Introduction

Proper femoral reaming is a key factor for a successful outcome in cementless hip arthroplasty. Good quality reaming minimizes risks of intra-operative femoral fracture during reaming and prevents poor fitting of the implant which can lead to subsidance of the stem postoperativly. Determining the quality of reaming is largely a subjective skill and dependant on the surgeon's experience with no documented intraoprative method to assess it objectively.

Method

We recorded and analysed the frequencies of sound signals recorded via a bone conduction microphone during reaming of the femoral canal in a series of 28 consecutive patients undergoing uncemented total hip replacement performed by same surgeon. Hammaring sound frequencies and intensity were analysed by mean of computer software. The relationship between the patterns of the recorded reaming sound frequencies compared with surgeon judgment of the reaming quality intraoparativly and post operative x rays. All patients were followed up clinically and radiologically for 2 years after surgery to determine the integrity of the fix and to evaluate the stability of the prosthesis.

Introduction

Stripe wear, observed on retrieved ceramic hip replacements, has only been replicated in vitro under translational mal-positioning conditions where the centres of rotation of the head and the cup are mismatched^1,2; an in vitro condition termed “microseparation”.

The aim of this study was to compare the edge loading mechanisms observed under microseparation conditions due to translational mal-positioning conditions simulated on two different hip joint simulators.

Materials and Methods

The components used in this study were zirconia-toughened-alumina ceramic-on-ceramic bearings (36 mm) inserted into titanium alloy acetabular cups (BIOLOX® delta and Pinnacle® respectively, DePuy Synthes Joint Reconstruction, Leeds, UK). Six couples were tested for two million cycles under 0.5 mm dynamic microseparation conditions on the Leeds II hip joint simulator as described by Nevelos et al² and Stewart et al³ (Figure 1). Ten bearing couples were tested for two million cycles under microseparation conditions achieved in two different ways on the ProSim pneumatic hip joint simulator (SimSol, Stockport, UK). Two conditions were tested; condition (1)- the femoral head was left to completely separate (the vertical motion was controlled at 1 mm) causing it to contact the inferior rim of the acetabular cup before edge loading on the superior rim at heel strike (n = 5) and condition (2)- springs were placed below the plate holding the femoral head to control the tilt of the head laterally towards the rim of the acetabular cup as the negative pressure was applied (n = 5; Figure 1). Wear was assessed gravimetrically every million cycles using a microbalance (Mettler AT201, UK). Three-dimensional reconstructions of the wear area on the heads were obtained using a coordinate measuring machine (Legex 322, Mitutoyo, UK) and SR3D software (Tribosol, UK).

Background:

It is not well known how different external loads influence shoulder kinematics and muscle activity in patients with shoulder prostheses. Study objective: define shoulder kinematics and determine the scapulothoracic contribution to total shoulder motion, in combination with shoulder muscle activity and the degree of co-contraction, of patients with total (TSA) and reverse shoulder arthroplasties (RSA) and healthy individuals during rehabilitation exercises using different loading conditions.

Methods:

Shoulder motions (anteflexion and elevation in the scapular plane) of 17 patients (20 shoulders) with a TSA, 8 patients (9 shoulders) with a RSA and 15 healthy subjects were measured using anelectromagnetic tracking device. A force transducer recorded force signals during loaded conditions (without external load, 1 kg and elastic resistance). Electromyographic (EMG) activity of the deltoid (anterior, middle, posterior parts), latissimus dorsi, pectoralis major (clavicular and sternal parts), teres major and serratus anterior was recorded and the degree of co-contraction calculated.

Background:

Higher than expected revision rates have been observed in large bearing metal-on-metal total hip replacements. We have introduced a metal on metal hip screening clinic at our unit and report the results.

Methods:

All patients who had a metal-on-metal total hip replacement implanted at our unit were recalled to clinic. Screening consisted of clinical examination, Oxford hip score, radiographs, MARS MRI and serum cobalt/chromium ion levels. MRI scans were graded (Norwich Classification) by a single consultant radiologist who was blinded to the history, examination, and metal levels. Patients were sub-classified into 6 groups, which determined further follow up and were either entered into a regular screening programme or referred to a revision arthroplasty surgeon for a decision on whether revision was required

Background:

Total knee replacement (TKR) is a frequent and effective surgery for knee osteoarthritis. Postoperative pain is under concern and can be relieved by different methods, including femoral nerve block (FNB). The efficacy of FNB on pain relief was associated with the absence of clinical impact when measured with the range of motion (ROM). Recent studies suggest that the quadriceps strength is the best indicator of functional recovery after TKR. The goal of this study is to compare the quadriceps strength recovery after TKR according to the kind of analgesia (patient control analgesia (PCA) with or without FNB) Hypothesis: the FNB delays the QSR at short and mid-term follow-up.

Methods:

Prospective randomized trial with single-blind assessment involving 135 patients admitted for TKR in an academic center. Randomization into one of the three following groups: A) Continuous FNB 48h + PCA B) Single-shot FNB and PCA C) PCA alone. Groups were comparable for demographic and surgical data. The FNB was realised and controlled (electric stimulation) by an expert anesthesiologist before the surgery. Follow-up standardised in all groups with blinded assessors. Quadriceps strength measured with a validated dynamometer at 6 weeks, 6 and 12 months. Secondary outcomes included clinical evaluation (ROM, pain, stability) and functional scores (SF-36 v2, WOMAC). Multivariate analysis (Kruskal-Wallis, Mann-Whitney) for main outcomes and Spearman factor for correlation. Sample size calculated for alpha 5% and study power 80%.

Introduction

Clinical outcomes for total knee arthroplasty (TKA) are especially sensitive to lower extremity alignment and implant positioning.¹ The use of computer-assisted orthopedic surgery (CAOS) can improve overall TKA accuracy.² This study assessed the accuracy of an image-free CAOS guidance system (Exactech GPS, Blue-Ortho, Grenoble, FR) used in TKA.

Materials and methods:

A high-resolution 3D scanner (Comet L3D, Steinbichler, Plymouth, MI) was used to scan seven knee models (MITA, Medical Models, Bristol, UK) and collect pre-identified anatomical landmarks (see Figure 1) prior to using the models to simulate knee surgery.

The image-free CAOS guidance system was then used to acquire the same landmarks. After adjusting the position and orientation of the cutting block to match the targets, bone resections were performed, and the knee models were re-scanned. The 3D scans made before and after the cuts were overlaid (see Figure 2) and the resection parameters calculated using the pre-identified anatomical landmark data and advanced software (XOV & XOR, RapidForm, Lakewood, CO and UG NX, Siemens PLM, Plano, TX). Data sets obtained from the 3D scanner were compared with data sets from the guidance system. Given the accuracy of the 3D scanner, its measurements were used as the baseline for assessing CAOS system error.

Introduction:

Recent studies have concluded that gender influences hip morphology at the time of surgery as well as dysplastic development of the hip. This may lead to a particular choice of implant including stem design and/or neck modularity. In this study we hypothesized that not only gender but also morphotype and etiology (primary osteoarthritis versus aseptic osteonecrosis) may be a significant factor to predict the anatomy of the hip at the time of total hip arthroplasty (THA).

Methods:

We reviewed 690 patients undergoing THA for primary arthritis (OA) or avascular osteonecrosis (AVN) between April 2000 and June 2005 and stratified each into three groups based on their anatomic constitution: endomorph (EN), ectomorph (ECT), or mesomorph (ME) (determined by the ratio: pelvic width/total leg length measured on full-length X-rays). Two independent observers measured twice four parameters on preoperative CT scan: neck-shaft-angle angle (NSA), femoral offset value (FO), helitorsion (Ht) value and femoral neck anteversion (Av).

Introduction:

To date, there have been few reports of the results of revisions for failed metal-on-metal hip arthroplasties (MoM HA's). These series have included relatively modest numbers, and classification of the severity of adverse local tissue reaction (ALTR) has been under-reported. In this study, early outcomes and complications are analyzed as a function of pre-operative MRI grade and intra-operative ALTR severity to determine their prognostic value.

Methods:

This is a retrospective review of revisions of 121 failed MoM HA's performed between 2008 and 2012. Indications for revision include ALTR (n = 97), loose cup (n = 13), and combined loose cup and ALTR (n = 11). When pre-operative MRI's were available, these were graded according to Anderson's system by 2 radiologists who were blinded to the clinical results. Intra-operative findings were graded for severity according to an ALTR classification. Post-operative complications were recorded. Correlations between pre-operative MRI grade, intra-operative ALTR classification and post-operative complications were analyzed using Spearman's rank correlation.

ALTR Classification:

Type 0: No abnormal fluid or pseudotumor. Peri-articular structures intact.

Type 1: Abnormal fluid and/or pseudotumor. Peri-articular structures disrupted but repairable.

Type 2: Abnormal fluid and/or pseudotumor. Peri-articular structures disrupted and no meaningful repair possible.

Type 3: Abnormal fluid and/or pseudotumor. Peri-articular structrues disrupted, no meaningful repair possible, AND significant necrosis involving abductor muscles.

Summary:

Smaller increments in the antero-posterior dimensions of femoral components allows significant improvements in balancing of the knee after TKA with restoration of more normal soft-tissue stability.

Introduction:

The soft-tissue stability of the knee after TKA is often compromised by the fact that only a finite set of implantable component sizes is available to match bony anatomy. While this could be overcome with custom components, a more practical solution is a set of femoral components with smaller increments in the antero-posterior (AP) dimension. However, this results in a larger assortment of sizes of both implants and trial components. This study was performed to determine whether smaller increments in the AP sizing of knee prostheses would lead to real benefits in restoration of normal knee function and stability after TKA.

PURPOSE:

Unicompartmental knee arthroplasty (UKA) is becoming more commonly performed and is more technically challenging than total knee replacement. Retention of the anterior and posterior cruciate ligaments requires more accurate re-creation of the patient's normal anatomic posterior slope with UKA. Purpose of this study was to accurately determine the posterior tibial slope in patients having medial or lateral UKA performed.

METHODS:

Retrospective review was performed of 2,395 CT scans performed for a customized UKA implant. Standard CT technique was used and the posterior slope was measured on the involved side of the proximal tibia.

Background

In young patients with femoral neck non-union it is desirable to preserve the femoral head. The objective of this study was to assess the outcome results of revision internal fixation and nonvascular fibular bone grafting

Patients and Methods:

Ten patients with non united fracture neck femur were included in this prospective study. Fixation was done with two cancellous screws leaving behind a space between two screws for fibular strut graft. Assessment of union was done by both clinical and radiological criteria.

Introduction:

Wear particles cause aseptic loosening by stimulating macrophages to produce inflammatory cytokines. Recent studies indicate that Toll-like receptor 2 (TLR2) and TLR4 mediate macrophage responses to the wear particles [1–3]. TLR2 and TLR4 uniquely activate MyD88-dependent signaling via an additional adapter protein known as TIRAP/Mal [4]. Del Vescovo et al reported that three single nucleotide polymorphisms (SNPs) within the TIRAP/Mal gene associate with aseptic loosening in THA patients [5]. The goal of the current study was therefore to determine whether TIRAP/Mal mediates responses to orthopaedic wear particles.

Methods:

Immortalized wild type (WT) and TIRAP/Mal knockout (KO) murine macrophages (Mfs) were incubated in the presence or absence of titanium (Ti) particles (1 × 10⁸ particles/cm² [2]. Three types of particles were used as described previously [1,2]: Ti particles with adherent bacterial debris (38.3 Endotoxin Units/10⁹ particles), endotoxin-free Ti particles (<0.1 EU/10⁹ particles), and Ti particles with adherent lipopolysacharide (LPS, 32.8 EU/10⁹ particles). TNFa, IL-1b, and IL-6 mRNAs were measured by real-time PCR and the secreted cytokines were measured by ELISA. Particle-induced osteolysis in calvaria of TIRAP/Mal KO and WT mice was measured 7 days after particle implantation [1,2]. In vitro results are presented as mean ± SEM of 3–4 replicate experiments analyzed by two-way ANOVA with Bonferroni post-hoc corrections. In vivo results are presented as means of individual parietal bones ± SEM (n = 22) and analyzed by one-way ANOVA on ranks with Student Neuman-Keuls post-hoc corrections. * denotes p < 0.5, ** denotes p < 0.01, *** denotes p < 0.

Introduction:

With the arrival of the 21^st century, there were clear expectations that cementless fixation in total joint replacements (TJR), and the translational animal protocols for introducing new coatings and surface treatments clinically, had been established. Despite the extensive literature in the 1980s and 1990s demonstrating a translational pathway for predicting skeletal attachment, there remain clinical reports of mechanical implant loosening in both cementless total hip acetabular and total knee components. Before screening a new porous coating or surface treatment, it is important to note that there has been only one experimental translational load-bearing model that has had human (1–3), sheep (4–5), clinical (6–8), and implant retrieval verification confirming skeletal attachment in these types of components, the intracondylar model (1–5,8).

What makes the intracondular model predictive of coating or surface treatments for implant attachment is the ability of the model to replicate the healing response of cancellous bone, the main attachment bone tissue to THR acetabular and TKA implants. A lot of the confusion rests with a lack of understanding of the bone response differences between the intracondylar and transcortical animal models.

The goal of this study was to test the hypothesis that the intracondylar model can provide positive and negative surface attachment data, whereas, the transcortical model can only provide positive and false positive attachment data.

Methods:

Five skeletally mature sheep will have been implanted with two 13×8 mm plugs (500 mm larger than the 7.5 mm drilled holes) two plugs transcortically and two intracondylarly. One plug will be titanium with CP porous coating. Another plug is made of petrified dinosaur poop with similar dimensions (see Figure 1). Another five sheep will also be implanted transcortically and intracondylarly using plugs with 500 mm inset of the same materials and dimensions. Again, two implants at each site.

Background:

Patient-specific guiding (PSG) is a relatively new technique for aligning a total knee arthroplasty (TKA). Limited data exist on the precise accuracy of the technique. The purpose of this study is to investigate whether there was significant difference between the alignment of the individual femoral and tibial components (in all three anatomical planes) as calculated pre-operatively and the actually achieved alignment in vivo.

Methods:

Twenty-six patients were included. Software permitted matching of the pre-operative MRI-scan (and therefore calculated prosthesis position) to a pre-operative full-leg CT-scan. After surgery a post-operative full-leg CT-scan could be superimposed onto the pre-operative CT-scan to accurately determine deviations from planning (see figure 1 and 2). This 3D-technique has an accuracy of 0.7–1.0 degrees.

BACKGROUND:

The optimal reference for rotational positioning of femoral component in total knee replacement (TKR) is debated. Navigation has been suggested for intra-op acquisition of patient's specific kinematics and functional flexion axis (FFA).

QUESTIONS/PURPOSES:

To prospectively investigate whether pre-operative FFA in patients with osteoarthritis (OA) and varus alignment changes after TKR and whether a correlation exists between post-op FFA and pre-op alignment.

Introduction:

UKA allows replacement of a single compartment in patients who have isolated osteoarthritis. However, limited visualization of the surgical site and lack of patient-specific planning provides challenges in ensuring accurate alignment and placement of the prostheses. Robotic technology provides three-dimensional pre-op planning, intra-operative ligament balancing and haptic guidance of bone preparation to mitigate the risks inherent with current manual instrumentation. The aim of this study is to examine the clinical outcomes of a large series of robot-assisted UKA patients.

Methods:

The results of 500 consecutive medial UKAs performed by a single surgeon with the use of a metal backed, cemented prosthesis installed with haptic robotic guidance. The average age of the patients at the time of the index procedure was 71.1 years (range was 40 to 93 years). The average height was 68 inches (range 58″–77″) and the average weight was 192.0 pounds (range 104–339 pounds). There were 309 males and 191 females. The follow-up ranges from 2 weeks to 44 months.

Introduction

Optimal alignment of the tibial component in TKA is an important consideration. General agreement exists on the appropriate coronal alignment. However there is no consensus on sagittal alignment (posterior slope). Some surgeons target a fixed posterior slope (usually between 0 and 10 degrees), while others attempt to match the patient's intrinsic anatomy. The purpose of this study was to evaluate the tibial posterior slope in patients undergoing TKA.

Methods

13,586 CT scans of patients undergoing patient specific were analyzed. Three-dimensional reconstructions were performed and the posterior tibial slope was measured. Mean slope and ranges were determined.

Background:

Currently, there are a variety of different reverse shoulder implant designs but few anatomic studies to support the optimal selection of prosthetic size. This study analyzed the glenohumeral relationships of patients who underwent reverse shoulder arthroplasty (RSA).

Methods:

Ninety-two shoulders of patients undergoing primary RSA for a massive rotator cuff tear without bony deformity or deficiency and 10 shoulders of healthy volunteers (controls) were evaluated using three-dimensional CT reconstructions and computer aided design (CAD) software. Anatomic landmarks were used to define scapular and humeral planes in addition to articular centers. After aligning the humeral center of rotation with the glenoid center, multiple glenohumeral relationships were measured and evaluated for linearity and size stratification. The correction required to transform the shoulder from its existing state (CT scan) to a realigned image (CAD model) was compared between the RSA and control groups. Size stratification was verified for statistical significance between groups. Generalized linear modeling was used to investigate if glenoid height, coronal humeral head diameter and gender were predictive of greater tuberosity positions.

Introduction:

Femoro-acetabular impingement reduces the range of motion of the hip joint and is thought to contribute to hip osteoarthritis. Surgical treatments attempt to restore hip motion through resection of bone at the head-neck junction. Due to the broad range of morphologies of FAI, the methodology of osteochondroplasty has been difficult to standardize and often results in unexpected outcomes, ranging from minimal improvement in ROM to excessive head resection with loss of cartilage and even neck fracture. In this study we test whether a standardized surgical plan based on a pre-determined resection path can restore normal anatomy and ROM to the CAM-impinging hip.

Methods:

Computer models of twelve femora with classic signs of cam-type FAI were reconstructed from CT scans. The femoral shaft and neck were defined with longitudinal axes and the femoral head by a sphere of best fit. Boundaries defining the maximum extent of anterior resection were constructed: (i) superiorly and inferiorly along the anterior femoral neck at 12:30 and 5:30 on the clock face, approximating the locations of the vascularized synovial folds; (ii) around the head-neck junction along the edge of the articular cartilage; and (iii) at the base of the neck, perpendicular to the neck axis, 20–30 mm lateral to the articular edge. All four boundaries were used to form 3 alternative resection surfaces that provided resection depths of 2 mm (small), 4 mm (medium), and 6 mm (large) at the location of the cam lesion. Solid models of each femur after virtual osteochondroplasty were created by Boolean subtraction of each of the resection surfaces from the original femoral model. For each depth of neck resection, we measured the following: (i) alpha angle, (ii) anterior offset of the head-neck junction, and (iii) volume of bone removed. Before and after each resection, we also measured the maximum internal rotation of the hip in 90° flexion and 0° abduction.

Introduction:

A disturbing prevalence of painful inflammatory reactions has been reported in metal-on-metal (MoM) hip resurfacing arthroplasty. A contributing factor is localized loading of the acetabular shell leading to “edge wear” which is often seen after precise measurement of the bearing surfaces of retrieved components. Factors contributing to edge wear include adverse cup orientation leading to proximity (<10 mm) of the hip reaction force to the edge of the acetabular component. As this phenomenon is a function of implant positioning and patient posture, this study was performed to investigate the occurrence of edge loading during different functional activities as a function of cup inclination and version.

