 5 minutes to retrieve the contained images. In summary, we classed 10 of the 25 discs as acceptable. Patient transfer to our unit was not delayed, but 4 patients underwent repeat CT scans due to incomplete imaging

Digital technology has made great advances into medical imaging. Standardisation using the DICOM format for image creation has attempted to eliminate issues of compatibility, but variation in software used to produce and view images can still vary from these standards. Technical errors in the creation of discs should be eliminated at source, and it is mandatory that referring units check the functionality of discs before they are sent. In this way, the potential for delay to transfer and subsequent repeat exposure to ionising radiation can be avoided.

Objectives: to determine whether initial contact with emergency services via a mobile phone (MP) in life threatening situations is associated with increased survival or reduced length of stay when compared to contact via a landline.

A retrospective cohort – data from all emergency dispatches from a UK county ambulance service was linked to the Patient Admission System at local hospitals. All emergency dispatches for immediately life-threatening events (designated as Code Red) between 01/01/1995 and 31/06/2006 were tracked to death or discharge.

Main Outcome Measures:

Mortality (at scene, at emergency department, and during hospitalisation), admissions (to the emergency department (ED), inpatients care, and the intensive care unit (ICU)) and mean lengths of stay were analysed by initial exposure (MP versus landline) using multi-variant analysis with logistic regression controlling for potential confounding variables.

354,199 ambulances were dispatched in the 11.5 years. Mobile phone use rose to 25% by study end. 66% of ambulances subsequently transferred patients to hospital. MP compared to landline reporting of emergencies resulted in significant reductions in the risk of death at scene for medical events (OR 0.74; 95% CI 0.65 to 0.85), but not for trauma (OR 1.04). ED medical deaths were higher (OR 1.33; 95% CI 1.33 to 1.72) as were in-patient (OR 1.19). There was no effect on ED or hospital trauma deaths (ORs 0.81, 0.84). The probability of being admitted to hospital and ICU was higher with MP call for trauma (ORs 1.22, 1.44). There was no difference in mortality between mobile or landline calls from either urban or rural areas.

There is little evidence to suggest a lower threshold to make an emergency call from a MP. The potential advantages of MP use of ease of access, supplying bystander/patient advice and shortening the ‘golden hour’ appear confined to non-trauma emergencies.

Since 2003 Trauma and Orthopaedic trainees in the UK and Ireland have routinely submitted data recording their operative experience electronically via the eLog-book. This provides evidence of operative experience of individuals and national comparisons of trainee, trainer, hospital and training programme performance. We have analysed trauma surgery data and established standards for training.

By January 2008 there were over 4 million operations logged. Operations performed and uploaded since 2003 have been included. Each trainee’s work is analysed by ‘year-in-training’. Data on levels of supervision, missed opportunities (where the trainee assisted rather than performed the operation) was analysed. The average number of trauma operations performed annually by trainees was 109, 120, 110, 122, 98 and 84 (total 643) for YIT one (=ST3) to six (=ST8) respectively. There were only 22% of missed opportunities throughout six years of training. A high level of experience is gained in hip fracture surgery (121 operations) and forearm (30), wrist (74) and ankle (47) operative stabilisation over the six years. However, the average number of tibial intra-medullary nails (13), external fixator applications (12) and childrens’ elbow supracondylar fracture procedures (4) performed is low. We are also able to identify trainees performing fewer operations than required during their training (two standard deviations or more below the mean for their YIT). We expect a trainee to have performed at least 255, 383, 473, and 531 trauma operations at the end of YIT three to six respectively.

The eLogbook is a powerful tool which can provide accurate information to support in-depth analysis of trainees, trainers, and training programmes. This analysis has established a baseline which can be used to identify trainees who are falling below the required operative experience.

Roentgen Stereophotogrammetric Analysis (RSA) can predict long-term outcome of prostheses by measuring migration over time. The Exeter femoral stem is a double-tapered highly polished implant and has been shown to subside within the cement mantle in 2 year RSA studies. It has a proven track record in terms of long-term survivorship and low revision rates. Several studies have demonstrated excellent clinical outcomes following its implantation but this is the first study to assess stem migration at 10 years, using RSA.

This is a single-centre study involving 20 patients (mean age: 63 years, SD=7) undergoing primary total hip replacement for degenerative osteoarthritis using the lateral (Hardinge) approach. RSA radiographs were taken with the patient bearing full weight post-operatively, at 3, 6, 12 months and at 2, 5 and 10 years follow-up. The three-dimensional migration of the Exeter femoral stem was determined.

The mean Oxford Hip Score at 10 years was 43.4 (SD=4.6) and there were no revisions. The stems subsided and rotated internally during a 10-year period. The mean migrations of the head and tip of the femoral stem in all three anatomic directions (antero-posterior, medio-lateral & supero-distal) were 0.69 mm posterior, 0.04 mm lateral and 1.67 mm distal for the head and 0.20 mm anterior, 0.02 mm lateral and 1.23 mm distal for the tip. The total migration at 10 years was 1.81 mm for the head and 1.25 mm for the tip.

The Exeter femoral stem exhibits migration which is a complex combination of translation and rotation in three dimensions. Comparing our 10 year with our previous 2 year migration results, the Exeter stems show continued, but slow distal migration and internal rotation. The subsidence continues to compress the cement and bone-cement interface which maintains secure fixation in the long term.

Ruptures of the patellar and/or quadriceps tendon are rare injuries requiring immediate repair to re-establish knee extensor continuity and to allow early motion. Ultrasound is extensively used as a diagnostic tool before surgery on acute traumatic tears of the patellar tendon and quadriceps tendons.

Our aim was to re-evaluate the value/role of sonography in diagnosing quadriceps and patellar tendon rupture and in differentiating partial from complete tears. To correlate the intra operative findings with the ultrasound report.

A retrospective review of 32 consecutive patients who had a surgical intervention for suspected acute quadriceps and patellar tendon rupture over the last 3 years. Intra-operative findings, clinical, x-ray, ultrasound and MRI reports were correlated.

Seventeen patients had a suspected patellar tendon rupture on clinical examination and 15 patients had suspected quadriceps tendon rupture. Diagnosis was confirmed by clinical examination and x-rays alone in 9 patients, with additional ultrasound in 18 patients and with MRI scan in 5 patients. There were 6 false positives out of 18 [33.3%] in the ultrasound proven group and 1 false positive out of 9 [11.1%] in the clinical examination and x-ray only group. MRI was 100% accurate [n=5].

