Aims. Excessive chondrocyte hypertrophy is a common feature in cartilage degeneration which is susceptible to joint overloading, but the relationship between mechanical overloading and chondrocyte hypertrophy still remains elusive. The aim of our study was to explore the mechanism of mechanical compression-induced chondrocyte hypertrophy. Methods. In this study, the temporomandibular joint (TMJ) degeneration model was built through forced mandibular retrusion (FMR)-induced
Aims. To assess the cost-effectiveness of a two-layer
Limited access surgery is thought to reduce post-operative morbidity and provide faster recovery of function. The percutaneous
Objectives. The ability to determine human bone stiffness is of clinical relevance in many fields, including bone quality assessment and orthopaedic prosthesis design. Stiffness can be measured using
In this randomised controlled trial, we evaluated
the role of elastic
Metastatic epidural
Little is known about the efficacy of graduated
1. A series of twenty-three
Aims. Hindfoot arthrodesis with retrograde intramedullary nailing has
been described as a surgical strategy to reconstruct deformities
of the ankle and hindfoot in patients with Charcot arthropathy.
This study presents case series of Charcot arthropathy patients
treated with two different retrograde intramedullary straight compression
nails in order to reconstruct the hindfoot and assess the results
over a mid-term follow-up. Patients and Methods. We performed a retrospective analysis of 18 consecutive patients
and 19 operated feet with Charcot arthropathy who underwent a hindfoot
arthrodesis using a retrograde intramedullary
In a prospective study between August 2002 and August 2005, we studied the quantitative clinical and radiological outcome 36 months after percutaneous vertebroplasty for intractable type-II osteoporotic vertebral
Objectives. External fixators are the traditional fixation method of choice for contaminated open fractures. However, patient acceptance is low due to the high profile and therefore physical burden of the constructs. An externalised locking
We describe an operation to relieve
We analysed the influence of the timing of surgery (<
48 hours, group 1, 21 patients vs >
48 hours, group 2, 14 patients) on the neurological outcome and restoration of mobility in 35 incomplete tetra- and paraplegic patients with metastatic spinal-cord
We present the clinical and radiological results of percutaneous vertebroplasty in the treatment of 58 vertebral
Spinal nerve roots often sustain
We recruited 89 patients who had hip or knee replacements to assess the performance of below-knee graded
We investigated the safety and efficacy of treating osteoporotic vertebral
We studied retrospectively the results in 24 patients (25 feet) who had been treated by subtalar arthrodesis with internal
Deep vein thrombosis is a common complication
of immobilising the lower limb after surgery. We hypothesised that
intermittent pneumatic