%0 Journal Article %A Jialuo Huang %A Jianrong Zheng %A Jianbin Yin %A Rengui Lin %A Junfeng Wu %A Hao-Ran Xu %A Jinjian Zhu %A Haiyan Zhang %A Guiqing Wang %A Daozhang Cai %T eIF5A downregulated by mechanical overloading delays chondrocyte senescence and osteoarthritis by regulating the CREBBP-mediated Notch pathway %D 2025 %J Bone & Joint Research %P 124-135 %V 14 %N 2 %R 10.1302/2046-3758.142.BJR-2024-0288.R1 %U https://doi.org/10.1302/2046-3758.142.BJR-2024-0288.R1 %K Osteoarthritis,Chondrocytes,eIF5A,Mechanical stress,CREBBP,Osteoarthritis (OA),chondrocytes,matrix metalloproteinase 13,staining,Quantitative polymerase chain reaction,strain,Western blot,collagen,Fast Green staining,cartilage