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View my account settingsOsseointegration has been shown to be directly affected by surface roughness and bioactive coatings. This report compares bone response to hydroxyapatite coatings on differing substrate treatments.
Titanium cylinders was implanted bilaterally in the distal femora of 30 rabbits. One of three surface treatments was applied to each implant: plasma sprayed titanium surface without hydroxyapatite coating (P), plasma sprayed titanium surface with hydroxyapatite coating (PHA), and acid-etched surface with hydroxyapatite coating (CHA). Osseointegration was measured at 6 and 12 weeks, by histomorphometry of scanning electron microscopy images of histologic sections taken through the implant at three levels: diaphysis, metaphysis, and intermediate. Bone growth was measured up to 3 mm from the edge of the implant to determine changes in patterns of bone growth.
Overall, bone response was greatest in the diaphyseal sections. Mean osseointegration was significantly different between hydroxyapatite coated and non-hydroxyapatite coated implants (CHA: 74+10%, PHA: 65+12%, and P: 39+10%, p< 0.01). Both hydroxyapatite coated implants demonstrated increased bone growth closer to the implant which dropped off with increasing distance from the implant. Lower and relatively unchanging levels of bone growth were seen in non-hydroxyapatite coated implants.
Osseointegration and bone growth was higher in both hydroxyapatite coated surfaces confirming previous reports. The differences in substrates (acid etched vs. plasma sprayed titanium) did not yield a significant difference in bone growth, suggesting that the hydroxyapatite coating provided a much larger benefit. This study supports the hypothesis that enhanced osseointegration is primarily due to the bioactive coating.
A common finding in acetabular revisions is loss of medial bone stock. Using a standard cementless hemispherical component, alternatives for reconstruction include medialisation of the cup, medial particulate allograft with rim fixation on host bone, or use of a “mega-cup”. A cementless shell that has 6 mm of lateral augmentation is useful in restoring the joint centre while at the same time achieving implant stability and increasing host bone contact without loss of additional bone.
From 1991 to 2000, a total of 142 acetabular revisions were performed with the Arthropor TM DP+6 implant (Joint Medical Products/J& J/DePuy). These patients have been prospectively followed bi-annually with Harris Hip Scores and monitoring of complications and radiographic findings. Average follow-up is 5 years (range 2 to 11 years).
Implant survivorship is 100%. There have been seven re-operations: one for infection (debrided), two for femoral revision and four head/liner changes for recurrent dislocations. Dislocation incidence is 7.8%. The average Total Harris Score at 5 years is 74.3, with an average Harris Pain Score of 34.9 (out of a maximum of 44). Radiographic analysis showed frequent zone 3 radiolucent zones. Initial migration of > 2 mm with subsequent stabilisation occurred in 18%. The joint centre was restored to within 5 mm of the contralateral hip in 85% of cases.
We have found this type of implant to be efficacious in the more common acetabular revisions where the loss of bone stock is mainly medial/cavitary, with an intact posterior column and small medial segmental defects.
In this study we intend to evaluate the outcomes for patients with the Rotaglide mobile meniscal knee prosthesis implanted for osteoarthritis. All patients reviewed had this prosthesis implanted as a primary total knee arthroplasty in Crosshouse hospital.
The minimum follow up period was 5 years (range 5 to 8.2). Patients were assessed clinically by the junior author (CW) and the results were standardised using the Hospital for Specialist Surgery (HSS) knee score. Standard radiographs were taken in AP and lateral planes to assess for loosening using the Knee Society roentgenographic system. Case notes were then examined for evidence of complications in the peri and postoperative complications.
Sixty-five patients (71 knees) were reviewed. There was an excellent clinical outcome with HSS scores of 85 in 97.1% of patients. Two knees (2.9%) were revised, one for meniscal fracture and one for meniscal dislocation. Both these patients also attended for review and were making good progress. Both of these failures occurred early in our series and in a total of 312 knees to date there have been no other meniscal failures. No knees were revised for aseptic loosening and there have been no deep infections.
We feel this prosthesis offers a safe and effective treatment for osteoarthritis with a good clinical outcome at 5 years with a low level of complications.
Genetic defects causing dwarfism occur in approximately 1 in 10 000 live births. There are over 200 types. Another frequent cause of short stature is juvenile rheumatoid arthritis. Most types of dwarfism result in arthrosis of major joints resulting in significant disability. Hip replacement can offer significant improvement in quality of life, but there are inherent difficulties due to size and anatomic variations.
Short stature of less than 4 feet 10 inches was defined as dwarfism. Eight patients meeting this criterion underwent either primary or revision total hip replacement, with six being bilateral, resulting in a total of 14 hips for study (six primaries and eight revisions). The diagnoses were: two JRA, two Mucolipdosis III, one Dyastrophic Dwarfism, one Spondyloepiphyseal Dysplasia, one Thalasemia, and one Congenital Rickets. In eight hips a CT-based custom cementless femoral component was used. Average follow-up was nine years (2 – 14).
The average Total Harris Hip Score improved from 35 pre-operatively to 66 at last follow-up, with the average Harris Pain Score increasing from 10 to 31 (out of a maximum of 44). Of the six primary hips, two hips in the same patient have been revised for combined acetabular and femoral loosening. Of the eight revision hips, there have been three re-operations: one re-revised for acetabular loosening, one re-revised for late hematogenous infection and one head/liner change for recurrent dislocations.
Hip replacement in dwarfs presents a complex technical challenge, but can result in significant improvement in pain, function and quality of life. CT-base custom femoral components are recommended.
Patients with advanced osteoarthritis tend to have limited range of motion; the purpose of this in vivo anatomical study is to identify the anatomical structures responsible for limited knee movement in patients with osteoarthritis.
Forty-two quadriceps releases were performed in patients who had TKA. The releases were carried out utilising subvastus approach and just before proceeding with the knee replacement surgery. The ranges of motion were documented before and after the release using digital photography and lateral portable X-ray. No bony resection was done, and no ligament release was performed. Quadriceps excursion was also studied under fluoroscopy in six volunteers throughout the range of movement.
The quadriceps release improved the range of motion in all patients; at least 135 degrees of flexion were obtained. The improvements were more dramatic in patients who had previous surgeries. The average of improvement in knee flexion after the release was 36 degrees. The presence of osteophytes or gross deformity did not influence the degree of improvement. The fluoroscopy study has shown that the average excursion of quadriceps muscle from 0 to 145 degrees is 7 cm. The excursion per degree varies throughout the range of motion; it is more per degree near full flexion and extension than around 90 degrees of flexion.
The limited excursion of the quadriceps muscle is the main limiting factor to full knee flexion. Other pathological changes such as osteophytes, surface pathology, posterior capsule and the cruciate ligaments play very limited roles.
The aim of the study was to determine the precision of conventional versus computer-assisted techniques for positioning the acetabular component in total hip arthroplasty (THA).
Malposition of the acetabular component during THA increases the occurrence of impingement, reduces range of motion, and increases the risk of dislocation and long-term wear. To prevent malpositioned hip implants, an increasing number of computer assisted surgery systems have been described, but their accuracy is not well established.
Using a lateral approach, 150 cups were placed by 10 different surgeons in 10 identical plastic pelvis models. Only the immediate operating field was visible. Pre-operative planning was performed with a computerised tomography scan. Fifty cups were placed free hand, 50 others with the standard cup positioner, and the remaining 50 cups using computer-assisted orthopaedic surgery (Medivision). The accuracy of cup abduction and anteversion was assessed with an electromagnetic system (Fastrak™).
Using conventional techniques, free hand placement revealed a mean precision of cup anteversion and abduction of 10° [range 5.5 to 14] and 3.5° [2.5 to 5] respectively. With the cup positioner, these angles measured 8° [5 to 10.5] and 4° [3 to 5.5] respectively, and using the computer assisted method, the mean cup anteversion precision was 1.5° [1 to 2] and mean cup abduction measured 2.5° [2 to 3.5].
Computer assisted cup placement is a very accurate and reproducible technique during THA. It is clearly more precise than either of the two traditional methods of cup positioning, even for well-trained surgeons.
Absorbable cement restrictors have been in use over the last few years. They have been shown to be as effective as the standard non-absorbable cement restrictors in achieving cement pressurisation and stopping distal cement migration in in vitro studies. The aim of this study is to compare in vivo, the effectiveness of absorbable with non-absorbable cement restrictors.
One hundred and thirty-six consecutive patients who had total hip replacement performed using charnley cemented femoral prosthesis were selected and randomly divided in to two groups pre operatively. One group received Hardinge TM non-absorbable cement restrictor and the second group received Biostop TM absorbable cement restrictor. Type of the prosthesis, the surgical approach, the time from start of mixing of the cement to insertion of the cement (measure of viscosity of the cement), the cementing technique and the distance at which the cement restrictor was inserted were noted intraoperatively, the canal diameter was measured from the preoperative AP radiograph of the hip. The distance at which the cement restrictor was inserted was measured on the AP radiograph of the hip taken twenty-four hours postoperatively. All the above factors were statistically assessed as to their effect in the distal migration on cement restrictor using multiple regression analysis.
There was no statistical difference between the two types of cement restrictors (P= 0.44). Surgeon, Surgical approach, femoral canal diameter P> 0.2 cementing technique P> 0.1 and Cement viscosity P= 0.082 had no effect on the degree of distal migration of the cement.
In conclusion Biostop TM absorbable cement restrictor is as effective as Hardinge TM non-absorbable cement restrictor. We could not show any relationship between femoral canal diameter cementing technique and cement viscosity and distal cement migration which leads us to conclude that in the presence of adequate cement restriction these factors have little effect in distal migration of cement mantle.
Revision total hip arthroplasty, with retention of well fixed femoral and acetabular components and exchange of modular femoral heads and acetabular liners, is seeing increasing usage, primarily for the treatment of osteolysis or recurrent dislocations. The purpose of this study was to determine the dislocation rate after this procedure.
From January 1993 to December 2000, 54 patients underwent isolated head and liner exchange performed by two surgeons. These patients have been followed bi-annually with clinical and radiographic evaulation. There were 36 males and 18 females. Diagnoses at the time of revision surgery were recurrent dislocations in 27 and osteolysis in 27.
The overall dislocation rate was 11% (6/54). In the 49 non-constrained revisions, a 28 mm diameter femoral head was used in 27 and a 32 mm head in 22. At the time of revision, 60% of the femoral heads were lengthened, 40% were increased in diameter, and 25% were increased in both dimensions. Hooded or later-alised liners were used in 55% of the revisions. Operative stability was documented in all operative notes, and in 85% Ranawat’s sign was used to determine liner placement based on relative component version. The dislocation rate in the non-constrained revisions was 8% (4/49). Two out of five constrained revisions, performed for recurrent dislocations, subsequently dislocated. In this study isolated head and liner revision had a comparable dislocation rate to full revision total hip arthroplasty.
Fluid pressure generated in the hip during activity has been implicated in component loosening. Animal studies show both the adverse effect of direct pressure on osteocytes and the resorption of bone subjected to cyclic loads. Pressure fluctuation measured in contained pelvic osteolytic lesions during manipulation of the hip at revision surgery suggests cyclic pressure may have a direct effect on bone resorption leading to pelvic osteolysis.
To determine the cause of pressure fluctuation in pelvic structures supporting a hip implant, we conducted an experimental and numerical analysis of relative motion at modular interfaces of acetabular cups as load was applied and removed.
We showed that for polyethylene bearing inserts supported primarily at the rim, the application of cyclic load caused cyclic motion between the insert and the inside surface of the acetabular shell. In a fluid environment, this motion can generate cyclic pressure pulses that may be applied to bone directly through the holes in the shell provided for screw fixation.
We conclude that motion at modular interfaces of acetabular components may contribute to pelvic osteolysis. Our hypothesis is that the motion of a bearing liner under cyclic load can produce fluctuating pressure pulses that are applied to bone directly through screw holes. In addition, the pulses may aid the transport of polyethylene wear debris particles into fixation interfaces. It is possible that lytic lesions previously associated with backside wear of the liner may be related to pumping of joint fluid by the liner.
We report a three year Medical Devices Agency and Local Ethical Committee approved prospective study for a new tri-tapered polished cannulated cemented femoral component. Our stem was implanted in 53 primary total hip replacements. Eleven male patients (11 hips) and 39 female patients (39 hips). The mean age at surgery was 73 (range 65 to 84). The mean weight was 71.76 kg (range 49.3 kg to 94.6 kg) with a mean BMI of 28 (range 20.20 to 40.26). All patients had a pre operative diagnosis of osteoarthritis. All the hips were implanted via the anterolateral approach. Twenty-six (51%) hips were implanted by a single consultant and 24 (49%) were implanted by six different registrars. Pre-operative and sequential post-operative clinical and radiological evaluations were undertaken.
The mean pre-operative Oxford hip score was 47 points.which declined 19 points at three years. Radiological analysis, using the Johnston criteria, did not reveal any untoward features. Prosthetic stem migration was measured using a technique developed in our unit and validated as accurate to 0.61 mm; as previously reported. Stem migration measured averaged 1.38 mm (n=52; sd ±1.38) 6 months post implantation. This progressed to 1.71 mm (n=50; SD=1.18) at one year; 1.61mm (n=48; sd ±1.17) at 2 years. and 1.55 mm (n=28; SD 1.13). At 3 years average stem migration for hips implanted by the registrar group and the consultant group was not sig-nificantly different (p=0.2048) and the migration curve, against time was similar for both groups.
Our study has demonstrated initial component migration, comparable to that of other polished tapered cemented stem designs. The improvement in Oxford hip score parallels other reported series and no adverse radiological signs have been observed. Long-term surveillance of our cohort will provide further data to compare the new design with substantial equivalents. More sophisticated studies, such as RSA analysis would provide further data on early femoral component migration.
Prevention of joint dislocation after total hip arthroplasty (THA) is important to keep suitable relationships between surgeons and patients. Capsule has an essential role for stability of joint, especially in hip. Reserving a part of capsule in THA can increase stability. We examined the effect of partial capsulotomy in hip joint for prevention of dislocations after THA.
In 178 primary THA for osteoarthritis, partial capsulotomy were performed in 92 cases and generous capsulectomy in 86 cases from 1993 to 2001. Age, gender, pre-operative complications of both groups were matched. All THA were performed from a posterior approach, and in case of partial capsulotomy, anterior one third of hip joint capsule was reserved before placing acetabular component. Posterior capsulorrhaphy was not performed.
No hip dislocations have been seen in partial capsulotomy cases, and four posterior dislocations following THA were observed in general capsulectomy cases during one to nine year follow up.
Soft tissue imbalance of THA is most at risk for dislocation. The present study showed a satisfying result of partial capsulotomy for prevention of THA dislocation. Residual hip joint capsule can increase joint stability and can resist to dislocation after THA in osteoarthritis.
The aim of this study is to compare the clinical results of the Pin-Sleeve System (AI Wiring System; AIWS) with the Dall-Miles Cable Grip System (DMCGS) for reattachment after dissection of the greater trochanter in hip arthroplasty.
The DMCGS was used in 33 cases 35 hips from 1994 to 1998 and AIWS in 40 cases 42 hips from 1998 to 2001. The age at operation was 61.3 years (24 to 85 years) in the DMCGS group and 67 years (24 to 86 years) in the AIWS group. The postoperative follow-up period was 24 months (4 months to 54 months) in the DMCGS group and 30 months (11 months to 42 months) in the AIWS group.
Bone union failure of the great trochanter occurred in the DMCGS group eight hips (22.9%) and AIWS group five hips (11.9%). The DMCGS group four hips (11.4%) had broken cables, while not even one case of the AIWS group had them (p< 0.05). Fragments from the cable were found in the DMCGS group seven hips (20%) and AIWS group two hips (4.8%). Bone resorption around the cable, grip or sleeve occurred in the DMCGS group 19 hips (54.3%) and AIWS group five hips (11.9%) (p< 0.05). Clinically, the DMCGS group 13 hips (37.1%) and AIWS group seven hips (16.7%) had dysphoria at the greater trochanter; the DMCGS group 17 hips (48.6%) and AIWS group eight hips (19%) had pain at the greater trochanter in the recumbent position with the affected side down (p< 0.05); the DMCGS group 13 hips (37.1%) and AIWS group six hips (14.3%) had pain on exertion.
The AIWS is considered to be a useful implant for reattachment of the greater trochanter compared with the DMCGS.
The most common reason for possible complications after total hip replacement (THR) surgery is improper positioning of the implant components within the hip joint. Systems for computer assisted planning and navigation during THR have been developed. However, these established modules focus on the acetabular implant component only; disrespecting the fact that proper implant functioning relies upon correct placement of both components relative to each other. Therefore, we developed an extension to the existing CT-based SurgiGATE-Prosthetics system (Medivision, Oberdorf, Switzerland) for planning and placing of the acetabular component to give the surgeon a tool, which can help him/her to also plan and insert the femoral implant.
Preoperatively, the appropriate size and position as well as the orientation of both implants components were planned. Following navigated cup placement a dynamic reference base (DRB) was fixed to the thighbone and the registration procedure was executed. For the preparation of the femoral cavity a modular PPF rasp system (Biomet-Merck, Darmstadt, Germany) was developed. All surgical action was visualised graphically within the patient’s image data. In addition, the surgeon was provided with real-time information about the depth of tool insertion, antetorsion angle, varus/valgus deviation, and the postoperative change in leg length and lateralisation of the hip joint.
After extensive validation and accuracy analyses performed on plastic models the presented system was used during one operation. An extended clinical study is currently being started.
We expect that the developed application will help the surgeon to better plan the appropriate size and position of the both parts of a hip endoprosthesis and will supply intraoperative feedback of the position of the surgical instruments relative to the patients’ anatomy and to the preoperative plan. Safer and more accurate placement of the implants components during free-hand THR surgery may be expected from this technology.
The actual data about prevalence of knee osteoarthritis, the concurrent increasing of mean age and therefore the high social costs for the care of this pathology, make particularly important to do the correct choice in knee artroprosthesis. In this work we mean compare three different type of knee prostheses implanted in our institute. We have evaluated 120 patients (98 females, 22 males) treated with TKR in I° Orthopaedic Division of Istituto Ortopedico “Gaetano Pini” – Milano. All patients were affected by primary knee osteoarthritis of high degree and 3 groups were made due to the type of prosthesis implanted.
Our evaluation protocol includes: 1. Local objective examination and evaluation of Range of Motion (R.O.M.); 2. Subjective functional questionnaire (Lequesne Index modified for knee osteoarthritis); 3. Stabilometric evaluation for Proprioceptive knee structures (KAT-2000 Breg Inc. USA); 4. Standard X-Ray, both in AP and lateral planes, with patient in standing position.
The X-Ray controls showed no early mobilisations or malfitting of all implants. In consideration of the short follow-up period we have to do a continuous monitoring for at least 5 years to express a definitive evaluation of implant stability; significatively better results regarding the post-op R.O.M. and subjective results with Lequesne Index have been obtained with the use of mobile plate prosthesis.
The first results have pointed out better results in the use of a fully mobile plate prosthesis, compared with the other results using rotating and fixed plate prostheses.
In our opinion this is obtained through the research of a better reproduction of human anatomy and trying to respect the common kinematics of knee, which has to be the future objective in design and technical development of knee arthroplasty.
Rotational mal-alignment of the patella-femoral interface will result in increased wear. Highly cross-linked polyethylene will decrease wear even if mal-aligned.
A biomechanical model based on high load and flexion was used to measure wear of rotationally aligned and mal-aligned all-polyethylene patellae. The components were articulated against “aligned” and “mal-aligned” (60 internally rotated) femoral components. The patella were subjected to a constant 2224 N force and the femoral components rotated from 600 to 1200 at 1.33 Hz. Patellae of identical geometry made of conventional UHMWPE and highly crosslinked UHMWPE were tested to 1 000 000 cycles. Wear was determined by gravimetric measurement relative to cemented soak controls.
Conventional UHMWPE: All samples demonstrated damage (burnishing and scratching) of the articulating surfaces. There was a significant increase in wear (p< .05) in the mal-aligned patella.
Highly cross-linked patellae: All components fractured in the mal-aligned construct (gamma irradiated remelted n=6, gamma irradiated and annealed n=2). Failure first occurred at the cement interface then at the posts.
Correct femoral rotation is important during TKA. The intertrochlear line, tibial cut, epicondylar axis and posterior condyles are helpful landmarks, but there is still eyeball control of rotation. It is clear from this study that rotational mal-alignment will result in increased polyethylene wear.
Highly cross-linked polyethylene has decreased wear in THA. Unfortunately, the decrease in ductility and toughness may make the use of these materials unsuitable for TKA. Based on this study model, patellar components would need to be redesigned if highly cross-linked polyethylene were to be applied.
The wear rate of conventional UHMWPE patellae is increased by rotational mal-alignment. Highly cross-linked components were a poor solution to problem. Use of highly cross-linked polyethylene resulted in component fracture.
Recently, highly cross-linked polyethylene has been highlighted in THAs which is thought to reduce wear. However, little is known about an accurate nature of cross-linked polyethylene particles and long term wear in vivo. One of the authors implanted all polyethylene cups irradiated by 100 Mrad in 1970s. Recently, we performed two revisions with this cup. In the present study, we extracted polyethylene particles and made direct wear measurements on retrieved cups.
Case one was revised for a stem fracture and acetabular loosening at 25 years postoperatively and case two for acetabular loosening at 27 years postoperatively. There was no osteolysis on X rays. We extracted polyethylene particles using a tiussue digestion and image analysis developed by Cambell and measured wear of retrieved cups using casting and 3D scanner developed by us.
Equivalent circle diameter (ECD) was 0.73 um, roundness was 0.69, aspect ratio (AR) was 1.4 and number of particles was 6.0 hundreds million/g wet tissue in case one. ECD was 0.57 um, roundness was 0.62, AR was 1.54 and number of particles was 5.8 hundreds million/g in case two. SEM showed that granule or globular shapes were abundant and fibril shapes were rare. Direct wear measurement showed concentric wear patterns were observed with very low linear wear (less than 0.03 mm).
Cross-linked polyethylene particles were less, a little smaller and much rounder in compared with our previous result of conventional polyethylene in peri-implant tissue. No unidirectional and significant amount of wear was observed in retrieved cups even after over 25 years.
Orthopedic surgeons are taught to remove the under surface of the patella in accordance with the thickness of polyethylene used to replace an equivalent amount of bone. Inability, however, to obtain a symmetrical removal of bone can lead to subluxation, increased tension producing pain, and affect range of motion. A convenient and fast way to recognise this asymmetry and remove an additional sliver of bone from the patella would be an advantage in creating a patella of even thickness.
Eight orthopedic surgeons were asked to evaluate 24 pre-cut patellar specimens with varying asymmetric thicknesses in a bag without visualisation. By feeling the patella between the thumb and forefinger, they were instructed to identify the thickest portion of the patella as well as to determine the difference in thickness between the thinnest and thickest sides. Two trials were conducted with each orthopedic surgeon consecutively.
Orthopedic surgeons were able to determine through proprioception the thickest one-half of the patella 91% of the time. This did correlate with experience in total knee arthroplasty. They were able to differentiate a 1 mm difference in patellar asymmetry 36% of the time, a 2 mm difference 61% of the time, and a 3 mm difference 81% of the time.
Orthopedic surgeons can identify an asymmetrically cut patella by assessing thickness of the patella between their thumb and forefinger the majority of the time. By doing this technique, inadvertent asymmetrically thick patellas at the time of total joint arthroplasty can be min-imised. This technique should be incorporated into the standard regimen of performing total knee arthroplasties.
Common problems following total knee arthroplasty include tibial component malpositioning, ligament imbalance, and clinical and subclinical fat embolism associated with intramedullary alignment guides. Tibial component malaligment can lead to component loosening. Ligament imbalance can lead to dysfunction and the need for revision. Fat embolism had been shown to occur in 46% of unilateral and 65% of bilateral total knee arthroplasty patients with neurological sequelae in 2 and 4% of patients respectively (Kim YH, J. Arth. 1999). All three of these common problems can be addressed with the use of surgical navigation.
Instruments designed for the Genesis II total knee arthroplasty (Smith-Nephew, Memphis, TN) are tracked optically using the ION virtual fluoroscopy surgical navigation system (Medtronics SNT, Louisville, CO). A software system specifically designed for TKR navigation is employed. Following exposure, reference frames are attached to the femur and tibia and fluoroscopic images of the knee are obtained. Hip and Ankle centres can be determined either kinematically or with images. Proper alignment and component rotation is determined using navigation without intramedullary alignment guides. Proper implant sizing is determined before the cuts are made by superimposing images of the proposed implants into the fluoroscopic images of the knee. Motion and ligament integrity can be quantified kinematically. The system was used to perform total knee arthroplasty on 14 cadavers. Post-operative alignment was measured radiographically.
As compared to the mechanical axis measured radiographically, the coronal femoral alignment measured 0.03 degrees of valgus (95% confidence:−1.81 to 1.88 degrees). Coronal tibial aligment measured 0.88 degrees of valgus (95% confidence: −2.17 to 0.41 degrees). Sagittal tibial aligment measured 1.81 degrees of posterior slope (95% confidence: −0.14 to 3.76 degrees)
The use of surgical navigation for TKA results in appropriately aligned implants. Surgical navigation has the potential to improve many of the most common problems encountered during and following total knee arthroplasty including component malaligment and malsizing, malrotation, ligament imbalance, and fat embolism.
Correct placement of the total elbow endoprosthesis is a critical factor for the long-term success of an artificial joint. Correct restoration of the centre of rotation is essential for optimal outcome. To evaluate whether surgical navigation has the potential to improve accuracy during Total Elbow Arthroplasty (TEA), an existing CAS system was applied on one plastic model and three patients.
The spine module of the SurgiGATE™ navigation system (Medivision, Oberdorf, Switzerland) was used. To apply it during TEA, a standard 3.5-mm drill guide was instrumented with infrared LEDs and calibrated. A dynamic reference base (DRB) was developed. Its base consisted of an X-shaped, scissors-like construct that could be clamped rigidly onto the distal humerus after exposure. On a plastic model, the DRB design was evaluated, and three landmarks suitable for intraoperative matching were identified. Subsequently, the Spine system was applied during three TEA surgeries. For the first surgery no pre-operative CT scan was acquired, but the design of the DRB, its camera visibility, and the accessibility of the landmarks were verified. For the other cases, the elbows were CT-scanned preoperatively. Planning consisted of 3-D segmentation as well as the definition of matching landmarks and a trajectory representing the position of a Steinmann pin, with which the humeral implant position is defined. Intraoperatively, the DRB was fixated, and matching was performed. Using the navigation system, the drill guide could then be aligned with the planned trajectory.
For the second patient, no accurate matching was achieved, hence surgery was completed conventionally. The last patient could be registered precisely, and the Steinmann pin was placed as planned.
Preliminary results show that CT-based navigation can be applied during TEA. Given a positive output of an ongoing clinical study, the development of a special TEA navigation system is planned.
Acetabular component malposition is the cause of half of all cases of recurrent hip dislocation. Intraoperative xrays after component insertion are helpful, yet it is certainly more useful to know the exact component position before final component insertion. The current study reviews results of acetabular component positioning using surgical navigation.
A prospective study of acetabular component positioning using surgical navigation was conducted in 22 hips of 21 patients. The technique involves insertion of a dynamic reference frame onto the pelvis during the surgical exposure and the acquisition of AP fluoroscopic views of each hip. Using the Fluoronav software and the ION surgical navigation system (Medtronics, Louisville, Colorado) a virtual horizontal line was then drawn between the teardrops. Acetabular component abduction was then aimed for 41 degrees. Component abduction was measured intra-operatively during component insertion by measuring the angle between the acetabular insertion handle and the virtual horizontal line between the teardrops. Post-operative xrays were analyzed for acetabular component abduction angle.
Using surgical navigation and aiming for 41 degrees of abduction resulted in post-operative cup positions averaging 40.8 degrees (range 37 to 44 degrees). These results show dramatically improved accuracy as compared to 85 acetabular component inserted without navigation showing a mean abduction of 42.8 degrees but with a range of 25 to 59 degrees. Frame placement and image acquisition required about 10 minutes. All intra-operative imaging after component insertion in complex cases was unnecessary. Having the dynamic reference frame in place also allowed assessment of pelvic position during surgery. Pelvic orientation varied greatly between patients on the operating table from about 12 degrees abducted to 12 degrees adducted. Further, pelvic orientation varied during surgery.
Surgical navigation allows extremely accurate positioning of the acetabular component at the time of total hip replacement surgery with an accuracy far greater than any study of acetabular component positioning reported in the literature. The pelvis is typically not orthogonal to the operating table during total hip arthroplasty and its position varies widely between patients and in the same patient during the procedure. Since acetabular component malposition represents the cause of half of all cases of recurrent dislocation, surgical navigation has been shown to directly address and potentially eliminate the problem of acetabular component malposition.
It is well established in the literature that the tribological properties of sliding metallic and ultra-high molecular weight polyethylene (UHMWPE) counterfaces are a major contributor to accelerate wear rates that contribute to osteolysis. The majority of the research over the years has been on improving the UHMWPE properties through manufacture and secondary processing of the polymer. Little attention has been directed towards the optimisation of the Chromium Cobalt Molybdenum (CrCoMo) surface finish.
The focus of this research has been on the highly polished CrCoMo metallic surface. A new surface finishing technique was applied to CrCoMo femoral knee prosthetic implants. The surface finish of our finished implants was compared to that finished by traditional mechanical polishing techniques. A representative number of polished CrCoMo knee femoral components were compared under the following topics; tribological, topographical and the extent of processing containments present.
It was found that traditional mechanically polished parts contained a significant amount of embedded polishing compounds (Al2O3), coarse interdendritic (M7C3) and fine (M23C6) carbide elements. Both the polishing containments and carbide elements stand proud of the articulating surface and thus act as micro cutting tools to accelerate UHMWPE wear. The new polishing technique completely eliminated hard carbide particles and embedded polishing compound media. Consequently, the samples prepared using the new polishing technique produced lower UHMWPE wear debris and improved wear patterns to that of the traditionally polished samples. Additionally, all sub-micron scratching was removed from the surface of the samples.
This polishing technique for CrCoMo prosthesis represents a milestone in CrCoMo surface finishing and will significantly reduce the UHMWPE wear debris generated and consequently increasing prosthesis longetivity.
Today’s major challenge for total hip arthroplasty is to minimise wear and osteolysis in our younger and more active patients. Alumina ceramic bearings have known superior wear resistance and lubrication and do not carry a risk of ion release. Utilising new improved alumina ceramic materials and implant design 514 hips were implanted in a multicentre US IDE prospective and randomised study. The study compared alumina-on-alumina ceramic bearings to a cobalt chrome-on-polyethylene bearing.
All patients received the same press-fit hydroxylapatite coated femoral stem while two-thirds (349 hips) received alumina ceramic bearings and one-third (165 hips) received the cobalt chrome on polyethylene bearing. All patients suffered from non-inflammatory arthritis and were young and active with an average age of 53 years.
At a follow-up of 24–60 months (mean 39.8 months) there was no significant difference in clinical performance between the patient cohorts.
Utilising a new implant design and improved alumina ceramic materials, 514 hips were implanted in a US IDE prospective, randomised study. All patients received the same press-fit hydroxylapatite (HA) coated femoral stem. Two-thirds (349 hips) received alumina ceramic bearings, and one-third (165 hips) received CoCr heads on polyethylene liners. The alumina group was further divided. Approximately one-half (172 hips – System I) received a porous-coated titanium shell and an alumina insert, and one-half (177 hips – System II ) received a HA-coated, arc-deposited titanium shell and an alumina insert. System III (the control) consisted of a porous-coated titanium shell and a polyethylene insert. External geometry of all shells was identical.
An independent orthopaedic surgeon who did not participate in the study reviewed all radiographs. At latest follow-up, (minimum 2 years; range 2-4 years), differences were noted in the developmental pattern of the radiolucent line around the acetabular component. Radiolucent lines were most often noted with System I and System III (porous acetabular shells) in De Lee and Charnley Zone 3 and were absent in System II (arc-deposited titanium with HA) (p=0.001). Other standard radiographic parameters evaluated were found to be comparable, with one exception: In 10 cases in the control group, the development of a small erosive lesion (scalloping) in femoral Gruen Zone 8 was observed on the lateral film. This compares to two cases in System I, and no cases in System II (p=0.001).
Dislocation rates were comparable for all three Systems. Seven acetabular components were revised: one in System I, three in System II and System III. The two revisions for aseptic loosening were both in the control group.
This study measured polyethylene wear and correlated it with design features such as tibiofemoral conformity and contact areas.
Two femoral component designs were tested in a knee wear simulator. The femoral condyles of design A were flat-on-flat in the coronal plane, while those of design B were curved-on-curved. These femoral components were tested with two inserts. Insert PLI had a posterior lip, while insert C had a more curved sagital geometry, to improve stability in the anteroposterior direction. All components were tested for up to five million cycles in bovine serum lubricant. Triaxial forces were monitored to ensure that loading conditions were similar in all combinations tested. Gravimetric wear measurements were made at 500 000 cycle intervals. Contact stresses were measured using pressure sensitive film and dynamic finite element analysis.
Contact stresses were 22% higher for inserts tested with design A compared to design B. Sliding distance, sliding velocity, and patterns of crossing motion were found to be comparable between the two femoral designs. Inserts tested with design A wore significantly more (mean 10.9 mg/million cycles) than design B (mean 5.71 mg/million cycles, p < 0.001). No appreciable differences were found between wear rates of insert PLI and insert C.
Component design can have a significant impact on polyethylene wear rate. Careful control of kinematic and loading conditions allowed for comparison between specific design features. Increase in tibio-femoral contact area led to reduction of contact stresses, which was reflected in the reduced wear rate.
The novel horseshoe shaped cup was designed by the senior authors to minimise the resection of healthy bone in total hip arthroplasty. It replaces the cartilage and underlying sub-chondral bone of the acetabulum socket with a cup that is designed to flex in harmony with the surrounding bony structure.
Fifty female patients with a displaced, subcapital, femoral neck fractures were chosen for the study. In half of the group of patients, the composite support shell was coated with HA, with the other half remaining uncoated. Clinical and radiological assessments were undertaken regularly for five years.
To date 20 patients have died and 13 have withdrawn from the study due to poor medical health unrelated to the study. Charnley modified Merle d’Aubigne score at five years was as good as the preoperative score with 80% of patients having full range of movement, no pain and walking unaided.
Radiographic results showed no evidence of loosening of HA coated cups, in contrast to non HA coated cups which migrated significantly in 80% of cases. Four patients with loose non HA coated cups underwent revision surgery.
This trial has demonstrated success at 5 years with the HA coated Cambridge Acetabular Cup. Cups from which HA coating has been removed have migrated significantly in 80% of cases. There is an advantage of the HA fixation which will be taken into account before wider clinical usage is advocated.
The site of initiation of failure of a cemented femoral component is usually the prosthesis-cement interface. Strengthening this interface with porosity reduction may improve survivorship. Cement pores which propagate crack formation can be reduced by vacuum mixing or centrifugation, but this does not effect interface porosity.
Utilising simulated stems cemented into a “Sawbones” femur in a manner replicating surgery, we determined the effect of stem warming on various parameters. Maximum temperature and time of polymerisation, mechanical strength, porosity reduction and pore distribution in the cement mantle were measured with stems at room temperature (RT), 37, 44, and 50 degrees Celcius. Mechanical testing included initial “push-out” tests, tests after agiing in 37 degrees Celcius saline for two weeks,and fatigue testing (3 HZ at 90% initial failure load). Porosity distribution was measured by the percentage area of pores on the interface surfaces and the transverse plane.
Polymerisation time decreased as the stems were heated. The time decreased from 8.1 minutes at RT to 5.9 minutes at 50 degrees Celcius. The maximum temperature in the cement mantle rose from 50.2 to 56.4 degrees Celcius comparing stems at RT to those at 37 degrees Celcius, and did not elevate further as stems were preheated to 44 and 50 degrees Celcius. Similarly, static and fatigue interface strength improved by preheating stems, but no significant gain compared to RT stems was realised by heating above 37 degrees Celcius.
A dramatic reduction in porosity at the prosthesis-cement region was found with the heated stems, with no additional benefit to heating beyond 37 degrees Celcius. An increase in porosity at the cement-bone interface was noted as stems were heated. This may be due to the direction of polymerisation shrinkage in the cement mantle as influenced by stem temperature.
Although hydroxyapatite (HA) coating is known to enhance fixation in THR, its role in the fixation of Total Knee Replacements is less well appreciated. This study was performed to assess the medium-term results of an HA-coated TKR.
Between August 1992 and 1998 all patients requiring a primary TKR were treated with a hydroxyapatite-coated, PCL-retaining prosthesis implanted by the senior author. The HA coating used was 70 microns thick with 75% crystallinity and 20% porosity. It is deposited on a beaded heat-sintered surface. A combined Hospital for Special Surgery and Knee Society Score was recorded pre-operatively and at three, six, 12, 24 and 60 months post-operatively. Fluoroscopically-controlled interface views were performed on the first 161 knees immediately post-operatively and repeated 24 months postoperatively.
Six hundred and ninety two patients (Male:Female 335:357) with a mean age of 68 years (31–88 years) underwent 1 000 TKR mainly for OA (93%) and inflammatory arthropathies (RA 3%, psoriasis 1%). The mean follow up was 75 months (40–115). There were 461 unilateral (R:L 256:205) and 539 bilateral replacements (462 simultaneous and 77 staged).
The pre-operative knee score was 95/200, ROM 6–115 degrees and at latest review was 182/200, ROM 1–113 degrees.
Forty four patients have died (mean age 73 years, range 54 to 88). There have been 14 deep infections (1.4%), 22 proven pulmonary emboli (2.2%) and five periprosthetic fractures (0.5%). Six revisions have been performed. Visible gaps between bone and implant were present in 91% of femora and 58% of tibiae initially and in 6% of femora and 8% of tibiae at two years on interface views. There have been no cases of clinical loosening.
Currently, this study comprises the largest known series of HA-coated total knee replacements. These results demonstrate that HA appears to enhance fixation of uncemented knee prostheses which maintain good clinical outcomes.
Polyethylene contact stresses have been shown to correlate with wear in total hip arthroplasty (THA). Several liner designs have been introduced in an attempt to increase stability or reduce impingement and increase range of motion. This study analyzed the effect of liner design on range of motion (ROM) and PE contact stresses in a finite element model (FEM).
FEMs of four liner designs were generated: Generic was modelled as a simple hemisphere, Chamfer had a wide chamfer on the inner edge of the liner to increase ROM, Highwall had an extended lip to increase stability, and Anteverted created a 20° anteversion with lat-eralisation of the centre of rotation. With the liners in varying positions of abduction and anteversion, physiologic loads were applied through the femoral head. Hip ROM was measured by rotating the head and neck in different directions until prosthetic impingement.
Significant differences in ROM were seen relative to the Generic liner. Chamfer increased ROM by mean 16%. Highwall reduced ROM by mean 12%. Anteverted increased flexion by 17% but decreased extension, abduction, and external rotation. Contact stresses were also significantly affected by liner design and acetabular orientation. Overall for the same acetabular position, contact stresses were higher for Chamfer and lower for Highwall and Anteverted.
These results underline the complex interaction between cup design, hip stability, range of motion and contact stresses. Design features that increase stability tend to reduce contact stresses and ROM, while those features that increase ROM, tend to increase contact stresses. This data can help the surgeon match liner design to specific patient requirements.
