Introduction

Although total hip replacement (THR) has been described as the operation of the century, there is still room for improvement. There is therefore continued effort for advanced implants and bearing surfaces, moreover so, for the younger patient with a longer life expectancy and increased needs.

Objectives

This prospective case-series study aims to present the preliminary, minimum three-years, results of a novel uncemeted stem, the Leader StemÒ (Vadin Implants Ltd, London, U.K.). The Leader StemÒ is a titanium, tapered stem for immediate three-point fixation. There is a metaphyseal porous-coating with titanium microspheres for bone in-growth. It has anti-rotational ribs in the metaphyseal - diaphyseal junction to promote initial stability and a grit blasted diaphyseal region for bone on-growth. The distal tip is polished and shortened to minimize thigh pain, while the whole design and concept is one to eradicate stress shielding.

Introduction

3-D Printing with direct metal tooling (DMT) technology was innovatively introduced in the field of surface treatment of prosthesis to improve, moreover to overcome the problems of plasma spray, hopefully resulting in opening the possibility of another page of coating technology. We presumed such modification on the surface of Co-Cr alloy by DMT would improve the ability of Co-Cr alloys to osseointegrate.

Method

We compared the in vitro and in vivo ability of cells to adhere to DMT coated Co-Cr alloy to that of two different types of surface modifications: machined and plasma spray(TPS). We performed energy-dispersive x-ray spectroscopy and scanned electron microscopy investigations to assess the structure and morphology of the surfaces. Biologic and morphologic responses to osteoblast cell lines of human were then examined by measuring cell proliferation, cell differentiation (alkaline phosphatase activity), and avb3 integrin. The cell proliferation rate, alkaline phosphatase activity, and cell adhesion in the MAO group increased in comparison to those in the machined and grit-blasted groups.

Introduction

Proper acetabular component orientation is an important part of successful total hip replacement surgery. Poorly positioned implants can lead to early complications, such as dislocation. Mal-positioned acetabular components can also generate increase wear debris due to edge loading which can cause pre-mature loosening. It is essential to be able to measure post-operative implant orientation accurately to assure that implants are positioned properly.

It is difficult and potentially inaccurate to manually measure implant orientation on a post-op radiograph. This is particularly true for the immediate post-op radiograph where the patient is not as well aligned relative to the x-ray beam. However, the best time to determine if an acetabular component is mal-aligned is immediately following surgery so the patient could be taken back to the OR for immediate revision. Taking post-op CT scans is expensive and subjects the patient to increased radiation exposure, so using CT post-operatively is not done routinely. With the increased use of robotics and computer navigation at surgery there are often pre-op CT scans for total hip replacement patients. Current radiological tools do not take advantage of this pre-op CT scan for assessment of acetabular component orientation. A new software module for Mimics medical imaging software (Materialise, Leuven, Belgium) is able to overlay 3D CT data onto radiographs. We used this x-ray module to see if we could measure acetabular component orientation using the pre-op CT scan and the routine post-op x-ray that is taken immediately following total hip arthroplasty at our institution.

Methods

From a prior study, we had pre-op, and post-op CT scans of a group of twenty patients who received a total hip replacement. The post-op scan was used to measure the actual acetabular component orientation, both inclination and anteversion (Figure 1). We then measured component orientation using only the pre-op CT scan and the initial post-op x-ray using the Mimics x-ray module. We created a 3D model of the pelvis from the pre-op CT using Mimics. Then, the x-ray module was used to import the post-op radiograph into the Mimics file. Using the software, the x-ray was registered to the pre-op 3D pelvis. A 3D .stl file of the acetabular component used at surgery was then imported into the Mimics file and also registered according to the post-op radiograph (Figures 2 and 3). Once the cup and pelvis were both registered to the post-op radiograph, they were exported as .stl files and the acetabular anteversion and inclination were measured using the same method we used for the post-op scan. We then compared the results of our measurements from the post-op 3D reconstruction to the 2D overlay method to determine the accuracy of this new measurement technique.

Introduction

Osteoporotic intertrochanteric fracture (ITF) is frequent injuries affecting elderly, osteoporotic patients leading to significant morbidity and mortality. Successful prognosis including union and alignment is challenging even though initial successful reduction with internal fixation. Although many factors are related to the patient's final prognosis. Well reduction with stable fracture fixation is still the goal of treatment to improve the quality of life and decrease morbidity in patients with hip fractures, but this in turn depends on the type of fracture and bone quality. Poor bone quality is responsible for common complications, such as failure of fixation, varus collapse and lag screw cut-out, in elderly patients. Kim et al. found that the complication rate when using conventional DHS in unstable ITFs can be as high as 50% because of screw cut-out. We used the dynamic hip screws (DHS) strengthened by calcium phosphate cement (CPC) for treatment femoral intertrochanteric fracture and review the prognosis of our patients.

Materials and Methods

From January of 2011 to January of 2014, 42 patients with femoral intertrochanteric fracture underwent surgery with DHS strengthened by CPC. Comparisons were made between the DHS plus CPC group with the other patients with only DHS used in our department. All patients were followed up for an average time of 14.8(6 to 24) months. X-ray was reviewed for the conditions of union and implant failure.

Introduction

Failures in total knee arthroplasty (TKA) have been associated with overall lower limb malalignment and component malposition. Although traditional computer navigation systems improve component placement, they require fixation of the femoral and tibial reference arrays for software recognition using anchoring pins. This increases the risk of bony fracture, pin sites infection and osteomyelitis.

Aim

This study aims to evaluate the accuracy of a new hand held navigation system (BrainLAB® Dash® Navigation system) that will avoid these complications.

Background

Malposition of the glenoid component in total shoulder arthroplasty (TSA) is associated with higher strain patterns and can result in component loosening. Glenoid hardware placement and optimal size remain challenging due to the difficult joint exposure and visualization of anatomical reference landmarks during the procedure. Therefore, understanding both normal and variant patterns of glenoid anatomy is imperative for success in TSA. To better understand individual variations in glenoid morphology, this study aimed to compare the glenoid anatomy in a cohort of male and female patients from the United States (US) and Australia (AUS).

Methods

Computed tomography (CT) data were analyzed from 41 male and 35 female shoulders; 39 of which were from a US population and 37 from an AUS population. These data were used to create statistical shape models (SSM) representing the average and ±1 standard deviations of the first mode of variation of each group (Materialise, Leuven, Belgium). All measurements were performed with 3-matic computer assisted design software (Materialise, Leuven, Belgium). On each model, glenoid height was measured as the distance from the most superior to the most inferior point on the glenoid face. Glenoid width was measured as the distance from the most anterior to the most posterior point on the glenoid face. Surface area was measured as the concave surface of the glenoid face (Figure 1). Glenoid vault depth was measured in the midsection of the glenoid face.

Introduction

Persistent anterior knee pain, subluxation or dislocation of the patella as well as early aseptic loosening and increased polyethylene wear of the patella implant are common clinical problems after total knee arthroplasty (TKA) which are associated with the patellofemoral joint. In addition to patellar resurfacing, the design of the patellofemoral joint surfaces is attributed a large influence. While for patients without patella resurfacing, the native patella is sliding on the standardized femoral component and therefore the possibility of a reduced surface matching is high, patella resurfacing has been shown to decrease the joint contact area and yield to increased patellofemoral pressure. With regard to a further design optimization, the current study examined patellar biomechanics after TKA without and with resurfacing, comparing 5 differently designed patellofemoral joint surfaces of the femoral implant.

Methods

The femoral implant of the Genesis II prosthesis (Smith & Nephew) was scanned and an adaptable CAD-model was built using CATIA. Five different designs of the patellofemoral groove were created:

The tibiofemoral joint as well as patellofemoral groove path and radius remained unchanged. Rapid Prototyping was used to produce prototypes made of polyamide.

A dynamic muscle loaded knee squat was simulated on 10 fresh frozen knee specimens with an upright knee simulator. The patellofemoral pressure distribution was measured using a flexible, resistive force sensor (TEKSCAN) while tibiofemoral and patellofemoral kinematics were recorded with an ultrasonic motion tracking system (ZEBRIS). In addition, patellar stability was measured in different flexion angles on another 10 specimens using a robot (KUKA). Measurements were taken on the native knee as well as after TKA and after additional patellar resurfacing with alternating femoral implant.

Introduction

The number of total hip arthroplasties in young patients is continuosly increasing. Nowdays, the study of the materials wear, with the goal of improving the survivorship of implants, represents a fundamental subject in this kind of surgery. The role of ceramic materials in the valutation of types of wear is particularly known.

Materials and Methods

We have selected 834 patients, underwent total hip arthroplasty, in which a ceramic head was impalnted with a maximum follow up of ten years. 367 patients were males and 467 were females, operated by 14 surgeons of the same equipe of Orthopaedic and Traumatology Department. A postero-lateral approach, according to Gibson Moore, and an extrarotator tendons transosseal repair was performed.

Introduction

Highly crosslinked polyethylene (HXLPE) was clinically introduced approximately a decade and a half ago to reduce polyethylene wear rates and subsequent osteolysis. Clinical and radiographic studies have repeatedly shown increased wear resistance, however concerns of rim oxidation and fatigue fracture remain. Although short to intermediate term retrieval studies of these materials are available, the long-term behavior of these materials remains unclear.

Methods

Between 2000 and 2015, 115 1st generation HXLPE acetabular liners implanted for 5 or more years were collected and analyzed as part of an ongoing, multi-institutional orthopaedic implant retrieval program. There were two material cohorts based on thermal processing (annealed (n=45) and remelted (n=70)). Each cohort was stratified into two more cohorts based on implantation time (5 – 10 years and >10 years). For annealed components, the intermediate-term liners (n=30) were implanted on average (±SD) for 7.3 ± 1.7 years while the long-term liners (n=15) were implanted for 11.3 ± 1.8 years. For remelted components, the intermediate-term liners (n=59) were implanted on average (±SD) for 7.2 ± 1.3 years while the long-term liners (n=11) were implanted for 11.3 ± 1.2 years. For each cohort, the predominant revision reasons were loosening, instability, and infection (Figure 1). Short-term liners (in-vivo <5ys) from previous studies were analyzed using the same protocol for use as a reference.

For oxidation analysis, thin slices (∼200 μm) were taken from the superior/inferior axis and subsequently boiled in heptane for 6 hours to remove absorbed lipids that may interfere with the oxidation analysis. 3mm line profiles (in 100μm increments) were taken perpendicular to the surface at each region of interest. Oxidation indices were calculated according to ASTM 2102. Penetration was measured directly using a calibrated micrometer (accuracy=0.001mm).

Introduction

Thermally treated 1st generation highly crosslinked polyethylenes (HXLPE) have demonstrated reduced penetration and osteolysis rates, however, concerns still remain with respect to oxidative stability and mechanical properties of these materials. To address these concerns, manufacturers have introduced the use of antioxidants to quench free radicals while maintaining the mechanical properties of the HXLPE. Two common antioxidants are α-tocopherol (Vitamin-E) and pentaerythritol tetrakis (PBHP). These may be either mixed prior to consolidation, or diffused throughout the polymer after consolidation and irradiation. In vitrostudies have shown that these materials are oxidatively stable and have improved mechanical properties compared to 1st generation HXLPEs; however, few studies have investigated the in vivo performance of anti-oxidant stabilized HXLPE. The purpose of this study was to investigate the revision reasons, oxidation, and mechanical properties of retrieved short-term anti-oxidant HXLPE.

Methods

Between 2010 and 2015, 73 anti-oxidant HXLPE components were collected as a part of an IRB approved, multi-institutional retrieval analysis program during routine revision surgery. Of the seventy-three components, 30 (41%) were acetabular liners, whereas, 43 were tibial inserts. The components were fabricated from three different materials: Vitamin-E Diffused HXLPE (n=30; E1, Biomet), Vitamin-E Blended (n = 41; Vivacit-E, Zimmer) and PBHP blended (n = 2, AOX, DePuy). The hip and knee components were implanted for 0.7 ± 0.8 years (Range: 0.0–2.25 years) and 0.8 ± 1.1 years (Range: 0.0–4.5 years), respectively. Implantation time, patient weight, age, gender, and activity levels were similar between hip and knee components (Table 1).

For oxidation analysis, thin slices (∼200μm) were taken from medial condyle and central eminence of the tibial inserts or the superior/inferior axis from hip components. The slices were boiled in heptane for six hours to extract lipids absorbed in vivo. 3-millimeter FTIR line scans were taken perpendicular to the surface of interest, according to the ASTM F2102. Mechanical properties were assessed using the small punch test (ASTM F2183). Forty-three explants were available for destructive testing.

Introduction

Current techniques in total knee arthroplasty aim to restore the coronal mechanical axis to neutral. Preoperative planning has historically been based on long-leg standing films (LLSF) which allow surgeons to plan bony resection and soft tissue releases. However, LSSF can be prone to error if malrotated. Recently, patient-specific guides (PSG) utilizing supine magnetic resonance imaging (sMRI) have become an accepted technique for preoperative planning. In this study we sought to compare the degree of coronal deformity using LLSF and sMRI.

Methods

Two hundred thirty knees underwent planning for total knee arthroplasty with sMRI and LLSF. Coronal plane deformity was determined based on the femoral-tibial angle (FTA) as defined by the angle formed between a line from the center of the femoral head to the intercondylar notch and a line from the middle of the tibial spines to the middle of the ankle joint. Mechanical axis values from the sMRI were compared with values obtained from LLSF

Introduction

Three anatomic landmarks are typically used to estimate proper femoral component rotation in total knee arthroplasty: the transepicondylar axis (TEA), Whiteside's line, and the posterior condylar axis (PCA). Previous studies have shown that the presence of tibia vara may be accompanied by a hyperplastic posteromedial femoral condyle, which affects the relationship between the PCA and the TEA. The purpose of this study was to determine the relationship of tibia vara with the PCA.

Methods

Two hundred and forty-eight knees underwent planning for total knee arthroplasty with MRI. The MRI was used to characterize the relationship between the transepicondylar axis and the posterior condylar axis. Long-leg standing films (LLSF) were obtained to evaluate the medial proximal tibial angle. The MPTA is defined as the medial angle formed between a line along the anatomic axis of the tibia and a line along the tibial plateau.

Introduction

Dual Mobility (DM) implants have gained popularity for the treatment and prevention of hip dislocation, with increased stability provided by a large diameter mobile liner. However, distal regions of the liner can impinge on soft-tissues like hip capsule and iliopsoas, leading to anterior hip pain. Additionally, soft-tissue impingement may trap the mobile liner, leading to excessive loading of the liner rim, from engagement with the femoral stem, and subsequent intra-prosthetic dislocation. The hypothesis of this study was that reducing the liner profile below the equator (contoured design) can mitigate soft-tissue impingement without compromising inner-head pull-out resistance and overall hip joint stability (Fig. 1).

Methods

The interaction of conventional and contoured liners with anterior soft-tissues was evaluated in 10 cadaveric hips (5 specimens; 2 male, 3 female; age 65 ± 10 yrs; liner diameter 42–48mm) via visual observation and fluoroscopic imaging. A metal wire was sutured to the deep fibers of the iliopsoas tendon/muscle, and metal wires were embedded in the mobile liners for fluoroscopic visualization (Fig. 2). All soft-tissue except the anterior hip capsule and iliopsoas was removed, and a rope was attached to the iliopsoas to apply tension along its natural orientation.

Resistance to inner-head pull-out was evaluated via Finite Element Analysis (FEA) by simulating a full cycle of insertion of the inner head into the mobile liner and subsequent pullout. The femoral head, acetabular shell, and stem were modeled as rigid, while the mobile liner was modeled as plastically deformable. Hip joint stability was evaluated by dynamic simulations in for two dislocation modes: (A) Posterior dislocation (at 90° hip flexion) with internal hip rotation; (B) Posterior dislocation (starting at 90° flexion) with combined hip flexion and adduction. A 44 mm diameter conventional and a 44 mm contoured liner were evaluated during these tests.

Introduction

Aim of this study is to assess any differences in digital templanting accuracy of a modular short femoral stems implanted with 2 different appoaches (direct anterior and posterolateral).

Material and Methods

From December 2012 to Jenaury 2014 100 patient undergoing to a THA using the same implant with a short femoral modular stem were prospectively included in the study and divided in 2 groups according to the surgical approach. All the patients underwent to the same preoperative radiological protocol and the digital templating. The digital templating results were compared with the truly inserted implant size and a statistical analysis was carried on.

Purpose

The purpose of this study is to investigate whether traditional morphometric parameters of the femur trochlear surface are dependable to classify the severity of the trochlear dysplasia.

Methods

An automatic method to process the distal femur surface is proposed to determine anatomical landmarks and compute morphometric parameters, namely the trochlear depth(TD), the trochlear sulcus angle(SA), the lateral trochlear facet inclination(LFTI), the trochlear facet asymmetry ratio(TFAR) and the ratio between the two (lateral and medial) maximum antero-posterior sizes(CAR) routinately used to quantify trochlear dysplasia. Tests on 11 cadavers and 43 patients, affected by aspecific anterior knee pain, elucidate the role of the parameter cut-off values traditionally used in clinical practice.

Introduction

Proper alignment (tibial alignment, femoral alignment, and overall anatomic alignment) of the prosthesis during total knee replacement is critical in maximizing implant survival[7] and to reduce polyethylene wear[1]. Poor overall anatomic alignment of a total knee replacement was associated with a 6.9 times greater risk of failure due to tibial collapse, that varus tibial alignment is associated with a 3.2 times greater risk[2] and valgus femoral alignment is associated with a 5.1 times greater risk of failure[7]. To reduce this variability intramedullary (IM) instruments have been widely used, with increased risk of the fat emboli rate to the lungs and brain during TKA[6] and possible increase of blood loss[4, 5]. Or, alternatively, navigation has been used to achieve proper alignment and to reduce morbidity[3]. Recently, for distal femoral resection, inertial sensors have been coupled to extramedullary (EM) instruments to improve TKA surgery in terms of femoral implant alignment, with respect to femoral mechanical axis, and reduced morbidity by avoidance of IM canal violation. The purpose if this study is to compare blood loss and alignment of distal femoral cut in three cohorts of patients: 1 Operated with inertial based cutting guide; 2 Operated with navigation instruments; 3 operated with conventional IM instruments.

