Advertisement for orthosearch.org.uk
Results 1 - 1 of 1
Results per page:
The Journal of Bone & Joint Surgery British Volume
Vol. 78-B, Issue 2 | Pages 210 - 212
1 Mar 1996
Laupacis A Rorabeck C Bourne R Tugwell P Bullas R Rankin R Vellet AD Feeny D Wong C

We randomised 250 patients undergoing unilateral, elective hip arthroplasty for osteoarthritis to receive either a cemented or a non-cemented Mallory Head prosthesis. Aspirin was used as prophylaxis against thromboembolism during the first half of the study and adjusted-dose warfarin during the second half. Postoperatively, all patients were asked to have bilateral venography and 80% agreed. All were evaluated clinically for pulmonary embolism.

There was no difference in the frequency of deep-venous thrombosis between the two groups (50% cemented v 47% non-cemented, p = 0.73; 95% CI of the difference −13.6% to 19.3%). Three of the 64 patients (5%) in whom venography had demonstrated isolated distal thrombi developed pulmonary emboli.