Methods:

We developed a computer model of the hip joint through reconstruction of CT scans of a proto-typical pelvis and femur and virtually implanting a hip resurfacing prosthesis in an ideal position. Using this model, we examined the relationship between the resultant hip force vector and the edge of the acetabular shell during walking, stair ascent and descent, and getting in and out of a chair. Load data was derived from 5 THR patients implanted with instrumented hip prostheses (Bergmann et al). We calculated the distance from the edge of the shell to the point of intersection of the load vector and the bearing surface for cup orientations ranging from 40 to 70 degrees of inclination, and 0 to 40 degrees of anteversion.

Introduction

Conventional pre-operative planning for total hip arthroplasty mostly relies on the patient radiologic anatomy for the positioning and choice of implants. This kind of planning essentially remains a static approach since dynamic aspects such as the joint kinematics are not taken into account. Hence, clinicians are not able to fully consider the evolving behavior of the prosthetic joint that may lead to implant failures. In fact, kinematics plays an important role since some movement may create conflicts within the prosthetic joint and even provoke dislocations. The goal of our study was to assess the relationship between acetabular implant positioning variations and resultant impingements and loss of joint congruence during daily activities. In order to obtain accurate hip joint kinematics for simulation, we performed an in-vivo study using optical motion capture and magnetic resonance imaging (MRI).

Methods

Motion capture and MRI was carried out on 4 healthy volunteers (mean age, 28 years). Motion from the subjects was acquired during routine (stand-to-sit, lie down) and specific activities (lace the shoes while seated, pick an object on the floor while seated or standing) known to be prone to implant dislocation and impingement. The hip joint kinematics was computed from the recorded markers trajectories using a validated optimized fitting algorithm (accuracy: translational error ≍ 0.5 mm, rotational error < 3°) which accounted for skin motion artifactsand patient-specific anatomical constraints (e.g. bone geometry reconstructed from MRI, hip joint center) (Fig. 1).

3D models of prosthetic hip joints (pelvis, proximal femur, cup, stem, head) were developed based on variations of acetabular cup's inclination (40°, 45°, 60°) and anteversion (0°, 15°, 30°) parameters, resulting in a total of 9 different implant configurations. Femoral anteversion remained fixed and determined as “neutral” with the stem being parallel to the posterior cortex of the femoral neck. Motion capture data of daily tasks were applied to all implant configurations.

While visualizing the prosthetic models in motion, a collision detection algorithm was used to locate abnormal contacts between both bony and prosthetic components (Fig. 2). Moreover, femoral head translations (subluxation) were computed to evaluate the joint congruence.

Introduction

Today, there is no clear consensus as to the amplitude of movement of the “normal hip”. Knowing the necessary joint mobility for everyday life is important to understand different pathologies and to better plan their treatments. Moreover, determining the hip range of motion (ROM) is one of the key points of its clinical examination. Unfortunately this process may lack precision because of movement of other joints around the pelvis. Our goal was to perform a preliminary study based on the coupling of MRI and optical motion capture to define precisely the necessary hip joint mobility for everyday tasks and to assess the accuracy of the hip ROM clinical exam.

Methods

MRI was carried out on 4 healthy volunteers (mean age, 28 years). A morphological analysis was performed to assess any bony abnormalities. Two motion capture sessions were conducted: one aimed at recording routine activities (stand-to-sit, lie down, lace the shoes while seated, pick an object on the floor while seated or standing) known to be painful or prone to implant failures. During the second session, a hip clinical exam was performed successively by 2 orthopedists (2 and 12 years' experience), while the motion of the subjects was simultaneously recorded (Fig.1). These sequences were captured: 1) supine: maximal flexion, maximal IR/ER with hip flexed 90°, maximal abduction; 2) seated: maximal IR/ER with hip and knee flexed 90°. A hand held goniometer was used by clinicians to measure hip angles in those different positions.

Hip joint kinematics was computed from the markers trajectories using a validated optimized fitting algorithm which accounted for skin motion artifacts (accuracy: translational error≍0.5 mm, rotational error <3°). The resulting computed motions were applied to patient-specific hip joint 3D models reconstructed from their MRI data (Fig. 2). Hip angles were determined at each point of the motion thanks to two bone coordinate systems (pelvis and femur). The orthopedist's results were compared.

Introduction:

Adequate coverage of the resected tibial plateau with the tibial tray is necessary to reduce the theoretical risk of tibial subsidence after primary total knee arthroplasty (TKA). Maximizing tibial coverage is balanced against avoiding excessive overhang of the tray causing soft tissue irritation, and establishing proper tray alignment improving implant longevity and patella function¹. Implant design factors, including the number of tray sizes, tray shape, and tray asymmetry influence the ability to cover the tibial plateau². Furthermore, rotating platform (RP) tray designs decouple restoring proper tibial rotation from maximizing tibial coverage, which may enhance the ability to maximize coverage. The purpose of the current study was to assess the ability of five modern tray designs (Fig. 1), including symmetric, asymmetric, fixed-bearing, and RP designs, to maximize coverage of the tibial plateau across a large patient population.

Methods:

Lower limb computed-tomography scans were collected from 14,791 TKA patients and the tibia was segmented. Virtual surgery was performed with an 8-mm tibial resection (referencing the high side) made perpendicular to the tibial mechanical axis in the frontal plane, with 3° posterior slope, and aligned transversely to the medial third of the tibial tubercle. An automated algorithm placed the largest possible tray on the plateau, optimizing the ML and AP placement (and I-E rotation for the RP tray), to minimize overhang. The largest sized tray that fit the plateau with less than 2-mm of tray overhang was identified for each of the five implant systems. The surface area of the tibial tray was divided by the area of the resected plateau and the percentage of patients with greater than 85% plateau coverage was calculated.

INTRODUCTION

A recent PRCT failed to demonstrate superiority of HRA over THA at low speeds. Having seen HRA walk much faster, we wondered if faster walking speed might reveal larger differences.

We therefore asked two simple questions:

Does fast or uphill walking have an effect on the observed difference in gait between limbs implanted with one HRA and one THA?

If there is a difference in gait between HRA and THA implanted legs, which is more normal?

METHODS

Participants All patients who had one HR and one THR on the contralateral side were identified from the surgical logs of two expert surgeons. Both surgeons used a posterior approach to the hip and repaired the external rotators on closure. All consenting patients were assessed using the Oxford Hip Score (OHS) to ensure they had good functioning hips.

There were 3 females and 6 males in the study group, who had a mean age of 67 (55–76) vs the control group 64 (53–82, p = 0.52). The BMIs of the two groups did not differ significantly (28 v 25, p = 0.11).

The mean average oxford score of included patients was 44 (36–48). Radiographs of all subjects were examined to ensure that implanted components were well fixed.

The mean time from THA operation to gait assessment was 4 years (1–17 yrs) and that for HRA was 6 years (0.7–10 yrs, p = 0.31). Subjects in this study had a mean TWS of 6.8 km/hr (5–9.5), and a mean TWI of 19 degrees (10–25 degrees).

Materials and methods

Using a treadmill, instrumented with force plates, we developed a regime of walking at increasing speeds and on varying inclines, both up and down hill. The data from the force plates was then extracted directly, without using the proprietary software that filtered it. Code was written in matlab script to ensure that missed steps were not mistakenly attributed to the wrong leg, automatically downloading of all the gait data at all speeds and inclines.

The pattern of gait of both legs could then be compared over a range of activities.

Results

Wide variation is seen in gait both before and after arthroplasty. The variables that are easiest to explain are these:

width of gait – this appears to be a pre-morbid variable, not easily correctible with surgery. (figure 1)

Downhill gait: as many as 40% of fit patients with ‘well functioning’ total knee replacements choose not to walk downhill at all, while all fit patients with ‘well functioning’ partial replacements are able to do this. Those who can manage, can only manage 90% of the normal speed, unlike unis which are indistinguishable from normal (p < 0.05)

Introduction

Total Knee Replacement (TKR) is a highly effective treatment providing pain relief and improved function to patients experiencing advanced stage osteoarthritis. Tray fit or bone coverage is a critical design feature for both cemented and cementless designs affecting stability, load transfer and potential for infection. Many authors have attempted to characterise the relationship between the profile of the proximal tibia and gender and ethnicity^1–3. As a consequence, a number of manufacturers have commercialised devices designed for specific gender and racial demographics. This study was initiated to compare the effect of the fixed minimum tibial resection depth prescribed by existing surgical instruments with that of a proportionate resection based on the size of the tibia.

Method

A dataset consisting of 30 donor scans from a US cadaver tissue bank (ScienceCare, Memphis, US) was used for this study. The dataset consisted of 12 male and 18 female specimens. Due to the limited view of the diaphysis for most scans, the natural slope of the lateral compartment was used as a guide for orienting the resection. All scans were resected with a 3° posterior slope. For the first part of this study, an equal mediolateral (ML) resection of 9.5 mm, reflecting the minimum resection for the Unity TKR tibia (Corin, UK), was performed on all specimens (Figure 1). Following this, two proportionate resection depths (13.5 mm and 6.7 mm) were calculated based on the ML relationship between the smallest and largest available Unity components (59.5 mm: 84.5 mm). Two further resection depths (11.3 mm and 8.0 mm) were calculated based on a mid size (71.0 mm). Three resection depths (8.0 mm, 9.5 mm & 11.3 mm) were applied to four medium sized specimens. In addition to this two larger specimens were resected at 9.5 mm and 13.5 mm and two smaller specimens at 6.7 mm and 9.5 mm.

A grid was applied to all cut surfaces and oriented using the posterior axis. The cut surface was divided based on lines drawn at 10%, 25%, 50%, 75% and 90% of the overall ML dimension and 10%, 25%, 50%, 75% and 90% of the overall anteroposterior (AP) dimension. Measurements were taken from the medial side and recorded from the points at which lines intersected the external profile of the cut tibia (Figure 2).

Introduction:

Cemented femoral components have been used in hip replacement surgery since its inception. For many patients this works well, but recent retrieval studies^1–4 and more fundamental studies^{5, 6} have highlighted the issues of damage and material loss from the both matt and polished cemented stems.

Materials and methods:

This study will focus on a cohort of retrievals from the Southampton Orthopaedics Centre for Arthroplasty Retrieval Surgery (SOCARS). The cohort consisted of a number of hybrid modular total hip replacements with cemented femoral components, both from mixed and matched manufacturer stem and head combinations. Femoral stems were polished, collarless, tapered designs; head sizes ranged from 28–54 mm. For each femoral stem, samples of Palacos R + G cement (Heraeus Medical GmbH, Hanau, Germany) were retrieved from the proximal region of the cement mantle (Gruen zones 1 and 7), corresponding to both macroscopically damaged and undamaged surfaces of the stem. The areas of damage were determined using calibrated digital photography; damaged surfaces were then imaged in detail using an Alicona InfiniteFocus microscope (Alicona Imaging GmbH, Graz, Austria). The technique uses optical microscopy and focus variation technology to extract 3D morphology and depth information from the surface with a resolution of 10 nm. A series of measurements were made and two different analysis routes were used to provide volumetric material loss measurements from the stem surface. High-resolution microscopy and elemental analysis of the cement and stem surfaces was conducted via SEM and EDX to identify the mechanisms leading to material loss at the cement-stem interface.

Background

There are numerous concerns associated with femoral stems that feature a modular neck design, including the potential for corrosion, modular neck fracture, and adverse local tissue reactions. These stems have a higher-than-anticipated rate of failure in registry results, but large single-center cohort studies are lacking.

Methods

This is a retrospective, single-surgeon cohort of 133 hips in 119 patients implanted with a single dual-tapered titanium alloy stem with a modular titanium alloy neck (Profemur® Z; Wright Medical Technology, Arlington, TN). Several bearing surface combinations were used, including metal-on-polyethylene, ceramic-on-polyethylene, metal-on-metal, and ceramic-on-ceramic couples. Patients were evaluated at a mean of 4.5 years (range 2.0–9.0 years) with Harris Hip scores (HHS), radiographic analysis, and metal ion testing.

Methods:

KneeSIM is a musculoskeletal modeling environment that is built on the foundation of the ADAMS (MSC Software, Santa Ana CA), a rigid body dynamics solver to compute knee kinematics and forces during a deep knee bend. All parameters are customizable and can be altered by the user. Generic three dimensional models of cruciate retaining components of the femoral, tibial, and patellar are available with the software and were used to provide a common reference for the study. The following parameters were modified for each simulation to evaluate the sensitivity of the PCL in the model: 1) Model without PCL, 2) PCL with default properties, 3) PCL Shifted at femoral origin, 7 mm anterior, 7 mm inferior; tibial origin maintained; 4) PCL with increased stiffness properties (2x default), 5) position in the femur and tibia remained default position and 6) PCL with default properties and location, joint line shifted 4 mm superior. The standard output of tracking the flexion facet center (FFC) motion of the medial and lateral condyles was utilized (Figure 1).

Results:

Figure 2 and 3 displays the output of the six conditions tested above. Comparing the curves for the medial and lateral motion show different patterns with the lateral point having more posterior translation than the medial. After approximately 95° of flexion, all cases exhibit an anterior translation in the model. This motion was consistent for all test cases. The model showed no difference with motion either with or without the PCL and with changing the stiffness. Altering the location of the PCL on the femoral insertion had the greatest effect on motion, while shifting the joint line superior was second. The shift of the ligament insertion and changing of the joint line results in the ligament being more parallel to the tibial surface which provides resistance to anterior motion or posterior translation.

Introduction:

Kinematic studies are used to evaluate function and efficacy of various implant designs. Given the large variation between subjects, matched pairs are ideal when comparing competing designs. It is logical to deduce that both limbs in a subject will behave identically during a given motion [1], barring unilateral underlying pathology, thus allowing for the most direct comparison of two designs. It is our goal to determine if this is a valid assumption by assessing whether or not there are significant differences present in the kinematics of left and right knees from the same subject. Gait studies have compared pre-and postoperative implantation kinematics for various pathologies like ACL rupture [2] and osteoarthritis [3, 4]. We designed a study to assess squatting in cadaver specimens.

Methods:

Sixteen matched pairs of fresh-frozen cadavers, (Eleven males, five females; aged 71 years [± 10 yrs]) were tested. Each knee, intact, was tested by mounting it on a dynamic, quadriceps-driven, closed-kinetic-chain Oxford knee rig (OKR), which simulated a deep knee bend from full extension to 120° flexion. We chose femoral rollback, tibiofemoral external rotation, tibial adduction, patellofemoral tilt and shift as our outcomes, which were recorded using an active infrared tracking system.

Introduction:

Despite over 95% long-term survivorship of TKA, 14–39% of patients express dissatisfaction due to anterior knee pain, mid-flexion instability, reduction in range of flexion, and incomplete return of function. Changing demographics with higher expectations are leading to renewed interest in patient-specific designs with the goal of restoring of normal kinematics.

Improved imaging and image-processing technology coupled with rapid prototyping allow manufacturing of patient-specific cutting guides with individualized femoral and tibial components with articulating surfaces that maximize bony coverage and more closely approximate the natural anatomy. We hypothesized that restoring the articular surface and maintaining medial and lateral condylar offset of the implanted knee to that of the joint before implantation would restore normal knee kinematics. To test this hypothesis we recorded kinematics of patient-specific prostheses implanted using patient-specific cutting guides.

Methods:

Preoperative CT scans were obtained from nine matched pairs of human cadaveric knees. One of each pair was randomly assigned to one of two groups: one group implanted with a standard off-the-shelf posterior cruciate-retaining design using standard cutting guides based on intramedullary alignment; the contralateral knee implanted with patient-specific implants using patient-specific cutting guides, both manufactured from the preoperative CT scans. Each knee was tested preoperatively as an intact, normal knee, by mounting the knee on a dynamic, quadriceps-driven, closed-kinetic-chain Oxford knee rig (OKR), simulating a deep knee bend from 0° to 120° flexion. Following implantation with either the standard or patient-specific implant, knees were mounted on the OKR and retested. Femoral rollback, tibiofemoral rotation, tibial adduction, patellofemoral tilt and shift were recorded using an active infrared tracking system.

Introduction

Tibial components that match the resected proximal tibia may promote accurate rotational alignment and maximize coverage while minimizing overhang in total knee arthroplasty (TKA). Tibial component designs have traditionally been evaluated utilizing an overall anterior-posterior (AP)/medial-lateral (ML) ratio. However, since the tibial plateau is irregularly shaped, such a metric has drawbacks. Here, a detailed set of morphological metrics is used to evaluate six contemporary tibia designs against a multi-ethnic bone database.

Methods

Tibial surfaces from 347 subjects, including 97 Indian (50m/47f), 99 Japanese (44m/55f), and 151 Caucasian (85m/66f), were virtually resected following a specific TKA procedure, as previous publications have shown surgical variability minimally impacts tibial resection morphology. Medial and lateral AP dimensions (MAP and LAP), ML width (ML), and medial and lateral anterior radii (MAR and LAR) were measured in a coordinate system constructed on the resected surface based on the neutral rotational axis (Fig. 1A). These metrics, along with anterior radius asymmetry (MAR/LAR), were regressed against ML for each ethnicity. The regressions were then compared with similar measurements obtained from tibial components in six contemporary TKA systems (one asymmetric: Design A; four symmetric: Designs B-E; and one anatomic: Design F).

Introduction:

Non-hinged constrained condylar components (CCK) may be used for primary TKA in presence of severe deformity, fixed contractures and ligamentous laxity. Several authors have recommended use of stem extensions to accompany CCK type of components. However, use of stem extensions in primary TKA, not only invades the medullary canal, but may also be associated with increased surgical time, implant cost, and thigh or leg pain. The purpose of this study was to assess the short-term outcomes of primary CCK knees without stem extensions and to compare this to a control group of standard posterior stabilized (PS) knees, otherwise using the same implant design.

Materials and Methods:

We retrospectively reviewed the clinical and radiographic data on 503 consecutive TKA's performed by 2 arthroplasty surgeons at the same institution between 2008–2010. Surgical technique, implant type, bone-cement and cementation technique was similar. The only difference between groups was the use of CCK polyethylene insert in one group and a PS insert in the other. Knee society scores (KSS) were used to determine pain, function and ROM. Radiographic evaluation was done using the knee society's criteria to determine implant fixation. Failure was defined as revision for any reason. Statistical analyses were performed using SPSS software.

Background:

A large percentage of the patients who present for unilateral TKA have bilateral disease. Performing simultaneous, bilateral TKA has been debated and currently there is no consensus on the risks and benefit of this approach. In addition, specific selection criteria have not been defined to more accurately identify which patients are potentially appropriate candidates for this approach.

Objectives:

The purpose of this study was to evaluate the clinical outcomes and peri-operative complications in simultaneous, bilateral TKA's using pre-operative patient selection criteria.

INTRODUCTION:

The diagnosis of periprosthetic joint infection (PJI) remains a serious challenge. Based on previous work, we believe that biomarkers will become the mainstay of diagnosing PJI in the future. We report on completion of our 8 year comprehensive biomarker program, evaluating the diagnostic profile of the 15 most promising synovial fluid biomarkers.

METHODS:

Synovial fluid was prospectively collected from 99 patients being evaluated for infection in the setting of revision hip or knee arthroplasty. All synovial fluid samples were tested by immunoassay for 15 putative biomarkers that were developed and optimized specifically for use in synovial fluid. Sensitivity, specificity and receiver operating Characteristic (ROC) curve analysis were performed for all biomarkers.

Methods:

A total of 6 specimens were used to perform this in vitro cadaver test using extensometers to provide numerical values for laxity and varus-valgus tilting in the frontal plane. See Fig. 1 The test set-up.

Findings:

This study enabled a very precise measurement of varus and valgus laxity as compared with the clinical assessment which is a subjective measure. The strains in both ligaments in the replaced knee were different from those in the native knee. Both ligaments were stretched in extension, in flexion the MCL tends to relax and the LCL remains tight. Fig. 2 Initial and maximal strain values in the MCL during valgus and varus laxity testing in different flexion angles. a: intact knee, b: replaced knee. and Fig. 3 Initial and maximal strain values in the LCL during valgus and varus laxity testing indifferent flexion angles. a: intact knee, b: replaced knee.