Material and methods

From September to November 2014 30 consecutive patients, eligible for TKA, were randomly divided into three cohorts with 10 patients each:x 1 “EM Perseus”, patient operated with EM inertial based instruments (Perseus, Orthokey Italia srl, Florence, Italy); 2 “EM Nav”, operated with standard navigated technique, where bone resections were planned and verified by mean of navigation system (BLUIGS, Orthokey Italia srl, Florence, Italy); 3 “IM Conv”, operated with standard IM instrumentation. All patients were operated by the same surgical technique, implanted TKA were mobile bearing PS models, Gemini (Waldemar Link, Hamburg, Germany) and Attune (Depuy, Warsaw, Indiana). Anteroposterior, lateral, and full-limb weightbearing views preoperatively and postoperatively at discharge were obtained, taking care of neutral limb rotational positioning in all patients enrolled in the study. Angles between femoral mechanical axis and implant orientation on frontal and lateral planes were measured with a CAD software (Rhinoceros 3, McNeel Europe, Rome, Italy) by two independent persons, average value was used for statistical analysis. Haemoglobin values were recorded at three time intervals: the day before surgery, at 24h follow-up and at patients discharge.

Introduction

Total Hip Arthroplasty (THA) is currently one of the most widely performed surgical procedures in clinical orthopaedic practice. Despite the recorded number of uncemented implants has steadily increased in recent years, cemented fixation still remains the benchmark in THA, accounting for most of the procedures performed nowadays. The Friendly Short is a novel cemented short-stem that grants a less invasive and more bone conservative approach due to its shortened height and innovative cementing technique. It is indicated to treat elderly patients with the aim of preserving bone diaphysis while decreasing postoperative recovery times. Its instrument set allows to optimize the cement mantle thickness via an improved pressurization and stem centralization system.

Objectives

Aim of this prospective study was to evaluate functional recovery and implant stability after THA with this cemented short-stem.

Introduction

Although total knee arthroplasty (TKA) has become a successful routine procedure in clinical orthopaedics, up to 20% of patients are not satisfied with the outcome of their surgery. Dissatisfaction in high-demand patients has been associated with the functional limitations of conventional TKA implants, as they do not recreate the natural biomechanics of the knee.

A novel knee prosthesis has been designed to replicate the natural rolling & gliding mechanism of the knee joint, aiming to restore a physiological movement whilst improving implant stability and pain-free function.

This TKR system includes 3 versions (CR, PS, KR); the KR (Kinematic Retaining) preserves the posterior cruciate ligament (PCL); the femoral component incorporates a thin anterior flange and a deep, broad trochlear groove to reduce anterior knee pain and to reproduce physiological patellar tracking without constraining the patella. The sagittal plane multiple radii of the femoral condyles (J-curve) allows the carefully designed femur to physiologically tension the collateral ligaments during the entire flexion/extension cycle. Tibial liners are also asymmetrical, presenting a concave medial shape with a saddle-like lateral shape. These asymmetric articulating surfaces have been designed to reproduce a more natural physiological roll-back and rotation of the femur over the tibia, thus reducing the sliding friction in the early phases of knee flexion. Furthermore, the roll-back motion relieves the stress from the patella and restores the physiological function of the quadriceps.

Objectives

Aim of this retrospective study was to assess the first clinical and radiographic outcomes after TKA with the Physica Kinematic Retaining (KR) knee system.

Introduction

Acetabular bone deficiency, especially proximal and lateral deficiency, is a difficult technical problem during primary total hip arthroplasty (THA) in developmental hip dysplasia (DDH). We report a configuration-based acetabular classification, a modification of the Crowe's classification, of DDH, including a definition of shallow acetabuli. We also report a new reconstruction method using a medial reduced cemented socket andadditional bulk bone in conjunction with impaction morselized bone grafting (Ad-BBG method). We aimed to evaluate usefulness of the classification and the method's clinical/radiographic outcomes.

Methods

One hundred thirty one hips of 330 THAs for DDH (40%) were defined shallow. The Ad-BBG methodwas performed on 102 hips (78% shallow hips). For the 24 remaining hips, THA was performed using the conventional interposition bulk bone grafting (Ip-BBG) (8 hips)or without bone grafting by using rigid lateral osteophyte (16 hips). Japanese Orthopaedic Association (JOA) scores and the Merle d'Aubigne and Postel (M&P) scores were used in follow-up; radiographs were analyzed retrospectively. The criteria used for determining loosening were migration or a total radiolucent zone between the prosthesis/bone cement and host bone. The follow-up period was 9.2 ± 2.6 (range, 5.0–14.0) years.

Introduction

Some patients complain ingrown pain or discomfort after implanting Co-Cr conventional endprosthesis of the hip. Some of this complaint may be attributable for effect on cartilage metabolism. It have been reported that ceramic is bioinert for biological tissue. On the other hand, metal including cobalt-chrome (Co-Cr) have some detrimental effect on biological tissue. However, there is no report concerning acetabular cartilage metabolism after hip endprosthesis implantation.

In the present study, we hypothesized that ceramic head have small detrimental effect on cartilage cell metabolism. Specific aim of the study is to compare the protein level of inflammation related cytokines, amount of hyaluronic acid (HA) in culture media, and cartilage mRNA expression in organ culture model of hip end prosthesis implanted using ceramic head and Co-Cr head.

Materials and Methods

Six acetabulum of 3 matured crossbred pig (average weight: 36 +/− 3.6kg) was retrieved. Animal experiment was performed under the rules of ethical committee of animal experiment. Average diameter of pig acetabulum was 26.3 +/− 0.6 mm. Just after sacrifice, mechanical loading using Instron testing machine with 26mm diameter of Co-Cr in right hip and Ceramic heads in left hip was performed in culture media. Ten thousand cycles of cyclic compression and rotation load (1.5kN to 0.15kN of compression and 12 degrees of rotation) to cartilage was applied at 1Hz (Figure 1).

Culture media was analyzed for protein levels of inflammation related cytokines and amount of HA. Relative quantitative reverse transcriptase-polymerase chain reaction (RT-PCR) from acetabular cartilage was performed as previously reported using specific primer sets for type II collagen, aggrecan, TNF-alpha, Interleukine-1 and 6, and MMP-1, 3, 13.

Introduction

For anatomical reconstruction in shoulder arthroplasty, it is important to understand normal glenohumeral geometry. Unfortunately, however, the details of the glenohumeral joint in Asian populations have not been sufficiently evaluated. There is a racial difference in body size, and this difference probably results in a difference in glenohumeral size.

The purpose of this study was to evaluate three-dimensional geometry of the glenohumeral joint in the normal Asian population and to clarify its morphologic features.

Methods

Anthropometric analysis of the glenohumeral joint was performed using computed tomography scans of 160 normal shoulders from healthy volunteers in age from 20 to 40 years. Using OsiriX MD, Geomagic Studio, and AVIZO software, the dimensions of humeral head width, humeral head diameter, glenoid height, glenoid width, and glenoid diameter were analyzed three-dimensionally (Figure 1). In diameter analyses, the humeral head was assumed to be a sphere and the glenoid was to fit a sphere (Figure 2–3).

Sex differences in height, humeral length, humeral head width, humeral head diameter, glenoid height, glenoid width, and glenoid diameter were compared using Mann-Whitney U tests. The correlations between sides and among the respective parameters in the glenohumeral dimensions were evaluated with Spearman rank correlation tests. The significance level was set at 0.05 for all analyses.

Introduction

The influence of the bone mineral density (BMD) on the mechanical behavior of bones can be examined using computer tomography (CT) data and finite element (FE) simulations, because the BMD correlates with the Hounsfield scale (HU) of the CT data. Therefor the material mapping strategy, which is required to assign the HU values to the FE mesh, is of crucial importance. In this study a nodal mapping strategy was analyzed concerning its sensitivity towards FE mesh parameters and an averaging of HU values from the area around the respective nodes.

Method

The FE simulation is based on CT data of a human proximal femur. Once the bone shape was reconstructed, the resulting model was meshed with quadratic tetrahedral elements in ABAQUS/CAE and all nodes were assigned an HU value from the CT data by using the respective node coordinates. In this process, the mesh density, the threshold, which could be used to exclude connective tissue and fat from the material mapping process, the considered volume around the nodes and the method of averaging were varied. The material assignment was realized by an HU value dependent, linear elastic material definition. The femur model was clamped at the level of the isthmus and a displacement of 0.5 mm was applied at the femoral head. The evaluation was based on the resulting reaction forces.

Introduction

While implant designs and surgical techniques have improved in total knee arthroplasty (TKA), approximately 20% of patients remain dissatisfied. The purpose of this study was to determine if reproduction of anatomic preoperative measurements correlated to improved clinical outcomes in TKA.

Methods

We retrospectively reviewed95 patients (106 knees) who underwent a TKA between 2012 −2013 with a minimum of one year follow-up. All patients had a pre and post-operative SF-12 and WOMAC scores. Pre and 6 week post-operative radiographs were reviewed to compare restoration of coronal plane alignment, maintenance of joint line obliquity, and maintenance of tibial varus. Coronal alignment was defined as the angle formed between the mechanical axis of the femur and the the tibia. Joint line obliquity was defined as the angle between the mechanical axis of the limb and the line which best parallels the joint space at the knee. Tibial varus was compared between the preoperative proximal lateral tibial angle and the angle formed by the mechanical axis of the tibia and tibial component postoperatively.

Introduction

Over the past several decades, numerous surgical procedures have been perfected in the inpatient hospital setting and then evolved into outpatient procedures. This has been shown to be a safe and economical transition for many orthopedic procedures. A prime example is ACL reconstruction. We report here our early experience with our initial consecutive series of outpatient UKA's done in a free standing ASC (ambulatory surgery center).

Materials and Methods

From 8/26/2008 to 5/20/12 there were 60 UKA's performed as outpatient procedures at a free standing ASC. Average patient age was 57.7 years (range of 46–69). Medical comorbidities included 22 patients with HTN and 7 with diabetes. All patients had general anesthesia with periarticular injection of the involved knee (25 cc's of Marcaine with epinephrine 1:100,000) and an intraarticular injection after closure of the capsule with 25 cc of Marcaine with epinephrine mixed with 5 cc of morphine sulfate. Patients without allergy to sulfa were given 200mg of Celebrex bid for three days and hydrocodone/acetaminophin 10/325 1–2 tabs q4 hours prn pain. Patients were discharged home when stable, ambulating with aids as needed, with length of stay ranging from 60–180 minutes (average of 85 minutes).

Introduction

The in vivo evolution of surface material properties is important in determining the longevity of bioceramics. Fracture toughness is particularly relevant because of its role in wear resistance. Some bioceramics, such as zirconia (ZrO2) undergo in vivo phase transformation, resulting in a marked reduction in toughness and commensurate increased wear. Here, we investigated the effect of accelerated aging on the surface toughness of alumina (Al2O3), zirconia-toughened alumina (ZTA), and silicon nitride (Si3N4) femoral heads, in order to identify the optimal ceramic material for in vivo implantation and long-term durability.

Materials

A newly developed Raman microprobe-assisted indentation method was applied to evaluate and compare surface fracture toughness mechanisms operative in Si3N4 (Amedica Corporation, Salt Lake City, UT, USA), Al2O3 and ZTA (BIOLOX® forte, and delta, respectively, CeramTec, GmbH, Plochingen, Germany) bioceramics. The Al2O3 and ZTA materials have long established histories in total hip arthroplasty; whereas Si3N4 has been newly developed for this purpose. The improved method proposed here consisted in coupling the “traditional” indentation technique with quantitative assessments of microscopic stress fields by confocal Raman microprobe piezo-spectroscopy. Concurrently, crack opening displacement (COD) profiles were also monitored by Raman spectroscopy. Toughness measurements were determined using both as-received and hydrothermally exposed (100–121°C for up to 300 hours) femoral heads.

Introduction

The pelvis is not a static structure. It rotates in the sagittal plane depending upon the activity being performed. These dynamic changes in pelvic tilt have a substantial effect on the functional orientation of the acetabulum. The aim of this study was to quantify the changes in sagittal pelvic position between three functional postures.

Methodology

Pre-operatively, 90 total hip replacement patients had their pelvic tilt measured in 3 functional positions – standing, supine and flexed seated (posture at “seat-off” from a standard chair), Fig 1. Lateral radiographs were used to define the pelvic tilt in the standing and flexed seated positions. Pelvic tilt was defined as the angle between a vertical reference line and the anterior pelvic plane (defined by the line joining both anterior superior iliac spines and the pubic symphysis). In the supine position pelvic tilt was defined as the angle between a horizontal reference line and the anterior pelvic plane. Supine pelvic tilt was measured from computed tomography, Fig 2.

Introduction

Appropriate acetabular cup orientation is an important factor in reducing instability and maximising the performance of the bearing after Total Hip Arthroplasty (THA). However, postoperative analyses of two large cohorts in the US have shown that more than half of cups are malorientated. In addition, there is no consensus as to what inclination and anteversion angles should be targeted, with contemporary literature suggesting that the orientation should be customised for each individual patient.

The aim of this study was to measure the accuracy of a novel patient specific instrumentation system in a consecutive series of 22 acetabular cups, each with a customised orientation.

Methodology

Twenty-two consecutive total hip replacement patients were sent for Trinity Optimized Positioning System (OPS) acetabular planning (Optimized Ortho, Sydney). The Trinity OPS planning is a preoperative, dynamic analysis of each patient performing a deep flexion and full extension activity. The software calculates the dynamic force at the hip to be replaced and plots the bearing contact patch as it traces across the articulating surface. The software modelled multiple cup orientations and the alignment which best centralised the load was chosen by the surgeon from the preoperative reports. Once the target orientations had been determined, a unique patient specific guide was 3D printed and used intra-operatively with a laser guided system to achieve the planned alignment, Fig 1. All patients received a post-operative CT scan at 3 months and the radiographic cup inclination and anteversion was measured. The study was ethically approved by The Avenue Hospital Human Research Ethics Committee, Trial Number 176.

Introduction

The role of soft tissue balancing in optimizing functional outcome and patient satisfaction after total knee arthroplasty surgery is gaining interest. This is due in part to the inability of pure alignment to demonstrate excellent functional outcomes 6. Consistent soft tissue balancing has been aided by novel technologies that can quantify loads across the joint at the time of surgery 4. In theory, compressive load equilibrium should be correlated with ligamentous equilibrium between the medial and lateral collateral ligaments. The authors propose to use the Collateral Ligaments Strain Ratio (CLSR) as a functional tool to quantify and track surgical changes in laxity of the collateral ligaments and correlate this ratio to validated functional scores and patient reported outcomes. The relationship with intra-operative balancing of compartmental loads can then be scrutinized. The benefits of varus-valgus balancing within 2o include increased range of motion 7, whereas pressure imbalance between the medial and lateral joint compartments has been linked to condylar liftoff and abnormal kinematics post-TKA 8.

Methods

The study is a prospective IRB approved clinical study with three cohorts of 50 patients each: (1) a surgical prospective study group (2) a matched control group of non-operated high function patients; (3) a matched control group of high function knee arthroplasty recipients. Standard statistical analysis method is applied. The testing of the CLSR is performed using a validated Smart Knee Brace developed by the authors and previously reported 1. The output variables consist of the maximum angular change of the knee in the coronal plane at 10 degrees of flexion produced by a controlled torque application in the varus and valgus (VV) directions. This creates measureable strain on the lateral and medial collateral ligaments, which is reported as a ratio (CLSR). The New Knee Society Score is used to track outcomes. The intra-operative balance is achieved by means of an instrumented tibial tray (OrthoSensor, Inc).

Introduction

The mechanical classical method of knee surgical instrumentation by alignment is based on built-in compromises and is considered insufficient to ensure consistent success. Soft tissue balancing is thus now seen as necessary for optimal functional outcomes and patient satisfaction. (Matsuda 2005, Winemaker 2002). The authors have previously demonstrated that balancing can be achieved through specific strategic moves. In this study, the goal was to determine the efficacy of a given surgical algorithm and to define predictors of improved outcome. The surgical target is equilibrium of contact loads. The mechanical axis remains in neutral, however subtle variation in the joint line obliquity and posterior slope are tolerated within the literature established boundaries of +/− 3 degrees and less than 10 degrees respectively.

Methods

Data was obtained from 101 consecutive primary procedures from a single surgeon (PAM) using a PCL-retaining device. For all cases the testing methodology consisted of a sag test, heel push, drawer testing at 90 degrees, and varus-valgus laxity testing at 10 degrees of flexion. Instrumented tibial trials were used to measure the contact forces on the lateral and medial sides at 10, 30, 60 and 90 degrees of flexion. Specific releases were identified and noted based on matrix profiling after each test. Re-iteration loops were enacted until balance within 15 lbs. of difference was achieved. The data was expressed as the ratio of medial/total force (total=medial + lateral), with 0.5 being equal lateral and medial forces. This was named the Contact Load Ratio (CLR). The load distribution was expressed as a scatter graph of lateral v. medial compartmental loads (Figure 1)

Background

Highly cross-linked polyethylene (HCLPE) was introduced to reduce wear and osteolysis in total hip arthroplasty (THA). There is no reported data regarding wear rates and clinical performance of Crossfire HCLPE (Stryker, Mahwah, New Jersey) in young and active patients. The purpose of this prospective study is to assess minimum 10-year wear rates and survivorship of Crossfire in young and active patients.

Material and Methods

Between January 2001 to December 2003, 52 consecutive THAs (43 patients; 26 males and 17 females), 55 years and younger, with an average University of California Los Angeles activity (UCLA) score of 7.3 ± 1.5 (5 – 10) at the time of surgery were prospectively followed. The mean age of patients was 47.4 ± 7.8 years old (range 24 to 55 years). Indication for surgery included osteoarthritis in all cases. All operations were performed by the senior surgeon via a posterolateral approach. All components were non-cemented SecurFit femoral stem, 28 mm Cobalt-Chromium (Co-Cr) femoral head, and Trident PSL cup with Crossfire HCLPE acetabular liner (Stryker, Mahwah, New Jersey). At minimum 10-years follow-up (mean 11.5 ± 0.94 years), wear rates were assessed using the Roman software. Hospital for Special Surgery (HSS) scores and survivorship data were analyzed.

Background

Wear and osteolysis are major contributors, which limit the durability of total hip Arthroplasty (THA) and ultimately cause it to fail. Efforts were made to decrease wear by highly cross-linked polyethylene (HXLPE) and using ceramic bearings.

Questions/Purposes

The purpose of this study is to analyze and compare the five year performance of large sized (32mm and 36mm) ceramic and metal heads on X3 HXLPE (Stryker, Mahwah, NJ, USA).

Introduction

Accurate and reproducible cup positioning is one the most important technical factors that affects outcomes of total hip arthroplasty (THA). Although Lewinnek's safe zone is the most accepted range for anteversion and abduction angles socket orientation, the effect of fixed lumbosacral spine on pelvic tilt and obliquity is not yet established.

