We undertook this retrospective study to determine the rate of recurrence and functional outcome after intralesional curettage for chondroblastoma of
1. Experimental avascular necrosis of the femoral head was produced in rabbits and the histological and radiographic changes were compared. 2. Avascular
The major advantage of hip resurfacing is the decreased amount of
Objectives. We performed a systematic review of the literature to determine the safety and efficacy of
We studied the
1. Cancellous
1. The effects of the insertion of pieces of fresh cancellous
The efficacy of β-tricalcium phosphate (β-TCP) loaded with
The treatment of chronic osteomyelitis often
includes surgical debridement and filling the resultant void with antibiotic-loaded
polymethylmethacrylate cement, bone grafts or
Post-natal vasculogenesis, the process by which vascular committed bone marrow stem cells or endothelial precursor cells migrate, differentiate and incorporate into the nacent endothelium and thereby contribute to physiological and pathological neurovascularisation, has stimulated much interest. Its contribution to neovascularisation of tumours, wound healing and revascularisation associated with ischaemia of skeletal and cardiac muscles is well established. We evaluated the responses of endothelial precursor cells in
Specimens of femoral cortical
Atypical cartilaginous tumours are usually treated
by curettage. The purpose of this study was to show that radiofrequency
ablation was an effective alternative treatment. . We enrolled 20 patients (two male, 18 female, mean age 56 years
(36 to 72) in a proof-of-principle study. After inclusion, biopsy
and radiofrequency ablation were performed, followed three months
later by curettage and adjuvant phenolisation. The primary endpoint
was the proportional necrosis in the retrieved material. Secondary endpoints
were correlation with the findings on gadolinium enhanced MRI, functional
outcome and complications. Our results show that 95% to 100% necrosis was obtained in 14
of the 20 patients. MRI had a 91% sensitivity and 67% specificity
for detecting residual tumour after curettage. The mean functional
outcome (MSTS) score six weeks after radiofrequency ablation was
27.1 (23 to 30) compared with 18.1 (12 to 25) after curettage (p
<
0.001). No complications occurred after ablation, while two
patients developed a pathological fracture after curettage. We have shown that radiofrequency ablation is capable of completely
eradicating cartilaginous tumour cells in selective cases. MRI has
a 91% sensitivity for detecting any residual tumour. Radiofrequency
ablation can be performed on an outpatient basis allowing a rapid
return to normal activities. If it can be made more effective, it
has the potential to provide better local control, while improving
functional outcome. Cite this article:
Intra-articular resection of
The technique of storing
Vancomycin-supplemented allografts provide biological restoration of
Failure of
Resection of a primary sarcoma of the diaphysis
of a long
Implants of solid sintered hydroxyapatite form very tight bonds with living
Various chemicals are commonly used as adjuvant treatment to surgery for giant-cell tumour (GCT) of
1. In five series of experiments in eighty-two rabbits we succeeded in causing rarefaction of the calcaneum of all the animals soon after it was relieved from muscular compressing forces; new