This is a small, but important study. Ultrasound offers a low degree of sensitivity and specificity in diagnosing acute quadriceps and patellar tendon ruptures. As a result, patients are being exposed to the risks of surgery unnecessarily. We recommend MRI scan as a first line of investigation in patients where the diagnosis is clinically ambiguous. Ultrasound assessment should not be relied upon in when making the decision to operate.

The incidence of degenerative scoliosis in the lumbar spine is not known. In the ageing population deformity may coexist or cause stenosis. MRI gives limited information on this important parameter in the treatment of stenosis. The aim of this study was to highlight the incidence of coronal abnormalities of the lumbar spine dependent on age in a large population of patients.

We reviewed all abdominal radiographs performed in our hospital over ten months. 2276 radiographs were analysed for degenerative lumbar scoliosis and lateral vertebral slips in patients who are over 20 years. Evidence of osteoarthritis of the spine was also documented. Radiographs were included if the inferior border of T12 to the superior border of S1 was visualised and no previous spinal surgery was evident (metal work).

2233 (98%) radiographs were included. 48% of patients were female. The incidence of degenerative lumbar scoliosis, lateral listhesis and osteoarthritis increased with age. Degenerative scoliosis was present in 1.6% of 30–39 year olds increasing every decade to 29.7% of patients 90 years or older. In all age groups curves were more frequent and had greater average Cobb angles in female patients.

Degenerative lumbar scoliosis starts to appear in the third decade of life increasing in frequency every decade thereafter, affecting almost a third of patients in the ninth decade. It is more common in female patients and has a greater magnitude. Deformity may be even greater on standing views and is important to recognise in all patients that are undergoing lumbar spinal decompressive surgery. A failure to do so may lead to inferior results or the need for further surgery.

The aim of the study was to assess the safety of a novel anatomical landmark in the placement of thoracic pedicle screws. It is our clinical observation that the sagittal plane of the screw trajectory is perpendicular to the plane of the superior articular facet, when the entry point is in the lateral half of the articular surface of the corresponding superior facet.

Using SECTRA software on a PACS digital imaging system, morphometric analysis was performed on thoracic vertebrae imaged using computed tomography (CT). For inclusion, the scan had to have no reported bony abnormality. It was determined whether a trajectory as described at 90 degrees to the articular facet, with an entry point just caudal to the lateral half of the facet to a depth of 25mm would breach either the medial wall of the pedicle or lateral vertebral body wall anterior to the costovertebral facet.

Sixty-two CT scans (744 segments, 1488 pedicle-facet complexes) were reviewed. 1154 complexes were suitable for full analysis. Exclusions were due to the lumbarisation of the T12 facet joints (62) or inability to clearly define the facet surface due to the plane of the CT slice (272). Of 1154 entry points assessed, 1154 (100%) were safe to be entered at 90 degrees to a depth of at least 25mm.

We have demonstrated the safety and reliability of a novel anatomical landmark in normal thoracic pedicles. We believe this will improve sagittal plane alignment and reduce further the risk of medial pedicle breach.

Acute osteoporotic vertebral compression fractures (VCFs) are frequently misdiagnosed as there is often no history of preceding trauma. VCFs not only cause back pain, but can also result in a loss of function, spinal deformity and increased mortality. Cement augmentation has been shown to effectively treat these fractures. It is impossible to diagnose an acute fracture on plain x-ray and therefore identify those likely to benefit from this treatment. The definitive investigation to determine the presence of an acute fracture is a MR scan, but this is a limited resource. The aim of this paper is to evaluate 2 new clinical signs which we believe aid in the diagnosis of an acute VCF: firstly closed fist percussion at the level of an acute VCF resulting in a severe, sharp fracture pain, and secondly the inability of a patient to lie supine. This was a prospective study of 78 patients with suspected acute VCFs.

48/78 had an acute fracture on MR. 42/45 patients who were positive for closed fist percussion, had an acute fracture on their MR scan. There were 6 patients who were negative for closed fist percussion who had an acute fracture (sensitivity 87.5%, specificity 90%).

39/41 patients who were positive for the supine sign had an acute fracture on their MR scan. There were 9 patients who were comfortably able to lay supine who had an acute fracture (sensitivity 81.25%, specificity 93.33%).

Either a positive closed fist percussion sign or a positive supine sign is a reliable indicator of the presence of an acute VCF. By incorporating these signs into our routine clinical assessment we are better able to predict which patients have an acute fracture, and therefore decide which patients need a MR scan.

Very few reports exist regarding use of intra-operative autologenous transfusion in adult spinal fusion surgery. Specific indications for use of cell saver in thoraco-lumbar spinal instrumentation are not clearly determined. Our objective was to identify the clinical factors associated with increased risk of intra-operative blood loss. To analyse the safety and benefits of using cell saver and to determine the cost-effectiveness.

51 consecutive thoraco-lumbar instrumented fusion over 14 months reviewed. There was no randomisation. Cell saver group consisted of 25 patients and control group consisted of 26 cases. Patients with degenerative scoliosis and tumours excluded. Clinical notes were reviewed.

Demographic data were comparable between the two groups. Iliac crest bone graft harvested in 20% of cell saver group and 40% in control group. Levels of fusion ranged from 1–7 (Mean=2.8) in the cell saver group and 1–4 (Mean=1.9) in the control group. Mean duration of surgery was 15 minutes longer in study group. Intra-operative blood loss was higher in cell saver group (mean=1245 mls vs 800 mls). Significant indicators for duration of surgery were number of levels fused (p< 0.0001), patient weight (p=0.003) and revision surgery (p=0.029). Significant indicators for predicting blood loss were number of levels fused (p< 0.001) and duration of surgery (p=0.0304). 20% in study group (8 units of red cells) and 26% in control group (17 units of red cells) required blood transfusion. Percentage drop in the post-operative haematocrit was 19.1 in study group compared to 36.3 in control group.

In conclusion, 44.38% blood salvaged (35–38% in spinal literature). Use of cell saver significantly decreased post-operative need for blood transfusion. Number of levels of fusion, duration greater than 4 hrs and a low pre-op Haemoglobin/Haematocrit were significant parameters in predicting intra-operative blood loss. If blood loss is less than 700 mls, gains from cell saver are debatable.

We analysed the outcome of the Coonrad-Morrey total elbow replacement used for fracture of the distal humerus in elderly patients with no evidence of inflammatory arthritis and compared the results for early versus delayed treatment.