Introduction

The purpose of this study was to determine the efficacy of a multi-modal blood conservation protocol that involved pre–operative autologous blood donations (2 units) in conjunction with erythropoietin supplementation as well as intra-operative conservation modalities.

Methods

A retrospective chart review of 90 patients with simultaneous bilateral total knee arthroplasty done between 2006–2009 by one of the 3 senior authors was performed. Patients donated two units of blood 4 weeks prior to surgery and also received erythropoietin injections (40,000 units: 3 weeks, 2 weeks and 1 week prior to surgery). Intra- operative blood management included use of pneumatic tourniquet, re-infusion drains, local epinephrine injections and fibrin spray. Post-operatively, autologous transfusions were provided based on symptoms. Pre-donation blood levels, peri-operative hemoglobin and hematocrit levels along with transfusion records were assessed.

Background:

Total hip arthroplasty (THA) has been proven to be successful in achieving adequate pain relief and favorable outcomes in patients suffering from hip osteoarthritis (OA). However, leg length discrepancy (LLD) is still a significant cause of morbidities such as nerve damage, low back pain and abnormal gait. Despite most of the reported values of LLD in the literature being within the acceptable threshold of < 10 mm, some patients still report dissatisfaction, leading to litigation against orthopedic surgeons. However, lower extremity lengthening is sometimes necessary to achieve adequate hip joint stability and prevent dislocations. The purpose of this study was to compare LLD in patients undergoing THA using three different techniques: conventional anterior-approach THA (ATHA), conventional posterior-approach THA (PTHA), and robotic-assisted posterior-approach THA (RTHA) using the MAKO™ robotic hip system.

Materials and Methods:

All cases of RTHA, ATHA and PTHA that were performed by the senior surgeon between Sep 2008 and Dec 2012 were reviewed. Patients included in this study had a primary diagnosis of hip osteoarthritis, with available and proper post-operative antero-posterior pelvis radiographs. All radiographs were calibrated and measurements done twice by two blinded observers.

Introduction:

Acetabular revision Jumbo cups are used in revision hip surgeries to allow for large bone to implant contact and stability. However, jumbo cups may also result in hip center elevation and instability. They may also protrude through anterior wall leading to ilopsoas tendinitis.

Methods:

The study was conducted using two methods:

Computer simulation study

265 pelvic CT scans consisting of 158 males and 107 females were converted to virtual 3-dimensional bones. The average native acetabular diameter was 52.0 mm, SD = 4.0 mm (males in 52.4 mm, SD = 2.8 mm and 46.4 mm, SD = 2.6 mm in females). Images were analyzed by custom CT analytical software (SOMA™ V.3.2)¹ and over-sized reaming was simulated. Four distinct points, located in and around the acetabular margins, were used to determine the reamer sphere. Points 1, 2, 3 were located at the inferior and inferior-medial acetabular margins, and Point 4 was located superiorly and posteriorly in the acetabulum to simulate a bony defect in this location, Point 4 was placed at 10%, 20%, 30%, 40%, 50% and 60% of the distance from the superior – posterior margin of the acetabular rim to the sciatic notch to simulate bony defects of increasing size. (Figure 1)

Radiographical study

Retrospective chart review of patient records for all cementless acetabular revisions utilizing jumbo cups between January 1, 1998 and March 30, 2012 at UCFS (98 patients with 57 men, 41 women). Jumbo cups: ≥66 mm in males; <62 mm in females. Reaming was directed inferiorly to the level of the obturator foramen to place the inferior edge of the jumbo cup at the inferior acetabulum. To determine the vertical position of the hip center, a circle was first made around both the jumbo and the contralateral acetabular surfaces using Phillips iSite PACS software. The center of this circle was assumed to correspond to the “hip center”. The height of the hip center was estimated by measuring the height of a perpendicular line arising from the interteardrop line (TL) and ending at the hip center

Background:

Complications following hip and knee arthroplasty can occur in any given patient. However, specific risk factors such as increased age, history of coexistent disease, and increased body mass index have been found to increase the risk of complications after such procedures. Complications often require prolonged hospital admission periods and added hospital resources which ultimately results in increased costs per hospital stay. However, if patients are pre-operatively risk stratified, and followed post-operatively for specific high risk medical issues, many complications may be avoided. By using a hospital standardised peri-operative risk stratification process, the cost per hospital stay for hip and knee arthroplasty may decrease.

Hypothesis:

Overall hospital costs related to joint arthroplasty will be decreased by using a multi-disciplinary peri-operative risk stratification programme.

Introduction:

The higher resisting torque against dislocation and the large range of motion due to the enlarged effective head diameter substantiate the use of eccentric dual-mobility cups in case of total hip joint instability [1,2]. As a result of force-dependent self-centering mechanism, an increased movement of the intermediate-component can be expected whose effect on wear propagation is unknown so far. Currently available hip joint simulators are only able to vary the load by the absolute value and not by the direction of resulting force. Therefore, the uniaxial force transmission may lead to a unique and stable alignment of the intermediate-component during testing. The purpose of this numerical study was to evaluate relative movements of the intermediate-component during daily life activities with respect to wear propagation.

Method:

The numerical analysis was based on a standard dual-mobility system consisting of a polished metallic cup, a UHMWPE intermediate-component (40 mm outer diameter) with an eccentric offset of 2 mm and a 28 mm ceramic femoral head [Fig. 1]. The relative motion of the intermediate-component was affected by the geometrically generated self-centering torque (T_C) and the friction torque for inner (T_Fi) and outer (T_Fo) articulation around the centre of rotation Z₁[Fig. 2]. In order to consider lubrication conditions the lambda ratio was estimated for different daily life activities [3], including the calculation of composite roughness and minimum film thickness for a ball-on-plate configuration. The friction torque was related to the product of load (F_Res), lever arm and the coefficients of friction which were determined using the equation proposed by [4]. Depending on load F_Res and load orientation angle βthe equilibrium of moments around Z₁ was established.

Introduction:

The prevalence of total hip (THA) and knee arthroplasty (TKA) is growing dramatically, with more than 1 million procedures performed annually in the United States. As the cost of and demand for the newest orthopaedic implants continue to rise, the price paid to medical device companies for implants is a growing concern. Some high-volume healthcare institutions have adopted price capitation strategies to control costs, in which a flat purchase price is negotiated for all implant line items regardless of technology and material. The purpose of this study was to evaluate whether the implementation of price capitation in a large health system affected trends in THA and TKA premium implant selection by surgeons. A secondary objective was to compare selection trends between surgeons with an academic center affiliation and community practice surgeons, within a single health system.

Methods:

All consecutive primary THA and TKA cases six months before (1/1/2011–6/30/2011) and after (8/1/2011–1/31/2012) implementation of a capitated pricing strategy (7/1/2011) were identified. Surgeon education regarding the new pricing policy was conducted for 1-month following implementation, and data during this time were omitted from the study. After exclusions (Figure 1), a total of 481 THA and 674 TKA from the large hospital, and 253 THA and 315 TKA from the two community hospitals comprised the final study cohort. A retrospective review of patient demographics and implant characteristics for each case was performed. Premium THA implants were defined by the existence of one of the following bearing surfaces: second (2G) or third generation (3G) highly cross-linked polyethylene liner with a ceramic or oxidized-zirconium femoral head, ceramic liner with a ceramic femoral head, or mobile-bearing system. Premium TKA implants were defined by the existence of at least one of the following criterion: mobile-bearing design, high-flexion design, oxidized-zirconium femoral component, and/or highly cross-linked polyethylene bearing surface. Pearson's chi-square analyses and Fisher's exact test were used to compare implant usage between pre- and post-capitated pricing time periods.

Introduction:

There is substantial range in kinematics and joint loading in the total knee arthroplasty (TKA) patient population. Prospective TKA designs should be evaluated across the spectrum of loading conditions observed in vivo. Recent research has implanted telemetric tibial trays into TKA patients and measured loads at the tibiofemoral (TF) joint [1]. However, the number of patients for which telemetric data is available is limited and restricts the variability in loading conditions to a small subset of those which may be encountered in vivo. However, there is a substantial amount of fluoroscopic data available from numerous TKA patients and component designs [2]. The purpose of this study was to develop computational simulations which incorporate population-based variability in loading conditions derived from in vivo fluoroscopy, for eventual use in computational as well as experimental activity models.

Methods:

Fluoroscopic kinematic data was obtained during squat for several patients with fixed bearing and rotating platform (RP) components. Anterior-posterior (A-P) and internal-external (I-E) motions of the TF joint were extracted from full extension to maximum flexion. Joint compressive loading was estimated using an inverse-dynamics approach. Previously-developed computational models of the knee, lower limb, and Kansas knee simulator were virtually implanted with the same design as the fluoroscopy patients. A control system was integrated with the computational models such that external loading at the hip and ankle were determined in order to reproduce the measured in vivo motions and compressive load (Fig. 1). Accuracy of the model in matching the in vivo motions was assessed, in addition to the resulting joint A-P and I-E loading.

The external loading determined for a broader range of patients can subsequently be utilized in a force-controlled simulation to assess the robustness of implant concepts to patient loading variability. The applicability of this work as a comparative tool was illustrated by assessing the kinematics of two PS RP designs under three patient-specific loading conditions.

Introduction:

Primary stability is crucial for long-term fixation of cementless tibial trays. Micromotion less than 50 μm is associated with stable bone ingrowth and greater than 150 μm causes the formation of fibrous tissue around the implant [1, 2]. Finite element (FE) analysis of complete activities of daily living (ADL's) have been used to assess primary stability, but these are computationally expensive. There is an increasing need to account for both patient and surgical variability when assessing the performance of total joint replacement. As a consequence, an implant should be evaluated over a spectrum of load cases. An alternative approach to running multiple FE models, is to perform a series of analyses and train a surrogate model which can then be used to predict micromotion in a fraction of the time. Surrogate models have been used to predict single metrics, such as peak micromotion. The aim of this work is to train a surrogate model capable of predicting micromotion over the entire bone-implant interface.

Methods:

A FE model of an implanted proximal tibia was analysed [3] (Fig. 1). A statistical model of knee kinetics, incorporating subject-specific variability in all 6-DOF joint loads [4], was used to randomly generate loading profiles for 50 gait cycles. A Latin Hypercube (LH) sampling method was applied to sample 6-DOF loads of the new population throughout the gait cycle. Kinetic data was sampled at 10, 50 and 100 instances and FE predictions of micromotion were calculated and used to train a surrogate model capable of describing micromotion over the entire bone-implant interface. The surrogate model was tested for an unseen gait cycle and the resulting micromotions were compared with FE predictions.

INTRODUCTION

Modular metal-on-metal hip implants show increased revision rates due to fretting and corrosion at the interface. High frictional torque potentially causes such effects at the head-taper interface, especially for large hip bearings. The aim of this study was to investigate fretting and corrosion of sleeved ceramic heads for large ceramic-on-ceramic (CoC) bearings.

METHODS

The investigated system consists of a ceramic head (ISO 6474-2; BIOLOX® Option), a metal sleeve (Ti-6Al-4V, ISO 5832-3) and different metal stem tapers (Ti-6Al-4V, ISO 5832-3; stainless steel, ISO 5832-1; CoCrMo, ISO 5832-12). Three different test methods were used to assess corrosion behaviour and connection strength of head-sleeve-taper interfaces: –

Fretting corrosion acc. to ASTM F1- Corrosion under in-vivo relevant loads

Standardized fretting corrosion tests were carried out. Additionally, a long term test (0.5 mio. cycles) under same conditions was performed.

Corrosion effects under 4.5 kN (stair climbing) and 10 kN (stumbling) were determined for three groups. One group was fatigue tested applying 4.5 mio. cycles at 4.5 kN and 0.5 mio. cycles at 10 kN in a corrosive fluid. In parallel two control groups (heads only assembled at same load levels) were stored in the same fluid for same time period. Pull-off tests were performed to detect the effect of corrosion on the interface strength.

A new designed test was performed to analyse the connection strength and fretting-corrosion effects on the head-sleeve taper interfaces caused by frictional torque of large CoC bearings (48 mm). Two separate loading conditions were investigated in a hip joint simulator. One created bending torque (pure abduction/adduction), the other set-up applied rotational torque (pure flexion). A static axial force of 3 kN and movements with a frequency of 1 Hz up to 5 mio. cycles in the same corrosive fluid as in the second set of tests were applied for both tests. Surface analysis of the taper and sleeve surfaces was peformed. In order to detect loosening caused by frictional torque, torque-out tests were conducted after simulator testing.

Introduction:

Reverse shoulder arthroplasty (RSA) has proven to be a useful tool to manage a variety of pathologic conditions. However, inconsistent improvement in motion occurs in patients who have undergone RSA for revision shoulder arthroplasty, proximal humeral fracture sequelae, and treatment of infection. Additional factors that have been suggested to produce poor postoperative range of motion (ROM) may be associated with patient's factors such as poor preoperative range of motion and surgical factors such as inability to lengthen the arm. The purpose of this study was to analyze multiple factors which may be responsible in predicting motion after RSA. It is our hypothesis that intraoperative ROM is most predictive of postoperative ROM.

Methods:

Between February 2003 and April 2011 566 patients (225 male and 341 female) treated with a RSA for 1) acute proximal humeral fracture (11), 2) Sequeala of proximal humeral fractures (31), 3) cuff tear arthropathy (278), 4) massive cuff tear without arthritis (78), 5) failed shoulder arthroplasty (168) and 6) infection (29) were evaluated with preoperative range of motion, intraoperative range of motion and range of motion at a minimum of 2-year postoperative follow up. A single observer recorded intraoperative flexion (IFF) in 30° increments. Preoperative and postoperative ROM was recorded by patient video or a previously validated patient performed outcome measure. Preoperative diagnosis was confirmed by radiographic and intraoperative information. 477 patients had preoperative and postoperative radiographs available for analysis of acromial-greater tuberosity distance change (AGT) which was utilized to calculate arm lengthening. A regression analysis was then performed to determine which factors were most influential in predicting postoperative active range of motion.

Purpose:

Starting February 2012, our institution changed from enoxaparin (Lovenox) to the Factor Xa inhibitor, rivaroxaban (Xarelto) for venous thromboembolism prophylaxis after primary total hip (THA) and total knee arthroplasty (TKA). The purpose of our study was to compare rates of venous thromboembolism and rates of major bleeding between these two medications when used for venous thromboembolism prophylaxis after primary THA and TKA.

Methods:

A retrospective review was performed on 1795 patients who underwent THA or TKA at our institution between January 1, 2011 and December 31, 2012. Patients were excluded if they had a bilateral procedure, partial arthroplasty (hip hemiarthroplasty, unicompartmental knee arthroplasty), revision surgery, and cases designated as complex. Patients were excluded if they were on other anticoagulants (dabigatran, aspirin, clopidogrel, warfarin, heparin, fondaparinux), or if pre-operative creatinine was 1.2 or greater. After excluding these patients, there were 1089 patients included in the study. Chart review recorded demographics (age, gender), comorbidities (BMI, ASA, creatinine), surgery performed (primary THA or TKA), length of stay (LOS), venous thromboembolic events (deep venous thrombosis [DVT], pulmonary embolus [PE]), post-operative infections, and major bleeding events (stroke, post-operative bleeding requiring transfusion). Periprosthetic infection rates are also currently being reviewed. T-tests were used to compare continuous variables between treatment groups, and Chi-square tests were used to compare categorical variables between treatment groups (α = 0.05).

Objective:

Evaluation of the early results of the implementation of reverse shoulder arthroplasty prosthesis “Comprehensive Reverse” in primary and revision shoulder arthroplasties.

Material and Methods:

September 2010–December 2012, 48 patients (32 women, 16 men) underwent reverse shoulder arthroplasty using Comprehensive Reverse system. Average age of 69.88. A total of 46 patients were followed. In 22 patients the operation was performed for revision. Patients were pre-and postoperatively evaluated using Oxford, Constant, SF-12 scores, radiographs, pain and range of motion. Mean follow-up 13 months.

Introduction

Total knee arthroplasty (TKA) prostheses are semi-constrained artificial joints. A well-functioning TKA prosthesis should be designed with a good balance between stability and mobility, meaning the femorotibial constraint of the artificial joint should be appropriate for the device's function. To assess the constraint behavior of a TKA prosthesis, physical testing is typically required, and an industrial testing standard has been developed for this purpose [1]. Computer simulation has become increasingly useful in many industries, including medical device research and development where finite element analysis (FEA) has been extensively used in stress analysis and structural evaluation. This study presents an FEA-based simulation to evaluate the femorotibial constraint behavior of TKA prosthesis, and demonstrated the effectiveness of the method by validating through physical testing.

Methods

A Cruciate Retaining (CR) TKA prosthesis design (Optetrak Logic CR, Exactech, USA) was used in this study. CAD models of the implants assembled at 0° of flexion were used for the simulation. Finite element models were generated using with all materials assumed linear elastic. Boundary conditions were set up according to the ASTM F1223 standard (Figure 1). The tibial baseplate was fixed distally. A constant compressive force (710 N) was applied on the femoral component. Nonlinear Surface-Surface-Contact was defined at the femorotibial articulating surfaces. Coefficient of friction was determined from physical test. The femoral component was driven under a displacement-controlled scheme to slide along the anterior-posterior (AP) direction on the tibial insert. At each time step, constraint force occurring at the articulating surface was derived from the reaction force at the distal fixation of the tibial baseplate. A nonlinear FEA solver (NX Nastran SOL601, Siemens, USA) was used to solve the simulation. In addition, five samples of the prostheses were physically tested, and the results were compared with the simulation.

Introduction:

Unicompartmental knee arthroplasty (UKA) has been proven to be an effective treatment for degenerative joint disease confined to a single tibiofemoral compartment. Recently, UKAs have been performed with robotic-arm assistance (RAA) devices to build and improve upon previous computer-assisted navigation. As a pilot study, we have analyzed short term outcomes for a series of robotic-arm assisted medial UKAs and compared them to a comparable cohort of traditionally instrumented medial UKAs.

Methods:

Ninety-eight fixed-bearing medial UKAs were isolated in our prospective data collection database for short-term analysis for this study. Included patients completed pre and post-operative Short Form 12 version 1 Health Survey (SF12), Western Ontario and McMaster University Outcome Scores (WOMAC), and Knee Society Function Score (KSFS) questionnaires. Forty-eight RAA UKAs were performed using the MAKO RIO system with Restoris implants, and fifty manual UKAs were performed with the Zimmer® Unicompartmental High-Flex Knee System (ZUK).

Introduction:

Total hip arthroplasty (THA) is extremely effective in treating debilitating arthritic conditions of the hip. With the many modular prosthetic designs available, surgeons can now precisely construct mechanical parameters such as femoral offset (FO). Although several studies have investigated relationships between offset choice and hip abductor strength, hip range of motion, and prosthetic wear rate, there is scarce data on the effect of FO on pain and functional outcomes following THA. The objective of this study was to assess the effect of restoring FO (within varying degrees compared to the contralateral non-diseased hip [CL]) on physical function, mental well-being, pain, and stiffness outcomes as measured by the Short Form 12 Health Survey (SF-12) and Western Ontario and McMaster University Osteoarthritis Index (WOMAC) at post-operative follow-up.