The objective of this present study was to determine the in vivo kinematic patterns for subjects implanted with a patellofemoral arthroplasty (PFA).
Twenty subjects, all having a PFA, were studied (< 2 years post-op) under fluoroscopic surveillance to determine patellofemoral contact positions, sagittal plane, and medial/lateral translation using a skyline view.
The patellofemoral contact patterns for each subject having a PFA was highly variable, 11.9 mm of translation. The average amount of patella rotation during the full flexion cycle was 26.3 degrees, while one subject experienced 48.6 degrees. The average amount of medial/lateral translation was 3.8 mm (5 > 5 mm). Five subjects experienced grater than 5 mm of motion.
This was the first study to ever determine the in vivo kinematics for subjects having a PFA and the in vivo medial/lateral translation patterns of the patellofemoral joint. Subjects in this study experienced high variability and some abnormal rotational patterns. Most of the subjects who underwent PFA in this study had a previous history of subluxed or dislocated patella which affects the normal patella tracking, especially regarding tilting and translation. This tracking may also be directly affected by patellofemoral conformity, a consequence of femoral implant design. Finally, after PFA the patello-tibial tilt angle is influenced by the anteroposterior positioning of the femoral component.
The results of this very first in vivo kinematic study may play an important role, not only for design consideration of patellofemoral replacement but also for surgical technique in order to obtain optimal implant positioning.
The objective of the present study was to analyse kinematics of subjects having a UKA during stance phase of gait, where the ACL was intact at the time of the operative procedure.
Femorotibial contact positions for nineteen subjects (15 medial UKA (MUA); 14 lateral UKA (LUA); HSS > 90, post-op > 3 yrs) were analysed using video fluoroscopy.
During stance-phase of gait, on average, subjects having a medial UKA experienced 0.8 mm of anterior motion (7.7 to – 2.3 mm), while subjects having a lateral UKA experienced −0.4 mm (0.9 to – 2.1 mm) of posterior femoral rollback (PFR). Eight of 15 subjects having a medial UKA and two out of four lateral UKA experienced PFR. Eight of 15 subjects having a medial UKA experienced normal axial rotation (average = 0.9 degrees) and one out of four subjects having a lateral UKA experienced normal axial rotation (average = −6.0 degrees).
High variability in the kinematic data for subjects experiencing an anterior slide and opposite axial rotation suggests that these subjects had an ACL that was not functioning properly and was unable to provide an anterior constraint force with the necessary magnitude to thrust the femur in the anterior direction at full extension. Progressive laxity of the ACL may occur over time, and at least in part, lead to premature polyethylene wear occasionally seen in UKA. Our results support the findings of other studies that the ACL plays a significant role in maintaining satisfactory knee kinematics, which may also, in part, contribute to UKA longevity.
Improved cement technique by interposing less than two layers of hydroxyapatite (HA) granules between bone and bone cement at the cementing (Interface Bio-active Bone Cement : IBBC) have been performed in total knee arthroplasty (TKA) since 1987.
We performed IBBC technique in 153 knees (130 patients) in TKA from 1987 to 1993. One hundred and forty knees (120 patients) could be followed up clinically and radiologically. Follow up rate was 91.5%. A mean follow-up period was 9.5 years (6 to 13 years) after surgery. As a control, clinical results of TKA with conventional cementing (Non-IBBC) which were operated in 44 knees (44 patients) in 1986 were used.
In IBBC cases, radiolucent lines on the tibial components were seen 7.1%, 2.9%, 1.4%, 3.6%, 0%, 0% and 0% at Zone ‡T to ‡Z of the anteroposterior view, while in Non-IBBC cases, 40.9%, 13.6%, 9.1%, 27.3%, 11.4%, 4.5% and 13.6% at Zone ‡T to ‡Z, respectively. In IBBC cases peri-prosthetic osteolysis of the tibial components were seen in three knees (2.1%), while 29.5% in Non-IBBC cases. Aseptic loosening of the tibial component was only one case (0.7%) in IBBC cases, while 9.1% in Non-IBBC cases.
In IBBC, bone cement bound to HA mechanically immediately after surgery and HA granules bound to the bone physicochemically after bone ingrowth into the spaces around the HA granules. In Non-IBBC, spaces will appear between bone and bone cement due to osteoporosis and/or atrophy after long years. However, in IBBC, bone and bone cement will contact by interposing HA forever due to osteoconductive effect of HA.
In conclusion, the IBBC has significantly reduced the incidence of radiolucent lines and periprosthetic osteolysis in TKAs. IBBC is a method combining the advantage of cementless HA coating and bone cement.
We have used Interface Bioactive Bone Cement (IBBC) in all cases of total joint arthroplasties since 1987. The method is improved cement technique by interposing less than two layers of hydroxyapatite (HA) granules between bone and the polymethylmethacrylate (PMMA) bone cement. We report one patient who underwent revision surgery after total knee arthroplasty (TKA) using IBBC.
The patient is a woman aged 70 years at the time of revision surgery. Right TKA was performed with the diagnosis of rheumatoid arthritis. An alumina ceramic total knee prosthesis was inserted using IBBC. Pain and walking ability were once improved after the primary TKA. However, the gait disturbance recurred after the patient fell on the ground. Radiographic findings showed severe genu varum, but neither radiolucent lines around the components nor migration of the components were seen. This was revised with semiconstrained prosthesis for the purpose of improving lateral instability at 31 months after the primary TKA.
Avulsion of fibular attachment of collateral ligament was seen at the time of the revision surgery. As PMMA cement was strongly adhered to the bone, it was removed together with cancellous bone. Histologically, HA granules bound to the bone directly after bone ingrowth into the spaces around the HA granules. This is the reason we have described IBBC as a method having the both advantages of cementless HA coating and PMMA bone cement.
After the revision surgery, the walking ability was improved.
In conclusion, this case showed excellent characteristics of IBBC.
The objective of this present study is to conduct a comparative analysis of the kinematic data derived for all subjects having a TKA who were analysed over the past eight years at our laboratory.
Femorotibial contact positions for 705 subjects having either a fixed bearing PCR or PS TKA or mobile bearing TKA were analysed in three-dimensions using video fluoroscopy.
During a deep knee bend, all PS TKA types subjects experienced a medial pivot motion, averaging −3.8 of lateral condyle posterior femoral rollback (PFR), respectively. Subjects having a fixed bearing PCR TKA experienced only −0.7 mm of lateral condyle PFR and an anterior slide of 1.6 mm for the medial condyle. Twenty-nine percent of the PCR TKA analysed had a lateral pivot and 71% experienced a medial pivot. Subjects having a mobile bearing TKA experienced −2.8 mm of lateral condyle PFR and 0.4 mm of medial condyle anterior slide. Fifty-one percent of the moble bearing implants experienced a medial pivot and 43% experienced a lateral pivot. During gait, PS and PCR fixed bearing TKA types experienced similar kinematic patterns. Subjects having a mobile bearing TKA experienced minimal motion, probably due to the mobile bearing TKA having greater sagittal conformity and had the lowest standard deviation.
There was great variability in the data comparing various TKA designs. Subjects in this multicentre analysis predominantly experienced a medial pivot motion, although certain TKA designs did demonstrate a lateral pivot motion.
The use of exhaust suit systems is commonplace in arthroplasty surgery where isolation of the surgical team is desirable in an attempt to reduce the risk of infection transmission. Elevated carbon dioxide levels have been reported in the non-clinical setting with such systems the consequences of which can include fatigue, diapho-resis, nausea, headache and irritability.
The aim of our study was to determine the levels of carbon dioxide present within an exhaust suit system during hip arthroplasty and to compare these with the recommended occupational exposure limit levels published by the Health and Safety Executive (HSE).
Data was collected during ten primary hip replacements performed by the same surgeon whilst wearing the Stryker Steri-Shield Helmet Exhaust System. This is a self-contained unit with an integrated blower used in conjunction with a full-length gown. In addition the helmet was fitted with an air-sampling probe connected to a portable infrared CO2 monitor and also a temperature probe. Thus continuous monitoring of both CO2 and temperature level during surgery was possible.
The mean initial CO2 concentration in the helmet at the beginning of surgery was 3 000 parts per million (ppm) and the mean maximum CO2 level recorded was 13 000 ppm. The mean time the surgeon was within an exhaust suit to perform a primary hip replacement was 1 hr 54 mins and for 86% of this time period the CO2 level within the helmet exceeded the recommended level of 5 000 ppm as stipulated by the HSE.
In conclusion we have demonstrated significantly elevated CO2 levels within the Stryker Steri-shield Exhaust Suit System during hip surgery. Surgeons who use this system should be aware of this together with the physical symptoms that may result.
Initial fixation affects ingrowth of uncemented tibial components. Previous studies assessed initial fixation, however most used limited one-dimensional motion measurements. Therefore, a three-dimensional micro-motion and migration analysis was performed to compare initial fixation of four different tibial tray configurations: 1) Keeled component 2) Non-keeled component (post but no keel) 3) Keeled component with screws 4) Non-keeled component with screws.
Osteonics series 7 000 tibial trays (identical to Scorpio design) with and without standard keels were obtained. The 30 mm posts were left intact. The components were implanted without cement into twenty-four fresh-frozen cadaveric tibiae. Specimens were loaded through matched femoral components via two separate loading conditions: 1) sinusoidal medial load from 200 to 2 200 N at 0.5 Hz and 2) sinusoidal torsion load from −5 Nm to +5 Nm at 0.5 Hz with constant 1 200 N axial load. Motion data were collected from reference cubes and transducers rigidly attached to the trays, during 3 000 cycles of loading. Rigid-body mechanics were used to calculate the motion of a wire-frame computer model. Comparisons were made of micro-motion and migration magnitudes.
A keel did not significantly decrease micromotion or migration under medial or torsion loading compared to a post alone (p=1.04). The addition of four cancellous screws decreased motion (p< .05) regardless of the presence of a keel under medial loading. No significant differences were noted under torsional load for any tray configuration.
A keel did not enhance initial fixation compared to screws or a post alone. Screws enhanced fixation under axial offset loading in all constructs. Screw fixation did not affect motion under torsion loads perhaps due to the limited magnitude of torque transmitted across the unconstrained femoral-tibial articulation. Based on these data, initial fixation of uncemented tibial implants should include screw fixation to counter the effects of offset axial loads.
Large diameter metal on metal hip bearings have been shown to display exceptionally low wear in vivo. However, as these components are often cast, they may be heat treated to improve homogeneity, although it has been suggested that this may adversely affect wear. Therefore a hip simulator study was commissioned to investigate this further.
Multi-station hip simulator testing was carried out on 40 mm diameter high carbon cast cobalt chrome alloy components, all having similar radial clearances (~100mm), surface finishes (0.01mm Ra) and sphericity deviations (< 10mm). Three bearing couples were hot isostatic pressed (HIPed) and solution heat treated, generating a fine carbide structure, and three bearing couples were left as cast, creating a coarse carbide structure. All sockets were mounted in an MTS hip simulator, inclined at 35° to the horizontal, and subjected to standard walking conditions (2450 N max) using 25% bovine serum as a test lubricant. Wear was calculated gravimetrically using temperature controls.
Running-in wear was observed for both groups generating a similar combined head and cup mean wear rate of 2.3 mm3/106 cycles. The mean steady-state wear rate (SE) for the as cast and HIPed components was 0.38 (0.13) and 0.57 (0.11) mm3/106 cycles respectively showing no statistical difference (p > 0.2). Wear was generally higher for the cups than the heads.
These wear rates are two orders of magnitude lower than published wear rates of metal-UHMWP E under similar conditions and one order of magnitude lower than lightly crosslinked UHMWPE articulating against CoCrMo under the same conditions.
In this test, the effect of HIPing and solution heat treatment on metal-metal wear would therefore appear to be insignificant. This is in contrast to the published influences of both bearing diameter and bearing tolerances, i.e. sphericity and radial clearance on the wear of metal-metal hip joints.
Since acetabular osteolytic lesions following total hip arthroplasty (THA) may be asymptomatic until extensive bone loss occurs, early detection and monitoring the progression of these lesions is important. The purpose of this study was to use high resolution helical CT to determine the progression of the osteolytic lesions over time by comparing serial studies.
Fifty patients (Fifty-eight hips) with primary, cementless THA done between 1984–1996 were evaluated as part of an ongoing prospective study. These patients had a history of a high level of activity that was believed to place them at increased risk for accelerated polyethylene wear. The mean age was 51 yrs, 55% male:45% female. The average time from date of surgery to initial scan was 8.0 years (4.7–16.6). If an acetabular lytic lesion was identified, the patients were offered Alendronate for potential suppression of bone resorption with a repeat CT scan for follow-up. The area of the maximum size osteolytic lesions on axial images were measured on the initial scan and compared at the same level on the subsequent study.
The interval between scans averaged 15 months (10 – 27). Progression was noted on 87% hips. The mean initial area was 328 mm2 (40–1084) with the follow-up area of 386 mm2 (46–1344) with a mean of progression of 15.7%.
Once established, peri-acetabular lysis appears to be a slowly progressive, relentless process. Analysis of changes on serial CT, along with an assessment of the degree and location of lysis, provides an additional tool to evaluate the need for surgical intervention.
The benefit of mobile-bearing mechanism in total knee arthroplasty (TKA) has been controversial. The aim of this paper is to analyse the rotation of polyethylene (PE) and its effect on the range of motion (ROM) in mobile-bearing, posterior stabilised TKA (LPS-Flex™, Zimmer Co. Ltd.).
Thirty-four consecutive PS-Flex™ TKAs (28 patients) were analysed. Three tantalum markers were inserted in the PE and the tibia (one for medial side and two for lateral side; total six markers). The rotation of the PE and the tibia was analysed in fluoroscopically-controlled radiograph taken at one years in full extension, 90 degrees flexion and passive maximum flexion. The markers in the tibia were identifiable in 19 knees and the analysis was based on these knees.
The tibia rotated internally relative to the femur by 7.1± 5.2 degrees (mean ± SD, range −1 to 20 degrees). The amount of tibial rotation has no correlation to ROM. The rotation of the PE relative to the femur was unpredictable showing three knees with external rotation and four knees without rotation (Average; 4.0 ± 4.5 degrees internal rotation). The rotation of the PE on the tibia was 4.2± 5.2 degrees and seven knees (37 %) showed no rotation and 12 knees (63 %) showed less than 5 degrees rotation. There was a positive correlation between the amount of PE rotation on the tibia and ROM, which approached to statistical significance (p = 0.0684).
This study has demonstrated that the rotation of the PE on the tibial tray is generally small (< 5 degrees). Because not tibial internal rotation but PE movement on the tibia correlated to ROM, the essential benefit of the mobile-bearing mechanism could be to compensate the rotational mismatch between the components rather than to reproduce normal knee kinematics.
Outcomes for a RSP to treat either a previous operated shoulder (revision procedure) was compared to a primary RSP.
Twenty primary RSP (6M, 14F) for an irreparable rotator cuff tear (IRCT) with glenohumeral arthritis /anterior superior arch deficiency and 31 revision RSP (10M, 21F) (previous rotator or cuff surgery, hemi or total shoulder arthroplasty) were evaluated at an average of 24 months postoperatively. Mean age at the time of RSP was 72.3 for primaries 67.2 for revisions. Assessment with pre- and postoperatively SF-36, SST, ASES scores, physical exam, satisfaction surveys, and radiographs was performed.
Primary RSP improvements /Revision RSP improvements were: 9.4 sf-36 PCS/ 6.3 sf-36 PCS, 1.8 SST/ 1.6 SST,31.8ASES / 17.5ASES (p< 0.05),49.2 elevation/ 14.2 elevation (p< 0.05) and 57.8 external rotation/ 30 external rotation. 71.3% Excellent/good/. 56% Excellent/ good (p< 0.05), 21.4% satisfactory/ 33.3% satisfactory, 7.1% unsatisfactory outcome/ 9.5% unsatisfactory outcome. Complications only occurred in the revisions including component disassociation, glenoid loosening, recurrent instability, and infection
Primary RSP provides predictable improvements in pain and function with minimal complications. Revision RSP has a higher complication rate and improvements in pain and function are less reliable. Conventional shoulder arthroplasty for patients with IRCT with gle-nohumeral arthritis/anterior superior arch deficiency has resulted in adequate pain relief but functional improvement has not been predictable. Thus, the initial operative selection for these patients must consider the effect of a failed reconstructive attempt on patient outcomes.
The determination of the cause of prosthetic failures in total hip arthroplasties can be difficult. Pre-operative imaging, including plain x-rays, tri-phse bone scan and MRI imaging have not been able to discern septic from aspectic causation. White blood cell scans, once thought specific for infection when positive, has demonstrated positivity in”wear and debris” reactions. Labs including WBC, Sed Rate, CRP can be elevated in septic, as well as, aseptic failures. Although frozen section is reliable showing acute inflammation for infection, chronic active inflammation which often is seen with chronic infections, can also be seen in aspectic failures. Cultures are often falsely positive, but in chronic infection it may be associated with less than 80% retrieval.
Five cases of acetabular loosening associated with radiolucencies around a prosthesis were studied. These cases had rapid failures and were thought to be secondary to an oil residual left after processing of an in growth prosthesis. All patients had a radiolucent zone around the bone prosthetic intersurface. The patients had increasing pain on weight bearing and a positive bone scan. Frozen section at the time of surgery demonstrated chronic inflammation and was culture negative. The acetabular prosthesis and associated parts were placed immediately in 80% Etoh and Tris buffer. Combinations of confocal laser microscopy with live-dead stains, FISH Probes for Staph., or scanning electron microscopy was performed looking for biofilm.
All five of the prosthesis or related parts showed the presence of bacterial biofilm. One of these had cement covering the porous portion.
These results demonstrate our inability to discern aseptic from septic loosening in total hip arthroplasty by the current clinical means.
Twelve pairs of fresh-frozen, cadaveric femora were harvested. Each right femur was prepared for the cemented insertion of the femoral component of a total hip implant. Left femora served as matched intact controls. Following insertion of the implants, the distal tip of the stem was identified and an oblique osteotomy was made to represent a periprosthetic fracture. Proximally, plates were secured with cables and distally by bicortical screw fixation (c+s). The twelve pairs of femora were randomly divided into three groups: 1. Zimmer Cable-Ready System, 2. AO 4.5 mm broad, LC-DCP, with Wire Mounts and Double Luque Wires, 3. Dall-Miles Cable Grip System. Specimens were mounted and deforming forces were applied to test the biomechanical stiffness of the constructs. Following testing the plate-cable combinations, the proximal cables were removed and replaced with unicortical screws (s+s). Repeat testing was then performed as per the above protocol.
The stiffness of the constructs relative to intact bone decreased (p< 0.05) with fixation utilising cables plus screws (c+s) during four-point bending (69–77%) and offset rotational loading (61–64%). When testing unicor-tical plus bicortical screw fixation (s+s) in these modes, a similar effect was seen. There was no difference between plate systems (ANOVA, p> 0.05). Comparisons of stiffness between cable plus screw combination versus unicor-tical plus bicortical screw combination revealed that the latter method of fixation (s+s) was more rigid (p< 0.05).
Our study showed that the three plate-cable systems displayed similar biomechanical stiffness. In addition, when the cables were replaced proximally with unicortical screws, more rigid fixation was obtained in all but one plane of testing.
We conclude that the method of plate stabilisation by screws or cables is more significant than the type of plate used for periprosthetic fracture stabilisation.
Impacted morsellised donor bone is succesfully used to treat bone loss in revision total hip arthroplasties. After implantation new bone is formed in the donor bone. It is generally thought, but not proven, that the processing and storage at −80°C of the donor bone kills all cells. There is however general concern about viral, bacterial, and/or oncogenetic contamination with donor bone. Based on these considerations it is essential to know whether the donor bone does contain viable bone cells.
Fragmented biopsies from eleven femoral heads from our bone bank, which is processed according to the Musculo-skeletal Council of the American Associations of Tissue Banks (AATB) and the European Association of Musculo Skeletal Transaplantation (EAMST), were tested for their capacity to give rise to proliferating cells in vitro. This was repeated with five other femoral heads from the same bone bank after irradiation. Microscopic analysis of cell growth, aspect, and number was performed on the established cell cultures. DNA marker analysis of the cultured cells and freshly obtained buccal cells from the donor was done in order to verify the origin of the cultured cells.
All fragmented biopsies showed cell growth. Cell outgrowth time as well as cell number varied between donors, and was independent of the length of storage time at −80°C. No cell outgrowth was observed from irradiated bone. DNA marker analysis showed identical alleles for cultured cells from frozen bone and DNA from freshly obtained unfrozen buccal cells from the donor.
Biopsies from femoral heads from a bone bank according to the AATB and the EAMST contain living bone cells with growth capacity. It is unclear which role these vital cells play in the process of new bone formation in the donor bed, or in the risk of contamination.
Two hundred and seventeen consecutive patients (238 hips) underwent total hip arthroplasty using the St Michael’s stem and a non-porous screw ring cup. Patients were followed prospectively clinically using the St Michael’s hip score and radiographically. At an average of 11.9 years (10-13.5 years), 55 patients (59 hips) had died, 23 patients (23 hips) were lost to follow-up. The St Michael’s hip score improved from 13.4 pre-operatively to 21.7 (out of a possible 25) at the latest follow-up. Thirty-seven (24%) of the acetabular components have been revised for aseptic loosening and an additional seven components are radiographically loose. No femoral components have been revised. Using Engh’s criteria one femoral component is definitely loose and two femoral components have stable fibrous ingrowth. Significant stress shielding was noticed in 23 hips (17%) without clinical consequences. Minor osteolysis was seen in 13 hips most commonly around the proximal femur and has not caused symptoms. The St Michael’s stem with its large pore size madreporic surface has comparable results to other porous coated stems with smaller pore size.
The St Michael’s stem provided reliable ingrowth and fixation with an acceptable degree of stress shielding. The non-porous screw ring cup had a high failure rate.
Reduction of ultra high molecular weight polyethylene (UHMWPE) surface wear in total knee replacements (TKR) may delay the onset of osteolysis and loosening of components. This study examined the wear of fixed bearing and rotating platform (RP) mobile bearing TKR with two different bearing materials.
Testing was completed on a Leeds ProSim six-station knee simulator under ‘high’ kinematics [
The 1020 GVF fixed bearings exhibited a wear rate of 16.4 ± 4 mm3 per million cycles (MC). This was significantly greater (p < 0.05) than wear of the same bearing material in the rotating platform mobile bearing TKR (10.85 ± 2.39 mm3/MC). Similarly, when uncross-linked 1020 UHMWPE was introduced as the bearing material, a significant (p < 0.05) reduction in wear was observed between the fixed bearing (16 ± 7 mm3/MC) and the RP knee designs (5.85 ± 2.05 mm3/MC).
The RP design decouples the motions between the femoral-insert and tray-insert articulating surfaces. This translates complex knee motions into more unidirectional motions at two interfaces, thus reducing wear under high kinematics compared with fixed bearing TKR. This significant reduction in wear was observed with uncross-linked and moderately cross-linked bearing materials. Design of TKR is an important factor that influences UHMWPE surface wear and may affect long-term success of knee replacements in highly active patients.
Following total hip replacement surgery, fluroscopy studies have shown that a mean separation of 2 mm can occur between CoCr femoral heads and UHMWPE acetabular cups during the swing phase of gait [
A physiological hip simulator was used, loads and motions were applied to approximate in vivo conditions. The alumina ceramic heads and polyethylene cups were 28 mm in diameter and were tested for 5 million cycles in 25% new born calf serum at 1 Hertz. Microseparation was achieved by displacing the femoral head inferiorly during swing phase, where the head contacted the inferior cup rim and was laterally displaced. On heel strike the head contacted the superior cup rim prior to relocation.
The volumetric wear of the polyethylene inserts was approximately four times less under microseparation conditions (5.6 ± 5.3 mm3 per million cycles), in comparison to standard conditions (25.6 ± 5.3 mm3 per million cycles). Deformation of the cup rim was observed, but some of this was attributed to creep. It is postulated that this reduction in wear was due to the separation of the components in swing phase improving the entrapment of lubricant, hence reducing wear via a squeeze film lubrication mechanism. In conclusion, surgical procedures that produce a small and controlled amount of joint laxity and microseparation may lead to a reduction in wear of the polyethylene acetabular cups.
Only recently has the mobility of the ankle joint been elucidated. Sliding/rolling of the articular surfaces and slackening/tightening of the ligaments have been explained in terms of a mechanism guided by the isometric rotation of fibres within the calcaneofibular and tibiocalcaneal ligaments. The purpose of this investigation was to design a novel ankle prosthesis able to reproduce this physiological mobility.
A four-bar linkage computer-based model was used to calculate the shapes of talar components compatible with concave, flat and convex tibial components and appropriate fully congruous meniscal bearings. Three-component designs were analysed, and full congruence of the articular surfaces, appropriate entrapment of the meniscal bearing and isometry of the two ligaments were required.
A convex tibial component with 5 cm arc radius gave a 2 mm entrapment together with a 9.8 mm amount of tibial bone cut, while maintaining ligament elongation within 0.03 % of the original length. The physiological patterns of joint motion and ligament tensioning were replicated. The talar component slid backwards while rolling forwards during dorsiflexion. These movements were accommodated by the forward displacement of the meniscal bearing on the tibial surface under the control of the ligaments. The complementary surfaces provide complete congruence over the entire range of flexion, such that a large contact area is achieved in all positions.
To restore the physiological mobility at the ankle joint, not only should the components be designed to be compatible with original ligament pattern of tensioning, but also these should be mounted in the appropriate position. A suitable surgical technique was devised and relevant instrumentation was manufactured. Five below-knee amputated specimens replaced with corresponding prototype components showed good agreement with the model predictions.
Current three-component designs using a flat tibial component and physiological talar shapes cannot be compatible with physiological ligament function.
Bone-cement shrinkage has never been quantified in a stem/cement/femur construct. We observed gaps around femoral stems in transverse sections of stem/cement/femur constructs; a greater proportion of stem/cement (s/c) interface gaps were found around grit blasted sections of stems than satin finished sections. If s/c gap formation were a shrinkage artifact then mantles with few s/c interface gaps must manifest shrinkage elsewhere, at the c/b interface or voids. ‘Mould-gaps’ at a c/b interface have been described previously but not quantified. We analysed the area of gaps at both interfaces. We hypothesised 1) Total gap area was the same for all transverse sections. 2) Satin sections had greater c/b gap areas than grit sections.
Transverse sections of stem/cement/femur constructs were processed to highlight gap areas. Five stems had a satin finish (Ra 0.75 um) and five were proximally grit-blasted (Ra 5.3 um). Sections were coated with matt black spray paint and then polished with emery paper. This process left all interface gaps and voids filled with black paint, which facilitated digital imaging. Gaps were visually identified and measured using Image-Pro. Gap areas for each transverse section were normalised by the area of cement in that section.
Gaps were not evenly distributed; there was obvious localisation at both interfaces. No significant difference found between surface finishes in total gap area ((satin 3.1% ± 1.4):(grit 3.4% ± 1.5)), supporting our first hypothesis. S/c gap areas were significantly greater around grit blasted sections ((satin 0.1% ± 0.4):(grit 1.9% ± 1.7) p< 0.0001). C/b gap areas were significantly greater around satin finished sections ((satin 2.3% ± 1.3):(grit 1.0% ± 0.9) p< 0.0001), supporting our second hypothesis.
Shrinkage can localise into large interface gaps; which must lead to stress concentrations. C/b gaps are potentially benign as they can fill with bone. Cement failure at points of s/c contact would generate debris hindering bone formation.
There are multiple proximal prosthetic geometries available for a surgeon to select when humeral head replacement is indicated for four-part proximal humerus fractures. We compared different proximal prosthetic geometries in stable and unstable fracture patterns, with a standard tuberosity fixation method.
Simulated four-part fractures were created with an oscillating saw in six synthetic shoulder models. Three different proximal prosthetic geometries used polymetylmethacrelate (PMMA) – a smooth circular shape (SCS), a diamond shape (DS) and an irregular multiple fin shape (IMFS) prostheses. A standardised fixation method using vertical, and horizontal straps along with a medial based cerclage strap was performed. Passive motion was then carried out using a robotic articulator. Interfragmentary displacement was measured from tuberosity to tuberosity as well as tuberosity to shaft using mercury strain gauges.
The least amount of interfragmentary motion occurred when an IMFS was used in a stable fracture pattern. This geometry provided more interfragmentary stability even with the unstable fracture pattern than the DS or SCS. The least stable construct was the SCS prosthesis with an unstable fracture pattern.
Prosthetic geometry does affect stability of tuberosity reconstruction in proximal humerus fractures. An irregular shaped prosthesis augments the fixation construct. When using a smooth prosthetic design a stable fracture pattern must be achieved to prevent excessive interfragmentary motion. A smooth prosthetic design for tuberosity reconstruction is not recommended.
There is little information available regarding mechanical aspects of cemented implant loosening and the initiation and development of cement damage. Previous studies have come to a variety of conclusions about the development of cement damage and the relative importance of voids, the stem/cement interface and the cement/bone interface.
Cement micro-cracks and stem/bone micro-motions were quantified for Charnley Cobra stems under “stair-climbing” loads. Six stem/cement/femur constructs were subjected to loads based on estimated body weight for 300 kcycles at 2 Hz; two additional constructs were not loaded. Transverse sections were cut at 10 mm intervals, stained with a fluorescent dye penetrant and examined using epifluorescence stereo-microscopy.
Despite the aggressive loading, all stem/bone micro-motions were small and all stems were “well fixed” at the end of the loading. The only consistent micro-motion was internal rotation but this did not significantly correlate with cement damage (p=0.9). For cyclically loaded constructs mean crack length was 0.49 mm (SD 0.37, range 0.07 to 4.42) and for non-loaded controls mean crack length was 0.25 mm (SD 0.18, range 0.03 to 1.16). Total crack length (46–281 mm) was significantly correlated (R2=0.819, p=0.002) with femoral head load (0 & 1.0–1.8 kN). There was a significantly (p< 0.05) greater proportion of damage at the cement/bone interface (66% ± 9) than at the stem/cement interface (28% ± 8). A small fraction of micro-cracks involved voids (5% ± 5), but these were significantly (p< 0.001) less than the cement/ bone fraction. Micro-cracks in unloaded specimens were evenly distributed axially (R2=0.0002, p=0.95) consistent with the theory that they were induced by cement shrinkage. ANCOVA for total crack density using head load and axial position as covariates showed a significant positive effect for head load (p< 0.0001) and a significant interaction between head load and axial position (p=0.001); under load, micro-crack density increased proximally, and this effect was stronger with increasing head load.
A high proportion of complications following TKR occur at the patellofemoral articulation secondary to delami-nation and adhesive/abrasive wear. Electron beam cross-linking and melting has been shown to substantially reduce delamination and adhesive/abrasive wear in polyethylene tibial inserts. A series of in-vitro patella wear and fatigue tests were developed to explore the benefits of this material at the patellofemoral articulation.
Patellae (NKII, Sulzer Orthopedics, Inc., Austin, TX) were tested on an AMTI (Watertown, MA) knee simulator articulating against the trochlear grove of the femoral component. The simulator controlled flexion/ extension and patellofemoral contact force. Each test included patellae manufactured from conventional and electron beam crosslinked and melted polyethylene. Three different simulations were created: i) normal gait (5 million cycles) with optimal component alignment, ii) stair climbing (2 million cycles) with optimal component alignment, iii) stair climbing (2 million cycles) with 4° of femoral component internal rotation to simulate a component malalignment condition. In the last two simulations all patellae were artificially aged for 35 days in 80°C air to simulate one aspect of the long term oxidative state of each material.
In normal gait, the unaged conventional and highly cross-linked materials demonstrated similar behaviour. In stair climbing with optimal component alignment, the aged conventional patellae developed cracks by 2 million cycles. In stair climbing with component malalign-ment the aged conventional patellae developed cracks and delamination by 1 million cycles. None of the highly cross-linked components showed cracks or delamination. These results demonstrate the potential advantage of highly cross-linked polyethylene for the patella.
With the growing number of patients that are being treated with hip arthroplasty, the number of patients that require revision surgery is increasing as well. In clinical practice, the diagnosis of a loose hip prosthesis is, in addition of clinical evaluation and radiographic techniques, often made using scintigraphic techniques. However, with regard to the performance of these techniques, reported results have shown to be inconsistent or sometimes even contradict when assessing the acetabular component. Therefore, in order to evaluate the test performance and efficacy of radiographic and scintigraphic techniques in the evaluation of patients suspected of aseptic loosening of acetabular components, we conducted a systematic review and meta-analysis of clinical studies.
In order to identify all studies that examined the use of radiographic or scintigraphic techniques in the evaluation of aseptic loosening of the acetabular component, we used systematic methods to identify English-language published papers and human-adult studies published between January 1975 and December 2001. Using a modified checklist, designed by the Cochrane Methods Group on Systematic Review of Screening and Diagnostic Tests, a quality analysis was performed by two independent reviewers.
There were 18 studies (n=1026) analysing the performance of plain radiography, 24 studies (n=825) regarding contrast arthrography, five studies (n=203) describing the performance of nuclear arthrography and 15 studies (n=549) regarding bone scintigraphy. Pooled sensitivity for plain radiography was 77% (spec. 82%), contrast arthrography revealed a sensitivity of 82% ( spec. 73%), nuclear arthrography 82% (spec.58%) and bone scintig-raphy 70% (spec.73%).
Pooled sensitivity and specificity showed that plain radiography, due to the high specificity, appears to be the technique of first choice in the assessment of patients suspected of aseptic loosening of a acetabular component, followed by contrast arthrography, due its higher specificity compared with nuclear arthrography. However, the methodological quality of the majority available studies was limited.
Correct alignment is important for success in total knee replacement. Currently this is achieved by a combination of intramedullary and extramedullary alignment using jigs and cutting blocks. This multicentre study evaluates the use of computer assisted planning and the interactive guidance of instruments for total knee replacement.
Prior to surgery computer scans of the hip, knee and ankle were performed of patients enrolled in the study. Pre operative planning of the position and size of the knee components was performed by the surgeon using a CT based Vector Vision Navigation System (Brain LAB AG, Heimstetten, Germany). P.F.C.x (De Puy Leeds UK) knee replacements were then implanted in 38 patients. Surgery was carried out according to the standard surgical technique using traditional instruments. Information of the planned and intraoperatively recorded position of the cutting blocks were analysed to check varus/valgus alignment, flexion/extension alignment, the amount of planned resection from both the femoral and tibial bones and the size of the components. Information from all the separate centres was sent to a central data processing base for analysis.
Results were calculated comparing the differences between the planned and performed cuts for each of the different variables studied. Graphs demonstrate the differences in the alignment between that planned by the surgical navigation system and what was actually carried out by the instrumented cuts.
Based on the data obtained from the multicentre study we have concluded that the planned position of the implants using the standard instruments was similar to that using the Vector Vision Navigation System. We believe that it is safe to proceed with surgical navigation total knee arthroplasty using the P.F.C.x total knee prosthesis with Image Guided Surgery and a further multicentre study is currently underway evaluating this.
There are many previous reports dealing with the relationship between the abductor moment arm or femoral offset (FO), and other factors such as the abductor muscle strength after total hip arthroplasty (THA). Moreover, there have been no studies involving quantitative examination of the influence of posterolateral reconstruction on abductor muscle strength and FO. This study was to evaluate posterolateral reconstruction including posterior capsule, piriformis tendon and external rotators in THA and the relationship among the posterolateral reconstruction, abductor muscle strength, and FO.
We arbitrarily selected 48 limbs of 24 patients who underwent unilateral THA using a posterolateral approach. In 16 patients (12 women and 4 men; mean age, 66.8 years; range 50 to 82 years), posterolateral reconstruction was not performed (non- reconstruction group). In eight patients (6 women and 2 men; mean age, 61.6 years; range 52 to 72 years), posterolateral reconstruction was performed (reconstruction group). None of the selected cases were revision cases, cases in which the patient showed marked acetabular dysplasia, or cases involving the osteotomy of the greater trochanter. We compared these two groups. FO was measured on standard antero-posterior hip radiographs. Isometric abductor muscle (N) was measured with hand-held dynamometer. Each muscle strength was converted into a ratio of force to body weight (N/kg), and this ratio was used for comparison.
The reconstruction group showed higher value than the non-reconstruction group on the abductor muscle strength (p< 0.05). The correlation was recognised in the reconstruction group between abductor muscle strength and FO (p< 0.01 r=0.68).
There have been no studies involving quantitative examination of the influence of posterolateral reconstruction on abductor muscle strength and FO. Our results suggested that posterolateral reconstruction and appropriate reconstruction of FO were important in order to obtain the improvement on the abductor muscle strength after THA.
According to the knee simulator test results in 1970s, the total decrease in thickness of UHMWPE tibial tray in combination with ceramic femoral component [F-Comp] was less than one tenth as that of the combination with metal [
The retrieved TKP was implanted in 1979, and retrieved on January 9th in 2002. This TKP consisted of an alumina ceramic F-Comp and a UHMWPE tray combined with a alumina ceramic tibial component. Observations of the surface of alumina F-Comp and UHMWPE tray were carried out using SEM. Shape of UHMWPE tray was determined three-dimensionally. Comparing the result with original shape based on the product’s plan, liner wear and volumetric wear were calculated. Oxidation index was determined by Fourier transform infrared spectrophotometry.
Alumina F-Comp did not have any scratch on the surface by seeing with naked eye. UHMWPE tray had deformation and scratches obviously. The liner wear rate was 37 micrometer/year and volumetric wear rate was 18.8 mm3/year. The oxidation indexes were 0.6 in the unworn area, 1.2 in the worn area and 0.2 in the inner area.
SEM observations of the F-Comp demonstrated no scratch or pit. In contrast, many scratches were clearly observed on the UHMWPE tray. However, higher magnification observations did not demonstrate severe wear, which was shown on the wear analysis of a metallic F-Comp. Oxidation degradation is a problem to solve. However, the low wear rate and mild wear pattern demonstrate that ceramic F-Comp reduced UHMWPE wear.
In clinical studies of cemented total hip arthroplasty (THA), polished stems produce less slippage at the bone-cement interface than roughened stems. Our objective is to assess the effect of stem-cement debonding on the bone-cement interface shear behaviour of hip implants using simplified axisymmetric stem-cement-aluminum models.
We emulated the femoral stems using stainless steel tapered plugs with either a rough (i.e. bonded) or smooth (i.e. unbonded) surface finish. Three different taper angles (5°, 7.5°, 10°) were used for the unbonded constructs. Non-tapered and tapered (7.5°) aluminum shells were used to emulate the diaphyseal and metaphyseal segments of the femur. In all cases, the cement-aluminum interface was designed to have the same shear strength as has been reported for bone-cement interfaces (~8 MPa). The test involved applying axial compressive loading at a rate of 0.02 mm/s until failure. Six specimens were tested for each combination of the parameters.
The unbonded stems sustained about twice as much load as the bonded stem, regardless of taper angle, and the metaphyseal model carried 35-50% greater loads than the diaphyseal models before shear failure or slippage. The unbonded constructs reached peak load with excessive displacement due to creep of the cement mantle while the bonded constructs failed in shear at the cement-aluminum interface. This result supports the hypothesis that the wedging forces created in the unbonded construct increase the compression forces across the aluminum-cement interface, thereby increasing its shear resistance. A finite element analysis predicted that the cement could withstand the hoop stress under these loading circumstances and this prediction was confirmed by visual inspection of the cement after each test.
