Patients and Methods

A retrospective cohort study was conducted involving patients undergoing arthroplasty of the shoulder, at a single institution. Two patients with no previous bisphosphonate treatment were matched to each patient who had received this treatment preoperatively by gender, age, race, ethnicity, body mass index (BMI), and type of arthroplasty. Previous bisphosphonate treatment was defined as treatment occurring during the three-year period before the arthroplasty. The primary outcome measure was the incidence of intraoperative complications and those occurring at one and two years postoperatively. A total of 87 patients were included: 29 in the bisphosphonates-exposed (BP⁺) group and 58 in the non-exposed (BP^-) group. In the BP⁺ group, there were 26 female and three male patients, with a mean age of 71.4 years (51 to 87). In the BP^- group, there were 52 female and six male patients, with a mean age of 72.1 years (53 to 88).