We studied a total of 32 patients with 15 in the early treatment group and 17 in the delayed treatment group. The mean follow-up was 56.1 months (18 to 88). The percentage of excellent to good results based on the Mayo elbow performance score was not significantly different, 84% in the early group and 79% in the delayed group. Subjective satisfaction was 92% in both the groups. One patient in the early group developed chronic regional pain syndrome and another type 4 aseptic loosening. Two elbows in the early group also showed type 1 radiological loosening. Two patients in the delayed group had an infection, two an ulnar nerve palsy, one developed heterotopic ossification and one type 4 aseptic loosening. Two elbows in this group also showed type 1 radiological loosening. The complication rates in the early and delayed treatment group were 13% and 29% respectively. The Kaplan-Meier survivorship analysis for the early and delayed treatment groups was 93% at 88 months and 76% at 84 months, respectively. No statistically significant difference was found between the two groups.

We conclude that total elbow replacement provides a preditable and reproducible outcome in terms of pain relief and functional range of movement in elderly osteoporotic patients with difficult distal humerus fractures.

We aimed to evaluate the effects of implementing blood conservation strategies on transfusion requirements in adult patients undergoing scoliosis correction surgery. We retrospectively studied 50 consecutive adult patients who underwent scoliosis correction surgery (anterior, posterior or combined) between 2003 and 2007. All patients had a standard transfusion protocol. Age, BMI, pre and post operative haemoglobin, levels fused, duration of surgery, hospital stay, anti-fibrinolytics used and blood transfused was noted.

50 patients with mean age 24.6 years and mean BMI 21.9 kg/m2 were studied. 14 patients had anterior surgery, 19 patients had posterior surgery and 17 had combined anterior and posterior procedures. Mean number of levels fused was 9.5 (6–15) and mean duration of surgery was 284.6 minutes (135–550 minutes). Antifibrinolytics were used in 31 patients (62%), Aprotinin in 21(42%) and Tranexamic acid in 10 (20%). Mean blood loss in patients who received anti fibrinolytics was 530mls while mean blood loss in the other patients was 672mls. (p< 0.05). Blood transfusion was not required in any of the patients undergoing anterior correction only while 7 patients (41%) undergoing anterior and posterior correction and 3 patients (15.8%) undergoing posterior correction only required blood transfusion. Mean volume of cell saved blood re-transfused was 693.8 mls and mean hospital stay was 9.2 days. Mean pre-op haemoglobin was 13.2 g/dl (10.4–17.4) and mean post-op haemoglobin was 10.7 g/dl (7.7–15). 4 patients (8%) required intra and post-operative blood transfusion while 6 patients (12%) required blood transfusion postoperatively.

In conclusion, the use of anti-fibrinolytics like Aprotinin and Tranexamic acid reduces blood loss in scoliosis surgery. In the current scenario, with Aprotinin no longer available for use, our study would recommend the use of Tranexamic acid alongwith other blood conservation measures. In our unit we do not have blood cross matched for anterior surgery alone.

Pyogenic haematogenous spinal infection in the elderly, described as spondylodiscitis, vertebral osteomyelitis and epidural abscess is considered a rare but life threatening condition. Our objective was to test the hypothesis that low index of suspicion leads to delayed diagnosis and referral for definitive treatment resulting in increased and perhaps avoidable medical morbidity, social drift including early mortality and to analyse pathological entities, complications and optimum treatment options.

We performed a retrospective review of medical records over 10-year period. Post-operative infections and patients under 65 years old excluded. Initial presentation, investigations and differential diagnosis, time to diagnosis, date and day of referral, mode of definitive treatment, pathologic entities, complications and outcomes were noted. Patient outcomes were measured as duration of treatment, length of hospital stay, complications, ambulatory status, complications, discharge destination and death. Outcomes were correlated with delayed diagnosis and referral.

46 elderly (age> 65) patients with a mean age of 71 years (range=65–91). 62% referral from physicians. Fever with malaise associated with chronic LBP was the commonest presenting complaint. There were 31 patients with discitis, 12 epidural abscess and 3 osteomyelitis. Lumbar spine was affected in 63% patients. Time to diagnosis ranged from 2–17 days with mean of 8 days. Mean referral time was 9 days with 39% referrals on Friday. Staphylococcus aureus (47%) was the commonest organism isolated. Duration of hospitalisation ranged from two to twelve weeks. 46% required surgical decompression with four cases of related mortality during acute hospital stay.

Time duration to spinal referral had direct correlation with increase in morbidity, social drift and mortality. The incidence of haematogenous spinal infection in the elderly has increased over the years in our series, contrary to popular belief. A high index of suspicion in elderly patients with PUO promotes early diagnosis and optimises outcome.

In severe destructive spinal infections, with neurological deficit, progressive deformity or uncontrolled sepsis, the mainstay of treatment is surgical debridement with anterior and posterior stabilisation. We retrospectively reviewed 14 patients (11 Male 3 female) with a mean age of 63 (range 38 to 85) who underwent anterior only surgery consisting of an expandable vertebral body cage and a ventrolateral locking plate (Synthes). Organisms included Tuberculosis (7), Staphylococcus (5), E-Coli (1) and Pseudomonas (1). Radiological and functional outcomes were assessed upto 18 months post surgery. Cobb angles were used to measure angular deformity.

Good early results in terms of safety, resolution of pain, control of deformity and improvement of neurological deficits was observed. Average blood loss was 633mls (range 300mls to 1500mls) with a mean deformity correction of 23 degrees. Post operative radiological assessment showed the cages to be relatively stable in the under 80 yrs groups (mean loss of correction 15 %). In elderly patients (> 80 yrs) there was significant subsidence leading to a loss of correction (mean 52%) which required stabilisation using vertebral body cement augmentation. In one case, there was implant displacement requiring revision and additional posterior stabilisation. 11 patients showed significant improvement in neurology and 3 patients remained neurologically normal ie Frankel E.

We propose assessing severe spinal infections using the spinal trilogy of neurological deficit, deformity and sepsis. Anterior stabilisation using an expandable cage and locking plate alone or with additional vertebral body cement augmentation in elderly patients provides a satisfactory solution for severe destructive spinal infections. It preserves the posterior column and reduces the need for further posterior surgery.

Sacroiliac joint (SIJ) is a diarthrodial joint and can often be a source of chronic low back pain complex. We present a percutaneous technique for SIJ fusion and the functional and radiological outcome following arthrodesis with HMA (Hollow modular anchorage; Aesculap Ltd, Tuttlingen) screws.

Fifteen consecutive patients operated for SIJ fusion between Sep 2004 and Aug 2007 were included in the study. The diagnosis was confirmed with MRI and diagnostic injections. Pre-operative and post-operative functional evaluation was performed using SF-36 questionnaire and Majeed’s scoring system. Postoperative radiological evaluation was performed using plain radiographs. The HMA screws packed with bone substitute were implanted percutaneous under fluoroscopic guidance.