Our results suggest that smooth or unbonded stems should sustain less slippage and shear damage at the bone-cement interface than roughened or bonded stems due to the wedge-induced compressive stress; this increased load capacity will be particularly valuable when the condition of the bone-cement interface is suboptimal.
This comparative clinical and radiographic study evaluates the role of implant design and positioning on maximum postoperative flexion after TKR.
Two groups of cemented posterostabilised mobile prosthesis were studied. In group A (23 cases) bearing mobility was possible in rotation and translation. In group B (36 cases) solely rotation was possible and the radius of the posterior femoral condyle was larger. In both groups the same medial transquadricipital approach was used and the postoperative rehabilitation was identical.
There were no significant difference between the two groups for patient age, sex, weight and etiology. The average preoperative flexion was 120.8° in group A and 120.7° in group B. The average postoperative flexion at one year was 114.8° in group A and 130.4° in group B. Instability was noted twice in group A and none in group B. Radiographically there was no difference in mechanical axis or patellar height. There was a difference in joint line elevation and anteroposterior joint size.
Higher flexion angle may be related to smaller antero-posterior joint size, better posterior osteophytes removal and larger posterior femoral condyle radius. Greater stability correlates with greater jumping distance over the tibial post. This study showed that deep flexion can be achieved in some patients after TKR, with implications on surgical technique and implant design.
After experimental and preclinical evaluation (HAP Paul Award 2001) of a CT-free image guided surgical navigation system for acetabular cup placement, the system was introduced into clinical routine. The computation of the angular orientation of the cup is based on reference coordinates from the anterior pelvic plane concept. A hybrid strategy for pelvic landmark acquisition has been introduced involving percutaneous pointer-based digitisation with the non-invasive bi-planar landmark reconstruction using multiple registered fluoroscopy images.
From January 2001 to May 2002 a total of 118 consecutive patients (mean age 68 years, 82 male, 36 female, 62 left and 56 right hip joints) were operated on with the hybrid CT-free navigation system. During each operation the angular orientation of the inserted implant was recorded.
To determine the placement accuracy of the acetabular components the first 50 consecutive patients underwent a CT scan seven to ten days postoperatively to analyse the cup position related to the anterior pelvic plane. This was done blinded with commercial planning software. There was no significant learning curve observed for the use of the system.
Mean values for postoperative inclination read 43° (SD 3.0, range 37 to 49) and anteversion 19° (SD 3.9, range 10 to 28). The resulting system accuracy, i.e., the difference between intraoperatively calculated cup orientation and postoperatively measured implant position shows a maximum error of 5° for the inclination (mean 1.5°, SD 1.1) and 6° for the anteversion (mean 2.4°, SD 1.3).
An accuracy of better than 5° inclination and 6° ante-version was achieved under clinical conditions, which implies that there is no significant difference in performance from the established CT-based navigation methods. Image guided CT-free cup navigation provides a reliable solution for future THA.
Hip resurfacing is widely recognised as a bone conserving procedure with respect to proximal femoral resection. However, it has been argued that this is not the case for the acetabulum due to the thickness of the acetabular component and the large diameter bearing surfaces. We have investigated whether the Birmingham Hip is a bone conserving procedure with respect to the acetabular bone stock.
Data was obtained from 257 consecutive Midland Medical Technology (MMT) surface replacements and 458 primary hybrid total hip replacements implanted under our care. The surface replacement group comprised 185 males (185 hips) and 72 females (72 hips) with a mean age at surgery of 55 years. The hybrid primary total hip replacement group comprised 207 males (207) and 251 females (251 hips). The mean age at surgery was 65 years old. In the surface replacement group the mean uncemented acetabular size implanted was 54.88 mm (females = 51.9 mm; males = 57.8 mm). In the hybrid primary total hip replacement group the mean uncemented acetabular size of 55.04 mm (females =52.9 mm; males = 57.2 mm).
Statistical analysis was undertaken to compare the uncemented acetabular sizes in the surface replacement group with the uncemented acetabular sizes implanted in the primary hybrid total hip replacement group. We report no significant difference in the size of acetabular component used for the two groups (p = 0.4629; 95% C.I. −0.28 to 0.61). The effect of gender was analysed and the mean size of uncemented acetabular component implanted in males for the surface replacement group was not significantly different (p = 0.06) to the hybrid primary total hip replacement group. However the mean size of uncemented acetabular component in females for the surface replacement group was significantly smaller (p = 0.016) compared to the primary total hip replacement group.
We conclude hip resurfacing is not bone sacrificing on the acetabular bone stock and can be bone conserving for females.
The use of porous ceramics as bone graft substitutes (BGS) has been under consideration for over 30 years [
It is well established that both pore size [
Phase pure porous HA implants were manufactured using a novel technique [
After 4 weeks new bone had penetrated deep within the macro-pore structure and at high magnification osteocyte-like cells were observed occupying micro-pores within the ceramic struts. Furthermore, there was a significant increase in the MAR of bone formed within and surrounding the PHA (5.21 ìm.day-1, 4.42 ìm.day-1) as compared to the normal turnover rate of control bone (2.07 ìm.day-1, 2.09 ìm.day-1) during weeks 1-2 and 2–3, respectively.
The micro-porous network within the scaffold struts clearly influenced the host response. This could be linked to an associated increase in roughness or surface area, or it may reflect the greater level of strut permeability underlining the importance of nutrient transfer and the promotion of angiogenesis in scaffolds for bone repair.
With 3D CT data of proximal femora it is possible to develop a computer programme for optimising femoral component fit and simulation of implantation. The implantation of the femoral stem can be simulated with any femoral component that has cortical press fit.
Five different currently used femoral components were virtually “implanted” in over 200 different femoral bone data. Optimal femoral fit was defined, when the component showed best diaphyseal and metaphyseal congruent contact with all CT data available. Position of neck and head were secondary, since an optimal press fit situation had priority in our set-up. Best fit was considered taken cortical contact and reconstruction of joint geometry into account.
There were numerous failures in all tested standard components, when correct angle of antetorsion, off-set, and leg length were expected. There were considerably better results with the use of CTX standard prosthesis (CTX-S).
The data of this study indicate a high proportion of less optimal fit with femoral standard components tested in this series. Indication for choosing CTX-S femoral components is dependent upon the individual geometry of dysplastic hip joint and the simulation results of standard components using the VIP method.
Highly polished femoral stems with a double taper have had outstanding long-term clinical results. Recently a stem with a third, cross-sectional taper was introduced with the goal of providing additional stability while still utilising the polished taper concept.
The goal of the present study was to determine if there were differences in the mechanical stability and cement damage due to cyclic loading of a triple-tapered (C-stem, J& J-DePuy) and a double-tapered design (TPS, J& J-DePuy). Six pairs of cadaveric femurs were cemented with either C-stem or TPS stems using contemporary techniques. Specimens were cyclically loaded using a stair-climbing apparatus with femoral head and abductor loads for 1 000 to 266 000 loading cycles. Motion between the stem and bone was measured using a 6 dof measurement system. Following testing, specimens were sectioned at four transverse levels and the number and length of cracks in the cement were measured.
All stems were extremely well fixed after loading. The C-stem did not subside during loading except for one outlier that was cemented ‘high’. The TPS stem had a pattern of rapid subsidence over the first 100 cycles (mean 0.032 mm) followed by a more gradual subsidence (0.05 mm at 266 k cycles). ANCOVA showed that the TPS-stems rotated significantly more than the C-stems (p< 0.0001), that the rotation of both stems increased with number of loading cycles (p=0.022) and that the effect of number of loading cycles was greater for the TPS stems (p=0.047). Total crack length was not a function of number of loading cycles, nor was it different for the two stem designs (p=0.33).
The outlier C-stem had micromotion behavior similar to the TPS stem. The reason for this is unclear, but could be due to reduced lateral-proximal cement. Thus it is possible that both the stem cross-sectional and in-plane shape contribute to the stability of the C-stem design.
Proper pre-clinical testing of cemented THA implants may help to prevent bad implants from entering the market. Within the frame of a multinational EU-program, a finite element (FE) simulation was developed, for FE-based pre-clinical testing of cemented THA stems against the damage accumulation failure scenario. The simulation allows monitoring of cement crack formation and implant migration in cemented THA reconstructions. The current study is concerned with the clinical validation of the test. The damage accumulation failure scenario was simulated for four cemented hip stems, with well-known survival rates. The question was: Can the FE simulation rank the stems according to their clinical survival rates?
Four stems were analysed: the Lubinus SPII, the Exeter, the Charnley and the Mueller Curved. The Swedish hip register [
The Mueller C. produced a considerably higher number of cement cracks than the other three stems. Cracks were formed around the entire stem. The cracked zones often extended over the thickness of the mantle. The Charnley performed better, with a lower number of cracks. Proximo-distal damage pathways were formed, although at a much lower rate than around the Mueller C. The Exeter performed better. Full thickness crack zones were produced only in the proximo-medial region. The Lubinus performed best, with the lowest number of cement cracks. No full thickness cracks were formed. Concerning migration, the Exeter migrated more than the other stems. From the collared implants, the Lubinus SPII showed the lowest migration values.
When considering the number of cement cracks produced in the simulation, the ranking of the stems would be, from superior to inferior: Lubinus SPII, Exeter, Charnley, Mueller Curved. This ranking corresponds to a ranking based on clinical survival rates. The stems behaved according to their design concepts, with the highest migration values for the Exeter stem. In conclusion, the FE simulations produced a clinically valid ranking of four cemented THA implants. This corroborates the use of the FE simulation for pre-clinical testing purposes.
The new 3-Dimensional (3D) polyethylene wear measurement software GAWDI (Genetic Algorithm for Wear Detect Instrument) was developed to evaluate in vivo movement of the femoral head into the polyethylene liner. It enabled to detect 3D position of femoral head against polyethylene socket from two radiographs. Inter observer error of this system was 0.09 mm, intra observer error was 0.08 mm. Fifteen patients after THA was taken anterior-posterior (AP) and semi-lateral radiographs in both standing and supine position one year post operation. The difference of the 3D position of the femoral head was not observed between standing and supine position. However 8.1 degrees (mean) and 0.2 to 16.5 degrees (range) pelvic tilt was observed between these positions. 0.8 mm (mean) difference was observed by 2-Dimensional measurement system although no difference was observed by 3D system. Small separation between head and socket was observed in a few patients. However the influence of pelvic tilt was main origin of the difference between 2D and 3D measurement methods.
The indications for unicompartmental knee arthroplasty (UKA) can be contentious. Concerns exist about implanting a UKA in younger individuals. It has been reported that it is contra-indicated in patients under the age of 60. The suggestion is that younger patients may compromise their outcome after surgery by their increased activity levels. However, the number of publications with data on UKA in young patients is minimal and the age/activity related criteria for UKA remains unknown.
The aim of the study was 1) to confirm that younger UKA patients have higher activity levels than older patients, and 2) to test the hypothesis that younger, more active patients have inferior outcome when compared to older less active patients.
Fifty consecutive patients undergoing UKA who were under 60 years (Group Y) and 50 patients over 60 years (Group O) were recruited. Indications were anteromedial arthritis with full thickness lateral compartment cartilage, a functioning ACL and a correctible varus. All patients underwent Oxford UKA using the minimally invasive technique. This device employs an unconstrained fully congruous meniscal bearing. Outcome was evaluated using Knee Society Scores. Activity level was documented using Tegner Activity Score.
Average age of patients for group Y and O was 55 and 68 years respectively. Minimum follw-up was 2 years. pre-op. knee scores were comparable for each group. (y: 38.8, O: 35.8) and patients in both groups siginificantly improved after surgery. A significant difference in Tegner score was found between the two groups after surgery (y:4.1, O:2.6). More than 50% of younger patients regularly participated in high demand activities like skiing, tennis and manual labour. No statistically significant differences in any other post op. knee scores or complication rate were found despite adequate study power.
Younger patients have increased activity levels after UKA when compared to an older age group. There is no evidence that the outcome of UKA in younger more active patients will be inferior to those who are older and more sedentary.
The disadvantages of sawing for precise bone cuts are well known: untrue cuts, heat and metal wear. The main limiting factors of available milling devices are the difficult handling and high costs, especially if the devices are based on a robot. Supported by clinical users and mechanical engineers a milling concept adopted from industrial machining has been realised in order to overcome this limitations. The “All-in-One Milling-Tool” achieves the same precision of a robot by a mechanically guided milling resection far below the necessary investment for a robot. Once fixed at the femur, the device allows all femural and tibial resections. Three methods are provided for the alignment of the resection planes and will be discussed: intramedullary adjustment, 3D CT-based planning and intramedullar performance as well as the performance under navigation control. All versions are based on a handheld resection and guarantee a visual and haptical feedback for the surgeon. The use of navigation has the advantage of the accurate transfer of the 3D plan into the OR, the interactive guided and facilitated alignment und resection steps and the documentation of planned and actual implant position.
We analysed periprosthetic bone mineral density (BMD) by dual-energy X-ray absorptiometry (DEXA) in patients after uncemented total hip arthroplasty (THA) (press-fit CLS Spotorno stem). Only patients with good clinical outcome (Merle d‘ Aubigne score > 12) were included to obtain normative data for regular bone response.
Two separate studies were performed: A prospective longitudinal study over a time period of 7 years (group A) (n = 26 patients: 12 women, 14 men) and an additional cross-sectional study, mean follow-up13 years (10 to 15 years) (group B) (n = 35 patients: 18 women, 17 men). Regions of interest were defined according to Gruen (ROI 1–7) and as netto average ROI (NETAVG) for the periprosthetic femoral bone. After the initial remodelling process, BMD at 1 year was compared to the 7-year (longitidinal) and to the 13-year (cross-sectional) follow-up values of the affected limb to determine long term periprosthetic changes of bone mineral density.
The longitudinal study (group A) showed BMD values of 91.1% and 92.8% after 1 year, 91.2% and 90.2% after 7 years compared to the initial post-operative values for women and men, respectively. ROIs around the proximal stem (ROI 1 and 7) showed the lowest absolute values and decreased most during follow-up (ROI 1: 80.7% and 84.5%, ROI 7: 71.1% and 75.5% after 7 years, for women and men respectively). In the cross-sectional study (group B) BMD was determined 89.1% and 87.8% after 13 years compared to the initial values of group A for women and men. Distribution of BMD in ROIs 1-7 (group B) showed no significant changes compared to the 1 year and 7 year results of group A. The results reflect normative long term changes in the periprosthetic bone after implantation of THA in defined ROIs of a well functioning tapered corundum-blasted titanium stem.
CT-based, customised femoral stem enables optimal reconstruction of hip mechanics and leg length. However, traditional planning and execution of cup insertion may jeopardise these biomechanical parameters. The aim of this study was to examine the agreement of the preoperative planning of cup position and the final position of the cup.
Thirty total hip replacements with an uncemented acetabular cup (Duraloc, DePuy) or a cemented cup (Elite-Plus, DePuy) were included. A customised femoral stem was used in all hips. On the preoperative X-rays the planned position and orientation of the cup had been marked prior to the surgery. The pre- and postoperative X-ray images were then digitised and scaled. The planned and final positions of the cup centre in the frontal plane was then measured relative to a horizontal line defined by the tear-drops and to a vertical line through the centre of the tear-drop on the operated side. In addition the concurrence between the planned and final cup size was examined.
In the horizontal direction the cups were positioned 1.4 (7.6) mm (median, ±2SD) more medial than planned on the preoperative X-rays. In the vertical direction the corresponding figures were 1.2 (6.6) mm (median, ±2SD) and the cups were usually placed more cranially than was planned. The maximum discrepancy between the planned and final position was 10,6 mm in the horizontal direction (medial) and 7.1 mm in the vertical direction (cranial). In 63% of the hips there was agreement between the size of the cup planned preoperatively and the cup that was finally inserted. In 25% of the hips the final cup was larger and in 12% the final cup was smaller.
In most cases the acetabular cups were inserted within a few millimetres of the planned position. The combination of a standard uncemented or cemented cup with a custom femoral stem enables the surgeon to restore hip mechanics and leg length.
The wrist is arguably the most complex joint in the body and is essential for optimal hand function. The joint may be represented as two roughly orthogonal hinge axes, providing flexion-extension and radial-ulnar deviation. The location and orientation of these axes with respect to the underlying anatomy is essential for the design of successful joint prostheses. A population study was performed in order to obtain the parameters of this two-hinge joint.
Data for 108 normal right wrists was gathered using a Fastrak electrogoniometer with sensors fixed to the distal medial radial styloid and the distal third metacarpal head. Data was recorded as a series of three-dimensional coordinates covering the entire locus of movement.
The two-hinge geometry of the joint was represented mathematically with nine parameters describing the configuration of the axes and two angles controlling rotation about these axes. The configuration giving the closest kinematic match to the experimental data was determined using two nested optimisation processes. During the inner optimisation process, the third metacarpal head was brought as close as possible to each of the experimental points in turn by adjusting the two positioning angles. The sum of distances from each experimental point to the point of closest approach gave the “cost” of the current configuration. The outer optimisation process repeated the inner process iteratively, minimising the cost by adjusting the nine configuration parameters.
The double optimisation method was found to offer an innovative solution to the problem of analysing kinematic data from a population study. The mean joint configuration showed the axis of radial-ulnar deviation to be 1.9 mm (sd = 12.5 mm), distal to the flexion-extension axis, with axes almost orthogonal to one another. This data together with the radii of the rotations is invaluable in determining the optimal articulation geometries for wrist joint replacement prostheses.
To determine the precision of conventional versus computer assisted techniques for positioning the acetabular component in total hip arthroplasty (THA).
Malposition of the acetabular component during THA increases the occurrence of impingement, reduces range of motion, and increases the risk of dislocation and long-term wear. To prevent malpositioned hip implants, an increasing number of computer assisted surgery systems have been described, but their accuracy is not well established.
Using a lateral approach, 150 cups were placed by 10 different surgeons in 10 identical plastic pelvis models. Only the immediate operating field was visible. Pre-operative planning was performed with a computerised tomography scan. Fifty cups were placed free hand, 50 others with the standard cup positioner, and the remaining 50 cups using computer-assisted orthopaedic surgery (Medivision). The accuracy of cup abduction and anteversion was assessed with an electromagnetic system (Fastrak™).
Using conventional techniques, free hand placement revealed a mean precision of cup anteversion and abduction of 10° (range 5.5 to 14) and 3.5° (2.5 to 5) respectively. With the cup positioner, these angles measured 8° (5 to 10.5) and 4° (3 to 5.5) respectively, and using the computer assisted method, the mean cup anteversion precision was 1.5° (1 to 2) and mean cup abduction measured 2.5° (2 to 3.5).
Computer assisted cup placement is a very accurate and reproducible technique during THA. It is clearly more precise than either of the two traditional methods of cup positioning, even for well-trained surgeons.
Modular knee bearings typically consist of a femoral component, a tibial base-plate and a polyethylene insert, which is located in the tibial base-plate using some sort of locking mechanism. Although modular knee bearings offer many advantages there is the potential for micro-motion between the tibial insert and the base-plate.
Tests were performed on six large Kinemax Plus knee bearings (snap-fit design) to evaluate the amount of movement between the tibial inserts and the tibial base-plates. The knee bearings were tested up to one million cycles on the Durham Six-Station Knee Wear Simulator which subjected the bearings to similar motion and loading profiles that would be experienced by the natural knee during walking. The movement of the tibial inserts was measured with dial gauges (accuracy of ±0.01 mm) before and after the bearings were tested on the simulator, when unloaded, and throughout the tests whilst the bearings were being dynamically loaded in the simulator. Movement occurred between the tibial insert and the tibial base-plate after initial assembly due to the snap-fit mechanism used to locate the tibial insert within the tibial base-plate. However, this decreased appreciably when the bearings were loaded in the simulator. The amount of movement did not change with time when the bearings were continuously loaded in the simulator. However, after each test the amount of movement of the tibial inserts, when unloaded, was less than before the test. This was thought to be due to creep of the UHMWPE inserts. The movement between the tibial insert and tibial base-plate in-situ is likely to be much less than that observed by a surgeon at the time of assembly due to loading of the knee bearing in the body. However, the amount of movement when the tibial inserts are loaded may still be great enough to produce a second interface where wear of the tibial insert may take place.
To measure micromotion of an orthopaedic implant with respect to its surrounding bone, Roentgen Stereo-photogrammetric Analysis (RSA) was developed. A disadvantage of conventional RSA is that it requires the implant to be marked with tantalum beads. This disadvantage can potentially be resolved with model-based RSA, whereby a 3D model of the implant is used for matching with the actual images and the assessment of position and rotation of the implant. In this study, an improved model-based RSA algorithm is presented and validated in phantom experiments. This algorithm is capable to process projection contours that contain drop-outs. To investigate the influence of the accuracy of the implant models that were used for model-based RSA, we studied both Computer Aided Design (CAD) models as well as models obtained by means of Reversed Engineering (RE) of the actual implant.
The results demonstrate that the RE-models provide more accurate results than the CAD models. If these RE models are derived from the very same implant, it is possible to achieve a maximum standard deviation of the error in the migration calculation of 0.06 mm for translations in x- and y-direction and 0.14 mm for the out of plane z-direction, respectively. For rotations about the y-axis, the standard deviation was about 0.1 degree and for rotations about the x- and z-axis 0.05 degree. For the femur component, it was also possible to reach these accurate results for non-scanned components. The results show that the new algorithm is an improvement with respect to a study we presented earlier [
Studies with clinical RSA-radiographs must prove that these results can also be reached in a clinical setting, making model-based RSA a possible alternative for marker-based RSA.
The aim of the study was to evaluate THA using Robodoc system for osteoarthritis of the hip joint.
The Robodoc system consists of: 1. the Orthodoc computer workstation that simultaneously displays computerised tomography images of patient’s femur and a selected prosthesis, 2.a five-axis robot, 3.the operating room display, 4. the control cabinet.
Follow up were 3months and 1 year on 27cases (Male 5, Female 22). Selected stems: Zimmer anatomic, 13, Versis 14(VSS,7, VSL,7). Mean age 57.9. Among 27 cases of osteoarthritis, one is after osteotomy and two are after osteonecrosis. Pain, ROM, Radiographs and ADL were evaluated using JOA hip score system. Sockets were fixed with cementless conventional technique.
Mean operating time, 2 hours and 40min.; Mean bleeding, 455 ml; Mean Ant. Version, 29.26 degree (22.0–39.7); Level of osteotomy of the femur neck, Mean, 9.19 mm from the trochanter minor. JOA hip score after THA, 82.20. In one case, 5 mm sinking occurred 5 days after the operation. No intraoperative femoral fractures and varus or valgus insertion of stems occurred in 27cases. The thigh pains were nothing. The patients were discharged at 4weeks after the operation with one crutch. The results showed statistically better fit and fill of the femoral component in the Robodoc system.
The Robodoc system is thought to be safe and effective in producing radiographically superior implant fit and positioning without fractures and other complication. Precise fit of the implant may be increase bone-to-implant contact, providing stress transfer from prosthesis to bone and more bone growth into prosthesis.
Kneeling is an important aspect of daily living. Our goal was to describe the in vivo tibiofemoral kinematics during standing and kneeling after total knee arthroplasty (TKA).
Ten posterior substituting (PS) and 10 cruciate retaining (CR) TKA designs were studied in 18 patients. Radiographs were taken when standing, kneeling at 90°, and kneeling at maximal flexion. An image matching technique provided three-dimensional measurements of the femoral component position relative to the AP midpoint of the tibial baseplate.
When standing, the CR tibiofemoral contact position (medial: 7 mm ± 3; lateral: 6 mm ± 3) was more posterior than the PS design (medial: 5 mm ± 2; lateral: 5 mm ± 2). Movement from standing to kneeling at 90° produced different responses. CR knees translated anteriorly (medial: 4 mm ± 4; lateral: 2 mm ± 6), while PS knees translated posteriorly (medial: 0.2 mm ± 3; lateral: 1 mm ± 4). During kneeling, movement from 90° to maximum flexion produced posterior translation of the femur (CR medial: 5 mm ± 4: CR lateral: 5 mm ± 4; PS medial: 6 mm ± 4; PS lateral: 6 mm ± 3). The relationship between the tibiofemoral contact position and flexion angle during kneeling was more variable for CR knees (r2=0.38) than PS knees (r2=0.64), indicating that PS knees provide a more reliable AP position than CR knees.
PS knees dislocate when the arch of the femoral cam slides over the tibial post; CR knees sublux when the femoral contact position translates beyond the edge of the tibial baseplate. The distance to dislocation averaged 13 mm ± 2 for PS knees, and 20 mm±4 for CR knees.
Many patients wish to resume normal activities, including kneeling after TKA. This study provides information for surgeons and patients considering kneeling after TKA.
The effect of pre-operative pain, physical function, mental function and multiple patient factors on patient outcome following TKR was examined.
After informed consent, 105 patients undergoing primary TKR completed preoperative SF-36 and WOMAC questionnaires and a Knee Society Score (KSS) was determined. These scores were repeated at 12 months. Patient data studied included age, gender, BMI and significant comorbid conditions such as diabetes, cardiac disease, and COPD. Statistical analysis included a univariate analysis, followed by a bivariate analysis and multiple regression analysis.
All physical dimensions of the SF-36, WOMAC and KSS showed highly significant improvements after one year. The KSS improved to a mean of 94.8 (p< 0.000001). For patients greater than 65 years of age, postoperative physical function was returned to normative scores for age matched controls. For patients less than 65, physical function did not reach age matched controls even though similar improvements in physical function were seen. Patients with lower physical function scores (PCS) pre-operatively showed greater improvement postoperatively yet did not reach the same absolute level of function as patients who had higher preoperative physical function. The mean PCS for men increased from 35 to 42, while for women it increased from 29 to 42 (p=0.042). Preoperative mental function (MCS) was a strong predictor of postoperative physical function. Patients with low preoperative MCS and one or more comorbid conditions were 10.1 times more likely to have a poor outcome following TKR.
Knowledge of preoperative physical function, mental function, gender, age and comorbid conditions improves prediction of post-operative physical function after TKR. Patients at high risk for little improvement following TKR are those with low preoperative mental function (MCS< 50) in addition to one or more comorbid conditions. These patients can be identified during the pre-operative period.
Aseptic loosening is one of the most frequent cause of total knee arthroplasty (TKA) failure; it is related to a fatigue-type wear which can rapidly break up a tibial polyethylene (PE) inlay. PE debris production is the result of this wear and depend on contact stress between the components. This crucial parameter is more related to conformity than to load tranfer. That is why mobile bearing TKA seems to represent a valid solution to the PE debris production. In fact this implant offers great tibio-femoral conformity without an increased risk of loosening due to increased axial torque. Mobile bearing TKA also eneables the surgeon to self correct tibial component malrotation. On the other hand this implant could lead to new problems such as bearing dislocation or breakage and a possible new wear pattern at the PE-tibial metal tray interface.
We performed 100 consecutive cemented posterior stabilised TKA using randomly in 50 cases a mobile bearing and in 50 cases the same implant with a fixed bearing. The mean follow up was 15 months. The results in mobile bearing group are the following. Hospital for Special Surgery (HSS) score improved from 38 to 91 after the surgery. Preoperative Range of Movement (ROM) was 71 while the post op value was 107. No lucencies > 1 mm were observed. There were no statistically significant differences among the mobile bearing group and the fixed bearing one. Despite our short follow up, this implant offers the same good clinical results if compared to other devices, and allows the surgeons to correct errors in positioning the implant.
In future we have to consider that this possibility will lead to an abnormal load stresses distribution and to a higher risk of late loosening.
Massive bone replacing endoprostheses have become a well-recognised option in reconstruction of massive bone defects following tumor resections of the humerus, femur and proximal tibia. While the design of such bone replacements is somewhat standardised, massive endo-prosthetic replacements of the proximal radius have not been described. Previous work with radial head replacements for arthritis and fracture indications has been performed, but a massive replacement of the proximal radius has not been reported. The design for such a prosthesis has not been described. Herein, we present our initial case with a massive custom proximal radius replacement, and the incorporated design features.
A 43 year old gentleman presented with progressive destruction of the proximal right radius from meta-static renal cell carcinoma despite radiation treatment. His systemic disease was under satisfactory control. He had undergone a nephrectomy (37 months previously), hip replacement for metastatic disease (28 months previously) and internal fixation of a humerus fracture (10 months previously). Prior treatment of his radius included cast immobilisation and radiation treatment of a pathologic fracture 13 months preoperatively. He refractured his partially healed pathologic fracture two weeks prior to presentation. Following staging with CT and MRI scan, a custom proximal radius endoprosthe-sis was designed that replaced 13 cm of the proximal radius. It was designed with 6 degrees of radial bow. The design specifics will be presented during the presentation. Surgical technique will be demonstrated. By one month postoperatively, his elbow range of motion was from 10 degrees to 140 degrees of flexion, with 90 degrees each of supination and pronation. He continued to have excellent use of his arm until he developed brain metastasis 10 months postoperatively.
Massive custom proximal radius endoprostheses of this design may be useful in the reconstruction of meta-static and primary tumors of the forearm. They are compatible with preservation of motion, and may provide additional stability to the elbow in patients whom soft tissue may be compromised due to tissue destruction or tissue loss secondary to neoplasia.
We present the rationale and design of the DynaPort KneeTest. The test aims at measuring knee patients’ functional abilities in an unobtrusive, user-friendly way. Test persons wear several belts around their trunk and legs. The belts contain accelerometers, the signals of which are stored in a recorder, embedded in one of the belts. The knee test consists of a set of 29 tasks related to activities of daily life (“test items”). Accelerometer signals are analysed in terms of 30 “movement features” (accelerations, angles, durations, frequencies, and some dimensionless numbers). In data analysis, the beginning and end of each test item is marked by hand; otherwise, analysis is automatic.
We compared 140 knee patients with 32 healthy controls and found 541 of the 29 x 30 =870 test item movement feature combinations differed significantly between the two groups. From these 541 combinations the DynaPort knee score is calculated by the weighted averages of movement features per item, then weighted averages of items per cluster (locomotion, rising and descending, transfers, lifting and moving objects), and finally the average of the clusters. In an initial study the test-retest reliability of the knee test proved high, and the test turned out to be sufficiently responsive (0.7 patients’ standard deviations improvement after 24 months). However, it remains difficult to interpret the scores in more meaningful terms than merely “better” or “worse”. Extensive reliability studies in the future will further assess the validity of the test and provide more insight into the meaning of the scores.
The DynaPort knee test may thus become an important instrument for evaluating patients’ functional abilities in knee-related clinical practice and research.
The problem of early mechanical stability and late biological osseointegration of the tibial component is still a debated issue in total knee arthroplasty. We are among those authors that stress the necessity of cementing the tibial component to avoid the risk of failure due to the high torque stresses at this interface. In fact while on the femoral edge a good stability can be achieved even in uncemented implants, the stability of traditional tibial components is harder to obtain even in cemented implants.
To solve this problem it has been proposed to use additional devices such as screws, pegs or keels to better fix the tibial plateau. Tantalum monobloc tibial tray is a new answer to this problem. It consists in a cement-less tibial tray made of porous tantalum with monobloc polyethylene. Chemical, physical and biological properties of the raw tantalum are very similar to those of titanium. Porosity of the processed material is 80% (2–3 times compared to plasma spray, beads and fiber mesh coatings) and pores, which diameter is 650 mm, are fully interconnected in the whole bulk of the implant. This trabecular spongy structure, that is not a coating, allows the bone at the interface to deeply grow into the pores, and to achieve optimal stability. In addiction, the fusion of polyethylene into the tantalum mesh completely abolish the back side wear problem. With this technology is yet in use an acetabular component, with which we have a 5 years experience in 150 implants, and now is available a new tibial plateau; the first implant in Europe was performed in our department.
Despite our short series and follow up (6 implants in 2 months) the properties of porous tantalum, already tested in acetabular implants, represent an alternative to the traditional ways of tibial tray fixation.
Tibiofemoral motions are fundamental to the function (strength, stability, ROM) and longevity of total knee replacements (TKR). Although a wide range of TKR kinematics have been reported, few studies have reported kinematics of a single TKR design utilising a variety of tibial articular surfaces. We hypothesised that increased articular constraint, from four different tibial inserts, would result in reduced tibio-femoral translations during dynamic activities.
We tested 22 knees with excellent early clinical outcomes after primary TKR. All knees received the same PCL retaining arthroplasty; with six curved tibial inserts, six flat inserts, six laterally pivoting inserts and four translating/rotating mobile bearing inserts. Fluoroscopic images of knees were acquired during gait, stair, and deep flexion activities. CAD model based shape matching was performed to determine 3D knee kinematics.
There were significant differences in medial condy-lar translations for all activities, none for the lateral condyle. The medial condyle in knees with flat and mobile bearing inserts translated more anterior with flexion than knees with curved or pivoting inserts. Medial condyle translations were greater in mobile bearing knees than knees with flat inserts.
Our results indicate that condylar motions in TKR’s during dynamic activities can be modulated in a reasonably predictable manner by varying the degree of tibio-femoral constraint. Furthermore, the results show that significant control of translation can be achieved through asymmetric tibial insert conformity. These findings suggest it is possible to achieve a particular pattern of tibio-femoral translations and rotations in vivo through careful selection or design of the articular geometry.
Improving the wear resistance of polyethylene is considered paramount to improving knee implant longevity. Consequently, a range of polymer fabrication techniques have evolved in the quest for a highly wear resistant material. The objective of this study was to explore the wear performance of polyethylene as fabricated in a variety of ways.
The following materials were prepared, sterilised, artificially aged, and machined into wear specimens (n = 4 for each material): Compression molded GUR1050 with three levels of cross-linking (120 kGy, 65 kGy, and 0 kGy irradiation – control); ram extruded GUR4150 high modulus material; compression molded GUR4150 low modulus material; and HSS/PolySolidur/Hoechst reference polyethylene. Using a custom designed joint articular wear simulator, samples were loaded for 2 million cycles at a frequency of 0.5 Hz under loads of 2.1 kN. Tests were stopped every 250 000 cycles; and wear surfaces were examined microscopically for surface damage (pitting, cracking, delamination).
After 2 million loading cycles the following specimens were pitted and delaminated: 2 GUR1050 control samples, 3 GUR4150 high modulus specimens, and all 4 reference polyethylene specimens. Burnishing, but no pitting, was seen in all GUR1050 elevated cross-linked polyethylene specimens, and in all GUR4150 low modulus specimens.
The materials tested in this study represent a broad range of fabrication techniques. Differences in starting resin cannot fully account for the differences in wear behaviour seen between the groups; as damage was not limited to one resin group. The cross-linked specimens were melt-annealed, prior to cross-linking. It is possible that this processing step, and not the actual cross-linking, contributed to the improved wear performance of this group. However, of most interest is the comparable wear performance of GUR1050 cross-linked polyethylene and GUR4150 low modulus polyethylene suggesting that cross-linking polyethylene is not the only route towards obtaining a polyethylene with superior wear characteristics.
Range of motion after total knee arthroplasty (TKA) is increasingly an issue of critical concern in the performance of knee replacements and their ability to meet the functional demands of diverse patient populations. The goal of this study was to measure maximum weight bearing flexion in patients with one knee replaced using a posterior cruciate retaining (CR) device and the other a cruciate substituting (PS) device on a prospective basis.
Sixteen patients (32 knees) with bilateral TKA and excellent clinical/functional outcomes at least one year after surgery participated in this study. Eight patients received knee replacements from one surgeon, and eight patients received knee replacements of another design from a second surgeon. Their knees were imaged using fluoroscopy as the patients were asked to bend to maximum flexion with their foot on a 25 cm step. CAD model based shape matching techniques were used to measure knee flexion, axial rotation, and the anterior/ posterior (AP) location of tibio-femoral contact relative to the AP centre of the tibial insert. Paired t-tests were used to evaluate differences in means (p = 0.05).
PS knees had larger average flexion angles (121±8 deg vs. 114±5 deg, p=0.01) and greater femoral rollback (14±3 mm vs. 12±3 mm, p=0.02) than the CR knees. There was no difference in axial rotation (6±4 deg vs. 5±6 deg). The same trends were observed within the single design subgroups.
In patients with heterogeneous bilateral TKA, greater femoral rollback and weight-bearing flexion is exhibited by the knee with a posterior stabilised TKA.
Hip revision failures are partly due to the poor quality of femoral bone stock. Several work showed that bone reconstruction without grafts is possible around a non cemented, stable stem. It is enhanced by a transfemoral approach.
We designed the Restoration TM DLS stem (anatomical, S curved, HA coating and distal locking to ensure a primary stability).
Preoperative planning is necessary. The operative technique is based on a double postero-lateral femoral flaps approach. An innovating and modular instrumentation was developed. It rests on a femoral clamp that solidarises the femur and the trial stem, and allows a precise adjustment of the length and the stem anteversion. A targeting device allows a precise distal locking of the final implant. Osteosynthesis of the flaps is carried out by cerclages in order to bring the bone around the prosthesis.
Forty-seven revisions cases were followed up. No major peroperative incident has occurred. We report one case of locking error. Compared to the planning, the instrumentation was considered to be precise in 94% for the adjustment of the leg length and of the ante-version. The bone adaptation around the implant was generally correct. In 21 cases, it was necessary to carry out metaphysal re-calibration or osteotomies for correction of a femoral deviation. The synthesis of the flaps is stable in 92%. For follow up greater than 3 months, the consolidation of the osteotomies is effective in 90%.
This study made it possible to validate a surgical procedure by transfemoral approach that makes safe implant and cement removal. It also allowed us to validate an innovating, precise yet flexible instrumentation that allows, after preoperative planning, the anatomical reconstruction of the femur around the stem. A perfect proximal adaptation of the femur to the implant is necessary to the good tolerance of the distal locking.
Observations of knee arthroplasty kinematics generally show differences in anteroposterior translation when comparing posterior cruciate retaining (CR) and posterior stabilised (PS) designs. However, the PS cam/post mechanism is not engaged in extension. We hypothe-sised that there would be little difference between CR and PS knee kinematics during stance in gait.
Videofluoroscopy and shape matching techniques were used to quantify motions of 47 fixed-bearing knee arthroplasties (24 CR, 23 PS) during gait and stair-climbing in consenting patients with excellent clinical/ functional performance at least one year post-surgery. The average centre of rotation (COR) was computed for each knee during the two activities; a lateral COR (−50% to 0%) indicates anterior femoral translation with flexion, a medial COR (0% to +50%) indicates posterior femoral translation with flexion.
There was a significant difference between the average COR in the PS (+9%) and CR (−15%) knees for the stair climbing activity (p< 0.001), but not the stance phase of gait (−5% vs. −14%, respectively, p=0.664). The COR was more lateral for the stance phase of gait than for stair climbing in the PS knees (p=0.008), but not the CR knees (p=0.948). All knees showed more axial rotation during the stair activity (8°) than the stance phase of gait (5°, p< 0.001).
During stance in gait, there were small but not significant differences in the centre of rotation between the CR and PS knees. For stair climbing, there were significant differences between CR and PS knee kinematics. These observations are consistent with the hypothesis that CR and PS kinematics ought to be similar near extension, where the articular constraints are similar, but might differ in deeper flexion activities where the intrinsic constraints of the arthroplasty are different. An improved understanding of arthroplasty function should facilitate further evolution of design, surgical techniques, and numerical analyses to optimise patient performance.