Questions:

Material and Methods

Between July 2011 and October 2011, 68 consecutive unilateral THAs were implanted in 68 patients with a mean age of 71 ± 6 years old. Radiographic evaluation included standing anteroposterior (AP) and lateral pelvic radiographs, and sitting lateral pelvic radiograph, measuring lumbosacral angle (LSA), sacral angle (SA), and sagittal pelvic tilt angle (SPTA). Computer generated 3D pelvis models were used to analyze the correlation between different pelvic tilts and acetabular cup orientation in abduction and anteversion.

Introduction

Acetabular fixation is one of the major factors affecting long-term longevity and durability of total hip arthroplasty (THA). Limited data exist regarding mid-term performance of modern non-cemented rim-fit cups with HA coating. The aim of this study was to assess the minimum 5 year clinical and radiographic performance of PSL cups. Therefore we retrospectively analyzed results of this component in patients that had adequate followup from a prospective institutional database.

Materials and Methods

A retrospective analysis of a prospective database was performed to identify patients that underwent non-cemented THA between 2003 and 2007. 223 primary THA (210 patients) were performed by single surgeon via posterolaeral approach using a grit-blasted, HA coated rim-fit design and highly cross-linked polyethylene and were followed with minimum 5 years. The mean age was 62.5 years ± 10.8. The majority of the stems were non-cemented (87%) and the majority of the femoral heads were metal (75%), 22- or 28-mm diameter. 72% of the cups were solid and 28% were multi-hole. Clinical assessment included the Hospital for Special Surgery (HSS) hip score [18] at final follow-up, and Kaplan-Meier survivorship.

All patients received pre- and post-operative anteroposterior (AP) weight bearing pelvis radiograph as well as a false profile view of the hip. Cup positioning was analyzed using the EBRA software (Einzel-Bild-Roentgen-Analysis; University of Innsbruck, Innsbruck, Austria) for functional abduction angle, anteversion, and cup migration. Osseointegration was assessed on the DeLee and Charnley's zones on both AP and false profile views. Osseointegration was defined based on the following characteristics:

Linear and rotational migration was defined as > 3 mm or > 5°change in the cup position, respectively, as measured on serial radiographs. Any changes in cup position or presence of circumferential radiolucencies were considered as loosening.

Background

Tranexamic acid (TXA) is a lysine analog that has been shown to reduce intra-operative blood loss in total joint replacements. Effect of TXA in morbid obese patients has not been established. The aim of this study was to evaluate the effect of TXA on change of haematocrit (HCT) and packed RBC (PRBC) blood transfusion rate in our institution, especially in morbid obese patients.

Methods

Between January 2014 and December 2014, 216 primary and revision hip and knee arthroplasty were identified from our prospective institutional database. All cases were performed by two adult reconstruction specialists. All primary total hip arthroplasties (THA) were non-cemented and all primary total knee arthroplasties (TKA) were cemented with similar implant and technique. Use of TXA in our institution was initiated on August of 2014. TXA was given intravenously (IV) as one gram prior to incision and one gram at the time of femoral preparation in THA or cementation in TKA, not exceeding 10mg/kg. In cases where IV TXA was contraindicated, topical was used. We analyzed pre- and post-operative hematocrit and transfusion rate. Criteria for transfusion was HCT < 25 or Hb < 9. 72 patients (33%) were considered morbid obese with body mass index (BMI) ≥ 35.

Background

Post-operative deep venous thrombosis (DVT) and subsequent pulmonary embolism (PE) remain a serious complication after total joint replacement. Although with modern chemical and mechanical prophylaxis and rapid rehabilitation the rate of symptomatic DVT and PE has reduced, isolation of pre-operative DVT, specially in patients with prior history of DVT remains a challenge. The aim of this study was to assess the use of pre-operative dopplers as a tool to detect and identify prior DVT in patients undergoing total joint replacement.

Methods

Between January 2014 and December 2014, 211 elective primary and revision hip and knee arthroplasty were identified from our prospective institutional database. All cases were performed by two adult reconstruction specialists. All primary total hip arthroplasties (THA) were non-cemented and all primary total knee arthroplasties (TKA) were cemented with similar implant and technique. Prior to July 2014, only patients with prior history of DVT or PE underwent pre-operative dopplers. From July 2014, all cases underwent routine pre-operative doppler screening.

All patients with clinical symptoms of calf pain underwent post-operative dopplers. Patients were followed for a minimum of 3 month post-operatively. All emergency room (ER) visits for role out DVT were identified. No patient was lost to follow.

Introduction

Reducing readmissions after total joint arthroplasty (TJA) is challenging. Pre-operative risk stratification and optimization pre surgical care may be helpful in reducing readmission rates after primary TJA. Assessment of the predictive value of individual modifiable risk factors without a tool to properly stratify patients may not be helpful to the surgical community to reduce the risk of readmission. We developed a scoring system: Readmission Risk Assessment Tool (RRAT) as part of a Perioperative Orthopaedic Surgical Home model that allows for risk stratification in patients undergoing elective primary TJA at our institution. We analyzed the relationship between the RRAT score and readmission following primary hip or knee arthroplasty.

Methods

The RRAT, which is scored incrementally based on the number and severity of modifiable comorbidities was used to generate readmission scores for a cohort of 207 readmitted and 2 cohorts of 234 (random and age-matched) non-readmitted patients each. Regression analysis was performed to assess the strength of association between individual risk factors, RRAT score and readmissions. We also calculated the odds and odds ratio (OR) at each level of RRAT score to identify patients with relatively higher risk of readmission.

Background

Total hip arthroplasty (THA) is one of the most successful surgical procedures ever performed. Nevertheless if procedure is performed by high or low volume surgeons; more than 50% of cups are still placed out of the safe zone, which is connected to lower survival rate of the prosthesis. The idea was to develop an imageless navigation system for safe and accurate positioning of the cup in THA procedures, without a need of any preoperative computer tomography (CT) or magnetic resonance imagining (MRI).

Methods

The validation of the system was approved by National Ethics Committee. The committee allowed the validation on 10 patients who all signed the agreement for participation in the study. Unselected patients undergoing THA were included. All patients had had performed preoperative x-rays of pelvis and hips for standard preoperative planning. Immediately before skin incision, anterior pelvic plane (APP) was defined with help of specially developed electromagnetic navigation system (Guiding Star, E-Hip module, Ekliptik d.o.o., Ljubljana, Slovenia) and specificaly designed hardware tool which is essential for accurate APP determination [Fig.1]. In all patients THAs were performed through direct lateral approach and all implanted components (Allofit S cup and Alloclassic stem, Zimmer Inc., Warsaw, Indiana, USA) were implanted with freehand technique according to preoperative plan. After placement of the cups their inclination and anteversion angles were determined with aforementioned navigation system [Fig. 2]. The day after surgery, low dose CT scans of pelvises of operated patients were performed and DICOM format files were up-loaded into EBS software (Ekliptik d.o.o., Ljubljana, Slovenia), a multipurpose application for perioperative planning, measuring and constructing where virtual copies of pelvises were generated. On virtual pelvises the position of the cups was measured by independent person [Fig.3]. Measurements were compared, statistically analysed and the deviation calculated with root mean square error (RMSE) method. Afterwards the average error (eaver) and standard deviation (σ) between intraoperatively determined and postoperatively measured angles were calculated.

Introduction

Ankle arthrodesis is a common treatment for destroyed ankle arthrosis with sacrificing the range of motion. On the other hand, total ankle arthroplasty (TAA) is an operation that should develop as a method keeping or improving range of motion (ROM); however, loosening and sinking of the implant have been reported in especially constrained designs of the implant. The concept of FINE TAA is the mobile bearing system (Nakashima Medical Co., Ltd, Okayama Japan) that can reduce stress concentration to implants. The purpose of this study is to evaluate the short-term results of FINE TAA.

Objectives and Methods

We performed FINE TAA for osteoarthritis (OA) (2 ankles of 2 patients) and rheumatoid arthritis (RA) (4 ankles of 3 patients). All patients were female. The mean age of the patients was 71.4 years old at the operation. The mean follow-up period was 32.6 (range, 18–55) months. All patients were assessed for Japan Orthopedic Association (JOA) score and ROM in plantar flexion and dorsiflexion at the point of pre-operation and final follow-up. We evaluated radiolucent line, subsidence, and alignment of implants at the latest follow-up.

Introduction

Total hip arthroplasty (THA) is becoming a common procedure because it dramatically relieves the patient's pain. Accordingly, young patients who hope to take THAs are also increasing. The results of THAs in the young patients have historically shown relatively poor survivorship. However several improvements of components may promise good long term results in active young patients. There was no consensus about the appropriate time for performing THA. The purpose of this study is to review the results of THAs younger than 40 years.

Material and methods

A retrospective review of 14 primary THAs in 12 patients was conducted. The mean age was 27.0 (range 17–30). Ten were female (83%) and 2 were male (17%). The average follow –up period was 38.3 months (range 18–64). All operations were performed using direct anterior approach (DAA). All patients were allowed full weight bearing as tolerated in the immediate postoperative periods. All were cementless THA and the articulation bearing were ceramic/ceramic in 5 hips (33.3%), metal/highly cross linked polyethylene in 8 hips (53.3%), and ceramic/ highly cross linked polyethylene in 2 hips (13.3%). All patients were followed clinically and radiographically. Patients were evaluated at 4,6,12 weeks and each year postoperatively. Patients were allowed sports at 3 months postoperatively without limitations.

Introduction

The decreased bone mass or local osteoporosis at the proximal femur is often recognized in patients of rheumatoid arthritis (RA). In total hip arthroplasty (THA), the cancellous bone will be lost when rasping technique is applied for the preparation of stem insertion. In addition, cutting or elongation for contracted muscles around the hip joint can be required to insert the stem. To avoid these problems, the non-broaching, non-rasping impaction technique for the stems was applied in THA for the patients with RA. We report clinical and radiographic results of this method.

Materials and Methods

In surgery, the femoral neck was cut and prepared without using a box chisel, reamer or broaches, instead, a series of trial stems were used with the method of impaction technique. After impaction of cancellous bone with the final size of the trial stem, the stem is fixed by bone cement without taking any cement mantle. Full weight bearing was allowed for all patients from the next day of the surgery. We investigated short-term clinical and radiographic results and the incidence of complication that was related to this technique. Post-operative radiological results with the minimum follow-up of 12 months after surgery were analyzed in 31 joints (25 cases) with this technique. The mean age at the time of surgery was 66.3 years (46∼82). The mean duration after surgery was 62 months (14∼108).

Background

External fixation for a fracture-dislocation to a joint like the elbow, while maintaining joint mobility is currently done after identifying the center of rotation under X-ray guidance, when applying either a mono-lateral or a circular fixator.

Current treatment

using the galaxy fixation system by Orthofix, the surgeon needs to correctly identify the center of rotation of the elbow under X-ray guidance on lateral views. If the center of rotation of the fixator is not aligned with that of the elbow joint, the assembly will not work, i.e. the elbow will be disrupted on trying to achieve flexion or extension movements.

Figures (A, B, C and D) summarize the critical steps in identifying the centre of rotation (Courtesy of Orthofix Orthopedics International).

Purpose

The results of ceramic-on-ceramic (CoC) bearing surfaces in primary total hip arthroplasty (THA) were well known. However, it was not known in revision THA. The purpose of this study is to report the results of revision THA with ceramic articulation.

Materials and Methods

112 revision THAs with ceramic articulation were evaluated. The mean age at the time of surgery was 58.3 years (28 to 97). The mean duration of the follow-up periods was 6.4 years (2 to 11.8 years).

Introduction

We sought to determine the 10-year survivorship of single-radius, posterior-stabilized total knee arthroplasty (TKA) in Asian patients. We also aimed to determine whether the long-term clinical and radiographic results differed between patients with and without patellar resurfacing.

Materials and Methods

This retrospective study included 148 (115 patients) consecutive single-radius, posterior-stabilized TKAs. Ten-year survivorship analysis was performed using the Kaplan-Meier method with additional surgery for any reason as the end-point. Furthermore, long-term clinical and radiographic results of 109 knees (74%; 84 patients) with more than a 10-year follow-up were analyzed. Ten-year survivorship and long-term outcomes after surgery were determined, and outcomes were compared between patients with and without patellar resurfacing.

Background

The purpose of this study is to report the outcome of navigation-assisted cruciate-retaining total knee arthroplasty (TKA) using one type of cemented, second-generation, floating-platform (FP), mobile-bearing system.

Methods

We retrospectively reviewed 42 patients (51 knees) who underwent cruciate retaining TKAs using e.motion-FP prostheses under navigational guidance. The preoperative diagnosis was osteoarthritis in all knees except one rheumatoid arthritis. There were 2 men (2 knees) and 40 women (49 knees) with a mean age of 64.0 ± 4.7 years (range, 51 – 76 years) at the time of index surgery. The mean follow-up was 120.0 months (range, 106 – 126 months). Clinical and radiographic results as well as mechanical survival rate of this type prosthesis were investigated at a mean follow-up of 10 years.

Introduction

Partial meniscectomy, a surgical treatment for meniscal lesions, allows athletes to return to sporting activities within two weeks. However, this increases knee joint shear stress, which is reported to cause osteoarthritis. The volumes and locations of partial meniscectomy that would result in a substantial increase in knee joint stress is not known. This information could inform surgeons when a meniscus reconstruction is required.

Aim

Our aim was to use a previously validated knee finite element (FE) model to predict the effects of different volumes and locations of partial meniscectomy on cartilage shear stress. The functional point of interest was at the end of weight acceptance in walking and running, when the knee is subjected to maximum loading.

Background

Performing total knee replacement needs both bony & soft tissue consideration. Late John Insall advocating spacer blocks with concept of balanced & equal flexion – extension Gap. Although we usually excise both ACL & PCL, still it is possible to retain more soft tissue. Both PCL retaining & sacrificing Require intact collaterals for stability. Superficial MCL & LCL should be preserved, if possible. After PCL removal the following advantages could obtain: More correction of fixed varus or valgus deformity, More surgical exposure. but there are no proved disadvantages like; increasing in stress & loosening of bone-cement-prosthesis interface, specific clinical difference in ROM, forward lean during stepping up, proprioception inferiority. In other hand over tight PCL cause excessive rollback of tibia & knee hinges open, preventing flexion (booking), and Severe posteromedial poly wear in poor balance PCL might be happened. Mid range laxity when Post. Capsule is tight, even with correct tensioning in full extension & 90 degree flexion, may occur (and secondary collateral ligaments imbalance throughout ROM). There is a major effect of capsular contracture in coronal mal alignment with flexion contracture. Full MCL releases not only correct fixed varus but also open the medial space in flexion. MCL & post. Capsule has combined valgus resistant effect in extension. PCL release increase flexion gap more, May be necessary to release something that affect extension gap as compensated balancing (Post.medial capsule). Any flexion contracture need to posterior capsulotomy & post. Condyle osteophyte removal before femoral recut. So it is possible to perform posteromedial capsulotomy prior to superficial MCL release.

Method

From May 2009 to June 2013, 219 TKA (165 patient) (bilateral in 54 patients, simultaneous bilateral in 5 patients) with primary DJD and varus deformity of knees were operated by myself with joint replacement. Most patients had some degree of varus correction in flexion, passively. The varus angle was less than 25*, means mild to severe but not decompensate. 46 patients had some degree of patella baja. For soft tissue balancing during Total knee arthroplasty I consider the following steps; Medial capsule & deep MCL release, PCL release, Posteromedial capsulotomy, semimembranous release, Superficial MCL release, Pes anserinous release. Post.medial capsulotomy was done in all cases. The Average Age was 65.47 years, 131 patients (177 knees) were female (79.3%) and five of them had bilateral TKA simultaneously. Lt Knee was operated in 94 cases (42.9% of 219). Spinal anesthesia was applied in 54.3% (119 patients) & epidural anesthesisa in 5 % (13 cases). 14 knees were operated with MIS technique and 205 knees with Standard medial parapatellar incision. Semi membranous release was necessary in 72 knees (33 pure=15%, without S.MCL release). S.MCL release was mandatory in 39 (17.8 %) knees for checking balanced medial and lateral subtle laxity (playing), I have used simple blade with 1 & 2 mm thickness in each ends for younger patients, and the other one with 3&4 mm thickness in elder cases.

Introduction

Failure of total knee replacements due to the generation of polyethylene wear debris remains a crucial issue in orthopedics. Unlike the hip, it is difficult to accurately determine knee implant wear rates from retrieved components. Several studies have relied on thickness measurements to estimate penetration, but the complicated geometry of contemporary tibial liners poses a challenge to accurately assess wear. In this study we address the question whether linear penetration can serve as a surrogate measure for volumetric material loss.

Methods

Eighty-one retrieved UHMWPE NexGen cruciate-retaining tibial liners (Zimmer, Warsaw, IN) with an average time in situ of 5.27±2.89 years were included in the study. Metrology data for the surfaces of the tibial liners were obtained with a coordinate measuring machine (OGP, Rochester, NY). Using a laser scanner with two micrometer depth accuracy, at least 400,000 measurement points were taken by investigator #1. Areal thickness changes were mapped for the lateral and medial sides with the help of an autonomous mathematical reconstruction algorithm and volume loss was calculated based on wear scar area and local thickness change. Investigator #2, blinded from these results, measured the minimum thickness of the medial and lateral tibial plateau using a dial indicator with a spherical tip radius of 3mm. Twenty-three short term retrievals (3 to 4 per implant size), removed due to infection and without any signs of wear, served as “unused” reference. Linear penetration was then calculated by subtracting the minimum thickness of each plateau from the average thickness of the reference components.

Introduction

Hip Resurfacing Arthroplasty (HRA) has been performed in the United States for over 10 years and is an alternative to standard Total Hip Arthropastly (THA). It is appealing to younger patients with end stage osteoarthritis who seek to maintain active lifestyles. Benefits of HRA versus THR include a larger femoral ball size, potential to return to impact activities, decreased dislocation rates, and restoration of normal hip biomechanics. Patients ≤50 years old are a particularly challenging patient group to treat with THA because of their young age and high activity level, and as such, are well-suited for HRA. However, there are limited reports in the literature about clinical, radiographic and functional outcomes for this patient cohort. We present results of a clinical investigation at our institution for this patient cohort with minimum 5-year follow up, including long term survivorship and outcome scores.

Methods

HRA, using the Birmingham Hip Resurfacing (BHR), was performed for 538 procedures between 2006–2009 by a single surgeon at a United States teaching hospital. After Institutional Review Board approval, medical and radiographic study records were retrospectively reviewed. Harris Hip Scores (HHS) were routinely collected. Patients who had not returned for follow-up examination were contacted by telephone for information pertaining to their status and implant, and a modified HHS was also administered. A Kaplan Meier survival curve was constructed to evaluate time to revision. Statistical analysis was performed (SAS version 9.3; SAS Institute, Cary, NC).

Introduction

Patients presenting with osteoarthritis as late sequelae following pediatric hip trauma have few options aside from standard Total Hip Replacement (THR). For younger more active patients, Hip Resurfacing Arthroplasty (HRA) can be offered as an alternative. HRA has been performed in the United States over the past decade and allows increased bone preservation, decreased hip dislocation rates versus THR, and potential to return to full activities.

Patients presenting with end-stage hip arthritis as following prior pediatric trauma or disease often have altered hip morphology making HRA more complicated. Often Legg-Calve-Perthes (LCP) patients present with short, wide femoral necks, and femoral head distortion including coxa magna or coxa plana. There often can be acetabular dysplasia in conjunction with the proximal femoral abnormalities.

Slipped Capital Femoral Epiphysis (SCFE) patients have an alteration of the femoral neck and head alignment, which can make reshaping the femoral head difficult. In particular, the femoral head is rotated medially and posteriorly, reducing the anterior and lateral offset.

We present a cohort of 20 patients, with history of a childhood hip disorder (SCFE or LCP), who underwent HRA to treat end-stage arthritis. Fifty percent had prior pediatric surgical intervention at an average age of 11.

Method

After Institutional Review Board approval, data was reviewed retrospectively on patients with pediatric hip diseases of SCFE and LCP who underwent HRA using the Birmingham Hip Resurfacing (BHR) by a single orthopaedic surgeon at a teaching institution. Harris Hip Scores (HHS), plain radiographs and blood metal ion levels were reviewed at routine intervals (12 months and annually thereafter). Those who had not returned for recent follow-up were contacted via telephone survey for a modified HHS.

Introduction

Temporary use of antibiotic-impregnated polymethylmethacrylate (PMMA) bone cement spacers in two-stage revisions is considered to be standard of care for patients with a chronic infection of a joint replacement. Spacers should be wear resistant and load-bearing to avoid prolonged immobilisation of the patient and to reduce morbidity.

Most cement spacers contain barium sulphate or zirconium dioxide as radio-opaque substrate. Both are quite hard materials that may negatively influence the wear behaviour of the spacer.

Calcium carbonate is another radio-opaque substrate with lower hardness potentially increasing the wear resistance of the spacer materials.

The purpose of the study was to compare a prototype PMMA knee spacer (calcium carbonate loaded) with a commercially available spacer (containing barium sulphate) regarding the wear performance and particle release in a knee wear simulator.

Material and Methods

Spacer K (TECRES, Italy) was used as barium sulphate (10%) containing spacer material. A prototype material (Heraeaus Medical, Germany) with 15% calcium carbonate was compared. Both were gentamicin impregnated, ready-made for clinical application (preformed) and consist of a tibial and a femoral component.

Force-controlled simulation was carried out on an AMTI knee simulator. The test parameters were in accordance to ISO 14243–1 with a 50% reduced axial force (partial weight bearing). Tests were carried out at 37 °C in closed chambers filled with calf serum. Tests were run for 500,000 cycles at a frequency of 1 Hz. For wear analysis, gravimetric wear measurements according to ISO 14243–2 and wear particle analysis according to ASTM F1877–05 were performed.

Introduction

Taper corrosion has been identified to be major problem in total hip replacement during the past years. Patients may suffer from adverse local tissue reactions (ALTR) due to corrosion products that are released from modular taper connection. So far, the mechanism that leads to taper corrosion in taper connections is not fully understood. Some retrieval studies tried to correlate implant related design parameters to the incidence and the severeness of taper corrosion. For example Kocagöz et al.[1] have not seen an influence of the taper clearance to taper corrosion. Hothi et al.[2] showed that shorter and rougher tapers increase taper corrosion. One limitation of retrieval studies may be that the analysed tapers are used and may have been altered during in vivo service. Beside the effect of taper corrosion many surgeons are not aware that the tapers may vary among different manufactors. With our study we want to provide taper related data that may be used for comparison and correlation (e.g. retrieval studies). Therefore we aimed to assess and compare geometric and topographic design parameters of currently available hip stem tapers from different manufacturers.

Material

For comparison well established cementless hip stems made of titanium alloy were choosen. All of them have a 12/14-taper. The analysed implants are shown in Fig. 1. As geometrical parameters the taper angle, the opening taper diameter and the taper length were measured using a coordinate measuring machine (CMM) (MarVision MS 222, Mahr, Göttingen, Germany; accuracy: ±2.3 µm). Several topographical parameters (e.g. Ra, Rz, etc.) were determined using a tactil roughness measurement instrument (Perthometer M2, Mahr, Göttingen, Germany; accuracy: 12 nm). Three independent samples of each taper were measured five times.

Introduction

Modern hip replacements all have encapsulated the design concept of proximal modularity. The factors contributing to the increased wear and corrosion at the taper junction are trunnion geometry, surface characteristics, head size, impaction forces, and material coupling. This study maps the inferior and superior region of the trunnion and bore to provide a visual identification of the corrosion severity. The corrosion/wear generated inferiorly and superiorly at the bore and trunnion will be quantified to understand how corrosion is affected by mechanical stresses in relation to anatomical orientation.

Methodology

Three neck tapers generated from bar stock containing a threaded trunnion Ti-6Al-4V and 3× 32mm femoral heads (Co-Cr-Mo) with a +4 offset manufactured by Signature Orthopaedics were used within this study. Rectangular Rozzette strain gauges (Tokyo Sokki Kenkyujo Co., Ltd.) were adhered onto the inferior and superior sections of the neck section. The tapers were fatigued in accordance to ISO 7206 at 5Hz for 5 million cycles at 37 degrees Celsius in phosphate buffered saline. The tapers were sectioned from the center of the femoral head to split both trunnion and bore into superior and inferior components. SEM imaging of all surface areas for each component, per taper (4) was done under ×100 magnification. The images were used to quantify the corrosion present across the surface area using a MATLAB based program called Histomorph. To obtain a visual observation of the variation of corrosion across the bore and trunnion the proximal, medial, and distal regions were mapped together for both the superior and inferior sections.

Introduction

The possibility of corrosion at the taper junction of hip replacements was initially identified as a concern of generating adverse reactions in the late 1980s. Common clinical findings of failure are pain, clicking, swelling, fluid collections, soft tissue masses, and gluteal muscle necrosis identified intra operatively.

Methodology

The joint replacement surgery was performed utilizing a posterior approach to the hip joint. The data from all surgical, clinical and radiological examinations was prospectively collected and stored in a database. Patients were separated into two groups based on bearing material, where group 1 had a CoC bearing and ABG modular stem whilst group 2 had a MoM bearing and SROM stem, with each group having 13 cases. Pre-operative revision surgery and post-operative blood serum metal ion levels we collected. Cup inclination and anteversion was measured using the Ein-Bild-Roentgen-Analyse (EBRA) software. A range of 2–5 tissue sections was examined per case. 2 independent observers that were blinded to the clinical patient findings scored all cases. The tissue grading for the H&E tissue sections were graded based on the presence of fibrin exudates, necrosis, inflammatory cells, metallic deposits, and corrosion products. The corrosion products were identified into 3 groups based on visible observation and graded based on abundance. A scanning electron microscope (SEM) Hitachi S3400 was used to allow for topographic and compositional surface imaging. Unstained tissue sections were used for imaging and elemental analysis. X-Ray diffraction was the analytical technique used for the taper debris that provided identification on the atomic and molecular structure of a crystal.

Introduction

Cementless devices can be designed with varying surface treatments with the hope of achieving osseointegration. The surface finish dictates the interaction, adhesion and growth of bone therefore it is an important parameter that be measured and compared. The surface topography of a material can be viewed both microscopically and macroscopically. Surface microtopography focuses on the peaks and valleys where deviations in the characteristics of the size and spacing of these features determine the variability between surface topography. The most common parameter used worldwide to describe surface roughness is the arithmetic average height (Ra). The definition of Ra is the absolute deviation of the surface irregularities from a mean line across the sampling length given by the equation shown in figure 1.

Many techniques can be used to relate to surface characteristics of materials, with the common two options revolving around contact and non-contact methods. These techniques are expensive and are limited in detecting the interaction of implantable devices at a macroscopic level. This study sought to develop a method to determine the surface roughness and characterise implants based on cross sectional images and scanning electron microscopy.

Method

The profile of 6 trunnions from a total hip replacement was obtained in x and y coordinates along a set length using a profilometer. A custom program to calculate the Ra of the material was created using a mathematical program (MATLAB). Each material profile was inputted into a mathematical program to provide the surface roughness of the material. The surface parameters were initially obtained from a surface analyser to determine the accuracy of the program.

Introduction

To achieve well aligned and balanced knee is essential for the post-operative outcome in total knee arthroplasty (TKA). Gap balancing technique can adjust the bone cut depending on the soft tissue balance in addition to soft tissue releases. Therefore, gap balancing technique would be more advantageous in soft tissue balance comparing to measured resection technique (MRT) in which soft tissue balancing relayed on soft tissue releases alone. Nevertheless, the influence of surgical technique on the post-operative knee stability has not been fully investigated.

Objective

We introduced a new surgical technique (medial gap technique: MGT) according to modified gap technique regarding medial knee stability as important. The intra-operative soft tissue balance and post-operative knee stability were compared between MGT and MRT in posterior-stabilized (PS) TKA for varus type osteoarthritic knees.

Introduction

Cup malposition in hip arthroplasty and hip resurfacing is associated with instability, accelerated wear, and the need for revision. The current study assesses the validity of intraoperative assessment using a specialized software to analyze intraoperative radiographs.

Methods

Cup orientation as measured on intraoperative radiography using the RadLink Galileo Positioning System was assessed in 10 patients. These radiographs were measured by personnel trained to support the system. The results were compared to cup orientation measured by CT. Cup orientation on CT was measured by first identifying the Anterior Pelvic Plane Coordinate system landmarks on a 3D surface model. A multiplanar reconstruction module then allowed for the creation of a plane parallel with the opening plane of the acetabulum. The orientation of the cup opening plane in the AP Plane coordinate space was then calculated. The same definition of cup orientation was used for both methodologies.

Introduction

Navigation of acetabular component orientation is still not commonly performed despite repeated studies that show that more than ½ of acetabular components placed during hip arthroplasty are significantly malpositioned1. The current study uses postoperative CT to assess the accuracy of a smart mechanical navigation instrument system for cup alignment.

Patients and Methods

Twenty nine hip replacements performed using the HipXpert Navigation System had post-operative CT studies available for analysis. These post-operative CT studies were performed for pre-operative planning of the contralateral side, one to three years following the prior surgery. The patients included 17 men and 11 women.

An application specific software module was developed to measure cup orientation using CT (HXR Application 1.3 Surgical Planning Associates Inc., Boston, Massachusetts). The method involves creation of a 3D surface model from the CT data and then determination of an Anterior Pelvic Plane coordinate system. A multiplaner image viewer module is then used to create an image through the CT dataset that is coincident with the opening plane of the acetabular component. Points on this plane are input and then the orientation of the cup is calculated relative to the AP Plane coordinate space according to Murray's definitions of operative anteversion and operative inclination. The actual cup orientation was then compared to the goal of cup orientation recorded when the surgery was performed using the HipXpert navigation system for acetabular component alignment.

INTRODUCTION

Evolving payment models create new opportunities for assessment of patient care based on total cost over a defined period of time. These models allow for analyses of economic data that was previously unavailable and well beyond our familiar studies which typically include length of stay, surgical complications, and post-operative clinical and radiographic assessments. In the United States, the new Federal program entitled TheBundled Payment for Care Initiative created new opportunities for the assessment of surgical interventions. The purpose of the reported study was to assess the total reimbursement for care as a function of surgical technique in primary total hip arthroplasty (THA).

METHODS

The total reimbursement for services performed following primary THA for patients insured by Medicare was analyzed for a group of patients at a single institution during the fiscal years of 2013 and 2014. The population included data on 356 patients who had surgery performed by seven surgeons who used the same pre-operative education, OR, PACU, PT, nursing, and case management. A total of 38 “pre-selected” patients underwent THA by an anterior exposure, 219 had surgery performed by a posterior exposure, and 99 had surgery performed by the superior exposure utilizing mechanical surgical navigation (HipXpert System, Surgical Planning Associates, Boston, MA). Reimbursement for all in-patient and out-patient services performed over the initial 90-day period from sugeical admission was compared across surgical techniques. Reimbursement includes the sum of all payments including the hospital, physicians, skilled nursing facilities, home care, out-patient care, and readmission.

INTRODUCTION

Modular knee implants are used to manage large bone defects in revision total knee arthroplasty. These implants are confronted with varying fixation characteristics, changes in load transfer or stiffen the bone. In spite of their current clinical use, the influence of modularity on the biomechanical implant-bone behavior (e.g. implant fixation, flexibility, etc.) still is inadequately investigated.

Aim of this study is to analyze, if the modularity of a tibial implant could change the biomechanical implant fixation behavior and the implant-bone flexibility.

MATERIAL & METHODS

Nine different stem and sleeve combinations of the clinically used tibial revision system Sigma TC3 (DePuy) were compared, each implanted standardized with n=4 in a total of 36 synthetic tibial bones. Four additional un-implanted bones served as reference. Two different cyclic load situations were applied on the implant: 1. Axial torque of ±7Nm around the longitudinal stem axis to determine the rotational implant stability. 2. Varus-valgus-torque of ±3,5Nm to determine the bending behavior of the stem. A high precision optical 3D measurement system allowed simultaneous measuring of spatial micromotions of implant and bone. Based on these micromotions, relative motions at the implant-bone-interface and implant flexibility could be calculated.

Introduction

Kinematically or anatomically aligned total knee arthroplasty (TKA) has been reported to provide improved clinical outcomes by replicating patient's original joint line [1][2].

It has been known that tibial (joint line) varus varies among patients, and the tibial varus would increase over progression of arthritis and bone remodeling. For those patients with significant deformity, the current tibial varus may significantly differ from its pre-diseased state.

In this exploratory study, geometry and alignment of the tibial growth plate were measured with respect to tibial anatomical landmarks in order to better understand modes of tibial deformity and seek possible application in reconstructing pre-diseased joint alignment.

Methods

CT scans of sixteen healthy Japanese knees (M6:F10, Age 31.9±13.9 years) were studied. Three-dimensional reconstruction models were created using Mimics 17 (Materialise, Leuven, Belgium). First, a mid-sagittal tibial reference plane, for comparing the varus/valgus orientation of the tibial plateau to that of the growth plate, was defined by the medial margin of the tibial tuberosity, origin of the PCL and center of the foot joint. The tibial plateau (or joint line plane) was determined from three points; dwell point of femur (aligned in extension) on lateral tibial articular surface, and two points at anterior and posterior rim of medial tibial articular surface sampled in the sagittal view and coinciding with dwell point of femur on medial tibia.

Then, a three-dimensional model of the tibial growth plate was extracted using the Livewire function and mask editing tools in Mimics. To determine 3D orientation of the growth plate (GP), the vertical mass moment of inertia axis was calculated for the 3D model. The inertia axes were also determined for medial and lateral half of the GP (Figure 1).

Introduction / Purpose

Many factors can influence postoperative knee flexion angle after total knee arthroplasty (TKA), and range of flexion is one of the most important clinical outcomes. Although many studies have reported that postoperative knee flexion is influenced by preoperative clinical conditions, the factors which affect postoperative knee flexion angle have not been fully elucidated. As appropriate soft-tissue balancing as well as accurate bony cuts and implantation has traditionally been the focus of TKA success, in this study, we tried to investigate the influence of intraoperative soft-tissue balance on postoperative knee flexion angle after cruciate-retaining (CR) TKA using a navigation system and offset-type tensor.

Methods

We retrospectively analyzed 55 patients (43 women, 12 men) with osteoarthritis who underwent TKA using the same mobile-bearing CR-type implant (e.motion; B. Braun Aesculap, Germany). The mean age at the time of surgery was 74.2 (SD 7.3) years. The exclusion criteria for this study included valgus deformity, severe bony defect requiring bone graft or augmentation, revision TKA, active knee joint infection, and bilateral TKA. Intraoperative soft-tissue balance parameters such as varus ligament balance and joint component gap were measured in the navigation system (Orthopilot 4.2; B. Braun Aesculap) while applying 40-lb joint distraction force at 0°, 10°, 30°, 60°, 90°, and 120° of knee flexion using an offset-type tensor with the patella reduced. Varus ligament balance was defined as the angle (degree, positive value in varus imbalance) between the seesaw and platform plates of the tensor that was obtained from the values displayed by the navigation system. To determine clinical outcome, we measured knee flexion angle using a goniometer with the patient in the supine position before and 2 years after surgery. Correlations between the soft-tissue parameters and postoperative knee flexion angle were analyzed using simple linear regression models. Pre- and postoperative knee flexion angle were also analyzed in the same manner.

Purpose

Proximal femoral osteotomy is an attractive joint preservation procedure for osteonecrosis of the femoral head. The purpose of this study was to investigate the cause of failure of proximal femoral osteotomy in patients with osteonecrosis of the femoral head.

Patients and Methods

Between 2008 and 2014, proximal femoral osteotomy was performed by one surgeon in 13 symptomatic hips. Ten trans-trochanteric rotational osteotomies (anterior: 7, posterior: 3) and 3 intertrochanteric curved varus osteotomy were performed. Of the patients, 9 were male and 1 was female, with a mean age at surgery of 36.9 years (range, 25–55 years). The mean postoperative follow-up period was 38 months (range, 12–72 months). Three patients (4 hips) had steroid-induced osteonecrosis, and 7 (9 hips) had alcohol-associated osteonecrosis. At 6 postoperative weeks, partial weight bearing was permitted with the assistance of 2 crutches. At more than 6 postoperative months, full weight bearing was permitted. Patients who had the potential to achieve acetabular coverage of more than one-third of the intact articular surface on preoperative hip radiography, computed tomography, and magnetic resonance imaging were considered suitable for this operation. A clinical evaluation using the Japanese Orthopaedic Association (JOA) scoring system and a radiologic evaluation were performed. Clinical failure was defined as conversion to total hip arthroplasty (THA) or progression to head collapse and osteoarthritis. The 13 hips were divided into two groups, namely the failure and success groups.