Methods:

We prospectively collected data on 249 patients that underwent unilateral THA with no or minimal disease of the contralateral hip. Baseline data collection included: age, gender, diagnosis, femoral head size, type of stem, and pre-operative SF-12 and WOMAC scores. Post-operative SF-12 and WOMAC scores were recorded during annual follow-up visits. Post-operative FO was retrospectively measured on standard anteroposterior (AP) pelvis radiographs and compared to FO of CL. FO was measured as the perpendicular distance from the femoral head center of rotation to the anatomic axis of the femur with appropriate adjustments made for image magnification. Patients were categorized into one of three groups: decreased femoral offset (dFO, less than −5 mm compared to CL), normal femoral offset (nFO, between −5 and +5 mm of CL), and increased femoral offset (iFO, greater than +5 mm compared to CL).

Introduction:

For 30 years, uncemented anatomic hip stems have been implanted with documented clinical results[1,2]. Their geometry can be linked back to the geometry of the PCA and ABG stems. Modifications to date include stem length, body geometry, material, and reduction in distal geometry. New tools have been developed allowing anatomical measurements and analysis of three-dimensional digital femora geometry through CT scans[3]. The purpose of this study is to analyze three-dimensional contact of various anatomic hip stem designs using this technique.

Methods:

Six femora (57–87 yrs, 72–88 kg), were selected from a CT scan database (SOMA™) of 604 Caucasian bones. They were selected based on femoral anteversion (average +/−1.5 * std. dev.) with three measuring[4] 8–10° and three 31–33° of anteversion. The CT scans were segmented into cancellous/cortical bone and converted into CAD models in PRO/Engineer Wildfire (v.5). A/P views of the bones were scaled to a 120% magnification to allow three surgeons to surgically template and choose the stem size and location (maximizing fill (n = 1); restoring the head center (n = 2)) with two implant designs (1-Citation TMZF and 2-ABG II Monolithic, Stryker Orthopaedics, Mahwah). Measurements from templating were used to virtually implant CAD models of the implants into the bones (n = 36 bone/stem assemblies). The assemblies were imported into Geomagic Qualify 2012 for 3D deviation analysis comparing the coated region of the implant to the cortical-cancellous boundary. The analysis generated color map profiles based on the following categories: Contact (−2.0 to 0.5 mm), Conformity (0.5 to 2.0 mm), Proximity (2.0 to 5.0 mm), and Gap (5.0 to 12 mm) and the percent of the surface that was within each of these categories. These results were compared for patterns within and across the anatomic families.

Introduction:

Two fixed bearing options exist for tibial resurfacing when performing unicompartmental knee arthroplasty (UKA). Inlay components are polyethylene-only implants inserted into a carved pocket on the tibial surface, relying upon the subchondral bone to support the implant. Onlay components have a metal base plate and are placed on top of a flat tibial cut, supported by a rim of cortical bone. To our knowledge, there is no published report that compares the clinical outcomes of these two implants using a robotically controlled surgical technique. We performed a retrospective review of a single surgeon's experience with Inlay versus Onlay components, using a robotic-guided protocol.

Methods:

All surgeries were performed using the same planning software and robotic guidance for execution of the surgical plan (Mako Surgical, Fort Lauderdale, FL). The senior surgeon's prospective database was reviewed to identify patients with 1) medial-sided UKA and 2) at least two years of clinical follow up. Eighty-six patients met these inclusion/exclusion criteria: 41 Inlays and 45 Onlays. Five patients underwent a secondary or revision procedure during the follow up period and were considered separately. Our primary outcome was the WOMAC score, subcategorized by the Pain, Stiffness, and Function sub-scores. The secondary outcome was need for secondary surgery. Continuous variables were analyzed using the two-tailed Student's t-test; categorical variables were analyzed using Fisher's exact test.

Introduction:

Patient specific instrumentation (PSI) generates customized guides from a magnetic resonance imaging based preoperative plan for use in total knee arthroplasty (TKA). PSI software must be able to accommodate differences in implant design. The purpose of the present study was to determine whether any differences in the accuracy of limb alignment, component alignment, component sizing, or bony resection could be identified in patients undergoing PSI TKA with identical PSI software and one of two different implant systems.

Methods:

In this case-control study, two different implant systems from the same manufacturer were evaluated in 37 consecutive PSI TKA (Group 1) and 123 consecutive PSI TKA (Group 2) performed by a single surgeon. A third group (Group 3) consisted of 12 consecutive TKA performed with manual instrumentation and the same implant system as Group 1. Identical software was used to generate a preoperative plan from which planned limb alignment, component alignment, component sizes, and bony resection were determined. Intraoperatively, actual component sizes, bony resection, and recut frequency were determined. Long-standing and lateral radiographs were obtained preoperatively and 4-weeks postoperatively to evaluate limb and component alignment.

Introduction

Infection following total knee arthroplasty (TKA) is a catastrophic complication. In the United States, for chronic, first time infected TKA, the gold standard remains a 2-stage reimplantation (2SR) procedure, with reported success rates approaching 90%. However, there is a lack of consensus on the treatment of subsequent reinfections.

Question

The purpose of this study was to use published data on infected TKA to develop a decision tree analysis to determine the treatment method likely to yield the highest quality of life for a patient following a failed 2SR.

Background:

Metal-on-metal total hip arthroplasty (THA) implants have been widely debated due to the adverse wear issue related to the bearing surfacing. However, more recent studies have shown that the high metal ion problems that occur after surgery with this type of implant may not be exclusively related to the all metal bearing surfaces, but mainly due to the recently modified connecting tapers. Biomet is one of few companies who have not changed their original taper design for their THA implants. The purpose of this study was to present our up to eight-year clinical results.

Method:

Between November 2004 and April 2011, all of the 196 cases in 167 patients (77 male vs. 89 female) performed by a single surgeon were included in this study. The Biomet Magnum/Jumbo metal-on-metal total hip arthroplasty implants were utilized for all of the cases. The average age was 59 ± 11 years at the time of surgery. Thirteen patients deceased from causes unrelated to THA. The primary diagnosis was OA in 124 cases; followed by AVN in 41 cases, dysplasia in 12 cases and other causes in the remaining 19 cases. The average acetabular component sizes were 54 ± 4 mm. Clinical and radiographic examinations were performed prospectively, and the results were analyzed.

Introduction

Proper soft-tissue balance is important for achieving favorable clinical outcomes following TKA, as ligament imbalance can lead to pain, stiffness or instability, accelerated polyethylene wear, and premature failure of implants. Until recently, soft-tissue balancing was accomplished by subjective surgeon feel and by use of static spacer blocks. Now, nanonsensor-embedded implant trials allow surgeons to quantify peak load and center of load in the medial and lateral compartments during the procedure, and to adjust ligament tension and implant positioning accordingly. The purpose of this 3-year, multicenter study is to evaluate 500 patients who have received primary TKA with the use of intraoperative sensors in order to correlate quantified ligament balance to clinical outcomes.

Methods

To date, 7 centers have contributed 215 patients who have undergone primary TKA with the use of intraoperative sensors. Patients are seen at a pre-operative visit (within 3 months prior to surgery), and post-operatively at 6 weeks, 6 months, and at 1, 2, and 3-year anniversaries. Standard demographic and surgical data is collected for each patient, including: age at time of surgery, BMI, operative side, gender, race, and primary diagnosis. At each interval, anatomic alignment and range of motion are assessed; KSS and WOMAC evaluations are administered; and a set of standard radiographs is collected, including: standing anteroposterior, standing-lateral, and the sunrise patellar view. Intraoperative loads were recorded for pre- and post-release joint states. All soft-tissue release techniques were recorded. “Optimal” soft-tissue balance was defined as a medial-lateral load difference of less than or equal to 15 lbs.

Introduction:

Dual mobility total hip arthroplasty (DM-THA) allows for very large femoral head size, which may be beneficial for hip range of motion (ROM). No clinical study has objectively compared ROM in patients with DM-THA and large (36-mm head) total hip arthroplasty (36-THA). The aim of this prospective case-control study is to test the hypotheses that DM-THA provides superior hip ROM compared to 36-THA by dynamic radiography, and that surgical approach (posterolateral [PL] versus modified anterolateral [AL]) has effect on post-operative hip ROM.

Materials and Methods:

Sixteen patients (11 males, 5 females) who had undergone DM-THA with a minimum follow up of one year were age, sex and body mass index (BMI) matched to twenty patients (12 males, 8 females) with 36-THA, all operated upon by the senior author. Maximum hip-trunk flexion, extension and total hip-trunk ROM was calculated on standing lateral digital radiographs of the lower lumbar spine, pelvis and hip, using commercially available software (TraumaCad®, BrainLab, Munich, Germany) from three upright positions; standing neutral, standing with maximum hip flexion and standing with maximum hip extension. Contributions to motion from lumbo-sacral spine (LSS) and pelvic tilt were calculated and subtracted from hip-trunk measurements to quantify true hip flexion, extension and total true hip ROM. Statistical analysis (SPSS software, Chicago, IL) was performed on all radiographic measurements to detect difference in ROM between DM-THA and 36-THA, and to detect difference in ROM between THAs performed through posterolateral (THA-PL) and anterolateral (THA-AL) approaches.

Introduction

Rehabilitation after shoulder arthroplasty is a fundamental in enabling patients achieve a good functional outcome. Therapists must consider the underlying diagnosis, operative technique employed and rotator cuff integrity, amongst other factors, in order to select the most appropriate exercise regime. There is an absence of comprehensive studies in the literature with regard to shoulder rotational exercises. Therefore, this study aimed to describe the shoulder girdle muscle activation strategies during eight commonly cited rotational shoulder exercises.

Method

Thirty healthy subjects with no history of shoulder problems participated in the study. EMG was recorded from 16 shoulder girdle muscles (surface electrodes: anterior, middle and posterior deltoid, upper, middle and lower trapezius, upper and lower latissimus dorsi, upper and lower pectoralis major; fine wire electrodes: supraspinatus, infraspinatus, subscapularis and rhomboid major) using a telemetry based EMG system. Five external and three internal rotation exercises were included (table 1). Signal acquisition and processing were in accordance with standardised guidelines. Amplitude normalisation was to external and internal rotation maximum voluntary contraction as appropriate. Mean EMG amplitudes between exercises were compared using repeated measures ANOVA. Data for muscle groups was calculated by averaging the activation of the component muscles.

Introduction:

Given that factors like center of rotation (COR), neck shaft angle, glenosphere diameter and component tilt alter the biomechanics of reverse total shoulder arthroplasty (rTSA), the performance of the total rTSA system is of interest. This study compared the composite performance of two rTSA systems that were designed around a medialized or lateralized glenohumeral COR. The objective was to quantify the following outcome measures: 1) COR & humeral position; 2) range of glenohumeral abduction; 3) force to abduct; and 4) range of internal (IR)/external (ER) rotation.

Methods:

Seven pairs of shoulders were tested with a biomechanical shoulder simulator. Beads were implanted in the scapula and humerus to quantify bone positions with a fluoroscope. Spectra lines simulated the deltoid and the rotator cuff. Linear actuators simulated muscle excursion while load cells recorded applied force. Diode arrays were used to quantify arm position and calculate the humeral center of rotation. Native specimens were tested where a motion path was recorded from resting to peak glenohumeral abduction in the scapular plane. The trajectory was replayed and deltoid force vs. arm position was recorded. With the elbow flexed, the arm was articulated to maximal internal and external rotation to determine ROM limits due to impingement or soft tissue constraint. Specimens were implanted with a Tornier Aequalis Reversed Shoulder prosthesis (“A,” 36 mm glenosphere, 10° humeral retroversion, 9 mm poly insert – “medial”) or a DJO Surgical Reverse Shoulder Prosthesis (“R,” 32 mm, 30° retroversion, neutral insert/shell – “lateral”). Implants were randomized between shoulders in a pair. After implantation the test protocol was repeated. Paired-t tests (p ≤ 0.050) were adjusted with Holm's step-down correction for multiple comparisons.

Introduction:

Revision total knee arthroplasty (TKA) can be very complex in nature with difficulties/obstacles involving bone and soft tissue deficits, visualization and exposure, as well as alignment and fixation. Auxiliary devices such as augmentation and offset adapters help address these issues; however they increase the complexity of the reconstruction. The objective of this study was to show that use of a single radius revision TKA system allowing for minimal auxiliary revision devices can yield positive early clinical outcomes.

Methods:

This data was collected as part of a prospective, post-market, multicenter study. One hundred and twenty-five single radius revision TKA cases were evaluated. Surgical details were reviewed and cases were grouped based on type of auxiliary devices used. Group 1 included cases that used only femoral and/or tibial augments. Group 2 used femoral and/or tibial augments in conjunction with femoral and/or tibial offset adapters. Early clinical outcomes, operative data and radiographic findings were used to compare cases.

Introduction:

Total shoulder arthroplasty (TSA) is the current standard treatment for severe osteoarthritis of the glenohumeral joint [1]. Often, severe arthritis is associated with abnormal glenoid version or excessive posterior wear [2]. Reaming to correct more than 15° of retroversion back to neutral is not ideal as it may remove an excessive amount of the outer cortical support and medialize the glenoid component [3]. Two recent glenoid components with posterior augments—wedged and stepped—have been designed to address excessive posterior wear and to allow glenoid component neutralization. Hypothetically, these augmented glenoid designs lessen the complications associated with using a standard glenoid component in cases of shoulder osteoarthritis with excessive posterior wear. We set out to determine which implant type (standard, stepped, or wedged) corrects retroversion while removing the least amount of bone in glenoids with posterior erosion.

Methods:

Serial shoulder CT scans were obtained from 121 patients before total shoulder arthroplasty. These were then classified using the Walch Classification. We produced 3D models of the scapula from CT scans for 10 subjects that were classified as B2 using the software MIMICS (Materialise, Belgium). Each of these 10 glenoid subjects were then virtually implanted with standard, stepped, and wedged glenoid components (Fig 1). The volume of surgical bone removed and maximum reaming depth were calculated for each design and for each subject. In addition, the area of the backside of the glenoid in contact with cancellous versus cortical bone was calculated for each glenoid design and for each subject (Fig 2). ANOVA testing was performed.

Introduction

It has been suggested that corrosion and fretting at the taper junctions of stemmed metal-on-metal hip replacements may contribute to their high failure rates. A peer-reviewed semi-quantitative scoring system [Goldberg et al., 2002] has been used to visually assess the severity of corrosion and fretting of the taper junction but has not been validated using multiple examiners. The aim of this study was to assess the inter-observer variability of this method.

Method

Macroscopic and stereomicroscopic examinations of the femoral head and stem tapers of 100 retrieved large diameter metal on metal (MOM) hip components were performed by two independent observers using the methods defined by Goldberg et al. [2002] to quantify corrosion and fretting. Scores ranging from 1 (none) to 4 (severe) were assigned to the medial, lateral, posterior and anterior quadrants of the neck taper and the distal and proximal regions of the head taper. An overall score was then assigned to each surface as a whole.

Cohen's weighted Kappa statistic (κ) was used to measure the inter-observer agreement. A quadratic weighting scheme, that allocated weights to the importance of disagreements that are proportional to the square of the number of categories apart, was used to take account of scaled disagreement.

Kappa values were assessed using previously established criteria where κ ≤ 0 = poor, 0.01 to 0.20 = slight, 0.21 to 0.40 = fair, 0.41 to 0.60 = moderate, 0.61 to 0.80 = substantial, 0.81 to 1 = almost perfect.

A sample size of 100 was used in order to detect a coefficient of 0.60 to within 0.25 with 95% confidence with two experienced observers. Statistical analysis was performed using Stata/IC version 12.1 (StataCorp, College Station, TC, USA) and a p value < 0.05 was considered statistically significant.

Introduction

Metal-on-metal (MOM) total hip arthroplasty using large diameter femoral heads offer clinical advantages however the failure rates of these hips is unacceptably high. Retrieved hips have a wide range of wear rates of their bearing and taper surfaces and there is no agreement regarding the cause of failure.

Detailed visual inspection is the first step in the forensic examination of failed hip components and may help explain the mechanisms of failure. The aim of this study was to determine if there was a correlation between the results of detailed inspections and the volumetric wear of the bearing and taper surfaces of retrieved hips.

Method

Detailed, non-destructive macroscopic and stereomicroscopic examinations of 89 retrieved MOM hip components were performed by a single experienced examiner using quantitative assessment to document the severity of 10 established damage features:

Light scratches, Moderate scratches, Heavy scratches, Embedded particles, Discolouration, Haziness, Pitting, Visible wear zone, Corrosion, Fretting

Each surface was considered in terms of zones comprising of quadrants (cup, head, and taper) and subquadrants (cup and head), Figure 1. Each zone was scored on a scale of 0 to 3 by determining the percentage of the surface area of the zone that exhibited the feature in question: a score of 0=0%, 1<25%, 25%<2<75%, 3>75%. The sum of the scores of each zone was used for the assessment of each damage feature.

The volume of wear at the surfaces of each hip was measured with a Zeiss Prismo coordinate measuring machine (cup and head) and a Talyrond 365 roundness measurement instrument (taper), using previously reported methods^{1, 2}.

Simple linear regression models were used to asses the univariable associations between the inspection scores and wear volumes. Multiple linear regression models were subsequently used to asses the simultaneous contribution of the inspection scores, found significant in univariable analyses, on the wear outcome variables.

All statistical analysis was performed using Stata/IC version 12.1 (StataCorp, USA) and throughout a p value < 0.05 was considered statistically significant.

Introduction

We have been developed lateral flare stem and have been using it since 1989. It was custom stem at first. After being experienced, using the same software, off-the-shelf version lateral flare stem (Revelation) was developed in 1996 in the U.S. We could start using it since 2001 in our country. Lateral flare stems are designed to reproduce physiological proximal load transfer lateral side as well as medial side. It was obtained by having bigger and more accurate proximal part with lateral flare. The design is optimized by matching with 3D insertion path.

Using many custom stems including different length and off-the-shelf standard stems, we have come to feel that as for this high proximal fit and load transfer design, it is not necessary to having long distal part and sometimes it is harmful to obtain good proximal load transfer in some situation such as type A (champagne flute) canal. So we have developed short version of the stem. Many makes of the hip stems have included short stems recently. Some aimed to improve easier insertion, some aimed to improve the volume of residual bone quantity. We have aimed to improve proximal fit expecting more proximal and more physiological load transfer to the femur.

Objectives

Our objectives are to comare standard stem and short stem from biomechanical aspect and clinical aspect.

Introduction

Massive defect of the acetabular bone is one of the severe situation in the hip arthroplasty. Installation of cup supporter or acetabular reinforcement device is one of the important method as well as big cup and bone graft etc. Preparing the device to be suitable shape is very important and installing it at the very position where the shaping was intended is also very important to obtain a stable condition for the arthroplasty. When we use navigation system, the device must be programmed in. But it is impossible to programme a device we have bended by ourselves into the system. If we can use a navigation system for such devices for those cases, we can expect better installation. We can fit the device on the patient's bone during the surgery of course; which is the ordinary procedure fot it; but it requires much time and tissue damage maybe with less accurate fitting.

Materials and Methods

Two primary and three revision total hip arthroplasty cases with severe acetabular bone defect were treated with this method. First we have made chemical wood model for each case and bended the cup supporter on it. (Fig. 1) Then CAT scan of the model and the bended device on it were taken. Then the coordinate system of DICOM data set of the patient's original pelvis and the second DICOM data set i.e. the bended prosthesis were unified using MIMICS (Materialize, Belgium.) An STL format geometry data file of the bended device was extracted and merged into original DICOM dataset. Thus we could obtain a DICOM data set we call “predicted post-op DICOM.” During the surgery, a navigation system was used based on the predicted DICOM data.