The study group included 11 females and 4 males with a mean age of 48.7 years. Mean follow-up was 14 months. Mean SF-36 scores improved from 37 to 80 for physical function and from 53 to 86 for general health. The differences were statistically significant (Wilcoxon signed rank test; p < 0.05). Majeed’s score improved from mean 37 preoperative to mean 79 postoperative. The difference was statistically significant (student t test, p< 0.05). 13 had good to excellent results. The remaining 2 patients had improvement in SF-36 from mean 29 to 48. Persisting pain was potentially due to coexisting lumbar pathology. Intra-operative blood was minimal and there were no post-operative or radiological complications.

Percutaneous HMA screws are a satisfactory way to achieve sacroiliac stabilisation.

Osteoporotic vertebral fractures predispose to significant morbidity in the elderly and are strongly associated with an overall decline in health, functional status and social drift.

In recent years various surgical morphoplastic techniques have been employed in an attempt to improve on the disappointing natural history of this manifestation of biological failure.

Current evidence supporting the use of kyphoplasty versus medical management alone in the management of these factures is limited and based on several small prospective cohort studies.

We present prospectively collected data supporting the use of kyphoplasty in a U.K. based population tested by examining Visual Analogue Pain Score (VAS), vertebral height, vertebral and kyphosis angles, Oswestry Disability Index and Hospital Anxiety and Depression Score (HADS).

50 patients in our kyphoplasty group have undergone 91 kyphoplasty procedures. With a mean follow up of 6 months, the mean post-operative VAS score was 3.8 versus a pre op score of 8.5. This reduction was maintained at 6 weeks and 6 months with mean scores of 3.3 and 2.7 respectively (p< 0.001).

Functional status ODI scoring improved from a pre-operative score of 54 to 47 post-operatively, to 40 at 6 weeks, and further, to 39 at 6 months. This result was reinforced by HADS scoring at the same time intervals recording 15.0, 11.2, 11.1 and 11.7 respectively.

Post-operative radiographs demonstrated a 24% mean increase in the vertebral angle (p< 0.01) with increases in the anterior, middle and posterior vertebral body heights of 19, 31 and 9% respectively (p< 0.001). No significant improvement of kyphosis angle was identified.

The Derby experience demonstrates that kyphoplasty can improve pain and functional status and may help correct deformity after osteoporotic vertebral compression fractures.

Our experience has encouraged further recruitment for kyphoplasty as the preferred management for those patients who fail to respond to initial non-operative management.

Failed Back Surgery Syndrome (FBSS) refers to having persistent back and/or leg pain after one or more surgical procedures aimed at correcting lumbosacral disease. Different modalities including Epidural injections, Spinal cord stimulation, Anterior/Posterior Lumbar Interbody Fusion (ALIF, PLIF) have been described in the literature with varying outcome. Our aim was to review the functional outcome of patients treated with Posterior Lumbar Interbody Fusion for FBSS since June 2000 to December 2006.

This is a retrospective study of prospectively collected data of 25 patients diagnosed with FBSS and treated with PLIF at University Hospital of North Tees. All patients were requested to fill in the Oswestry Disability Index(ODI), Numerical Rating Scale for Back Pain (NRSBP), Numerical Rating Scale for Leg Pain (NRSLP), SF36 pre and post operatively. The scores were analysed using SPSS software for statistical significance.

There were 12 men and 13 women. Mean age was 47.8 years (range 31–76 years). Mean follow up was 24.8 months (range 4 – 63 months). Four of the 25 patients had Post discectomy syndrome while the rest had post laminectomy syndrome. Most common level of surgery was L5/S1 either as a single level or in combination with other levels above. ODI decreased from a pre-op mean of 55.6(range 20–74.1) to 20.6(range 2–54) while VASBP decreased from 6.9 (range 1–9) to 2.2(range 0–6) (p< 0.05) and VASLP decreased from 6.4 (range 3–10) to 2.2 (range 0–7) (p< 0.05). SF36BP scores improved from a mean 26.7 (range 12–37.1) before the surgery to 45 (range 31–62) (p< 0.05) after surgery. 84% of the patients felt that the outcome of the surgery met their expectation and were satisfied with result.

Our results show that PLIF can be offered as a safe and effective for treatment of FBSS.

We performed a retrospective follow-up study investigating the safety and efficacy of an independently constructed non-linked double rod system for anterior column reconstruction.

Our objective was to demonstrate safe and cost effective adaptation of a standard deformity system for use in anterior column reconstruction.

Anterior only surgery in patients requiring corporectomy spares the posterior soft tissue envelope. Corporectomy and neural decompression is followed by insertion of a titanium mesh cage and bone graft. Several non-adaptable implant systems (locking plates and linked-rod constructs) have been validated both in clinical and in-vitro studies and are available to the surgeon. These devices can only be used to address the anterior column and can only span a limited number of spinal segments.

Twenty-two patients have undergone anterior column reconstruction for tumour (8), trauma (11) and infection (3) in our unit are included. Mean follow up was 30.5 months. All had anterior corporectomy and decompression, insertion of a titanium mesh cage and stabilisation with an anterior non-linked dual rod construct (Synthes USS II). Follow-up records and radiographs have been analysed.

Ninety-five percent of patients fused clinically and radiologically on plain radiograph examination. There was no failure of metalwork or deterioration in neurological function following surgery. There were 5 deaths in the study group, 4 from progression of metastatic malignant tumour and one within 30 days of surgery. Three patients have had local malignant disease recurrence, two requiring posterior decompression and one requiring further anterior surgery.

This system is effective and safe. It allows fewer implants to be carried by individual hospitals and thus reduces hospital costs.

Randomised controlled clinical trials (RCTs) produce the most reliable evidence about the effects of clinical care. In surgical trials, lack of surgeons’ individual equipoise (state of genuine uncertainty about treatment arms) appears to be one of the greatest obstacles. Collective equipoise based on present or imminent controversy in the expert medical community has been proposed as a solution (Freedman, 1987), but could be applied only at the beginning of a trial to a general trial question.

We developed a system that quantifies collective uncertainty among a group of surgeons for an individual clinical case. After a successful pilot study the system was introduced as an independent project within the UK Heel Fracture Trial. The expert panel included 10 surgeons from 8 hospitals. Anonymous clinical data of potentially eligible consecutive cases including CT and X-ray images was published on a secure online forum after 6 weeks follow up clinic to avoid interference with clinical course. Surgeons registered in the panel estimated the probability that the patient would be better or worse by various degrees with operative treatment.

