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The Journal of Bone & Joint Surgery British Volume
Vol. 73-B, Issue 3 | Pages 481 - 486
1 May 1991
Tregonning G Transfeldt E McCulloch J Macnab I Nachemson A

We reviewed two comparable groups of patients who had been treated for lumbar disc herniation by chymopapain chemonucleolysis (145) or conventional surgical discectomy (91). They were reviewed 10 years after treatment by questionnaire, followed by a personal interview by an independent observer. The results of the surgically treated groups were slightly better than those treated with chymopapain. In particular, there was significantly better early relief of leg and low back pain, and fewer patients needed a second procedure. Complications were few in both groups.


The Journal of Bone & Joint Surgery British Volume
Vol. 63-B, Issue 4 | Pages 504 - 507
1 Nov 1981
Kadziolka R Asztely M Hanai K Hansson T Nachemson A