Introduction

Malpositioning of the tibial component is a common error in TKR. In theory, placement of the tibial tray could be improved by optimization of its design to more closely match anatomic features of the proximal tibia with the motion axis of the knee joint. However, the inherent variability of tibial anatomy and the size increments required for a non-custom implant system may lead to minimal benefit, despite the increased cost and size of inventory.

This study was undertaken to test the hypotheses: 1.

That correct placement of the tibial component is influenced by the design of the implant.

Materials and Methods

CAD models were generated of all sizes of 7 widely used designs of tibial trays, including symmetric (4) and asymmetric (3) designs. Solid models of 10 tibias were selected from a large anatomic collection and verified to ensure that they encompassed the anatomic range of shapes and sizes of Caucasian tibias. Each computer model was resected perpendicular to the canal axis with a posterior slope of 5 degrees at a depth of 5 mm distal to the medial plateau. Fifteen joint surgeons and fourteen experienced trainees individually determined the ideal size and placement of each tray on each resected tibia, corresponding to a total of 2030 implantations. For each implantation we calculated: (i) the rotational alignment of the tray; (ii) its coverage of the resected bony surface, and (iii) the extent of any overhang of the tray beyond the cortical boundary. Differences in the parameters defining the implantations of the surgeons and trainees were evaluated statistically.

Introduction:

Despite all the attention to new technologies and sophisticated implant designs, imperfect surgical technique remains a obstacle to improving the results of total knee replacement (TKR). On the tibial side, common errors which are known to contribute to post-operative instability and reduced function include internal rotation of the tibial tray, inadequate posterior slope, and excessive component varus or valgus. However, the prevalence of each error in surgeries performed by surgeons and trainees is unknown. The following study was undertaken to determine which of these errors occurs most frequently in trainees acquiring the surgical skills to perform TKR.

Materials and Methods:

A total of 43 knee replacement procedures were performed by 11 surgical trainees (surgical students, residents and fellows) in a computerized training center. After initial instruction, each trainee performed a series of four TKR procedures in cadavers (n = 2) and bone replicas (n = 2) using a contemporary TKR instrument set and the assistance of an experienced surgical instructor. Prior to each procedure, computer models of each cadaver and/or bone replica tibia were prepared by reconstructing CT scans of each specimen. All training procedures were performed in a navigated operating room using a 12 camera motion analysis system (Motion Analysis Inc.) with a spatial resolution in all three orthogonal directions of ± 0.15 mm.

The natural slope, varus/valgus alignment, and axial rotation of the proximal tibial surface were recorded prior to surgery and after placement of the tibial component. For evaluation of all data, acceptable limits for implantation were defined as: posterior slope: 0–10°; varus/valgus inclination of tibial resection: ± 3°; and external rotation: 0–10°.

Introduction:

Patient-specific cutting guides (PSCG) built from imaging of the extremity can improve the accuracy of bone cuts during total knee replacement (TKR). Some reports have suggested that PSCG offer only marginal improvement in the accuracy of alignment and component positioning in TKA. We compared outcomes between TKRs done with PSCG versus standard, intramedullary-based instrumentation.

Methods:

Blood loss, duration of surgery, alignment of the mechanical axis of the leg, and implant position on standing, long-leg, and standard lateral digital radiographs were compared between a CT-guided, custom-built TKA implant (n = 50; ConforMIS iTotal, Boston, MA) implanted with PSCG, versus an off-shelf posterior stabilized TKA implanted with standard instrumentation (n = 50; NKII total knee, Zimmer, Warsaw, IN). The fraction of outliers (>3 degrees) was calculated for the two groups.

Introduction

The utilization of sonicate fluid cultures (SFC) has been shown to increase the detection rate of periprosthetic joint infection (PJI) in comparison to the use of conventional microbiological methods, because sonication enables a sampling of the causative bacteria directly from the surface of the endoprosthetic components. The hypothesis of this study is that not only will the detection rate of PJI be improved, but also the detection rate of polymicrobial infection in patients with total knee arthroplasty (TKA) revision surgery.

Material and methods

74 patients which underwent TKA revision surgery received a synovial aspiration, intraoperative tissue cultures, histological sampling of the periprosthetic membrane, and sonication of the explanted endoprosthesis. A PJI was defined according to the following criteria: presence of intraarticular pus or a sinus tract, positive isolation of causative bacteria in ≥2 microbiological samples or a histological membrane indicative of infection (type II or III periprosthetic membrane).

Introduction

Sonicate fluid cultures (SFC) are more sensitive than conventional microbiological methods in identifying periprosthetic joint infections (PJI), because sonication enables a sampling of the causative bacteria directly from the surface of the endoprosthetic components. Because of their high sensitivity SFC can be positive while all other microbiological methods remain negative. It is therefore difficult to interpret a single SFC as being truly or falsely positive. The aim of this prospective study was to improve the interpretation of SFC in the diagnosis of PJI in patients after total hip arthroplasty through the use of multiple SFC.

Material and methods

102 patients of which 37 had a defined PJI according to the following criteria were included: intraarticular pus or a sinus tract, a periprosthetic membrane (PM) indicative of infection, or a positive microbiological culture in a minimum of 2 separate microbiological samples. A single positive microbiological sample was classified as false positive. In 35 patients multiple SFC were acquired from the separate endoprosthetic components.

Introduction:

Varus alignment of the knee is common in patients undergoing unicondylar knee replacement. To measure the geometry and morphology of these knees is to know whether a single unicondylar knee implant design is suitable for all patients, i.e. for patients with varus deformity and those without. The aim of this study was to identify any significant differences between normal and varus knees that may influence unicondylar implant design for the latter group.

Methodology:

56 patients (31 varus, 25 normal) were evaluated through CT imaging. Images were segmented to create 3D models and aligned to a tri-spherical plane (centres of spheres fitted to the femoral head and the medial and lateral flexion facets). 30 key co-ordinates were recorded per specimen to define the important axes, angles and shapes (e.g. spheres to define flexion and extension facet surfaces) that describe the femoral condylar geometry using in-house software. The points were then projected in sagittal, coronal and transverse planes. Standardised distance and angular measurements were then carried out between the points and the differences between the morphology of normal and varus knee summarised. For the varus knee group, trends were investigated that could be related to the magnitude of varus deformity.

Introduction

Wear debris induced osteolysis and loosening continue to be causes of clinical failure in total knee replacement (TKR). Laboratory simulation aims to predict the wear of TKR bearings under specific loading and motion conditions. However, the conditions applied may have significant influence on the study outcomes (1)

The aim of this study was to examine the influence of femoral setup and kinematic inputs on the wear of a conventional polyethylene fixed bearing TKR through experimental and computational models.

Methods

Six right Sigma CR fixed bearing TKRs (DePuy Synthes, Leeds, UK) with curved polyethylene inserts (GVF, GUR1020 UHMWPE) were tested in Prosim knee simulator (Simulator Solutions, UK). The femoral bearing was set up with the centre of rotation (CoR) on either on the distal radius of the implant (Distal CoR), as indicated by the device design, or according to the ISO specification (ISO CoR; ISO14243-3). The tests were conducted under ‘High Kinematics’ (2). It was necessary to reverse the direction of the anterior-posterior displacement for the tests conducted with the ISO centre of rotation to maintain the contact region within the insert surface (Reverse High Kinematics). Tests were conducted for three million cycles, lubricated with 25% bovine serum, with wear assessed gravimetrically.

The computational wear model for the TKR was based on the contact area and an independent experimentally determined non-dimensional wear coefficient, previously validated against the experimental data (3).

Introduction

There has been renewed interest in the use of unicompartmental knee arthroplasty (UKA) for patients with limited degenerative disease of the knee due to improved surgical techniques and prosthetic design, and the desire for minimally invasive surgery. However, patient satisfaction following UKA for lateral compartment disease have been suboptimal with increased revision rates. Robotic-assisted UKA has been shown to improve precision and accuracy of component placement, which may improve outcomes of lateral UKA. The purpose of this study was to compare the outcome of robotic-assisted UKA to conventional UKA for degenerative disease of the lateral compartment with the hypothesis that robotic-assisted lateral UKA results in superior outcomes compared to conventional UKA.

Methods

The institution's joint registry was searched for patients who underwent UKA for limited degenerative disease of the lateral knee compartment between 2004 and 2012 and a total of 125 lateral UKAs were identified. The medical records of all patients were reviewed and assessed for the type of surgical procedure used (robotic-assisted versus conventional), length of hospital stay, Oxford knee score, and occurrence of revision surgery. Preoperative and postoperative radiographs were assessed for tibiofemoral angle, femoral and tibial joint line angle, posterior tibial slope, and orientation of the femoral and tibial components.

Introduction:

A pulmonary embolus (PE) occurs frequently in medical patients and acutely in post surgical total joint patients. While the two groups seem vastly different, there has never been an analysis of the location, number of emboli a patient has and size of the emboli in post-operative total joint arthroplasty patients compared to general medical patients. Studies have looked at the size of PEs relative to symptomatic patients; recent data have suggested the timeline of PE development is usually within the first few days after total knee arthroplasty (TKA) or total hip arthroplasty (THA).

Methods:

We conducted a retrospective chart review at Providence Hospital from 2006 to 2011 of all THA and TKA patients who had a post-operative PE diagnosis and looked at their medical comorbidities, sex, age, procedure, post-operative day of PE, and size/location of PE using a novel pulmonary mapping tree database based on location of the PE on spiral computed tomography (CT). The same data, except for post-operative day, was collected for the medical population with a PE diagnosis. Size was defined based on level of blockage with small emboli occurring at different points within a lobe, medium being at the level of lobe, and large being either a saddle embolus or at the right or left pulmonary artery. Inclusion criteria for orthopaedic patients included THA or TKA performed prior to PE, PE within 1 month of surgery and CT confirming diagnosis of a PE. Medical patients meeting criteria had to have an admitting diagnosis of PE with CT confirmation of the PE. Exclusion criteria included V/Q scan alone to diagnose the PE.

Background:

Glenoid component loosening remains as an unsolved clinical problem in total shoulder arthroplasty. Current clinical assessment relies on subjective quantification using a two-dimensional plane X-ray image with arbitrarily defined criteria. There is a need to develop a readily usable clinical tool to accurately and reliably quantify the glenoid component motion over time after surgery. A high-resolution clinical CT has the potential to quantify the glenoid motion, but is challenged by metal artifact from the prosthetic humeral components. The objective of this study is to demonstrate the feasibility of using a clinical CT reconstruction to quantify the glenoid implant motion with the aid of tantalum markers.

Methods:

Three spherical tantalum markers of 1.0 mm in diameter were inserted into three peripheral pegs of an all polyethylene glenoid component. The glenoid component was implanted in a sawbone scapula. To determine the effect of metal artifact on quantification of glenoid implant motion, two sawbone humerii were used: one without the prosthetic humeral components and the other with the prosthetic humeral head and stem. Three custom-made translucent spacers with the uniform thickness were placed between the glenoid component and the scapula to produce a gradual translation of the glenoid component from 1 mm to 3 mm. Before and after inserting each spacer, the surface of the glenoid component was digitized by a MicroScribe. The surface points were used to fit a sphere and the corresponding center of the sphere was calculated. The actual translation of the glenoid component was measured as the three-dimensional (3D) distance between the center of the sphere before and after insertion of each spacer. Then, the shoulder model was scanned by a clinical CT with and without the spacers for both humerii conditions. Velcro straps were used to secure the humerus to the glenoid component between the trials. All CT scans were reconstructed in VolNinja software to superimpose the scapula positions (Figure 1). The three tantalum markers were visualized and the center coordinates of the markers were used to measure the 3D distance before and after insertion of each spacer. The accuracy was defined by the difference between the averaged 3D distance measured by CT reconstruction and that measured by the MicroScribe. The standard deviation of the 3D distance measured by each tantalum marker was calculated to evaluate the reliability of the tantalum marker visualization.

Introduction

From a tribological point of view and clinical experience, a ceramic-on-ceramic bearing represents the best treatment option after rare cases of ceramic component fracture in total hip arthroplasty (THA). Fractured ceramic components potentially leave small ceramic fragments in the joint capsule which might become embedded in PE acetabular liners.

Purpose

This in vitro study compared for the first time the wear behaviour of femoral ball heads made of ceramic and metal tested with PE liners in the presence of ceramic third-body debris.

The contamination of the test environment with third-body ceramic debris, insertion of ceramic fragments into the PE liners and implementation of continuous subluxation simulated a worst-case scenario after revision of a fractured ceramic component.

Introduction:

Total knee arthroplasty (TKA) should aim to adjust the component gap (CG) difference between extension and flexion. However, this difference cannot be measured without placement of a femoral component. The bone gap reportedly decreases in extension after component setting. In contrast, it may be possible to use the mean value of the CG difference in several patients to adjust femoral resection amount beforehand. The purpose of this study is to evaluate the technique of adjusting CG difference using the mean values with measured resection technique (MRT) in TKA.

Materials and methods:

The subjects were 222 knees (40 male knees, 182 female knees; mean age 70.4 years). To adjust the CG difference after estimation, the femoral posterior condylar pre-cut technique was used. Extension gap was created by usual bone resection; 4 mm of the femoral posterior condyle was pre-cut, and after all osteophytes and soft tissues had been treated, a pre-cut trial component (thickness of 8 mm for distal femur and 4 mm for posterior condyle without the anterior portion) was mounted, achieving the same condition as the setting of a femoral component in MRT (Fig. 1). When the posterior cruciate ligament (PCL) could be easily preserved by intraoperative gap assessments, the PCL was preserved (190 knees, 86%).

Questions/purposes:

What factors influence tibial tray-cement interface bond strength? We developed a laboratory model to investigate this issue with the goal of providing technical recommendations to mitigate the risk of tibial tray-cement loosening.

Methods:

Forty-eight size 4 Triathlon® tibial trays were cemented into an acrylic holder using two different cements: Simplex® and Palacos®; three different cementing times: early (low viscosity), per manufacturer (normal, medium viscosity), and late (high viscosity); two different cementation techniques: cementing tibial plateau only and cementing tibial plateau and keel; and two different fat (marrow) contamination conditions: metal/cement interface and cement/cement interface. A push-out test was applied at a velocity of 0.05 mm/s, and the load recorded continuously throughout the test at a rate of 10 Hz. The test was stopped when the plate debonded from the cement (i.e. the tray visibly separated from the acrylic support and the load dropped substantially). Statistical analysis was performed using Welch's t-tests and Cohen's d tests.

[Introduction]

One of the modern design total knee arthroplasty (TKA) system, the NexGen Legacy posterior-stabilized (LPS) Flex prosthesis, has been in use at our hospital since 2001. Between 2006 and 2011, NexGen LPS-Flex primary TKA were mainly performed in combination with a cemented short-keeled minimally invasive version tibial tray (MIS tibial component) instead of the traditional NexGen stemmed tibial tray. We observed some cases required early revision of isolated tibial component in primary TKA performed in this period. Therefore, our objectives were to report the series of this revision cases and to consider this failure mechanism.

[Patients & Methods]

A total of 526 primary TKAs were performed using a NexGen LPS-Flex prosthesis and MIS tibial component during five-year period at our hospital. The mean age was 74 years at the time of the index procedure. We assessed revision rate of this tibial tray in this study and described clinical course of the revision cases. We also examined the clinical and radiographic features which could be associated with the failure.

INTRODUCTION:

One common surgical treatment of even early OA is the implantation of a Total Joint Arthroplasty. In case of younger patients this procedure is questionable. The present study investigates the behaviour of a new silk derived scaffold supplied by Orthox Ltd. (Abingdon, UK) in an in vivo sheep model. This scaffold allows replacing the damaged areas with a resurfacing technique and will avoid the implantation of a total joint in cases of early OA.

METHODS:

The scaffolds where derived from silk fibres by processing into a composite of an open porous matrix in combination with a fibres mash with the same material and covered with a smooth surface. During the process the fluid silk can be casted in any shape. Eight sheep (4 ± 1 years) underwent a surgery where a large defect (2×1 cm) was created in the weight bearing zone of the medial condylus followed by implantation of a scaffold. The unoperated contra lateral stifle joint served as control.

After six months the animals were sacrificed and the joints inspected for inflammation. The Young's modulus of the cartilage and scaffold was determined by indentation or confined compression tests. All tissues were fixed in formaldehyde for histology. The data were analysed by a Wilcoxon and Mann-Whitney-U-test. The roughness of the smooth surface was measured. Synovial fluid was harvested by punction before opening the joint and analysed for particle wear debris and for any signs of inflammation.

Introduction

Limb alignment after unicondylar knee arthroplasty (UKA) has a significant impact on surgical outcomes. The literature lacks studies that evaluate the limb alignment after lateral UKA or compare alignment outcomes between medial and lateral UKA. In this study, we retrospectively compare a single surgeon's alignment outcomes between medial and lateral UKA using a robotic-guided protocol.

Methods

All surgeries were performed by a single surgeon using the same planning software and robotic guidance for execution of the surgical plan. The senior surgeon's prospective database was reviewed to identify patients who had 1) undergone medial or lateral UKA for unicompartmental osteoarthritis; and 2) had adequate pre- and post-operative full-length standing radiographs. There were 229 medial UKAs and 37 lateral UKAs in this study. Mechanical limb alignment was measured in standing long limb radiographs both pre- and post-operatively. Intra-operatively, limb alignment was measured using the computer assisted navigation system. The primary outcome was over-correction of the mechanical alignment (i.e, past neutral). Our secondary outcome was the difference between the radiographic post-operative alignment and the intra-operative “virtual” alignment as measured by the computer navigation system. This allowed an assessment of the accuracy of our navigation system for predicting post-operative limb alignment after UKA.

Purpose

The purpose of this study is to evaluate the midterm results of cementless revision total hip arthroplasty (THA) using Wagner Cone Prosthesis.

Material and Methods

Between 1996 and 2007, 36 hips in 36 consecutive patients underwent femoral revision THA using Wagner Cone Prosthesis. Among them 28 hips were followed for more than 5 years. The mean age at revision surgery was 57 years and a mean follow-up was 7.6 years. The Paprosky classification system was used for preoperative bone loss evaluation. Clinical results were evaluated using Harris hip scores. For evaluation of the femoral component, radiolucent lines at bone-implant interfaces were evaluated and femoral component vertical subsidence was measured. Heterotopic bone formation and complications were also evaluated.

Background:

The use of reverse total shoulder arthroplasty (RTSA) has been increasing around the world. However, because of concerns over lack of internal rotation with the reverse prosthesis and the resultant difficulties with activities of daily living (ADLs), many have recommended against performing bilateral RTSA.

Methods:

We performed a retrospective review of prospectively obtained clinical data on 15 consecutive patients (30 shoulders) that underwent staged bilateral primary RTSA for the diagnosis of cuff tear arthropathy (CTA) between 2004 and 2012. All operations were performed by a single surgeon. The mean follow-up was 29.6 months from the second RTSA (range 12–65 months). The mean age of the patients at the time of the first operation was 72.9 years (range 63–79 years), and the mean duration between arthroplasties was 21.6 months (range 8–50 months). Patients were evaluated preoperatively and postoperatively at 2 weeks, 6 weeks, 3 months, 6 months, 1 year, and yearly with standardized clinical exams and outcome measures questionnaires including Constant, ASES, UCLA, Simple Shoulder Test, SPADI, and SF-12 scores.

Introduction:

Over the last several decades, life expectancy following solid organ transplant (i.e. kidney, liver, heart, lung, and pancreas) has increased significantly, largely due to improvements in surgical technique, immunosuppressive regimens, patient selection, and postoperative care. As this population ages, many of these transplant patients become candidates for total knee arthroplasty (TKA). However, these patients may be at greater risk of complications following TKA due to immunosuppression and metabolic derangements secondary to organ dysfunction. The purpose of this study was to use a large, nationally representative database to compare morbidity, mortality, length of stay (LOS), and charges for TKA patients with and without a history of solid organ transplant.