30 clinical cases have been analysed, including 6 bilateral fractures (otherwise excluded). 86.7% could be recommended for inclusion in the trial, compared to 43.3% recruited out of this series in the actual trial. Lack of individual uncertainty within the panel was present in every case.

The system not only has a potential to improve recruitment in surgical RCTs, but provides ethically sound grounds to offer or otherwise a patient participation in a trial. Surgeon’s individual equipoise dilemma and responsibility is shared with colleagues. Cases that otherwise will be excluded can be evaluated with broader inclusion criteria. The system is easy to use, cheap and reliable. Limitations include surgeons’ compliance and time lapse (at least 48 hours) for voting to be completed.

A study to evaluate the efficacy of combined grafting (iliac crest autograft – ICAG, and human recombinant osteogenic protein 1 – rhOP1/BMP7) for long bone fracture non-unions (LBFNUs).

At both institutions prospective and retrospective data were collected. (Between Oct 2001 and Aug 2004 all LBFNUs that were grafted with a combination of BMP7 and ICAG). The records of the initial injury incident, treatment course, all operative interventions before and after the combined grafting and the follow up till final clinical & radiological union have been analysed. X2 test was used to analyse the results.

Forty-nine patients (31 males) with a mean age of 43 years (18–79) with LBFNUs were identified. The mean follow-up was 21.4 months (12–65). 7 were humeral, 13 femoral, and 29 tibial LBFNUs. Eleven were open (3 grade II, 8 grade IIIa–b). All non-unions were atrophic, and 8 had significant bone defects. The mean number of operations prior to the combined grafting was 2.5 (0–6). Clinical and Radiological union occurred within a mean time of 4.4 (3–12) months and 5.4 (4–16) months respectively. All of the fractures united. One patient, with an infected tibial non-union after an open fracture, ultimately underwent a below knee amputation. No complications or adverse effects from the use of BMP-7 were encountered.

BMP-7 was used as a bone-stimulating agent combined with conventional iliac crest bone grafting with a success rate of 98% in this series of patients with LBFNUs. This study supports the view that this combination of BMP-7 is safe and a power adjunct to be considered in the surgeon’s armamentarium for the management of such difficult cases.

Current evidence on the indications for and efficacy of non-rigid lumbar stabilisation remains unclear. The aim of this study was to review the outcome of the DYNESYS system (Zimmer, Inc.) in a consecutive series of 34 patients undergoing this procedure between 2001 and 2006.

Prospectively collected outcome measure data obtained pre-operatively and at 1 year post-operatively was analysed using the Wilcoxon Signed Rank Test. Kaplan Meier survival analysis was performed using revision surgery as the end point. Cox Regression was utilised to identify variables that were related to implant survival.

Pain rating on the visual analogue scale improved from a mean of 7 pre-op to 4 at 1 year (p=0.009), Roland Morris Disability Questionnaire scores from 13 to 9 (p=0.02), Modified Somatic Perception Questionnaire from 13 to 9 (p=0.03). When reporting subjective outcome, 54% of patients reported “better” or “much better” outcomes at last followup (12–69 months post op). Eight patients (25%) required removal of the implant and conversion to fusion, one of whom had deep infection. Kaplan Meier survival analysis revealed a survival of 78% at 5 years (95% CI, 60 – 96%). Previous spinal surgery was significantly related to the time of survival of the implant (p=0.008).

Our study has demonstrated a high revision rate for this implant and 54% patient satisfaction. We recommend that patients be counseled regarding these risks and further use of this implant should be subject to the outcome of larger studies and randomised controlled trials.

Sub-optimal positioning of the implant is thought to be related to poor outcome after Lumbar Disc Replacement. Our aim was to analyse the impact of implant position in the outcome of Charite III Disc Replacement implants.

160 Charite III Lumbar Disc Replacements that were implanted between 1990 and 2000. The average age was 46 years with 62 Males and 98 Female subjects. An independent observer (HN) administered Pain score (VAS 1–10) for Low Back Pain (LBP) and Oswestry Disability Index (ODI). These clinical outcome parameters were compared with coronal and sagittal position of the implants from the latest available radiographs. Those with operation at L3L4 (small numbers = 20) and inadequate radiographs were excluded.

48 implants were optimally placed and 70 implants were placed sub optimally. Both the groups were in similar age groups (45.02 years, SD 7.61 and 48.31 years, SD 8.04). Clinical: No statistical or clinically significant difference was observed in LBP on VAS (4.92 V/S 4.41), ODI (42.8 V/S 38.0) and in Patient Satisfaction at an average follow up of 70 months. Average movement at optimally placed discs at L4L5 was 4.4o(95% CI 2.3 – 6.7) and at L5S1 was 5.9o(95% CI 4.2 – 7.5) and at sub optimally placed disc at L4L5 was 3.8o(95% CI 2.4 – 5.1) and at L5S1 was 3.8o(95% CI 2.3 – 5.3).

Clinical and radiological results after Charite III Disc Replacement is NOT dependent on positioning of implants. Movements at optimally placed implants are better but is of questionable clinical relevance.

This is the first six-year report of a prospective longitudinal study of daily output of cobalt and chromium in urine and their levels in blood following hybrid metal-on-metal surface arthroplasty.

Urine and whole blood specimens were analyzed before and periodically after hip resurfacing in 26 male patients after informed consent (mean age 52.9 years, mean BMI 27.9). Two of these patients have undergone contralateral hip resurfacings for progressive pain from end-stage arthritis and had to be excluded.

All patients were found to have well-functioning resurfacings at 6-year follow-up. No patient complained of persistent pain or disability. The median 6-year Oxford hip score was 12. Urine chromium and cobalt at six years were 3.9 and 7.8 μg/24 hrs and blood levels were 1.11 and 1.17μg/l respectively. Both urine and blood levels show a statistically significant early increase reaching a peak six months to one year postoperatively followed by a steady decrease over the following five years, although the individual reductions are not statistically significant, except for blood chromium where the 4 and 6 year levels were significantly lower than the 1-year level.

Elevated systemic metal exposure following MM bearing arthroplasty continues to cause concern. Our results show that metal release in these bearings shows a reducing trend after an initial peak dispelling the fear that a steady build-up of in vivo metal occurs with progressively increasing blood levels. However, as long as the significance of these elevated levels remains unknown, the need for continued vigilance persists.