Many recent studies emphasise the importance of surgical technique for achieving long-lasting, pain-free, optimally functioning TKR. However, little information exists in the accuracy with which each step of the TKR procedure is performed using current instrumentation. This study examines the accuracy with which each step of the TKR procedure using current, intramedullary instrumentation.
Twenty primary TKR were performed using a current, intramedullary instrumentation system. The accuracy of each femoral and tibial cut and the accuracy of the final frontal and sagittal limb alignment were measured using an image-free computer assisted navigation system. The system made it possible to measure: 1) frontal femoral implant alignment; 2) sagittal femoral implant alignment; 3) femoral implant rotational alignment; 4) frontal tibial implant alignment; 5) sagittal tibial implant alignment; 6) frontal limb alignment; 7) sagittal limb alignment. Alignment results are expressed in terms of the mechanical axis. Optional results are a frontal and sagittal axis of 90° relative to the mechanical axis. The optimal femoral rotational alignment is 3 degrees externally rotated from the posterior femoral condyles or zero degrees externally rotated from Whitesides line.
The alignment results were: 1) frontal femoral alignment: 89° (range 87 to 92°); 2) sagittal femoral alignment: 89 (range 88 to 193°); 3) femoral rotational alignment: 1° external rotation vs. femoral condyle; 2 degrees internally rotated vs. Whitesides line (range 0.5° to 3.5°); 4) frontal tibial alignment: 88° (87° to 93°); 5) sagittal tibial axis: 87° (range 86° to 91°); 6) frontal limb alignment: 179° (range 177 to 181°); 7) sagittal limb alignment 179° (range 174 to 180°).
Intramedullary instrumentation allows reasonably accurate and reproducible frontal limb alignment. There is a tendency to leave the limb in slight flexion when using intramedullary instruments. There is also a consistent tendency to internally rotate the femur with current anterior –posterior alignment guides and to excessively posteriorly flex the tibial component, although almost all of the 20 TKR’s resulted in final limb alignment within 3 degrees of frontal and sagittal axes. Very few (4) TKR’s were performed in which all of the measured steps were within 3 degrees of the optimal position.
The study emphasises that current intramedullary instrumentation does not result in a high incidence of accuracy when each step of the procedure is measured. Computer assisted techniques permit measurement of the steps of the TKR procedure with a high degree (error < 1°) of accuracy. Longevity, pain-relief and funtion should be related to the total accuracy with which TKR are performed.
The aim of the study was to measure in-vivo the 10-year linear and volumetric polyethylene wear of a fully congruent mobile bearing unicompartmental knee arthroplasty (OUKA).
We studied six OUKA’s that had all been implanted 10 years previously. Each patient was examined in even double leg stance at a range of knee flexion angles, in a calibration cage. A stereo pair of X-ray films was acquired for each patient at 0°, 15° and 30° of flexion. The films were analysed using an RSA style calibration and a CAD model silhouette-fitting technique. The position and orientation of each femoral and tibial component was found relative to each other and the bearing position inferred. Penetration of the femoral component into the original volume of the bearing was our estimate of linear wear. The volumetric wear is calculated from the measured linear wear and the known surface area of the bearing. In addition eight control patients were examined less than 3 weeks post-operation where no wear would be expected.and 30We studied seven OUKA’s that had all been implanted at least 10 years previously. A stereo pair of X-ray films was acquired for each patient at 0 Results: The control group showed no measured wear. The seven OUKA’s had an average maximum depth of linear penetration of 0.40 mm at a mean follow-up of 10.9 years. The linear wear rate was 0.033 mm/year. The volumetric material loss was 79.8 mm3. If a steady gradual material loss is assumed, 8 mm3 of UHMWPE was lost per year.
Polyethylene particulate wear debris continues to be implicated in the aetiology of component loosening and implant failure knee following arthroplasty. The OUKA employs a spherical femoral component and a fully congruous meniscal bearing to increase contact area and theoretically reduce the potential for polyethylene wear. The results from this in-vivo study confirm that the device has low 10-year linear and volumetric wear in clinical practice. This may protect the device from component loosening in the long term.
We would like to present an overview of a research programme that aims to improve drastically the state-of-the-art in shoulder joint replacement surgery. Development of Improved endoProstheses for the upper EXtremities (DIPEX), as this effort is called, is a clinically driven multi-disciplinary programme consisting of many contributory projects. Within the project two main directions of research can be distinguished: the development of an improved shoulder prosthesis and the improvement of the surgical process. For this audience, we would like to present our approach to the improvement of the surgical process.
A newly designed visualisation platform called DSCAS (Delft Shoulder Computer Assisted Surgery) will play a central role within the DIPEX project. This platform is not only able to visualise CT and MRI datasets with a range of different algorithms, but is also able to calculate parameters that are essential for surgery and extract information from these datasets. The extracted information serves as input for the Delft Shoulder Model, an inverse dynamic musculo-skeletal finite element model, with which the effect of surgical decisions on the functional outcome, i.e. range of motion, stability of the joint etc. can be predicted and visualised.
Concerning per-operative guidance two approaches are currently studied – a camera-based approach and mechanical approach – that have both their advantages and disadvantages. Comparison of the two approaches in an experimental setting as well as in a clinical setting is part of the DIPEX project.
The ultimate goal of this part of the DIPEX project is to create a surgical support infrastructure that can be used to predict the optimal surgical protocol and can assist with the selection of the most suitable endoprosthesis for a particular patient. Subsequently, this support infrastructure must assist the surgeon during the operation in executing his surgical plan.
Lubricated metal-on-metal (MOM) bearing surfaces are not easily separated, unlike ceramic- or metal-on-UHMWPE (COP, MOP), due to interfacial forces and low diametric clearance that provides a ‘suction-fit’. In vivo videofluoroscopic studies have shown that patients with MOP/COP THRs exhibit separation of bearing surfaces by up to 3.1 mm during normal gait and 5.4 mm during active abduction while patients with MOM bearings do not. In this regard, MOM bearings may have similarities to constrained bearings with the potential to lower dislocation rates.
All patients under 70 years old undergoing primary THRs for primary osteoarthritis were prospectively registered on a computer database. From 1993–8, patients were offered a 28 mm COP bearing. After 1998, as part of a clinical trial, a 28 mm MOM bearing was inserted instead. For all cases, we used a metal-backed, uncemented acetabulum allowing a modular 10-degrees posteriorly augmented insert (Duraloc/PFC/Ultima, J& J) and the same cemented femoral stem (Ultima, J& J). The same experienced surgeon performed all operations using the posterior approach. Interfacial forces between bearing surfaces were assessed in vitro with a variable-speed-motor winch (APT) and a load-cell (E375/RDP) by recording peak-retaining-forces of bearing couples during separation with variable impact-distraction velocities. Statistical analysis used the Chi-square and student’s t-test.
We identified 140 COP THRs in 129 patients and 109 MOM THRs in 100 patients. Nine of 140 (6.4%) COP bearings dislocated within 3 months of surgery compared to 1 of 109 (0.9%) in the MOM group (p=0.024). No significant differences were identified between groups when comparing patient and prosthesis factors. In vitro assessment demonstrated that MOM bearing possessed interfacial retaining forces up to 30N more than COP bearing (p< 0.001).
This study demonstrates a significantly lower dislocation rate in THR with MOM bearing compared with COP. A potential explanation is the differential ease of separation that the two lubricated bearing couples possess due to interfacial retaining forces (viscous tension and ionic adhesive forces) exerted by the lubricating fluid.
Many total knee replacements (TKR) are designed with more conforming articular geometry to increase the femoral contact area and decrease surface stresses. These designs are supported by studies suggesting that implants with coronally flat articular surfaces are vulnerable to medial-lateral lift-off and edge-loading on the polyethylene insert. However, few retrieved inserts from contemporary TKR’s have shown wear consistent with this loading mechanism. This study presents wear measurements from 37 consecutively retrieved polyethylene inserts of the same PCL-retaining design with coronally flat-on-flat articulations. If substantial edge-loading occurred in-vivo, it was hypothesise that wear would be located closer to the medial or lateral edge of the articular surface with a high incidence of delamination.
Inserts were retrieved at autopsy (n=12) after 41 (15–74) months in-situ and at revision TKR (n=25) after 26 (1–71) months in-situ. Reason for revision was infection (28%), patellar component complications (24%), loosening (24%), patellar resurfacing (20%), and supra-condylar fracture (4%). Articular damage was measured using light microscopy and digitising the circumference of each damage region on calibrated images. Surface deformation was measured relative to unused control inserts using a hand-held digitising stylus.
Wear patterns were not significantly different between autopsy or revision retrievals (ANOVA, p> 0.05). Articular wear covered 48%+16% and 47%+14% of the medial and lateral surfaces, respectively. The most frequent wear modes were burnishing and scratching. Delamination occurred on 4(11%) inserts, but involved < 2% of the articular surface. Wear patterns were internally rotated and centrally located. Not one insert had a wear area centroid located in the medial or lateral third of the articular surface. Surface deformations were greatest in the inserts’ central region and the linear deformation rate decreased with time.
Concerns of high contact stresses associated with edge-loading were unsupported by these retrievals. Condylar lift-off, if it occurs, does not appear to substantially impact polyethylene damage in coronally flat-on-flat articulations.
In vitro loading of the proximal femur has improved our understanding of stress shielding after total hip arthroplasty. However, previous load simulators often use simplified loading regimens that may not produce physiologic baseline strains. The purpose of this study was to compare the femoral strain levels produced when using simplified and more complex loading.
A mechanical load simulator was developed which could simultaneously apply a spinal load and nine of eleven available muscle loads to the proximal femur in heelstrike and stair climbing modes. Computer controlled electromechanical actuators were attached to a strain gauged fresh cadaver femur (donor body weight 39 6kg) with metal cables. A spinal load of 668 N (SPL) was applied alone and in combination with individual muscle loads of 267 N to determine the effect of each muscle on femoral strain. The magnitude and direction of the joint reaction force (JRF) was monitored in real time by a three-dimensional force transducer proximal to a metal acetabulum. Anterior, middle and posterior portions of the gluteus medius (ABD), iliotibial band (ITB), short external rotators (SER), vastus lateralis, adductors, rectus femoris, hamstrings, iliopsoas, and gluteus maximus were simulated.
SPL was applied and ABD and ITB were adjusted to produce a JRF magnitude of 2.0 BW. SPL was applied with two combinations of nine muscle loads adjusted in heelstrike mode to produce a JRF magnitude of 2.0 and 2.5 BW and JRF trajectory aligned within one degree of the radiographically determined compression trabecular stream axis.
Both nine-muscle combinations produced lower medial compression strains and substantially lower lateral tension strains than SPL+ABD+ITB in heelstrike and stair climbing. Simplified loading caused a bending moment in the proximal femur resulting in higher strains. Combined loading at 2.5 BW produced compression at 10 of 12 gauges in heelstrike mode and 9 of 12 gauges in stairclimbing.
Total knee replacement (TKR) is intended to satisfy patients rather than surgeons. The latter could be more optimistic when they assess the outcome of their own operations. We envisage that there is a variation between patients’ own assessment and those of surgeons. This study reviewed long-term results of TKR and compared between patients’ assessment and surgeon’s assessment.
Four hundred and six TKR were performed between 1980 and 1994 in a DGH by one surgeon using single knee prosthesis. The follow up was up to 14 years (mean 7.2). Clinical assessment was done by the surgeon in out patient clinic and was compared to the patients’ assessment, which was done through a confidential postal questionnaire (PQ).
Response rate to PQ was 84 %. There was an obvious discrepancy in reporting pain and patients’ satisfaction between the two methods of assessment however there was similarity in other parameters. Surgeon rated satisfaction more highly and patients reported more pain in PQ. In this study revision rate was 4 %, infection 1.7 %, instability 1.4 % and patellar pain 20 %.
There is a variation between patients’ own assessment and those of surgeons. For accurate assessment of the outcome of TKR we recommend the use of postal questionnaire alongside clinical assessment.
Surgical navigation, coupled with preoperative plans, allows surgeons to plan and execute procedures to improve the likelihood of positive outcomes. In real life these navigation systems, which track both the patient and the surgical tools, are not absolutely accurate. Therefore, there is a need to know how much error there may be in the navigation system, so that the surgeon can assess the effects of possible errors in positioning.
The methodology for assessing the accuracy of a surgical navigation system is similar across surgical specialties. We developed a framework for assessing the accuracy of the HipNav system, a computer assisted surgical system used for planning and intra-operative surgical navigation for total hip arthroplasty. This framework can be adapted to other systems and surgical procedures. To assess navigational accuracy, we compared acquired values to a ground-truth model: rigid plastic Sawbones pelvii with mounted fiducials and acetabular implants, whose positions were measured with a coordinate measuring machine. We then identified the individual components of the system that can contribute to overall accuracy, and characterised their contributions to the accuracy of the system. We also measured the end-to-end accuracy of the HipNav system, from initial CT scan through to acetabular cup orientation. This value is of direct importance to the practicing surgeon, and indicates how far off the final measured orientation of the cup may be from its actual location. For the HipNav system, we found that the end-to-end square root of the mean square error was 0.82° in abduction and 0.76° in version.
The accuracy of a surgical navigation system is of vital importance to insure that a preoperative plan is executed properly. To measure the accuracy of a navigation system, accurate models that reflect the relevant anatomy are necessary, and allow true measurement of end-to-end and component accuracy. This example shows how the accuracy of HipNav was assessed, and that the final orientation of the acetabular implant was accurately guided.
Osteolysis secondary to polyethylene wear is the most serious aseptic long-term complication following THR. Studies have shown that fixation with screws, modularity and lack of extensive bone ingrowth are associated with increased osteolysis. This study examines the initial experience with a cup designed to address these issues.
One hundred and twenty-seven consecutive primary THR were performed between 1997–1999 using unce-mented monoblock, elliptical, tantalum cup without screw holes. Average follow-up 40 months (range 24 to 61). 79 THR in females, 48 in males. 48% THR hybrid fixed, 52% uncemented. Average age 61.6 years (range 19 to 88). Pre and post-operative clinical assessment with Harris hip score (hhs), WOMAC, SF-36. One independent, blinded observer performed zonal radiographic analysis with modified DeLee and Charnley method.
Average hhs at recent follow-up 93 (range 85 to 100). All shells appear fixed with bone ingrowth. Dome-gaps present in 6 cups post-op; all have filled in. Radiolucencies at follow-up: 4% zone 1, 8% zone 2; none greater than 1 mm. No cup migration. 8 cup related complications: 5 dislocations (4%) 1 subluxation, 2 undisplaced rim fractures (1.7% – no treatment). 3 dislocations, 1 subluxation occurred more than three months post-op. 3 revisions: 1 deep wound infection, 1 liner exchange (using reaming technique), 1 femoral head exchange.
Uncemented monoblock, elliptical tantalum cup without holes provides secure, symptom-free fixation at 4 years. No complications associated with use of tantalum. Elliptical shape associated with dome gaps, all of which appeared to fill by 3 months. Monoblock design results in increased polyethylene lip prominence associated with 6 cases of instability. Effect of prominent rim on impingement and long-term wear requires careful follow-up.
Pelvic osteolysis secondary to polyethylene wear is a major complication following THR. Identification of implant specific characteristics associated with osteolysis is essential. The purpose of this study is to compare incidence of CT scan identifiable osteolysis in 2 groups of young, active patients following THR; one with multi-holed acetabular shells with screws, one with cups without screw holes.
Between 1990–1993, 77 patients (85 hips) underwent THR with a cementless titanium, multi-holed shell with screws, modular, compression molded polyethylene and an uncemented titanium femoral stem. Average follow-up: 9 years, average age at surgery: 51 years. Between 1984–1987, 163 patients (183 hips) underwent THR with a cementless cobalt-chrome, solid shell, modular, heat-pressed polyeth-ylene liner and uncemented cobalt-chrome femoral stem. Average follow-up: 16 years, average age at operation: 52 years. All polyethylene was irradiated in air. At most recent follow-up, CT scans with metal suppression software was obtained to evaluate incidence of pelvic osteolysis. Patients classified: Group 1-no osteolysis, Group 2-cavitary osteolysis, Group 3-segmental osteolysis.
Patients with titanium, multi-holed shells had: Group 1-50.0%, Group 2-38.7%, and Group 3-11.3%. Patients with cobalt-chrome, solid shells had: Group 1-59.3%, Group 2-33.3% and Group 3-7.4%.
Although the patients with solid cups had much longer follow-up, less secure capture mechanism, less congruency between polyethylene and shell, and heat-pressed polyethylene, the incidence and extent of pelvic osteolysis was less than in the patients with multi-holed shell with screws. The presence of 6.5 mm cancellous screws is a serious independent risk factor for pelvic osteolysis following THR.
In PCL-retaining TKA, tension in the PCL is sensitive to changes in the posterior slope of the tibia component. However, it is not understood how PCL tension, in combination with the absence of the ACL, affects knee kinematics. This study demonstrates the effects of varying posterior tibial slope on the tibiofemoral and patello-femoral kinematics after PCL-retaining TKA.
Eight fresh-frozen lower limb specimens were mounted in a kinematic knee simulator. External forces were applied to create a deep knee bend from 0–110 degrees of flexion, while the three-dimensional motions of the femur, patella and tibia were tracked in real time using a motion analysis system. A PCL-retaining TKA was implanted into each cadaver with the tibial component matching the natural posterior slope of the tibia. After testing, the tibial slope was reduced by four degrees compared to the natural slope, then increased by four degrees compared to the natural slope. With each change in slope, the kinematics of the knee were recorded.
A dramatic change in femoral rollback was observed with increasing slope of the tibial component. In full extension, matching the natural tibial slope displaced the femur 5.7 ± 1.5 mm posteriorly, while more anterior slope and more posterior slope displaced the femur 5.1 ± 2.6 mm and 8.7 ± 2.0 mm posteriorly, respectively. Paradoxically, increased posterior slope resulted in less rollback of the femur during flexion. At 100° a of flexion, total rollback was 11.8 ± 2.6 mm in the intact knee, 6.9 ± 2.4 mm with the natural slope, 9.0 ± 2.8 mm with the anterior slope, and 5.7 ± 2.3 mm with the posterior slope.
Preserving the PCL allows the femur to rollback on the tibial plateau with knee flexion. However, increasing the natural slope of the tibia causes a significant posterior shift of the femur in extension thus reducing rollback in flexion.
Proximal femoral bone loss is often observed after total hip arthroplasty (THA) and continues to complicate revisions. The purpose of this study was to evaluate the clinical and radiographic outcomes of patients with the unusual finding of proximal femoral cortical hypertrophy after THA or endoprosthesis.
Three patients were identified with femoral stem tip perforation through the posterolateral femoral shaft cortex. Known risk factors for perforation were osteoporosis, distal osteolysis causing late stem migration, and endoprosthesis after previous fracture/internal fixation. Two patients had dual energy x-ray absorptiometry (DXA) of both hips. Follow-up was 16, 17 and 28 years.
All three patients had clinically stable femoral components and none had thigh loading pain. All three patients had dense cortical bone buttressing the undersuface of the implant collar and a dense medial femoral cortex. Proximal femoral DXA regions of interest were 120 and 145% of the contralateral femur in the migration and post-fracture endoprosthesis patients, respectively.
The endoprosthesis patient was revised to a THA 28 years post-operatively due to acetabular erosion. Excess dense cortical bone in the proximal femur was removed with a high speed bur and enabled revision with a primary non-cemented femoral component.
Common factors which appeared to be necessary for a stable implant with proximal femoral densification included collared femoral components, stem alignment more vertical than the femoral neck axis, stem perforating the posterolateral femoral cortex, no inhibition of translation along the stem axis by cement or biological ingrowth, and not having the implant revised despite its unorthodox appearance.
Long-term maintenance of the proximal femoral cortex after THA or endoprosthesis is possible. Paradoxically, a rare subset of the complication of femoral shaft perforation demonstrated by these anomalous cases suggested an alternative approach to the prevention of stress shielding bone loss after THA.
Radiolucencies are generally thought to be a manifestation of loosening. They are commonly seen under the tibial component of the Oxford Unicompartmental knee replacement. However, they are not associated with long term failure [
Eight medial Oxford Unicompartmental knee prostheses were examined post-operatively, at 12 months and at 24 months using Roentgen Stereophotogrammetric Analysis (RSA). The serial radiographs were calibrated and three dimensional CAD models were matched to the extracted component shapes. Implanted bone marker balls were then selected on all radiographs. The components were superimposed. Migration calculation was achieved by comparing relative positions of components to bone marker balls in the serial radiographs. Fluoroscopically screened X-rays were taken to determine whether there were any radiolu-cencies under the tibial component.
By 12 months, the femoral component had migrated significantly anteriorly (0.35 mm) and proximally (0.61 mm). The tibial component had migrated significantly distally (0.42 mm) and anteriorly (0.47 mm). Although on average there appeared to be a small further migration between 12 and 24 months, this was not statistically significant in any direction.
Six of the eight patients had radiolucencies at 24 months. None of the radiolucencies were was complete. The maximum radiolucency was 1 mm thick and the average was 0.57 mm. There was no correlation between radiolucency and migration.
The proximal femoral migration and distal tibial migration can be explained by the load across the knee. We cannot yet explain the anterior tibial migration. Radiolucencies almost always occur and are not related to migration.This confirms they are not associated with loosening.
The disadvantages of sawing for precise bone cuts are well known: untrue cuts, heat and metal wear. The main limiting factors of available milling devices are the difficult handling and high costs, especially if the devices are based on a robot. Supported by clinical users and mechanical engineers a milling concept adopted from machining has been realised in order to overcome this limitations. The „All-in-One Milling-Tool“ achieves the same precision of a robot by a mechanically guided milling resection far below the necessary investment for a robot. Three methods are provided for the alignment of the resection planes and will be discussed: intramedullary adjustment, 3D CT-based planning and intramedullar performance as well as the performance under control by navigation. All versions are based on a handheld resection and guarantee a visual and haptical feedback for the surgeon. The use of navigation has the advantage of the accurate transfer of the 3D plan into the OR, the interactive facilitated alignment und resection steps and the documentation of planned and actual implant position.
When the Oxford unicompartmental meniscal bearing arthroplasty (UCA) is used in the lateral compartment of the knee 10% of the bearings dislocate. An in-vitro cadaveric study was performed to investigate if the anatomy and joint geometry of the lateral compartment was a contributory factor in bearing dislocation. More specifically, the study investigated if the soft tissue tension of the lateral compartment, as determined by the length of the lateral collateral ligament (LCL), was related to bearing dislocation. A change in length of greater than 2 mm is sufficient to allow the bearing to dislocate.
The Vicon Motion Analysis System (Oxford Metrics, Oxford, UK) was used to assess length changes in the LCL of seven cadaveric knees. Measurements were made of the LCL length through knee flexion and of the change in LCL length when a varus force was applied at a fixed flexion angle. Measurements were made in the normal knee and with the knee implanted with the Oxford prosthesis.
In the intact knee the mean LCL change was 5.5mm (8%) over the flexion range. After implantation with the Oxford UCA the mean change in length was only 1 mm (1%). There was a significant difference in the LCL length at 90° (p=0.03) and 135° (p=0.01) of knee flexion compared to the intact knee. When a varus force was applied the LCL length change of the intact knee (5.4 mm) was significantly different (p=0.02) to that of the knee with the prosthesis implanted (2.7 mm)
This study used a new method to dynamically measure LCL length. It found that after implantation of the Oxford lateral UCA the LCL remains isometric over the flexion range and does not slacken in flexion as it in the normal knee. This would suggest that the soft tissue tension was adequate to contain the bearing within the joint.
However, when a varus force was applied the LCL did not sufficiently resist a displacing force producing an LCL length change greater than 2 mm.
The evidence provided by this study is contradictory. The “lack of change in LCL length through flexion” suggests that the ligament remains tight through range and is unlikely to allow dislocation. However, the amount of distraction possible when an adducting moment is applied is sufficient to allow bearing dislocation. The length tension properties of the lateral structures are therefore implicated in the mechanism of dislocation.
To determine the effect of altering tibial slope on the two-year range of motion (ROM) of patients undergoing condylar total knee replacements (TKR).
A single surgeon performed 74 primary cemented posterior stabilised tri-compartmental TKR’s on 56 patients (19 male, 37 female) with mean age of 67.1 years, height 66.7in., weight 187.4 lb, and BMI 29.58 kg/m2. 51 had osteoarthritis, and five had rheumatoid arthritis. A standard surgical technique was employed utilising flexion axis localisation to position the femoral components. Patients were followed for two years minimum using outcome measures and x-rays. Knees where tibial slope was restored to a degree angle equal to, or slightly greater than, their pre-op slope (group 1) were compared to knees where tibial slope was decreased (group 2).
The average 2 year post-op ROM in Group 1 was significantly greater than that of Group 2 (129.3 degrees vs. 120.5 degrees, p=.001). The average pre-op to post-op increase in ROM in Group 1 was significantly greater than Group 2 (38.1 degrees vs.27.7 degrees, p=.003). Correlational analysis revealed that restoration of pre-op tibial slope was the primary determinant of post-op ROM, followed by pre-op ROM, then weight and BMI (each to significance of p< 0.05).
Restoration of tibial slope clearly produced increased ROM in this study. Using one standard slope cut for every tibia may prevent many patients from achieving their maximum potential ROM.
The aim of the study was to compare clinical results after cruciate-retaining total knee arthroplasty (TKA) between the ceramic and the Co-Cr alloy condylar prostheses.
In a prospective semi-randomised study, 218 patients underwent cruciate-retaining TKA with the Co-Cr alloy prosthesis (Kinemax®, Howmedica) or the LFA-I® prosthesis (Kyocera) composed of an alumina ceramic femoral component and a titaniumalloy tibial component with a UHMWPE insert. In each surgery, both components were fixed with PMMA cement. All the patients underwent the same postoperative management. Finally, 110 knees with the ceramic prosthesis and 84 knees with the Co-Cr prosthesis were followed up for 24 to 124 months (the average of 56 months).
Two revisions were performed in each group (tibial tray breakage and infection in the ceramic group, and loosening and infection in the Co-Cr group). In the remaining patients, there were no significant differences in the HSS knee score (85 and 86 points, respectively) and the ROM (112 and 113 degrees) between the two groups. In radiological evaluation, a radiolucent line was more frequently observed with the significance (p< 0.05) in the Co-Cr alloy group (9.5 %) than in the ceramic group (2.7 %).
In the mid-term follow-up evaluations, the clinical results of the ceramic TKA are equivalent to those of the Co-Cr alloy TKA. In addition, the ceramic prosthesis showed some statistical tendency of superiority to the Co-Cr prosthesis concerning the radiolucent line. These results encouraged us to conduct a long-term follow-up study on the ceramic total knee prosthesis.
The Acrobot®, an active constraint “hands-on” robotic system, gives navigation cues to the surgeon, and also assists him in the surgery, using active software constraints if he tries to depart from the preoperative plan. It has just entered clinical trials. We report the first 5 cases.
The Acrobot® system for precision total knee arthroplasty comprises the following components:
1. A CT-based planning system 2. The limb positioning system 3. The Acrobot’s hardware components:
a gross positioning device with separate brakes and encoders, locked off for safety during the procedure, a fully back-driveable low force robot, and a force control handle on the robot close to the high-speed milling tool.
4. The Acrobot’s software which:
imports the preoperative plan, allows anatomic registration provides navigation, physically assists the surgeon perform his plan
Each patient’s knee scores were monitored and postoperative CT scan was compared with the preoperative plan.
Seven robot assisted arthroplasties have been performed. No significant complications have been encountered. The Knee and Womac Scores show that the procedure is safe and comparable to conventional surgery in the early postoperative period. The envelope of error on postoperative CT scans has been within the accuracy of the method of measurement, at < 1 mm and < 10 without the outliers which haunt every clinical series.
The Acrobot® system for total knee arthroplasty has completed its preliminary trial satisfactorily. It provides a handson operation but with robotic levels of accuracy. It is suitable for conventional open surgery, but its real place will be in the arena of minimally invasive unicondylar knee arthroplasty, hip arthroplasty and resurfacing, and in the spine, where active constraint will prevent potentially dangerous surgical errors.
Most of the approaches to computer aided surgery currently in use share the need for an accurate pre-operative surgical planning to establish the optimal conditions that the surgeon should achieve using such specialised instrumentation.
The penetration of these computer-aided planning tools in the clinical practice is still limited. The systems that replicate such 2D planning are user-friendly, but lack the full three-dimensional definition of the implant position. On the contrary, systems based on CT data, which allow a fully 3D planning, usually have cumbersome interfaces. Last but not least all programs currently available are only aimed to visualise the position and orientation of the prosthetic components, presuming that the anatomical referencing is sufficient for the surgeon to decide the correctness of the planning.
The Hip-Op research project was aimed to the development of a complete surgical simulation software environment for the pre-operative planning of total hip replacement surgery. The software had to fulfil the following basic requirements: a CT-based three-dimensional planning environment; a user-friendly graphic user interface based on the Multimodal Display approach; the possibility to integrate analysis modules aimed to provide the surgeon with additional functional data; complete independence from the type of hip prosthesis or from the intra-operative instrumentation.
The graphical interface of Hip-Op is based on an innovative visualisation paradigm, which is called Multimodal display. Hip-Op represents the anatomical objects by means of multiple views, each of which simulates a different medical imaging modality familiar to the medical professional. Two analysis modules are currently integrated in Hip-Op to provide clinically relevant 3D indicators of the implant fit and fill in the host femur.
The relative motion between a prosthesis, the cement mantle and its’ host bone during weight bearing is not well understood. Using Radiostereophotogrammetric Analysis (RSA), we examined the dynamically inducible micromotion that exists at these interfaces when an increased load is placed through the prosthesis.
Dynamically inducible micromotion was measured in the femoral components of 21 subjects undergoing total hip replacement with polished Exeter stems. Two standing RSA studies were performed, at 3 and 12 months postoperatively. Firstly in double-leg stance, and secondly fully weight bearing through the operated hip.
Subjects had no signs of clinical or radiological signs of loosening at 1 year. Significant micromotion was detected at the prosthesis-cement interface at 3 months.
Similar patterns of micromotion were observed at 12 months. The prosthesis appeared to bend during single-leg stance weight bearing, however this accounted for less than half of the total observed movement.
Conventional RSA studies were conducted at 3 months, 6 months and 1 year to confirm that the implants showed normal migration patterns.
This study demonstrates that movement exists between the prosthesis and bone during cyclical weight bearing. This dynamically inducible micromotion probably occurs at the prosthesis-cement interface. It could account for the wear that is observed on the surface of retrieved secure prostheses. This may be a mechanism by which failure eventually occurs.
The Birmingham reSurfacing Arthroplasty (BSA) is a metal on metal prosthesis with no published independent clinical studies. Despite this, it is increasing in popularity, especially as an alternative to stemmed prostheses in younger patients. This study presents the 1year migration results of the BSA femoral component using Roentgen Stereophotogrammteric Analysis (RSA).
Twenty six subjects underwent a BSA, through the postero-lateral approach using CMW3G cement, with RSA marker balls placed intra-operatively. The femoral component migration was measured at intervals of 3, 6 and 12 months using the Oxford RSA system. Geometric algorhythms were used to identify the femoral component. The data was examined for distribution prior to analysis. All statistical analysis was performed using the t-test.
The data was normally distributed. The 1 year migration results of the BSA femoral component are displayed below.
All cemented implants migrate in vivo. The majority of cemented stemmed implant migration occurs within the first post-operative year. High rates of migration within the first post-operative year correlate with premature component failure in some instances. The BSA is a fundamentally different design to most cemented prostheses, despite this we know that very large migrations, those in excess of 2mm/year in any direction are generally regarded as poor indicators of long term outcome. These results suggest that the BSA femoral component is an inherently stable device as it does not migrate significantly within the first post-operative year. Only long-term independent clinical studies and continued RSA follow-up will enable a comprehensive evaluation of the device.
Limitations in the material properties of arthroplasty bearings have been a major impediment to increasing the longevity and durability of total joint replacement. These limitations most often manifest as wear debris related osteolysis and bearing failure. While these problems cause serious complications in THR and TKR, as arthroplasty is applied to the spine, such problems could become catastrophic. An ideal bearing material and design would be biocompatible, provide for restoration of normal range of motion, and be durable enough to sustain long term unrestricted high demand activities without mechanical failure, significant wear, or contribution to particulate related osteolysis. A new material, Polycrystalline Diamond Compact (PDC), appears to closely approximate the ideal bearing material for applications from large joints to intervertebral discs.
PDC is a diamond structure formed at ultra high pressure and temperature and bonded to a metal substrate. Bond strength to substrate approximates substrate tensile strength. PDC has unprecedented impact toughness and hardness, and has the lowest unlubricated coefficient of friction of any manmade contact bearing. A screening study was used to evaluate wear properties with ceramic and CoCr controls. Full prototypes were tested in a PMED hip simulator for 10 million cycles and on a spinal disc simulator for 30 million cycles.
In the screening study, PDC specimens demonstrated a significant advantage in wear over controls, whose wear rates were consistent with earlier studies. In simulator studies, the PDC specimens experienced extremely low wear at 10 million cycles (~1.0 mg per bearing surface) under austere conditions of no lubrication. In the spinal disc simulator, wear was approximately 0.3 mg at 20 million cycles under similar austere condition.
PDC’s unique material properties lend themselves to designs with thin (5 mm) acetabular bearings that provide for improved ROM and decreased dislocation risk, as well as to spinal applications where space is at a premium. Its properties of extraordinary impact toughness and high wear resistance lend themselves to arthroplasty applications which may require no undue activity restrictions, and may make prostheses available in which bearing wear and mechanical failure are no longer a factor affecting longevity.
Thirty-two percent of fractures were complicated initially: nerve injury (n=17), vascular injury (n=12) (including three cases with nerve and vascular injury), open fractures (n=7). The medial nerve was injured in most cases (n=12). Ulnar palsy was noted in four patients and radial palsy in one. Vessel injury led to abolition of the radial pulse in eight patients and the ulnar pulse in one; all resolved after reduction. Ischaemia of the hand was noted in two cases before reduction of the fracture but vascular surgery was not required.
Most of the fixations were achieved with cross pinning (percutaneous insertion in 47 patients and open surgery in 13). Despite minimal medial skin incision, ulnar nerve deficiency was observed after surgery in seven cases; four were rapidly regressive and three required surgical exploration with neurolysis. Six revision procedures were required for secondary displacement (10%).
The 26 Judet fixations led to ten secondary displacements requiring surgical revision for cross pinning. Four cases of postoperative ulnar nerve deficiency were noted: reoperation to release the nerve pinched in the fracture was required for only one patient.
The Blount technique was used in nine cases with four secondary displacements, including one related to two sites of nerve impingement.
Five cases of superficial pin tract infection which resolved rapidly and two cases of deep infection were noted in the early postoperative period.
Formation of a varus ulnar callus was noted in five cases: two required secondary surgery for correction.
For the Ottawa criteria, ankles positive for pain and at least one other criterion were: 64/77 BS, 43/47 MS, 2/2 SS, 21/21 DE and 13/13 fractures. All fractures were diagnosed at the first exam or at the 8-day exam.
The diagnostic criteria used in this study enabled correct first intention diagnosis in 129 patients with trauma. We propose ordering x-rays only for children with signs of moderate or severe sprain or pain in zone C (base of the fifth metatarsal: 8/8) or E (medial border of the foot: tarsal scaphoid fracture). For other cases (98/160) physical examination is sufficient.
A single operation was performed in 60 patients using a combined anterior and posterior approach and convex posterior CD baby instrumentation. Nine patients underwent two operations one week apart. All patients wore a corset brace for six months.
Compensating curvature: the mean Cobbe angle was 21° preoperatively and 12° at last follow-up. Complications: partial deficit of the anterior tibialis (n=1), nonunion (n=3), infection (n=1), disassembly (n=3), valgum tibia at the site of the fibular graft harvesting (n=1).
The twenty-two patients who achieved primary bone healing developed a hypertrophic graft (mean 61%, range 22 – 190%). Graft hypertrophy was not observed in the five cases requiring a secondary graft after the scintigram demonstrated lack of vascularisation. Hypertrophy of the vascularised fibular graft was more marked for lower limb reconstructions than for upper limb reconstructions..
Functional outcome was satisfactory in all cases. On the 30-point Enneking scale as modified, our patients achieved a mean 26 points (range 19 – 30).
Graft lengths varied from nine to 21 cm (mean 14 cm). Plate fixation was used in most cases. All patients wore a cast for six to twelve weeks after surgery.
Spearman’s test was used to search for correlations. Results were compared with those measured under the same conditions in a series of 32 adult knees published by Wanner.
The femoral measurements showed 27.01° anteversion with very wide variability (coefficient 46%) and no correlation with trochlear opening.
No significant differences were observed between the fœtal and adult measurements.
The radiological analysis was based on 193 AP and lateral x-rays. We measured: 1) the distance separating the superior pole of the cyst from the suprajacent growth cartilage, 2) the largest cyst diameter, 3) the greatest cyst height, 4) the thinnest cortical width facing the cyst, 5) the cyst surface area calculated exactly using surface area software and expressed as a a ratio of shaft diameter (S/d2, Kaelin index). These different parameters were compared for cysts associated with fracture or not.
Comparing the two cohorts of patients demonstrated that the following differences were significant (Student’s t test): 1) cyst width (p=0.0038): below 16 mm none of the cysts fractured. For wider cysts, there was no difference between the fracture and non-fracture cysts. 2) cortical thickness (p=0.0002); cortical thickness greater than 5 mm protected against fracture. If the cortical measured less than 3 mm, the risk of fracture was greater than 50%. 3) Kaelin index: (p< 0.0001) was directly correlated with fracture risk but no cutoff could be identified.
For an 80 – 100% risk of fracture, the cyst must have the following characteristics: width > 30 mm, height > 75 mm, cortical thickness < 2.4 mm, Kaelin index > 5.
For a 50% risk of fracture, the cyst must have the following characteristics: width > 24 mm, height > 55 mm, cortical thickness < 3 mm, Kaelin index > 3.
All patients underwent revision.
In our experience, intra-prosthetic displacement occurs more readily in patients with favouring conditions (alcoholism, muscle deficiency, psychiatric disorder, obesity) observed in six of our seven cases.
We also had a second population of twelve patients presenting persistent limping at one year with no objective cause. The same parameters were measured for this population.
During the first four years, polyethylene wear appeared to be the same in the two series. Beyond the fifth year, penetration of the alumina heads exhibited a regular mean 0.07 mm progression per year. Beyond the fifth year, penetration of the zircona heads accelerated reaching a mean 0.4 mm per year at twelve years. Mean volumetric wear of the polyethylene cups was 1360 mm3 for the zircona heads and 755 mm3 for the alumina heads. Osteolysis was seen as a defected facing the merckel and measured 2.5 cm2 for the Zir/PE couple and 0.35 cm2 for the Al/PE couple. The differences between the two series in linear penetration, volumetric wear, and osteolysis were significant (p < 0.05). The three zircona heads that were removed showed partial transformation from the tetragonal phase to the monoclinical phase (19%, 25% and 30%) and a roughened surface which was not sufficient to explain the polyethylene wear. Abnormal wear was explained more by loss of spherical shape and the greater volume of the zircona heads, probably related to a modification of the crystalline phase (change from the tetragonal to the monoclinical phase usually is associated with a 3% increase in volume). Analysis of the fingerprints left on the morse code of the zircona heads suggest the change in volume of the zircona heads was associated with a change in the contact between the morse cone and the zircona head over time. Analysis of the explanted cups showed wear with delamination in two cases. For one of the implants, the polyethylene insert was deformed exhibiting a fusion aspect corresponding to abnormal increase in temperature.