Background

Residual stress remains in bone tissues after press-fit-fixation of a joint prosthesis, recently employed for joint arthroplasty. The response of bone tissues to the residual stress is, however, unknown because it is not physiological. This unnatural stimulus may have adverse effects on bone tissues, including causing thigh pain or bone resorption. In the present study, we designed an experimental method to apply a stationary load from inside an animal femur using a loop spring of titanium alloy with super elasticity. The femoral response was assessed based on the migration of the wire into bone twelve weeks after implantation. As the results, wire migration was noted in 10 of 11 cases.

Methods

We developed a method using a loop spring made of super elastic titanium alloy, which can maintain sufficient stress in a rat femur for a prolonged period. This titanium alloy, which contains 43.94% titanium and 56.06% nickel, was supplied as a wire (WDL1, Actment Co., Ltd., Kasukabe, Japan). In the present study, an experimental method was designed to apply a stationary load from inside a rat femur by inserting a loop spring made of super elastic wire.

Introduction

Short stems have been developed for some years for preservation of femoral bone stock and achieve physiological proximal loading. Shortening stem length is a merit for bone stock preservation. However, it might lead to reduction of primary stability. We investigated relationship between stem length and primary stability by patient specific finite element analysis (FEA).

Materials and Methods

Thirty-one hips in 31 patients were performed total hip arthroplasty with standard length tapered wedge-shaped (TW) cementless stem (CTi-II: Corin, Cirencester, UK). There were 6 males and 25 females. The average age at operation was 69 years old. The average body mass index was 23.9 kg/m2. Primary diagnoses were secondary osteoarthritis due to developmental dysplasia of the hip in 29 hips. Femoral canal shapes were normal in 21, stovepipe in 6 and champagne-flute in 4 hips. Bone qualities were type A in 6, B in 19 and C in 6 hips.

The patients underwent computed tomography (CT) preoperatively and postoperatively. We constructed preoperative three dimensional (3D) femur surface models from preoperative CT data with individual bone mineral density (BMD) mapping. The postoperative 3D femur and rough stem surface models were obtained from postoperative CT data. The coordinates of the postoperative femur were transformed to fit the preoperative femur model. A precise stem model constructed using computer-assisted design data was matched to the transformed rough stem model using the iterative closest point algorithm. We obtained a patient-specific model with the proximal bone geometry, allocation of BMD and stem alignment. We estimated the average of axial and rotational micromotion (MM) at stem-bone interface and the ratio of area (MM � 40 micrometers) on the porous surface in order to analyze primary stability of TW stem with several lengths (standard (100 %), 75 %, 50 %, 40 % and 30 % length).

Introduction

Three-dimensional (3D) printing is a precise method of reproducing complex structures. Orthopaedic surgeons may utilize 3D imaging to better plan procedures, design implants, and communicate with other providers and patients. However, one of the limitations of 3D printed models has been the high cost associated with third-party creation of such tools. With the recent increases in the use of 3D printing many publically available software programs have been developed, which allow for inexpensive office-based production of models. We present a simple, inexpensive technique which can be used by surgeons for the rapid fabrication of 3D models in-office.

Technique

CT scan and MRI's are stored in DICOM type format which must be transformed into a 3D image. This can be achieved using publically available programs (for example, 3D slicer (http://www.slicer.org/)). These images can be manipulated with this software, allowing for separation of individual bones. The files can then be exported from this program in an STL format. These models are then further enhanced and smoothed utilizing another open source software (Blender (https://www.blender.org)). The STL file can then be opened in a third open source program (for example, Meshlab http://meshlab.sourceforge.net/) which can analyze the mesh for extra vertices, voids, and discontinuities. At this point the STL file is ready for 3D printing. The file can be loaded onto the slicer software for calculation of a tool path and printing.

Introduction

The large diameter mobile polyethylene liner of the dual mobility implant provides increased resistance to hip dislocation. However, a problem specific to the dual mobility system is intra-prosthetic dislocation (IPD), secondary to loss of the retentive rim, causing the inner head to dissociate from the polyethylene liner. We hypothesized that impingement of the polyethylene liner with the surrounding soft-tissue inhibits liner motion, thereby facilitating load transfer from the femoral neck to the liner and leading to loss of retentive rim over time. This mechanism of soft-tissue impingement with the liner was evaluated via cadaver experiments, and retrievals were used to assess polyethylene rim damage.

Methods

Total hip arthroplasty was performed on 10 cadaver hips using 3D printed dual mobility components. A metal wire was sutured to the posterior surface (underside) of the iliopsoas, and metal wires were embedded into grooves on the outer surface of the liner and inner head to identify these structures under fluoroscopy. Tension was applied to the iliopsoas to move the femur from maximum hyperextension to 90° of flexion for the purpose of visualizing the iliopsoas and capsule interaction with the mobile liner. The interaction of the mobile liner with the iliopsoas was studied using fluoroscopy and direct visual observation. Fifteen retrieved dual mobility liners were assessed for rim edge and rim chamfer damage. Rim edge damage was defined as any evidence of contact, and rim chamfer damage was classified into six categories: impact ribs on the chamfer surface, loss of machining marks, scratching or pitting, rim deformation causing a raised lip, a rounded rim edge, or embedded metal debris.

Purpose

The aim of the current study was to evaluate the clinical and radiographic results of primary total hip arthroplasty (THA) performed with the Alloclassic Variall system (a modified version of the Alloclassic Zweymüller system) and to compare them with those in the literature for the original system.

Methods

Between January 2001 and December 2002, 273 consecutive primary THAs were performed in 259 patients at a single centre with the study system, using ceramic-on-ceramic (81.7%) or ceramic-on-highly-crosslinked-polyethylene (18.3%) articulations.

Introduction

Arthroplasties of hip and knee are associated with blood loss, which may lead to adverse patient outcome. Jehovah's Witnesses do not accept blood transfusion. Performing arthroplasties in Witness patients without transfusion has been a matter of concern. We developed a protocol, which avoids transfusion in arthroplasties of Witness patients, and evaluated the feasibility and safety of the protocol.

Materials and Methods

Our protocol consisted of subcutaneous administration of 4000 U recombinant erythropoietin and 100 mg of intravenous iron supplements when patient's hemoglobin level was less than 10 g/dL in preoperative evaluation. During the operation, cell saver, and plasma expander were used. Postoperatively, recombinant erythropoietin was administered three times a week and iron supplements were administered daily until the hemoglobin level reached 10 g/dL. We evaluated the feasibility of our protocol, perioperative complications and hematologic changes.

Introduction

The Primoris® femoral stem was designed to preserve bone and maintain normal stress to the proximal femur, thereby minimizing stress-shielding. The implant is anchored in the femoral neck and metaphysis without diaphysial involvement and differs from other neck prothesis by: a) Elliptical shape to fit the inner neck dimensions. b) On top of Ti– porous-coating electrochemically deposited hydroxy apatite (Bonemaster®) c) The surgical technique aims to enhance initial implant stability by compaction of neck and metaphyseal cancellous bone.

Objectives

As part of stepwise introduction to monitor bone remodeling, RSA data and clinical results.

INTRODUCTION

Ultra-High Molecular Weight Polyethylene (UHMWPE) wear debris is thought to be a main factor in the development of osteolysis (1). However, the method for the evaluation of the biological response to UHMWPE particles has not yet been standardized.

In this study, four different types of UHMWPE particles were generated using a mechanized pulverizing method and the biological responses of macrophages to the particles were investigated using an inverted cell culturing process (2).

MATERIALS & METHODS

Virgin samples were manufactured via Direct Compression Molding (DCM) technique from UHMWPE GUR1050 resin powder (Ticona, USA). For vitamin E (VE)-blended sample, the resin was mixed with VE at 0.3 wt% and the mixture was then molded using DCM. The crosslinked virgin samples were made by gamma ray irradiation to UHMWPE GUR1020 resin sheet (Meditech, USA) with doses of 95kGy ±10% and annealed. The VE-blended crosslinked samples were made by electron beam irradiation to VE-blended samples with doses of 300kGy and annealed. The material conditions were summarized in Figure 1. To pulverize the samples, the Multi-Beads Shocker (Yasui Kikai, Japan) was used.

After pulverization, samples were dispersed in an ethanol solution and sequentially filtered through polycarbonate filters. Over 100 sections of the filter were selected randomly and images of the particles were analyzed using scanning electron microscope (SEM).

To analyze the macrophage biological response, an inverted cell culturing process was used (2). The mouse macrophage-like cells were seeded at densities of 4×105cells per well in a 96-well culture plate and incubated for 1h. UHMWPE particles suspended in the culture medium were then added to each well in the appropriate amount. After that, fresh medium was added to fill the wells, and a sealing film was used to cover the culture plate. The culture plate was then inverted to cause the UHMWPE particles interact with the adhered macrophages. The inverted culture plate was incubated for 8h. The amount of TNF-α was measured by enzyme-linked immunosorbent assay (ELISA).

Introduction

Restoration of knee function after total knee arthroplasty (TKA) often entails a balance between normal kinematics and normal knee stability, especially in performing demanding physical activities. The ultra-congruent (UC) knee design prioritizes stability over kinematics through close conformity between the femoral component and the tibial insert in extension. This configuration is intended to provide AP stability in the absence of the posterior cruciate ligament during activities that would otherwise cause anterior femoral subluxation. In this study we examine the kinematics of an ultra-congruent knee design in comparison with the intact knee and with conventional articulations used in PCL-retaining (CR) and PCL-substituting (PS) TKR designs.

Materials and Methods

The 3D tibio-femoral kinematics of 6 fresh frozen cadaveric human knees were tested during loaded simulation of squatting in a computer-controlled knee testing rig. Muscle forces were simulated by loading rectus femoris and vastus intermedius (150N), vastus lateralis (100N), vastus medialis (75N), and the hamstring muscles (60N) (total: 385N). Testing was performed on the intact knee, and after implanting a standard design of total knee prosthesis with the posterior cruciate ligament intact (CR-TKA), resected (PCL-substituting insert; PS-TKA), and a UC insert (UC-TKA group). The 3D positions of the tibia and femur were tracked with a high resolution 12 camera motion analysis system (Motion Analysis Inc.) and used to position 3D CT reconstructions of each bone. The translation and rotation of the femur with respect to the tibia were calculated by projecting the femoral transcondylar axis onto a plane normal to the longitudinal anatomical axis of the tibia coincident with the transverse axis of the tibial plateau.

Introduction

Angular mismatch between the head and trunnion is recognized as a contributing factor to mechanically-assisted corrosion of modular hip prostheses. Although manufacturing standards have been adopted to define acceptable tolerances for taper angles of mating components, the relationship between the head and trunnion taper angles (positive or negative) differs between manufacturers. In this study, we investigated the effect of positive and negative angular mismatch on the interface mechanics of a standard design of taper junction using finite element analysis (FEA).

Methods

Computer simulations were executed using an FE model which had been previously verified through direct comparison with experimental studies. The neck and trunnion of a Ti6Al4V femoral component (taper size: 12/14mm) were modelled using a stable hexahedral mesh (33,648 elements), while the femoral head (CoCrMo, size: 32mm) was modelled using a tetrahedral mesh (51,182 elements). Assembly of the head on the trunnion was simulated through the application of a load of 4000N along the trunnion axis. This was followed by the application of a gait load of 1638N (2.34×700N BW) at an angle of 30o to the trunnion axis. A friction-based sliding interface (mu=0.12) was simulated at the trunnion-head junction. A linear static solution was set up using Siemens NX Nastran. In addition to a perfect match, 7 positive and negative mismatch angles were simulated ranging from −0.100 to 0.100 degrees. Head taper interface motion, contact pressure and internal stresses (von Mises) were calculated for each mating condition.

Summary

There is tremendous variability amongst surgeons' ability to reference anatomic landmarks. This may suggest the necessity of other objective methods in determining femoral alignment and rotation.

Introduction

Despite the durability of total knee arthroplasty, there is much room for improvement with regards to functional outcome and patient satisfaction. One important factor contributing to poor outcomes after TKA is malrotation of the femoral component. It has been postulated that this is due to failure of surgeons to correctly reference bony landmarks, principally the femoral epicondyles, however, this is unproven. The purpose of this study was to evaluate the accuracy of joint surgeons and trainees in identifying anatomic landmarks for positioning the femoral component and to determine the effect of prior training and experience.

Introduction

Relative motion at the modular head-neck junction of hip prostheses can lead to severe surface damage through mechanically-assisted corrosion. One factor affecting the mechanical performance of modular junctions is the frictional resistance of the mating surfaces to relative motion. Low friction increasing forces normal to the head-neck interface, leading to a lower threshold for slipping during weight-bearing. Conversely, a high friction coefficient is expected to limit interface stresses but may also allow uncoupling of the interface in service. This study was performed to examine this trade-off using finite element models of the modular head-neck junction

Methods

A finite element model (FEM) of the trunnion/ head assembly of a total hip prosthesis was initially created and experimentally validated. CAD models of a stem trunnion (taper size: 12/14mm) and a prosthetic femoral head (diameter: 28mm) were discretized into elements for finite element analysis (FEA). The trunnion (Ti6Al4V) was modelled with a hexahedral mesh (33,648 elements) and the femoral head (CoCrMo) with a tetrahedral mesh (51,182 elements). A friction-based sliding contact interface was defined between the mating surfaces. The model was loaded in 2 stages: (i) an assembly load of 4000N applied along the trunnion axis, and (ii) 500N applied along the trunnion axis in combination with a torque of 10Nm. A linear static solution was set up using Siemens NX-Nastran solver. Multiple simulations were executed by modulating the frictional coefficient at the taper-bore interface from 0.05 to 0.15 in increments of 0.01, the coefficient of 0.1 serving as the control case (Swaminathan and Gilbert, 2012).

Introduction

The success of knee replacement surgery depends, in part, on restoration of the correct alignment of the leg with respect to the load-bearing vector passing from the hip to the ankle (the mechanical axis). Conventional thinking is that the correct angle of resection of the distal femur (Valgus Cut Angle, VCA) depends on femoral length or femoral offset, though femoral bowing, in addition to length and medial offset, may also have a significant influence on the VCA. We hypothesized that femoral bowing has a strong effect on the VCA necessary to restore physiologic alignment after arthroplasty or osteotomy.

Methods

A total of 102 long-leg radiographs were obtained from patients scheduled for primary total knee arthroplasty. The patients on average were 41% male 59% female, 67.9 ± 11.1 years, 67.0 ± 4.7 in, 192 ± 43 lbs, and had a BMI of 29.7 ± 4.8. All radiographs were prepared with the feet placed in identical rotation and the patellae pointing forward, and were excluded if there was evidence of malrotation, as defined by (i) a difference in the medial head offsets of the right and left femur of >3mm, (ii) a difference in the width of the tibiofibular syndesmoses, or (iii) a difference in the rotation of one foot compared to the other.

The following anatomic variables were measured on each radiograph: (i) the neck shaft angle (NSA) of the femur, (ii) the length of the femur, (iii) the length of the femoral shaft, (iv) the medial head offset, (v) the medial-lateral bow of the distal femur, (vi) the hip- knee axis angle, (vii) the mechanical axis deviation of the extremity at the knee, (viii) the medio-lateral bow of the tibia, and (ix) the valgus cut angle required to restore the mechanical axis to the center of the knee during surgery (VCA). Bivariate plots were constructed using the measurements thought to influence the VCA: femoral bowing, femoral offset, and length of femur. Multivariate regression was then used to find the variable that had the strongest effect on the VCA.

Introduction

In clinical routine surgeons depend largely on 2D x-ray radiographs and their experience to plan and evaluate surgical interventions around the knee joint. Numerous studies have shown that pure 2D x-ray radiography based measurements are not accurate due to the error in determining accurate radiography magnification and the projection characteristics of 2D radiographs. Using 2D x-ray radiographs to plan 3D knee joint surgery may lead to component misalignment in Total Knee Arthroplasty (TKA) or to over- or under-correction of the mechanical axis in Lower Extremity Osteotomy (LEO).

Recently we developed a personalized X-ray reconstruction-based planning and post-operative treatment evaluation system called “iLeg” for TKA or LEO. Based on a patented X-ray image calibration cage and a unique 2D–3D reconstruction technique, iLeg can generate accurate patient-specific 3D models of a complete lower extremity from two standing X-rays for true 3D planning and evaluation of surgical interventions at the knee joint. The goal of this study is to validate the accuracy of this newly developed system using digitally reconstructed radiographs (DRRs) generated from CT data of cadavers.

Methods

CT data of 12 cadavers (24 legs) were used in the study. For each leg, two DRRs, one from the antero-posterior (AP) direction and the other from the later-medial (LM) direction, were generated following clinical requirements and used as the input to the iLeg software. The 2D–3D reconstruction was then done by non-rigidly matching statistical shape models (SSMs) of both femur and tibia to the DRRs (seee Fig. 1).

In order to evaluate the 2D–3D reconstruction accuracy, we conducted a semi-automatic segmentation of all CT data using the commercial software Amira (FEI Corporate, Oregon, USA). The reconstructed surface models of each leg were then compared with the surface models segmented from the associated CT data. Since the DRRs were generated from the associated CT data, the surface models were reconstructed in the local coordinate system of the CT data. Thus, we can directly compare the reconstructed surface models with the surface models segmented from the associated CT data, which we took as the ground truth. Again, we used the software Amira to compute distances from each vertex on the reconstructed surface models to the associated ground truth models.

Introduction and Aims

In order to improve the longevity and design of an implant, a wide range of pre-clinical testing conditions should be considered including variations in surgical delivery, and patients' anatomy and biomechanics. The aim of this research study was to determine the effect of the acetabular cup inclination angle with different levels of joint centre mismatch on the magnitude of dynamic microseparation, occurrence and severity of edge loading and the resultant wear rates in a hip joint simulator.