Patients with a femoral shaft fracture requiring intra-medullary nailing were recruited to investigate if the femoral canal could be a potential source of inflammatory cytokines, previously implicated in the pathogenesis of life-threatening inflammatory complications.

Femoral and peripheral blood samples were obtained at the time of surgery from patients with a femoral shaft fracture requiring intramedullary nailing. The local femoral intramedullary and peripheral release of a group of ten Th1 and Th2 cytokines concentrations (IL-1b, IL-2, IL-4, IL-5, IL-6, IL-8, IL-10, GM-CSF, TNF-a and IFN-g) after femoral shaft fracture and intramedullary reaming, if performed, was measured using a Human Cytokine Antibody 10-plex Bead Kit. A control group of patients(n=3) undergoing hip replacement was established to allow comparison with the normal femoral intramedullary cytokine environment.

21 patients with a femoral shaft fracture were recruited. Femoral shaft fracture caused a significant increase in the local femoral concentrations of IL-6 (median 3967pg/ml; range 128–25,689pg/ml) and IL-8 (median 238pg/ml; range 8–8,288pg/ml) compared to the femoral control group(p=0.0005 and p=0.001 respectively). No significant local femoral release of the other cytokines was demonstrated. In the patients who underwent intramedullary reaming of the femoral canal (n=6), a further significant local release of IL-6 (median post-ream 15,903pg/ml; range 1,854–44,922pg/ml) and IL-8 (median post-ream 1,443pg/ml; range 493–3,734pg/ml) was demonstrated (p=0.01 and p=0.03 respectively), thus showing that intramedullary reaming can cause a significant local inflammatory response.

Femoral shaft fracture produces a local inflammatory response releasing large amounts of the cytokines IL-6 and IL-8 into the local femoral environment but not of the other Th1 and Th2 cytokines studied. Reaming, produced significant elevation in local femoral IL-6 and IL-8 concentration, suggesting a local femoral response as a result of this procedure. Possibly, local femoral environment may act as a cell-priming or stimulating zone, for circulating inflammatory cells.

Our aim was to investigate the molecular features of progressive severities of cartilage damage, within the phenotype of Anteromedial Gonarthrosis (AMG).

Ten medial tibial plateau specimens were collected from patients undergoing unicompartmental knee replacements. The cartilage within the area of macroscopic damage was divided into equal thirds: T1(most damaged), to T3 (least damaged). The area of macroscopically undamaged cartilage was taken as a 4th sample, N. The specimens were prepared for histological (Safranin-O and H& E staining) and immunohistochemical analysis (Type I and II Collagen, proliferation and apoptosis). Immunoassays were undertaken for Collagens I and II and GAG content. Real time PCR compared gene expression between areas T and N.

There was a decrease in OARSI grade across the four areas, with progressively less fibrillation between areas T1, T2 and T3. Area N had an OARSI grade of 0 (normal). The GAG immunoassay showed decreased levels with increasing severity of cartilage damage (p< 0.0001). There was no significant difference in the Collagen II content or gene expression between areas. The Collagen I immunohistochemistry showed increased staining within chondrocyte pericellular areas in the undamaged region (N) and immunoassays showed that the Collagen I content of this macroscopically and histologically normal cartilage, was significantly higher than the damaged areas (p< 0.0001). Furthermore, real time PCR showed a significant increase in Collagen I expression in the macroscopically normal areas compared to the damaged areas (p=0.04).

In AMG there are distinct areas, demonstrating progressive cartilage loss. We conclude that in this phenotype the Collagen I increase, in areas of macroscopically and histologically normal cartilage, may represent very early changes of the cartilage matrix within the osteoarthritic disease process. This may be able to be used as an assay of early disease and as a therapeutic target for disease modification or treatment.

The Cartilage Autograft Implantation System (CAIS) is being developed as a potential alternative surgical treatment providing chondrocyte-based repair in a single procedure for articular cartilage lesion(s) of the knee. Two pilot clinical studies were conducted to assess safety and initial performance of the CAIS system.

CAIS involves preparation and delivery of mechanically morselized, autologous cartilage uniformly dispersed on a 3-dimensional, bio-absorbable scaffold, and fixated in the defect with bio-absorbable staples. The mechanical fragmentation of cartilage tissue both maintains viability of the chondrocytes and creates increased surface area, which facilitates the outgrowth of embedded chondrocytes onto the scaffold. A proprietary disposable, arthroscopic device for precisely harvesting viable, morselized cartilage tissue was used. Two pilot clinical studies conducted in the EU and US were designed to assess safety and initial performance of the CAIS. The studies treated 53 patients at 10 enrolling sites, with microfracture as a control. Subjects returned for follow-up visits up to 3 years. Subjects were clinically evaluated and interviewed for the occurrence of adverse events and asked to complete clinical outcome questionnaires, Knee Injury and Osteoarthritis Outcome Score (KOOS), regarding disability, function, pain and quality of life. In addition, MRIs were completed at baseline, 3 weeks, and 6, 12, 24, and 36 months.

The instrumentation enabled the successful preparation and fixation of morselized autologous cartilage tissue loaded implant in a single intraoperative setting. The CAIS device has demonstrated short-term safety in subjects treated to date. Preliminary data from the US pilot study at 12 months and EU pilot study at 6 months indicate that CAIS is safe and its performance based on KOOS clinical outcomes show improvement over baseline and comparability to microfracture. Additional data must be analyzed regarding long-term safety and performance.

Impaired vascularity of the skin in elderly ankle fracture patients causes the skin and wound complications. This is part of a RCT comparing ORIF and close contact casting (CCC) for isolated unstable ankle fractures in patients > 60 years. Assessments over 6-months

trans-cutaneous O2 saturation (TcP02) of medial and lateral ankle skin

The uninjured limb was the control.

Eighty-nine patients eligible; 59 participated (76% female). 30 randomised to ORIF; 29 to CCC. Each had one death and one withdrawal. Vascular data available on 55. Two patients had delays in wound healing (> 25% for > 6-weeks). Two further developed wound infections. No skin breakdowns in CCC group. There was a reduced TcP02 on day-3 in the injured limb. The TcP02 rose at 6-weeks compared to day-3 (medial 58mmHg; lateral 53mmHg, p=0.002) in the injured leg. At 6-months the TcP02 measurements were not different to uninjured leg. A critical TcP02 (< 20mmHg) found in 4, correlated with skin problems (p=0.003). Two of these had the only major delays in wound healing and one of the two wound infections.

94% of participants had normal ABPI’s (> 1.0). There was no difference between patients with or without an impaired ABPI (< 0.7 mm Hg) and wound problems (p=0.20).