The Postel Merle d’Aubigné score was used to assess clinical outcome and all patients responded to a self administered questionnaire. Radiographically, we searched for signs of instability (tilt, displacement) and implant wear using precise digitalized measurements on successive digitalized x-rays with MetrOs software. We searched for qualitative radiological signs of bone reaction in contact with the implant.
We have used the modified Du Toit technique for C1-C2 arthodesis in four patients with rheumatoid arthritis, fracture of the odontoid, an odontoid bone, and isolated degeneration. The procedure was a first intention treatment for the patient with primary degeneration, and a second intention procedure for the others who had developed nonunion after wiring.
- type I = anterior opening fracture: 30 patients, - type II = “sawbone” fracture: 4 patients, - type III = “rasp line” fracture: 8 patients, - type IV = fractures comparable to other fractures of the vertebral column: 6 patients.
Fractures diagnosed late were four anterior opening fractures, eight “rasp line” fractures, and four “sawbone” fractures. A CT scan was obtained in all cases and an MRI in 30. Three compressive spinal extradural haematomas were diagnosed. Thirty-two patients died, 31 patients with spinal injuries due to decubitus-related complications and one by rupture of an aneurysm of the aorta.
Use of mobile materials should enable differentiating between effects related to the degenerative process and those induced by the arthrodesis.
- posterior displacement of T9 (between the vertical line and a line joining the geometric centre of T9 and the femoral heads (normal 11±5°), - tilt of the sacrum (angle between the horizontal line and a line tangent to the superior surface of the sacrum (normal 41±5°).
All patients were in Frankel class E. In compliance with the SOFCOT 1995 Symposium, the method described by Rosset and Laulin and the international classification described by Magerl were applied to pre-operative x-rays to search for the pathogenic mechanism involved. The radiological analysis was conducted on preoperative, immediate post-operative, 1-month, 3-month, and last follow-up x-rays. The course of spinal kyphosis and angular deformation of the trauma zone and the subjacent disc were analysed. In addition to the overall series, patients with limit therapeutic indications, according to the local kyphosis and trauma-induced regional angular deformation, were also studied.
Functional outcome: Sixty-six patients were reviewed with a mean follow-up of 45 months. All implantations except one were performed to achieve pain relief. The absolute Constant score improved by 20 points (from 25 to 46) with a 7-point gain for pain (3 to 10), a 20° gain for active elevation, an 18° gain for external rotation, and a 0.4 point gain for force. Pain relief was greater with total prostheses. Only five patients stated they were dissatis-fied with the outcome despite the fact that 18 reported significant persistent pain. The Constant score was analysed as a function of follow-up, size of the humeral head, and preoperative morphology of the glenoid surface. Radiological outcome: Certain loosening was recognised for one glenoid and one humeral stem. Among 52 shoulders with strictly identical radiological results, 33 exhibited deterioration either for the vault or the glenoid or both, with no effect on the Constant score.
The best outcomes were observed in joints with “centred” degeneration and cuff destruction. Preservation of a satisfactory centring of the cup avoided pain and enabled a mean anterior elevation of 1112.3° with a weighted Constant score of 90.5%.
For early excentred degeneration, preservation of the glenoid bone stock prevented perfect joint congruency leading to excessive lateralisation of the humerus: 20% of the shoulders remained painful and anterior elevation reached 68° with a weighted Constant score of 56%. Paradoxically, results were better in patients with severely excentered degeneration. “Acetabulation” of the shoulder preserved joint congruency and lengthened the lever arm of the deltoid by medialisation and lowering of the centre of rotation. Full pain relief was achieved in all such cases, with anterior elevation at 86° and a weighted Constant score at 78%.
The differences between the hemi- and inverted arthroplasty groups concerned the Constant score, which was significantly better in the inverted prostheses (65.5) than in the hemiarthroplasties (46.1), for all subscores. Active elevation was 138° for the inverted prostheses and 97° for the Aequalis prostheses (p < 0.01). Mean external rotation in position 1 was 22° for the Aequalis prostheses and 11° for the inverted prostheses (p < 0.01) with no difference in elevation rotation. These results remained equivalent and significant over time, even beyond five years.
Radiographically, there was one case with an anomalous humeral component (impaction) in the inverted group. For the inverted prostheses, there were three migrations that have not been revised to date and three partial screw loosenings. The main problem was the development of notches in the scapular column observed in 50% of the cases including 20% which reached the lower screw. For the Aequalis prostheses, the main problem was deterioration of the acromial vault observed in 50% of the cases leading to altered function.
The result of the humeral prostheses depended on the grade of necrosis. The postoperative Constant score was lower for advanced necrosis with lower scores for motion, force and pain (which was not influenced by age). At last follow-up, 31% of the x-rays revealed a significant narrowing of the glenoid-head space. The clinical outcome was significantly less satisfactory for all Constant scores. Rotator cuff tears, preoperative stiffness favoured glenoid wear. Tears of both cuff tendons led to poor outcome. Bone collapse with impaction of the head into the glenoid and medialisation of the humerus was a significant factor predictive of less satisfactory outcome.
- the familial nature of the condition in our patients suggestive autosomal dominant inheritance with variable penetration; - the rare occurrence of instability, probably due to adaptation since childhood; - hypoplasia of the tibial spines and the lateral condyle, consequence of ACL agenesia.
Comparing the natural history of ACL agenesia with that of post-trauma rupture led to certain observations:
- clinical and radiological congenital laxity is well tolerated; - degeneration appears inevitable in case of congenital anterior laxity. It occurs late, progresses slowly, slower than after traumatic rupture of the ACL; - unlike trauma-induced rupture, the lateral femototibial and femoro-patellar compartments are preserved for a very long period.
The lack of genetic studies and the familial nature of the cases reported here suggest that genetic surveys would be useful to elucidate this condition.
- posterior stabilised prosthesis with a fixed plateau, toric trochlea, cemented dome patella (n=10); - TKA with a rotating platform, 2-facet trochlae, rotatory congruent patella (n=10); - TKA with a rotating platform, 2-facet trochale, without resurfacing (n=10); - TKA with a rotating platform, hollow anatomic trochlae (n=10).
The following parameters were studied prospectively:
- pain assessed on a visual analogue scale; - clinical assessment of going up and down stairs (normal, step-by-step, with handrail); - kinematic assessment of active flexion extension (0°–120°) during which the position of the patella was measured in the three planes and the trajectory of the patella was noted in comparison with the healthy side and with the moment of the quadriceps; - efficacy of the quadriceps (Cibex).
- TKAs with a dome patella and those with an anatomic patella; - TKAs with an anatomic trochlae and those with a hollow trochlae;
This difference basically involved the patellar tilt, lateral subluxation of the patella, and especially, the patellar trajectory between 20° and 90°, the toric trochlae with a dome patella having a more anterior trajectory than the normal knee.
The clinical and functional study showed that:
- the percentage of totally pain-free femoropatellar articulations was higher for the hollow anatomic trochlae (96%) than for the three other types (75%) (p = 0.04); - the stairs function was better for all the anatomic trochlae compared with the dome trochlae (p = 0.05); - the efficacy of the quadriceps was the same for the four types of TKA.
Mean values remained unchanged for the three test times for the healthy knees. We therefore chose the preoperative values obtained for the healthy knee as the paired reference value for each patient. The values obtained for the operated knees were compared with these control values using two-way analysis of variance for paired variables.
The variation between the postoperative and last follow-up goniometry data exhibited a statistical correlation with the tibiofemoral index (p = 0.0005). If the index was less than 13°, most of the knees showed an increase in valgus (13 out of 19 knees); if valgus was greater than or equal to 13°, valgus was lost (for 12 of 19 knees).
Orthopaedic surgery (without tourniquet, anaesthesia block, mean duration 53±24 min) involved: partial resection of a toe 23%; amputation of a ray 36% (first ray one, second ray five, third ray one, fourth ray two, fifth ray six); transmetatarsal amputation 32%; resection of the metatarsal heads 4%; calcanectomy (n=1); below knee amputation (n=1); and systematic and multiple samples for bacteriology (deep soft tissue and bone tissue) and for pathology.
The peroperative bacteriology samples of the deep soft tissue and bone tissue demonstrated, in comparison with the preoperative samples, that antibiotics had sterilised only 14% of the lesions; with discordant comparison in 40%, partial concordance in 24%, and total concordance in 24%. For the diagnosis of osteitis (confirmed by histology of peroperative bone samples), the x-ray interpretations were largely confirmed (79% exact diagnosis, 87% sensitivity, false positives 12%), as were the bone scintigrams with labelled polymorphonuclears (exact diagnosis 93%, sensitivity 93%, false positives 7%).
Revision surgery was performed six months to seven years after arthroplasty. Arthrodesis was required for pain related or not to implant loosening or talar necrosis. One patient developed a major deviation of the hind foot secondary to progressive loosening. One patient developed infection early. An iliac graft was used to fill the bone defect in eight patients. An anterior plate-screw fixation was used for six patients, crossed screws for one, a tibiotalar nail for one, and an external fixator for one (with infection).
All radiograms were digitalised (Vidar VXR-12 plus) and analysed by four observers using the FootLog software which provides semiautomatic measurements. The following parameters were recorded: distance between the lateral sesamoid and the second metatarsal (LS-M2), the M1P1 angle (for the diaphyseal and mechanical axes of M1), the diaphyseal and mechanical distal metatarsal articular angle (DMAA) of M1, Meschan’s angle (M1–M2–M5), the distance between a line perpendicular to the axis of the foot drawn through the centre of the lateral sesamoid and the centre of the head of M4 (MS4–M4) (a corrective factor was introduced for the MS4–M4 distance to account for the displacement of the lateral sesamoid in hallux valgus), the M1 index = d1-D2 (length of the head of M1/MS4 – length of the head of M2/MS4), maestro 1 = d2–d3, maestro 2 = d3–d4, maestro 3 = d4–d5. The measured parameters were recorded automatically on an Excel data sheet and statistical analysis was performed with SPSS 9.0.
Hallus valgus was corrected whenever present: in three cases an osteotomy was performed alone to raise the first metatarsal followed by a plantar prosthesis. A basal osteotomy of the three middle metatarsals was performed to achieve elevation, valgisation, and shortening: for three cases a Weil osteotomy was performed.
- 82 short feet due to congenital metatarsal hypoplasia, - 3 first toe stumps (P1), - 32 post-trauma and post-surgery cases including two after resection of the metatarsal heads.
The cosmetic defect was the principal complaint in most patients (95 women), as well as complications related to wearing shoes. Pain in the forefoot resulted from biomechanical conflicts between the toes and the metatarals.
The functional objectives (walking for 31 patients, verticalisation for ten, comfort for one) were achieved in all patients except five. There was one taluseversus, one anterior subluxation of the talus, one persistent stepping. For two patients underlying neurological disorders did not allow fulfilment of the contract. There were also three cases of claw toes with moderate functional impact.
There were three true dislocations (2%): 1) a posterior dislocation on day 24 in a female patient presenting a fracture with impaction of the femoral stem; 2) a posterior dislocation on day 22 in a female patient in very poor general condition (severe cardiorespiratory failure, death at 48 hr); 3) one recurrent posterior dislocation related to major acetabular retroversion, revised at four months.
The trochanteric fractures are generally easier to diagnose and reduce, and usually heal well. The shaft fractures are more often displaced and readily comminutive, sometimes open, having absorbed the greater part of the trauma energy. These fractures heal like ordinary shaft fractures. Neck fractures are often seen in the lower portion with a vertical fracture line, with or without displacement.
Using a single centromedullary nail for the osteosynthesis of both fractures is an attractive solution. The proximal fracture must however be carefully reduced with percutaneous pins before attempting nail insertion. The postoperative period is generally uneventful. Problems may be encountered if the cervical fracture cannot be perfectly reduced, in which case two separate fixations would be preferable.
The prosthesis was implanted 15.6 days (mean) after initial trauma and included a metal-backed acetabular implant (except one case) and a bone autograft (except three cases). Complete weight bearing was authorised on day 3 postop for five patients, and at six weeks for ten; at three months for the other three.
Mean follow-up was 2.5 years. Thirteen surviving patients were reviewed clinically and radiographically. Five patients who had died were also included in the analysis using data reported by family before death.
The Postel-Merle d’Aubigné (PMA) and Harris scores were recorded. Survival curves were plotted. Radiological assessment included bone healing, status of the prosthetic assembly, presence of a lucent line or signs of loosening in the three acetabular zones described by De Lee and Charnley.
Radiologically, all fractures had healed. There were no mechanical complications and no signs of acetabular loosening.
The absence of early deaths and the low rate of intervention-related morbidity in this series of elderly patients is in agreement with a very small number of publications devoted to this topic.
Computed tomography demonstrated 15 extraosseous screws lying anteriorly to the sacral ala or in the sacral canal. These extraosseous screws were associated with neurological deficits in nine cases without a preoperative diagnosis. In six cases, the extra-ossesous screw was not associated with any postoperative deficit. In five cases, neurological lesions diagnosed after the operation were not associated with an extra-osseous screw. Twenty-six neurological lesions were reviewed at a mean follow-up of 25 months: improvement was observed in 19, no change in five and aggravation in two.
All patient were followed for at least four years. Therapeutic efficacy was assessed on the basis of clinical and laboratory findings and radiographic results. We searched for biological or bacteriological factors predictive of good outcome. The chi-square test and Fisher exact tet were used to compare population distributions and Student’s t test and Mann Whitney test to compare means.
Case report: A 66-year-old man with Paget’s disease of the hemi-pelvis developed pagetic hip deformation requiring a total hip arthroplasty performed in 1993. A Charnley-Kerboull cemented prosthesis was implanted. The medullary canal was plugged with fragments of cancellous bone harvested from the acetabulum (drill holes required to achieve rotatory stability of the acetabulum). One year later, an asymptomatic osteolytic lesion of the distal femur was identified at the level of the medullary plug. Hip function remained excellent despite extension to the distal and proximal femur. All inflammatory parameters were normal and the femoral component was not loosened. 99m-technetium scintigraphy revealed strong uptake in the pelvis but also in the distal femur under the femoral stem. Isolated femoral stem revision was performed in 1996 as a preventive measure against stress fracture. Pathology analysis of surgical specimens identified Paget’s disease (osteoclast hyperactivity, mosaic aspect of the osteoblasts. After femoral revision with a long stem and medical treatment with biphosphonates, the osteolytic lesion disappeared progressively, taking on the classical sclerous sequelar aspect of osteitis deformans. The disease remained quiescent six years after revision. Hip function remained excellent at last follow-up.
Operative method: A reconstruction method for the volar scaphotrapezoid ligament using a band of the flexor carpi radialis tendon was developed on cadaveric specimens before application in 38 patients. The 7-cm band of the palmaris longus tendon, with an intact metatarsal attachment was passed through a tunnel drilled in the distal pole of the scaphoid. The band was then pulled dorsally (correctly positioning the scaphoid) and sutured to the dorsoulnar border of the radius.
The time between surgery and the first consultation in our unit varied from three to nine years (mean five years four months). Persistent stiffness had been noted in the postoperative period with pain at joint mobilisation which worsened progressively. For the patients with chondrolysis of the wrist: the x-rays demonstrated destruction of the radius-first ray joint in one, the medio-carpal joint in four and overall destruction in two. Overall joint destruction was also observed in the elbow and shoulder patients. Search for other causes of joint destruction was negative; infection and inflammatory rheumatoid disease were ruled out. The common feature identified in all patients was joint irrigation with a chlorhexidine solution (Biseptine®).
Retrograde nailing was achieved by trepanation of the apex of the olecranon fossa. Proximal or distal locking was applied in all cases using one or more screws. Outcome was assessed with the S.O.O. criteria (1996).
Purpose : Compartment syndrome is a serious complication common to all trauma victims and may be life-threatening after fracture of the femur or require amputation after fracture of the lower leg. We report our experience with six cases and attempt to identify clinical signs suggestive of this severe complication.
For the femur fractures, diagnosis was suggested by high tension in the anterior compartment confirmed at pressure measurement: 60 and 70 mmHg. Rapid reduction in pressure was followed by signs of muscle necrosis in one patient. Aponeurotomy performed rapidly in the other patient did not prevent motor deficit involving the popliteal branches.
A supramalleolar lateral flap was used in six patients (40%), a sural neurocutaneous flap with a distal pedicle in seven (47%), and a sural neurocutaneous flap with a distal pedicle in two (13%). Seven patients (50%) had a bone graft.
Discussion Residual laxity was strongly correlated with clinical outcome: residual differential laxity less than 6 mm (threshold value) ensured a negative pivot test and 94% good results. We did not find any correlation between tunnel width and residual laxity. An overly anterior femoral position and medial meniscectomy significantly increased residual laxity. The femoral bore hole should be sufficiently posterior, 60 to 70% of the anteroposterior condylar width. Use of a synthetic reinforcement did not improve clinical or laximetric outcome in the reinforcement group; a natural plasty without synthetic reinforcement would be preferable.
Conclusion : Septic isolation wards (or a septic department) should be preserved. The orthopaedic surgeon, as a responsible actor in the fight against nosocomial infections, should in concert with the consulting hygienist, oppose purely administrative decisions.
The cryopreserved graft (femoral head bone bank) was used to reconstruct the acetabular defect. The graft was adapted to the size of the defect to fashion a congruent construct aimed at achieving primary stability. We did not use any supporting material in addition the primary osteosynthesis with one or two screws. A poly-ethylene cup was cemented in the graft. Most of the cement was applied onto the graft which was reamed to the size of the acetabulum. We retained a theoretical 6-year follow-up for review. All patients were seen for follow-up assessment using the Postel-Merle-d’Aubigné (PMA) clinical score and standard x-rays analysed according to the Oakeshott method. Kaplan-Meier survival curves were plotted taking change in status, revision for clinical failure as the endpoint.
Postel-Merle-d’Aubigné scale. For the radiographic analysis, we considered the situation of the implant after revision and possible later displacement. For the graft tissue, we studied integration in the De Lee-Charnley zones.
Two types of cups coated with hydroxyapatite were used depending on the acetabular potential for retaining the implant: 26 ATLAS press-fit cups (four screwed) and 22 Cerafit cups with Surfix anchor screws. Bony defects were filled with grains of macroporous calcium phosphate ceramic, alone or in combination with an autol-ogous bone graft (five patients) and/or an iliac bone marrow graft (24 patients). The Harris and modified PMA clinical scores were used for assessment. According to the Antonio classification, preoperative bone loss was grade II in 18, grade III in 27, grade IV in 3. We attempted to determine the percent of bone support under the cup before reconstruction. The centre of the prosthesis rotation and the interfaces with the biomate-rials were checked regularly.
A biopsy was obtained in all cases (seven under scan guidance). Six patients required complementary surgical biopsy. According to the O’Neel and Ackermann classification, the tumours were grade I in five patients, grade II in two, grade III in three. Tumour classification according to the Enneking topography was: zone I one patient, zone I and II one patient, zone I+II+III one patient, zone II three patients, zone II+III three patients, and zone III one patient. Careful search for extension failed to identify metastasis preoperatively in any patient. For six patients, tumour resection was performed without reconstruction. Resection was associated with a Pugent reconstruction in three patients. All patients were reviewed with an AP view of the pelvis and a chest x-ray.
Posterior displacement of the lateral condyle was confirmed by rotation of the patella in its longitudinal axis. The patella appeared to make a lateral translation movement to come in front of the lateral condyle at near complete flexion. It pulled the vastus medialis as is suggested by its movement around the anteroposterior axis.
Section of the anterior cruciate ligament had little effect on the observed kinetics. It limited the unlocking rotation which did not exceed 3°. At about 110° the femoral rotation reached a plateau for about twenty degrees. The computer display illustrated the movement of the condyles showing that the movement of both was influenced by the posterior thigh soft tissue. Section of the popliteal muscle clearly lessened external rotation of the cadaveric knee.
Frontal orientation of the femoral component was satisfactory in 89.4% of the knees in group 1 and in 77.1% in group 2. Sagittal orientation of the femoral component was satisfactory in 75.5% of the knees in group 1 and in 70.7% of the knees in group 2. Frontal orientation of the tibial component was satisfactory in 91.9% of the knees in group 1 and in 83.5% of the knees in group 2. The sagittal orientation of the tibial piece was satisfactory in 81.3% of the knees in group 1 and in 69.9% of the knees in group 2. Optimal implantation, considering all criteria studied, was achieved in 275 patients (49.5%) in group 1 and in 82 patients (30.8%) in group 2 (p< à.001). Ther was no difference in results between centres.
Conclusions: Complications observed with encased patellar components differ from the better known apposed prostheses.
There was a correlation between the anatomic presentation and function, especially evident for the Méary-Tomeno line which must be re-established. While we obtained spontaneous correction of the compensating frontal and sagittal deformations of the hindfoot, specific procedures were required to alleviate claw toes and equinism. It is also important to preserve the Lisfranc space and the Chopart space. The corrective capacity of tarsectomy is limited. To achieve satisfactory anatomic and functional results, tarsectomy must be reserved for moderate pes cavus involving a sufficiently mobile forefoot with moderate and reducible calcaneal varus where the primordial joints can be saved.
Patients and
Determine the contamination rate of donated femoral heads at primary arthroplasty within the Trent Region between July 1992 and July 2001. Does femoral head contamination result in an increased rate of early infection in the allograft donor?
We report the result of 49 revisions for aseptic cup loosening using freeze-dried allografts.
We assessed the results according to the primary pathology, severity of bone loss, direction of socket migration before revision, method of bone grafting, socket position, graft incorporation and socket loosening.
Patient’s mean age at revision was 56 years 8 months. At a mean follow up of 7 years and 5 months four cups have been revised for aseptic loosening. Five sockets have migrated but remained stable while six showed full demarcation but have not migrated.
The other 34 remained stable and show radiographic evidence of graft incorporation.
One of the major surgical challenges at revision arthroplasty is the management of bone stock loss in the acetabulum.
There are several options available for reconstruction; cemented sockets within thick cement mantles, custom sockets jumbo uncemented sockets, support rings and bone grafting. Slooff and others have shown good results with impaction grafting.(JBJS 80B 1998)
If one is to use bone graft, does the preparation of the graft have any effect on the graft itself? There are a number of ways bone can be presented, freeze dried, fresh frozen or frozen irradiated. Concerns have been raised that irradiated bone has an altered and weakened structure. There is a paucity of clinical results on this subject. In this study we present a series of patients using gamma irradiated bone for reconstruction.23% of the cases reconstructions secondary to failure due to sepsis.
Between 1987 and 2000 192 revision arthroplasties in 165 patients were performed with irradiated morcellised bone allograft for acetabular reconstruction. Only those patients with a minimum follow up of 24 months were reviewed. Clinical and radiological follow up was achieved in 130 hips in 115 patients. 9 patients had died at a range of 1 to 66 months after surgery. There were 23 (17%) re-revisions of the acetabular component. Of these 13 were for deep sepsis, 5 for persistent early dislocation and 4 for aseptic loosening. Of those hips revised for infection there was a 13% re-revision rate for reinfection. There was only one catastrophic failure of the graft and only three re-revisions for aseptic loosening to date.
We feel that impaction grafting of the acetabulum is a useful technique for reconstruction even when the index arthroplasty failed for sepsis. We have found no evidence to show that gamma irradiated bone performs any worse than other types of allograft bone.
It is generally agreed that in acetabular dysplasia the acetabulum lies excessively anteverted. Although this is true for the majority of hips, we have found that in some patients with dysplastic hips, the acetabulum lies unexpectedly in retroversion.
We present the early results of the Bernese osteotomy via an ilioinguinal approach performed at an U.K. district general hospital with no links to the Bernese group.
Between 1997 and 2002, 19 such osteotomies have been performed at our institution. Average follow-up is 3.2 years (range: 1–5.5 years). The male: female ratio was 1: 8.5. Average age at time of operation was 32.3 years (range 18 – 48). 14 were classified as having Severin grade 2 dysplasia and 5 as having Severin grade 3 dysplasia. The average preoperative Merle d’Aubigne and Postel score was 12.7 points (range 6 – 15). 21.1% of patients were rated as good, as 57.8% fair and 21.1% poor.
At most recent follow-up of preserved hip joints total mean score had increased to 16.3 (range 13 – 18). 26.3% of hips were graded as excellent, 58.9% as good and 14.8% as fair. The average postoperative values for the lateral centre-edge angle and acetabular index were 42.3° and 10.0° respectively which represents an average of 31.4° and 24.7° of improved lateral and loading zone coverage after osteotomy. The preoperative severity of osteoarthritis according to the criteria of Tonnis was grade 1 in 15.8% and grade 2 in 26.3%. Only one joint deteriorated sufficiently for it to be converted to a total hip arthroplasty. There was an overall complication rate of 59.9% comprised of 47.4% trivial, 10.4% moderate and 0.05% major complications. Our early results demonstrate the steep learning curve of this technically demanding operation and are encouraging.
Tumour necrosis factor-alpha is a proinflammatory cytokine that has been implicated in the propagation of inflammatory responses to bacterial infection and wear debris particles around loosened total hip replacements (THR). Individual TNF responses to such stimuli may be dictated by genetic variation. Single nucleotide polymorphisms (SNPs) at several loci within the TNF gene are associated with disease severity and susceptibility in a number of inflammatory conditions, but only a few SNPs have been screened in any one study.
14 SNPs have been identified within the TNF gene. Our unit has previously demonstrated that 5 SNPs are monomorphic in a sample group of UK Caucasians. We performed a case control study of the remaining 9 polymorphic positions (−1031, −863, −857, −376, −308, −238, +489, +851 and +1304) for possible association with deep sepsis or aseptic loosening.
All patients included in the study were Caucasian and had had a cemented Charnley THR and polyethylene cup. Cases consisted of 44 patients with early aseptic loosening (defined as that occurring within 6 years of implantation and findings at revision surgery or by the criteria of Hodgkinson et al for the acetabulum and Harris for the femoral stem) and 30 patients with microbiological evidence at surgery of deep infection. Controls consisted of 85 THRs that had remained clinically asymptomatic for over 10 years and demonstrated no radiographic features of aseptic loosening or ‘at risk’ signs as described by Wroblewski et al. DNA was extracted from venous blood and genotyped by Snapshot assay.
Genotype and allele frequencies for all SNPs were in Hardy-Weinberg equilibrium between THR controls and a random sample of UK Caucasians. The most significant associations were between the −238A (p< 0.05) and −863T (p< 0.05) alleles and aseptic loosening. A trend towards association was found between the −863A SNP and deep infection (p=0.80). The −238 A/G and −863 G/T genotypes were associated with deep infection (p< 0.05). No other significant associations were found.
Genetic polymorphism of TNF appears to play a significant role in THR aseptic loosening and possibly in deep infection. SNP markers may serve as predictors of implant survival and response to therapy such as anti-TNF treatment.
Acetabular dysplasia may present as previously undiagnosed or as a sequel to treated DDH in a young adult, with a natural history of subsequent development of early osteoarthritis.
Patients with acetabular dysplasia and a normal neck shaft angle, no significant leg length inequality and who demonstrate congruency at arthrogram are considered suitable for realignment pelvic osteotomy.
We report the results of 15 young adults who underwent a modified Tonnis triple osteotomy with a mean 21-month follow up. The modification was the ischial osteotomy being performed through a groin incision.
The only common complication was the requirement of catheterisation post-operatively (60%). There were no infections. There was 1 delayed union but no non-unions. One patient developed a deep vein thrombosis. All patients reported an improvement in their symptoms and level of activity, with a mean post-operative Harris hip score of 92. All showed an improved centre-edge angle of 28° (mean increase of 18°) and acetabular angle 37° (mean decrease of 13°).
The early results of this procedure show this to be a safe and useful option to delay the natural history of early osteoarthritis in the young adult.
Work carried out by Bennett [
This work investigates the hypothesis that the gait pattern of pre-revision THR patients has an effect on the wear, surface characteristics and material properties of the artificial hip joint, in particular the degradation of chemical and mechanical properties of the UHMWPE acetabular socket. Gait analysis is performed on patients prior to revision of a primary THR, with the retrieved socket used for subsequent analysis.
Chemical and mechanical analysis of a large number of retrieved UHMWPE acetabular sockets has shown clear structural changes, which are dependent on the length on time in-vivo. Increasing the length of time in-vivo between 2 and 20 years results in an increase in the percentage crystallinity of the UHMWPE of 12.7 %. A positive linear correlation (R2 = 0.765) between percentage crystallinity and number of years in-vivo is shown. This suggests recrystallisation of the polymer at a constant rate over time. This partial recrystallisation of the amorphous region correlates with degradation in the mechanical properties of the material. This pilot study aims to assess the effect of patient gait pattern on the chemical and mechanical degradation of UHMWPE, which will ultimately affect the clinical performance of the prothesis.
In a previous study
Aseptic loosening due to periprosthetic bone loss is a major cause of implant failure after total hip arthroplasty (THA). Interleukin 1-B (IL-1B) is thought to play a role in aseptic loosening by stimulating the activity of osteoclasts, the main bone resorbing cell type. A restriction fragment length polymorphism due to a C/T single base variation at +3954 in exon 5 of the IL-1B gene has been associated with differences in susceptibility to chronic periodontitis, a condition associated with bone loss. In this study we tested whether carriage of the C and T alleles at this site resulted in differential risk of aseptic loosening in 481 Caucasians (214 failed versus 267 radiologically intact implants) at 11.7± 4.1 years following primary cemented THA for osteoarthritis. Genomic DNA extracted from peripheral blood was genotyped using the Taqman 5′ nuclease method. Carriage rates were calculated and analysed using the 2 test.
In the intact implant group the frequency of the T allele was 0.253. The distribution of the C and T alleles was 147:105:15 (CC:CT:TT, respectively). In the failed implant group the frequency of the T allele was 0.241). The distribution of the C and T alleles was 124:77:13. The carriage rate of the T alleles in each group was 44.9% and 42.1%, respectively (odds-ratio P> 0.05). The genotype frequencies were in Hardy-Weinberg equilibrium for both intact and loose implant populations (Chi-squared P> 0.05).
Using the multivariate Cox proportional hazards model significant risk factors for loosening of both implant components included gender and age at THA (P< 0.05). However, carriage of the +3954 allele was not a significant independent risk factor for aseptic loosening (P> 0.05). Our data suggests that the IL-1B gene restriction fragment length polymorphism at +3954 does not influence the risk of aseptic loosening after THA.
Since wear and loosening of the ultra high molecular weight polyethylene is the one factor limiting the life of the arthroplasty we set out to identify factors associated with either low wear 0.02 mm/year or less, or high wear 0.2 mm/year or more.
In a group of 1092 patients, 1434 Charnley low-friction arthroplasties 190 (13.2%) showed low wear while 149 (10.4%) showed high wear. We used Chi square test to assess the significance.
The characteristics of the low wear group were: female gender (p=0.042) Rheumatoid arthritis (p= 0.014), Charnley category “C” patients (p=0.03) and varus position of the stem (p=0.003) The use of acetabular cement pressurization (p=0.07) and medialization of the cup (p=0.07) approached significance.
In the high wear group there was a predominance of males (p=0.042) with primary arthritis (p=0.006) as the underlying hip pathology, and the stem in valgus position (p=0.023). Rim position of the cup was approaching significance (p=0.07). There was no statistical significance between the two groups for revision for aseptic stem loosening or stem fracture (p= 0.49). There was a highly significant difference (p< 0.0001) between the two groups for revision for wear and aseptic cup loosening: 5.3% against 40%.
Changes in the cup geometry are sufficient to explain the increasing incidence with depth of cup penetration. There is much to be gained from the use of low wearing ceramic – ultra high molecular weight combination. Tissue reaction to the plastic particles cannot be the cause of stem loosening.
Polyethylene wear particle-induced osteolysis is a major cause of implant failure after total hip arthroplasty (THA). Tumour necrosis factor (TNF) is a pro-inflammatory cytokine that is thought to play a pivotal role in this process. We have recently shown that carriage of the −238 ‘A’ allele in the TNF gene promoter is associated with a higher rate of osteolysis after THA versus carriage of the [more common] ‘G’ allele. The aim of this study was to determine the effect of this polymorphism on TNF gene transcriptional activation in response to polyethylene particle stimulation using a luciferase reporter gene assay.
A 691 bp fragment (−585 to +106) of the TNF gene was amplified by polymerase chain reaction and directionally cloned into the PGL3.basic vector (Promega, Madison, WI). Insert sequences were checked using an ABI 377 DNA sequencer (PE Applied Biosystems, Foster City, CA). RAW264.7 murine macrophage-like cells in rapid growth phase were transfected with plasmids containing either the TNF-238G allele or the TNF-238A allele. pTK-RL (Promega), that expresses the Renilla luciferase gene under the control of Herpes simplex virus minimal promoter, was used as a transfection control. The cells were then either left unstimulated or were induced using polyethylene particles generated from a hip simulator. Lipopolysaccharide (LPS) and LTA (Lipoteichoic acid) were used as positive controls. Luciferase reporter activity was measured after 4 hours (Dual luciferase assay, Promega Corp., Southampton, U.K.) and the relative firefly luciferase activity was calculated. Results were analysed using repeated measures ANOVA.
Polyethylene particle stimulation at concentrations of 0, 1, 15, and 30mg/mL resulted in relative luciferase activities (mean (SD)) of 21.4 (2.9), 36.2 (8.2), 45.9 (11.1), and 40.7 (5.1) for the −238A allele; and 19.7 (5.0), 26.4 (8.0), 35.9 (2.3), and 32.4 (2.4) for the −238G allele (ANOVA P=0.01). LPS and LTA stimulation also resulted in increased reporter activity for −238A versus −238G (ANOVA P=0.02 and P=0.04, respectively).
The promoter allele TNF-238A results in higher levels of transcriptional activation versus the TNF-238G allele in response to a clinically relevant stimulus, and provides functional evidence for the significance of this polymorphism in the development of osteolysis after THA.
It has been proposed that scoring systems could be nationally used, initially on a secondary care level as a method of prioritising patients on waiting lists for hip and knee arthroplasty. If this were to be successful, scoring systems could be used as a way of tackling the ever increasing waiting list times for surgery which currently stand at around 15 months on the NHS.
I studied and compared the New Zealand and Oxford Hip and Knee Scores, collecting data from 79 patients over a period of seven weeks.
I found that generally, patients who scored highly were recommended for surgery; however I also found that in the group of patients recommended for surgery there was a wide range of scores obtained. There was also a great deal of overlap between the scores obtained by those who were recommended for surgery and those who were not. This means that it would be very difficult to predict a decision for an individual patient based purely on their scores. In addition, many confounding variables can affect the wide range of scores obtained.
I concluded that there was too much variation between the scores obtained by patients undergoing surgery to be able to consistently and fairly prioritise them. In order to implement the use of scoring systems in this country, nationally approved criteria and priority banding categories need to be established. Scoring systems need to be modified to be clearer and to cover more variables. Larger studies need to be conducted with more patients and over a longer period of time; and further work could be done into the proposal that GP’s could use these systems as a tool for referral to consultant out-patient clinics.
Successful treatment of the infected arthroplasty remains a major concern to the revision surgeon. We aim to present our audit of the use of the Biomet Femoral Spacer in staged revision of the infected total hip arthroplasty.
Following removal and thorough debridement of the infected joint the spacer is created using the Biomet mould and the surgeon’s choice of cement with additional antibiotics.
Custom moulding allows for the incorporation of intramedullary devices to stabilize periprosthetic fractures.
The patient is then able to mobilize non weight bearing on the spacer until infectious parameters return to normal, before the second stage is attempted.
In our series fifty cases have been identified. Two dislocations, two prosthesis fractures and three repeat second stages are noted. Examples will be presented.
We believe the Biomet Femoral Spacer has a definite role in the management of this difficult problem.
Recent studies, including the Swedish Hip Register, have confirmed that modern cementing techniques are important to achieve long-term implant survival. Their ultimate goal is to obtain an increased strength of cement and its interfaces with bone, thereby maintaining secure fixation and effective load transmission.
The objective of this study was to measure the medullary pressures generated during bone cement injection, pressurisation and femoral prosthesis insertion for total hip arthroplasty. The measurements were recorded throughout the length of an in vitro femoral model while implanting a series of prosthetic hip stems using different pressurisation techniques. The prostheses used were the Charnley 40 flanged stem, an Exeter No. 3 stem, and a custom primary femoral component used in Belfast (Johnson & Johnson, DePuy International Ltd.). The following parameters were derived from the pressure data recorded; peak pressure, decay pressure and duration above 76 kPa, the pressure regarded as the threshold to obtain adequate bone penetration.
The range of peak distal stem pressures expected for all stems was 200–500kPa. The custom and Exeter stems generated proximal cement pressures in the range 100–300kPa. These pressures were attained through cement containment by stem design or auxiliary pressurising devices, respectively. It was observed that the Charnley femoral component did not perform as well with regard to proximal pressurisation, irrespective of which pressurisation technique was implemented. The durations of pressure maintenance above 76kPa are also important, 5 seconds being accepted as a minimum for an effective interface. These results reflect the pressure measurements, with adequate durations being maintained by those stems and pressurisers that were characterised by higher peak pressures.
It is concluded that stem design and the complementary cement management techniques are essential to realise the pressure/time characteristics that are regarded as necessary to form an optimum bone/cement interface.
The use of distal femoral centralising devices has been advocated in order to achieve an even cement mantle. This has been shown to improve femoral component survival but it is recognised that the presence of voids in the mantle has a deleterious effect on the mechanical strength of cement at laboratory testing and in terms of implant survival. The effect of centralising devices on the mantle in relation to the timing of stem insertion has not previously been investigated.
The purpose of this study is to assess the quality of the cement mantle in artificial bone using a polished taper stem with centralisation inserted at different stages of cement cure time and using different cements.
Three cement types were studied, 45‘saw bone’ models were used. The cementation was carried out in an operating theatre at constant temperature of 23.2Ê°C. The cement was mixed according to the manufacturers instructions and pressurised. Early, intermediate and late stem insertion times were determined for each cement type. The late group included stems with and without centralisers. Video recordings of the stem cement interface were made with a 4 mm endoscope after stem removal. Large cement mantle defects were noted in the ‘with centraliser’ group in 7 out of 15 late insertion times and all had small defects in the mantle. None of the ‘without centraliser’ group had cement mantle defects.
Based on our results we advise surgeons to be very aware of the timing of stem insertion when using centralisers.
The Huckstep ( Bbraun Medical) interlocking hip prosthesis has been used in the Sheffield Lower Limb Arthroplasty Unit in cases of complex primary and revision hip arthroplasty since 1996. We reviewed the outcomes in cases performed prior to October 2001.
Eighty cases were identified. Of these, eight died within one year of surgery, four of which were in the peri operative period. A further thirteen were lost to follow up in the first year due to medical deterioration, move from area or refusal to attend. The remaining 57 patients had a mean time to follow up of 34 months (12–81m).
As a primary prosthesis the Huckstep was used to allow corrective osteotomy. In revision cases it was employed to bypass periprosthetic fractures and fragile proximal femoral bone, in cases requiring extended trochanteric osteotomy to facilitate cement removal, and to enable use of bulk proximal femoral allograft. The use of the Huckstep was planned pre operatively in 67 cases and as a salvage option in 13.The design of the implant allowed a stable construct without the need for bone cement which could interpose and prevent bone healing or graft incorporation. It avoids problems incurred in pressurising cement or impaction grafting against fragile bone.