Methods

The six-station Leeds Mark II Anatomical Physiological Hip Joint Simulator and 36mm diameter ceramic-on-ceramic bearings (BIOLOX® delta) were used in this study. A standard gait cycle, with a twin-peak loading (2.5kN peak load and approximately 70N swing phase load), extension/flexion 15°/+30° and internal/external ±10° rotations, was applied. Translational mismatch in the medial-lateral axis between the centres of rotation of the head and the cup were considered. In this study, mismatches of 2, 3 and 4 (mm) were applied. Two acetabular cup inclination angles were investigated; equivalent to 45° and 65° in-vivo. These resulted in a total of six conditions [Figure 1] with n=6 for each condition. Three million cycles were completed under each condition. The lubricant used was 25% (v/v) new-born calf serum supplemented with 0.03% (w/v) sodium azide to retard bacterial growth. The wear of the ceramic bearings were determined using a microbalance (XP205, Mettler Toledo, UK) and a coordinate measuring machine (Legex 322, Mitutoyo, UK). The stripe wear was analysed using RedLux software. The dynamic microseparation displacement was measured using a linear variable differential transformer. Mean wear rates and 95% confidence limits were determined and statistical analysis (one way ANOVA) completed with significance taken at p<0.05. Results Increasing the medial-lateral joint centre mismatch from 2 to 3 to 4mm resulted in an increased dynamic microseparation [Figure 2]. A similar trend was observed for the wear. A higher level of medial-lateral mismatch increased the wear rate under both 45° and 65° cup inclination angle conditions [Figure 3]. The mean wear rates obtained under 65° were significantly higher compared to those obtained under the 45° cup inclination angle conditions for a given medial-lateral mismatch in the joint centre (p=0.02 for 2mm mismatch, p=0.02 for 3 mm mismatch, and p<0.01 for 4mm mismatch).

Introduction

Quadriceps performance following total knee arthroplasty (TKA) is a critical factor in patient satisfaction that can be significantly affected by implant design (Greene, 2008). The objective of this study was to compare quadriceps efficiency (QE) following TKA with a medial-pivot system (EVOLUTION®, MicroPort Orthopedics Inc., Arlington, TN, USA) to non-implanted control measurements.

Methods

Five cadaveric leg specimens with no prior surgeries, deformities, or disease were obtained. Each was placed in a custom closed chain device and loaded to simulate a heel-up squat from full-extension to deep flexion (approximately 115°) and back to full extension. Quadriceps force (FQ) and ground reaction force (FZ) were measured, and the ratio of the two was calculated as the quadriceps load factor (QLF). QFLs are inversely related to QE, with higher QFLs representing reduced efficiency. Each specimen was then implanted with a medial-pivot implant by a board certified orthopedic surgeon and force measurements were repeated. Mean pre- (represents control values) and post-implantation QFLs were compared to determine any differences in QE throughout the range of motion.

Introduction

The incidence of dislocation after total hip arthroplasty (THA) was reported to be 0.5 to 10% in primary THA and 10 to 25 % in revision THA. The main causes of instability after THA were reported to be implant malalignment and inappropriate soft tissue tension. However, there was no study about quantitative data of soft tissue tension of unstable THA. The purpose of this study is to clarify the features of soft tissue tension of unstable THA in comparison to stable THA.

Methods

The subjects were 15 patients with 15 THAs who had developed recurrent dislocation after primary THA. Thirty four patients with 37 THAs who developed no dislocation for one year after surgery were recruited as a stable THA group. In both group, all THAs were performed through posterolateral approach. In order to assess the soft tissue tension of THA, we recorded antero-posterior radiographs of the hips while applying distal traction to the leg with traction forces of 20?, 30%, 40% of body weight (BW). The distance of separation of the head and the cup after traction was measured under correction of magnification. Nine of 15 THAs in the unstable THA group and 32 of 37 THAs in the stable THA group were unilateral involvement. In the hips with unilateral involvement, the femoral offset difference between the healthy hip and the reconstructed hip were evaluated. Statistical analysis was performed with χ2 testand Mann-Whitney U test, and statistical significance was set at P<0.05.

Introduction

The aim of the present study was to evaluate the discrepancies of rotational profiles of whole limb between operated and non-operated limb following unilateral total knee arthroplasty.

Materials and Methods

We conducted an analysis the CT data from 32 patients undergoing primary unilateral total knee arthroplasty using measured resection technique, which femoral component was always implanted with external rotation to posterocondylar axis from July 2009 to April 2013. Using these CT scan, rotational profiles of total limb such as femoral torsion angle (femoral neck anteversion angle; FTA), tibial torsion angle (TTA), knee joint rotation angle (KJRA) and total limb rotation (TLR) were measured.

Purpose

The positon of short stem is affected by the native anatomy of femoral neck and also by fixation mechanism dependent on design. As a consequence, it has been speculated that restoration of hip geometry might be limited in total hip arthroplasty (THA) using short stem. Therefore, the present study assessed the predictability of restoration of hip geometry using two different CCD-angled short stem engaging the lateral cortex

Materials and Methods

The 60 patients included 15 females and 45 males. The average age was 48.0 years with average BMI 24.2. Biomechanical parameters of hip geometry were analysed on postoperative calibrated radiographs in 30 consecutive primary unilateral THAs using short stem (Metha®, B. Braun Aesculap, Tuttlingen, Germany) with 120° CCD angle (group I) and 30 match controlled cases with 135° CCD angle (group II) and compared to those of the contralateral hip without deformity. The matching process was done before collecting the radiographic measurements by two blinded observer and was for sex, age ± 5 years, and BMI ± 7 units in that order.

Background

Total knee arthroplasty has been performed even for severe valgus knee. All ligaments around knee must be balanced to obtain good clinical results. Especially medial collateral ligament plays a role as a stabilizer. For severe valgus knee, however, deep medial collateral ligament (dMCL) located closely to the articulating tibial surface [Fig. 1] can be damaged by bone resection in standard tibial osteotomy which may leads to progress valgus deformity.

Purpose

There are no report of dMCL preserved total knee arthroplasty for sever valgus knee. Thus it was evaluated the clinical outcomes of total knee arthroplasty for severe valgus knees using dMCL preservation technique.

Introduction

Bulk bone grafting is commonly used in total hip arthroplasty (THA) for developmental dysplasia. However, it is a technically demanding surgery with several critical issues, including graft resorption, graft collapse, and cup loosening. The purpose of this study is to describe our new bone grafting technique and review the radiographic and clinical results.

Patients and Methods

We retrospectively reviewed 105 hips in 89 patients who had undergone covered bone grafting (CBG) in total hip arthroplasty for developmental dysplasia. We excluded patients who had any previous surgeries or underwent THA with a femoral shortening osteotomy. According to the Crowe classification, 6 hips were classified as group I, 39 as group II, 40 as group III, and 20 as group IV. Follow-up was at a mean of 4.1 (1 ∼ 6.9) years. The surgery was performed using the direct anterior approach. The acetabulum was reamed as close to the original acetabulum as possible. The pressfit cementless cup was impacted into the original acetabulum. After pressfit fixation of the cup was achieved, several screws were used to reinforce the fixation. Indicating factor for using CBG was a large defect where the acetabular roof angle was more than 45 degrees and the uncovered cup was more than 2 cm (Fig.1). The superior defect of the acetabulum was packed with a sufficient amount of morselized bone using bone dust from the acetabular reamers. Then, the grafted morselized bone was covered with a bone plate from the femoral head. The bone plate was fixed with one screw to compact the morselized bone graft. The patient was allowed to walk bearing full weight immediately after surgery. We measured the height of the hip center from the teardrop line and the pelvic height on anteroposterior roentgenograms of the pelvis and calculated the ratio of the hip center to the pelvic height. We defined the anatomical hip center as the height of the center less than 15 % of the pelvic height, which was nearly equal to 30 mm, because the mean pelvic height was 210 mm.

Introduction

Cobalt-Chromium-Molybdenum (CoCr) and Titanium-Aluminium-Vanadium (Ti) alloys are the most commonly used alloys used for Total Hip Replacement due to their excellent biocompatibility and mechanical properties. However, both are susceptible to fretting corrosion In-vivo. The objective of this study was to understand the damage mechanism of both combinations through a sub-surface damage assessment of the alloys at various fretting amplitudes using the Transmission Electron Microscopy (TEM – CM200 FEGTEM). The TEM was used to attain a cross sectional view of the alloys in orderto see the effect of high shear stress on the grain structure.

Methods

The two combinations were fretted at a maximum contact pressure of 1 GPa in a Ball – on – Plate configuration for displacement amplitudes of 10μm, 25μm, 50μm and 150μm. The contact was lubricated with 25% v/v Foetal Bovine Serum (FBS), diluted with Phosphate Buffered Saline (PBS). The material loss through wear and corrosion from the fretting contact were quantified using the Visual Scanning Interferometry (VSI). The TEM samples were obtained using the Focused Ion Beam (FIB – FEA Nova 200 Nanolab). Samples were obtained from regions of high stress (shaded in red) [Fig. 1] for both CoCr and Ti flat of the CoCr–CoCr and CoCr–Ti couples respectively.

Introduction

The purpose of this study was to introduce our perioperative prophylaxis method for infection and clarify surgical site infection rate in our patients performed total hip arthroplasty (THA).

Method

Two hundred and eighty four THA (including revision 18 cases) performed by single surgeon between Oct. 2007 and Jan. 2013 were evaluated. The mean age of patients was 65.7 years old. The male to female ratio was 46 to 238. BMI was 23.6. Ninety patients (32%) were compromised host suffering from diabetes mellitus, rheumatoid arthritis, autoimmune disease, history of malignant tumor, hemodialysis or skin disease at surgical site respectively. At preoperative period, we checked decayed tooth, alveolar pyorrhea, hemorrhoids, and leg skin condition. In addition, we examined culture of nasal cavity. At the day of surgery, patient took a shower just before entering surgical room. All of THA was performed in clean room NASA class 100. Surgeons and assistant nurse put on nonwoven fabric gown, space suit and double rubber gloves. We wiped surgical site leg by gauze impregnated by 0.5% chlorhexidine alchohol to eliminate skin bacteria twice just before surgeons scrubbing hands. Surgical site was covered by povidone iodine containing drape. Surgeons or nurse changed gloves when glove was broken at each time. We cleaned surgical field by pulse washer whenever necessary. We did not use drain except for 5 revision THAs. Regarding to prophylactic antibiotics usage, we administered cefcapene pivoxil orally the day before surgery. Drip infusion antibiotics (PIPC: until Oct. 2008, CEZ: after Oct. 2008) was administered at the period of 30 min. before surgery and 4 hours after surgery in case of prolonged surgical time (4 hours >). Skin closure was performed by staple and covered by gauze until May 2010. After that, we used surgical tape and transparent water proof sheet. After finishing surgery, antibiotic was administered 8 hours interval at surgery day and 12 hours interval for additional two days. In case multi-drug resistant bacteria (MRSA, MRSE) was positive in nasal culture, we applied mupirocin ointment to nasal cavity for 3 days before surgery and administered vancomycin (from Aug. 2011) or linezolid (from 2012) for prophylactic antibiotics in perioperative period.

Introduction

Highly cross-linked ultrahigh molecular weight polyethylene (UHMWPE) is the most common bearing surface used in total joint arthroplasty due to its excellent wear resistance. While radiation cross-linking is currently used, cross-linking using a cross-linking agent such as a peroxide can also be effective with improved oxidative stability, which can be achived by an antioxidant such as vitamin E. The peroxide cross-linking behavior of UHMWPE in the presence of vitamin E was unknown. We investigated the cross-linking behavior and the clinically relevant mechanical and wear properties of peroxide cross-linked, vitamin E-blended UHMWPE.

Materials and Methods

Medical grade UHMWPE (GUR1050) was blended with vitamin E and the peroxide (2,5-Dimethyl-2,5-di(t-butylperoxy)hexyne-3 or P130) before compression molding. Various vitamin E (0.1, 0.2, 0.3, 0.5, 0.6, 0.8 and 1.0 wt%) and peroxide concentrations (0.5, 1 and 1.5 wt%) were studied. The cross-link density was calculated as previously described (Oral 2010). The wear rate was determined using a custom-designed pin-on-disc wear tester against CoCr polished discs at 2 Hz and a rectangular path of 5 × 10 mm in undiluted bovine serum (Bragdon 2001). Tensile mechanical properties were determined using Type V dogbones according to ASTM D638. Oxidative stability was determined using oxidation induction testing (Braithwaite 2010). Double-notching and IZOD impact testing was performed according to ASTM D256. Samples prepared with vitamin E concentrations of 0.3 wt% and above and P130 concentrations of 0.5 and 1 wt% were also terminally gamma sterilized. Controls were 150-kGy irradiated vitamin E blends of UHMWPE.

Introduction

Inradiation cross-linked and melted ultrahigh molecular weight polyethylene (UHMWPE) total joint implants, the oxidation potential is afforded to the material by by post-irradiation melting. The resulting cross-linked UHMWPE does not contain detectable free radicals at the time of implantation and was expected to be resistant against oxidation for the lifetime of the implants. Recently, analysis of long-term retrievals revealed detectable oxidation in irradiated and melted UHMWPEs, suggesting the presence of oxidation mechanisms initiated by mechanisms other than those involving the free radicals at the time of implantation. However, the effect of oxidation on these materials was not well studied. We determined the effects of in vitro oxidation on the wear and mechanical properties of irradiated and melted UHMWPEs.

Materials and Methods

Medical grade slab compression molded UHMWPE (GUR1050) was irradiated using 10, 50, 75, 100, 120 or 150 kGy. The irradiated and melted UHMWPEs were accelerated aged at 70°C for 2, 3, 4, 6 and 8 weeks at 5 atm of oxygen.

Oxidation profiles were determined by first microtoming 150 μm cross sections; these were then extracted by boiling hexane for 16 hours and vacuum dried for 24 hours. They were then analyzed on an infrared microscope as a function of depth away from the surface. An oxidation index was calculated per ASTM 2102 as the ratio of the area under the carbonyl peak at 1740 cm-1 to the area under the crystalline polyethylene 1895 cm-1 peak. The cross-link density was calculated as previously described (Oral 2010). The wear rate was determined using a custom-designed pin-on-disc wear tester against CoCr polished discs at 2 Hz and a rectangular path of 5 × 10 mm in undiluted bovine serum (Bragdon 2001). Tensile mechanical properties were determined using Type V dogbones according to ASTM D638.

Objective

The aim of this study was to evaluate the shape of patella relative to the femoral epicondylar axis and to find sex differences.

Materials and methods

Computed tomography (CT) images of 100 knees with tibiofemoral osteoarthritis in 100 patients were prospectively collected. All patients were diagnosed as varus-type osteoarthritis with no destructive patellar deformity.

Fifty patients were male and 50 female. The average male age was 70.8±14.6 (mean ± SD) years and the average female age was 73.3±6.7 years. Forty nine knees were right and 51 knees were left. The average height of males was 162.6±7.4 cm and that of females 149.6±5.7 cm. Males were significantly taller than females.

The CT scan was performed with 2mm-interval slices in the vertical plane to the long axis of femoral shaft. Every CT image was examined to determine the maximum distance between the medial and lateral femoral epicondyle (inter-epicondylar distance, IED) along the epicondylar axis. The maximum patellar width and thickness were also measured at the image which had these maximum distances, while patellar cartilage thickness in anteroposterior diameter was not measured in this study.

For evaluating the patellar size, each measured value was divided by IED and calculated each ratio. The ratio of patellar width to patellar thickness was also calculated. All parameters were compared between males and females.

Statistical software Statview ver.5.0 (SAS Institute Inc.) was used for all analyses with significance being set at the 5% level.

Background

Total knee arthroplasty (TKA) is the highly developed procedure for sever osteoarthritic knee, in which there are two major concepts; Cruciate Retaining design (CR) and Posterior Stabilized design (PS). The femoral roll back movement is enforced with the post-cam mechanism in the PS, however, this structure associates with the complications, i.e. wear and dislocation. The CR has been developed to obtain the knee stability with native posterior cruciate ligament (PCL) in TKA. However, the preservation of the PCL can limit knee exposure and increase the technical challenge of surgery. We hypothesized that the knee exposure was easily achieved after the PCL was released, however, the PCL was repaired and the posterior stability was re-established after the TKA with time if it was released subperiostealy.

Objective

The objective of this study was to evaluate the varying of the posterior stability after the PCL-released CR TKA.

Introduction

The dual mobility cup was introduced in the 1970s to allow extensive range of motion associated with great stability thanks to double articulation; the first between the head and polyethylene, the second between the polyethylene and the cup.

The original plan was to install a stainless-steel uncemented cup coated with a thin layer of alumina and a metal head of 22,2 mm with a polyethylene liner of first generation.

Long term follow-up case studies are cited in the literature showing excellent results in reducing dislocations; however wearing and aseptic loosening are noted.

The new dual-mobility cups, with reticular polyethylene and titanium and hydroxyapatite coating are proving as reliable as the older ones in terms of stability whilst they appear to be more durable.

Furthermore, cemented dual-mobility cups are available, these are the topic of this study. One of the most frequent complications in the major revisions of hip replacement is dislocation. This study summarises our experience gathered in the use of dual-mobility cups during revisions of complex cases (GIR III-IV femoral or acetabular).

Materials and Methods

Between July 2014 to March 2015, we have implanted 13 cemented cups with dual-mobility (Avantage® Biomet) each in different patients, who have undergone revision with severe ostheolysis (GIR III-IV femoral or acetabular). The mean age of patients was 71.5 years old (46 to 89).

Indications for revisions were: aseptic loosening in 7 patients (two at third surgery), recurrent dislocation in 3 patients, 1 septic loosening, 1 revision after spacer removal e 1 post-traumatic.

We used dual-mobility cup in revision surgery when implant stability could have been compromised due to difficult positioning of acetabular component in cases of walls defects or muscolar laxity. The patients have been evaluated clinically and radiographically.

INTRODUCTION

Ceramic hip components are known for their superior material properties and longevity. In comparison to other materials commonly used, ceramics have a very low friction coefficient and a high fracture load. However, even though in-vivo fractures of ceramic ball heads are a relatively rare occurrence compared to other reasons for revision, they are of concern to the surgeon using ceramic components. The goal of this work was to evaluate the most probable causes for fracture and to quantify the influence of the metal taper contamination and shell deformation, respectively.

METHODS

An experimental set-up imitating the in-vivo loading situation was used to analyze different scenarios that may lead to the fracture of the ball heads, such as dynamic loading, edge loading and the metal taper contamination.

58 ceramic ball heads made of pure alumina were loaded until fracture under various conditions. Parameters under investigation were the inclination of the insert, the loading velocity, and the contamination of the interface between taper and ball head.

Introduction

One of the major concerns in the use of modular hip prostheses is the structural failure of one or more components of the prosthesis, with total mechanical failure. In literature there are sporadic cases of breakage of the prosthetic neck in patients with high functional demand.

Material and methods

In our experience we have implanted a model of modular hip prostheses in 38 patients. In 17 of these patients it was implanted a neck made of titanium alloy, while in the remaining 21 was utilised a CrCo neck. In 5 of the 17 patients with neck titanium it has been a spontaneous rupture of the neck in a time ranging from 12 to 24 months. We proceeded with the replacement of the titanium neck with similar neck made of CrCo alloy in 5 patients with failed neck, and we decided to call the remaining 12 patients with titanium neck, offering them the revision of the system. All patients accepted the revision surgery.