Methods:

This retrospective study was a review of the Nationwide Inpatient Sample (NIS; the largest all-payer inpatient care United States database representing a 20% stratified sample) from 1998 to 2010. Patients who had a primary TKA (ICD-9-CM 81.54) were included (n = 5,706,675, weighted national frequency). A total of 763,924 cases were excluded for the following: age <18 years, pathologic fracture of lower extremity, malignant neoplasm and/or metastatic cancer, previous and/or bilateral arthroplasty, admission type other than “elective”. The remaining 4,942,751 patients were categorized as transplant (n = 5,245; included only liver, kidney, heart, lung and/or pancreas transplant) or non-transplant group (n = 4,931,017; no history of any transplant including solid organ or tissue). A multivariable regression model was used to identify any association(s) between a history of solid organ transplant and morbidity, mortality, LOS and hospital charges, while adjusting for patient and hospital characteristics.

Background

Discrepancies in patient outcomes after total knee arthroplasty have encouraged the development of different treatment options including early preventive interventions. In addition, improvements in surgical techniques and instrumentation have increased the accuracy of the surgeries. In this case study, we review the first robotic-arm assisted modular tricompartmental knee arthroplasty in which bone and soft tissues are conserved by employing a precise planning and execution technique.

Materials and Methods

A 63 year old Caucasian female with a Body Mass Index (BMI) of 27 presented to the surgeon (SK) with knee pain and a varus mechanical alignment. The patient received modular tri-unicompartmental arthroplasty performed with robotic-arm assistance; (see figure 1 for post-op radiograph). Range of Motion (ROM), Knee Society Score (KSS) and Knee Injury and Osteoarthritis Outcomes Score (KOOS) were measured pre-operatively and post-operatively at 6, 16, and 23 months. At 6 months post-op an in-depth in vivo kinematic analysis was conducted by using a validated fluoroscopic assessment technique [1]. The patient simulated stair climbing, kneeling activity, and deep lunge while under single plane fluoroscopy. Three dimensional models were created from CT scans and were matched to 2D fluoroscopic images for kinematic assessment.

INTRODUCTION:

Proximally coated femoral stems have been designed to address the shortcomings of fully coated femoral stems including proximal femoral stress shielding. The design improvements leading to more optimized proximal femoral loading condition in the “Neck preserving stems” have increased the popularity of such implants (e.g., Minihip). Neck preserving stems depict better biological outcomes compared to more traditional stems ¹ by utilizing more natural mechanical stress/strain distribution over the femur. These stems provide significant reduction in both torsional and bending moments at the stem/bone interface. This reduction may result in decreasing the micromotion and failure of osseointegration ¹. Figure 1 demonstrates the differences between the cutting areas of a neck preserving versus traditional stem. The Minihip stem demonstrate a curved structure that is designed to match the shape of the femoral neck. The stability of the implant is achieved in the femoral neck and intertrochanteric area of the proximal femur. Further investigations are needed to establish a solid ground for the outcome of these stem in total hip arthroplasty (THA).

OBJECTIVES:

The current study was conducted to report the short-term clinical outcome of the THA by using Minihip neck preserving stem.

Introduction:

Unicompartmental knee arthroplasty (UKA) has been used in the past decades to treat progressive cartilage degeneration in a single compartment. Concern has been raised over the rate of revision procedures for polyethylene wear and osteoarthritic progression into the adjacent compartment. Few studies have examined the pathology of cartilage degeneration in the setting of UKA. This study aims to investigate the viability of knee chondrocytes introduced to high and low concentrations of orthopaedic wear debris particulate.

Methods:

Normal human articular chondrocytes (nHAC-Kn) were expanded in DMEM/F12 containing 10% FBS, 1% Penicillin/Streptomycin (Pen/Strp), and 50 μg/mL ascorbic acid (Asc). 24 hours prior to the start of the experiment, cells were seeded on 96-well plates at a density of 3500 cells/cm² and exposed to DMEM/F12 containing 5% FBS, 1% Pen/Strp, and 50 μg/mL Asc. Particles (equivalent circle diameter range: 0.2–7 μm) at a low dose of 100: 1 (particles: cells) and high dose 1000: 1 (particles: cells) were introduced to treatment wells (n = 6). Control wells (n = 6) contained particles with no cells.

Treatment groups included high and low doses of TiAl₆V₄ alloy, 316L Stainless Steel, and Co-Cr-Mo alloy. At days 1, 3, 5, and 7, cells were assayed with a 3-(4,5-Dimethylthiazol-2-yl)-2,5-dyphenyltetrazolium bromide (MTT) assay for determination of cell viability. Light microscopy was performed at each timepoint to assess change in cell morphology.

Background:

Previous studies regarding modular head-neck taper corrosion were largely based on cobalt chrome (CoCr) alloy femoral heads. Less is known about head-neck taper corrosion with ceramic femoral heads.

Questions/purposes:

We asked (1) whether ceramic heads resulted in less taper corrosion than CoCr heads; (2) what device and patient factors influence taper fretting corrosion; and (3) whether the mechanism of taper fretting corrosion in ceramic heads differs from that in CoCr heads.

INTRODUCTION:

Recent trends in total hip arthroplasty (THA) have resulted in the use of larger acetabular components to achieve larger femoral head sizes to reduce dislocation, and improve range of motion and stability. Such practices can result in significant acetabular bone loss at the time of index THA, increasing risk of anterior/posterior wall compromise, reducing component coverage, component fixation, ingrowth surface and bone stock for future revision surgery. We report here on the effects of increasing acetabular reaming on component coverage and bone loss in a radiographic CT scan based computer model system.

METHODS:

A total of 74 normal cadaveric pelves with nonarthritic hip joints underwent thin slice CT scan followed by upload of these scans into the FDA approved radiographic analysis software. Utilizing this software package, baseline three-dimensional calculations of femoral head size and acetabular size were obtained. The software was used to produce a CT scan based model that would simulate reaming and placement of acetabular components in these pelves that were 125, 133 and 150% the size of the native femoral head. Calculations were made of cross sectional area bone loss from anterior/posterior columns, and loss of component coverage with increasing size.

Introduction

Medial unicompartmental knee arthroplasty (UKA) for isolated medial knee arthritis is a highly successful and efficacious procedure. However, UKA is technically more challenging than total knee arthroplasty (TKA). Research has shown that surgical technical errors may lead to high early failure rates. Haptic robotic systems have recently been developed with the goal of improving accuracy, reducing complications, and improving overall outcomes. There is little research comparing robotic-assisted UKA to standard UKA. The goal of this study was to compare clinical and radiographic data for matched cohorts who received robotic-arm assisted UKA or standard instrumentation UKA.

Methods

We performed a non-randomized, retrospective review of 30 robotic-arm assisted UKA and 32 manual UKA performed by single fellowship-trained joint arthroplasty surgeon (SKK) over 2.5 years. All procedures completed through a medial parapatellar approach. All components were cemented. All tibial components were a metal-backed onlay design. Average follow-up was 10.1 months (range 5–36). A full clinical/hospital chart review of demographic, intra- and post-operative measures was performed. Radiographic analysis of pre- and post-op images evaluating sagital and coronal alignment, and component positioning was performed by single observer (DCH), using OsiriX imaging system (Pixmeo; Geneva, Switzerland). Radiographs were available for analysis in 28 robotic-assisted and 30 manual patients. Statistical analysis was performed using SPSS v. 20. Comparison between group means was performed as well as calculation of variance in component placement within groups.

Background

Antibiotic-loaded cement has been used over decades as a local antibiotic delivery for the treatment of bone and joint infections. However, there were some disadvantages such as unpredictable elution, insufficient local concentration and reduced mechanical strength. We developed hydrophilized bone cement and investigated whether it can improve consistent antibiotic release for extended periods to be effective in eradicating joint infection without any changes of mechanical strength.

Methods

The experiments consists of preparation of the hydrophilized, vancomycin-loaded bone cement, In vitro test including drug release behavior, mechanical properties by compression test, cytotoxicity, antibacterial effect and animal study. In animal study, Antibiotic cement rod was implanted in the femur of rat osteomyelitis model. Sign of infections were assessed by gross observation, Micro CT and blood analysis at indicated period.

Introduction:

This study evaluates the impact of radii-related differences in posterior cruciate ligament retaining (PCR) primary total knee arthroplasty (TKA) prosthetic designs on knee biomechanics during level walking 1-year after surgery. The multi-radius (MR) design creates at least two instantaneous flexion axes by changing the radius of curvature of the femoral component throughout the arc of knee motion. The femoral component of the single-radius (SR) design has only one radius and therefore a fixed axis.

Methods:

Subjects scheduled for computer-navigated TKA (n = 37: SR n = 20 [9M, 11F], MR n = 17 [8M, 9F]; 69.8 ± 7.1 years, 87.6 ± 20.8 kg, 1.68 ± 0.09 m), and demographic-matched controls without knee pathology n = 23 [13M, 10F], provided informed consent under the Banner IRB (Sun Health panel). All surgical subjects received similar pre-, peri-, and post-operative care under the direction of three surgeons from a single orthopedic practice. Position and force data were collected using 28 reflective markers (modified Helen Hayes [Kadaba et al 1990]) tracked by ten digital IR cameras (120 Hz) (Motion Analysis Corp., Santa Rosa, CA) and four force platforms (1200 Hz) (AMTI, Watertown, MA) embedded in an 8m walkway. Data were recorded and smoothed (Butterworth filter, 6 Hz) using EVaRT 5.0.4 software (Motion Analysis Corp.). Gait cycle parameters were calculated using the ‘Functional Hip Center’ and ‘Original Knee Axis’ models in Orthotrak 6.6.1 (Motion Analysis Corp.). Data from each group were height and weight normalized and ensemble averaged by affected limb (right limb for controls) using custom code written in Labview (National Instruments Corp, Austin, TX). Descriptive statistics for the maximum and minimum knee kinematic, kinetic, and temporal spatial values in the stance and swing phases of the gait cycle were generated for each group. Between-group comparisons were made using an ANOVA with post hoc testing as appropriate (SPSS 14.0 (SPSS Inc, Chicago, IL)).

Background

Large diameter chrome cobalt modular heads in hip replacement surgery have caused one of the biggest challenges to face orthopaedic surgeons, manufacturers and regulators in a generation. Increasing numbers of retrieved implants offer the opportunity to look in detail at the modes of failure of these devices.

Methods

We have examined the mechanical behaviour of the head taper/trunnion using a variety of techniques including: 1.

mechanical testing in a custom-made jig

INTRODUCTION

Human beings are diverse in their physical makeup while implants are often designed based on some key measurements taken from the literature or a limited sampling of patient data. The different implant sizes are often scaled versions of the ‘average’ implant, although in reality, the shape of anatomy changes as a function of the size of patient. The implant designs are often developed based on a certain demographic and ethnicity and then, simply applied to others, which can result in poor design fitment [1]. Today, with the increasing use of 3D medical imaging (e.g. CT or MRI), it is possible to analyze 3D patient anatomy to extract features, trends and population specific shape information. This can be applied to the development of new ‘standard implants’ targeted to a specific population group [2].

PATIENTS & METHODS

Our population analysis was performed by creating a Statistical Shape Model (SSM) [3] of the dataset. In this study, 40 full Chinese cadaver femurs and 100 full Caucasian cadaver femurs were segmented from CT scans using Mimics®. Two different SSMs, specific to each population, were built using in-house software tools. These SSMs were validated using leave-one-out experiments, and then analyzed and compared in order to enhance the two population shape differences.

Introduction

Published literature that examined pre-operative Body Mass Index (BMI) with Total Knee Arthroplasty (TKA) outcomes have shown conflicting data. Some show that higher BMI and is associated with poorer post-TKA function and HRQoL outcomes, but not others.

The aim of our analyses is to identify the relationship of pre-operative obesity with the outcomes of TKA, including physical and mental functional limitations.

Methods

We performed a prospective analysis of a consecutive series of 191 patients, who had underwent TKA from March 2006 to February 2011, performed by a single surgeon, at Singapore General Hospital, Singapore. Patients were eligible if they had met the following criteria: primary, unilateral TKA, using fixed bearing, posterior stabilized prostheses, under computer assisted surgery system. Patients were reviewed clinically at 6 months and 2 years post-operatively.

Patients were stratified into non-obese (BMI <30 kg/m2), mildly obese (BMI 30 to 35) and highly obese (BMI ≥35) groups. Outcome measures evaluated include: SF-36, Oxford knee score and Knee Society Score.

Introduction:

The outcome of previous cemented total hip arthroplasty has been reported to be inferior in renal transplant patients because of poor bone stock resulting from long-term steroid use. Moreover, as renal transplant patients remain on immunosuppressant therapy for life, higher levels of overall morbidity must be considered. We evaluated the mid-term results of cementless total hip arthroplasty in renal transplant recipients with osteonecrosis of the femoral head, and compared those with age and sex matched osteonecrosis patients that had not undergone organ transplantation or been treated with long-term steroid.

Materials & Methods:

Between October 1997 and October 2008, 45 consecutive primary cementless total hip arthroplasties were performed in 30 patients with advanced osteonecrosis of the femoral head after renal transplantation. There were 18 males (27 hips) and 12 females (18 hips) of overall mean age 44 years (22 to 68). The clinical and radiographic results of cementless total hip arthroplasty in these 45 hips were compared with those of 96 sex and age-matched osteonecrotic hips of 72 patients that had not undergone organ transplantation or long-term steroid use. Patients were evaluated at surgery and at a mean of 7.2 years (range, 2–13 years) postoperatively.

Introduction

Several studies have described the relationship between the joint line and bony landmarks around the knee. However, high inter-patient variation makes these absolute values difficult in use.

This study was set up to validate the previously described distances and ratios on calibrated full limb standing X-rays and to investigate the accuracy and reliability of these ratios as a tool for joint line reconstruction

Methods:

One hundred calibrated full-leg standing radiographs obtained from healthy volunteers were reviewed (fig 1). Distances from the medial epicondyle, the lateral epicondyle, the adductor tubercle, the fibular head and the proximal center of the knee (CJD) to the virtual prosthetic joint line were determined (fig 3). This prosthetic joint line was created by introducing a virtual distal femoral cutting block with a valgus angle of 6° on the full-leg radiographs.

The adductor ratio was defined as the distance from adductor tubercle to the joint line divided by the femoral width.

The correlation with the femoral width, the CJD and the limb alignment was analysed using linear regression analysis. The accuracy and reliability of the use of the ratio of the distance of the adductor tubercle, the medial epicondyle and the CJD relative to the femoral width to reconstruct the joint line was calculated.

Methods:

44 consecutive knees of 44 patients with medial osteoarthritis underwent TKR for nomination in this study. All operations were conducted by a single surgeon using a mid vastus approach with cemented posterior stabilized (PS) implant and patellar resurfacing. Patients were targeted for full weight bearing the next day.

Patients were divided into 3 groups of preoperative FTA: 174–180 degrees (11 knees), 181–189 degrees (17 knees), and more than 190 degrees (16 knees). Walking ability was assessed by gait speed and width of step. Balance was measured by a “Functional Reach Test (FR),” which is the difference between arm's length and maximal forward reach (Duncan PW et al. 1990), a “Timed Up and Go Test (TUG),” the time interval for a patient rise from an arm chair, walk 3 meters, and return (Podsiadlo and Richardson 1991), and the capacity to stand on one leg (one leg standing time trial). Every measurement was performed prior to the operation (pre-op), and 4 weeks after operation (post-op 4w). The recovery rate (%) was defined as post-op 4w/pre-op ×100. Data were analyzed by one-way ANOVA, and then differences among means were analyzed using Bonferroni procedures. P-values lower than 5% are regarded as significant.

Result:

The recovery rate of walking speed and TUG showed significant improvement in the FTA more than >190 degree group than that of 174–180 degree group. Every other result showed a higher recovery rate for the >190 degree group, although results were not statistically significant.

INTRODUCTION:

A discrepancy exists between biomechanical and clinical outcome studies when comparing cruciate-retaining (CR) versus posterior stabilized (PS) component designs. The purpose of this study is to re-evaluate experimental model results using half-body specimens with intact extensor mechanisms and navigation to evaluate PS and CR component gaps though an entire range of motion.

METHODS:

A custom-designed knee testing apparatus was used for secure anchoring of the lower half of cadaver pelvic, allowing full range of knee motion and the application of traction throughout that range. Eight sequential testing regimens: were conducted with knee intact, with CR TKA in place, with PS TKA with quadriceps tendon in place, with PS TKA with sectioned quadriceps tendon in place, with and without traction at each stage. At each stage, a navigated knee system with dedicated software was used to record component gapping through a full range of motion from 0° to 120°. The amount of traction used was 22N. Each knee (n = 10) was taken through 6 full ranges of motion at every stage. At each stage, corroboration of navigation findings was attempted using a modified gap balancer to take static gap measurements at 0° and 90° with 12 in. lbs of torque was applied.

Introduction:

The earliest evidence of particle-induced response is found in the synovium, leading to osteolytic defect. The degree of synovitis can be quantified by magnetic resonance imaging (MRI). This is the first long-term, prospective, matched-pair study using MRI to analyze wear-induced synovitis and osteolysis between rotating-platform posterior-stabilized (RP-PS), fixed-bearing metal-back (FB-MB), and all-polyethylene tibial (APT) designs in active patients with identical femoral components and polyethylene.

Methods:

From September 1999 to October 2001, a matched-pair analysis of 24 TKAs (18 patients, 3 groups: 8 RP-PS, 8 FB-MB, and 8 APT) was performed. TKAs were matched for age, sex, body mass index (BMI), and University of California Los Angeles (UCLA) activity scores. All patients underwent MRI using MAVRIC (multi-acquisition variable-resonance image combination) knee protocol designed to reduce metal susceptibility artifact. Images were evaluated for volumetric measure of synovitis and/or osteolysis and presence of fibrous membrane formation at the cement-bone interface.

Introduction:

Proper component orientation and soft tissue balancing are essential for longevity of total knee arthroplasty (TKA), especially in young and active patients. The aim of this study was to evaluate long-term results and quality of TKA in young and active patients with extension first gap balancing technique, in 2 Posterior-Stabilized (PS) total knee designs with identical femoral component.

Material and Methods:

43 consecutive Rotating-Platform (RP-PS, 33 patients) and 38 Fixed-Bearing (FB-PS, 29 patients) with University of California Los Angeles (UCLA) activity score of 5 or above and mean age was 53 ± 1.5 years were followed prospectively for a minimum of 10 years. 18 random TKAs were analyzed for component rotation using MRI.

Background and Purpose:

Modularity of the tibial component in total knee arthroplasties (TKA) has many surgical benefits. It also reduces inventory related expenses but increases implant cost. The resulting locking mechanism micromotion that leads to non-articular microwear and has been an accepted consequence of modularity. The purpose of this study is to evaluate the risk of revision (all-cause and aseptic) of a monoblock all-polyethylene tibial component compared to a fixed bearing modular tibial construct with the same articular geometry while adjusting for potential confounders in a community based sample of primary TKAs. In addition, younger and older patient specific risk of revision was evaluated.

Method:

A retrospective analysis of prospectively collected data from a Total Joint Replacement Registry (TJRR) was conducted. All 27,657 primary TKAs enrolled between 2001 and 2010 performed for any diagnosis with the same implant from a single manufacturer were included in the study. Patient characteristics, as well as surgeon, hospital, procedure, and implant characteristics were compared by the main exposure of interest, i.e. the type of tibial prosthesis (monoblock all-polyethylene vs. metal-backed modular). The main endpoints of the study were all-cause and aseptic revisions only. Descriptive statistics and Cox-regression models were employed. Hazard ratios (HR) and 95% confidence intervals (CI) are provided.

