Advertisement for orthosearch.org.uk
Results 1 - 7 of 7
Results per page:
Orthopaedic Proceedings
Vol. 94-B, Issue SUPP_III | Pages 58 - 58
1 Feb 2012
Hook S Moulder E Burston B Yates P Whitley E Bannister G
Full Access

We reviewed 142 consecutive primary hip arthroplasties using the Exeter Universal femoral stem implanted between 1988 and 1993 into 123 patients. 74 patients with 88 hips survived to 10 years or more and were reviewed with a mean 12 years 8 months. There was no loss to follow-up and the fate of all stems is known.

Our stem revision rate for aseptic loosening and osteolysis was 1.1% (1 stem); stem revision for any cause was 2.2% (2 stems); and re-operation for any cause was 21.6% (19 hips), all but 2 of which were due to cup failure.

All but one stem subsided within the cement mantle to an average of 1.5mm at final follow-up (0 to 8mm). One stem was revised for deep infection and one was revised for excessive periarticular osteolysis. One further stem had subsided excessively (8mm) and demonstrated lucent lines at the stem-cement and cement-bone interfaces. This was classified as a radiological failure and is awaiting revision. 28% of stems had cement mantle defects, which were associated with increased subsidence (p=0.01), but were not associated with endosteal lysis or stem failure.

Periarticular osteolysis was significantly related with the degree of polyethylene wear (p<0.001), which was in turn associated with younger age patients (p=0.01) and males (p<0.001).

The Exeter metal backed cups were a catastrophic failure with 34% revised (11 cups) for loosening. The Harris Galante cups failed with excessive wear and osteolysis, with failure to revision of 18%. Only 1 cemented Elite cup was revised for loosening and osteolysis (4%).

The Exeter Universal stem implanted outside the originator centre has excellent medium term results.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 504 - 504
1 Aug 2008
Ramiah RD Ashmore AM Whitley E Bannister GC
Full Access

We have determined the 10 year life expectancy of 5,831 patients who had undergone 6,653 elective primary total hip replacements (THR) at a regional orthopaedic centre between April 1993 and October 2004.

Methods: We ascertained dates of deaths for all those who had undergone surgery during this period and constructed Kaplan Meier survivorship curves for these patients. Standardized mortality ratios were calculated by comparing this data with available UK mortality rates for the same age groups over the same time period.

Results: The mean age at operation was 73 with a male to female ratio of 2:3. Of those with 10 year follow up 29.5% had died a mean of 5.6 years after surgery. 10-year survivorship was 89% in patients under 65 years at surgery, 75% in patients aged between 65 – 74 years and 51% in patients over 75.

The standard mortality rates were significantly higher than expected for patients under 45 years, 20% higher for those between 45 and 64 years and progressively less than expected for patients aged 65 and over.

Discussion: By comparing our mortality curves with prosthesis survivorship curves from the most recent Swedish Arthroplasty Register results we were able to demonstrate that the survivorship of cemented hip arthroplasties exceeds that of the patients over the age of 60 in our area. As these prostheses are less expensive than their uncemented equivalents this suggests these are the prosthesis of choice in this age group.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 540 - 540
1 Aug 2008
Ramiah RD Ashmore AM Whitley E Bannister GC
Full Access

We determined the 10 year life expectancy of 5,831 patients who had undergone 6,653 elective primary total hip replacements (THR) at a regional orthopaedic centre between April 1993 and October 2004. Using Hospital, General Practitioner (GP) and the local health authority’s records, we determined dates of deaths for all those who had undergone surgery during this period.

The mean age at operation was 73 (13–96) with a male to female ratio of 2:3. Of those with 10 year follow up 29.5% had died a mean of 5.6 (0–11.1) years after surgery. Using Kaplan Meier curves, 10-year survivorship was 89% in patients under 65 years at surgery, 75% in patients aged between 65 – 74 years and 51% in patients over 75.

The standardised mortality rates (SMR) were significantly higher than expected for patients under 45 years, 20% higher for those between 45 and 64 years and progressively less than expected for patients aged 65 and over.

The survivorship of cemented hip arthroplasties (derived from the Swedish Arthroplasty Register 2004) exceeds patients’ life expectancy in those over the age of 60 in our area suggesting that this is the procedure of choice in this population.


Orthopaedic Proceedings
Vol. 90-B, Issue SUPP_III | Pages 503 - 504
1 Aug 2008
Burston B Yates P Hook S Moulder E Whitley E Bannister G
Full Access

The success of total hip replacement in the young has consistently been worse both radiologically and clinically when compared to the standard hip replacement population.

Methods: We describe the clinical and radiological outcome of 58 consecutive polished tapered stems (PTS) in 47 patients with a minimum of 10 years follow up (mean 12 years 6 months) and compared this to our cohort of standard patients. There were 22 CPT stems and 36 Exeter stems.

Results: Three patients with 4 hips died before 10 years and one hip was removed as part of a hindquarter amputation due to vascular disease. None of these stems had been revised or shown any signs of failure at their last follow-up. No stems were lost to follow up and the fate of all stems is known. Survivorship with revision of the femoral component for aseptic loosening as the endpoint was zero and 4% (2 stems) for potential revision. The Harris hip scores were good or excellent in 81% of the patients (mean score 86).