Purpose

The purpose of this study was to demonstrate postoperative improvement and high satisfaction rates after a surgical approach that includes arthroscopic labral repair only, in patients with borderline dysplasia, without instability.

Methods

Between September 2009 and December 2011, patients less than 50 years old who underwent hip arthroscopy for symptomatic intra-articular hip disorders, with a lateral center-edge (CE) angle between 20 and 25, were included in this study. Patients with Tönnis grade 2 or greater, hip joint space narrowing, severe hip dysplasia, hip joint instability and Legg-Calve-Perthes disease were excluded. Patient-reported outcome scores, including the modified Harris Hip Score (mHHS), Western Ontario and McMaster Universities Arthritis index (WOMAC), and visual analog scale (VAS) for pain were obtained in all patients preoperatively and at 1, 2, and 3 years postoperatively.

Introduction

Most surgeons that have performed kinematically aligned TKA have noticed an overall better clinical outcome, better motion, better patient satisfaction, and a quicker recovery than their patients treated with mechanically aligned TKA.

Materials and Methods

We prospectively followed all 128 knees who underwent primary total knee arthroplasty. The Lysholm knee score and VAS scale was recorded initially and 12months after the surgery. Independent T-test was used for statistical analysis at probability level of 95%. SPSS for Windows (Version 12, Chicago, Illinois) was used.

Introduction

Modern ceramic-on-ceramic bearings have become attractive alternatives to conventional polyethylene due to their low wear and minimal particle production. However, ceramic-on-ceramic implants have been associated with ceramic fracture and squeaking. To address these issues, large ceramic heads with a titanium-alloy sleeve have been introduced although limited data are available on their clinical outcomes. The purpose of this study was to report the midterm results of primary total hip arthroplasty using a 32mm with a titanium-alloy sleeve.

Materials & Methods

We reviewed 245 patients who had 274 total hip arthroplasties with a 32 mm ceramic head with a titanium-alloy sleeve and had been followed for more than 5 years (average, 6.5 years; range, 5–9 years). The mean patient age at the time of surgery was 55.1 years (range, 16–82 years). All operations were performed at a single center. All of the ceramic implants were hot isostatic pressed, laser-marked, proof-tested third-generation alumina (Fig. 1). We determined the implant survival, Harris hip scores, incidence of ceramic fracture or noisy hips, and presence of osteolysis.

Introduction

Highly cross-linked polyethylene has been introduced to decrease osteolysis secondary to polyethylene wear debris generation, but there are few long-term data on revision total hip arthroplasty using highly cross-linked polyethylene liners. The purpose of this study was to report the long-term radiographic and clinical outcomes of a highly cross-linked polyethylene liner in revision total hip arthroplasty.

Materials & Methods

We analyzed 63 revision total hip arthoplasties that were performed in 63 patients using a highly cross-linked polyethylene liner between April 2000 and February 2005. Of these, nine died and four were lost to follow-up before the end of the 10-year evaluation. Thus, the final study cohort consisted of 50 patients (50 hips). There were 26 males and 24 females with a mean age at time of revision total hip arthoplasty of 53 years (range, 27–75 years). Mean duration of follow-up was 11 years (range, 10–14 years).

Introduction

As the proximal femoral bone is generally compromised in failed total hip arthroplasty, achievement of solid fixation with a new component can be technically demanding. Clinical studies have demonstrated good medium-term results after revision total hip arthroplasty using modular fluted and tapered distal fixation stems, but, to our knowledge, long-term outcomes have been rarely reported in the literature. The purpose of this study was to report the minimum ten-year results of revision total hip arthroplasty using a modular fluted and tapered distal fixation stem.

Materials & Methods

We analyzed 40 revision THAs performed in using a modular fluted and tapered distal fixation stem (Fig. 1) between December 1998 and February 2004. There were 11 men (12 hips) and 28 women (28 hips) with a mean age of 59 years (range, 38 to 79 years) at the time of revision THA. According to the Paprosky classification of femoral defects, 5 were Type II, 24 were Type IIIA, and 11 were Type IIIB. An extended trochanteric osteotomy was carried out in 21 (52%) of the 40 hips. Patients were followed for a mean of 11.7 years (range, 10 to 15 years).

Introduction

Patients with osteonecrosis of the femoral head are typically younger, more active, and often require high rates of revision following primary total hip arthroplasty. However, outcomes of revision hip arthroplasty in this patient population have been rarely reported in the literature. The purpose of this study was to report the intermediate-term clinical and radiographic outcomes of revision hip arthroplasty in patients with osteonecrosis of the femoral head.

Materials & Methods

Between November 1994 and December 2009, 187 revision hip arthoplasty were performed in 137 patients who had a diagnosis of osteonecrosis of the femoral head. Exclusion criteria included infection, recurrent instability, isolated polyethylene liner exchange, and inadequate follow-up (less than 3 years). The final study cohort of this retrospective review consisted of 72 patients (75 hips) with a mean age of 53.3 years (range, 34 to 76). Components used for the acetabular revision included a cementless porous-coated cup in 58 hips and an acetabular cage in 2 hips. Components used for the femoral revision included a fully grit-blasted tapered stem in 30 hips and a proximally porous-coated modular stem in 9 hips. The mean duration of follow-up was 7 years (range, 3 to 17).

Purpose

The purpose of the present study was to compare functional outcomes of medial unicompartmental knee arthroplasty (UKA) in patients with lateral meniscal lesion (LM (+) group) in the preoperative MRI and those without lateral meniscal pathology (LM (−) group) and to evaluate the effect of lateral meniscus lesion in preoperative MR on functional outcomes after UKA.

Methods

The outcomes of 66 knees (LM (+) group) were compared to the outcomes of 54knees(LM (−) group)with a median follow-up of 28 month(range 24–36 months). Clinical outcomes including KS object score, KS pain score, lateral side pain, physical exam for lateral meniscal lesion and squatting ability. Radiological parameters (mechanical axis and component position) were compared and their effects on functional outcomes were evaluated at the final follow-up visits.

Introduction

Total hip arthroplasty (THA) is the most common surgery performed for complications of bipolar arthroplasty. The present study evaluated the functional results and complications associated with this surgery.

Patients and Methods

Forty eight hips (48 patients) who had conversion of bipolar arthroplasty to THA between 1998 June and 2013 June, and who were followed-up for more than one year were evaluated. Twenty one hips had conversion surgery to THA using a Fitmore cup with metal-on-metal articulation (28 mm head). Six hips had surgery using the SecurFit cup and three hips, using the Lima LTO cup with ceramic-on-ceramic articulation (28 mm or 32 mm head). Eighteen hips had surgery using a large head metal-on-metal bearing: –MMC (seven hips), ACCIS (six hips) and Magnum (five hips). The average time of follow-up duration was 3.9 years (range, 1.0–11.3). There were 22 men and 26 women between the ages of 28 and 80 years (average, 68.9 years) at the time of conversion surgery. Conversion arthroplasty was performed for acetabular erosion without femoral stem loosening in 19 hips, acetabular cartilage erosion with femoral stem loosening in 13 hips, periprosthetic fracture in 12 hips, and recurrent dislocation in four hips. Results were evaluated using Harris hip score (HHS) and Western Ontario McMaster Universities Osteoarthritis Index (WOMAC) score. The radiographs were analyzed for evidence of acetabular and femoral osteolysis or loosening. The complications were evaluated.

Purpose

The purpose of this study was to evaluate the postoperative maximal flexion of Robotic assisted TKA which does not increase the posterior condylar offset after surgery and compare CT and conventional radiography in measuring the posterior condylar offset changes.

Materials and method

50 knees of 37 patients who underwent Robotic TKA and underwent follow-up minimal one year were evaluated. CT based preoperative surgical planning system was designed not to increase posterior condylar offset (PCO) after surgery. Maximal flexion angle of the knee was evaluated at 1 year after surgery. The change in PCO and joint line on x-ray and CT were evaluated.

Purpose

The purpose of this study is to investigate the relationship between the angles made by the reference axes on the computerized tomography (CT) images and comparison of the knee alignment between healthy young adults and patients who is scheduled to have total knee arthroplasty.

Materials and Methods

This study was conducted in 102 patients with osteoarthritis of knee joint who underwent preoperative computerized tomography (CT). The control group included 50 patients having no arthritis who underwent CT of knee. Axial CT image of the distal femur were used to measure the angles among the the anteroposterior (AP) axis, the posterior condylar axis (PCA), clinical transepicondylar axis (cTEA) and the surgical transepicondylar axis (sTEA). Then, the differences in amounts of rotation between normal and osteoarthritic knee was evaluated.

Introduction

Total knee replacement (TKR) implant designs and materials have been shown to have a significant impact on tibial insert wear. A medial-pivot (MP) design theoretically should generate less wear due to a large contact area in the medial compartment and lower contact stresses. Synovial fluid aspiration studies have confirmed that a first generation MP TKR system (ADVANCE®, MicroPort Orthopedics Inc., Arlington, TN, USA) generates less wear debris than is seen with other implant designs articulating against conventional polyethylene (CP).

Objectives

The objective of this study was to evaluate the in vitro wear rate of a second generation MP TKR system (EVOLUTION® Cruciate-Sacrificing, MicroPort Orthopedics Inc., Arlington, TN, USA) using CP tibial inserts and compare to previously published values for other TKR designs with CP and first or second generation crosslinked polyethylene (XLPE) tibial inserts.

Introduction

The success of cementless total hip arthroplasty (THA), primary as well as for revision, largely depends on the initial stability of the femoral implant. In this respect, several studies have estimated that the micromotion at the bone-implant interface should not exceed 150µm (Jasty 1997, Viceconti 2000) in order to ensure optimal bonding between bone and implant. Therefore, evaluating the initial stability through micromotion measurements serves as a valid method towards reviewing implant design and its potential for uncemented THAs.

In general, the methods used to measure the micromotion assume that the implant behaves as a rigid body. While this could be valid for some primary stems (Østbyhaug 2010), studies that support the same assumption related to revision implants were not found.

The aim of this study is to assess the initial stability of a femoral revision stem, taking into account possible non-rigid behaviour of the implant. A new in vitro measuring method to determine the micromotion of femoral revision implants is presented. Both implant and bone induced displacements under cyclic load are measured locally.

Methods

A Profemur R modular revision stem (MicroPort Orthopedics Inc. Arlington, TN, United States of America) and artificial femora (composite bone 4th generation #3403, Sawbones Europe AB, Malmö, Sweden) prepared by a surgeon were used.

The micromotions were measured in proximal-distal, medial-lateral or anterior-posterior directions at four locations situated in two transverse planes, using pin and bushing combinations. At each measuring location an Ø8mm bushing was attached to the bone, and a concentric Ø3mm pin was attached to the implant [Fig.1 and 2]. A supporting structure used to hold either guiding bushings or linear variable displacement transducers (LVDT) is attached to the proximal part of the implant. The whole system was installed on a hydraulic force bench (PC160N, Schenck GmbH, Darmstadt, Germany) and 250 physiological loading cycles were applied [Fig.3].

Introduction

Dual-mobility (DM) liners have increased popularity due to the range of motion and stability provided by these implants. However, larger head diameters have been associated with anterior hip pain, due to surrounding soft-tissue impingement, particularly the iliopsoas. To address this, an anatomically contoured dual mobility (ACDM) liner was designed by reducing the volume of the liner below the equator (Fig1). Previous cadaver studies have shown that the ACDM significantly reduces iliopsoas tenting and trapping of the liner compared to conventional designs. We created a finite element study based on previous cadaver testing to further analyze the effectiveness of the ACDM design in reducing soft-tissue impingement, specifically the tendon-liner contact pressure and the tendon stress.

Methods

The finite element model was developed within COMSOL 4.3b. The psoas tendon was modelled as a Yeoh hyper-elastic Material, which uses 3 constants (c1-c3), density (1.73g/cm3) and a bulk modulus (26GPa)[Hirokawa,2000]. In a previous, separate study, the average stiffness of 10 psoas tendon samples (5 cadavers), were measured to be 339[N/mm] in the linear region with average width and thickness of 14mmX4mm. The 3 constants were tuned to match experimental uniaxial test data, and were 5[GPa], 0[Gpa], and 46[GPa] for c1, c2, and c3 respectively.

The implant components were rigidly modeled relative to the psoas. Cadaver specific CT models were used to create the FEA geometry. The insertion points for the Psoas were digitally determined on the proximal end of the lesser trochanter, and the psoas notch on the pelvis for hip flexion angles of −15°, 0°, 15° and 30°. These insertion points determined the length of the psoas and its relative position to the femoral head in 3D. The specific liner size and position for each cadaver was determined by implant planning with the CT models. In this abstract, we only present data for 2 specimens (left/right hips) with 44mm conventional DM, and 44mm ACDM, matching specimen anatomy. A 500N tensile load was applied to the psoas tendon proximally to simulate moderate physiological loading, the average/max stresses and contact pressures between the psoas and the two liner designs were determined.

Introduction

The complex cellular mechanisms of the aseptic loosening of total joint arthroplasties still remain not completely understood in detail. Especially the role of adherent endotoxins in this process remains unclear, as lipopolysaccharides (LPS) are known to be very potent modulators of the cell response on wear particle debris. Contributing factors on the LPS affinity of used orthopedic biomaterials as their surface roughness have to be investigated. The aim of this study was to evaluate the affinity of LPS on the surface roughness of different biomaterials in vitro. The hypothesis of the study was that rough surfaces bind more LPS than smooth surfaces.

Materials and methods

Cubes with a side length from ultra-high-molecular-weight-polyethylene (UHMWPE), crosslinked polytethylene (XPE), carbon fibre reinforced poly-ether-ether-ketone (CFR-PEEK), titanium, titanium alloy, Polymethyl methacrylate (PMMA), implant steel (CoCr) and instrument steel (BC) were produced (figure 1). Cubes of each material have been produced with a rough and a smooth surface. Before the testings, all cubes and used materials were treated with E-Toxa-Clean(®) to eliminate pre-existing LPS on the used surfaces. The cubes were then fixed on the cap of a glass that was filled with a LPS solution with a concentration of 5 IE/ml. After 30 minutes the cube was removed and the LPS concentration in the supernatant was measured. The endotoxin content of each sample was evaluated by a Limulus Amoebocyte Lysate (LAL) - Test (Lonza, Verviers, Belgium). The detection level of endotoxin was set at < 0.005 EU/ml diluted 1/10.

Introduction

Patient-specific instrumentation (PSI) is a contemporary method to optimize accuracy of alignment in total knee arthroplasty (TKA). As the potential benefits come at the cost of increased economic and logistic expenses, there is great scientific and practical interest in the actual advantages and reliability of such systems. Therefore, the purpose of the present study was to compare clinical results, radiological limb alignment, and three-dimensional (3D)-component positioning between conventional instrumentation (CVI) and a computed tomographic (CT)-based PSI in primary TKA.

Methods

Two-hundred-ninety consecutive patients (300 knees) with severe, debilitating osteoarthritis scheduled for TKA were included in this study using either CVI (n=150) or PSI (n=150). Patients were clinically assessed according to the Knee Society Score (KSS), range of motion (ROM), and visual analog scale for pain (VAS) before and two years after surgery. Hip-knee-ankle angle (HKA) and 3D-component positioning were assessed on postoperative radiographs and CT to evaluate accuracy of CVI and PSI.

Background

Tranexamic acid is an antifibrinolytic drug that has been shown to successfully reduce postoperative blood loss in total knee and hip arthroplasty. However, the efficacy of TXA following total shoulder arthroplasty has not been reported.

Purpose

The purpose of the present study was to evaluate the impact of intravenous TXA on postoperative blood loss and transfusion rates in total shoulder reconstruction.

BACKGROUND CONTEXT

Ceramic bearings are widely used in total hip arthroplasty (THR) along with metal and polyethylene bearings. There were several studies in past few years evaluating the advantage of one over the other. The young population with high activity levels has an increased risk of wear debris production at bearing surface and subsequent implant failure. Recently, interest and use of a ceramics with high wear resistance has been growing. Early reports on ceramic on ceramic THR have demonstrated excellent clinical and radiological results.

PURPOSE

To evaluate clinical, functional and radiological outcomes of cement-less ceramic on ceramic primary total Hip Replacement (THR) in young patients (<50 years age) with diagnosis of avascular necrosis femoral head.

INTRODUCTION

Trabecular Titanium is an open-cell regular structure composed by hexagonal cells of controlled pore, manufactured by Electron Beam Melting (EBM) technology, that allows moulding of cellular solid structures. The Lima Delta TT revision cups are One and Revision, which is characterized by a caudal hook and fins. Both allow internal modularity and cranial TT augments.

The aim of this prospective study is to evaluate the short to medium-term clinical and radiographic outcomes of acetabular revision cups in TT.

METHODS

Between December 2008 and March 2013 we performed 60 cup revisions, 33 with the Revision cup and 27 with the One cup.

The bone defect was classified according to Paprosky acetabular classification: type IIb and IIc presenting continent anterior and posterior acetabular wall were treated by Delta One TT; type IIIa and IIIb were treated with Delta TT Revision. In 20 cases (3.3%) stem revision was associated. Causes of revision were: aseptic loosening in 48 cases, periprosthetic acetabular fractures in 5 cases, recurrent dislocation in 5 cases, infection in 2 cases. In 52 cases bone grafts were used to fill cavitary defects (AIR 1–4). Hemispheric TT augments were used in 13 cases with the same aim. Internal modules were used in 39 cases to restore correct offset. The mean age of patients was 69.6 years (range 29–90). The average follow-up was 39 months (range 19–70).

Introduction

In total hip arthroplasty (THA), polyethylene (PE) liner oxidation leads to material degradation and increased wear, with many strategies targeting its delay or prevention. However, the effect of femoral head material composition on PE degradation for ceramic-PE articulation is yet unknown. Therefore, using two different ceramic materials, we compared PE surface alterations occurring during a series of standard ceramic-PE articulation tests.

