Introduction: Clear cell sarcoma is a very rare tumor of the tissues described also as melanoma of the tissues. It is a low-grade tumor mostly located in the hand.

Aim: To present 3 patients with this rare tumor located in the hand and to describe the therapy, which is wide or radical excision after control of the local lymphnodes

Methods-materials: We present three patients treated in our department the last 3 years. The tumor was located at the ring finger, the little finger and in the thenar. All the patients primary were treated at an other center with insufficient removal of the tumor. At the time they presented in our department they all had local recurrence.

At our hospital after control of the local lymphnodes (with MRI or scanning), which was negative, two patients were treated with ray amputation and the patient with tumor location in the thenar was treated with wide local excision and skin grafting. By the histological examination the surgical margins in all patients were clear and so Ro therapy or chemotherapy were not further needed. All patients returned to their primary work. Until now we have no further recurrence.

Conclusions: Clear cell sarcoma of the hand is a rare tumor of the tissues with low-grade malignancy and good prognosis if treated by wide excision. Ray amputation gives an excellent therapeutic and functional outcome.