Complications included infection requiring further surgery (5), dislocation (5), periprosthetic fracture (2), screw breakage (4), and mechanical failure (2). Eleven patients required further revision surgery. The apparently high complication rate reflects the complex nature of the surgery and the high degree of co morbidity in the elderly patient group.
In conclusion, we have found the Huckstep hip prosthesis to be a useful option in cases of complex hip surgery. Whilst the long term outcome is as yet unknown, our short term results show it to have allowed healing of fractures, osteotomy sites and cortical defects, allograft incorporation and replenishing of bone stock, hence facilitating further arthroplasty surgery.
Joint fluids obtained for diagnostic purposes from 25 patients were assayed for the presence of gentamicin. All of the patients had presented with failing or painful joints at periods up to 10 years following primary hip or knee arthroplasty using gentamicin-impregnated cement. Gentamicin was detected in the joint fluids from 9 of 15 patients with knee prostheses and 4 of 10 with hip prostheses. Gentamicin concentrations ranged from 0.06mg/L to 0.85 mg/L with no significant differences in concentration between patients with hip or knee prostheses, or type of prosthesis, and no identifiable relationship was found gentamicin concentration and the time after primary arthroplasty. Although the majority of the gentamicin concentrations were found to be below the levels required to inhibit susceptible pathogens, we conclude that gentamicin release around failing implants may lead to false negative cultures in some patients and provide selective pressure for the emergence of resistance where infection is present in others.
The average age of the of the patients that healed was 65.4yrs and 70.06 in those that lifted. Again this was significant (p=0.0078).
There was no correlation between sex of the patient, seniority of the surgeon or the prosthesis type with trochanteric union.
We recommend careful planning pre-operatively to limit the change in position of the trochanter.
Venous Thromboembolism is a common complication following a hip replacement. Recently the pulmonary embolism prevention study was published. It reported that aspirin decreased the fatal pulmonary embolism rate in patients admitted with a fracture neck of femur. In addition new products (synthetic factor X inhibitor -Fondaparinux, and a direct thrombin inhibiter-Desirudin) have been reported to be more effective than low molecular weight heparin in preventing asymptomatic deep vein thrombosis. We felt it was important to repeat a survey, done in 1997, on the use thromboembolism prophylaxis among British Orthopaedic Surgeons.
A single page questionnaire was sent out to all 1308 consultants Orthopaedic surgeons who were members of the British Orthopaedic Association. Those who did not respond were sent a reminder letter.
We achieved a 72% response rate. All surgeons use some form of prophylaxis. Eighty five percent of surgeons use pharmacological prophylaxis. Low molecular weight heparin is used by 55% of surgeons. Twenty percent of surgeons use aspirin as their only form of pharmacological prophylaxis. Less than 1% (5 consultants) use early mobilisation alone and nearly 2% (13 consultants) use graded stockings and early mobilisation as their only form of prophylaxis. Seventy four percent of surgeons have a unit policy. Thirty percent have changed their regime in the last 3 years.
The majority of British Orthopaedic surgeons still use pharmacological thromboprophylaxis. There has been a significant increase in the use of Aspirin from 5% to 30%. Aspirin is often combined with a mechanical prophylaxis. This has led to an increase in the use of intermittent calf compression (3% to 22%), and foot pumps (12% to 19%). Low molecular weight heparin use has fallen by 10%.
The majority of British Orthopaedic surgeons still use pharmacological thromboprophylaxis. There has been a significant increase in the use of Aspirin from 5% to 30%. Aspirin is often combined with a mechanical prophylaxis. This has led to an increase in the use of intermittent calf compression (3% to 22%), and foot pumps (12% to 19%). Low molecular weight heparin use has fallen by 10%.
In 1999 a statement of best practice in primary total hip replacement was approved by the Council of the British Orthopaedic Association and by the British Hip Society to provide a basis for regional and national auditable standards. We have compared practice in the North West of England to this document to ascertain adherence to this guide to best practice.
86 surgeons from 26 hospitals were included in the study. A mean of 93.3% of operations were performed in the surgeon’s usual theatre. All of these theatres had vertical laminar air flow systems. 42.2% of respondents routinely used exhaust suits. 68.1% of respondents routinely used impermeable disposable gowns, 26.1% used impermeable reusable gowns. The Charnley femoral and acetabular prostheses were the most commonly used prostheses.
All surgeons use some form of anti-thromboembolic prophylaxis. 66.2% use a combination of both mechanical and chemical means. All surgeons used antibiotic prophylaxis. The most popular choice of antibiotic was a cephalosporin. 70.7% used a three-dose regime over 24 hours. 2.6% of surgeons continued antibiotic prophylaxis for 48 hours after surgery. 93.7% of surgeons routinely use antibiotic-loaded cement.All surgeons routinely cleaned, irrigated and dried the acetabulum and femur before cement insertion. Only one surgeon did not use any form of femoral canal occlusion. 69.4% used an intramedullary bone block. Retrograde filling of the femoral shaft by means of a cement gun was practised by 65.1%.
This study has demonstrated considerable variation of practice in THA across the North West region and significant divergence from the statement of best practice approved by the BOA and BHS. The introduction of a properly funded national hip register will surely help to clarify the effect of such diverse practice on patient outcome. We would recommend that all trusts locally audit their practices and correlate them to these nationally agreed guidelines.
Of the 15 scans performed only 10 were found to provide an accurate diagnosis confirmed at the time of surgery, The presence of osteochondral defects, loose bodies, synovitis and AVN were all correctly identified.
Of the remaining five cases, two labral injuries were identified radiologically, but arthroscopy proved to be normal. MRI was also found to be particularly inaccurate when assessing for articular cartilage defects, failing to demonstrate moderate to advanced changes in three cases, later confirmed at surgery.
The median to follow up was 3 years (mean 3.8, range 1–8).The changes in the clinical state of the patient at the last follow up are shown in the table: At the time of the latest follow-up 74 of the cups and 69 of the stems showed definite radiological signs of osseointegration.
Resurfacing total hip replacement using metal on metal bearings is increasing in popularity, but the outcomes are currently unclear. We report a series of 23 hips in 20 patients who underwent resurfacing total hip replacement over a period of 4 years. The mean age at surgery was 47 years (21–61). There were 8 females and 12 male patients. The mean follow up was 27 months (range 6 to 50 months). Before performing this study, our impression was that most outcomes were good but that there appeared to be more variability in pain relief than anticipated after conventional total hip replacement. Most were performed for primary osteoarthritis; other diagnoses included AVN, DDH and multiple epiphyseal dysplasia. Outcomes were measured examining x rays, survival of the implant and the Oxford hip questionnaire.
There were no early revisions, but we are aware of one loose acetabular cup (in a patient with DDH) which is asymptomatic but which will probably require revision. There were no femoral neck fractures. The median score using the Oxford hip questionnaire was 15 (mean 23.5; range 12 to 41). These outcomes compare favourably with those reported at 6 months follow up after conventional total hip replacement by the Oxford group (OHQ median score 22; mean 24.3 (12 to 51)).
We conclude that resurfacing metal on metal hip replacement gives comparable results to total hip replacement at early follow up. The age of the Oxford groups patients was considerably older than ours (75 years), and a comparative trial of resurfacing versus conventional hip replacements will be required to determine which gives better short and long term results in young patients. There may be more variability in pain relief after resurfacing THR than after conventional THR, but this will require a larger study to determine with confidence.
We undertook a radiological evaluation of this technique. We assessed fracture union and strut allograft incorporation using the radiological criteria of Emerson et al. The procedure was deemed a success if the fracture had united, with evidence of graft incorporation with a stable implant. We also undertook a notes review identifying any risk factors and any previous surgery.
The Collum Femoris Preserving (CFP) total hip system is an anatomically designed, Hydroxyapatite coated, Uncemented, end bearing prosthesis, requiring minimal bone resection of the femoral neck, with an anatomical,uncemented acetabular cup. We have performed 55 Total Hip arthroplasties using the CFP Total Hip system to date. The average age of our patients is 51.5 years (13 to 65). Original pathology was Osteoarthritis in 38 hips, avascular necrosis in 9 hips and rheumatoid arthritis in 8 hips. They have all been performed by the same surgeon via a posterior approach. The Average inpatient stay has been 6.5 days.We have had one lateral femoral wall burst (requiring no intervention), one calcar fracture, and three legs lengthened, but no other complications. Pain relief is equal to conventional hip replacement. The clinical scores have been excellent Harris hip scores average 93.8% at one year. 100% have been very satisfied on post operative ratings questioning.
This prosthesis is suitable for young patients in which maximal bone conservation is required with excellent short term follow up.
In the anatomical position the tendon of this powerful muscle curls round the inferior aspect of the neck of the femur to its insertion into the greater trochanter. A component of its action is therefore one of external rotation. However in flexion the tendon eventually comes to lie parallel with the neck of the femur; it is then purely an external rotator.
During an action as when rising from a sitting posture, it is commonly thought that the head of the femur is stressed backwards so as to produce an internal rotation strain at the shaft neck junction and thereby, in a prosthetic replacement, a potentially prejudicial torque is created around the shaft of the femoral component. It is suggested that the action of the obturator externus, in particular, prevents this by converting the torque into compression along the neck of the natural femur or of a prosthesis; this is a condition which is suited to the material properties of bone in the natural state.
This paper contrives to demonstrate the evidence for the mechanism described.
Obturator externus is less frequently violated than other muscles around the hip; however, it is suggested that all of these should be carefully preserved or repaired effectively because they all contribute to a similar conversion of otherwise bending forces around the neck, to compression. In our quest to identify minutiae that contribute to long term survival of hip replacements, this may be another factor for consideration.
The mortality rate at 3 months following surgery was 4% in our octogenarian group compared to 1% (P=0.02). Mean length of hospital stay was significantly (P< 0.001) longer at 12.9 (SD 7.0) days compared to 10.1 (SD 4.7). The transfusion rate in our octogenarian group was 40% compared to 28% (P = 0.009). The incidence of deep infection was 1.4% in the older group compared to 0.5% (NS). Each group had a dislocation rate of 1%. and an incidence of DVT and pulmonary embolus that was comparable.
Hips and knees are commonly replaced joints for which several types of prostheses are available. As newer versions of the prostheses are brought in, older versions are phased out. When revision is for an isolated component failure as in, wear of acetabular cup, isolated revision of the acetabular cup is an accepted procedure. If the plan is to revise just the isolated component then that particular model of prosthesis should still be available.
In an attempt to check the availability of revision components for joint replacements we wrote to ten prostheses manufacturers enquiring the availability of prosthetic components. To have a comparison, we also wrote to eighteen leading car manufacturers enquiring about the duration and any guarantees on the availability of car spare parts.
From our survey we found that the availability of the revision implants was satisfactory in that all the prostheses manufacturers were eager to provide as much assistance as possible. The draw back is that there are no regulations to ensure the availability of these prosthetic components for any length of time after discontinuation of a particular model.
The car manufacturers are not under any obligation to provide spare parts for discontinued models. The argument put forward by some manufacturers for providing spare parts up to ten years from discontinuing the model was that “it would not reflect well on the company” if it were for any lesser length of time.
Thickness (mm)
Stiffness (Nm / Degree)
1
58 +/− 4
2
37 +/− 1
3
39 +/− 1
4
25 +/− 0.3
5
24 +/− 0.3
In the future, registration with a surgical speciality may require no more than the demonstration of core knowledge in the generality of that speciality and in the diagnosis and management of the related acute conditions. Sub-speciality training will be recognised separately. Rationalisation of referral patterns would then require that primary care practitioners are aware of these special abilities.
A questionnaire was sent to 1207 General Practitioners in the Avon, Leicestershire and Central London regions. The response rate was 86.2% (n = 1040). Views were sought on the management and referral of patients experiencing problems with existing hip replacements. These included the use of pre referral radiographs, whether practitioners would preferentially refer to a specialist hip surgeon and whether they believed that referral to a generalist could compromise patient care.
The majority GP’s arranged pre referral radiographs (84.2%). A third (34.2%) indicated that they would refer to any orthopaedic surgeon. 50.0% felt that outcome could be compromised if the patient was seen by an orthopaedic surgeon without a special interest in hip surgery.
There appears to be a need for more scientific information for GP’s and an agreed referral protocol. It is expected that rationalisation the referral system would lead to closer matching of patients needs with specialists’ abilities.
Radiographic results showed no evidence of loosening of HA coated cups, in contrast to non HA coated cups which migrated significantly in 80% of cases. Four patients with loose non HA coated cups underwent revision surgery.
Guidelines from the National Institute of Clinical Excellence (NICE) recommend comparative clinical evaluation for prostheses without long-term follow-up data and set an initial ‘benchmark’ for performance at 3 years.
Data collection for the CPS-Plus stem is on-going as part of a multi-centre prospective clinical trial. 227 patients have been recruited to the trial and 70 of these have reached 3 years follow-up.
We have reviewed the intermediate term results of 56 out of 61 consecutive Wagner revision stems implanted without bone graft. After a mean of 5 years (range 4 to 7 years) 49 out of 56 hips were graded as excellent or good based on the Harris Hip Score. The clinical result was not related to the degree of femoral bone defect prior to revision.
49 Out of 56 hips were seen to subside, but this did not affect the hip score at final review. The mean subsidence was 4.8mm (range 0 – 19mm).Only one stem showed continued subsidence after 12 months post-operatively, and this stem achieved a stable position by 24 months. All osteotomies of the femur united with reconstitution of the femoral bone stock. There was a low incidence of complications; one stem showed catastrophic subsidence within 48 hours of surgery, requiring re-revision to a larger Wagner stem. There was one sciatic nerve palsy. 3 hips dislocated on one occasion in the early post-operative period, but were stable at latest follow-up.
In conclusion, the Wagner stem can bypass major proximal femoral bony defects and achieve initial axial and rotational stability in intact diaphyseal bone. Subsequent stem subsidence does not affect clinical outcome, and proximal femoral bony reconstitution is achieved without the need for bone grafting.
In 1997 the “step-less” SL Plus (Endoprothetik, Rotkreuz, Switzerland) cementless total hip arthroplasty was introduced to our unit. During the passed 12 months, a retrospective study has been performed in order to evaluate the clinical and radiographic results of this arthroplasty. The preliminary results of the first 50 patients to have completed the clinical and radiographic follow-up have been evaluated. Of the 50 patients, 56 primary total hip arthroplasties were performed, in all cases the SL Plus stem was used. In 52 cases the cementless Doetz acetabular cup, made by the same manufacturer, was used. The other 4 acetabular components were: 2 long stemmed cementless components for developmental dysplasia, 1 standard cementless cup and 1 cemented cup, made by other manufacturers. All patients were reviewed clinically and radiographically. The mean follow-up time was 3 years, range 2 – 5 years. The mean Harris Hip Score was 90 (37 – 100). Patient satisfaction was: 98% satisfied, 2% dissatisfied (p < 0.001). Radiographic assessment demonstrated that all 52 (100%) Doetz acetabular cups osseointegrated, with 53 (95%) acetabular cups osseointegrating in total (p < 0.002). Of the SL Plus stems, 44 (79%) osseointegrated (p < 0.002). The following post-operative complications were observed: 2 dislocations, 2 superficial wound infections, 1 myocardial infarction, 1 sciatic nerve palsy and 1 deep vein thrombosis. The overall complication rate is high at 13%, but with no implant related failures. Nevertheless, the preliminary clinical and radiographic results of the SL Plus stem and Doetz acetabu-lar cup total hip arthroplasty are encouraging.
Venous stasis is identified in Virchow’s triad as one of the risk factors leading to deep venous thrombosis (DVT). Preventing or reducing stasis during the peri- and post-operative states should minimise the risk of DVT. We have investigated the efficacy of a new device (Waveform, Amtec Medical Ltd), employing electrical calf stimulation to promote venous return in patients (n=18, mean age 67.2±7.9yrs) presenting for total hip replacement arthroplasty. The device placed over the soleus muscle, offers various levels of stimulation (70–90V) at six second intervals. Duplex ultrasound imaging was used to locate and measure venous flow in the popliteal vein. Velocity measurements were recorded at three time intervals: before (baseline) and after induction of spinal anaesthesia, and finally in response to electrical stimulation. Results showed that immediately following spinal anaesthesia there was an increase in venous flow velocity from the baseline by a factor of 2 (from 9.2cm/s to 17.2cm/s). Furthermore, each activation of the electrical stimulus caused an increase in flow velocity by on average a factor of 4.4 over pre-stimulus flow (8.6cm/s to 39.8cm/s). These data compare favourably with previous observations using the Belfast calf stimulator and demonstrate the effectiveness of electrical calf stimulation as a method of preventing venous stasis in the lower limbs during surgery.
Insertion of the femoral component was associated with generating a larger microembolic load than the other phases of the operation.
Bladder catheterisation following joint arthroplasty is not uncommon but delaying catheterisation in the postoperative period until the patient is symptomatic can produce an atonic bladder due to the distension. This can prolong catheterisation and increase the risk of urinary tract infection. We prospectively determined if we could identify patients needing pre-operative catheterisation.
Nocturia was significantly more common in-patients requiring catheterisation (Kruskal Wallis P=0.04) and its combination with pre-operative symptoms of frequency, retention or incontinence increased the significance further to P=0.001.
Patient age of greater then 66 years had a 76.6% predictive value for the subsequent need of catheterisation. This further increased to 91.5% when combined with a previous history of either catheterisation or nocturia. The type of anaesthesia or the post-operative analgesia did not significantly influence catheterisation frequency.
The average delay from admission to having an operation for patients who had an echocardiogram was 6.7 days (mode 5days). Mean delay to patients having the echocardiogram was 3.2 days (mode 2 days) and the delay to theatre after the echocardiogram was 3.5 days (mode 1 day). 15/23 patients had adverse effects. All but one patient had a routine uncomplicated anaesthetic. Conclusion: 6–7% of hip fractures have an echocardiogram. Junior members of the orthopaedic team request the majority of echocardiograms without anaesthetic input. Requesting an echocardiogram causes a delay from admission to theatre of approximately 1 week. Delay is associated with adverse effects, which may have fatal consequences for the patient.
The metabolic response of trauma may mimic infection and the reliability of serological parameters for diagnosing infection may be questionable. We prospectively assessed the changes in the acute inflammatory markers, febrile response and the immune profiles cytokine activation and collagen markers of 101 patients following primary hip arthroplasty and their association with infection.
Statistical comparison of WBC, Plasma viscosity, temperature profiles and T helper,
T cytotoxic cell and NK cell assays is not different between patients with and without systemic infection or raised titres of Staph. Aureus or Staph. Epidermis. Collagen markers were significantly higher in wound complications.
An observation was made in our unit that sciatic nerve injury following total hip arthroplasty seemed to be more common in women. This observation has been mentioned in the literature, but no anatomical explanation has been postulated. We aimed to confirm this and suggest an anatomical explanation.
Members of the British Hip Society were approached by means of a postal questionnaire regarding the sex incidence of sciatic nerve injury following both primary and revision hip surgery in their practice. In this cohort of surgeons, of 179 reported sciatic nerve injuries, 77% were in women (80% in primary hip replacement and 69% in revision surgery), which is statistically significant.
We suggest that the wider outlet of the female pelvis causes the path of the sciatic nerve to pass more closely to the posterior wall of the acetabulum so making it more vulnerable to surgical injury. This hypothesis has been explored by measurements taken from CT scans of the pelvis and hips. Results do confirm the closer proximity of the nerve to the hip joint in women. We therefore advise increased care when performing hip replacement in women and suggest that this be mentioned as a gender linked risk when consenting patients prior to surgery.
Dislocation is a recognised complication following the posterior approach in total hip arthroplasty. The senior surgeons involved in this study had routinely repaired the short external rotators and capsule by directly suturing ‘tendon to tendon’ and ‘capsule to capsule’ using No 1 Vicryl®. Over a two-year period this had no impact on the incidence of dislocation as compared to “no soft tissue repair” that had been done historically. In order to assess the effectiveness of ‘soft tissue to soft tissue’ repair fifteen patients were assessed using radiographic markers inserted during surgery. In 14 of the 15 patients the repair was found to have failed by the time of the post-operative x-ray which was taken on day 3 to 5. Since then we have changed the repair so that the capsule and rotators are reattached to bone with No 5 Ethibond® using drill holes in the trochanteric region. This modification was evaluated using the same method. Of 15 patients in the second type of repair only 2 showed a failure of repair on the post operative X-ray. This appears to be a more secure form of repair. The impact of this on the incidence of dislocation is being evaluated.
Intra-operative infiltration of local anaesthetic into peri-operative tissue has become part of the protocol of many units worldwide. It is claimed that this reduces post operative pain and improves the speed of mobilisation thereby improving the comfort of the patient and decreasing the hospital stay.
In order to test the validity of this concept we conducted a prospective randomised controlled clinical trial of 100 patients undergoing primary total hip arthroplasty or hip resurfacing. All procedures were performed by one surgeon (Miss Muirhead-Allwood) using a posterior-lateral approach. Patients were randomised to receive 30ml of 0.5% Marcaine injected under direct vision at the time of closure or no injection (placebo).
Post-operatively patients in both groups received a standardised regime of intravenous infusion of diclofenac for 48 hours and ‘rescue’ intramuscular injections of morphine on demand.
Patients’ pain levels post-operatively were independently recorded using both a verbal rating score (VRS) and a visual analogue scale (VAS) at regular intervals for the first five post-operative days. Periodicity of requests for opiate analgesia was documented. Time taken to reach mobility ‘goals’ were also documented as was time taken to discharge and patient satisfaction with the whole process.
Our results show no significant difference in the two groups previously defined and we suggest that routine use of intracapsular local anaesthetic is not indicated in primary hip replacements and surface replacements provided an adequate post-operative pain regime is already in use.
In recent years there has been a resurgence of interest in the concept of hip resurfacing. Since 1996, we have treated 60 patients (65 hips) with the Corin Hip Resurfacing.
Of the 65 primary procedures, 13 have now required revision. 1 case was complicated by early deep infection and 12 (17%) for mechanical failure. 5 of these patients were male and 8 female. Mean time to failure was 11 months (range 48 hours to 53 months). 8 out of the 12 mechanical failures required revision within 6 months of the primary procedure. Mean age of the revision patients was 57 years (range 22 – 71 years).
The most common failure modality (6 cases) was fractured neck of femur. 4 out of 6 of these cases occurred in women over 60 years of age. All of these fractures occurred without a specific history of trauma. Since only 12 patients were women over 60, 1 in 3 women over 60 years of age in our series were complicated by fractured neck of femur.
In 4 cases, the indication for revision was acetabular loosening. One patient had ongoing pain of unknown aetiology and one developed progressive avascular necorsis of the femoral head with subsequent collapse.
Of the 12 cases requiring revision for mechanical failure, two cases required revision of the femoral component only and this was performed using the stemmed modular CTI prosthesis produced by Corin for this purpose. Three cases required revision of the socket only and the others were revised to total joint replacement. The one case of early deep infection was treated by two stage revision. There were no dislocations in our series and there was no evidence of metallosis.
Not for the first time in the history of orthopaedics, a DGH has been unable to repeat the excellent results reported by a specialist centre with a new technique. However, analysis of the above data has led us to believe that our results may be much improved by careful patient selection. It is also apparent that formal revision strategies need to be developed for hips resurfacing.
Low energy hip dislocation in children is an uncommon injury (0.335% of injuries ) which represents a true orthopaedic emergency.
Case 1 ; A 6 year old girl attended hospital non-weightbearing with right thigh pain after slipping whilst attempting to kick a football. The leg was shortened and internally rotated with no neurovascular deficit. Radiographs revealed a posterior dislocation of the right hip. A closed reduction was undertaken in theatre within four hours. She was immobilised in a hip spica for 6 weeks. At six month review she was pain free and back to full activities. Radiographs showed no abnormality.
Case 2 ; A 5 year old boy attended A+E non-weight-bearing with right lower leg and knee pain having done the splits playing football. Examination of knee and lower leg showed pain but nil else. Radiographs of the knee were normal. He was discharged with a diagnosis of possible ACL rupture. He re-attended 2 days later with immobility and increasing pain. Examination showed a 2cm leg length discrepancy. Radiographs revealed a posterior hip dislocation. He underwent a closed reduction in theatre. He progressed well under regular review until 5 months post-injury. He had increasing pain and decreasing range of movement. Radiographs showed trans-epiphyseal avascular necrosis. He therefore underwent a varus de-rotation osteotomy. One year on he has returned to full activities. He has a mild decreased range of movement. Radiographs show a flattened epiphysis and a united osteotomy.
Hip dislocation requires less trauma in children due to ligamentous laxity and a soft pliable acetabulum. Overall 64% are low energy and 80% are posterior dislocations. Complications include AVN, arthritis, nerve palsy and recurrent dislocation. AVN is 20 times more common if reduction is after 6 hours.
This report highlights the importance of thorough examination, accurate diagnosis and early treatment of paediatric hip dislocation.
One of the most commonly cited advantages of hip resurfacing is the technical ease of revision surgery on the femoral side of the joint. It is therefore reasonable to suggest that such surgery ought to be associated with reduced operative times, reduced blood loss and more rapid mobilisation than conventional hip revision. However, there is little objective evidence in the literature to support this view.
In our own unit, 6 consultants have now revised 15 hip resurfacings (13 Corins and 2 MMT Birmingham Hip Resurfacings). A retrospective study of the hospital records was performed to compare three well recorded parameters 1) On table operative times 2) Post Operative blood transfusion requirement 3) In patient length of stay.
Average on table time was 195 minutes for conventional THR revision and 120 minutes for revision of resurfacing i.e. a 1 third reduction in theatre time for resurfacing with attendant advantages in costs and risks. However, post operative length of stay was little different between the two groups.
Average blood transfusion requirement was 4.6 units for conventional THR revision (n=190) and 0.9 units for revision of resurfacing. However, these crude figures do not take into account the difference in physiological state between the two groups of patients. A more complex comparison of age matched revision THR patients shows and average transfusion requirement of 1.8 to 2.2 units for revision of THR versus 0.9 units for revision resurfacing.
In conclusion, there is now objective evidence of the advantages of resurfacing in the revision situation but that these advantages are more modest than those anticipated.
We report on two patient groups questioned about travelling for surgery outside of their base hospital to cut waiting times.
Firstly 30 patients travelled approximately 50–60 miles to have hip replacements. After surgery we asked them their thoughts regarding an unknown surgeon, self and relatives expenses and any inconvenience. Five (17%) were anxious about taking part and 3 (10%) incurred extra expense (transport was provided). Eight (27%) stated that relatives incurred extra expense and 5 (17%) stated relatives had difficulty visiting. All were not concerned about having their operation carried outside of the local area by a new surgeon. Asking the question as: how keen were you on having the surgical team you first met at your local hospital to do your joint replacement? responses were: 1 not keen (4%), 25 not bothered (83%) and 4 very keen (13%). Three (10%) stated that relatives had to take time off work to visit them. All patients thought that the idea of reducing waiting lists by doing the operation in a private hospital was good. We felt their response was perhaps too positive and decided to look at a local preoperative group.
Our preoperative group involved thirty patients. Four (13%) were anxious about taking part in a waiting list initiative and 10 (33%) were worried about extra expense. Seven (23%) were worried about their relatives extra expense and 6 (20%) would be discouraged if their relatives had difficulty visiting. Fourteen (47%) raised concern about having their operation carried outside of the local area by a new surgeon. Fourteen were keen to have treatment from their original surgeon. None felt that relatives having to take time off work to visit them was a problem. All patients thought that reducing waiting lists by doing the operation early in another hospital was a good idea.
We conclude that patients are accepting of waiting list initiatives if their preoperative wait can be decreased.
Resurfacing arthroplasty of the hip is currently enjoying a resurgence in popularity. There are many reasons why resurfacing may be indicated, but one is that the absence of proximal femoral reaming at surgery may reduce the occurrence of heterotopic ossification (HO) after surgery. The objective of this study was to compare the prevalence of postoperative HO for patients undergoing two different types of hip surgery, resurfacing arthroplasty or total hip replacement. Data were gathered from 43 consecutive patients undergoing metal on metal hip resurfacing (MoM-R) and 37 consecutive patients undergoing metal on metal total hip replacement (MoM-THR) with a minimum of six months’ follow up. The Brooker classification was used to grade HO from postoperative radiographs1. We found that, when undergoing MoM-R, women had a lower chance of developing HO than men (p=0.04). In addition, women who received a MoM-R had a reduced incidence of developing HO than women who received a MoM-THR (p=0.04). There were no differences in the incidence of postoperative HO between men undergoing either MoM-R or MoM-THR. It can be concluded from this study that resurfacing does reduce the incidence of HO in women and that care must be taken when selecting women to undergo total hip replacement in preference to hip resurfacing. This study has highlighted the need to inform patients of HO as a common complication when consenting for hip arthroplasty, and has established an 18% rate of postoperative HO for hip resurfacing arthroplasty.
No relationship was seen between the BMI of an individual and the development of post-operative complications. The HHS was seen to increase dramatically postoperatively in all patients (mean 43 points at 18 months). BMI did predict for a lower HHS at 6 and 18 months and a lower physical functioning score on the SF-36.
The use of rim mesh to augment acetabular defects at the time of revision hip surgery is a valuable technique. Where acetabular containment is compromised by segmental rim defects, it can be achieved by using a flexible wire mesh fixed to the wall of the ilium by multiple screws. Morsilised bone graft is then impacted onto the acetabular bed and wire mesh thus creating a new hemi-spherical acetabular bed for cementation of a new socket.
Standard AP and lateral radiographs are acceptable methods for assessing conventional socket revisions. However if a rim mesh has been used the mesh itself will obscure the socket and both columns of the acetabulum making interpretation difficult. We have modified the Judet views classically used in acetabular fracture surgery to allow better imaging of the socket. The views taken are dependant upon rim mesh position at surgery. Technique: Positioning for posterior acetabular rim mesh
From the supine position the patient is rotated 45° so that the side under examination is raised. Radiolucent pads are used to support the pelvis and leg. The hips and knees should not be flexed.
Positioning for anterior acetabular rim mesh
From the supine position the patient is rotated 45° so the non affected side is raised. Using radiolucent pads the pelvis is supported. The femur should not be flexed and externally rotated as they would be for an oblique hip
The film is centred approximately 2cm below the ASIS of the hip being examined.
These views of the hip allow complete imaging of the socket and the reconstructive construct. Radiographic evaluation of the bone graft and bone cement-graft interface can be reliably made.
We would recommend these views for the radiographic follow up of socket revisions involving the rim mesh technique.
Hull Medical Engineering (HULMEC) group was established in 1992 as a collaboration of orthopaedic surgeons and various research groups from the University of Hull to promote multidisciplinary research especially the application of computers to aid in surgery. With the joint effort of researchers and surgeons CAOSS was developed.
The key aim of the CAOSS has been to use intra-operative surgical planning using fluoroscopic based images, hence this system aids in performing those procedure which requires fluoroscopy namely dynamic hip screw guide wire insertion, distal locking of the screw and placement of cannulated hip screw. The major steps of CAOSS are the precision calibration of the fluoroscopic images, use of these images for accurate intra operative surgical planning, innovative planning algorithms, and a safe, rapid and accurate approach to trajectory execution. CAOSS has been used on the plastic bones in the laboratory setting and was found to be accurate. Presently CAOSS has been used in an ethically approved clinical trial for guide wire insertion for the DHS placement.
Perceived Advantages of CAOSS
Safe
Passive system
Non-invasive
Surgeon maintains decision making
Decreasing radiation exposure
Reducing complexity of the procedure
Reducing technical failures
Reducing operating time
Improving accuracy of implant placement
Reducing bone damage (by reducing repeated guide wire insertion)
Improving Patient outcome
Cost Effective
Easy to use
A secure bone/cement interface at the bone cement junction is an important requirement for the long-term success in the cemented hip arthroplasty. Cementing techniques have evolved and now involve pressurisation of the acetabulum and femur. It can be difficult to get a complete rim seal and hence adequate pressurisation due to the unique anatomy of the acetabulum and the contyloid notch.
Several acetabular pressurisers are commercially available.
We have developed an instrument for controlled and reproducible cement pressurisation in the acetabulum before socket insertion. It is a T-bar incorporating a central plunger, which protrudes from an outer sleeve when force is applied. The protrusion of the central plunger and hence the amount of force applied can be limited by a stop-sleeve.
A laboratory saw bone model was designed to assess this system and compare it with two existing pressurisers. A polypropylene model of the acetabulum was used. Included in the model were two 1.3mm diameter capillary outlets, one at its pole and one at a point close to its rim opposite the cotyloid notch. Water was free to flow through the capillaries at a pressure of 13.5” WG to represent blood flow. 5 test per pressuriser were performed.
CMW 1 Gentamicin bone cement was mixed as per manufacturers instruction in a Vacuum Mix system. The cement was then pressurised using one of three systems; the Depuy T handle pressuriser, the Exeter pressuriser and our new instrument.
The cement mantle produced with the Depuy T-handle and the Exeter pressuriser was thicker at the pole than the rim and the cement intrusion was not consistent nor reproducible. The new pressurizer produced a cement mantle equal at the pole and the rim to within 1mm. A reproducible cement mantle compatible to the shape of the socket and with cement intrusion of 5mm (+/− 1mm) could be achieved. We recommend the use of this pressuriser.
Hip prostheses that do not reproduce the patients’ preoperative femoral offset have been correlated with increased wear rate, instability, abductor weakness and reduced range of motion. We have reviewed the results of 54 primary low friction arthroplasties with low offset stem commonly called “¾ neck Charnley” in 49 patients (47 females and 2 males). There has been no publication in literature on the results of this stem. Mean age was 68 years (range 30 to 83). The operations were performed by one of us, (VR) as an orthopaedic trainee, with a mean follow up of 8.7 ± 2 years. The preoperative diagnosis was 40 OA, 8 protrusio, 2 DDH, 2 post-traumatic, 1 SUFE and 1 RA. The preoperative offset was 41.9 ± 7.1 mm (mean ± STD), weight 65 ± 8.4 kg, height 156.4 ± 8 cm.
At their latest review 3 cases had been revised for infection or recurrent instability with a survivorship of 93.5% using Kaplan Meyer’s analysis. None of the femoral or acetabular components were loose or at risk of loosening. 16 cups showed demarcation in 1 zone of ≤ 1mm, and 2 cups had a 2 mm demarcation in 2 zones that was not progressive. 7 stems had ≤ 1mm demarcation in 1 zone, and 5 stems at 2 zones. Condensation at the tip of the stem was noted in 2 hips. The linear wear rate was 0.2 ± 0.08mm/year. Using Pearson’s correlation coefficient with P< 0.05, no statistically significant correlation was found between the preoperative offset and the linear wear rate.
We believe that the surgeon should try to reproduce the patient’s femoral offset aiming for the best intra-operative soft tissue balance. The linear wear rate in this series is higher than previously reported in cases that survived for over 20 years from this unit. However, at this stage of analysis low offset Charnley stems produce good medium term results.
Transient osteoporosis of the hip is a rare condition of unknown aetiology affecting middle aged men with no risk factors and women in their third trimester of pregnancy. The condition invariably resolves spontaneously, however, due to its rarity and initially normal plain radiographs, the syndrome is often not appreciated early in its development, and particularly represents a diagnostic problem of differentiation from osteonecrosis.
We present a case of unilateral transient osteoporosis of the hip in a 52 year old male and a case of bilateral hip involvement in a 32 year old female in her 35th week of pregnancy. Both cases include the initial and follow-up plain radiographs, MRI and DEXA scan findings, through to symptomatic resolution.
We present a literature review of the disease and analyse the current evidence on aetiology, the problems in diagnosis and the current treatment modalities.
Patients undergoing total hip replacement (THR) often require further orthopaedic surgery including other primary lower limb joint replacements and revision surgery in their lifetime. We analysed the 10-year data of 552 patients who underwent primary total hip replacement between April 1991 and March 1992 at our institute. Data was available for all patients before the index operation. 77% of patients attended their 5-year review and 67% attended their 10-year review. 233 (42%) had had or subsequently had the opposite hip replaced. 30 patients (5%) had a knee replaced and 19 (3%) had both knees replaced. 4.4% underwent revision surgery.
Concluding, nearly half the total number of these patients will in due course require the opposite hip replaced. 13% will need another major joint surgery (ie revision or TKR). At £6138 for a primary THR and £8500 for revision THR, and the cost of radiographs (£60) and follow-up appointment (£60), the approximate cost implications on a conservative estimate are 13 million pounds. For a single surgeon undertaking 40 THRs in a single year the cost would be approximately £900,000. In addition, the surgeon in 10 years practice would create enough work to last him the rest of his working lifetime. These factors including cost implications and human resource requirements will have significant influence on future planning of health care trusts.
We report a surgical technique for arthroplasty of the deformed hip after poliomyelitis.
A fifty three year old man presented to our unit with a long-standing history of hip problems since contracting poliomyelitis at the age of two. Unusually, both of his hips were affected. He had been operated on twice for his right hip. This had left him with a deformed upper femur with significant shortening. The right hip was sub-luxed on presentation; this was due to a markedly dysplastic acetabulum.
The polio and subluxation meant his muscles were weak and stretched. Like other authors, we were keen to achieve a stable hip. The senior author felt that a fully constrained socket would carry the following disadvantages:
Reduced range of movement. It would be difficult to fit a constrained socket into the small amount of pelvic bone available. Constrained sockets are more likely to loosen.
An alternative approach, using a large diameter unconstrained metal on metal articulation, was employed; stability was achieved with the large head and the relatively small socket still preserved bone stock. The components chosen were a 52mm MMT, Birmingham acetabular resurfacing prosthetic, articulating with a 46mm chromium cobalt head. A fluted stem CAD CAM (computer aided design, computer aided manufacture) femoral prosthesis was used, as he needed to fully weight-bear from the outset, because of the weakness in his left leg.
He has a good, pain-free range of movement. This represents a novel solution for arthroplasty in hips surrounded by weakened musculature. It avoids dramatic limitation of movement whilst minimising the bone stock loss and risk of dislocation. The patient is delighted with the medium term results.
Thigh pain and periprosthetic osteolysis associated with the femoral stem, is a common complication of cementless total hip arthroplasty. Treatment of this disabling complication is difficult but usually requires revision of the femoral stem, which is a procedure not without further morbidity. We describe a solution which does not require revision and which brought about resolution of the thigh pain.
The patient was a 79 year old male who had a primary Total hip replacement (year 1998),This was revised (early 2001) to an uncemented cup (ABG type) and uncemented femoral component (Link MP stem) . He continued to experience disabling thigh pain which limited walking to only a few yards.The pain was thought to be related to concomitant paget’s disease in the Right hemipelvis and proximal femur. Rheumatology assessment and treatment with IV Pamidronate (three courses of treatment) did not produce any relief of pain and indicated a mechanical prosthesis related cause of pain. Radiology assessment was also indicating the same with osteolysis at the tip of the prosthesis.
The patient did not want a further revision procedure, but wanted relief of pain.Therfore sufgicsl intervention to treat the osteolysis with allograft ground bone introdued retrogradely via an anterior knee approach with an intercondylar pilot hole and initial supracondylar reaming. Allograft was introduced using a 5 ml syringe and impacted with a 1 cm diameter metal rod. 50 ml of ground bone was introduced and impacted forcibly with rod and hammer impaction.