Materials and Method

Ceramic-PE THA bearings were tested in a simulator, using ASTM F2003-02, ASTM F1714-96 (2013) and ISO 14242:1–3 standards. Acetabular liners (Apex-Link PolyTM, OMNI Life Science, East Taunton, MA, USA) were articulated against Ø28 mm Si3N4 femoral heads (Amedica Corp., Salt Lake City, UT, USA). For comparison, ArCom® PE liners (Biomet Inc. Warsaw, IN, USA) were also tested against Ø28 mm zirconia-toughened alumina (ZTA) femoral heads (BIOLOX®delta, CeramTec GmbH, Plochingen, Germany), under the same conditions. After 5 million cycles of wear, all specimens were examined using nano-spectroscopy tools. Evaluations were performed on six couples per group, plus 3 untested control couples; n= 6 (+3). Spectrographic examinations generated 8 maps of 400 points each randomly selected on the wear zones of each liner, with each map area being 20 µm2 at an in-plane spatial resolution of 1 µm.

Introduction

The primary purpose of Total Hip Arthroplasty (THA), aside from pain relief, is to restore hip biomechanics such that the patient experiences no discernible functional deficit, while also providing an environment conducive to implant longevity. Key factors in determining a successful THA include achieving the desired pre-operative femoral offset and leg length, as well as the restoration of range of motion (ROM). Minor leg length discrepancies (LLDs), less than a centimetre, are common after THA and usually well tolerated. However, in some patients, even these small discrepancies are a source of dissatisfaction. More significant discrepancies can be a risk factor for more serious concerns such as nerve injury, abnormal gait and chronic pain. The level of the femoral neck osteotomy is a critical step in reproducing a planned femoral stem position. Frequently the femoral osteotomy is too high and can lead to an increase in leg length and varus stem positioning. If the desired implant positions are identified from preoperative 3D templating, a planned femoral osteotomy can be used as a reference to recreate the correct leg length and offset. The aim of this study was assess the accuracy of a 3D printed patient-specific guide for delivering a pre-planned femoral neck osteotomy.

Methodology

A consecutive series of 33 patients, from two surgeons at a single institution, were sent for Trinity OPS pre-operative planning (Optimized Ortho, Australia). Trinity OPS is a pre-operative, dynamic, patient-specific modelling system for acetabular and femoral implant positioning. The system requires a pre-operative CT scan which allows patient specific implant sizing as well as positioning. Once the preoperative implant positioning plan was confirmed by the surgeon, a patient-specific guide was designed and printed to enable the planned level of femoral neck osteotomy to be achieved, Fig 1. All patients received a Trinity cementless acetabular component (Corin, UK) and a cementless TriFit TS femoral component (Corin, UK) through a posterior approach. The achieved level of osteotomy was confirmed postoperatively by doing a 3D/2D registration, in the Mimics X-ray Module (Materialise, Belgium), of the planned 3D resected femur to the postoperative AP radiograph, Fig 2. The image was then scaled and the difference between the planned and achieved level of osteotomy was measured (imatri Medical, South Africa), Fig 2.

Introduction

Acetabular cup orientation has been shown to be a factor in edge-loading of a ceramic-on-ceramic THR bearing. Currently all recommended guidelines for cup orientation are defined from static measurements with the patient positioned supine. The objectives of this study are to investigate functional cup orientation and the incidence of edge-loading in ceramic hips using commercially available, dynamic musculoskeletal modelling software that simulates each patient performing activities associated with edge-loading.

Methodology

Eighteen patients with reproducible squeaking in their ceramic-on-ceramic total hip arthroplasties were recruited from a previous study investigating the incidence of noise in large-diameter ceramic bearings. All 18 patients had a Delta Motion acetabular component, with head sizes ranging from 40 – 48mm. All had a reproducible squeak during a deep flexion activity. A control group of thirty-six patients with Delta Motion bearings who had never experienced a squeak were recruited from the silent cohort of the same original study. They were matched to the squeaking group for implant type, acetabular cup orientation, ligament laxity, maximum hip flexion and BMI. All 54 patients were modelled performing two functional activities using the Optimized Ortho Postoperative Kinematics Simulation software. The software uses standard medical imaging to produce a patient-specific rigid body dynamics analysis of the subject performing a sit-to-stand task and a step-up with the contralateral leg, Fig 1. The software calculates the dynamic force at the replaced hip throughout the two activities and plots the bearing contact patch, using a Hertzian contact algorithm, as it traces across the articulating surface, Fig 2. As all the squeaking hips did so during deep flexion, the minimum posterior Contact Patch to Rim Distance (CPRD) can then be determined by calculating the smallest distance between the edge of the contact patch and the true rim of the ceramic liner, Fig 2. A negative posterior CPRD indicates posterior edge-loading.

Background

The use of reverse total shoulder arthroplasty considerably increased since first introduced by Paul Grammont in the late 1980s. Over the past few years, results from several mid- and long-term clinical studies have demonstrated good functional outcomes and pain relief. However, several complications, especially inferior glenoid notching, and high revision rates were reported in the literature. Improvements in prosthesis design should contribute to a lower complication rate and lesser amount of glenoid erosion. Few studies have reported the clinical outcome andcomplications of Anatomical Shoulder Inverse/ Reverse Prosthesis. This study documents 2- and 6-year clinical and radiological results following reversed shoulder arthroplasty using this novel prosthesis.

Methods

We report the results for sixty-eight consecutive patients (seventy shoulders) with cuff tear arthropathy (CTA) treated with Anatomical Shoulder Inverse/Reverse Prosthesis between 2006 and 2008. Two groups were defined: (A) primary treatment and (B) revision. Clinical evaluation tools comprised Constant-Murley score (CS), range of motion, and a visual analog scale to assess pain. Radiographs (anteroposterior view in neutral position) were evaluated for notching and radiolucent lines. Any complications were recorded.

Introduction

Third body wear caused by contaminated bearing environment with debris that may have been generated by a worn or fractured revised bearing coupling, but also originated by generation of metal/cement particles during the primary or revision surgery, may be a relevant issue for the implant life.

Objectives

To evaluate the wear behavior of a last generation alumina matrix ceramic composite (AMC) bearing in a worst case scenario consisting of highly contaminated test lubricant with alumina particles in a hip joint simulator study.

INTRODUCTION

Wear, aseptic loosening, dislocation, corrosion and prosthetic joint infection (PJI) are major factors leading to revision of THA. The effect of using ceramic components to address these issues was investigated to determine their behaviour and potential benefit.

METHODS

Introduction

The legacy constrained condylar knee prosthesis (LCCK, Zimmer.) is designed for primary and revision total joint arthroplasties that need additional stability due to ligament deficiency and to compensate for bone defects. In this follow-up we present our mid term results.

Methods and Material

Between November 1999 and January 2006 59 patients were provided with 67 LCCK knee endoprotheses. 38 prostheses were implanted in cases of revision surgery and 29 as primary implants. The mean patient age was 76 years (range 22–93). Indications for revisions were 20 aseptic loosenings, 11 late infections, 7 instabilities (5 cases due to polyethylene wear). Indications for primary arthroplasties were 16 severe valgus and 7 severe varus deformities, 5 cases of osteoarthritis after infection and 1 posttraumatic deformity. 36 femur components (54%) and 34 tibia components (51%) were augmented. 31 stems were fixed cementless, 15 stems were cemented (6 with an intermedullary plug). We evaluated the results prospectively with a clinical inspection and x-ray. Clinical rating systems used were the Knee society, SF-36 Quality of life and Womac score. The mean follow up was 5.6 years. 42 patients were examined, 10 questioned on the telephone, 3 deceased, 12 had to be revised and 2 were lost for follow-up.

BACKGROUND

The most common salvage of a failed metal-on-metal hip resurfacing is to remove both the femoral and acetabular resurfacing components and perform a total hip replacement. The other choices are to perform an acetabular or femoral only revision. A one or two piece acetabular component or a polyethylene bipolar femoral component that matches the retained metal resurfacing acetabular component is used. The considerations in favor of performing a one component resurfacing revision are maintaining the natural femoral head size, limiting the surgical effort for the patient and surgeon, and bone conservation. There are often favorable cost considerations with single component revision surgery.

The reasons for femoral component revision are femoral neck fracture, femoral component loosening and an adverse reaction to metal wear debris. Performing a femoral component only revision requires a well fixed and well oriented acetabular component. Acetabular revision is most often performed for an adverse reaction to metal wear debris or loosening.

METHODS

81 acetabular revisions and 46 femoral revisions were evaluated 4 to 14 years after surgery. 83% of patients had their initial surgery at outside institutions. The mean age was 46 and 65% of patients were women. A two piece titanium backed polyethylene component was used in 44 patients and a one or two piece metal component was used in 37. A dual mobility femoral prosthesis mated to a retained metal acetabular component was used for the femoral revisions and no conversions to a metal-on-metal total hip replacement were performed. We selected polyethylene acetabular components for patients with adverse reactions to metal wear debris if their femoral component was less than 48 mm or if there was no matching metal acetabular component available for their femoral component. We used dual mobility components for femoral loosening, femoral neck fractures and adverse reactions to metal wear debris in patients with well-fixed and well oriented metal acetabular components. Dual mobility components were also used if there are any concerns about the femoral component or in some older patients. We performed one component revisions rather than conversion to total hip replacement on 88% of patients presenting with failed resurfacing prostheses.

BACKGROUND

We originally performed metal-on-metal hip resurfacing using a Townley designed Vitallium Total Articular Replacement Arthroplasty (TARA) curved stemmed prosthesis. Neither the acetabular or femoral components were cemented or had porous coating. The bearing surfaces were consistently polar bearing. The surgical objectives were to preserve bone stock, maintain normal anatomy and mechanics of the hip joint and to approximate the normal stress transmission to the supporting femoral bone. The functional objectives were better sports participation, less thigh pain and limp, less perception of a leg length difference and a greater perception of a normal hip. Metal-on-metal was selected to conserve acetabular bone and avoid polyethylene associated osteolysis.

Relatively few cases were performed until the Conserve Plus and later the Birmingham Hip Resurfacing systems became available.

METHODS

We examined the results of metal-on-metal hip resurfacing in patient with at least 10 years of follow-up and an age less than 50 at the time of surgery. We did not have access to the Birmingham Prosthesis until 2006. We performed 101 TARA procedures and 397 Conserve Plus procedures for 357 patients. For the combined series the mean age was 43 and 62% of patients were male. 34 patients had a conventional total hip replacement on the contralateral side. We used both the anterolateral and posterior approaches. All acetabular components were placed without cement and all the Conserve Plus Femoral Components were cemented.

Background

Cross-linked polyethylene has much less wear than conventional polyethylene and can used in a more bone conserving thickness of 4 mm. We have used it for hip resurfacing since 2001.

Questions/Purposes

This study evaluated the effectiveness of a highly cross-linked polyethylene acetabular component for hip resurfacing in patients under age 50. I posed 5 questions: (1) What are the functional results, (2) What are the complications, (3) What is the 10-year implant survivorship, (4) What is the femoral head penetration into the polyethylene, and (5) What is the bone conservation?

BACKGROUND PURPOSES

dislocation is a classical complication in total hip arthroplasty (THA) revision. Cup fixation is the second concern. Since 1998 we routinely use cementless Dual mobility cup (DMC) in revision surgery. In order to know outcomes at 2 years, we followed a prospective series of 78 patients treated in our institution. Purpose is to demonstrate that DMC used in revision THA is safe as regards dislocation risk and bone fixation.

MATERIAL METHODS

from January 2010 to January 2012 we collected cohort of 79 cases on 78 patients. Patients have been followed with a clinical and radio graphical standard examination. Mean delay between index surgery and revision was 12,9 years. Mean age at revision was 75,5 years. Two different types of DMC were used: standard DMC in 68 cases. In severe bone loss, a specific revision cup was used in 11 cases.

Aim

Computer-navigated total knee arthroplasty has been shown to improve the outcome in outliers with consistent results. The aim of this study is to evaluate the clinical and radiographic outcomes of computer-navigated knee arthroplasty with respect to deformity and body mass index (BMI).

Materials and Methods

Data was prospectively collected for 117 consecutive patients undergoing primary computer-navigated total knee arthroplasty using Ci Brainlab system with J&J PFC PS implants by a single surgeon utilising a tibia cut first, gap-balancing technique. Pre-operative and post-operative long-leg films, weight-bearing, films were taken and the long-axis was measured by a single observer. Intra-operative computer navigation long-axis values were stored as screenshots intra-operatively after registration and after implant was cemented. BMI, range of motion (ROM), SF 36 and Oxford knee scores were recorded both before surgery and on follow-up. Minimum 2-year follow-up. Eight patients were lost to follow-up and 8 had incomplete 2 year data. Data was analysed using the Chi-squared test for categorical variables and the t-test for continuous variables.

Introduction

BAG-S53P4 has similar mechanical properties as cortical bone tissue and can be used as an additive to bone allografts. The aim of this study was to evaluate the effect of adding BAG-S53P4 to chemically treated allografts with controlled grain size distribution.

Methods

Allografts were prepared and chemically cleaned under sterile conditions. 30 samples were mixed with BAG-S53P4 additive (BG) and compared to a control group (CG) with similar grain size distribution and composition in weight. All samples underwent a uniaxial compression test after compaction with a dropped weight apparatus. The yield limit was determined by a uniaxial compression test and density was recorded. The two groups were tested for statistical differences with the student's t-Test.

Introduction

Stress shielding is one of the major concerns of load bearing implants (e.g. hip prostheses). Stiff implants cause stress shielding, which is thought to contribute to bone resorption1. On the contrary, low-stiffness implants generate high interfacial stresses that have been related to pain and interfacial micro-movements².

Different attempts have been made to reduce these problems by optimizing either the stem design3 or using functionally graded implants (FGI) where the stem's mechanical properties are optimized4. In this way, new additive manufacturing technologies allow fabricating porous materials with well-controlled mesostructure, which allows tailoring their mechanical properties.

In this work, Finite Element (FE) simulations are used to develop an optimization methodology for the shape and material properties of a FGI hip stem. The resorbed bone mass fraction and the stem head displacement are used as objective functions.

Methodology

The 2D-geometry of a femur model (Sawbones®) with an implanted Profemur-TL stem (Wright Medical Technology Inc.) was used for FE simulations. The stem geometry was parameterized using a set of 8 variables (Figure 1-a). To optimize the stem's material properties, a grid was generated with equally spaced points for a total of 96 points (Figure 1-b).

Purely elastic materials were used for the stem and the bone. Two bone qualities were considered: good (Ecortical=20 GPa, Etrabecular=1.5 GPa) and medium (Ecortical=15 GPa, Etrabecular=1 GPa). Poisson ratio was fixed to v=0.3. Loading corresponded to stair climbing. Hip contact force along with abductors, vastus lateralis and vastus medialis muscles were considered5 for a bodyweight of 847 N.

The resorbed bone mass fraction was evaluated from the differences in strain energy densities between the intact bone and the implanted bone2. The displacement of the load point on the femoral head was computed.

The optimization problem was formulated as the minimization of the resorbed bone mass fraction and the head displacement. It was solved using a genetic algorithm.

Introduction

Periprosthetic joint infection (PJI) is considered one of the most feared causes of implant failure, due to the difficulty in formulating a proper and timely diagnosis. In the diagnostic workup are often used test with a low specificity, such as the dosage of ESR and CRP, or sensitivity, such as cultures or the leukocyte count of the synovial fluid. Radiological investigations are expensive and unreliable to play a direct role in the diagnosis of PJI. The alpha-defensin is an antimicrobial peptide released by neutrophils in response to pathogens and it is an ideal biomarker for the diagnosis of PJI. It is now possible to verify the presence of alpha-defensin in periprosthetic synovial fluid with an ELISA (Synovasure® PJI, Zimmer) that provides results in 10 minutes, with a sensitivity of 97% and a specificity of 96%, without being affected by systemic inflammatory diseases or by the assumption of antibiotics. The purpose of this study is to assess the applicability and reliability of Synovasure® PJI, correlating its results with microbiological analyzes, laboratory tests and imaging studies of the patient.

Materials and Methods

Patients recruited are those who have undergone a previous total hip or knee arthroplasty where there is suspicion of PJI. The test can be performed either during surgery or during the diagnostic iter, through the execution of an arthrocentesis. The synovial fluid is partly used for Synovasure® PJI and partly put in culture for microbiological analyzes. Once ready, culture results are compared with the results of the test to get a confirmation of its reliability or reference to identify the microorganism responsible for PJI. These data are then compared, with laboratory tests and radiological investigations performed by the patient.

Introduction

Cementless stems are fixed to the surrounding bone by means of mechanical press-fit. Short-, mid-, and long term outcomes are good for this type of fixation despite that only a part of the stem surface is in contact with the surrounding bone. Several studies show that the contact ratio achieved after surgery between the stem and the surrounding bone ranged between 15% and 60%. Then, only a part of the stem-bone interface presents a press-fit. The rest of the stem-bone interface is only in contact or presents an interfacial gap inherent to the surgical technique. Therefore, this study aimed to investigate the difference in the primary stability of a cementless stem between a press-fit combined with contact and a press-fit combined with gap achieved after the surgery.

Materials & Methods

A finite element study was carried out on a composite bone implanted with a femoral stem and subjected to physiological loading simulating stair climbing [1]. All materials were defined as isotropic homogeneous. The stem-bone interface was divided into 4 areas: the superior plasma spray, the inferior plasma spray, the polished surface of the stem in contact with the cancellous bone, and the plasma spray surface of the stem in contact with the cortical bone. Each contact area can be either in contact with a press-fit, either in contact without press-fit or can present a gap. This result in a total of 28 cases: 14 where there is a press-fit combined with contact and 14 cases where there is a press-fit combined with gap.

INTRODUCTION

Total joint arthroplasty continues to gain acceptance as the standard of care for the treatment of severe degenerative joint disease, and is considered one of the most successful surgical interventions in the history of medicine. However, infection of these implants, called Periprosthetic Joint Infection (PJI), remains one of the biggest challenges facing orthopaedics today. PJI can lead to additional surgeries, revision, fusion and amputation.

Introduction

According to the Australian registry 2014, periprosthetic joint infection (PJI) is the fourth important reason for revision of a primary total hip arthroplasty (THA). PJI is frequently caused by commensal strains of the skin such as Staphylococcus aureus or Staphylococcus epidermis. Deep infection is depending on many factors, such as implant surface chemical and physical behaviour, device design, host site, surgery and host response. Nevertheless, a lack of knowledge is seen concerning the specific effects of different surfaces on the biological response of different biomaterials. In addition, it is difficult to discriminate the material chemico-physical properties by the topological features, such as surface roughness. Indeed, it has been widely demonstrated that surface composition, electric charge, wettability and roughness of implant surfaces have a strong influence on their interactions with biological fluids and tissues. Therefore, also bearing surface properties can influence the incidence of PJI, just shown recently.

Objectives

To verify the capability of ceramic bearings to reduce bacteria biofilm adhesion by means of their surface chemico-physical properties.