All the stems subsided within the cement to a mean total of 1.8mm (0.2–8) at final review. There was excellent preservation of proximal bone and an extremely low incidence of loosening at the cement bone interface. Cup failure and cup wear with an associated periarticular osteolysis was a serious problem. 19% of the cups (10) were revised and 25% of the hips (13) had significant periarticular osteolysis associated with excessive polyethylene wear.

Discussion: The outcome of polished tapered stems in this age group is as good as in the standard age group and superior to other non PTS designs in young patients. This is despite higher weight and frequent previous surgery. Cup wear and cup failure were significantly worse in this group, with a higher incidence of periarticular osteolysis.


The Journal of Bone & Joint Surgery British Volume
Vol. 90-B, Issue 1 | Pages 16 - 22
1 Jan 2008
Yates PJ Burston BJ Whitley E Bannister GC

We retrospectively reviewed 175 patients (191 hips) who had undergone primary cemented total hip replacement between November 1992 and November 1995 using a collarless polished double-tapered femoral component after a minimum of ten years (mean 11.08; 10 to 12.8). All stems were implanted using contemporary cementing techniques with a distal cement restrictor, pressurised lavage, retrograde cementing with a gun and proximal pressurisation. Clinical outcome was assessed using the Harris Hip score. Radiological analysis was performed on calibrated plain radiographs taken in two planes. Complete radiological data on 110 patients (120 hips) and clinical follow-up on all the surviving 111 patients (122 hips) was available. The fate of all the hips was known.

At final follow-up, the mean Harris Hip score was 86 (47 to 100), and 87 of 116 patients (75%) had good or excellent scores. Survival with revision of the stem for aseptic loosening as the endpoint was 100%; and survival with revision of the stem for any reason was 95.9% (95% confidence interval 87.8 to 96.8) at ten years. All the stems subsided vertically at the stem-cement interface in a predictable pattern, at an overall mean rate of 0.18 mm per year (0.02 to 2.16), but with a mean rate of 0.80 mm (0.02 to 2.5) during the first year. The mean total subsidence was 1.95 mm (0.21 to 24). Only three stems loosened at the cement-bone interface. There was excellent preservation of proximal femoral bone stock. There was a high incidence of Brooker III and IV heterotopic ossification affecting 25 patients (22%).

The collarless polished tapered stem has an excellent clinical and radiological outcome at a minimum of ten years’ follow-up. The pattern and magnitude of subsidence of the stem within the cement mantle occurred in a predictable pattern, consistent with the design philosophy.


The Journal of Bone & Joint Surgery British Volume
Vol. 89-B, Issue 10 | Pages 1299 - 1302
1 Oct 2007
Ramiah RD Ashmore AM Whitley E Bannister GC

We determined the ten-year life expectancy of 5831 patients who had undergone 6653 elective primary total hip replacements at a regional orthopaedic centre between April 1993 and October 2004. Using hospital, general practitioner and the local health authority records, we recorded the dates of death for those who died following surgery.

The mean age at operation was 67 years (13 to 96) with a male:female ratio of 2:3. Of 1154 patients with a ten-year follow-up 340 (29.5%) had died a mean of 5.6 years (0 to 10) after surgery. Using Kaplan-Meier curves, the ten-year survival was 89% in patients under 65 years at surgery, 75% in patients aged between 65 and 74 years, and 51% in patients over 75.

The standardised mortality rates were considerably higher for patients under 45 years, 20% higher for those between 45 and 64 years, and steadily reduced in patients aged 65 and over.

The survival of cemented hip replacement derived from the Swedish Hip Arthroplasty Register Annual Report 2004 exceeds the life expectancy of patients over the age of 60 in our area, suggesting that cemented hip replacement is the procedure of choice in this population.


The Journal of Bone & Joint Surgery British Volume
Vol. 88-B, Issue 12 | Pages 1584 - 1590
1 Dec 2006
Hook S Moulder E Yates PJ Burston BJ Whitley E Bannister GC

We reviewed 142 consecutive primary total hip replacements implanted into 123 patients between 1988 and 1993 using the Exeter Universal femoral stem. A total of 74 patients (88 hips) had survived for ten years or more and were reviewed at a mean of 12.7 years (10 to 17). There was no loss to follow-up.

The rate of revision of the femoral component for aseptic loosening and osteolysis was 1.1% (1 stem), that for revision for any cause was 2.2% (2 stems), and for re-operation for any cause was 21.6% (19 hips). Re-operation was because of failure of the acetabular component in all but two hips.

All but one femoral component subsided within the cement mantle to a mean of 1.52 mm (0 to 8.3) at the final follow-up. One further stem had subsided excessively (8 mm) and had lucent lines at the cement-stem and cement-bone interfaces. This was classified as a radiological failure and is awaiting revision. One stem was revised for deep infection and one for excessive peri-articular osteolysis. Defects of the cement mantle (Barrack grade C and D) were found in 28% of stems (25 hips), associated with increased subsidence (p = 0.01), but were not associated with endosteal lysis or failure.

Peri-articular osteolysis was significantly related to the degree of polyethylene wear (p < 0.001), which was in turn associated with a younger age (p = 0.01) and male gender (p < 0.001).

The use of the Exeter metal-backed acetabular component was a notable failure with 12 of 32 hips (37.5%) revised for loosening. The Harris-Galante components failed with excessive wear, osteolysis and dislocation with 15% revised (5 of 33 hips). Only one of 23 hips with a cemented Elite component (4%) was revised for loosening and osteolysis.

Our findings show that the Exeter Universal stem implanted outside the originating centre has excellent medium-term results.