The knee wound was closed in layers over 2 drains and post-op management was same as for total knee replacement, CPM and active NWB mobilization for six weeks followed by PWB, progressing to full weight bearing mobilization. Walking was free of thigh pain and walking distance was improved.
We present a case report of postoperative pain following THR, which was initially diagnosed as infection. The salutary message is that the correct diagnosis was a secondary tumour.
A fifty three year old man had a primary right total hip replacement for osteoarthritis, using an uncemented CAD CAM (computer aided design, computer aided manufacture) prosthesis with a Trilogy cup. Postoperatively he recovered uneventfully, with a normal range of movement and good function; there were no radiographic abnormalities noted at the time. Two years after operation, he developed pain in the right thigh. His doctor referred him for investigation of his back, which was normal. He was then seen by an orthopaedic surgeon who diagnosed infection, based on an X-ray that revealed a destructive lesion of the upper femur. He was referred back to the senior author, who felt that the X-ray was more suggestive of tumour than infection; further investigation, with MRI and ultrasound confirmed the presence of a tumour; isotope bone scanning revealed it to be solitary. A needle biopsy showed follicular thyroid tumour to be present; this was confirmed by immunohistochemistry. His past medical history included a history of hemithyroidectomy eight years prior to the hip replacement – this was for what was believed to be a benign thyroid nodule. CT of his chest revealed multiple lung metastases.
Review of the X-ray taken six months post-operatively suggests, in retrospect, that the destructive process had already begun. He has been treated with a total thyroidectomy and radiotherapy to the right hip with encouraging early results. He is also having chemotherapy for the pulmonary metastases. Thyroid tumours metastasise by blood and commonly occur in bone; the proximal femur is a frequent site for metastasis. It is likely that the occurrence is coincidental.
We performed a prospective clinical study in order to assess the effectiveness of repair of the short hip rotators, divided in the course of total hip replacement by the posterior approach, by the use of radio-opaque markers.
Fifteen patients, each with a diagnosis of osteoarthritis of the hip, were selected consecutively from a single surgeon’s operating list. Uncemented Duraloc® acetabular components and custom made cemented femoral components were implanted via the posterior approach in all patients.
Following implantation, the capsule and the short rotator tendons were sutured on to tendinous soft tissue around the greater trochanter using No 1 Vicryl. One radio-opaque marker clip was attached to the short rotators and capsule and a second marker was attached to the greater trochanter.
Standard antero-posterior pelvic X-rays were taken at three to five days post-operatively, and at three months following surgery. Significant separation of the radio-opaque markers in fourteen of the fifteen patients was demonstrated on the day three to five X-ray, indicating failure of the repair.
We conclude that this soft tissue repair is unsatisfactory. It may be of value to develop a more effective repair technique, with the overall aim of reducing total hip replacement dislocation, and as such we are currently investigating a soft tissue to bone repair.
No neurological deficits occurred as a result of either procedure. No subject in either treatment arm showed improvement of > 7 points in LBOS or specified domains of the SF-36. Mean ODI was 41.4 at baseline and 39.7 at 6 months for the IDET group compared to 40.7 at baseline and 41.5 at six months for the Placebo group. There was no significant change in ZDI or MSPQ scores for either group.
The anterolateral approach is a superior extension of the lateral approach used to control the VA from the C6 to C2 levels. The field is opened between the sternomastoïd muscle and the internal jugular vein. Then the VA is exposed between C1 and C2 transverse processes and above C1. It is essentially applied on extradural and bony lesions around the CCJ.
Anterolateral approach was used on 139 patients with different types of tumors including neuromeningeal tumors N=36, primary bone tumors N=51, sarcoma N=16 and others types N=21, and on 3 cases of VA compression by bone malformations. Satisfying tumoral resection could be achieved in almost all cases. Sacrifice of the VA was deliberately realized in 5 patients to ensure as radical a resection as possible in case of malignant tumors or chordomas.
There was no mortality in this series. Morbidity is very limited; injury of the VA was observed in two cases in which repair of the vessel could be done successfully. Stretching of the XI nerve was the cause of pain along the trapezius muscle in 5 patients.
CSF flow was studied at 0 and 10 minutes after injection of the CSF tracer horseradish peroxidase (HRP). Vibratome sections of the spinal cord were processed using tetramethylbenzidine and sections examined under light microscopy.
Perivascular spaces were enlarged in most cases of arachnoiditis and HRP was seen to stain these spaces and the central canal within 10 minutes.
The mean change in ASIA motor score between admission and discharge was 34.7 compared to 20.4 for the TCT group. Degree of impairment (measured by a change in ASIA Category) improved in 28% of patients and mean change in total FIM score was 41.3. There was no difference seen with the TCT group. LOS was shorter for these patients (111.1 days vs. 161.6 days). The primary means of mobility at discharge was “walking” for 50% of this group (compared to 28.4% for the TCT group) while the next most common means of mobility was “power wheelchair” at 28% (17% of TCT group). Most patients (55.4%) were discharged to their previous home following rehabilitation and 22.3% were discharged to another rehabilitation unit or acute hospital.
We wished to review the indications for surgical intervention and the outcomes in this group with emphasis on safety, rate of rehabilitation, function, and pain levels.
Questionnaires were returned by 29 of 34 patients at a mean of 3 years post-injury. All of these had returned to work or usual level of activity at 14.3 weeks (4–36 wks). Pain was experienced never or occasionally by 18 (62%), in relation to activity by 9 (31%), and on most days by 2 (7%). The average visual analog pain score was 2.1/10. No patient required regular or opioid analgesia.
Changes in equipment and technology may radically alter the paradigm used by surgeons for completing the task of an operation. An example of this is the integration of endoscopy. The hand-eye orientation, field of view, angle of approach, binocularity of vision and skew of the visual field are all altered in lumbar micro-endoscopic discectomy (MED), when compared to open microdiscectomy.
Three of the first seven cases of MED were converted to an open discectomy. None of the ensuing 18 cases was converted. The major learning outcomes to account for the change were familiarity with the radiological and videoscopic anatomy, and recognition of the importance of angles of approach.
The average time for surgery in the first ten cases was significantly longer than the second fifteen. The time for surgery in the latter group was not significantly altered from the open cohort group. The facets of surgery responsible for the increased time in the first group were techniques of exposing the nerve root, comfort of the extent of decompression of the nerve root and excision of the disc and comfort with the orientation and cleaning of the camera. The quality of illumination and visualisation of the operative field improved over the study although the significance of this could not be quantified.
Subjectively, surgeon “comfort” with the procedure developed relatively early in the “learning curve”.
There was no significant difference in clinical outcome and complications between the two groups.
Immunohistochemical analysis of each specimen was conducted using markers of apoptosis, as well as the biochemical apoptotic marker TUNEL. A total of 1800 histopathological slides were analysed. Specimens were also analysed using confocal microscopy to identify the immunopositive cell type. A combination of morphological, immunohistochemical and in situ end-labelling techniques were used to investigate the mechanism of cell death in this experiment. The analytical techniques employed were aimed at showing firstly the presence of apoptosis and secondly the size and position of the damaged regions.
There were no cases of device failure, displacement, or migration. Complications were comparable to those encountered with anterior interbody fusion.
We have demonstrated in FDI, single level fixation is biomechanically sound. Multilevel instrumentation creates loss of adjacent level motion segments. This is not necessary. The absence of a control group precludes absolute conclusions. Nonetheless most patients reported minimal disability related to their back and had excellent radiological outcomes. This study demonstrates that posterior reduction and stabilization of a single motion-segment for FDI can adequately stabilize the spine and lead to excellent functional outcomes.
Complete tumor resection was achieved in every case especially for the lateral part located into the intervertebral foramen and around the vertebral artery. Even tumors extending from the outside of the spine to the intradural space could be entirely removed through the same approach. Grafting and plating were realized in 13 out of the 126 cases of tumor.
Recent years have seen a decided swing from the longstanding inpatient model of rehabilitation to an outpatient model for all branches of medicine in Australia. This swing has been largely cost-driven and is unlikely to change. This paper reports on the development of a paediatric spinal outreach team (ORT) in NSW. The ORT was formed in 1993 and consists of a nurse, physiotherapist, occupational therapist and a social worker. It functions in close collaboration with the two children’s hospitals in Sydney. Approximately 10–11 new cases of paraplegia/quadriplegia occur in children/adolescents (up to 18 years of age) in NSW each year. Their therapeutic needs change with growth, development and maturation. Families in regional NSW have special requirements and website information services (distance education) will play an important role for them in the future. Integration with an organisation which provides ancillary services is essential for a comprehensive, state-wide program.
It is suggested that a comparable service would play an equally important role in other states. Case studies to demonstrate savings to be made with this type of service need to be done to secure recurrent government funding.
Actuarial survival rate was 80 and 65 % respectively at 5 and 10 years in group A as compared to 50 and 0% in group B. Actuarial recurrence free rate was 70 and 35% at 5 and 10 years in group A and 0% at 3 years in group B. Disease related mortality was 15% in group A and 63% in group B. The rate of recurrence per year was 0,15 in group A and 0,62 in group B. The mean delay before the first recurrence was 43 months in group A and 15 months in group B.
Factors such as sex, age, duration of symptoms, severity of symptoms, extent of tumor, histological type or grading have no influence on the survival rate and the recurrence free rate. Even the comparison between patients having received or not radiotherapy and patients treated or not by protontherapy failed to show any difference. However these groups of patients are very small and include group A and group B patients.
Complications consisted of 3 cases of minor wound drainage that settled, a possible deep infection that settled with antibiotics. There were 4 cases of transient leg weakness that recovered and one case of postoperative extradural heamatoma requiring evacuation for partial cauda equina lesion (near full recovery). Unexplained persistence of leg pain or new leg pain was present 8 cases. Three cases resolved spontaneously , 2 cases were due to screw malposition and required revision and 3 cases required re-exploration for further foraminal decompression. Other medical problems included pulmonary embolus (1), chest infection/atelectasis (2), confusional state (2), paralytic ileus (3), Atrial fibrillation (2), myocardial infarction (1).
In recent personal observations, protection by ossification was recorded in a severe trauma case and in vertebrae weakened by malignant infiltration.
The next step in this study is in the ontogenetic line of the Humans. The oldest skeleton (Ethiopia, 4.5 mya) showed “bridged vertebrae“. The first definite hyperostosis was in the Shanidar skeleton (Iraq, 40–12,000 BCE) with“flowing osteophytes”. In the historic Humans since 9500 BCE, hyperostosis was found in Europeans, Egyptians, Indians (Chile) and Incas. In the Christian era, hyperostosis was present in Roman-British/ Celt populations, Franks, Saxons, British, Swiss and N. Americans. In the 20th C, it is pandemic.
b. Impressions from the Hominid world: The ontogenetic line shows a constant presence of hyperostosis in prehistoric and historic periods. Parallel to human migration from Africa, hyperostosis expanded globally.
c. The theory of logical probability: It is postulated that hyperostosis is a condition, as no pathology (other than inflammatory) could have expanded and persisted in many species along millions of years, as it would have been removed by the rules of the Darwinian Selection. Possibly triggered by strain in younger age, functional in the past, it is today an atavistic older age “condition“, with increased osteoblastic activity in connective tissues of ligaments and tendons. At times it is incidentally discovered and is occasionally excessive. Once presented with clinical manifestations, it becomes defined an illness and should be called the Forestier-Resnick syndrome.
Stringent application of rigid selection criteria might improve outcomes in lumbar spinal fusion so that clinical and radiological results correlate more closely. However, even with adherence to such rigid criteria, the outcome tool (LBOS) may be confounded and a more holistic assessment of outcome, including a more sensitive subjective assessment of satisfaction, might be a better measure.
Science is an endeavour built on facts. Scientific methods discover facts, which have force because they are believed to be directly observable and exist independently of theory. Facts so discovered, constitute the solid and reliable foundations of scientific knowledge. Science is objective and rational because it predicts and explains outcomes that are valid and reliable. Applying scientific methods to medical practice is therefore thought to protect medical decision making from arbitrariness, bias, and error.
Pain presents a particular challenge to physicians seeking to base their practice on science. Pain is defined as an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage. It is defined as subjective, because it is an internal phenomenon, not directly observable. It represents a quality, not a fact.
Tensions arise when scientific methods attempt to include subjective experiences within its objective framework. These tensions however, must be resolved if subjective phenomena, such as pain, are to be treated in a reliable and rational manner.
This paper presents a philosophical exploration of the tensions inherent in the study of subjective phenomena, such as pain, within an objective framework, based on contemporary models of rationality.
Spinal flexion is the commonest mechanism of injury and has been associated with scrum engagement, scrum collapse, rucking or mauling, and mistimed tackling. The second most common mechanism of cervical spinal injury is hyper-extension. This commonly occurs during tackling, particularly the ‘gang tackle’ involving several participants simultaneously, where sudden deceleration of a player’s head may lead to cervical hyperextension, focal spinal stenosis and potential damage to the spinal cord by a “pincer” mechanism.
The most commonly reported levels of injury are C5/6 and C4/5 [
The code developed for this study was written in Interactive Data Language (IDL) Version 5.5 from Research Systems Inc (RSI).
Each slice from an image series was displayed to an Operator, who roughly selected the muscle(s) boundary. The user-selected points were then compared with the 24-neighbouring pixels, and the vertices moved to the minimum value in the 5x5 area, which corresponds to the muscle boundary. The adjusted region of interest was then displayed to the user for verification. Once the Operator had completed selection of the regions of interest in all slices, spatial smoothing was performed on the data, and 3D models of the muscles constructed.
The 3D model is displayed in a window that enables an operator using a mouse to rotate, scale and/or translate the model.
To aid visualisation, the volume of each muscle of interest is calculated using the number of pixels within the region of interest, pixel spacing and slice thickness. The result, in mm3, is displayed alongside the 3D model.
Nitric oxide (NO) is a free radical labile gas which has important physiological functions and is synthesised by the action of a group of enzymes called nitric oxide synthases (NOS) on L- arginine. We have shown that nitric oxide modulates fracture healing
We studied this in a novel rat intertransverse fusion model using a defined volume of bone graft (7 caudal vertebrae) along with 157 mm3 of absorbable Type-1 collagen sponge (Helistat®) carrier, which was compacted and delivered using a custom jig for achieving a similar graft density from sample to sample. The control groups consisted of a sham operated group (S, n=20), an autograft + carrier group (AC, n=28) and a group consisting of 43μg of rhBMP-2 (Genetics Institute, Andover, MA) mixed with autograft + carrier (ACB, n=28). Two experimental groups received a nitric oxide syn-thase (NOS) inhibitor, NG-nitro L-arginine methyl ester (L-NAME, Sigma Chemicals, St Louis, MO) in a dose of 1mg/ml ad lib in the drinking water (ACL, n=28) and one of these experimental groups had rhBMP-2 added to the graft mixture at the time of surgery (ACLB, n=28). Rats were sacrificed at 22 days and 44 days, spinal columns dissected and subjected to high density radiology (faxitron) and decalcified histology. The faxitrons were subjected to image analysis (MetaMorph).
On a radiographic score (0–4) indicating progressive maturation of bone fusion mass, no difference was found between the AC and ACL groups, however, there was a significant enhancement of fusion when rhBMP-2 was added (ACB group,3.3±0.2) when compared to the AC group (1±0) (p< .001). However, on day 44, the ACLB group (3.3±0.2) showed significantly less fusion progression when compared to the ACB group (4±0) (p< 0.01). There was a 25% (p< 0.05) more fusion-mass-area in day 44 of ACLB group (297±26 mm3) when compared to day 44 of the ACB group (225±16 mm3) indicating that NOS inhibition delayed the remodelling of the fusion mass. Undecalcified histology demonstrated that there was a delay in graft incorporation whenever NOS was inhibited (ACL and ACLB groups).
Our results show that the biology of autograft spinal fusion and rhBMP-2 enhanced spinal fusion can be potentially manipulated by nitric oxide pathways.
Control group consists of 30 patients treated with use of identical surgical technique but without any factors influencing blood coagulation. Fibrinogen value, prothrombine time, APTT and INR value altogether with thrombocytes count were measured day before operation and 15 minutes, two, four and 12 hours after administration of rFVII.
The use of recombinant VIIa factor shortens operation time and reduces number of blood transfusions.
This study assesses the functional outcomes and safety in a series of patients undergoing complete reduction and posterior interbody fusion (PLIF) of lumbosacral spondylolisthesis with interbody fusion spacers implanted using an Insert and Rotate technique.
Outcomes were measured using the Low Back Outcome Score (LBOS), SF-12, visual analogue pain scores (VAS) and patient satisfaction survey.
There were no deaths. There were no interbody implant / PLIF related problems but five intraoperative problems related to pedicle screw placement with one screw loosening during slip reduction, requiring replacement. Post-operatively, 3 patients developed an ileus. One patient developed a probable wound infection with high fever which settled on antibiotics.
The procedure involves, at each segment, cephalad and caudad pedicle screws connected with a polycarbourethane spacer and polyethylene cord. It achieves load relief and controlled flexion. Since 1996, 7000 procedures have been undertaken globally.
Where root compression was present, a midline approach and posterior screw placement was used in conjunction with open decompression. With back pain alone a bilateral Wiltse approach and posterolateral placement was used.
All patients were assessed pre and post surgery with SF36, Oswestry Disability Index and pain analogue scores and modified Zung. Standing radiographs were obtained post surgery and at review. Follow up was at 6, 12, 24 and 52 weeks in addition to this review.
The present series is early, but gives grounds for encouragement. Screw loosening and failure are technical problems detracting from the result and require further development.
We are continuing to use the technique.
Knowledge of the material characteristics up to 20% strain and following exposure to higher strains will enable a more realistic model of the intervertebral disc and the effects of degeneration to be studied.
Recent years have seen a decided swing from the longstanding inpatient model of rehabilitation to an outpatient model for all branches of medicine in Australia. This swing has been largely cost-driven and is unlikely to change. This paper reports on the development of a paediatric spinal outreach team (ORT) in NSW. The ORT was formed in 1993 and consists of a nurse, physiotherapist, occupational therapist and a social worker. It functions in close collaboration with the two children’s hospitals in Sydney. Approximately 10–11 new cases of paraplegia/quadriplegia occur in children/adolescents (up to 18 years of age) in NSW each year. Their therapeutic needs change with growth, development and maturation. Families in regional NSW have special requirements and website information services (distance education) will play an important role for them in the future. Integration with an organisation which provides ancillary services is essential for a comprehensive, statewide program.
It is suggested that a comparable service would play an equally important role in other states. Case studies to demonstrate savings to be made with this type of service need to be done to secure recurrent government funding.
For an antibiotic to be effective against the infecting organism it must diffuse through the disc matrix. Blood vessels that surround the disc facilitate the diffusion process, but with age this vascularity decreases and may impede diffusion.
The aims of the pilot study were to assess the effectiveness of antibiotic in treating infection in both normal and degenerate sheep discs and to measure the concentration of antibiotic in non-operated discs at varying ages.
Introduction: The Constant Score Functional Assessment (CS) is now the standard method of assessing shoulder disability in Europe. It has been observed that CS values decrease with age and attempts have been made in Canada (Constant, 1986), Germany (Tempelhof, 1999), Switzerland (Gerber, 1992) and US (Romeo, 2002) to produce national norms. Unfortunately the methods used for measuring the “Strength” category of the CS have varied. This study aimed to establish UK norms.
Methods: 200 patients stratified for age over 50 were invited to take part in this study for which Local Ethics Committee approval had been obtained. Of these 200, 46 patients (21 males) attended and all attendees had a CS carried out with the “Strength” measurement made in 3 ways – 1) maximum force using a fixed spring balance – FSB(max); 2) maximum force using a Nottingham myometer – M(max); 3) mean force from 2 to 4 seconds using a Nottingham myometer – M(mean). Results: The results for the 25 females and 21 males using M(mean) show a general trend of decreasing Constant Score with increasing age for the left and right shoulders of both the male and female subjects. There were some outliers, particularly in the female results, which were reflected in widened 95% confidence intervals. Paired student t-tests found statistically significant differences between M(mean) and FSB (max) results (left, p< 0.01; right, p=0.013) and M(mean) and M(max) (left, p< 0.01; right, p< 0.01).
Discussion: The results confirm deterioration in the CS with age in both men and women. Constant Score values from our study differ from previous studies, with up to 15 points difference between our results and those from Romeo 2002.
Significant differences were identified between the 3 methods of “Strength” measurement, highlighting the need for a uniform method of carrying out the CS. Conclusion: The UK pattern of deteriorating CS with age mirrors that seen in other countries but the values are different. These differences are significant and make it necessary to reconsider the use of the corrected CS. It is probably wiser to use the uncorrected CS but refer to normal values as a guide for the expected CS at different ages.
The aim of the present study is to compare the Oxford Shoulder Score (OSS), the Shoulder Pain and Disability Index (SPADI) and the SF36 in terms of their correlation and sensitivity to change in a group of patients with subacromial impingement.
Patients attending a specialist shoulder clinic over a six-month period with a diagnosis of subacromial impingement completed the OSS, SPADI and SF36 on each of up to four attendances at six-week intervals, regardless of treatment. The data were analysed by creating scatter plots for each scoring system compared with each other, calculation of correlation coefficients, and calculating the effect size for each scale between subsequent visits (the difference in mean score divided by the standard deviation of the change in score for all individuals). This is a measure of sensitivity to change.
Three-hundred and twenty-three sets of scores were obtained in 110 patients. Scores were recorded across the whole range of the OSS and SPADI in our population. Similarly, the physical functioning component of the SF 36 ranged from 0 to 100. However, total SF 36 scores ranged only from 478 to 831.
There was good correlation between the OSS and SPADI scores (correlation coefficient = 0.86), although in 71% of observations the SPADI score was greater than the OSS when expressed as a percentage. The correlation between the OSS and SPADI was less good with the physical functioning component of the SF 36 (0.57 and 0.51 respectively), and worse with the total SF 36 (0.37 and 0.27 respectively) The OSS and SPADI showed good effect sizes (0.211 and 0.212) compared to the physical functioning and total SF 36 scores (0.104 and 0.063).
The OSS and SPADI show close correlation between each other, and were similarly sensitive to change in a group of patients with impingement. However, the SF 36 shows a poor spread of scores and less sensitivity to change in this group. These data support the use of the OSS or SPADI in these patients.
Introduction: This study was designed to investigate which parameters of the Constant Score are most influenced by the presence of a Rotator Cuff Tear (RCT).
Methods: 28 patients attending the Shoulder Clinic took part in this study for which Ethics approval had been obtained. Strength measurements were assessed in three ways: 1) maximum force using a fixed spring balance (FSB) 2) maximum force using the Nottingham Mecmesin Myometer 3) mean force during 2nd to 4th seconds using Nottingham Myometer. The CS assessor was blind to the volunteer’s history and state of their rotator cuff. Ultrasonography was used to establish the presence of a full-thickness RCT.
Results: The CS values for the left and right shoulders were analysed separately. No statistically significant difference (p> 0.05) was found between shoulders with a RCT and without a RCT in the pain, ADL and ROM parameters. Left shoulders with a RCT scored significantly different strength scores to those without (p< 0.05) but this significance was not seen in the right shoulders (p> 0.05). Shoulder strength measurements were highest with the FSB and lowest when measured using the mean force.
Discussion: The results obtained so far suggest that a shoulder with a full-thickness tear of the RC may obtain a significantly lower strength score than a normal shoulder. It does not suggest that any of the other three parameters of the CS can indicate the presence of a tear.
Conclusion: A reduction of shoulder strength alone might be a good indicator of a full-thickness RCT. However, this study indicates the importance of standardising the method of shoulder strength assessment for the Constant Score.
87 patients (51 male, 36 female; mean age 57, range 30 to 82) underwent arthroscopic subacromial decompression (SAD) and were followed up for one year. We calculated the ASES, the Constant, the DASH Disability/ Symptom, and the SF-36 Physical Function scores.
All the scores improved throughout the follow-up period, although the SF36 score showed less marked improvement. Comparing the preoperative and one year values there were significant improvements at one year (p < 0.001) for the three upper-limb-specific scoring systems (ASES, Constant and DASH), and for the SF36, but less so (p = 0.001). Comparing the 6 months and one year scores there were significant improvements in the ASES, Constant and DASH scores, but not in the SF36 score. This suggests that improvement may still be continuing at one year.
No significant differences in the postoperative scores for the four acromion operative appearance groups (normal, minor scuffing, marked damage, bare bone areas) were found, or for the operative cuff appearance groups (normal, minor scuffing, partial tear, full thickness tear, massive cuff tear).
We also asked for the patients’ assessment of their outcome at one year, using a satisfaction visual analogue scale (VAS), and two category selection questions relating to satisfaction and to perceived room for further improvement respectively. Patients were coded as successes or failures on their responses to the VAS and the two questions. There seems to be an association with cuff appearance and success or failure as determined by the response to the room for improvement question. More specifically, this difference seems to be due the infraspinatus. A normal infraspinatus is associated with a successful outcome as perceived by the patient.
In conclusion, with SAD recovery may not be complete at one year. The three limb-specific scores are equally useful in monitoring progress, whereas the more general SF36 score is less useful. The state of the acromion or cuff does not have an effect on outcome as measured by the commonly used scores. The appearance of the infraspinatus may be predictive of success as measured by the patient.
Rotator cuff or long head of biceps tendon tears are common in patients with degenerative shoulder rotator cuff disease. Most often they are investigated with an MRI scan. Diagnosis prior to surgery is useful for the appropriate surgical planning.
We present 63 consecutive patients who had arthroscopic shoulder surgery and prior to that had MRI investigation between 1994 and 2001. Their medical records were reviewed; arthroscopic operative findings as well as the report of the MRI scan were recorded and compared retrospectively. The aim of our study was to assess the accuracy of MRI findings comparing the arthroscopic ones regarding rotator cuff and biceps tendon pathology.
There were 63 patients with mean age 58 years. All of these had MRI scan investigation and the waiting time prior to surgery was 10 months. It was found that there were 6 false (−)ve, 1 false (+)ve and two cases with full thickness cuff tears which were reported as probable tears. Further to that, there were 11 frayed biceps tendons, 8 partially ruptured, 3 subluxed, 4 complete ruptures and 1 SLAP lesion. All biceps lesions were not commented in the MRI scan reports.
MRI scan is very sensitive detecting soft tissue pathology in shoulder investigation. However, even on that basis, rotator cuff and in particular biceps tendon pathology can be missed. The shoulder arthroscopy is the best method to accurately diagnose those lesions. However, it should be noted that often the surgeon has got to alter to working surgical plan in order to address the problem intraoperatively.
In this study it is demonstrated the MRI scan often misses rotator cuff or long head of biceps tendon pathology. The most sensitive method for the diagnosis of it is the shoulder arthroscopy, which address its treatment in the same time.
A prospective study to assess the long-term outcome of ASAD (arthroscopic subacromial decompression) in the presence of un-reconstructable large and massive cuff tears using a modified Constant score.
All patients under the care of the senior author admitted for ASAD had a modified Constant score recorded pre-operatively, excluding the power component. Review of patient notes between May 1994 and August 2000 identified 40 patients (45 shoulders) with un-reconstructable rotator cuff tears found at the time of surgery. Nine patients failed to attend. Thirty-one patients (35 shoulders) were scored by a single independent observer. Five shoulders were excluded having undergone subsequent surgery. Five pre-operative scores could not be retrieved. The preoperative and review scores were compared in the remaining 25 patients (25 shoulders).
The average age at review was 75 years (range 39–85) with mean review of 51 months from surgery (range 20–94). In the studied population the mean score increased as follows (95% confidence limits in parentheses). Mean pain score improved from 4.8 (+/−2) to 8.5 (+/−1.6), the mean activities of daily living score increased from 8.9 (+/−1.5) to 12.6 (+/−2.4) and the range of motion improved from 22.9 (+/−2.9) to 31.3 (+/−3.3) points.
The total score improved from 36.6 (+/−4.6) to 52.4 (+/−6.5). The average gain for each patient was 15.8 (+/−6.5)
The 95% confidence limits indicate significant improvement for pain, range of motion and total score.
In our study population of patients undergoing ASAD in the presence of un-reconstructable cuff tears, the 95% confidence limits of the preoperative and follow up scores do not overlap. ASAD confers significant benefit in patients with large cuff defects.
Development of a novel technique of arthroscopic rotator cuff repair which adapts the proven strong open technique using the Arthrex Post (low profile screw) into an arthroscopic technique by using the Arthrex Biotenodesis screw technique. The theoretical advantages of this technique are the ability to use stronger suture material, with a simple, tolerant, knotless and adaptable technique
Prior to use of this technique on patients we required laboratory confirmation of its benefit over present techniques. We have previous experience with laboratory testing at Exeter University using a MONSANTO TEN-SIOMETER for the previous Arthrex Post system. A similar experimental model was used for this study comparing two methods of fixation:
standard arthroscopic technique with Corkscrew anchor to decorticated footprint area on fresh frozen porcine humerus. New technique with number 2 Ethibond to biotenodesis screw in metaphyseal area of fresh frozen porcine humerus
Initial results show a significant advantage of the biotenodesis technique with failure at over 1,000 N compared to 113N for a 2cm bone tunnel and 180N–600N for anchors. This shows promise for use in patients.
To determine if the surface area of partial thickness (< 50%), Bursal side tears of the cuff influence outcome following Subacromial Decompression.
Shoulder function using Constant score (CS) was recorded before and a minimum of one year after Arthroscopic Subacromial Decompression (ASD) in patients undergoing surgery for primary impingement. In patients who had partial thickness, Bursal side tears (BT), the length of the tear in its largest dimension (surface area) was measured. These patients were divided into two groups according to the tear surface area (≤9 mm and ≥10mm) .To determine whether having a BT (< 50% thickness) or its surface area affect pre and postoperative CS, t-tests were performed.
110 patients underwent ASD over a one-year period for primary impingement. 22 patients with partial thickness BT and18 patients with intact rotator cuff were included in this study. In 10 patients, the BTwas ≤9 mm (mean7mm) and in 12 patients BTwas ≥10mm(mean13mm). Statistical analysis of Pre-& postoperative Constant scores showed that, in ≤9 mm group CS increased significantly by 21.5, p=0.02, 95% CI (4.9, 38.1). CS increased in ≥10mm group by 22.8, p< 0.01, 95%(11.5, 34.1). Comparing the change in CS between these two groups with different tears size, there was no significant difference (2-sample t-test, t=0.15, 20df, p=0.88).
To determine whether having BT tear affects pre- and post-operative Constant scores, all BTs were grouped together and compared with the group of patients with intact cuff.
In the group with BTs, average Constant scores increased significantly (paired t-test,t=5.24,21df,p< 0.01) by 22.2 with 95% CI (13.4, 31.0). In the group with no tears, average Constant scores increased significantly (paired t-test,t=5.17,17df,p< 0.01) by 26.6, 95% CI (15.8, 37.5).
Comparing the levels of absolute change in Constant scores from pre- to post-operation between the two groups there is no difference in outcome between patients with a tear and those without a tear (2-sample t-test, t=1.03, 38df, p=0.31).
We conclude that ASD yields satisfactory results in patients with BTs involving < 50% thickness, irrespective of the surface area of the tear.
Rotator cuff pathology is common in orthopaedic patients. However, there are still debates about the best way of treating those patients. We present the clinical experience from our Unit.
We present 85 patients who had arthroscopic or arthroscopically assisted shoulder surgery for full thickness rotator cuff tears between 1994 and 2001. Their medical records and radiological investigations were reviewed, and the management as well as the outcome of their treatment were recorded. The aim was to review those patients and determine if optimum assessment and management was implemented to them.
There were 47 male and 38 female patients with average age 58.8 years and weight 79.9 kg, 32 of the patients reported trauma prior to their symptoms. 63 patients had MRI scan and they had average 2.6 years of symptoms and 2.4 steroid injections before their operative management. 27 patients had arthroscopic and 58 mini open rotator cuff repair. From those with recorded pain management 32 patients had interscalene block and 21 infiltration with local anaesthetic. Their average hospital stay was 1.4 and 1.8 days for the arthroscopic and mini open repairs respectively. In 69 (77.7%) patients the result was considered overall satisfactory; 8 (9.4%) patients had temporary shoulder stiffness and/or pain, which were treated conservatively with steroid injections and physiotherapy. 11 (12.9%) of the patients required reoperation, 5 from which required cuff resuturing and 4 manipulations under anaesthetic for postoperative stiffness. 3 patients (3.5%) had other than shoulder complications including CVA, chest infection, and CTS.
Rotator cuff surgery remains a challenge where often the working surgical plan is altered intraoperatively and tissue quality is of major importance for the final outcome. Arthroscopy has reduced patient’s hospital stay and rehabilitation time. However, a not durable repair, or postoperative stiffness can be a potential risk complicating the surgical result.
In this study it is demonstrated that treatment of patients with rotator cuff disease is still a challenge, time in hospital is reduced with arthroscopic management, but the overall risk for reoperation/MUA either for not durable previous repair or postoperative stiffness was still quite high (12.9%).
Use of shoulder manipulation in the treatment of frozen shoulder (FS) remains controversial. One of the purported risks associated with the procedure is the development of a rotator cuff tear. However the incidence of iatrogenic rotator cuff tears has not been reported. The purpose of the study was to assess the effect of manipulation of the shoulder on the integrity of the rotator cuff.
In a prospective study 20 consecutive patients (21 shoulders) with FS underwent manipulation of the shoulder under anaesthesia (MUA). The average duration of symptoms was 7.3 months (4–18 months). Patients were assessed pre and post manipulation using the Constant score. An ultrasound scan of the rotator cuff was performed before and at 3 weeks after manipulation.
In all patients, pre and post manipulation ultrasound scans showed the rotator cuff to be intact. At 12 weeks after manipulation all patients indicated that they had none or only occasional pain. The mean improvement in motion was 83 degrees (range, 20 – 100°) for flexion, 95 degrees (range, 20 – 120°) for abduction, 58 degrees (range, 0 – 80°) for external rotation and 3 levels of internal rotation (range 3–5 levels). These gains in motion were all significant (p < 0.01). No fractures, dislocations or nerve palsies were observed.
In conclusion manipulation under anaesthesia for treatment of frozen shoulder resulted in significant improvements in shoulder function and pain relief as early as 3 weeks after surgery and was not associated with rotator cuff tears. When performed carefully this procedure is safe and leads to early improvements in pain relief, range of movement and shoulder function.
A previous study done in our unit showed good results in terms of union, stability and function following 2-suture repair of proximal humeral fractures. Healing took place usually with a mild degree of varus angulation but one failure of this technique when the fracture slipped into varus prompted us to re-evaluate our technique. The addition of a third (lateral) suture to the repair has been used as routine following this.
A prospective series of 24 patients with displaced Neer 2 and 3 part proximal humeral fractures was studied. The patients were reviewed at a mean of 22.5 months post fixation. The patients were reviewed clinically and graded according to the Constant Shoulder Score to assess range of movement, power, function and pain. This was compared to the contralateral uninjured shoulder.
Radiographic evaluation of fracture union, avascular necrosis and malunion was performed, and any complications of treatment were noted.
There were 24 2- and 3-part fractures. All the fractures united with no radiological evidence of avascular necrosis. At follow-up there was a mean Constant Score of 71.05 compared with a mean score of 84.5 on the uninjured contralateral shoulder. Active abduction of > 120° was achieved in 9 patients. Intraoperative stability in the varus/valgus plane was noted to be better.
All patients were satisfied with the results; the problem of instability in the coronal plane has not been a problem and the fractures have healed with no varus mal-union. There have been no additional complications with this technique compared to the 2-suture method.
We have successfully achieved stability after open reduction and suture fixation of 2- and 3-oart fractures of the proximal humerus. Following one case of varus instability using a 2 suture technique,
We have routinely supplemented this with a third (lateral) suture. There have been no additional complications using this method, the angulation of the fractures once healed are improved and none of the repairs have had a problem with varus slip.
To identify any shoulder joint pathology on MRI of young patients (< 35 yrs) with a single simple antero- inferior dislocation of the shoulder at minimum 5-year follow-up.
Patients aged 16–35 years with a single antero-inferior shoulder dislocation with a minimum 5-year (range5–9 yrs) follow-up were identified. A history of recurrent dislocation or surgery excluded patients from study. Ethical approval was obtained and identified patients were asked to volunteer for clinical review and have an MRI scan. Shoulders were clinically examined, noting specifically any signs/symptoms of rotator cuff pathology or instability. All shoulders were imaged with a 1.5 Tesla open MRI scan to assess any pathology.
In a 5-year period (1994–1998), 349 patients sustained an antero-inferior dislocation. 251 were in patients aged 35 years or less. 136 of these were excluded either due to recurrent dislocations. 62 patients were lost to follow-up of 53 eligible patients 7 could attend for study. Only one patient had a positive anterior apprehension sign but he did not have any symptoms of instability in his daily activities or sport. The only abnormality demonstrated on MRI was of a united greater tuberosity fracture in one shoulder. The glenolabral and bicipitolabral complexes were normal in all shoulders imaged.
Bankart lesions, both bony and labral, are known to be associated with recurrent anterior shoulder dislocations.This study has shown no shoulder joint pathology on MRI at minimum 5-year follow-up in young patients who have sustained a single antero-inferior shoulder dislocation, confirming that labral pathology seems to be important in recurrent dislocations. Further study to image more patients is underway. These results indicate that acute imaging of dislocated shoulders may be useful to help predict young patients who are unlikely to re-dislocate and thus unlikely to require surgery.
To discover how traumatic anterior shoulder dislocation in the young patient (17–25) is managed by shoulder surgeons in the UK.
A comprehensive postal questionnaire was sent to 164 orthopaedic consultants, all members of BESS. Questions were asked about the initial reduction, investigations undertaken, timing of any surgery, preferred stabilization procedure, arthroscopic or open, detail of surgical technique, period of immobilization and rehabilitation programmes instigated in first-time and recur- rent traumatic dislocaters.
The response rate was 82% (n=135)
The most likely treatment of a young traumatic shoulder dislocation:
It will be reduced under sedation in A&
E by the A&
E doctor. Apart from x-ray, no investigations will be performed It will be immobilised for 3 weeks, then given course of physiotherapy Upon their second dislocation, they will be listed directly for an open Bankart procedure (with capsular shift as indicated) during which subscapularis will be detached and metallic bone anchors used Following surgery, they will be immobilised for 3 to 4 weeks, before being permitted full range of movement at 2 to 3 months and allowed to return to contact sports at 6 to 12 months
On the other hand, 54% of surgeons indicated they would investigate prior to surgery, 18% said their first choice operation would be arthroscopic stabilisation, the number of dislocations normally permitted before surgery ranged from 1 to more than 4, and the period of immobilisation post operation from nil to 6 weeks.
We now know how shoulder surgeons in the UK are treating this common injury. The results reveal that in Britain, we do not have a consistent approach, raising many discussion points. Open stabilisation remains the firm favourite. Does this mean arthroscopic stabilisation is regarded as an experimental procedure?
Arthroscopic shoulder surgery is evolving rapidly and several methods of stabilisation have been described. We present a simple new technique which addresses both the Bankart lesion and the capsular stretching together with the short-term results.