Background:

The safety implications of achieving high flexion after TKA and the use of high flexion prostheses remain issues of concern. It is possible that different designs have different clinical and radiological results and complications, such as, early aseptic loosening. However, little information is available on the clinical results of TKAs performed using single-radius, high-flex posterior stabilized design. Accordingly, this study was undertaken to document results of single-radius, high-flex posterior stabilized TKAs with minimum 7-year follow-up.

Methods:

From April 2003 to February 2006, 308 patients (455 knees) underwent TKA using single-radius, high-flex posterior stabilized design and among those patients, 251 patients (388 knees) included in this study who were able to be followed up for a minimum 7 year. Clinical results were evaluated using Knee Society Knee scores (KSKS) and Knee Society Function scores (KSFS) at last follow-up. The passive knee flexion was measured using a goniometer before and after surgery. The survival rate of the implants and implant-specific complications such as osteolysis or loosening were investigated. The osteolysis or loosening around the components was recorded according to the Knee Society Radiological scoring System.

Introduction:

Infection as an indication for revision has increased to 12% of the total revisions (UK NJR 9^th report). However, it is next to impossible to find out the cause for a delayed prosthetic infection. With increasing number of arthroplasty procedures, is there a need for prophylactic antibiotics in patients with prostheses?

Methods:

At London Knee Meeting 2012, a total of 163 surgeons were asked to take part in a survey. This was to find out if they knew of any existing guidelines for prophylaxis for dental procedures, if there was a need to practice more uniformly, and if they recommend such prophylaxis to their patients routinely. The grade of the surgeon and their experience in years was also noted.

Introduction:

The clinical significance of serum metal ion levels alone in patients with stemmed MoM hip arthroplasty remains uncertain. This study aims to measure the metal ion levels in patients with unilateral and bilateral hip arthroplasty to see whether or not the patients with bilateral hips have higher metal ions.

Patients and Methods

All the patients with bilateral MoM hip arthroplasty were identified from the research database. These patients were then matched with those in a similar age group who had a unilateral hip arthroplasty, but same University of California Los Angeles (UCLA) activity score. The UCLA activity scores along with other hip scores have been previously gathered for all the patients. Both sets of patients then had measurement of serum cobalt and chromium levels. The results were analyzed and compared.

Introduction:

Wear, wear-associated osteolysis, and instability are the most common reasons for revision total hip arthroplasty. These failures have been shown to be associated with acetabular component malpositioning. However, optimal acetabular component orientation on a patient-specific basis is currently unknown. The current study uses CT to assess acetabular orientation in a group of unstable hips as compared to a control group of stable hips.

Methods:

Our institutional database of CT studies performed in the region of the hip beginning in February of 1998 (41,975 CT studies) was compared against our institutional database of revision total hip arthroplasties beginning in August of 2003 (2262 Revision THA) to identify CT studies of any hip treated for recurrent instability by revision of the acetabular component. Twenty hips in 20 patients with suitable CT studies were identified for the study group. Our control group consisted of 99 hips in 93 patients who had CT studies either for computer-assisted surgery on the contralateral side or for assessment of osteolysis. Using the CT data, the AP plane (APP) was defined, supine pelvic tilt was measured, and cup orientation was calculated by fitting a best fit plane to 6 points on the rim of the acetabular component. Cup orientation was calculated in degrees of operative anteversion and operative inclination according to the definitions of Murray. Both absolute cup position relative to the APP and tilt-adjusted cup position¹ were calculated.

INTRODUCTION:

Good survival rates of cementless hip stems serve as motivation for further development, just like modular implant systems or short stems. New aims are worth striving for, e.g. soft tissue or bone sparing options with similar survival rates in case of short stems. Even minimal design modifications might result in complications, e.g. missing osseointegration, loosening of the implant or painful stem, as shown in the past.

One of these developments is the Biomet – GTS™ stem [Fig. 1], a hybrid between conventional cementless straight stem and potentially sparing short stem.

Aim of this biomechanical study was to analyze, if the biomechanical behavior of the stem is comparable to a clinically proofed design with respect to the stem fixation in the bone and to the mechanical behavior of the stem itself. That's why the primary stability of the GTS™ stem has been determined and subsequently was compared to the Zimmer – CLS® stem.

MATERIAL & METHODS

Four GTS™ stems and four CLS® stems were implanted standardized in eight synthetic femurs. Micromotions of the stem and the bone were measured at different sites. A high precision measuring device was used to apply two different cyclic load situations: 1. Axial torque of +/−7 Nm around the longitudinal stem axis to determine the rotational implant stability. 2. Varus-valgus-torque of +/−3, 5 Nm to determine the bending behavior of the stem. Comparing the motions of the stem and femur at different sites allowed the calculation of relative micromotions at the bone-implant-interface.

Introduction:

Extensive bone defects of the proximal femur e.g. due to aseptic loosening might require the implantation of megaprostheses. In the literature high loosening rates of such megaprostheses have been reported. However, different fixation methods have been developed to achieve adequate implant stability, which is reflected by differing design characteristics of the commonly used implants. Yet, a biomechanical comparison of these designs has not been reported.

The aim of our study was to analyse potential differences in the biomechanical behaviour of three megaprostheses with different designs by measuring the primary rotational stability in vitro.

Methods:

Four different stem designs [Group A: Megasystem-C® (Link), Group B: MUTARS®(Implantcast), Group C: GMRS™ (Stryker) and Group D: Segmental System (Zimmer); see Fig. 1] were implanted into 16 Sawbones® after generating a segmental AAOS Typ 2 defect.

Using an established method to analyse the rotational stability, a cyclic axial torque of ± 7.0 Nm along the longitudinal stem axis was applied. Micromotions were measured at defined levels of the bone and the implant [Fig. 2]. The calculation of relative micromotions at the bone-implant interface allowed classifying the rotational implant stability.

Background:

Conventional, extramedullary (EM) tibial alignment guides are only 65%–88% accurate in creating a tibial resection within 2° of perpendicular to the tibial mechanical axis in total knee arthroplasty (TKA). The purpose of this study was to compare the overall, tibial component alignment, and the surgeon's ability to achieve a specific, intraoperative goal for alignment between a portable, navigation system (KneeAlign™) and conventional, EM alignment guides.

Methods:

One hundred patients were enrolled in a prospective, randomized controlled study. Fifty patients received a TKA using the KneeAlign™ to perform the tibial resection, and 50 patients an EM alignment guide. Standing AP hip-to-ankle radiographs and lateral knee-to-ankle radiographs were obtained at the first, postoperative visit.

Background:

Numerous studies have reported the importance of acetabular component positioning in decreasing dislocation rates, the risk of liner fractures, and bearing surface wear in total hip arthroplasty (THA). The goal of improving acetabular component positioning has led to the development of computer-assisted surgical (CAS) techniques, and several studies have demonstrated improved results when compared to conventional, freehand methods. Recently, a computed tomography (CT)-based robotic surgery system has been developed (MAKO™ Robotic Arm Interactive Orthopaedic System, MAKO Surgical Corp., Fort Lauderdale, FLA, USA), with promising improvements in component alignment and surgical precision. The purpose of this study was to compare the accuracy in predicting the postoperative acetabular component position between the MAKO™ robotic navigation system and an imageless, CAS system (AchieveCAS, Smith and Nephew Inc., Memphis, TN, USA).

Materials and Methods:

30 THAs performed using the robotic navigation system (robotic cohort) were available for review, and compared to the most recent 30 THAs performed using the imageless, CAS system (CAS cohort). The final, intraoperative reading for acetabular abduction and anteversion provided by each navigation system was recorded following each THA. Einsel-Bild-Roentgen analysis was used to measure the acetabular component abduction and anteversion based on anteroposterior pelvis radiographs obtained at each patient's first, postoperative visit (Figure 1). Two observers, blinded to the treatment arms, independently measured all the acetabular components, and the results were assessed for inter-observer reliability.

Comparing the difference between the final, intraoperative reading for both acetabular abduction and anteversion, and the radiographic alignment calculated using EBRA analysis, allowed assessment of the intraoperative predictive capability of each system, and accuracy in determining the postoperative acetabular component position. In addition, the number of acetabular components outside of the “safe zone” (40° + 10° of abduction, 15° + 10° of anteversion), as described by Lewinnek et al., was assessed. Lastly, the operative time for each surgery was recorded.

Introduction

After TKR, excessive tension within the lateral retinaculum can lead to joint instability, component wear, stiffness and pain. The spatial distribution of strain in the lateral retinculum is unknown, both in the native knee and after TKR. In this study we measure the magnitude and distribution of mechanical strain in the lateral retinaculum with knee flexion, both in the native knee and after TKR. We hypothesize that: 1.

Strain in the lateral retinaculum will increase as a function of flexion.

Materials and Methods

A fiduciary grid of approximately 40–70 markers was attached to the exposed lateral retinacula of five fresh frozen cadaveric knees in order to allow tracking of soft-tissue deformation. Each knee was flexed from 0–120° in a 6 degree-of-freedom custom activity simulator that physiologically loaded the knee during a squatting maneuver. During simulation, the displacement of each fiduciary point was measured using visible-light stereo-photogrammetry. The fiduciary grid divided into four distinct regions for strain analysis. Using the grid of the native knee in full extension as the initial state, the average principal strain in each region was calculated as a function of flexion. Measurements were repeated after TKR was performed using a contemporary implant system.

Introduction:

The sealing function of the acetabular labrum is central to the stability of the hip and the health of the joint. Disruption of the labrum has been shown to reduce intra-articular pressure and increase the rate of cartilage consolidation during static loading. Functional activities require movement of the hip through wide ranges of joint motion which disrupt joint congruency, and thus may alter the seal. This study was performed to test the hypothesis that the sealing function of the labrum varies with the position of the hip during functional activities.

Methods:

Six fresh cadaveric hip joint specimens were obtained from donors of average age 45.5 ± 16.1 years (range 25–63 years). Each specimen was dissected free of soft tissue, leaving the capsule and labrum intact, potted in mounting fixtures, and placed in a loading apparatus. Catheters were inserted into the central and peripheral compartments of each hip to allow infusion of fluid and monitoring of compartment pressures via miniature transducers (OMEGA Engineering, Inc). After application of a joint load of 0.50 BW, fluid was introduced into the central compartment at a constant rate until transport was indicated by a rise in pressure within the peripheral compartment. These measurements were performed with each hip placed in 10 functional positions ranging from −5 to 105 degrees of flexion, −5 to 13 degrees of abduction, and −25 to 35 degrees of external rotation simulating the sequential stages of gait, stooping, and pivoting. Motion analysis was performed via reflective marker arrays attached to the femur and pelvis to allow computer visualization of the position of the pelvis and femur using CT reconstructions. In each hip position, we measured the peak pressure (kPA) developed within the central compartment prior to fluid transfer to the peripheral compartment.

Introduction

The failure rate of Total Hip Replacement (THR) has been shown to be strongly influenced by the nature of the articulating interfaces, with Metal-on-Metal (MoM) articulations having three times the failure rate of Metal-on-Polyethylene (MoP) components. It has been postulated that this observation is related to edge wear and increased bearing torque of large MoM heads, which would lead to increased loading and wear at the head taper junction and, subsequently, to the release of metal ions and corrosion products. This suggests that taper wear and corrosion should not be as prevalent in large head MoP implants as in large head MoM implants. This study was undertaken to test the hypotheses that: (i) MoM implants exhibit higher rates of corrosion and fretting at the head taper junction than MoP implants, and that (ii) the severity of corrosion and fretting is greater in components of larger head diameter.

Materials and Methods

Our study included 90 modular implants (41 MoM; 49 MoP) retrieved during revision hip arthroplasties performed between 1992 and 2012. Only retrievals with head diameters greater than 32 mm were included, and trunnion sizes ranged from 10/12 mm to 14/16 mm with 12/14 mm being the most common size. The stem trunnion and head taper surfaces were examined under stereomicroscope by a single observer. Each surface was scored for both corrosion (using a modified Goldberg scoring system) and fretting (using the standard Goldberg scoring system). For both the trunnion and head tapers, the student's t-test was used to determine if differences exist in the severity of corrosion or fretting between the MoM and MoP groups and between different head sizes of the same articulation type.

Background:

The use of registry data to detect and eliminate inferior devices is based on the assumption that the results of the first cases performed with a new device are indicative of how the same implant would perform with widespread usage. However, existing registry data clearly proves that the performance of individual implants is very surgeon dependent. In this study we utilized a computer simulation of a large implant registry to address the question: How does the pairing of different surgeons with different implants affect the ability of registries to correctly identify inferior devices?

Materials and Methods:

A synthetic implant registry was created consisting of 10,000 patients who underwent joint replacement performed by 100 different surgeons using 5 different implants. Hazard functions representing the relative risks for revision associated with individual patients and surgeons were derived from the annual reports of implant registries. The cumulative revision rates (CRR values) of the 5 hypothetical implants were fixed at nominal values of 10%, 15%, 20%, 25%, and 30% at 15 years post operation vs. 10% for average implants. The surgeons were ordered according to their individual probabilities of a revision at less than 15 years post-op. Each surgeon was placed in one of 8 subsets comprised of 12.5% of the total surgeon pool, ranging from the lowest to the highest risk of revision. Patients, surgeons, and implants were randomly matched in an iterative fashion to simulate 500 separate RCTs, starting with the group of surgeons of with the lowest risk, and then repeating the simulation using surgeons with the lowest and second lowest risk of revision. This process was repeated iteratively until all surgeons were enrolled.

Introduction

Tribo-chemical damage of modular taper junctions is often observed at revision THR and may be a contributing factor to chronic inflammation of peri-prosthetic tissues through generation of chromium rich corrosion products. At the time of revision, surgeons may elect to leave the primary femoral stem in situ and replace the original femoral head with a new component. This decision is based on the assumption that the interface formed between the original trunnion and the new bore is capable of withstanding the loads and torques applied during use, without failure of the new interface. This study was performed to determine the extent to which the mechanical properties of the taper interface are degraded with varying degrees of tribo-chemical damage secondary to prior implantation.

Materials and Methods

Fifteen CoCr femoral heads (DePuy: 6, Smith & Nephew: 5; Zimmer: 4) were retrieved at revision THR and were examined with stereomicroscopy. The surface of each bore was scored for the presence of fretting and corrosion using the grading system of Goldberg et al. Nine additional heads in original (unimplanted) condition (3 per manufacturer) were also selected to act as controls. Each head was manually assembled on a matching unimplanted TiAlV trunnion in a mechanical testing machine (MTS Bionix) and loaded at 500N/sec to a maximum assembly load of 4000N. The head/trunnion specimen was then mounted in a torsional loading fixture and immersed in bovine serum. A cyclic torque was applied to the head with an initial maximum value of 2 Nm. The specimen was unloaded and held for a 30 sec wait period and the torsional loading was repeated to a peak value of 4 Nm. With each torsional cycle the peak torque was increased by 2 Nm until the taper junction underwent rotational failure. During testing, relative motion between the femoral head and the trunnion was measured with a displacement transducer (DVRT-3, MicroStrain, accuracy = ± 0.1%, resolution = 1.5 μm, hysteresis & repeatability = ± 1 μm). A separate disassembly test was performed by first assembling each specimen with 4000N and then applying a distraction force at 0.008 mm/sec until separation.

Introduction:

One method of femoral head preservation following avascular necrosis (AVN) is core decompression and Tantalum Rod insertion. There is, however, a published failure rate of up to 32% at 4 years. The purpose of the present study was to document the clinical and radiological outcome following Total Hip Arthroplasty (THA) subsequent to failed Tantalum Rod insertion.

Methods:

Twenty-five failed Tantalum Rod insertions subsequently requiring THA were identified from a prospectively updated database. Seventeen patients met minimum 2 year clinical and radiographic follow-up criteria. St. Michael's Hip (SMH) scores were compared to a matched cohort of patients with THA for AVN without prior Tantalum Rod insertion. Postoperative radiographs were reviewed assessing component alignment, linear wear (Dorr & Wan) and presence of tantalum residue within the joint space.

Introduction:

In posterior cruciate ligament-retaining total knee arthroplasty (CR-TKA), a small bone block (bony island) is often preserved to protect the attachment of the posterior cruciate ligament (PCL), which might be troublesome. In contrast, we prefer to resect the tibial plateau completely to facilitate the surgical procedure. However, there is concern over the increase of the flexion gap due to partial detachment of the PCL. The purpose of the present study is to evaluate the influence of bony island resection on the flexion gap.

Methods:

The subjects were 20 consecutive patients who underwent posterior cruciate ligament-retaining total knee arthroplasty for varus osteoarthritis. There were 18 women, two men, with a mean age of 71.8 years (range, 62–82 years). All operations were performed using posterior cruciate ligament-retaining prosthesis (MERA Quest Knee System, Senko Medical Instrument Manufacturing, Tokyo) by the same senior author with a measured resection technique. The knees were exposed with a medial parapatellar approach. The distal femur was cut and the tibial plateau resection was made with preserving the bony island. The central joint gaps in 90° flexion and full extension were measured using a tensioning device (Offset Repo-Tensor, Zimmer, Warsaw, IN) at 40-lb distracting force. Then, after the resection of the bony island, the central joint gaps were measured by the same method. In addition, the posterior tilt of the tibial resection and the depth of the lateral tibial cut were measured.

Introduction

In vitro findings (Bladed CL et al. ORS 2011 and J Biomed Mater Res B Appl Biomater, 2012) have suggested that UHMWPE wear particles containing vitamin-E (VE) may have reduced functional biologic activity and decreased osteolytic potential. Currently, there is no in vivo data determining the effects of wear debris from this new generation of implants. In this study we hypothesized that particles from VE-stabilized, radiation cross-linked UHMWPE (VE-UHMWPE) would cause reduced levels of osteolysis in a murine calvarial bone model when compared to virgin gamma irradiated cross-linked UHMWPE.

Methods

Study groups: 1). Radiation cross-linked VE-UHMWPE, 0.8% by weight, diffused after 100 kGy; 2). Radiation cross-linked virgin UHMWPE (virgin UHMWPE); 3). Shams. Particle generation and implantation: UHMWPE was sent to Bioengineering Solutions for particle generation. After IACUC approval, C57BL/6 mice (n = 12 for each group) received 3 mg of particulate debris overlying the calvarium and euthanized after 10 days. Micro-CT scans: Performed using an X-Tek-HMX-ST-225 with 70 kV voltage and 70 μA current. Topographical Grading Scale: Each calvarial bone was blindly scored with the following scale: 0 = No osteolysis, defined as intact bone; 1 = Minimal osteolysis, affecting 1/3 or less of the bone area; 2 = Moderate osteolysis, affecting at least 2/3 of the bone area; 3 = Severe osteolysis, defined as completely osteolytic bone. Histology H&E and TRAP staining was performed. Statistical Analysis: Inter-rater analysis was performed using Cohen's kappa analysis. Inter-rater coefficient >0.65 was considered as high inter-rater agreement. Comparison between groups was made using one-way ANOVA with post hoc Bonferroni correction for multiple comparisons. Correlations are reported as Spearman's rho. A p-value<0.05 was considered statistically significant.

Introduction:

Acetabular component orientation has been linked to hip stability as well as bearing mechanics such as wear. Previous studies have demonstrated wide variations of cup placement in hip arthroplasty using conventional implantation techniques which rely upon either anatomic landmarks or the use of commercial positioning guides. Enabling technologies such as navigation have been used to improve precision and accuracy. Newer technologies such as robotic guidance have been postulated to further improve accuracy. The goal of our study was to evaluate the clinical reproducibility of a consecutive series of haptically guided THR.

