The aim of this study was to determine if a three-month course of microorganism-directed oral antibiotics reduces the rate of failure due to further infection following two-stage revision for chronic prosthetic joint infection (PJI) of the hip and knee. A total of 185 patients undergoing a two-stage revision in seven different centres were prospectively enrolled. Of these patients, 93 were randomized to receive microorganism-directed oral antibiotics for three months following reimplantation; 88 were randomized to receive no antibiotics, and four were withdrawn before randomization. Of the 181 randomized patients, 28 were lost to follow-up, six died before two years follow-up, and five with culture negative infections were excluded. The remaining 142 patients were followed for a mean of 3.3 years (2.0 to 7.6) with failure due to a further infection as the primary endpoint. Patients who were treated with antibiotics were also assessed for their adherence to the medication regime and for side effects to antibiotics.Aims
Methods
The aim of this study was to examine the results of the acetabular
distraction technique in achieving implantation of a stable construct,
obtaining biological fixation, and producing healing of chronic
pelvic discontinuity at revision total hip arthroplasty. We identified 32 patients treated between 2006 and 2013 who underwent
acetabular revision for a chronic pelvic discontinuity using acetabular
distraction, and who were radiographically evaluated at a mean of
62 months (25 to 160). Of these patients, 28 (87.5%) were female.
The mean age at the time of revision was 67 years (44 to 86). The patients
represented a continuous series drawn from two institutions that
adhered to an identical operative technique.Aims
Patients and Methods
A pelvic discontinuity occurs when the superior
and inferior parts of the hemi-pelvis are no longer connected, which
is difficult to manage when associated with a failed total hip replacement.
Chronic pelvic discontinuity is found in 0.9% to 2.1% of hip revision
cases with risk factors including severe pelvic bone loss, female
gender, prior pelvic radiation and rheumatoid arthritis. Common
treatment options include: pelvic plating with allograft, cage reconstruction,
custom triflange implants, and porous tantalum implants with modular augments.
The optimal technique is dependent upon the degree of the discontinuity,
the amount of available bone stock and the likelihood of achieving
stable healing between the two segments. A method of treating pelvic
discontinuity using porous tantalum components with a distraction
technique that achieves both initial stability and subsequent long-term
biological fixation is described. Cite this article:
