Five children with chronic renal failure and severe rachitic deformities of the lower limbs were treated with 1 alpha-hydroxyvitamin D (1 alpha-OHD3) for 16 to 53 months. There was symptomatic, biochemical and radiological improvement in all five children and operative correction of their deformities was not needed. We recommend a trial of treatment with 1 alpha-OHD3 for this condition before surgical procedures.

From 1956 to 1965, congenital dislocation of the hip was treated in a standard manner in 191 cases. Reduction and plaster immobilisation was followed by a period in a Batchelor type plaster in full medial rotation. Femoral neck anteversion was then corrected by derotation osteotomy. In 95 children 117 hips were treated in this way and have been reviewed annually for 18 to 27 years. In 1983 they were assessed; there were 101 hips with good clinical results; radiologically, on a modified Severin scale, 62 were good, 39 were fair and 16 were poor. Derotation osteotomy proved to be the stimulus for growth of the acetabular roof in most cases; its safety, ease of performance and predictability suggest that it is superior to other methods of correcting the dysplasia.

An unusual form of chronic osteomyelitis in children is described. Three children presented with clinical signs of acute infection and radiographs revealed a pre-existing destructive bone lesion. Exploration of the lesions did not release pus, and cultures for pathogens were negative. The lesions healed but the symptoms returned intermittently over many years with the development of sclerosis and disturbance of bone growth. The lesions did not respond to antibiotics or operative treatment. All the patients were fully investigated and although the erythrocyte sedimentation rate was increased the white blood count was seldom abnormal. There were no neurological abnormalities. Two of the three cases required an osteotomy to correct malalignment. A comparison is made between the findings in these three patients with similar cases reported recently and possible causes are discussed.

Seven out of 22 children with monarticular juvenile rheumatoid arthritis (MJRA) developed involvement of other joints between six months and three and a half years from the onset. In the other 15 patients the disease has remained monarticular for between one and 16 years (mean six years). Chronic iridocyclitis was seen in three of the five boys, two with antinuclear antibodies. Children with MJRA and antinuclear antibodies should have periodic ophthalmic assessment. Synovial biopsy was of value primarily in excluding other cases of arthritis, but there was only limited correlation between the histological findings and the subsequent course of the disease.