Methods:

119 patients at 4 centers were enrolled. All patients had preoperative CT scans for the purpose of planning cup placement in lateral opening and version using proprietary software (Mako, Ft. Lauderdale, FL). All procedures were performed using a posterolateral approach. Following bone registration, acetabular preparation and component position is performed using haptic guidance. Final implant postion is ascertained by obtaining 5 points about the rim of the acetabular component and recorded. At 6 weeks, all patients had AP and cross-table lateral radiographs which were then analyzed for cup abduction and anteversion using the Hip Analysis Suite software. The goal was to determine the variability between desired preoperative plan, intraoperative measurement and postoperative results.

Background:

The rising number of morbidly obese patients may have significant consequences on the health care system. It may alter the effectiveness, safety as well as cost of certain surgical procedures. Reverse shoulder arthroplasty (RSA) is rapidly gaining in popularity. We investigated the effect of morbid obesity on outcomes, complications, disposition and cost in morbidly obese patients undergoing RSA in a 1: 3 case control series.

Methods:

Our joint registry was searched for all patients undergoing primary RSA (excluding fractures) with a minimum of 24 months follow-up from 2003–2010; 21 patients with Body Mass Index (BMI) > 35 were identified (follow-up 45 ± 16 months, 17 females and 4 males, age 69 ± 7) and compared to 63 matched control patients with BMI<30 (follow-up 48 ± 20, 50 females, age 71 ± 6). Outcome data was obtained pre- and postoperatively. Patients' Charlson-Deyo comorbidity index (CDI), total comorbidities, operative time, blood loss (EBL), hospitalization length, disposition, cost and complications were recorded.

Introduction

Increasing attention to the functional outcome of total knee arthroplasty (TKA) has demonstrated that many patients experience limitations when attempting to perform demanding activities that are normal for age-matched peers, primarily because of knee symptoms. Episodes of instability following TKA are most commonly reported during activities in which significant transverse or torsional forces are supported by the joint with relatively low joint compression forces, including stair-descent and walking on sloped or uneven surfaces. This study was performed to examine the influence of conformity between the femoral and tibial components on the Antero-Posterior (AP) stability of knee during stair descent.

Methods

Six cadaveric knees were loaded in a six degree-of-freedom joint simulator, with the application of external forces simulating the action of the quadriceps and hamstring muscles and the external loads and moments occurring during stair descent, including the stages of terminal swing phase, weight-acceptance phase (prior to and after quadriceps contraction) and mid-stance. During these manoeuvres, the displacement and rotation of the femur and the tibia were measured with a multi-camera high resolution motion analysis system (Fig. 1). Each knee was tested in the intact and ACL deficient condition – and after implantation of total knee prosthesis with Cruciate-Retaining (CR), Cruciate-Sacrificing with an intact PCL (CS + PCL), Cruciate-Sacrificing with an absent PCL (CS-PCL) and Posterior-Stabilizing (PS) tibial inserts (Figs 2 and 3).

Introduction:

Reverse total shoulder arthroplasty (RTSA) has become an accepted surgical treatment for patients with severe deficiency of the rotator cuff. Despite the utility of RTSA in managing difficult shoulder problems, humeral rotation does not reliably improve and may even worsen following RTSA. Several approaches to increase active external rotation (aER) postoperatively have been proposed including the use of concomitant latissimus dorsi tendon transfer (LDTT) or the use of an increased lateral-offset glenosphere (LG). We hypothesized that clinical outcome and range of motion after RTSA with a +4 mm or +6 mm LG would be comparable to RTSA with LDTT in patients with a lack of aER preoperatively.

Methods:

An IRB-approved, prospective, single surgeon RTSA registry was reviewed for patients treated with LDTT or LG for preoperative aER deficiency with minimum 1-year follow-up. Patients qualified for aER deficiency if they had a positive ER lag sign or less than or equal to 10 degrees of aER preoperatively. Matched control groups with patients that did not have preoperative lack of aER and were not treated with LDTT or LG were included for comparison. Outcomes measures included Constant-Murley score (CMS), American Shoulder and Elbow Surgeons (ASES) score, Subjective Shoulder Value (SSV), ASES Activities of Daily Living (ADL) score, Visual Analogue pain Scale (VAS), active forward elevation (aFE), active internal rotation (aIR), and aER. An independent, institutional biostatistician performed statistical analyses.

Introduction:

Reverse total shoulder arthroplasty (RTSA) has become instrumental in relieving pain and returning function to patients with end-stage rotator cuff disease. A distalized and medialized center of rotation in addition to a semi-constrained implant design allows the deltoid to substitute for the non-functioning rotator cuff. The purpose of this study was to examine the relationship between specific deltoid and rotator cuff muscle parameters and functional outcomes following RTSA.

Methods:

Patients undergoing RTSA by a single surgeon were enrolled in a prospective, IRB approved RTSA outcomes registry. Inclusion criteria were diagnosis of cuff tear arthropathy or massive rotator cuff tear, a minimum 2-year follow-up, and a preoperative shoulder MRI. We excluded patients undergoing revision arthroplasty, fracture, and a history of previous open shoulder surgery. For the 28 patients meeting our criteria, the cross-sectional area (CSA) of the anterior, middle, and posterior deltoid were measured on an axial MRI (Figure 1). Fatty infiltration (FI) of the deltoid, supraspinatus (SS), infraspinatus (IS), teres minor, and subscapularis were assessed on sagittal T1-MRI quantitatively via image processing and qualitatively on the 5-point Fuchs scale by a fellowship-trained musculoskeletal radiologist. Outcome measures included active forward elevation (aFE), active external rotation (aER), active internal rotation (aIR), strength in abduction, Constant-Murley score (CMS), Subjective Shoulder Value (SSV), Visual Analogue Scale (VAS) pain, and American Shoulder and Elbow Surgeons (ASES) total and ASES activities of daily living (ADL) scores as assessed by a trained, clinical research nurse. Correlation of deltoid CSA and FI with outcomes measures was analyzed with a Spearman rank correlation coefficient (ρ) with significance at P < .05.

Introduction:

The routine use of posterior hip dislocation precautions is typically utilized postoperatively following total hip arthroplasty via a posterior surgical approach. This has included use of an abduction pillow and limiting adduction, internal rotation and flexion more than 90 degrees for a minimum of 6 weeks postoperatively. This may slow the course of rehabilitation, increase the length of hospital stay and the total cost of the procedure, and add additional anxiety to the patient. We conducted this study to see if posterior hip precautions are necessary after total hip arthroplasty via a posterior approach when the hip meets certain intraoperative criteria for stability.

Methods and Materials:

All patients in our institute undergo routine hip stability testing during primary total hip arthroplasty via a posterior approach. Before October 2010, all of our primary total hip arthroplasty patients were placed on routine hip precautions. We stopped hip precautions in October 2010 for all the patients who were noted to meet hip stability criteria intraoperatively. We prospectively compared the consecutive patients who underwent this procedure without hip precautions with a retrospective control group of patients who had hip precautions.

Introduction

Accurate evaluation of femoral offset is difficult with conventional anteroposterior (AP) X-rays. Routine CT imaging is costly and exposes patients to a significant dose of radiation. The EOS® imaging system is an innovative slot-scanning radiography system that makes possible the acquisition of simultaneous and orthogonal AP and lateral images of the patient in standing position. These 2-dimensional (2D) images are equivalent to standard plane X-rays. Three-dimension (3D) reconstructions are obtained from these paired images according to a validated protocol. This prospective study explores for the first time the value of the EOS® imaging system for comparing measurements of femoral offset obtained from 2D images and 3D reconstructions.

Materials and Methods

Following our standard protocol, we included a series of 100 patients with unilateral total hip arthroplasty (THA). The 2D offset was measured on the AP view with the same protocol as for standard X-rays. The 3D offset was calculated from the reconstructions based on the orthogonal AP and lateral views. Reproducibility and repeatability studies were conducted for each measurement. We compared the 2D and 3D offsets for both hips (with and without THA).

Introduction

Frictional torque is generated at the hip joint during normal gait loading and motion [1]. This study investigated the effect of shell deformation due to press-fit on frictional torque generated at the articulating surfaces of cementless acetabular shells that incorporated fixed and dual mobility bearing designs.

Materials and Methods

Figure 1 lists the study groups (minimum of n = 5). All groups were tested with a 50 mm Trident PSL shell (Stryker Orthopaedics, NJ) and a Ti6Al4V trunnion. Metal-on-Metal specimens were custom designed and manufactured, and are not approved for clinical use. The remaining groups consisted of commercially available products (Stryker Orthopaedics, NJ).

All groups were tested with the shells in deformed and undeformed states.

Deformed Setup: A two-point relief configuration was created in a polyurethane foam block (Figure 2) with a density of 30 lb/ft³ to replicate shell deformation due to press-fit [2]. The blocks were machined to replicate the press-fit prescribed in the shell's surgical protocol. Each shell was assembled into the foam block by applying an axial force at 5 mm/min until it was completely seated.

Undeformed Setup: Each shell was assembled in a stainless steel block with a hemispherical cavity that resulted in a line-to-line fit with the shell OD.

Frictional torque was measured using a physiologically relevant test model [3]. In this model, the specimen block was placed in a fixture to simulate 50° abduction and 130° neck angle (Figure 2). A 2450N side load was applied and the femoral head underwent angular displacement of ± 20° for 100 cycles at 0.75 Hz. The articulating surfaces were lubricated with 25% Alpha Calf Fraction Serum.

Peak torque was observed towards the end or the beginning of each cycle where the velocity of the femoral head approaches 0 and the head changes direction. This torque is referred as maximum static frictional torque. Specimen groups were statistically compared with a single-factor ANOVA test and a Tukey post-hoc test at 95% confidence level. Paired t-tests were performed to compare individual groups in deformed and undeformed states.

Introduction:

Unicompartmental knee arthroplasty (UKA) is a well established method for treatment of single compartment arthritis. However, a subset of patients still present with continued pain after their procedure in the setting of a normal radiographic examination. We propose the use of magnetic resonance imaging (MRI) as a useful modality in determining the etiology of symptoms in symptomatic unicompartmental knee arthroplasties.

Materials & Methods:

An IRB-approved retrospective analysis of 300 consecutive unicompartmental knee arthroplasties between 2008–2010 found 28 cases symptomatic for continued pain. Magnetic resonance imaging was performed with a 1.5 T Surface Coil unit after clinical and radiographic assessment. MRI evaluation included assessment for osteoarthritis, synovitis, osteolysis, and loosening. Validated questionnaires including PAQ, WOMAC and UCLA Activity Score were used for clinical assessment

Objective:

Patient-specific or “custom” total knee replacements have been designed to fit the arthritic knee in primary total knee arthroplasty (TKA) better than “off-the-shelf” implants. Using computer technology, patient-specific cutting-blocks and custom-made implants are created to more accurately fit the contour of the knee and reproduce the anatomic J-curve with the hope of providing a better functional outcome.

Purpose:

This retrospective, matched-pair study evaluates manipulation under anesthesia (MUA) rates in cemented patient-specific cruciate-retaining (PSCR) TKA compared to that in both cemented posterior-stabilized (PS) and non-cemented cruciate-retaining rotating-platform (NC CR RP) TKA.

INTRODUCTION

Acetabular cup orientation is an important element of Total Hip arthroplasty (THA). The purpose of this retrospective case-control study was to compare variability of acetabular cup placement between THA performed via Direct Anterior Approach (DAA) with fluoroscopy in supine position and posterior approach (PA) in lateral position without use of fluoroscopy.

METHODS

Radiographic and clinical records of THAs performed by a single, high volume arthroplasty surgeon at one institution were reviewed. Patients with similar design of uncemented acetabular cup, femoral component and bearing surface were included to form two groups. PA group consisted of 300 THAs performed from May 2006 to June 2009. DAA group consisted of 300 THAs performed from Oct 2009 to Oct 2011 excluding first 100 cases to eliminate the influence of learning curve. Radiographic analysis was done by two independent blinded observers to determine cup inclination and anteversion (Liaw et al) on standardized, 6 week postoperative, standing anteroposterior pelvic radiographs using Picture Archiving and Communication System software (PACS).

Introduction

Modeling the press-fit that occurs in Total Hip Arthroplasty (THA) cementless implants is crucial for the prediction of micromotion using finite element analysis (FEA). Some studies investigated the effect of the press-fit magnitude and found a direct influence on the micromotion [1,2]. They assumed in their model that press-fit occurs throughout the prosthesis. However [3] found using computed tomography measurement that only 43% of the stem-bone interfaces is really in contact. The aim of this study is to investigate the press-fit effect at the stem-bone interface on the implant micromotion.

Methods

Finite element analysis (FEA) was performed on a Profemur® TL implanted into a Sawbones®. The implant orientation was validated in a previous study [4]. All materials were defined as linear isotropic homogeneous. FEA was carried out for the static loading conditions defined by [5] simulating walking fastly. Frictional contact between the bone and the prosthesis was assumed all along the prosthesis with a coefficient μ set to 0, 63 for the plasma spray (Fig. 1a) and 0,39 for the polished surface (Fig. 1b) [6]. Firstly, FEA was performed without press-fit (Fig. 2a) and then press-fit was simulated with an interference of 0,05 mm [2] between stem and bone in specific areas: superior (Fig. 2b), intermediate (Fig. 2c), inferior (Fig. 2d), and cortical alone (Fig. 2e) and finally over the entire surface in contact with the bone. The press-fit effect at the stem-bone interface on the micromotion was investigated. Measurement of the micromotion was realised on different points located on the plasma spray surface by calculating the difference between the final displacement of the prosthesis and the final displacement of the bone.

Background:

Standardized preclinical wear testing cannot replicate the variations of wear rates and wear mechanisms seen in-vivo [1]. Therefore, a lot of studies focused on testing scenarios which replicate a wider range of patient-specific conditions such as different activities or malalignment of components. However, differences between the in-vivo and in-vitro situation regarding the environmental conditions are often neglected.

Considerable differences between the in-vivo and the in-vitro situation are related to the surrounding synovial fluid and its in-vitro substitute (bovine serum). For the in-vivo knee only small volumes (1–4 ml) of synovial fluid are reported [2]. However, for in-vitro testing several hundreds of milliliters of bovine serum are typically used. Therefore, the hypothesis of this study is that fluid volume significantly influences the wear rates in simulator tests.

Material and Methods:

For wear testing an established implant system (Sigma® PFC, DePuy, Warsaw, USA) has been used.

Four wear tests with four different testing volumes of bovine serum were carried out: 250 ml; 150 ml; 75 ml; 45 ml. The testing volume of the original chamber (250 ml) was reduced using solids (Fig. 1). Care was taken, that the contact surfaces of the implants were completely immersed and the fluid level was kept constant in all cases (Fig. 1). The testing fluid was maintained at a temperature of 37 ± 1°.

All wear tests were run displacement controlled according to ISO 14243-3: 2004 on an AMTI knee simulator.

Introduction

Post-operative clinical outcomes of TKA are dependent on a multitude of surgical and patient-specific factors. Malrotation of the femoral and/or tibial component is associated with pain, accelerated wear of the tibial insert, joint instability, and unfavorable patellar tracking and dislocation. Using the transepicondylar axis to guide implantation of the femoral component is considered to be an accurate anatomical reference and is widely used. However, no gold standard currently exists with respect to ensuring optimal rotation of the tibial tray. Literature has suggested that implantation methods, which reference the tibial tubercle, reduce positioning outliers with more consistency than other anatomical landmarks. Therefore, the purpose of this evaluation is to use data collected from intraoperative sensors to assess the true rotational accuracy of using the mid-medial third of the tibial tubercle in 98 TKAs.

Methods

The data for this evaluation was retrieved from 98 consecutive patients who underwent primary TKA from the same highly experienced surgeon. Femoral component rotation was verified in every case via the use of the Whiteside line, referencing the transepicondylar axis, and confirming appropriate patellar tracking. Tibial tray rotation was initially established by location of the mid-medial third of the tibial tubercle. Rotational adjustments of the tibial tray were evaluated in real-time, as the surgeon corrected any tibiofemoral incongruency and tray malpositioning. The initial and final angles of tibial tray rotation were captured with intraoperative video feed, and recorded. A z-test of differences between pre- and post-rotational correction was performed to assess the statistical significance of malrotation present in this cohort.

INTRODUCTION:

Proper tibial rotation has been cited as an important prerequisite to optimal total knee replacement. The most commonly recognized rotational landmark is the medial 1/3^rd of the tibial tubercle. The purpose of this study was to quantify the amount of variability this structure has from a common reference as well as to understand the effects of component design when referencing this structure.

METHODS:

Subjects were prospectively scanned into a Virtual Bone Database (Stryker Orthopaedics, Mahwah, NJ), which is a collection of body CT scans from subjects collected globally. All CT scans displayed cropped bones were excluded. SOMA™ (Stryker) is a unique tool with the ability to take automated measurements of quantities such as distances and angles on a large number of pre-segmented bone samples which was then to perform calculations represented in this study. Demographic information for each subject was recorded were known. For the analysis, the mechanical axis of the tibia (MAT) was established by connecting the center of the proximal tibia to the center of the ankle. From the MAT, a perpendicular resection plane was made at a distance of 9 mm from the most proximal portion of the lateral condyle. This plane was then used as a virtual resection plane to establish the points for the remaining structures which was the medial 1/3^rd of the tibial tubercle and the posterior notch of the PCL insertion. The following axes were identified: 3TT (line between the medial 1/3^rd of the tibial tubercle and the posterior notch of the tibia); 3CTT (line between the medial 1/3^rd of the tibial tubercle and the center of the tibia); and the posterior axis of the tibia (line connecting the two most posterior points of the tibia at the virtual resection plane). Measurements made were the angle of the 3TT Line to the posterior axis and the angle of the 3CTT Line to the posterior axis.

Introduction

Posterior glenoid wear is common in glenohumeral osteoarthritis. Tightening of the subscapularis causes posterior humeral head subluxation and a posterior load concentration on the glenoid. The reduced contact area causes glenoid wear and potentially posterior instability. To correct posterior wear and restore glenoid version, surgeons may eccentrically ream the anterior glenoid to re-center the humeral head. However, eccentric reaming undermines prosthesis support by removing unworn anterior glenoid bone, compromises cement fixation by increasing the likelihood of peg perforation, and medializes the joint line which has implications on joint stability. To conserve bone and preserve the joint line when correcting glenoid version, manufacturers have developed posterior augment glenoids. This study quantifies the change in rotator cuff muscle length (relative to a nonworn/normal shoulder) resulting from three sizes of posterior glenoid defects using 2 different glenoids/reaming methods: 1) eccentric reaming using a standard (nonaugmented) glenoid and 2) off-axis reaming using an 8, 12, and 16° posterior augment glenoid.

Methods

A 3-D computer model was developed in Unigraphics (Siemens, Inc) to simulate internal/external rotation and quantify rotator cuff muscle length when correcting glenoid version in three sizes of posterior glenoid defects using posterior augmented and non-augmented glenoid implants. Each glenoid was implanted in a 3-D digitized scapula and humerus (Pacific Research, Inc); 3 sizes (small, medium, and large) of posterior glenoid defects were created in the scapula by posteriorly shifting the humeral head and medially translating the humeral head into the scapula in 1.5 mm increments. Five muscles were simulated as three lines from origin to insertion except for the subscapularis which was wrapped. After simulated implantation in each size glenoid defect, the humerus was internally/externally rotated from 0 to 40° with the humerus at the side. Muscle lengths were measured as the average length of the three lines simulating each muscle at each degree of rotation and compared to that at the corresponding arm position for the normal shoulder without defect to quantify the percentage change in muscle length for each configuration.