There was no difference in patent perforators between the injured and uninjured (p=0.39).

Occult vascular insufficiency is present but at low incidence. ABPI and Duplex-US are insensitive for predicting infection or delayed healing. The ankle fracture injury does not disrupt the local perforators. TcPO2 is sensitive and specific for predicting skin problems. Impairment of skin oxygenation is transient. Current TcPO2 technology however is impractical as a clinical tool.

After spinal cord injury (SCI) rapid muscle atrophy and extensive bone loss occur in the paralysed limbs resulting in increased fracture incidence (mostly at the epiphyses in the distal and proximal tibia and distal femur). We investigated whether re-introducing mechanical loading of the lower-limb bones in chronic SCI through exercise could induce bone formation, in accordance with Wolff’s Law.

We present cross-sectional data from the Scottish paraplegic population illustrating the time course of bone loss after SCI, and review case studies describing musculoskeletal changes following lower-limb exercise interventions in chronic SCI. Reference data were obtained from 47 subjects with SCI at neurological levels T2 to L2, ranging from 6 months to 40 years post-injury. We used peripheral Quantitative Computed Tomography (XCT3000, Stratec, Germany) to scan 4 sites in the tibia and 2 in the femur, and evaluated trabecular, cortical, and total bone data, and soft-tissue parameters. Here, we focus on trabecular bone mineral density (BMDtrab) at the epiphyses, which provides an indicator of bone integrity. The same scans were performed pre- and post-training in chronic paraplegics who undertook a period of lower-limb exercise training (body-weight-supported treadmill training (BWSTT) or electrically-stimulated leg cycle (FES-cycle) training); these results are reviewed.

The temporal pattern of bone loss is characterised by exponential decline in BMDtrab, reaching steady-state at 100 mg/cm3 in the distal tibia after 7 years and at 130 mg/cm3 in the distal femur after 3 years. A subject with incomplete SCI (18 years post-injury) showed an increase in BMDtrab in the distal tibia following 5-months BWSTT. In a separate study, subjects with complete SCI had varying responses to FES-cycle training.

Bone loss appears to plateau after 7 years post-SCI. The effectiveness of physical interventions aimed at reversing bone loss in chronic SCI seemingly depends on the details of the associated bone-loading patterns.

Over 200,000 osteoporotic fractures occur in the UK annually. Patients with fragility fractures are at highest risk of further fracture, though preventative treatment has been shown to reduce subsequent fracture incidence. In 2005, the National Institute for Health & Clinical Excellence (NICE) recommended bisphosphonates as a treatment option in women over 75 years without the need for prior DEXA scanning (Technology Appraisal Guidance 87). We prospectively reviewed the medication of such patients who were admitted to our Trauma Unit to identify if the NICE guidance was being followed.

Over a three month period between May and July 2007, 54 women over 75 years old were discharged from our Trauma Unit having sustained an osteoporotic fracture. We prospectively reviewed their medication to identify if a bisphosphonate had been commenced by the General Practitioner and their discharge letters to their General Practitioners to see if it had been suggested to start one. 7 of the 54 women (13%) were already on a bisphosphonate and were therefore excluded.

Only one (2%) of the discharge letters (written by the Orthopaedic doctor to the General Practitioner) recommended commencing a bisphosphonate. 6 of the 47 patients (13%) had been started on a bisphosphonate by the General Practitioner.

Nice guidance from 2005 is clearly not being implemented in our area. A minority of patients will have contraindications or allergies to bisphosphonates (up to 1 in 4 patients as highlighted recently by the National Osteoporosis Society). Important deficiencies in local services have been identified, particularly with respect to communication between secondary and primary care. This study lead to an education initiative to ensure the Trauma department and our local General Practitioners were aware of the NICE guidance. A second prospective audit is currently being undertaken to assess the effect on our service.

Previous studies have demonstrated higher infection rates following elective procedures on the foot and ankle as compared with procedures involving other area of the body. Previous studies also have documented the difficulty of eliminating bacteria from the forefoot prior to surgery. The purpose of the present study was to ascertain that preoperative chlorhexidine bathing provide significant local flora reduction than placebo in elective foot and ankle surgery.

From October 2005 to October 2006, a prospective study was undertaken to evaluate 50 consecutive patients undergoing planned, elective surgery of the foot and ankle. 50 patients were prospectively enrolled and randomly assigned to have preoperative footbath with Chlorhexidine Gluconate (Hibitane) (Group 1) or placebo (Group 2). Culture swabs were taken from all web spaces, nail folds, toe surfaces and proposed surgical incision sites before the preoperative antiseptics bath, during the procedures and immediately completion of surgery.

50 patients were enrolled (mean age: 42.6 years; range: 19–85; F: M = 29:21). 25 patients are assigned to each groups. 100% bacterial isolation preoperatively in both groups prior to antiseptics bathing. In group1, bacteria grew on intraoperative culture in 60% cases and 0% in immediate post-operative culture. In group 2, 96% in intraoperative swab culture and 16% in postoperative swab culture. The intraoperative swab culture bacterial count is statistically significant (p= 0.002). The postoperative swab culture bacterial count is marginally significant (p=0.055) when comparing 2 groups. No complications were recorded in both groups.

These data indicate that chlorhexidine provides better reduction in skin flora than placebo. Based of these data, we recommend the use of chlorhexidine footbath as well as the surgical preparatory agent for the foot and ankle surgery.

In January 2005, NICE published their guidelines on secondary prevention of osteoporotic fractures. This audit aims to assess our compliance with these in the outpatient setting.

The records of all new patients attending fracture clinic in a large teaching hospital, over a one month period, were reviewed. All patients who required screening or treatment for osteoporosis (females greater than 50 years old sustaining a fragility fracture) were reviewed at one year to assess compliance with the guidelines.

Of the 454 patients reviewed, 90 females over the age of 50 (19%) were identified. These were further subdivided into females between the age of 50 to 75 years (Group A, n=62) and those over 75 (Group B, n=28). The inclusion criteria was presence of a fragility fracture (Group A, n=30 and Group B, n=15). Group A was investigated with DEXA scans in only 26.7% (n=8). Of these, only six were managed as per NICE guidelines and compliant at one-year. Seven patients in Group B were subsequently treated with medical therapies, but only three were managed as per NICE guidelines and compliant. Therefore of the 45 patients included in the audit, only nine were managed appropriately at one-year (20%). One patient suffered a further fracture – who had been fully compliant with treatment.

NICE guidelines have been introduced to help the nation’s health using evidence based criteria. There has been no specific extra funding to enable the setting up of additional pathways and investigations for the targeted population. Even in a busy department where systems were implemented to follow the guidelines, the overall compliance with the pathway is less than a quarter. When new guidance is produced for healthcare, there should be advice, support and funding for their implementation.

‘Force-closed’, tapered, polished, collar-less stems, (e.g. C-stem, Exeter), are designed to subside in response to expansion of the cement/bone complex over time. Above a certain threshold, distal migration may predict medium-to-long-term failure of ‘shape-closed’ stems. However, no such threshold exists for ‘force-closed’ stems, and these may continue to migrate after 3 years. We believe that the tendency towards stabilisation 2–3 years postoperatively, could be the best predictor of good long-term performance.

Twenty OA patients (12F, mean age 66.6 years) were recruited for primary hip replacement with beaded C-stem femoral components. Tantalum marker beads were injected into the proximal femur, and stems were inserted using CMW1 cement and the latest generation cementing technique via a posterior approach: 17, and a lateral, trochanteric approach: 3. RSA X-ray examinations were performed at 1 week, 6 weeks, and at 3, 6, 12, 24 and 36 months postoperatively. The UmRSA system was used to measure and analyse the radiographs. At 36M the mean stem centroid subsidence was 1.05 mm and had levelled off to a low rate. The mean internal rotation of 2.5° at 36M had not significantly changed during the final year (p = 0.08).

At 36M the mean posterior migration of the stem centroid was 0.54 mm (rate of 0.11 mm/y) and posterior migration of the femoral head was 1.66 mm (rate of 0.25 mm/y).

At 36M the mean subsidence rate was very low and the mean posterior migration was about one third of that reported for another RSA study of the C-stem. Although the mean internal rotation was greater than that reported for the Exeter stem, there was no significant change during the final year. These low rates of migration at 3 years are consistent with the good results found in clinical studies of this femoral component.

Bone marrow derived mesenchymal stem cells are a potential source of cells for the repair of articular cartilage defects. Hypoxia has been shown to improve chondrogenesis in adult stem cells. In this study we characterised bone marrow derived stem cells and investigated the effects of hypoxia on gene expression changes and chondrogenesis.

Adherent colony forming cells were isolated and cultured from the stromal component of bone marrow. The cells at passage 2 were characterised for stem cell surface epitopes, and then cultured as cell aggregates in chondrogenic medium under normoxic (20% oxygen) or hypoxic (5% oxygen) conditions for 14 days. Gene expression analysis, glycosoaminoglycan and DNA assays, and immunohistochemical staining were determined to assess chondrogenesis.

Bone marrow derived adherent colony forming cells stained strongly for markers of adult mesenchymal stem cells including CD44, CD90 and CD105, and they were negative for the haematopoietic cell marker CD34 and for the neural and myogenic cell marker CD56. Interestingly, a high number of cells were also positive for the pericyte marker 3G5. Cell aggregates showed a chondrogenic response and in lowered oxygen there was increased matrix accumulation of proteoglycan, but less cell proliferation, which resulted in 3.2-fold more glycosoaminoglycan per DNA after 14 days of culture. In hypoxia there was increased expression of key transcription factor SOX6, and the expression of collagens II and XI, and aggrecan was also increased.

Pericytes are a candidate stem cell in many tissue and our results show that bone marrow derived mesenchymal stem cells express the pericyte marker 3G5. The response to chondrogenic culture in these cells was enhanced by lowered oxygen tension, which up-regulated SOX6 and increased the synthesis and assembly of matrix during chondrogenesis. This has important implications for tissue engineering applications of bone marrow derived stem cells.

Painful foot and ankle joints are often pointed out as an impeding factor for lack of mobility and weight reduction. There is an assumption that weight loss will occur after their surgery due to increased mobility. The current study aimed to evaluate the effect of surgery on post-operative body mass index (BMI) in patients who underwent mid-foot or hind-foot arthrodesis. Our secondary aim was to look at the effect of sex, pre-operative obesity and good pain relief (AOFAS> 80) on post-operative BMI.

All patients who underwent mid-foot and hind-foot arthrodesis between April 2005 and November 2006 were identified from the operating theatre records. Each patient’s BMI recorded pre-operatively was compared with that recorded at a minimum of 6 months postoperatively using the paired Student’s t-test.

There were 35 eligible patients. 3 patients were excluded because of multiple trauma and 1 patient died during the period of study. We had 31 patients with 33 procedures with a mean age of 61 years (range 41–80). There were 18 females and 13 males. It was found that there was a mean increase of BMI by 0.25 (95%CI of −.95 to.44; p-value=0.47). It was noted that BMI of patients in obese group (BMI> 30) increased post-operatively by 0.07 (95%CI of −1.52 to 1.66; p-value=0.92).

This study highlights the fact that there is no significant effect on BMI in obese patients after successful fusion surgery. The post-operative BMI is neither significantly affected by sex nor quality of pain relief.

The main surgical options for hallux rigidus include dorsal cheilectomy, arthroplasty and fusion. Compared to other surgical procedures dorsal cheilectomy involves relatively less bone loss, maintains joint motion and still leaves the potential for a further salvage procedure such as arthrodesis. The Manchester – Oxford Foot and Ankle Questionnaire (MOXFQ) has been endorsed by the British Foot and Ankle Society and recommended as a tool to measure surgical outcome.

The aim of this study was to prospectively follow-up patients following dorsal cheilectomy for hallux rigidus using the patient-reported outcome measure, the MOXFQ. Patients were deemed suitable for dorsal cheilectomy if they had symptoms of dorsal impingement (painful restriction of terminal dorsiflexion of the hallux), with absence of pain in the mid-range of passive movement (indicative of end stage arthritis), and dorsal osteophytes on radiographs.

Twenty five patients with a mean age of 62 years (range: 39 – 80 years) and comprising 17 females underwent dorsal cheilectomy for hallux rigidus. At a mean follow-up of 17 months (range 9–27 months), the mean MOXFQ score improved from 33/64 (95% CI: 27 – 38) pre-operatively to 9/64 (95% CI: 6 – 13) post-operatively. Eighty-four percent of patients had a clinically significant improvement in their walking domain, 68% in the social domain, and 59% in the pain domain of the MOXFQ. Four patients were deemed failures: three patients underwent subsequent arthrodesis for persisting pain, and one patient had no improvement in any domain of the MOXFQ.

In conclusion, this study has provided further evidence of the success of dorsal cheilectomy as a reliable treatment option for hallux rigidus. It has also demonstrated the sensitivity of the patient focused reporting instrument the MOXFQ in assessing surgical outcomes in foot surgery.