The technique can be performed using just one anterior working portal and one posterior viewing portal. The labrum and capsule are elevated from the anterior glenoid neck by sharp dissection. One suture anchor is placed at the half past four position. One suture limb is passed under the labrum at 6 o’clock, the other limb is passed under the labrum at 2 o’clock and the two ends are tied. This has a purse string effect, tightening the capsule in only the superior/inferior plane, which also creates a bumper of labrum at the anterior glenoid rim.
This technique was used in 35 patients (36 shoulders) with recurrent antero-inferior instability due to a traumatic Bankart lesion. The patient group included 33 men and 2 women with mean age 25 years (16–49). They had sustained an average of 5 dislocations per shoulder (1 to 11). The cohort included 4 professional and 6 semi-professional sportsmen all of whom were involved in collision or overhead sports. All the patients were assessed by an independent investigator at an average of 14 months (6–48) post surgery.
Only one patient developed recurrent instability. This occurred without sustaining trauma. The average postoperative Rowe score was 93 (55–100), Walch-Duplay score was 93 (70–100), and Constant score was 97 (77–100). 65% of patients returned to the same level of sports and all the professional athletes were able to resume full activities.
In conclusion, this technique is simple in concept, straightforward to perform, and demonstrates excellent short-term results.
To assess the functional outcome after open shoulder stabilisation a retrospective study was performed with patients undergoing modified Bankart repair for traumatic shoulder instability.
47 consecutive patients were selected from theatre records over a five-year period who underwent open shoulder stabilisation under a single operator. 38 of these were successfully contacted by telephone (80% response) for functional assessment using two questionnaires – Oxford and Disabilities of the Arm, Shoulder and Hand (DASH). Of these patients 22 agreed to undergo examination for the Constant and Walch-Duplay shoulder scoring systems. The Constant score included measuring strength of pull using the Nottingham myometer. The average follow-up period was 31.3 months (6–60months) and return to work and/or sport was the focus of the study.
The results from the Oxford and DASH questionnaires showed that 30 patients (79%) had returned to work, 6 patients (16%) were unemployed for reasons other than their shoulder and only 2 (5%) had put their shoulder as the reason for being unable to return to work. 13 patients did no sport out of choice so of the remaining 25, 22 patients (88%) had returned to their chosen sport. The study revealed that 2 patients suffered recurrent dislocation. The results of the Constant and Walch-Duplay scoring averages were encouraging – 91.5% and 85% respectively. Only 2 patients scored below good or excellent grading. These outcomes compare favourably to other studies. A criticism of the Walch-Duplay scoring system is that it is strongly orientated towards sports activities. Our results showed a significant variation in outcome between individuals and it may be that such a scoring system is not applicable in an inner city population as studied here.
The effect of shoulder instability after traumatic dislocation can be devastating on the lifestyle and work of an individual. The Bankart repair has been shown in the literature to be successful in stabilising the shoulder joint with a low rate of recurrent dislocation and minimal loss of range of movement. However the gold standard for a successful repair must ultimately be a return to premorbid function, in particular, work and sport. This study reveals a high rate of return to work and sport after a short period following open shoulder stabilisation using a modified Bankart repair.
This study investigates the survival (with gross radiological loosening) rates of prostheses following uncemented Total Shoulder Arthroplasties (TSAs) focusing on the glenoid baseplate fixation.
All uncemented TSAs inserted in one shoulder unit from 1989 to 2001 were entered onto a database prospectively and the patients monitored to death or failure of the implant, resulting in revision surgery. Over 80% of the surviving implants were monitored on sequential radiographs and the radiological loosening rate was observed. 273 TSAs have been monitored – 193 with a porous coated glenoid baseplate and 80 with a hydroxyapatite coating on top of the porous coating.
The Survival rates (%) of the non-HA coated base-plates at 1 to 12 years using the Life Table Method were:- 97, 93, 89, 83, 83, 81, 79, 79, 77, 75, 75 & 75% respectively. The Survival rates for the HA coated glenoid baseplates at 1 to 4 years were 100, 97, 93, & 93% respectively. Failures were predominantly due to mechanical loosening and glenoid disassembly with only 3 cases of infection documented. Thus by 4 years there was a statistically significant improvement in survival of the glenoids. Survival rates were further reduced when radiological loosening was taken into account. The earlier series was analysed to assess the survival of prostheses inserted for RA and OA. The survival rates at 5 & 10 years were 78% & 70% for OA and 96% & 88% for RA.
This Life Table analysis confirms the early benefit from the use of hydroxyapatite coating of the glenoid implant of a TSA. Further improvements, particularly in relation to reducing further the small risk of disassembly are underway.
Avascular necrosis (AVN) of the humeral head is an extremely disabling condition (Gerber et al, JSES 1998. 7(6):586–90). The results of stemmed arthroplasty for this condition are good, with Hattrup and Cofield reporting 79% subjective improvement at nine years (JSES 2000;9:177–82). This study reports the outcomes of surface replacement shoulder arthroplasties for AVN over a 16 year period. Between 1986 and 2001 twenty-seven arthroplasties were performed in patients with advanced avascular necrosis of the humeral head. All patients had secondary degenerative changes. AVN was secondary to corticosteriods and trauma in most cases.
The mean age of the patients was 60 years (range 35 to 86). These included 16 hemiarthroplasties and 7 total shoulder arthroplasties. All prostheses were of the Copeland Surface Replacement Arthroplasty (CSRA) type.
The average follow up period was 6 years (range 1 to 13). The average preoperative Constant score was 17. This improved to 74 at follow-up. Forward flexion improved from 63 degrees preoperatively to 133 degrees at follow-up. Abduction improved from 49 degrees to 118 degrees. External rotation improved from −3 degrees to 61 degrees. Pain scores improved from 0 to 11.7, using a 15 point visual analogue scale. 81% of patients had slight and no difficulty performing their routine activities of daily living. The remaining 19% still had some difficulty with routine activities. Four of the patients performed regular overhead activity and recorded some difficulty in doing this, whereas they had great difficulty pre-operatively. There were no cases of loosening. No difference was seen in any of the results between the hemi-arthroplasty and total shoulder replacement patients.
Surface replacement arthroplasty is a suitable procedure for degenerative disease secondary to AVN of the humeral head, with results similar to stemmed prostheses. It has the advantage of preserving bone stock.
To measure any observed differences in migration and rotation between keeled and pegged glenoid components using roentgen stereo-photogrammetric analysis.
Between 2000–2001 in a prospective randomised study, 20 patients with osteoarthritis had a TSR with roentgen stereo-photogrammetric analysis. Five tantalum markers were introduced into the scapula and acromion, spaced widely apart. Another 4 markers were placed in either a pegged or keeled glenoid component.
RSA radiographs were taken postoperatively, three, six, twelve and eighteen months. The radiographs were digitised and analysed using dedicated software (UmRSA). The relative movement of the glenoid with respect to the scapula was measured.
The largest translation for the keeled components was in the proximal/distal direction with a mean of 1.3mm, the pegged group mean was 0.27mm. This difference was significant, P = 0.001. Both other translation axes showed no significant difference between the two component types. Medial/lateral migration gave means of 0.38mm(keel) and 0.52mm(peg) and the anterior/ posterior translation with means of 0.54mm(keel) and 0.41mm(peg). Maximal total point motion mean values at 18 months were 2.6mm for keeled and 1.1mm for pegged glenoid components. This difference was also significant P=0.001
The largest rotation was anterior/posterior tilt with means of 3.5°(keel) and 1.1°(peg) this difference was significant p=0.005; varus/valgus tilt with a mean of 3.2°(keel) compared to 20(peg) was again, significant P = 0.002. and finally anteversion/retroversion means were 3.3°(keel) and 2.7°(peg). Multivariate analysis identified 2 principal components from the keeled data each accounting for 35% of the variation in the data. The first included transverse and saggital translation together with rotation about the longitudinal axis; the second component consisted of translation on the longitudinal axis with rotation about the transverse axis.
Between 1992 and 2000, 120 shoulder arthroplasties have been inserted in patients with osteoarthritis at this hospital. Shoulder function was assessed using the ASES patient self-evaluation form and the Constant-Murley clinical index as well as evaluation including routine measurements of shoulder motion and pain. The mean follow-up was 4.4years (2 to 10years).
Movement, pain and both shoulder function scores significantly improved after operation with t-test values significant at P< 0.001 level. Three sub-groups of primary osteoarthritis (OA), avascular necrosis (AVN) and post traumatic arthritis (PTA) were analysed separately. Although each group was significantly improved after arthroplasty the AVN and PTA patients had significantly poorer results than OA patients for pain and the functional scores, except the AVN group for the Constant Murley score. General linear model analysis indicated that both Constant-Murley and ASES shoulder function scores were shown to be sensitive to change after treatment and that improvement was maintained for up to 8 years post-operation.
Kaplan-Meier analysis showed a significant difference in survival between the 3 sub-groups of OA, PTA and AVN with 5 of 16 PTA operations needing revision. This was reflected in function measurement with PTA values 20 points lower in both clinical (P=0.014) and self assessed functional status (P=0.004).
At each visit a true AP radiograph was taken. Radiological lucency was graded using the method of Matsen. The humeral components were inserted without cement and there were no signs of loosening. Just four components had lucency at one of 7 zones. There was a noticeably higher incidence of glenoid lucency, Proportional hazards analysis was used to model the hazard rate of glenoids at risk. A hazard model for the glenoid components consisted of only one variable – presence or absence of glenoid erosion noted at operation. The model is significant (P= 0.02) with erosion having a hazard rate 6 times greater than that if not eroded.
The Copeland shoulder arthroplasty has been reported to give good results over a 5 to 10 year follow-up period. In this series all the humeral implants were inserted without cement. There was evidence of radiolucency in 30% of the humeral components.
In our unit since 1995 we have implanted the Copeland shoulder hemiarthroplasty using cement around the stem of the prosthesis. We radiologically reviewed 40 patients with a mean radiological follow-up of 4.5 years. There was radiological evidence of loosening in 5%.
Of this group, twenty-five patients had a minimum follow-up of 5 years, with a radiological loosening rate of 8%.
We would suggest that the use of a small amount of cement around the stem of the humeral component is beneficial in reducing the rate of loosening.
We also feel that, as the amount of cement is small and only around the stem, if revision is required it can be undertaken without the difficulties usually associated with cemented prostheses.
The purpose of this study was to analyse the reason for failure of shoulder arthroplasties performed for osteoarthritis, looking specifically at factors associated with either hemi or total shoulder replacement.
Over an eight-year period over 80 consecutive patients undergoing a Global hemi-arthroplasty or total shoulder arthroplasty were looked at. All patients underwent at least two years of follow up. All patients were assessed pre and post operatively using the Constant and ASES scoring systems. A bio-engineer or physiotherapist performed these evaluations. X-rays were analysed for demarcation, loosening and glenoid erosion. Failure was defined as the need for revision surgery. Reasons for revision were predominately pain, loosening and instability. In these instances the differences between hemi and total joint arthroplasty were recorded. A distinct pattern was present with several early revisions being performed for continuing pain in the patient group who underwent hemi-arthroplasty.
In conclusion, this study supports total shoulder replacement as the operation of choice, in suitable patients, as compared to hemi-arthroplasty. This would appear to reduce the risk of the need for early revision on account of pain. This must be weighed against the potential for late glenoid loosening.
The composition and morphology of the glenoid are integral to the support of a glenoid component in total shoulder arthroplasty (TSA). This study was performed to identify the morphology of glenoid cavity in pre and post replacements in a cadaveric model.
Eleven normal cadaveric shoulders (Right – 5, Left – 6) were dissected down to the bone such that the glenoid labrum was left intact. Computerised Tomography (CT) scanning at 0.5 mm thickness was performed on each of the specimens in a standardised fashion to evaluate the morphology of the glenoid and glenoid medullary cavity. CT scanning was repeated after a mixture of cemented pegged and keeled glenoid components were inserted into all the specimens using standard instrumentation.
Five reproducible lengths (Body width), Posterior wall length, Anterior Wall length. Glenoid body length and corrected body width) and the retroversion angle of the glenoid were identified on the CT scans. These measurements were taken at the 25th, 50th and 75th percentiles of the height of each glenoid both pre and post replacements. Further post glenoid replacement CT scans were analysed for cement-fill of the glenoid cavity and cortical encroachment of the prosthesis.
There was significant correlation of all the measurements including the retroversion angle between the pre and post glenoid replacements at all levels. All but one pegged prosthesis had insufficient cement mantle or critical penetration or abutment at one of the pegs at least. Most often the penetration or cortical abutment was along the posterior wall. All keeled prosthesis had a sufficient cement mantle all around.
The designs of the glenoid prosthesis were satisfactory with some respects like radius of curvature, size and to a certain degree the shape. The margin of error for insertion of the pegged prosthesis was very narrow. Design changes are required in the glenoid component for better bony fixation.
One of the major long term problems of total shoulder replacement is loosening of the glenoid component. Since 1997 we have been using atmospheric pressure to drive cement into the interstices of the glenoid trabecular bone by lowering the intraosseous pressure. This is achieved by introducing a wide bore needle into the base of the coracoid process and attaching it to surgical suction. During this period approximately 200 Tornier Aequalis shoulder replacements were performed by the senior author. For the purpose of this detailed study 20 consecutive cases were studied.
Good exposure of the glenoid is achieved using an extended approach and aggressive surgical releases. The surface is prepared according to the manufacturers recommendation. The base of the coracoid is now exposed and drilled with a 3.5mm AO drill bit, angled so as not to collide with the keel of the glenoid component. A Verres needle is hammered into the glenoid at this point and connected to a separate, second suction apparatus, placed on high suction during final lavage, cement insertion and cement curing. Blood and lavage fluid can be seen to be sucked from the glenoid during preparation and cementation.
Standard true antero-posterior radiographs were taken by the same experienced radiographer in the plane of the glenoid face two days following surgery, and at 3 months and one year. A Mitotoyu digital microcalliper with a resolution of 0.1mm was used to determine the depth of cement intrusion and presence of lucent lines. Three independent observers measured each radiograph. Analysis of interobserver error shows agreement between observers. For assessment the glenoid was divided into five zones – Superior flange; superior slope of keel; base of keel; inferior slope of keel; inferior flange.
No patient had a complete lucent line around the glenoid component. Four patients had a single zone lucent line (ranging from 1.1mm to 1.7mm) None of these patients had a lucent line around the keel, and those four areas of lucency under the superior or inferior flange were more likely due to incomplete removal of articular cartilage than a failure of cement technique.
The reported prevalence of glenoid lucent lines varies from 22% to 89%. The significance of glenoid lucent lines is controversial but several studies have reported a direct relationship between the presence of radiolucent lines and the development of loosening of cemented components.
Secure cement technique is more difficult in the shoulder than in the knee or hip. Access is tighter, bleeding more difficult to control and peroxide should not be contemplated because of close proximity of the axillary nerve to the glenoid. Classic socket pressurisers can not fit into such a small space. We have found that the second sucker technique is extremely effective in establishing a secure cement-bone interface during glenoid replacement.
The coraco-acromial ligament (CAL) is partially resected during a subacromial decompression. Clinical studies have reported the regeneration of a structure which appears to be a new CAL. Histological studies of regenerated CAL have demonstrated an abundance of relatively acellular collagen fibrils orientated in the line of a ligament and mechanical testing of the regenerated tissue has properties similar to those of normal CAL. However it is still not clear whether this structure represents scar tissue or truly reformed ligament. Defining the major collagen constituent of this regenerated tissue would allow the distinction between ligament and scar tissue. Therefore the aim of this study was to examine the level of expression of types I and III collagen in regenerated coraco-acromial ligaments (CAL) in humans.
Samples of regenerated CAL were obtained during open surgery for repair of small rotator cuff tears at an average of 24 months (range 14 to 52) after arthroscopic subacromial decompression from 4 men and 3 women with an average age of 58 years (range 44 to 68). A standard protocol radio-active in-situ immunolocalisation technique was used to quantify the ratios of mRNA collagen I to collagen III in the samples.
The results demonstrated that the average ratio of collagen I to collagen III was 6.5. This ratio is similar to the value for normal hip capsule (5–6:1) and human posterior cruciate ligament (8:1).
We conclude that the reformed CALs are ligamentous structures, not scar tissue, and therefore represent truly regenerated ligaments.
The Nottingham Hood is a polyester soft tissue reinforcement device for the treatment of weakened or torn rotator cuff tendons (RCTs). The device was introduced in 1987 and has undergone a number of modifications from a close weave polyester modified aortic vascular graft (Mark 1) to an embroidered trefoil shape (Mark 4 – Pearsall’s Ltd) which has now been available since 2000. While this device has been under development it has been used on a named patient basis for 10 years on humanitarian grounds as an alternative treatment option for patients with massive RCTs. Approximately 30 Nottingham Hoods have been inserted over the past 10 years. This study investigates the histological changes and ingrowth associated with this device.
Four patients who have had the Nottingham Hood inserted for massive RCTs have had re-operations for various reasons on five occasions. Excised material from the rotator cuff has been subjected to histological investigation. Excised biopsy material has been obtained 6 weeks, 6, 9 & 12 months and 14 years following implantation. Transmitted and polarised light microscopy has been used in all cases.
At 6 weeks birefringent clear material similar to suture material was identified, invested by fibrin and occasional red cells i.e. old thrombus. The fibrin was partly calcified and insinuated between bundles of the meshwork material. No true ingrowth of material was seen at this stage. At 6 months the material was seen macroscopically to be covered with collagenous material, rather like fascia which interdigitated closely with the embedded polyester material. At 14 years the mesh appeared to be invested, sandwich-like into a collagenous fascia-like structure with dense hyaline bands of collagen. Some fibrin was also present between the fibrils and a low grade foreign body giant cell response with light chronic inflammation. The local synovium showed detritic synovitis.
The histological features show that there is an early organisational response to the insertion of the new tissue, which is then accompanied by long-term incorporation into host tissues by fibrosis and scarring. A small fibrin and foreign body response lingers on.
This long-term follow-up assessment provides evidence that long-term implantation of polyester as reinforcement for the rotator cuff tendons is not associated with serious biological problems. However the problem of stretching of the repaired rotator cuff muscles does occur and needs to be considered in more depth.
The scapulo-humerothoracic rhythm, which can be described by up to 12 spatial variables, is either responsible for, or affected by the genesis of shoulder pathology and trauma, and therefore, imaging the articulations of the shoulder through a global range of motion is desirable in aiding the diagnosis and management of both movement deficiency and osseous lesions.
4 control volunteers were seated between the toroid of the scanner and maximally slewn table on a customised tripod. The subjects were asked to carryout a sequence of defined movements, each over a period of 5 seconds. These included adduction to abduction in the scapular plane, internal rotation to external rotation at 0° and 90° abduction and flexion to extension. An EBCT C300 scanner was used with a multislice sequence imaging protocol to collect 8 transaxial slices per volume by sweeping an x-ray beam sequentially over 4 tungsten target rings and recording x-ray intensity via two fixed detector rings after the reflected beam passes through the body, enabling the acquisition of 20 volumes per movement with minimal radiation exposure. Each slice was post-processed by semi-automatic segmentation using Amira software, and reconstructed to produce three-dimensional reconstructions. Following this, a kinematic description of the joint complex was developed using SIMM, enabling quantification of up to 5 Degrees of Freedom at the Glenohumeral joint.
EBCT provides a quick and efficient method for direct real-time dynamic imaging of the shoulder girdle, although currently crude. As such, we hypothesis the ability of EBCT to image traumatic disruption to shoulder rhythm, and are currently pursuing this work. These reconstructions promise great potential for further clinical experience and quantitative analysis of small translations aided by achievable limited technological refinement of the modality.
The aim of the study was to determine the value of clinical assessment in the diagnosis of SLAP (Superior Labral Anterior Posterior) lesions of shoulder.
A retrospective clinical review of 48 patients who underwent arthroscopic stabilisation for SLAP (Snyder Type II to Type IV) lesions between 1997 and 2003 was undertaken. The patients were assessed preoperatively by the senior author using a combination of clinical tests including Neer’s impingement test, anterior apprehension test, compression rotation test, O’Brien, Speed, Gerber and Yergason tests.
The mean age of the patients was forty-four. Thirty-nine patients had persistent shoulder pain after injury. Seventeen were sport related. Pre operative diagnosis of SLAP was made in only eleven cases. We found the Neer impingement test positive in twenty-one, anterior apprehension test in twenty-six (sensitivity 54%), O’Brien test in twenty-three (sensitivity 48%), Compression rotation test in six and Speed’s test in five patients.
Our study does not support any single or combination clinical tests that can diagnose SLAP lesions with confidence. In a young patient with persisting shoulder pain after injury, positive anterior apprehension test should alert suspicion. Arthroscopic examination remains the most reliable assessment of the damaged labrum.
Tennis elbow (lateral epicondylitis) is a common upper limb condition, possibly resulting from angiofibroblastic degeneration. Conservative treatment comprises corticosteroid injections, rest and splints, however, occasionally surgery is necessary.
Recent data comparing Botulinum Toxin Type A (BTX-A) (Botox®, Allergan Inc, Irvine, CA) with surgery suggested BTX-A is effective in treating resistant tennis elbow by providing temporary, reversible paralysis of affected muscle, thereby alleviating tensile forces and allowing tissue healing.
This double-blind, randomised, controlled trial compared BTX-A with placebo in 40 patients with chronic tennis elbow (> 6 months). Recruited patients were randomised to 50U BTX-A+2mL normal saline or 2mL normal saline (placebo). Injections were administered 5cm distal to the maximal area of lateral epicondyle tenderness. Quality of life (SF-12), pain (visual analogue scale) and grip strength (Jamar dynamometer) were assessed pre- and 3 months post-injection in both affected and non-affected arms. Following BTX-A treatment patients had average 19% improvement in grip strength in the affected arm compared to average 2% for placebo, however, this difference did not reach statistical significance (p=0.08, 95% CI −2.31, 35.64). No difference between the groups was seen for the unaffected arm (BTX-A 4% improvement, placebo 1% improvement).
Both groups showed similar improvements in pain assessment and also in quality of life.
BTX-A treated-patients demonstrated improved grip strength in the affected arm compared to placebo, however this difference was not statistically significant.
To ascertain the effect of the site and number of loose bodies on the functional outcome of Outerbridge-Kashiwagi (O-K) procedure in management of osteoarthritis of the elbow.
12 patients were reviewed after having O-K procedure, and assessed using Mayo Elbow Performance score, and radiographs assessed using Derby Elbow Osteoarthritis Radiography score.
There were 10 male and 2 female patients with mean age of 47 years. The mean follow up was 24 months. In 8 (66%) patients the diagnosis was primary osteoarthritis, and 4 (34%) had post-traumatic arthritis. Nine (75%) patients had osteoarthritis of the dominant elbow, and three were non-dominant. Nine patients had locking and catching symptoms. 7 patients had < 2 loose bodies, and 5 had > 2 loose bodies. 7 had anterior loose bodies alone and 5 had both anterior and posterior loose bodies.
The Mayo Elbow Performance score improved from a mean preoperative value of 51 to 85 points postoperatively (p< 0.0001). There were 3 excellent, 7 good, 2 fair, and no poor results. Visual analogue pain score improved from a mean of 7.4 to 2.6 postoperatively (p< 0.001). The Derby Elbow Osteoarthritis Radiography score improved from preoperative mean of 6.5 to 5.3 postoperatively (p< 0.013). There was no significant difference between functional outcome of primary osteoarthritis and post-traumatic arthritis (p> 0.42). Number of loose bodies had no significance on the functional outcome (p> 0.39), neither did the site of the loose bodies (p> 0.44). There was no significant difference of the number of loose bodies on the overall total score of Derby Osteoarthritis Elbow Score (p> 0.2). In two patients revision had to be undertaken due to persistent locking that improved postoperatively.
The number and site of loose bodies, the type of osteoarthritis and the duration of symptoms have no significant prognostic value in predicting functional outcome
The purpose of the project was to develop a questionnaire for completion by patients with elbow pathologies which is short and practical, internally consistent, valid, responsive and sensitive to changes of clinical importance.
The first, pilot phase included 43 patients who each completed a 19 item questionnaire relating to elbow function. The 19 ADLs produced a total scale Cronbach Alpha of 0.96., two different groups of ADLs were identified by multivariate analysis. Group 1 consisted of ADLs requiring moderate to high isometric loading and Group 2 of ADLs requiring high flexion. From the 19 items the best 10 which represented both groups were selected. A summary score was used to create the Wrightington Elbow Disability Score (WEDS).
In the second phase 89 patients completed the new WEDS form, reliability studies produced a Cronbach’s alpha value of 0.91. Internal validity of the groups of ADLs all correlated at p< 0.001 level with strength (Group1) and flexion (Group 2). A sub set of 40 patients undergoing total elbow arthroplasty were assessed for sensitivity to change in disability, the WEDS indicated a significant improvement at the p< 0.001. Convergent validity was demonstrated by the correlation with the ASES-e score at p< 0.001 level. The WEDS was significantly correlated with the ASES-e but not the DASH score.
Our study confirms that the WEDS questionnaire which is short and practical, is internally consistent, valid, responsive and sensitive to changes of clinical importance.
Although it is generally accepted that revision total elbow replacement may be necessary for loosening, instability, peri-prosthetic fracture and infection there is less agreement as to whether surgery should be performed as a one or two stage procedure. This can be of vital importance since the soft tissues around the elbow are often relatively poor making a single operation desirable. However, a one stage procedure in the presence of undetected low grade infection will result in joint failure with early loosening.
In our unit we have found the use of a preliminary aspiration/drill biopsy prior to revision surgery helpful in evaluating whether a one or two stage procedure should be performed.
Over an 8 year period 18 revision total elbow replacements have been undertaken. 9 patients were revised for aseptic loosening, 4 for proven infection, 3 for instability of an unlinked implant and 2 for peri-prosthetic fracture.
With this experience we have devised the following management plan: Early instability of an unlinked implant is due to either poor implant positioning or soft tissue balancing and is suitable for a one stage revision without the need for aspiration/drill biopsy. Late instability is due to implant wear or low grade infection. In this situation we regard an aspiration/drill biopsy as necessary. A negative result allows a one stage revision whereas a positive aspiration indicates the need for a two stage revision.
In a peri-prosthetic fracture if the bone cement mantle is intact a one stage revision without aspiration/ drill biopsy can be performed. If however, there is bone cement lucency we would advise an aspiration/ drill biopsy.
We have found the aspiration/drill biopsy helpful prior to revision total elbow replacement and we have used it to guide us as to whether a one or two stage procedure should be performed.
Displaced fractures of the distal humerus are very difficult to treat. Numerous techniques have been developed for internal fixation, e.g. plating, Rush nail fixation, IM nailing etc. Results are not very good in majority of the cases. Conventional ‘antigrade’ nailing sometimes may not be suitable for these types of fractures. This new nail is inserted by a close retrograde technique using a special interlocking system to avoid axillary nerve and rotator cuff damage. This nail also allows stable fixation of these distal fractures via a plate welded its distal end, which maintain the rotational stability.
Since 1997 we have treated 15 displaced extra particular fractures using this device. 12 of them were widely displaced fractures, some comminuted, and 3 were pathological fractures. The nail is introduced through the roof of the olecranon fossa, thus leaving the rotator cuff of the shoulder free from any iatrogenic injury. Proximal rotational stability is maintained by a unique ‘Trio Wire’, which passes through the nail and fans out in the head of the humerus. Distal rotational stability is maintained by the transverse plate.
In all cases early pain relief was obtained with return of shoulder and elbow functions. By 6 weeks 98% of patients could perform the majority of daily tasks. No significant complication was noted except a loss of extension of the elbow by 10–15 degrees
This new nail provides stable fixation of difficult distal humeral fractures, even in cases with poor bone quality. Early pain relief with a rapid return of shoulder and elbow functions denote a successful outcome of these operations.
This prospective evaluation of early experience using this technique. Patients with fracture of the distal clavicle were surgically treated with clavicular hook plate fixation. They were reviewed clinically and radiographically by one observer.
12 patients, 7 male, 5 female, were treated in our unit. Mean age (34.7) range 25–60 years. 10 were the results of low velocity injury.
9 were treated within one week of injury. 3 were treated at 13, 14 and 16 weeks post injury. Mean hospital stay 2.7 range 2–5 days. All patients healed, 10 within 12 weeks. All resumed full activity by 24 weeks. 2 had superficial wound infection, treated successfully with oral antibiotics without implant removal. One had a seroma, which resolved spontaneously. One patient developed limitation of movement at 20 weeks ultrasound confirmed impingement. Plate was removed and patient regained full range of movement after six weeks. No implant fracture or loosening was observed.
Based on experience to date the clavicular hook plate is a safe and reliable method of fixation. Relatively simple implant with good results. Allows early mobilisation and has little complication.
The purpose of this study was to design a clinically useful classification for distal humeral fractures that would provide guidance to the surgeon with regard to surgical approach and operative management.
This classification was assessed using the original radiographs from a study comparing distal humeral fracture classifications previously undertaken in Oxford, and validated using the exact methodology of that study. Nine independent assessors (3 orthopaedic consultants, 3 orthopaedic registrars and 3 musculoskeletal radiologists) were asked to classify 33 sets of radiographs on two separate occasions using the Riseborough and Radin, Jupiter and Mehne, and AO classifications as well as the new classification system. The assessors were unaware of the origin of the new system as this had been given a fictitious name. Using the Kappa statistic, the level of inter-observer and intra-observer agreement was determined and interpreted using the Landis and Koch criteria.
Amongst all observers, the new classification is both a substantially reliable (k=0.664) and reproducible (k=0.732) classification system. The new classification achieved superior inter- and intra-observer agreement compared to the other three classification systems with a low proportion of unclassifiable fractures comparable to the AO method (3.7%).
In reproducing materials and methodology from an independent study, we have been able to validate this new fracture classification system. Used in conjunction with a management algorithm, we believe the new classification aids the surgical decision-making process for these complex fractures.
The management of proximal humeral fractures is determined by fragment displacement. Intra-operative and radiological classification systems have been proposed, namely AO and the Neer classifications to assess therapeutic options.
This study evaluates the usefulness of these classification systems by the creation of physical 3D models using a rapid prototyping technique avoiding the problems associated with 3D illusions on a 2D screen.
Seven consecutive patients with complex fractures of the proximal humerus were investigated using the data from multi-sliced spiral CT scans. Fractures associated with dislocation were excluded. The data from these CTs was segmented to reveal the anatomy of interest and converted to a stereolithographic format from which the physical models could be made of the proximal humerus via a laser guided filament deposition process. Further manipulation with software allowed angulation and displacements of fragments to be measured.
Inter-observer agreement: All models were assessed by three surgeons. A consultant with a special interest in shoulder surgery, a fellowship trained surgeon and a senior house officer in basic surgical training. Independent assessment of the fractures from the models was made using the Neer and AO classifications. In only 1 incidence did all 3 observers agree on the classification, in 5 incidences only two observers agreed and on 8 occasions none of the observers agreed. Indeed there were 9 occasions that at least one observer thought the fracture pattern could not be applied to a classification.
Fracture Patterns: Observation of the individual models together with measurements of angulation and displacement by further software analysis, demonstrated major subtypes namely valgus and varus angulation with minimal displacement of the greater tuberosity. Appreciation of the integrity of the medial hinge and buckling could be made in relation to the different fracture patterns.
This study highlights concerns on the validity of current classification systems. It also questions whether the existing systems reflect the pathophysiological subtypes of these fractures allowing comparison of surgical results in order to evaluate treatment options.
Surgical joint stabilisation can be achieved by ligamentous plication or thermal shrinkage, and as such, we hypothesized that there is no difference in mechanical and morphological properties after reduction of laxity in ligaments treated by either technique.
Methods: 30 mature female rabbits underwent either ‘thermal’ treatment of their left medial collateral ligament (MCL) using a bipolar radiofrequency probe, or plication with two 4/O non-absorbable sutures following division along its midsubstance and loaded positioning of the free ends. After 12 weeks convalescence, the animals were euthanised and MCL complexes were procured from left and contralateral knees to undergo viscoelastic (creep) testing, quantitative Transmission Electron Microscopy (TEM) and immunohistochemistry. The TEM data was quantified by two data procurement protocols; computational analysis and manual graticule.
Mean creep strain in both thermal (1.85 +/− 0.32%) and plicated ligaments (1.92+/−0.36%) was almost twice that of the control (1.04+/−0.15%), although there was no difference between treatment modalities. Similar findings were seen in the thermal (1.77+/−0.45%), plication (1.85+/−0.40%) and control groups (0.92+/−0.20%) for viscoplastic deformation. However, collagen morphological parameters of all three groups were significantly different (p< 0.001). The thermal ligaments demonstrated predominantly small fibrils, whilst the plicated group displayed an intermediate distribution of heterogenous fibrils. Immunohistochemistry followed by TEM revealed a sparse random distribution of alpha-smooth muscle actin staining fibroblasyts in both thermal and plicated groups. There was an insignificant difference in computational and manual procurement methods (p=0.84).
Susceptibility to creep, and residual deformation after recovery, is similar after thermal shrinkage or plication, although inferior to intact ligaments. However, the plicated results suggest remodeling on a pre-existing fibrillar scaffold, yet the thermal group demonstrated histomorphometry similar to scar tissue, suggesting de novo synthesis. The absence of contractile myofibroblasts suggests that these cells may have an insignificant role in regulation of matrix tension during healing.
This study presents the clinical outcome of Boyd-McLeod procedure for lateral epicondylitis of elbow. 29 cases with lateral epicondylitis with failed conservative management (rest, physiotherapy, analgesia and steroid injections) were included in the study. There were 14 male, and 15 female cases of which two had bilateral surgery. Data collection included details of patients’ occupation, number of steroid injections, radiograph evaluation and postoperative complications. Post-operative clinical out come was evaluated by Hospital for Special Surgery Total Elbow Scoring System (HSS2), clinical notes review, and telephone questionnaire.
Average age: 47 years (range: 34–65), mean post-op follow up time: 16 months (range: 6–32). 93% were manual workers. Dominant elbow involvement was seen in 64%. Mean number of steroid injections: 3 (range: 1–10). Conservative measures included NSAIDS (90%) and physiotherapy (83%). Average tourniquet time: 32 min (range: 18–59). Mean HSS2 score pre-op and post-op were 38 and 92 respectively (p value: 0.0001). 91% reported excellent/good results. Average post-op time for the continuation of professional/recreational activity was 5 weeks. 2 cases (9%) had poor results. One case had ectopic bone formation.
Boyd-McLeod procedure is done as a day case procedure involving excision of degenerative tissue from common extensor origin, decortication and decompression of lateral epicondyle and partial release of annular ligament. Although an extensive procedure, this procedure addresses the management of all offending factors that are likely to contribute to pain and disability in tennis elbow. There are few studies regarding the outcome of Boyd-McLeod procedure. There was no evidence to suggest that late presentation had any adverse effect on the post-op success. This study revealed a high success rate and a low complication rate. We conclude that Boyd-McLeod procedure is an effective treatment option in patients with resistant lateral epicondylitis.
The study assesses the efficacy of commonly used suture materials with commonly described arthroscopic knotting techniques in as close a physiological pattern as possible.
The investigation was carried out in three phases. Initially the suture material strength was tested. The suture was then tested to failure using the different knotting techniques. Finally the test was repeated after soaking the suture with normal saline.
A Hounsfield tensometer was utilised with a load cell of 1000N, strain rate of 25mm/min, bar separation of 7.5mm and standard temperature and pressure. Suture material tested was 2 ethibond, 1 PDS and 1 Panacryl. Knotting techniques compared were the Tennessee slider, Tautline hitch, Duncan Loop, SMC knot and Surgeon’s knot. Two surgeons tied each knot 10 times after first becoming practiced with each technique. Each knot was tested to failure on 10 sequential experiments.
Ultimate strength of the suture material and of the knotting techniques was assessed. In addition the mode of failure, whether the knot slipped or suture material fractured was investigated.
As expected, 2 ethibond has a higher ultimate strength than either 1 PDS or 1 Panacryl. The Tautline hitch and Surgeon’s knot had a significantly lower slippage rate when compared to the other knotting techniques. (P value < 0.002). The Tennessee slider, Duncan Loop and SMC knots slipped in more than 50% of experiments. No difference was observed when the suture material had been soaked in normal saline. The number of half hitches required to provide maximum knot holding capacity was 3, confirming previous experimental findings by other investigators.
The Tautline hitch is recommended for use with all suture materials due to low slippage rates, ease of tying, ease of sliding and overall high knot strength
Although it is generally accepted that revision total elbow replacement may be necessary for loosening, instability, peri-prosthetic fracture and infection there is less agreement as to whether surgery should be performed as a one or two stage procedure. This can be of vital importance since the soft tissues around the elbow are often relatively poor making a single operation desirable. However, a one stage procedure in the presence of undetected low grade infection will result in joint failure with early loosening.
In our unit we have found the use of a preliminary aspiration/drill biopsy prior to revision surgery helpful in evaluating whether a one or two stage procedure should be performed.
Over an 8 year period 18 revision total elbow replacements have been undertaken. 9 patients were revised for aseptic loosening, 4 for proven infection, 3 for instability of an unlinked implant and 2 for peri-prosthetic fracture.
With this experience we have devised the following management plan.
Early instability of an unlinked implant is due to either poor implant positioning or soft tissue balancing and is suitable for a one stage revision without the need for aspiration/drill biopsy. Late instability is due to implant wear or low grade infection. In this situation we regard an aspiration/drill biopsy as necessary. A negative result allow a one stage revision whereas a positive aspiration indicates the need for a two stage revision.
In a peri-prosthetic fracture if the bone cement mantle is intact a one stage revision without aspiration/ drill biopsy can be performed. If, however, there is bone cement lucency we would advise an aspiration/ drill biopsy.
We have found the aspiration/drill biopsy helpful prior to revision total elbow replacement and we have used it to guide us as to whether a one or two stage procedure should be performed.
This study aimed to quantify the relationship between passive tension of rotator cuff repair and arm position intraoperatively and to examine the effect of the passive tension on gap formation in cadaveric rotator cuff repairs.
Five patients undergoing open surgical reconstruction of the rotator cuff were recruited. The operations were performed by a single surgeon using a standardised technique, which was acromioplasty, minimal debridement, mobilisation of tissue, bone troughs and transosseous suture tunnels.
A Differential Variable Reluctance Transducer (DVRT) was placed at the apex of the debrided tendon. An in situ calibration was performed to relate the output from the DVRT to actual tension in the tendon. The tension generated was recorded as the supraspinatus tendon was advanced into a bone trough and secured.
The relationship between arm position and repair tension was measured, by simultaneously collecting data from the DVRT and a calibrated goniometer. Particular attention was paid to the three standard positions of post-operative immobilisation; full adduction with internal rotation, neutral rotation with a 30° abduction wedge and ninety degrees of abduction.
Five cadaveric shoulders were used for the creation of standardised rotator cuff tears which were then repaired using the technique described above. The difference in tension measured between full adduction and 30° abduction was statically applied for twenty four hours and the gap formation measured.
Repair tension increased with advancement of the supraspinatus tendon into the bone trough. Abduction reduced the repair load, this was observed mainly in the first 30° of abduction. The mean reduction in load by 30° of abduction was 34 N.
Twenty four hours of 34N static loading caused gap formation in each cadaveric rotator cuff repairs, the mean was 9.2 mm.
Rotator cuff repairs tension can be reduced by postoperative immobilisation in 30° abduction. The change in tension with full adduction was caused gap formation in cadaveric rotator cuff repairs.